Tissue cell extractor
By designing the tissue cell extractor for extruding components and installing components, the problems of inaccurate cell secting position and poor device stability are solved, and high accuracy and high stability of cell extraction is achieved, which improves cell purity and reliability of analysis. sex.
Patent Information
- Application Number
- CN202420364733.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-02-27
- Publication Date
- 2024-12-13
- Estimated Expiration
- 2034-02-27
AI Technical Summary
The existing tissue cell extractors have inaccurate cell positions during the slitting process, large slitting errors, resulting in serious mechanical damage, poor device stability, and prone to accidental pouring, affecting subsequent analysis and processing.
Designed a tissue cell extractor that includes extrusion components and mounting components to ensure accurate position of cells during slitting and reduce mechanical damage; provide stable support through installation components to prevent device dumping, and set up a filter to improve Cell purity.
Improves the accuracy and cell integrity of cell slitting, enhances the stability of the device, simplifies subsequent analysis and processing, and improves cell purity.
Smart Images

Figure CN222155667U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of cell extraction, and in particular to a tissue cell extractor. Background Art
[0002] The essence of tumor cells is the tumor; tumor tissue is composed of two parts: the substance and the stroma. The tumor substance is the tumor cell, which is the main component of the tumor and has tissue-origin specificity. The tumor stroma is the other components of the tumor tissue besides the tumor cells, mainly connective tissue and blood vessels, and some also have lymphatic vessels and nerves. In order to further study tissue cells, we usually mince and extract tissue cells for cell experimental research.
[0003] During the use of the existing tissue cell extractor, the cells are not accurately positioned during cutting, the cutting error is large, the mechanical damage to the tissue cells is large, and it is not convenient for subsequent analysis and processing; and during the operation, the device is prone to accidental tipping and has poor stability. Therefore, a tissue cell extractor is proposed to solve the above problems. Summary of the invention
[0004] In this embodiment, a tissue cell extractor is provided to solve the problems of inaccurate cell position during cutting, large cutting errors, large mechanical damage to tissue cells, and inconvenience for subsequent analysis and processing during use of existing tissue cell extractors; and the device is prone to accidental tipping over and has poor stability during operation.
[0005] According to one aspect of the present application, a tissue cell extractor is provided, comprising an extraction cylinder and a base, wherein an extrusion assembly is arranged at the top end of the extraction cylinder, wherein the extrusion assembly comprises a fixed cylinder, a movable cylinder, a threaded rod and an extrusion plate, wherein a fixed cylinder is fixedly installed on the extraction cylinder, wherein a threaded rod is rotatably connected to the interior of the fixed cylinder via a bearing, wherein a handwheel is fixedly installed at the top end of the threaded rod, wherein the bottom end of the threaded rod is threadedly connected to the movable cylinder, and the bottom end of the movable cylinder extends to the inner cavity of the extraction cylinder and is fixedly installed with an extrusion plate.
[0006] Furthermore, two guide grooves are provided on the inner wall of the fixed cylinder, and guide blocks are fixedly installed on the left and right sides of the movable cylinder, and the two guide blocks are respectively slidably connected to the two guide grooves.
[0007] Furthermore, a cleaning brush is arranged on the periphery of the extrusion plate.
[0008] Furthermore, the internal thread of the extraction cylinder is connected with a cutting seat.
[0009] Furthermore, a movable cylinder is threadedly connected to the outer surface of the extraction cylinder, a filter screen is fixedly installed inside the movable cylinder, and a discharge port is provided at the bottom end of the movable cylinder.
[0010] Furthermore, mounting plates are fixedly mounted on both the left and right sides of the extraction cylinder, and plug-in grooves are formed at the top ends of the two mounting plates.
[0011] Furthermore, two support rods are fixedly mounted on the top of the base, and mounting seats are fixedly mounted on the tops of the two support rods.
[0012] Furthermore, one side of the two mounting seats is provided with a positioning groove, and the two positioning grooves can be plugged into the two mounting plates respectively.
