Sample detection device

Abstract

The utility model discloses a sample detection device. The sample detection device comprises a reaction assembly, a reagent storage assembly and a sensor, the reaction assembly is used for preparing a to-be-detected sample; the reagent storage assembly is connected with the reaction assembly through a reagent pipeline, and the reagent storage assembly is used for storing a reagent required by detection; the sensor is used for detecting the reagent state of the reagent storage assembly, and the sensor is arranged on the reagent pipeline between the reaction assembly and the reagent storage assembly; the reagent pipeline between the reaction assembly and the sensor is a first pipeline, the reagent pipeline between the sensor and the reagent storage assembly is a second pipeline, and the volume of the first pipeline is smaller than that of the second pipeline. By means of the mode, when the reagent in the reagent storage assembly of the sample detection device is replaced, the amount of the residual reagent in the first pipeline is small, the discarding amount of the reagent in the first pipeline can be reduced, the situation of reagent waste is reduced, and the use efficiency of the reagent is improved.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a sample detection device. Background Art

[0002] Existing sample detection devices are usually provided with a reaction component and a reagent storage component. The reagent storage component is used to add the stored reagent to the reaction component. The sample detection device prepares the sample to be tested through the reaction component and transfers the sample to be tested to the detection component to obtain the test results of multiple parameters.

[0003] In order to timely reflect the reagent status of the reagent storage component, a sensor is usually set in the machine to detect the reagent status of the pipeline. Existing sample detection devices usually set the distance between the sensor and the reaction component to be farther, and the distance between the sensor and the reagent storage mechanism to be closer, so as to reduce the impact of the sensor on other components in the machine. When the sensor detects that there is no reagent in the pipeline between the reagent storage mechanism and the sensor, the sensor triggers an alarm and allows the user to replace the reagent in the reagent storage mechanism. After the reagent is replaced, in order to discharge the bubbles in the pipeline, the reagent remaining in the pipeline between the sensor and the reaction component needs to be emptied and discarded, resulting in a waste of reagents and a low utilization rate of the reagents. Utility Model Content

[0004] In order to solve the problems of large amount of reagent discard and low reagent utilization rate in the prior art, the present application provides a sample detection device.

[0005] In order to solve the technical problems existing in the prior art, the present application provides a sample detection device, including a reaction component, a reagent storage component and a sensor. The reaction component is used to prepare a sample to be tested; the reagent storage component is connected to the reaction component through a reagent pipeline, and the reagent storage component is used to store the reagent required for detection; the sensor is used to detect the reagent state of the reagent storage component, and the sensor is arranged on the reagent pipeline between the reaction component and the reagent storage component; wherein the reagent pipeline between the reaction component and the sensor is a first pipeline, and the reagent pipeline between the sensor and the reagent storage component is a second pipeline, and the volume of the first pipeline is smaller than the volume of the second pipeline.

[0006] Optionally, the sample detection device also includes a sample adding component, which is used to add the original sample to the reaction component, and the reagent storage component is used to transfer the third volume of reagent to the reaction component under the action of a driving force, so that the original sample reacts with the reagent and prepares a sample to be tested; wherein the volume of the first pipeline is greater than or equal to the third volume.

[0007] Optionally, the sample detection device also includes a pipetting component, a first connecting end of the pipetting component is connected to the reagent storage component through a second pipeline, and a second connecting end of the pipetting component is connected to the reaction component through the first pipeline. The pipetting component is used to provide driving force for the reagent in the reagent storage component to add the reagent in the reagent pipeline to the reaction component.

[0008] Optionally, the volume of the second pipeline is greater than or equal to twice the third volume.

[0009] Optionally, the sensor includes a transmitter and a receiver, the transmitter and the receiver are respectively located on both sides of the reagent pipeline, and the transmitter is used to transmit a detection signal to the reagent pipeline.

[0010] Optionally, the sample detection device further includes a detection component, which is connected to the reaction component via a sample pipeline, the reaction component is used to transfer the sample to be tested to the detection component via the sample pipeline, and the detection component is used to detect the sample to be tested.

