Device for preparing long-acting antibody diluent

By designing a device for guide tube, mixing box, quantitative assembly and mixing assembly, the problem of irregular amount of reagent addition in the prior art is solved, and efficient preparation and concentration accuracy of long-acting antibody diluents are achieved.

CN222287033UActive Publication Date: 2025-01-03ZHONGRONGDA BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202421083604.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-17
Publication Date
2025-01-03
Estimated Expiration
2034-05-17

AI Technical Summary

Technical Problem

When preparing long-acting antibody dilutions, it is difficult to quantify the amount of reagent added, resulting in reduced preparation efficiency and incorrect concentration.

Method used

A device including a guide tube, a mixing box, a metering assembly and a mixing assembly is designed to achieve quantitative addition of reagents through the adjustment screw of the metering assembly and a contactless liquid level sensor, and mix it through a stirring rod driven by a power motor to ensure that Even mixing of reagents.

Benefits of technology

Quantitative addition and uniform mixing of reagents are achieved, the preparation efficiency of long-acting antibody dilution is improved, and the accuracy of concentration is ensured.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a device for preparing a long-acting antibody diluent, which belongs to the technical field of preparation devices, and adopts the technical scheme that the device comprises a guide pipe, one end of the guide pipe is communicated with a mixing box, the other end of the guide pipe is communicated with a quantifying assembly, and the top of the mixing box is fixedly connected with a mixing assembly; the quantitative assembly comprises a square box, the left side and the right side of the square box communicate with the opposite ends of the guide pipes, a cross-shaped groove is formed in the front side of the square box, adjusting screw rods are rotationally connected to the top and the bottom of the inner wall of the cross-shaped groove, and cross-shaped blocks are rotationally connected to the surfaces of the adjusting screw rods. The problems that when an existing preparation device is used for preparing the long-acting antibody diluent, most of the existing preparation devices are not convenient to quantify the reagent adding amount during preparation, so that the preparation efficiency of the long-acting antibody diluent is reduced, and when the reagent adding amount is not accurate, the concentration of the long-acting antibody diluent is likely to be wrong are solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of preparation devices, in particular to a device for preparing a long-acting antibody diluent. Background Art

[0002] Long-acting antibody diluent is a solution used in the laboratory to dilute antibodies to achieve an appropriate concentration for immunostaining, immunoassay and other related experiments. Antibodies are proteins produced by the immune system that have the ability to specifically bind to antigens.

[0003] When preparing a long-acting antibody diluent, a preparation device is used, and a device for preparing a long-acting antibody diluent is one of them. However, when preparing a long-acting antibody diluent, most of the existing preparation devices are not convenient for quantifying the amount of reagent added during preparation, which leads to a decrease in the preparation efficiency of the long-acting antibody diluent. When the amount of reagent added is inaccurate, the concentration of the long-acting antibody diluent is easily incorrect. Therefore, a device for preparing a long-acting antibody diluent is proposed. Utility Model Content

[0004] The utility model provides a device for preparing a long-acting antibody diluent, aiming to solve the problem that most of the existing preparation devices are inconvenient to quantify the amount of reagent added during the preparation of the long-acting antibody diluent, thereby reducing the preparation efficiency of the long-acting antibody diluent, and when the amount of reagent added is inaccurate, it is easy to cause the concentration of the long-acting antibody diluent to be wrong.

[0005] The utility model is implemented as follows: a device for preparing a long-acting antibody diluent comprises a guide tube, one end of the guide tube is connected to a mixing box, the other end of the guide tube is connected to a quantitative component, and the top of the mixing box is fixedly connected to the mixing component;

[0006] The quantitative component includes a square box, the left and right sides of the square box are connected to the end opposite to the guide tube, a cross-shaped groove is opened on the front side of the square box, the top and bottom of the inner wall of the cross-shaped groove are rotatably connected with an adjusting screw, the surface of the adjusting screw is rotatably connected with a cross-shaped block, the surface of the cross-shaped block is slidably connected to the inner wall of the cross-shaped groove, a non-contact liquid level sensor is fixedly connected to the front side of the cross-shaped block, a buzzer is fixedly connected to the top of the non-contact liquid level sensor, and a quantitative scale is arranged on the front side of the square box.

[0007] In order to achieve the effect of mixing the reagents, as a preferred device for preparing a long-acting antibody dilution solution of the utility model, the mixing assembly includes a fixed block, the bottom of the fixed block is fixedly connected to the top of the mixing box, the top of the fixed block is fixedly connected to the bottom of the square box, the bottom of the fixed block is provided with a mounting hole, the inner wall of the mounting hole is fixedly connected to a power motor, the output end of the power motor is fixedly connected to a fixing rod, the bottom of the fixing rod is rotatably connected to the bottom of the inner wall of the mixing box, and the surface of the fixed rod is fixedly connected to a stirring rod.

