Online ionization inert through pipe device

Abstract

The utility model relates to the technical field of detection, and discloses an online ionization inert through pipe device which comprises a mass spectrometer, the side edge of the mass spectrometer is communicated with an SICRIT source, the end part of the SICRIT source is communicated with a connecting bent pipe, and the bottom end of the connecting bent pipe is communicated with an inert through pipe. The end part of the SICRIT source is communicated with the inert through pipe through the arranged connecting bent pipe, so that the inert through pipe can extend into the upper end of the sample bottle, and the SICRIT source can directly suck gas from a sample through the inert through pipe, thereby realizing the focusing effect on the gas and improving the ionization efficiency of the SICRIT; according to the present invention, the interaction between the material and the sample can be reduced, the possible pollution and interference can be reduced, the accuracy of the experiment result can be improved due to the existence of the online ionization inert through pipe, and the concentration of the gas in the sample is uniform and stable so as to ensure the reliability and the repeatability of the experiment data.

Description

Technical Field

[0001] The utility model relates to the field of biotechnology, in particular to an online ionization inert pipe-clearing device. Background Art

[0002] SICRIT is a flow-through medium-path discharge source technology used to ionize gas samples and provide a stable ion source environment. SICRIT's unique ionization principle can achieve non-discriminatory simultaneous ionization of weak polar, non-polar trace and ultra-trace targeted or non-targeted marker molecules, greatly improving the molecular detection coverage, specificity, and recognition sensitivity. Therefore, ICRIT has been widely used in many fields, such as identifying chemical toxins, flavor species, co-diagnosing key disease changes (including health and symptom identification), monitoring food and drug adulteration, and drug distribution and toxin migration, and obtaining spatial distribution information of chemical and biological molecules in materials, food and drugs, and animal and plant tissues.

[0003] SICRIT uses negative pressure to inhale and ionize volatile substances in the sample to be tested. The ionized sample enters the mass spectrometer to complete the detection. However, in the olfactory injection mode of the existing SICRIT, there is a certain distance between the sample bottle and the SICRIT source. The gas will undergo uncontrollable exchange with the air within the distance between the sample bottle and the SICRIT source, resulting in dilution of the gas sample, inability to ensure the stability of the medium path, reduced ionization efficiency, and poor reproducibility between parallel samples. Utility Model Content

[0004] In view of the deficiencies in the prior art, the utility model provides an online ionization inert pipe device, which solves the problem that in the existing SICRIT olfactory sampling mode, there is a certain distance between the sample bottle and the SICRIT source, and the gas will undergo uncontrollable exchange with the air within the distance between the sample bottle and the SICRIT source, resulting in dilution of the gas sample, the stability of the medium passage cannot be guaranteed, the ionization efficiency is reduced, and the reproducibility between parallel samples is deteriorated.

[0005] The utility model provides the following technical solution: an online ionization inert through-tube device, comprising a mass spectrometer, a side of the mass spectrometer is connected to a SICRIT source, an end of the SICRIT source is connected to a connecting elbow, a bottom end of the connecting elbow is connected to an inert through-tube, and a bottle mouth sealing assembly for sealing is slidably arranged on the inert through-tube;

[0006] The bottle mouth sealing assembly includes a movable sleeve sleeved on the inert through tube, two inner cavity grooves are symmetrically provided on both sides of the inner wall of the movable sleeve, a fixed resistance plate is slidably provided in the inner cavity groove, two pulling through holes are symmetrically provided on the inner wall of the inner cavity groove, a resistance push rod is slidably inserted in the pulling through hole, the end of the resistance push rod is connected to the side wall of the fixed resistance plate, the ends of the two resistance push rods are connected by an external connecting plate, a resistance spring is sleeved on the resistance push rod, one end of the resistance spring is connected to the external connecting plate, and the other end of the resistance spring is connected to the outer wall of the movable sleeve.

[0007] Preferred technical solution one: a bottom annular groove is provided at the bottom end of the movable sleeve, a sealing rubber pad is provided below the bottom annular groove, two bottom grooves are symmetrically provided on the inner wall of the bottom annular groove, the top end of the sealing rubber pad is slidably inserted into the bottom groove through a connecting rod, a connecting spring is provided in the bottom groove, one end of the connecting spring is connected to the inner wall of the bottom groove, and the other end of the connecting spring is connected to the connecting rod.

[0008] Preferred technical solution 2: The connecting elbow is bent at 90 degrees.

[0009] Preferred technical solution three: the inert through-tube is made of inert material glass.

[0010] This solution can make the inert through-tube have higher chemical stability and corrosion resistance, and will not pollute or interfere with the gas in the sample.

[0011] Preferred technical solution 4: The side surface of the fixed abutment plate is in an arc shape that fits the inertia through pipe.

[0012] This solution can make the fixed contact plate better contact and fix with the inertia through pipe under the elastic contact of the contact spring.