[0013] Furthermore, the interior of the two mounting seats are each provided with a mounting assembly, and the mounting assembly includes a connecting plate, a fixing rod, a spring and a plug-in rod. The inner cavity of the mounting seat is provided with a mounting groove, and the inner cavity of the mounting groove is slidably connected with a connecting plate, and the two ends of the connecting plate are respectively fixedly installed with a fixing rod and a plug-in rod, and the outer surface of the fixing rod is sleeved with a spring, and the top end of the fixing rod extends to the outer end of the mounting seat and is fixedly installed with a pull plate, and the plug-in rod is plugged into the plug-in groove.
[0014] Furthermore, two ends of the spring are fixedly connected to one side of the connecting plate and the inner wall of the mounting groove respectively.
[0015] Through the above-mentioned embodiments of the present application, by setting up an extrusion component and turning the hand wheel to squeeze the tissue cells into the cutting seat, it is possible to ensure that the cells are accurately positioned during cutting, reduce cutting errors, and improve cutting accuracy. At the same time, it is possible to reduce mechanical damage to tissue cells, protect the integrity of tissue cells, and facilitate subsequent analysis and processing; by setting up an installation component, pulling the pull plate, and plugging the plug rod into the plug slot, not only can a stable support be provided to prevent the device from accidentally tipping over during operation, thereby enhancing the stability of the device, but also facilitating transportation and storage. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.
[0017] Figure 1 This is a schematic diagram of the overall three-dimensional structure of an embodiment of the present application;
[0018] Figure 2 This is a schematic diagram of the overall internal structure of an embodiment of the present application;
[0019] Figure 3 For an embodiment of the present application Figure 2 A is an enlarged structural diagram of FIG.
[0020] In the figure: 1. extraction cylinder; 2. moving cylinder; 3. threaded rod; 4. guide block; 5. hand wheel; 6. fixed cylinder; 7. guide groove; 8. extrusion plate; 9. mounting plate; 10. mounting seat; 11. movable cylinder; 12. filter screen; 13. discharge port; 14. base; 15. support rod; 16. cutting seat; 17. cleaning brush; 18. plug-in rod; 19. spring; 20. pull plate; 21. fixed rod; 22. connecting plate; 23. plug-in groove; 24. positioning groove. DETAILED DESCRIPTION
[0021] In order to enable those skilled in the art to better understand the solution of the present application, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work should fall within the scope of protection of the present application.
[0022] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchanged where appropriate, so that the embodiments of the present application described here. In addition, the terms "including" and "having" and any of their variations are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units that are clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.
[0023] In the present application, the terms "upper", "lower", "left", "right", "front", "back", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings. These terms are mainly used to better describe the present application and its embodiments, and are not used to limit the indicated devices, elements or components to have a specific orientation, or to be constructed and operated in a specific orientation.
[0024] In addition, some of the above terms may be used to express other meanings in addition to indicating orientation or positional relationship. For example, the term "on" may also be used to express a certain dependency or connection relationship in some cases. For those of ordinary skill in the art, the specific meanings of these terms in this application can be understood according to specific circumstances.
[0025] In addition, the terms "installed", "set", "provided with", "connected", "connected", and "socketed" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection, or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be an internal connection between two devices, elements, or components. For those of ordinary skill in the art, the specific meanings of the above terms in this application can be understood according to specific circumstances.
[0026] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present application will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.
[0027] See also Figure 1-3 As shown, a tissue cell extractor comprises an extraction cylinder 1 and a base 14, wherein an extrusion assembly is arranged at the top of the extraction cylinder 1, wherein the extrusion assembly comprises a fixed cylinder 6, a movable cylinder 2, a threaded rod 3 and an extrusion plate 8, wherein the fixed cylinder 6 is fixedly installed on the extraction cylinder 1, wherein the fixed cylinder 6 is rotatably connected to the threaded rod 3 via a bearing, wherein a hand wheel 5 is fixedly installed at the top of the threaded rod 3, wherein the bottom end of the threaded rod 3 is threadedly connected to the movable cylinder 2, and the bottom end of the movable cylinder 2 extends to the inner cavity of the extraction cylinder 1 and is fixedly installed with an extrusion plate 8.
