Medicinal particle filtering device

Abstract

The utility model discloses a medicinal particle filtering device which comprises a barrel-shaped body, an opening in the top end of the barrel-shaped body is a material taking opening, an opening in the bottom end of the barrel-shaped body is a liquid discharging opening, and a filter screen is installed in the barrel-shaped body. The filter screen is parallel to the material taking opening and the liquid discharging opening; a feeding port is formed in the side face of the barrel-shaped body, the position of the feeding port is higher than the position of the filter screen, and the feeding port is connected with a feeding pipeline. According to the filtering device disclosed by the utility model, the position of the lateral feeding channel is reasonably configured, so that a special liquid flowing mode is realized, a sample to be filtered is spontaneously enriched towards the center of the filter screen through the Bernoulli effect in the device, medicine particles are prevented from being accumulated on the whole filter screen, the self-cleaning function of the device is realized, and the service life of the device is prolonged. Convenience is brought to sample collection while the filtering efficiency is improved, the sample transfer efficiency is effectively improved, the labor intensity of workers is reduced, and industrial production is facilitated.

Description

Technical Field

[0001] The utility model belongs to the technical field of screening equipment, and in particular relates to a filtering device which can be self-cleaned and is suitable for micron-level medicinal particles. Background Art

[0002] In the process of drug production, it is often necessary to purify and collect drugs, such as filtering crystalline drug particles together with solutions to achieve solid-liquid separation, and purifying, washing, and concentrating drug-containing suspensions (liposomes, microspheres, microcrystals, etc.) by filtering. Conventional filtration methods are mainly dead-end filtration, that is, the drug solution flows through the filter in a direction perpendicular to the filter under a certain driving force or suction force, and particles smaller than the filter mesh aperture are intercepted during the flow process. Due to the small particle size, as the filtration process proceeds, the particle accumulation causes the filtration resistance to rise rapidly, and the filtration speed continues to slow down. In order to improve the filtration efficiency, it is often necessary to increase the effective filtration area or backwash the filter, which significantly increases the drug production cost and production energy consumption; in addition, when transferring samples, the drug is fully covered on the filter and accumulated into a dense cake layer, making sample collection difficult, and there is obvious drug residue in the filter and its surroundings, resulting in reduced sample transfer efficiency and reduced final product output, making it difficult to achieve industrial scale-up production.

[0003] Therefore, how to avoid the phenomenon of filter screen clogging easily in traditional dead-end filtration, improve drug filtration effect, and increase drug yield is an urgent problem to be solved in this field. Utility Model Content

[0004] The purpose of the utility model is to provide a self-cleaning filtering device suitable for micron-sized medicinal particles, so as to improve the filtering effect of the medicinal liquid, enhance the convenience of operation, and solve the problems of filter blockage, low sample yield, etc. proposed in the above background technology.

[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0006] A medicinal particle filtering device comprises a cylindrical body, wherein the top opening of the cylindrical body is a material taking port, the bottom opening is a liquid discharge port, and a filter screen is installed in the cylindrical body; the filter screen is arranged in parallel with the material taking port and the liquid discharge port;

[0007] A feed inlet is provided on the side of the cylindrical body. The position of the feed inlet is higher than the position of the filter screen. The feed inlet is connected to a feed pipeline.

[0008] The discharge port is designed as a quick-release chuck. After being matched with a sealing gasket and a clamp, it can be quickly connected to a pipeline system of suitable size to facilitate the discharge of the filtered liquid. The material extraction port is designed as a quick-release chuck. With a sealing gasket, a clamp, a blind plate or similar components, a sealing structure can be formed on one side of the filter material, which can withstand a pressure of no more than 3 bar and can be quickly disassembled and assembled to collect the material on the filter.

[0009] Furthermore, the cross-section of the cylindrical body is quadrilateral or circular.

[0010] Furthermore, the Ra of the circle is less than 0.3, and the diameter is 10cm-50cm.

[0011] Furthermore, the angle between the center line of the feed port and the filter is 1°-60°, and the distance from the projection of the feed port on the filter to the center of the filter is 50%-95% of the radius of the filter.

[0012] Furthermore, the filter screen is a multi-layer sintered mesh made of stainless steel, or a stainless steel woven mesh with a supporting structure.

[0013] Furthermore, the filter mesh has an aperture of 10 μm-800 μm.

[0014] Furthermore, the ratio of the diameter of the feed pipeline to the diameter of the filter screen is in the range of 0.006-0.4.

[0015] Compared with the prior art, the beneficial effects of the utility model are as follows:

[0016] 1. This device realizes a special liquid flow mode by rationally configuring the position of the lateral feed channel. The sample to be filtered is spontaneously enriched to the center of the filter screen through the Bernoulli effect in the device, avoiding the accumulation of drug particles on the entire filter screen, realizing the self-cleaning function of the device, improving the filtration efficiency and bringing convenience to sample collection, effectively improving the transfer efficiency of the sample, reducing the labor intensity of the staff, and facilitating industrial production.

[0017] 2. This device does not contain any moving parts and does not require external power supply. The power for filtering and self-cleaning comes from the kinetic energy of the material at the feed inlet. It is easy to use, maintain, energy-saving and environmentally friendly, and effectively reduces the production cost of medicines.