[0011] Optionally, the reaction component includes a first reaction pool and a second reaction pool, and the reagent storage component includes a first storage mechanism and a second storage mechanism for storing different reagents, the first connection end of the first storage mechanism is connected to the first connection end of the first reaction pool through a pipeline, the second connection end of the first storage mechanism is connected to the first connection end of the second reaction pool through a pipeline, and the second storage mechanism is connected to the first connection end or the second connection end of the second reaction pool through a pipeline.

[0012] Optionally, the detection component is used to perform a first test item on the first sample to be tested in the first reaction pool and the second reaction pool, or, the detection component is used to perform a first test item on the first sample to be tested in the first reaction pool and perform a second test item on the second sample to be tested in the second reaction pool.

[0013] Optionally, the reagent storage component also includes a third storage mechanism, which is used to store diluent, the first connection end of the third storage mechanism is connected to the third connection end of the second reaction tank through a pipeline, the second connection end of the third storage mechanism is connected to the second connection end of the first reaction tank through a pipeline, and the third connection end of the third storage mechanism is connected to the detection component through a pipeline.

[0014] Optionally, the reagent storage assembly also includes an air pressure source, which is connected to the first storage mechanism and the second storage mechanism respectively, and the air pressure source is used to provide a driving force so that the reagents in the first storage mechanism or the second storage mechanism enter the second reaction tank through the pipeline.

[0015] Compared with the prior art, the sample detection device of the present application includes a reaction component, a reagent storage component and a sensor. The reaction component is used to prepare samples to be tested; the reagent storage component is connected to the reaction component through a reagent pipeline, and the reagent storage component is used to store the reagents required for detection; the sensor is used to detect the reagent status of the reagent storage component, and the sensor is arranged on the reagent pipeline between the reaction component and the reagent storage component; the reagent pipeline between the reaction component and the sensor is the first pipeline, and the reagent pipeline between the sensor and the reagent storage component is the second pipeline, and the volume of the first pipeline is smaller than the volume of the second pipeline. In the above manner, when the sample detection device of the present application replaces the reagent of the reagent storage component, the amount of reagent remaining in the first pipeline is less, which can reduce the amount of reagent discarded in the first pipeline, reduce the waste of reagents, and improve the efficiency of reagent use. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 is a structural schematic diagram of an embodiment of a sample detection device provided by the present application;

[0018] Figure 2 is a structural schematic diagram of another embodiment of the sample detection device provided by the present application;

[0019] Figure 3 yes Figure 1 Schematic diagram of the structure of the sensor;

[0020] Figure 4 It is a structural schematic diagram of another embodiment of the sample detection device provided by the present application.

[0021] In the figure, 10, reaction component; 110, first reaction pool; 120, second reaction pool; 20, reagent storage component; 210, first storage mechanism; 220, second storage mechanism; 230, third storage mechanism; 30, sensor; 31, first pipeline; 32, second pipeline; 33, transmitter; 34, receiver; 40, detection component; 50, shell. DETAILED DESCRIPTION

[0022] The present application is further described in detail below in conjunction with the accompanying drawings and examples. It is particularly noted that the following examples are only used to illustrate the present application, but are not intended to limit the scope of the present application. Similarly, the following examples are only some embodiments of the present application rather than all embodiments, and all other embodiments obtained by those of ordinary skill in the art without making creative work are within the scope of protection of the present application.

[0023] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0024] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "install", "set", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or connected through an intermediate medium. For ordinary technicians in this field, if there are directional indications (such as up, down, left, right, front, back...) involved in the embodiments of this application, the directional indications are only used to explain the relative position relationship, movement, etc. between the components in a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indications will also change accordingly.

[0025] The present application embodiment first proposes a sample detection device, see Figure 1 , Figure 1 FIG. 1 is a schematic diagram of the structure of an embodiment of a sample detection device provided by the present application. Figure 1 As shown, the sample detection device of this embodiment includes a reaction component 10 , a reagent storage component 20 and a sensor 30 .

[0026] Specifically, the reaction component 10 is used to prepare the sample to be tested. For example, the reaction component 10 may include at least one reaction pool, and the reaction pool may be configured in the shape of an opening, so that the sample detection device can directly add the original sample to the reaction component 10 through the opening. The original sample may be a blood sample obtained after the user collects the sample from the test subject, or may be a sample obtained after pre-diluting the blood sample. The original sample may include a whole blood sample, a serum sample, a venous blood sample, a trace blood sample, etc., which will not be described in detail here.