[0028] The inner wall of the fixed cylinder 6 is provided with two guide grooves 7 , and the left and right sides of the movable cylinder 2 are fixedly mounted with guide blocks 4 , and the two guide blocks 4 are slidably connected to the two guide grooves 7 , respectively.
[0029] A cleaning brush 17 is disposed on the periphery of the extrusion plate 8 .
[0030] The internal thread of the extraction cylinder 1 is connected with a cutting seat 16 .
[0031] The outer surface of the extraction cylinder 1 is threadedly connected with a movable cylinder 11 , a filter screen 12 is fixedly installed inside the movable cylinder 11 , and a discharge port 13 is opened at the bottom end of the movable cylinder 11 .
[0032] Mounting plates 9 are fixedly mounted on both the left and right sides of the extraction cylinder 1 , and plug-in slots 23 are formed at the top ends of the two mounting plates 9 .
[0033] Two support rods 15 are fixedly mounted on the top of the base 14 , and a mounting seat 10 is fixedly mounted on the top of the two support rods 15 .
[0034] A positioning groove 24 is formed on one side of the two mounting seats 10 , and the two positioning grooves 24 can be plugged into the two mounting plates 9 respectively.
[0035] The two mounting seats 10 are each provided with a mounting assembly, and the mounting assembly includes a connecting plate 22, a fixing rod 21, a spring 19 and a plug-in rod 18. The inner cavity of the mounting seat 10 is provided with a mounting groove, and the inner cavity of the mounting groove is slidably connected with a connecting plate 22. The two ends of the connecting plate 22 are respectively fixedly installed with a fixing rod 21 and a plug-in rod 18. The outer surface of the fixing rod 21 is sleeved with a spring 19. The top end of the fixing rod 21 extends to the outer end of the mounting seat 10 and is fixedly installed with a pull plate 20, and the plug-in rod 18 is plugged into the plug-in groove 23.
[0036] The two ends of the spring 19 are fixedly connected to one side of the connecting plate 22 and the inner wall of the mounting groove respectively.
[0037] When the present application is in use, the tissue cells are placed inside the extraction tube 1, and then according to the precision of the tissue cell cutting, the cutting seat 16 with different cutting precisions is used, the cutting seat 16 is rotated so that the cutting seat 16 is threadedly connected to the extraction tube 1, and then the movable tube 11 is threadedly connected to the extraction tube 1, and the hand wheel 5 is rotated. The rotation of the hand wheel 5 drives the threaded rod 3 to rotate. Under the action of the guide groove 7 and the guide block 4, the threaded rod 3 rotates to drive the movable tube 2 to move up and down, and the tissue cells are squeezed into the cutting seat 16, which can ensure that the cells are accurately positioned during cutting, reduce cutting errors, and improve cutting accuracy. At the same time, it can reduce mechanical damage to tissue cells, protect the integrity of tissue cells, and facilitate subsequent analysis and processing. ; By setting the filter net 12, the filter net 12 can remove impurities, necrotic cells and cell fragments in the cut tissue cells, improve the cell purity, and make the experimental results more accurate and reliable; pull the pull plate 20, the pull plate 20 drives the connecting plate 22 to slide inside the installation groove, the fixing rod 21 drives the connecting plate 22 to move respectively, and the connecting plate 22 drives the spring 19 to compress respectively, and the plug-in rod 18 is plugged into the plug-in slot 23, which can not only provide a stable support to prevent the device from accidentally tipping over during operation, enhance the stability of the device, but also facilitate transportation and storage; by setting a cleaning brush, the inner wall of the extraction cylinder can be cleaned after the tissue cells are completed in advance to avoid the inner wall being contaminated with residues and affecting the next use effect.