[0018] 3. This device can be connected to the corresponding blind plate and discharge pipeline through the quick-release connectors of the discharge port and the material taking port, which can isolate the material from the external environment. It is suitable for the production of sterile raw materials and sterile preparations and has good application prospects. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 This is a schematic diagram of the structure of the filter device of the utility model;

[0020] Figure 2 It is a side view structural schematic diagram of the filter device of the utility model;

[0021] Among them: 1 is the cylindrical body, 2 is the filter screen, 3 is the feed pipeline, 4 is the drain port, and 5 is the liquid outlet. DETAILED DESCRIPTION

[0022] The following will be combined with the drawings of the utility model to clearly and completely describe the technical solution of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0023] like Figure 1 As shown, the utility model provides a medicinal particle filtering device, comprising a cylindrical body 1, the cylindrical body 1 is hollow and has openings at both ends. The top opening of the cylindrical body 1 is a material taking port 5, and the bottom opening is a liquid discharge port 4. A filter screen 2 is installed in the cylindrical body 1, and the position of the filter screen 2 is parallel to the liquid inlet 4 and the liquid outlet 5.

[0024] A feed port is provided on the side of the cylindrical body 1 . The position of the feed port is higher than the filter screen 2 . The feed port is connected to the feed pipeline 3 .

[0025] When in use, thoroughly clean the filtering device of the utility model, first connect the drain port 4 to the drain pipeline, install a sealing gasket and fix it with a clamp; then connect the feed port 5 to the blind plate, also install a sealing gasket and fix it with a clamp; then connect the side feed pipeline 3 to the discharge port of the equipment equipped with the liquid medicine to be filtered.

[0026] After everything is ready, the compressed air is charged into the device containing the drug liquid to be filtered. When the pressure reaches the requirement, the discharge port of the device is opened, and the drug liquid enters the filter device of the utility model from the feed pipeline 3 and filters and enriches the drug particles through the filter screen 2; when the drug liquid to be filtered flows out completely, the discharge port of the device is closed, and the solvent for washing the drug particles is added to the device, and the compressed air is recharged into the device. When the pressure reaches the requirement, the discharge port of the device is opened again, and the washing solvent is allowed to enter the filter device of the utility model from the feed pipeline 3 and wash the particles enriched on the filter screen 2. Repeat the above operation several times to fully wash the drug particles.

[0027] After cleaning, keep the discharge port of the equipment open and continue to fill the equipment with compressed air. At this time, the water on the filter screen 2 is gradually squeezed out and drained. Close the discharge port of the equipment, wait for the pressure to balance, and remove the clamp at the material taking port 5. At this time, it can be seen that the drug particles are enriched in the center of the filter screen 2 and piled up in a pagoda shape. After transfer, the next step of drug particle operation can be continued.

[0028] In the utility model, the cross section of the cylindrical body is a quadrilateral or a circle. When the cross section is a circle, the Ra of the circle is less than 0.3, and the diameter is 10cm-50cm.

[0029] In the present invention, the angle between the center line of the feed port and the filter is preferably 1°-60°, and the distance from the projection of the feed port on the filter to the center of the filter is preferably 50%-95% of the radius of the filter.

[0030] In the utility model, the angle between the center line of the feed port and the filter screen is 1°-60°, and the distance from the projection of the feed port on the filter screen to the center of the filter screen is 50%-95% of the radius of the filter screen;

[0031] In the utility model, the filter screen is a multi-layer sintered screen made of stainless steel, or a stainless steel woven screen with a supporting structure.

[0032] In the utility model, the pore size of the filter screen is 10 μm-800 μm.

[0033] In the present invention, the ratio of the diameter of the feed channel to the diameter of the filter screen is in the range of 0.006-0.4.

[0034] In the utility model, the material taking port is designed as a quick-release chuck, which, in conjunction with a sealing gasket, a clamp, a blind plate or similar components, can form a sealing structure on one side of the filter material, can withstand a pressure not exceeding 3 bar, and can be quickly disassembled and assembled to collect the material on the filter.

[0035] In the utility model, the liquid discharge port is designed as a quick-install chuck, which can be quickly connected to a pipeline system of suitable size after being matched with a sealing gasket and a clamp, so as to facilitate the discharge of the filtered liquid.

[0036] The principles and implementation methods of the present invention are described in this article using specific embodiments. The description of the above embodiments is only used to help understand the method and core idea of ​​the present invention. It should be pointed out that for ordinary technicians in this technical field, it can be understood that without departing from the principles and spirit of the present invention, the present invention can also be subjected to various changes, not limited to several improvements, replacements, modifications and variations, and these changes also fall within the scope of protection of the claims of the present invention.

Claims

1. A medicinal particle filtering device, characterized in that: It comprises a cylindrical body (1), the top opening of the cylindrical body (1) is a material taking port (5), the bottom opening is a liquid discharge port (4), a filter screen (2) is installed in the cylindrical body (1), and the filter screen (2) is arranged parallel to the material taking port (5) and the liquid discharge port (4); A feed inlet is provided on the side of the cylindrical body (1), the position of the feed inlet being higher than the position of the filter screen (2), and the feed inlet being connected to a feed pipeline (3).

2. The medicinal particle filtering device according to claim 1, characterized in that: The cross section of the cylindrical body (1) is quadrilateral or circular.

3. The medicinal particle filtering device according to claim 2, characterized in that: The Ra of the circle is less than 0.3, and the diameter is 10cm-50cm.

4. The medicinal particle filtering device according to claim 1, characterized in that: The angle between the center line of the feed port and the filter screen (2) is 1°-60°, and the distance from the projection of the feed port on the filter screen (2) to the center of the filter screen (2) is 50%-95% of the radius of the filter screen (2).

5. The medicinal particle filtering device according to claim 1, characterized in that: The filter screen (2) is a multi-layer sintered screen made of stainless steel, or a stainless steel woven screen with a supporting structure.

6. The medicinal particle filtering device according to claim 1, characterized in that: The mesh size of the filter (2) is 10 μm-800 μm.

7. The medicinal particle filtering device according to claim 1, characterized in that: The ratio of the diameter of the feed pipeline (3) to the diameter of the filter screen (2) is in the range of 0.006-0.4.

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