[0027] The reagent storage component 20 is connected to the reaction component 10 through a reagent pipeline, and the reagent storage component 20 is used to store the reagents required for the test. For example, the reagent storage component 20 can be used to store the diluent and hemolytic agent required for the test; when the sample detection device is used to measure the sample by fluorescent staining, the reagent storage component 20 can also be used to store the dye solution required for the test. The sensor 30 is used to detect the reagent status of the reagent storage component 20, and the reagent status is used to reflect whether there is a reagent in the reagent storage component 20 and the pipeline between the reagent storage component 20 and the sensor 30. The sensor 30 is arranged on the reagent pipeline between the reaction component 10 and the reagent storage component 20, and the first connection end of the sensor 30 is connected to the reaction component 10 through the reagent pipeline, and the second connection end of the sensor 30 is connected to the reagent storage component 20 through the reagent pipeline.

[0028] The reagent pipeline between the reaction component 10 and the sensor 30 is defined as a first pipeline 31, and the reagent pipeline between the sensor 30 and the reagent storage component 20 is defined as a second pipeline 32. The volume of the first pipeline 31 is smaller than the volume of the second pipeline 32; or, when the cross-sectional areas of the reagent pipelines are equal, the length of the first pipeline 31 is smaller than the length of the second pipeline 32. Among them, the sample detection device of this embodiment can be provided with a machine base, and the reaction component 10, the sensor 30 and other components used for sample detection are all arranged on the machine base, and the exposed position of the machine base is wrapped by the shell 50, so that the sample detection process is carried out in a closed environment, thereby improving the biological safety of the sample detection. The reagent storage component 20 is arranged outside the shell 50 of the machine base, and is connected to the sensor 30 and the reaction component 10 through the reagent pipeline, so that the reagent storage component 20 can store a large capacity of reagents and reduce the volume of the machine base.

[0029] In the embodiment of the present application, the volume of the first pipeline 31 of the sample detection device is smaller than the volume of the second pipeline 32, so that when the user replaces the reagent of the reagent storage assembly 20, the amount of reagent remaining in the first pipeline 31 is less, which can reduce the amount of reagent discarded in the first pipeline 31, reduce reagent waste, and improve the efficiency of reagent use.

[0030] In one embodiment, the sample detection device also includes a sample adding component (not shown), which is used to add the original sample to the reaction component 10, and the reagent storage component 20 is used to transfer the third volume of reagent to the reaction component 10 under the action of a driving force, so that the original sample reacts with the reagent and prepares a sample to be tested.

[0031] Specifically, the sample detection device of this embodiment can be used to detect the original sample that is continuously injected, and the reaction component 10 adds a preset third volume of reagent to the original sample each time, so that the original sample reacts with the reagent and prepares the sample to be tested. Wherein, when the sample detection device includes multiple types of reagents, the third volume can refer to the volume used by each reagent, for example, the third volume can be the diluent volume, hemolytic agent volume, dye solution volume, etc. required for each sample.

[0032] The volume of the first pipeline 31 of the sample detection device of this embodiment is greater than or equal to the third volume, that is, when the reagent of the reagent storage component 20 is replaced, the amount of reagent remaining in the first pipeline 31 is greater than or equal to the amount of reagent required for one sample preparation, so that when the reagent remaining amount of the reagent storage component 20 is insufficient, the reagent stored in the first pipeline 31 can also ensure the normal test of the current sample to be tested or the next sample to be tested, and ensure the accuracy of the sample that has already been tested. In a possible implementation, the controller of the sample detection device initiates an alarm when it recognizes that the sensor 30 indicates that the remaining amount of the reagent storage component 20 is insufficient. When receiving the alarm, the sample detection device can continue to use the reagent in the first pipeline 31 to complete the test of the current sample to be tested, so as to ensure the accuracy of the sample detection.