[0038] The benefits of this application are:
[0039] 1. By setting an extrusion component, rotating the hand wheel 5, the hand wheel 5 rotates to drive the threaded rod 3 to rotate. Under the action of the guide groove 7 and the guide block 4, the threaded rod 3 rotates to drive the moving cylinder 2 to move up and down, and the tissue cells are squeezed into the cutting seat 16, which can ensure that the cells are accurately positioned during cutting, reduce cutting errors, and improve cutting accuracy. At the same time, it can reduce mechanical damage to tissue cells, protect the integrity of tissue cells, and facilitate subsequent analysis and processing;
[0040] 2. By setting up the installation assembly, pull the pull plate 20, the pull plate 20 drives the connecting plate 22 to slide inside the installation groove, the fixing rod 21 drives the connecting plate 22 to move, the connecting plate 22 drives the spring 19 to compress, and the plug-in rod 18 is plugged into the plug-in groove 23, which can not only provide a stable support to prevent the device from accidentally tipping over during operation, enhance the stability of the device, but also facilitate transportation and storage.
[0041] 3. By setting the filter 12, the filter 12 can remove impurities, necrotic cells and cell fragments in the cut tissue cells, improve the cell purity, and make the experimental results more accurate and reliable.
[0042] The above description is only the preferred embodiment of the present application and is not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims
1. A tissue cell extractor, comprising an extraction tube (1) and a base (14), characterized in that: The top end of the extraction cylinder (1) is provided with an extrusion assembly, which comprises a fixed cylinder (6), a movable cylinder (2), a threaded rod (3) and an extrusion plate (8). The fixed cylinder (6) is fixedly mounted on the extraction cylinder (1), the interior of the fixed cylinder (6) is rotatably connected to the threaded rod (3) via a bearing, a hand wheel (5) is fixedly mounted on the top end of the threaded rod (3), the bottom end of the threaded rod (3) is threadedly connected to the movable cylinder (2), and the bottom end of the movable cylinder (2) extends to the inner cavity of the extraction cylinder (1) and is fixedly mounted with the extrusion plate (8).
2. The tissue cell extractor according to claim 1, characterized in that: The inner wall of the fixed cylinder (6) is provided with two guide grooves (7), and the left and right sides of the movable cylinder (2) are fixedly mounted with guide blocks (4), and the two guide blocks (4) are respectively slidably connected to the two guide grooves (7).
3. The tissue cell extractor according to claim 1, characterized in that: A cleaning brush (17) is arranged on the periphery of the extrusion plate (8).
4. The tissue cell extractor according to claim 1, characterized in that: The internal thread of the extraction cylinder (1) is connected with a cutting seat (16).
5. The tissue cell extractor according to claim 1, characterized in that: The outer surface of the extraction cylinder (1) is threadedly connected to a movable cylinder (11), a filter screen (12) is fixedly installed inside the movable cylinder (11), and a discharge port (13) is provided at the bottom end of the movable cylinder (11).
6. The tissue cell extractor according to claim 1, characterized in that: Mounting plates (9) are fixedly mounted on both the left and right sides of the extraction cylinder (1), and plug-in slots (23) are provided at the top ends of the two mounting plates (9).
7. The tissue cell extractor according to claim 1, characterized in that: Two support rods (15) are fixedly mounted on the top of the base (14), and mounting seats (10) are fixedly mounted on the tops of the two support rods (15).
8. The tissue cell extractor according to claim 7, characterized in that: One side of the two mounting seats (10) is provided with a positioning groove (24), and the two positioning grooves (24) can be plugged into the two mounting plates (9) respectively.
9. The tissue cell extractor according to claim 7, characterized in that: The two mounting seats (10) are each provided with a mounting assembly, the mounting assembly comprising a connecting plate (22), a fixing rod (21), a spring (19) and a plug-in rod (18); the inner cavity of the mounting seat (10) is provided with a mounting groove, the inner cavity of the mounting groove is slidably connected with a connecting plate (22), the two ends of the connecting plate (22) are respectively fixedly mounted with a fixing rod (21) and a plug-in rod (18), the outer surface of the fixing rod (21) is sleeved with a spring (19), the top end of the fixing rod (21) extends to the outer end of the mounting seat (10) and is fixedly mounted with a pull plate (20), and the plug-in rod (18) is plugged into the plug-in groove (23).
10. The tissue cell extractor according to claim 9, characterized in that: The two ends of the spring (19) are respectively fixedly connected to one side of the connecting plate (22) and the inner wall of the mounting groove.