[0013] Preferred technical solution five: the sealing rubber pad is in a ring shape, and the inner wall of the sealing rubber pad is in contact with the inert through pipe.

[0014] This solution enables the inert through tube to be better sealed under the resistance of the sealing rubber pad after being inserted into the sample bottle.

[0015] Compared with the prior art, the utility model provides an online ionization inert pipe-passing device, which has the following beneficial effects:

[0016] (1) The utility model provides a SICRIT source on the side of the mass spectrometer, and the end of the SICRIT source is connected to the inert through-tube through a connecting elbow, so that the inert through-tube can extend into the upper end of the sample bottle. The SICRIT source can directly inhale gas from the sample through the inert through-tube, thereby achieving a focusing effect on the gas and improving the ionization efficiency of SICRIT.

[0017] (2) The use of an online ionization inert tube can also prevent the dilution of the gas in the sample. Under normal experimental conditions, the gas in the sample will exchange or mix with the air in the environment in an uncontrollable manner, reducing the concentration of the gas sample. When the inert tube is extended into the upper end of the sample bottle, the dilution of the gas sample can be avoided as much as possible.

[0018] (3) The online ionization inert tube is made of inert materials, which have high chemical stability and corrosion resistance. By using the tube made of inert materials, the interaction between the material and the sample can be reduced, reducing possible contamination and interference.

[0019] The presence of an online ionization inert tube can improve the accuracy of the experimental results. By reducing gas dilution and preventing the exchange of samples with air, the gas concentration in the sample is more uniform and stable, thereby ensuring the reliability and repeatability of the experimental data. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the main structure of the utility model;

[0021] Figure 2 For the utility model Figure 1 A magnified view of the structure of the middle bottle mouth sealing assembly;

[0022] Figure 3 For the utility model Figure 2 A magnified view of the structure of the pull-through hole;

[0023] Figure 4 For the utility model Figure 2 Enlarged view of the structure of the middle and bottom annular groove.

[0024] In the figure:

[0025] 1. Mass spectrometer; 2. SICRIT source; 3. Connecting elbow; 4. Inert through pipe; 5. Bottle mouth sealing assembly;

[0026] 501, movable sleeve; 502, inner cavity groove; 503, fixed resistance plate; 504, pulling through hole; 505, resistance push rod; 506, external connecting plate; 507, resistance spring; 508, bottom annular groove; 509, sealing rubber pad; 510, bottom groove; 511, connecting rod; 512, connecting spring. DETAILED DESCRIPTION

[0027] See also Figure 1-4

[0028] Embodiment 1: An online ionization inert through-tube device comprises a mass spectrometer 1, a SICRIT source 2 is connected to the side of the mass spectrometer 1, a connecting elbow 3 is connected to the end of the SICRIT source 2, an inert through-tube 4 is connected to the bottom end of the connecting elbow 3, and a bottle mouth sealing assembly 5 for sealing is slidably provided on the inert through-tube 4.

[0029] The bottle mouth sealing assembly 5 includes a movable sleeve 501 sleeved on the inert through tube 4, and two inner cavity grooves 502 are symmetrically provided on both sides of the inner wall of the movable sleeve 501, and a fixed abutment plate 503 is slidably provided in the inner cavity groove 502, and two pulling through holes 504 are symmetrically provided on the inner wall of the inner cavity groove 502, and an abutment push rod 505 is slidably inserted in the pulling through hole 504.

[0030] The end of the resistance push rod 505 is connected to the side wall of the fixed resistance plate 503, and the ends of the two resistance push rods 505 are connected by an external connecting plate 506. A resistance spring 507 is sleeved on the resistance push rod 505, one end of the resistance spring 507 is connected to the external connecting plate 506, and the other end of the resistance spring 507 is connected to the outer wall of the movable sleeve 501.

[0031] A bottom annular groove 508 is provided at the bottom end of the movable sleeve 501, a sealing rubber pad 509 is arranged below the bottom annular groove 508, two bottom grooves 510 are symmetrically provided on the inner wall of the bottom annular groove 508, the top end of the sealing rubber pad 509 is slidably inserted into the bottom groove 510 through a connecting rod 511, a connecting spring 512 is arranged in the bottom groove 510, one end of the connecting spring 512 is connected to the inner wall of the bottom groove 510, and the other end of the connecting spring 512 is connected to the connecting rod 511.

[0032] The connecting elbow 3 is bent at ninety degrees.

[0033] Embodiment 2: The difference between this embodiment and embodiment 1 is that the inert through-tube 4 is made of inert material glass.

[0034] The inert through pipe 4 can have higher chemical stability and corrosion resistance, and will not pollute or interfere with the gas in the sample.

[0035] Embodiment 3: The difference between this embodiment and embodiment 1 is that the side surface of the fixed abutment plate 503 is in an arc shape that fits with the inertia through pipe 4 .

[0036] The fixed abutment plate 503 is elastically abutted by the abutment spring 507 to better abut and fix with the inertia passage 4 .