[0033] Optionally, the sample detection device also includes a pipetting component (not shown), a first connecting end of the pipetting component is connected to the reagent storage component 20 through a second pipeline, and a second connecting end of the pipetting component is connected to the reaction component 10 through a first pipeline. The pipetting component is used to provide driving force for the reagent in the reagent storage component 20 to add the reagent in the reagent pipeline to the reaction component 10.

[0034] Specifically, the sample detection device transfers the reagent through the pipetting component, and the pipetting component is used to provide a driving force for the reagent delivery, so that the reagent in the reagent pipeline is moved into the reaction component 10. In a possible embodiment, the pipetting component may include a quantitative pump or a syringe to quantitatively transfer a preset amount of reagent, and control the reagent delivery state of the reagent pipeline through a switch valve or other device to accurately transfer the reagent to a specified position.

[0035] Furthermore, the sample detection device may include a sample adding component (not shown), which adds a quantitative sample to the reaction component 10 through a sample adding needle. For example, a sample tube loaded with an original sample is moved under the sample adding needle of the sample adding component, and the sample adding needle moves in a vertical direction and punctures the sample tube to absorb the sample to be tested in the sample tube.

[0036] Optionally, the volume of the second pipeline 32 is greater than or equal to twice the third volume, that is, the reagent in the second pipeline 32 can be used to prepare at least two original samples, so that when the reagent in the reagent storage component 20 is exhausted, the reagent in the second pipeline 32 can be used to continue at least two tests, which is convenient for the user to replace the reagent during this period, thereby improving the user's experience.

[0037] The sample detection device includes a housing 50, and the sample detection device shields the reaction component 10, the reaction of the sample to be tested, and the detection process through the housing 50. In one embodiment, see Figure 2 , Figure 2 FIG. 1 is a schematic diagram of the structure of another embodiment of the sample detection device provided by the present application. Figure 2 As shown, the housing 50 is provided with an opening for the reagent pipeline to pass through, and the reagent pipeline enters the housing 50 through the opening, so that the reaction component 10 and the sensor 30 are located inside the housing 50, and the reagent storage component 20 is located outside the housing 50, so that the reagent storage component 20 can be set as a large-capacity liquid storage tank for reagent storage, reducing the reagent replacement operation and improving the user's experience. In another embodiment, the reaction component 10, the sensor 30, and the reagent storage component 20 are all located inside the housing 50, so that the sample detection device is easy to carry and carry, and the sample detection device is suitable for small detection scenarios.

[0038] In one embodiment, see Figure 3 , Figure 3 yes Figure 1 Schematic diagram of the sensor structure. Figure 3 As shown, the sensor 30 includes a transmitter 33 and a receiver 34. The transmitter 33 and the receiver 34 are respectively located on both sides of the reagent pipeline. The transmitter 33 is used to transmit a detection signal to the reagent pipeline.

[0039] Specifically, the sample detection device further includes a processor, which is connected to the transmitter 33 and the receiver 34. The sensor 30 is a bubble detection sensor 30, and the transmitter 33 and the receiver 34 are arranged opposite to each other, and the arrangement direction of the transmitter 33 and the receiver 34 is parallel to the cross section of the reagent pipeline, that is, the infrared light emitted by the transmitter 33 crosses the wall of the reagent pipeline, so that the detection signal emitted by the transmitter 33 can be received by the receiver 34. For example, the sensor 30 can be an ultrasonic bubble sensor 30, an infrared bubble sensor 30, a capacitive bubble sensor 30, etc.

[0040] In one embodiment, the sensor 30 is an infrared bubble sensor 30, and the transmitter 33 is used to transmit an infrared light signal to the reagent pipeline. When there are bubbles in the reagent pipeline and pass through the irradiation position of the transmitter 33, the intensity of the light signal received by the receiver 34 changes. The processor is used to obtain the light signal intensity of the receiver 34, and based on the change in the light signal intensity, determine whether there are bubbles or air columns in the reagent pipeline, and then determine the reagent status of the reagent storage component 20.