[0008] In order to control the flow rate and opening and closing of the guide tube and protect the valve, as a preferred device for preparing a long-acting antibody dilution solution of the utility model, a valve is provided on the surface of the guide tube close to one end of the square box, and there are three valves in total, and a protective sleeve used in conjunction with the valve is fixedly connected to the surface of the valve.

[0009] In order to discharge the mixed reagents in the mixing box, as a preferred device for preparing a long-acting antibody diluent of the utility model, the front side of the mixing box is connected to a discharge pipe, and the end of the discharge pipe away from the mixing box is connected to another valve.

[0010] In order to assist in guiding the installation position of the tempered glass and observe the amount of reagent added, as a preferred device for preparing a long-acting antibody dilution solution of the utility model, a square groove is opened on the front side of the square box, the inner wall of the square groove is fixedly connected to the tempered glass, and the position of the square groove is on the left side of the quantitative scale.

[0011] In order to facilitate the user to observe the required amount, as a preferred device for preparing a long-acting antibody diluent of the utility model, the front side of the non-contact liquid level sensor is fixedly connected to a pointer used therewith, and the pointer is set to be conical.

[0012] In order to improve the convenience of rotating the adjusting screw, as a preferred device for preparing a long-acting antibody dilution solution of the utility model, the top of the square box is rotatably connected to a ring block, the bottom of the ring block passes through the top of the square box and is fixedly connected to one end of the adjusting screw.

[0013] In order to increase the moving stability of the cross block and assist in guiding the installation position, as a preferred device for preparing a long-acting antibody dilution of the utility model, a threaded hole is opened on the top of the cross block, and the inner wall of the threaded hole contacts the surface of the adjusting screw.

[0014] Compared with the prior art, the beneficial effects of the utility model are:

[0015] The device for preparing a long-acting antibody diluent is provided with a guide tube, a mixing box, a quantitative component and a mixing component. The quantitative component can be rotated to move the quantitative component upward or downward. Then, when the quantitative component stays at a desired position, a reagent is added into the quantitative component. When the liquid level of the added reagent reaches the position of the set quantitative component through the sensing of the quantitative component to the liquid, the quantitative component can issue a prompt and then stop adding the reagent, thereby achieving quantitative addition of the reagent. Subsequently, the added reagent can be transported into the mixing box through the guidance of the guide tube, and by starting the mixing component, the mixing component can be fixed by the mixing box to stir and mix the reagent transported into the interior, thereby achieving preparation of the long-acting antibody diluent. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is an overall structural diagram of the device for preparing a long-acting antibody diluent of the utility model;

[0017] Figure 2 It is a cross-sectional view of the mixing box in the utility model;

[0018] Figure 3 This is a schematic diagram of the connection between the guide pipe and the mixing box in the utility model;

[0019] Figure 4 It is a structural schematic diagram of the mixing component in the utility model;

[0020] Figure 5 For this utility model Figure 2 Enlarged view of point A in .

[0021] In the figure, 1. guide tube; 2. mixing box; 3. quantitative component; 301. square box; 302. cross groove; 303. adjusting screw; 304. cross block; 305. non-contact liquid level sensor; 306. buzzer; 307. quantitative scale; 4. mixing component; 401. fixing block; 402. mounting hole; 403. power motor; 404. fixing rod; 405. stirring rod; 5. valve; 6. protective cover; 7. discharge pipe; 8. square groove; 9. tempered glass; 10. pointer; 11. ring block; 12. threaded hole. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the utility model more clear, the utility model is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.

[0023] In the description of the present invention, it should be understood that the terms "length", "width", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In addition, in the description of the present invention, "multiple" means two or more, unless otherwise clearly and specifically defined.

[0024] See also Figure 1-5 The utility model provides a technical solution: a device for preparing a long-acting antibody diluent, comprising a guide tube 1, one end of the guide tube 1 is connected to a mixing box 2, the other end of the guide tube 1 is connected to a quantitative component 3, and the top of the mixing box 2 is fixedly connected to a mixing component 4;

[0025] The quantitative component 3 includes a square box 301, the left and right sides of the square box 301 are connected to the end opposite to the guide tube 1, a cross-shaped groove 302 is provided on the front side of the square box 301, the top and bottom of the inner wall of the cross-shaped groove 302 are rotatably connected with an adjusting screw 303, the surface of the adjusting screw 303 is rotatably connected with a cross-shaped block 304, the surface of the cross-shaped block 304 is slidably connected to the inner wall of the cross-shaped groove 302, a non-contact liquid level sensor 305 is fixedly connected to the front side of the cross-shaped block 304, a buzzer 306 is fixedly connected to the top of the non-contact liquid level sensor 305, and a quantitative scale 307 is provided on the front side of the square box 301.