[0037] Embodiment 4: The difference between this embodiment and embodiment 1 is that the sealing rubber pad 509 is in a ring shape, and the inner wall of the sealing rubber pad 509 is in contact with the inert through pipe 4 .

[0038] This allows the inert through tube 4 to be better sealed under the resistance of the sealing rubber pad 509 after being inserted into the sample bottle.

[0039] In this embodiment, since there is a certain distance between the sample bottle and the SICRIT source in the olfactory injection mode of the existing SICRIT, the gas will undergo uncontrollable exchange with the air within the distance between the sample bottle and the SICRIT source, resulting in dilution of the gas sample, the stability of the medium path cannot be guaranteed, the ionization efficiency is reduced, and the reproducibility between parallel samples becomes poor.

[0040] In summary, in a specific implementation, the user first connects the inert through tube 4 to the SICRIT source 2 through the connecting elbow 3, and the SICRIT source 2 is installed on the mass spectrometer 1, and ensures that the connection is firm, and then places the sample to be analyzed at the lower end of the inert through tube 4, or extends the inert through tube 4 into a sample bottle to introduce the sample to be detected into the inert through tube 4, wherein the sample can be a gaseous sample, a liquid sample or a solid sample, and any sample containing volatile or semi-volatile substances can be detected and analyzed using the SICRIT source 2.

[0041] This design can minimize the contact between gas and air, avoid gas dilution, and ensure the concentration and stability of ionized gas. In addition, the inert tube 4 is made of inert materials such as glass, ceramic or graphite, which have high chemical stability and corrosion resistance and will not pollute or interfere with the gas in the sample.

[0042] The existence of the inert through-tube 4 is of great significance for the SICRIT analysis and detection. It can focus the gas, prevent dilution, avoid contamination, and improve the accuracy of the experiment. Through the use of the inert through-tube 4, the experimenter can more accurately control and analyze the gas composition in the sample, thereby obtaining more reliable experimental results.

[0043] The bottle mouth sealing assembly 5 arranged on the inert through tube 4, wherein the movable sleeve 501 in the bottle mouth sealing assembly 5 can be stabilized on the inert through tube 4 under the elastic resistance of the resistance spring 507 to the fixed resistance plate 503. When the inert through tube 4 is inserted into the sample bottle, the user slides the movable sleeve 501 so that the sealing rubber pad 509 arranged at the bottom end of the movable sleeve 501 can seal the sample bottle mouth, thereby reducing the escape of the sample, reducing the loss of the sample, and improving the subsequent continuous use rate.

Claims

1. An online ionization inert pipe device, comprising a mass spectrometer (1), characterized in that: The side of the mass spectrometer (1) is connected to a SICRIT source (2), the end of the SICRIT source (2) is connected to a connecting elbow (3), the bottom of the connecting elbow (3) is connected to an inert through pipe (4), and a bottle mouth sealing component (5) for sealing is slidably provided on the inert through pipe (4); The bottle mouth sealing assembly (5) comprises a movable sleeve (501) sleeved on the inert through pipe (4), two inner cavity grooves (502) are symmetrically provided on both sides of the inner wall of the movable sleeve (501), a fixed abutment plate (503) is slidably provided in the inner cavity groove (502), two pulling through holes (504) are symmetrically provided on the inner wall of the inner cavity groove (502), and a abutment push rod (505) is slidably inserted in the pulling through hole (504). The end of the resistance push rod (505) is connected to the side wall of the fixed resistance plate (503), and the ends of the two resistance push rods (505) are connected via an external connecting plate (506). A resistance spring (507) is sleeved on the resistance push rod (505), one end of the resistance spring (507) is connected to the external connecting plate (506), and the other end of the resistance spring (507) is connected to the outer wall of the movable sleeve (501).

2. The online ionization inert pipe-passing device according to claim 1, characterized in that: A bottom annular groove (508) is provided at the bottom end of the movable sleeve (501), a sealing rubber pad (509) is provided below the bottom annular groove (508), two bottom grooves (510) are symmetrically provided on the inner wall of the bottom annular groove (508), the top end of the sealing rubber pad (509) is slidably inserted into the bottom groove (510) through a connecting rod (511), a connecting spring (512) is provided in the bottom groove (510), one end of the connecting spring (512) is connected to the inner wall of the bottom groove (510), and the other end of the connecting spring (512) is connected to the connecting rod (511).

3. The online ionization inert pipe device according to claim 2, characterized in that: The connecting elbow (3) is bent at ninety degrees.

4. The online ionization inert pipe-passing device according to claim 3, characterized in that: The inert through pipe (4) is made of inert material glass.

5. The online ionization inert pipe device according to claim 4, characterized in that: The side surface of the fixed abutment plate (503) is in an arc shape that fits the inertia passage (4).

6. The on-line ionization inert pipe device according to claim 5, characterized in that: The sealing rubber pad (509) is in the shape of a ring, and the inner wall of the sealing rubber pad (509) is in contact with the inert through pipe (4).

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