[0041] In another embodiment, the sensor 30 is an ultrasonic bubble sensor 30, and the transmitter 33 is used to transmit an ultrasonic signal to the reagent line. When the reagent line is full of reagent, the ultrasonic signal passes through the liquid and reaches the receiver 34 on the opposite side. The processor responds to the receiver 34 receiving the corresponding ultrasonic signal and determines that there is a sufficient amount of reagent stored in the reagent storage assembly 20. When there are bubbles in the reagent line and pass through the irradiation position of the transmitter 33, due to the large acoustic impedance difference between the liquid and the gas and the formation of an acoustic mirror, the ultrasonic signal will be transmitted back to the position of the transmitter 33. The processor responds to the receiver 34 failing to receive the ultrasonic signal and determines that the reagent storage assembly 20 has insufficient reagent remaining.

[0042] In one embodiment, the sample detection device further includes a detection component 40, which is connected to the reaction component 10 via a sample pipeline. The reaction component 10 is used to transfer the sample to be tested to the detection component 40 via the sample pipeline, and the detection component 40 is used to perform sheath flow detection on the sample to be tested.

[0043] Specifically, the detection component 40 can count the cells passing through the detection area by the principle of electrical impedance counting, or the detection component 40 can also classify and count the cells passing through by the laser scattering method. The reaction component 10 is used to transfer the fully reacted sample to be tested from the sample pipeline to the detection component 40. The detection component 40 is used to perform sheath flow detection on the sample to be tested. The sheath flow detection method is to eject the cell suspension made from the sample to be tested from the capillary and flow it through the detection area together with the sheath fluid flowing out from all sides, so that the cell suspension forms a single arranged cell flow. The detection component 40 is used to classify and count the cells passing through one by one to improve the accuracy of sample detection.

[0044] Optionally, see Figure 4 , Figure 4 FIG. 1 is a schematic diagram of the structure of another embodiment of the sample detection device provided by the present application. Figure 4As shown, the reaction component 10 includes a first reaction pool 110 and a second reaction pool 120, and the reagent storage component 20 includes a first storage mechanism 210 and a second storage mechanism 220 for storing different reagents. The first connection end of the first storage mechanism 210 is connected to the first connection end of the first reaction pool 110 through a reagent pipeline, the second connection end of the first storage mechanism 210 is connected to the first connection end of the second reaction pool 120 through a reagent pipeline, and the second storage mechanism 220 is connected to the first connection end or the second connection end of the second reaction pool 120 through a reagent pipeline.

[0045] Specifically, the first reaction pool 110 and the second reaction pool 120 can be two reaction sites arranged in parallel, the first storage mechanism 210 is used to provide the first reaction pool 110 with reagents for the first detection item, and the second storage mechanism 220 is used to provide the second reaction pool 120 with tests for the first detection item and the second detection item, so that the second reaction pool 120 can be suitable for tests of different detection items. For example, the first storage mechanism 210 may include a first dye liquid tank storing a first dye liquid, a first hemolytic agent tank storing a first hemolytic agent, and the second storage mechanism 220 may include a second dye liquid tank storing a second dye liquid, and a second hemolytic agent tank storing a second hemolytic agent. Among them, the reagents stored in the first storage mechanism 210 and the second storage mechanism 220 may be the same or different, or the reagents of the first storage mechanism 210 and the second storage mechanism 220 may partially overlap, which will not be repeated here.

[0046] When the second reaction pool 120 does not need to perform the second detection item, the sample detection device can test the first detection item through the second reaction pool 120. Without adding the first reaction pool 110 and the corresponding supporting valve group pipeline, the second reaction pool 120 can be used as another reaction site for the first test item, thereby reducing the speed limitation of the first test item due to the long incubation time and improving the testing speed and efficiency of the sample detection device.

[0047] Furthermore, the detection component 40 is used to perform a first test item test on the first sample to be tested in the first reaction pool 110 and the second reaction pool 120, or, the detection component 40 is used to perform a first test item test on the first sample to be tested in the first reaction pool 110 and perform a second test item test on the second sample to be tested in the second reaction pool 120.

[0048] Specifically, the sample detection device is in the first detection mode, the first storage mechanism 210 provides the first reagent for the first reaction pool 110 and the second reaction pool 120, and the detection component 40 is used to test the first test item of the first sample to be tested in the first reaction pool 110 and the second reaction pool 120. The sample detection device is in the second detection mode, the first storage mechanism 210 provides the first reagent for the first reaction pool 110, the detection component 40 is used to test the first test item of the first sample to be tested in the first reaction pool 110, the second storage mechanism 220 provides the second reagent for the second reaction pool 120, and the detection component 40 is used to test the second test item of the second sample to be tested in the second reaction pool 120.