[0026] In this embodiment: by setting the guide tube 1, the mixing box 2, the quantitative component 3 and the mixing component 4, the quantitative component 3 can be rotated to move the quantitative component 3 upward or downward, and then when the quantitative component 3 stays at the desired position, the reagent is added to the quantitative component 3, and through the sensing of the liquid by the quantitative component 3, when the liquid level of the added reagent reaches the set position of the quantitative component 3, the quantitative component 3 can issue a prompt, and then stop adding the reagent, thereby achieving the quantitative addition of the reagent, and then through the guidance of the guide tube 1, the added reagent can be transported to the mixing box 2, and by starting the mixing component 4, the mixing component 4 can be fixed by the mixing box 2 to stir and mix the reagent transported to the inside, thereby achieving the preparation of the long-acting antibody dilution solution.

[0027] As a technical optimization solution of the utility model, the mixing component 4 includes a fixed block 401, the bottom of the fixed block 401 is fixedly connected to the top of the mixing box 2, the top of the fixed block 401 is fixedly connected to the bottom of the square box 301, the bottom of the fixed block 401 is provided with a mounting hole 402, the inner wall of the mounting hole 402 is fixedly connected to a power motor 403, the output end of the power motor 403 is fixedly connected to a fixed rod 404, the bottom of the fixed rod 404 is rotatably connected to the bottom of the inner wall of the mixing box 2, and the surface of the fixed rod 404 is fixedly connected to a stirring rod 405.

[0028] In this embodiment: by setting up the mixing component 4, the power motor 403 can be started, and the power motor 403 can be fixed in the mounting hole 402 and the fixed block 401, driving the fixed rod 404 to rotate, and when the fixed rod 404 rotates, the stirring rod 405 can be connected with the fixed rod 404, so that the stirring rod 405 can be rotated by the fixed rod 404, so that the rotating stirring rod 405 can stir and mix the reagents.

[0029] As a technical optimization solution of the utility model, a valve 5 is provided on the surface of the guide tube 1 close to one end of the square box 301. There are three valves 5 in total, and a protective sleeve 6 used in conjunction with the valve 5 is fixedly connected to the surface of the valve 5.

[0030] In this embodiment: by providing the valve 5 and the protective sleeve 6, the valve 5 can be opened and closed to control the flow rate and opening and closing of the guide tube 1, and by connecting the protective sleeve 6 to the valve 5, the protective sleeve 6 can protect the valve 5 to prevent the reagent from contacting the valve 5 and causing corrosion to the valve 5.

[0031] As a technical optimization solution of the utility model, the front side of the mixing box 2 is connected with a discharge pipe 7 , and one end of the discharge pipe 7 away from the mixing box 2 is connected to another valve 5 .

[0032] In this embodiment, the discharge pipe 7 is provided, and the discharge pipe 7 is connected with the mixing box 2 so that the discharge pipe 7 can discharge the mixed reagents in the mixing box 2 .

[0033] As a technical optimization solution of the present invention, a square groove 8 is opened on the front side of the square box 301 , and a tempered glass 9 is fixedly connected to the inner wall of the square groove 8 , and the position of the square groove 8 is on the left side of the quantitative scale 307 .

[0034] In this embodiment: by providing the square groove 8 and the tempered glass 9, the square groove 8 can be connected with the tempered glass 9 so that the installation position of the tempered glass 9 can be assisted by the square groove 8, and the transparency of the tempered glass 9 makes it convenient for the user to observe the amount of reagent added in the square box 301.

[0035] As a technical optimization solution of the present invention, a pointer 10 used in conjunction with the non-contact liquid level sensor 305 is fixedly connected to the front side thereof, and the pointer 10 is set to be conical.

[0036] In this embodiment: by setting the pointer 10, the pointer 10 can be connected to the non-contact liquid level sensor 305, so that when the non-contact liquid level sensor 305 moves, the pointer 10 can be driven to move, and when the pointer 10 moves, it can point to the quantitative scale 307, thereby facilitating the user to observe the required amount.

[0037] As a technical optimization solution of the utility model, the top of the square box 301 is rotatably connected with an annular block 11 , the bottom of the annular block 11 passes through the top of the square box 301 and is fixedly connected to one end of the adjusting screw 303 .

[0038] In this embodiment, the annular block 11 is provided, and the annular block 11 can be connected to the adjusting screw 303, so that the user can rotate the annular block 11 to drive the adjusting screw 303 to rotate, thereby improving the convenience of rotating the adjusting screw 303.

[0039] As a technical optimization solution of the present invention, a threaded hole 12 is opened on the top of the cross-shaped block 304 , and the inner wall of the threaded hole 12 contacts the surface of the adjusting screw 303 .