[0049] Among them, in the second detection mode, the test of the first detection item can be a four-classification test (DIFF) of white blood cells by laser staining, and the test of the second test item can be a test performed by methodological principles such as laser staining, electrical impedance method, etc. For example, the second test item of the second reaction pool 120 can be at least one of a reticulocyte counting test, a specific protein test, a white blood cell counting test, a basophil classification count, and a nucleated red blood cell classification count. Therefore, the second reaction pool 120 can be used as another reaction site for the first test item without adding the first reaction pool 110 and the corresponding matching valve group pipeline, thereby reducing the speed limitation of the first test item due to the long incubation time, improving the test speed and efficiency of the sample detection device, and reducing the cost of the sample detection device.

[0050] In a possible implementation, the sample detection device may further include a third detection mode. When the sample detection device is in the third detection mode, the first storage mechanism 210 provides the first reagent for the first reaction pool 110, and the second storage mechanism 220 provides the second reagent for the second reaction pool 120, so that the detection component 40 respectively performs tests of different test items on the first reaction pool 110 and the second reaction pool 120. Furthermore, the sample detection device may also adjust the detection mode of the detection component 40 through an external display, control buttons, etc. For example, the user may set the detection component 40 through the display so that the detection component 40 performs sample testing in the first detection mode, the second detection mode, or the third detection mode.

[0051] Optionally, the reagent storage component 20 also includes a third storage mechanism 230, which is used to store diluent, and the first connection end of the third storage mechanism 230 is connected to the third connection end of the second reaction pool 120 through a sample pipeline, the second connection end of the third storage mechanism 230 is connected to the second connection end of the first reaction pool 110 through a sample pipeline, and the third connection end of the third storage mechanism 230 is connected to the detection component 40 through a sample pipeline.

[0052] Specifically, the third storage mechanism 230 may be a diluent bottle. The sample detection device may clean the first reaction pool 110 or the second reaction pool 120 with the diluent of the third storage mechanism 230 to reduce the risk of cross contamination between different samples in the reaction pool. Alternatively, the sample of the first reaction pool 110 or the second reaction pool 120 is diluted with the diluent of the third storage mechanism 230, so that the intercellular distance of the sample to be tested prepared by the first reaction pool 110 or the second reaction pool 120 is increased, so that the detection component 40 is convenient for classifying and counting blood cells.

[0053] In a possible embodiment, the sample detection device may also include a first switch valve and a second switch valve, the first connection end of the first switch valve is connected to the third storage mechanism 230 through a sample pipeline, the second connection end of the first switch valve is connected to the first connection end of the second switch valve through the sample pipeline, the third connection end of the first switch valve is connected to the detection component 40 through the sample pipeline, the second connection end of the second switch valve is connected to the first reaction pool 110 and / or the second reaction pool 120 through the sample pipeline, and the third connection end of the second switch valve is connected to the reagent storage component 20 through the sample pipeline. The sample detection device can control the second switch valve to be turned on and the first switch valve to be turned off, so that the diluent in the third storage mechanism 230 flows into the sample pipeline between the third storage mechanism 230 and the detection component 40; and control the second switch valve to be turned off and the first switch valve to be turned on, so that the sample to be tested prepared by the first reaction pool 110 and / or the second reaction pool 120 flows into the sample pipeline between the first switch valve and the detection component 40; further control the second switch valve to be turned on and the first switch valve to be turned off, so that the sample detection device of this embodiment can push the sample to be tested through the diluent in the third storage mechanism 230, so that the sample to be tested enters the detection component 40 for testing.

[0054] Optionally, the reagent storage assembly 20 also includes an air pressure source (not shown), which is respectively connected to the first storage mechanism 210 and the second storage mechanism 220, and the air pressure source is used to provide a driving force so that the reagents in the first storage mechanism 210 or the second storage mechanism 220 enter the second reaction tank 120 through the reagent pipeline.

[0055] Specifically, the air pressure source of the reagent storage assembly 20 can be connected to the first storage mechanism 210 and the second storage mechanism 220 through a control valve, so as to discharge the reagent in the storage mechanism into the reagent pipeline by changing the air pressure condition of the storage mechanism. Depending on the different connection positions and the different pushing directions, the air pressure source can be a positive pressure source and / or a negative pressure source. In an optional embodiment, the processor of the sample detection device is respectively connected to the air pressure source and the control valve, and the processor is used to control the air pressure source, the control valve and other components, so that the reagents of the first storage mechanism 210 and / or the second storage mechanism 220 can be transported to the first reaction tank 110 or the second reaction tank 120, so as to achieve the reaction and incubation of the sample to be tested, and improve the detection efficiency.

[0056] The above description is only an implementation method of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A sample detection device, characterized in that: include: A reaction component, used for preparing a sample to be tested; A reagent storage component, connected to the reaction component via a reagent pipeline, and the reagent storage component is used to store reagents required for detection; A sensor for detecting the reagent status of the reagent storage component, wherein the sensor is disposed on the reagent pipeline between the reaction component and the reagent storage component; The reagent pipeline between the reaction component and the sensor is a first pipeline, the reagent pipeline between the sensor and the reagent storage component is a second pipeline, and the volume of the first pipeline is smaller than the volume of the second pipeline.

2. The sample detection device according to claim 1, characterized in that: The sample detection device further comprises a sample adding component, the sample adding component is used to add the original sample to the reaction component, and the reagent storage component is used to transfer the third volume of the reagent to the reaction component under the action of the driving force, so that the original sample reacts with the reagent and prepares the sample to be tested; Wherein, the volume of the first pipeline is greater than or equal to the third volume.

3. The sample detection device according to claim 2, characterized in that: The sample detection device also includes a pipetting component, a first connecting end of the pipetting component is connected to the reagent storage component through the second pipeline, and a second connecting end of the pipetting component is connected to the reaction component through the first pipeline. The pipetting component is used to provide a driving force for the reagent in the reagent storage component to add the reagent in the reagent pipeline to the reaction component.

4. The sample detection device according to claim 2, characterized in that: The volume of the second pipeline is greater than or equal to twice the third volume.

5. The sample detection device according to claim 1, characterized in that: The sensor comprises a transmitter and a receiver, wherein the transmitter and the receiver are respectively located at two sides of the reagent pipeline, and the transmitter is used to transmit a detection signal to the reagent pipeline.

6. The sample detection device according to claim 1, characterized in that: The sample detection device further comprises a detection component, which is connected to the reaction component via a sample pipeline, the reaction component is used to transfer the sample to be tested to the detection component via the sample pipeline, and the detection component is used to detect the sample to be tested.

7. The sample detection device according to claim 6, characterized in that: The reaction component includes a first reaction pool and a second reaction pool, and the reagent storage component includes a first storage mechanism and a second storage mechanism for storing different reagents. The first connection end of the first storage mechanism is connected to the first connection end of the first reaction pool through a pipeline, the second connection end of the first storage mechanism is connected to the first connection end of the second reaction pool through a pipeline, and the second storage mechanism is connected to the first connection end or the second connection end of the second reaction pool through a pipeline.

8. The sample detection device according to claim 7, characterized in that: The detection component is used to perform a first test item on the first sample to be tested in the first reaction pool and the second reaction pool, or the detection component is used to perform a first test item on the first sample to be tested in the first reaction pool and perform a second test item on the second sample to be tested in the second reaction pool.

9. The sample detection device according to claim 7, characterized in that: The reagent storage component also includes a third storage mechanism, which is used to store diluent. The first connection end of the third storage mechanism is connected to the third connection end of the second reaction tank through a pipeline, the second connection end of the third storage mechanism is connected to the second connection end of the first reaction tank through a pipeline, and the third connection end of the third storage mechanism is connected to the detection component through a pipeline.

10. The sample detection device according to claim 7, characterized in that: The reagent storage assembly also includes an air pressure source, which is connected to the first storage mechanism and the second storage mechanism respectively, and is used to provide a driving force so that the reagents in the first storage mechanism or the second storage mechanism enter the second reaction pool through a pipeline.

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