[0040] In this embodiment: by setting the threaded hole 12, the contact between the threaded hole 12 and the adjusting screw 303 can increase the movement stability of the cross block 304 through the cooperation between the threaded hole 12 and the adjusting screw 303, and the contact between the threaded hole 12 and the adjusting screw 303 can assist in guiding the installation position of the cross block 304.

[0041] Working principle: First, the adjusting screw 303 is rotated, so that the adjusting screw 303 can drive the cross block 304 to move, and the cross groove 302 is limited to prevent the moving position of the cross block 304 from being offset. Then, the cross block 304 is connected to the non-contact liquid level sensor 305, so that when the cross block 304 moves, the non-contact liquid level sensor 305 can be driven to move. Then, the non-contact liquid level sensor 305 is connected to the pointer 10, so that when the non-contact liquid level sensor 305 moves, the pointer 10 can be driven to point to the desired quantitative scale 307. Then, when the liquid level of the added reagent reaches the quantitative scale 307 pointed to by the pointer 10, The non-contact liquid level sensor 305 can issue a prompt through the buzzer 306, so that the quantitative addition of the reagent can be achieved, and then the guide tube 1 is opened through the valve 5, so that the guide tube 1 can transport the quantitative reagent to the mixing box 2, and then the power motor 403 is started, and the power motor 403 can be fixed in the mounting hole 402 and the fixed block 401 to drive the fixed rod 404 to rotate, and when the fixed rod 404 rotates, the stirring rod 405 can be connected with the fixed rod 404, so that the stirring rod 405 is driven by the fixed rod 404 to rotate, so that the rotating stirring rod 405 can stir and mix the reagent, and then until the mixing of the reagent is completed.

[0042] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A device for preparing a long-acting antibody dilution, comprising a guide tube (1), characterized in that: One end of the guide tube (1) is connected to a mixing box (2), the other end of the guide tube (1) is connected to a dosing component (3), and the top of the mixing box (2) is fixedly connected to a mixing component (4); The quantitative component (3) comprises a square box (301), the left and right sides of the square box (301) being connected to an end opposite to the guide tube (1), a cross-shaped groove (302) being provided on the front side of the square box (301), the top and bottom of the inner wall of the cross-shaped groove (302) being rotatably connected to an adjusting screw (303), the surface of the adjusting screw (303) being rotatably connected to a cross-shaped block (304), the surface of the cross-shaped block (304) being slidably connected to the inner wall of the cross-shaped groove (302), a non-contact liquid level sensor (305) being fixedly connected to the front side of the cross-shaped block (304), a buzzer (306) being fixedly connected to the top of the non-contact liquid level sensor (305), and a quantitative scale (307) being provided on the front side of the square box (301).

2. A device for preparing a long-acting antibody dilution according to claim 1, characterized in that: The mixing assembly (4) comprises a fixed block (401), the bottom of the fixed block (401) is fixedly connected to the top of the mixing box (2), the top of the fixed block (401) is fixedly connected to the bottom of the square box (301), the bottom of the fixed block (401) is provided with a mounting hole (402), the inner wall of the mounting hole (402) is fixedly connected to a power motor (403), the output end of the power motor (403) is fixedly connected to a fixed rod (404), the bottom of the fixed rod (404) is rotatably connected to the bottom of the inner wall of the mixing box (2), and the surface of the fixed rod (404) is fixedly connected to a stirring rod (405).

3. A device for preparing a long-acting antibody dilution according to claim 1, characterized in that: A valve (5) is provided on the surface of one end of the guide tube (1) close to the square box (301), wherein three valves (5) are provided in total, and a protective sleeve (6) used in conjunction with the valve (5) is fixedly connected to the surface of the valve (5).

4. A device for preparing a long-acting antibody dilution according to claim 1, characterized in that: The front side of the mixing box (2) is connected to a discharge pipe (7), and one end of the discharge pipe (7) away from the mixing box (2) is connected to another valve (5).

5. The device for preparing a long-acting antibody dilution according to claim 1, characterized in that: A square groove (8) is provided on the front side of the square box (301), and a tempered glass (9) is fixedly connected to the inner wall of the square groove (8), and the position of the square groove (8) is located on the left side of the quantitative scale (307).

6. The device for preparing a long-acting antibody diluent according to claim 1, characterized in that: A pointer (10) for use with the non-contact liquid level sensor (305) is fixedly connected to the front side thereof, and the pointer (10) is configured to be conical.

7. The device for preparing a long-acting antibody dilution according to claim 1, characterized in that: The top of the square box (301) is rotatably connected to an annular block (11), and the bottom of the annular block (11) passes through the top of the square box (301) and is fixedly connected to one end of the adjusting screw (303).

8. The device for preparing a long-acting antibody diluent according to claim 1, characterized in that: A threaded hole (12) is formed at the top of the cross-shaped block (304), and the inner wall of the threaded hole (12) contacts the surface of the adjusting screw (303).