Mouse tail cutter convenient for obtaining laboratory mouse tissues

Abstract

The utility model discloses a mouse tail cutter convenient for obtaining laboratory mouse tissues, and relates to the technical field of biomedical experiments. Two limiting plates are fixedly connected to the inner side wall of the operation pipe, two upper cutters and two lower baffles are arranged on the inner sides of the two limiting plates, the two lower baffles are located below the two upper cutters, and the front ends and the rear ends of the upper cutters and the lower baffles are slidably connected with the adjacent side walls of the limiting plates on the front side and the rear side through limiting sliding grooves correspondingly. During use, the tail of an experimental mouse is extracted and then inserted into the operation pipe, and when the lower end of the tail of the experimental mouse is located on the upper end face of the lower baffle, the trigger is pulled towards the grab handle to drive the sliding ring and the sliding block to move towards the grab handle, the upper abutting block moves along the upper abutting groove, and the lower abutting block moves along the lower abutting groove; the two upper cutters get close to each other to cut the tail of the laboratory mouse, meanwhile, the adjacent ends of the two lower baffles are away from each other, and the cut mouse tail tissue directly falls into the EP tube in the limiting frame.

Description

Technical Field

[0001] The utility model relates to the technical field of biomedical experiments, in particular to a mouse tail cutter that is convenient for obtaining experimental mouse tissues. Background Art

[0002] When cultivating knockout mice or conducting certain experiments, it is necessary to obtain part of the mouse tail tissue for mouse genotype identification or other purposes; the existing tools for cutting and obtaining mouse tail tissue are mostly tissue scissors or ophthalmic scissors, but when using scissors to cut mouse tail tissue, it is often difficult to cut the appropriate length of mouse tail tissue because the mouse swings its tail during struggle, resulting in the problem of cutting the mouse blood vessels, causing tail bleeding and then causing wound inflammation and infection. At the same time, when extracting the mouse tail and using scissors, it often causes stress to the experimental mouse, causing the experimental mouse to attack the experimental researchers.

[0003] Secondly, when using scissors to cut off the rat's tail, since the operation is performed in an open environment, the rat's tail tissue stores elastic potential energy during the deformation process. The release of elastic potential energy causes the rat's tail tissue to splash into the open environment and is difficult to collect into the EP tube, causing the rat's tail to easily fall and be exposed to the open environment, resulting in contamination or even loss of the rat's tail tissue to the ground, making it difficult to find and requiring a secondary operation. This not only wastes the experimenter's time, but also further increases the threat of cutting the rat's tail too long and cutting the rat's tail blood vessels.

[0004] In addition, since ophthalmic scissors and tissue scissors are generally stored in an open environment, their metal material is easily oxidized or even rusted when exposed to air and humid environment for a long time. If rusty scissors are used to cut tissue, there is a certain threat to the health of the experimental mice themselves. At the same time, the exposure of scissors to an open environment itself also poses certain safety hazards to experimental researchers.

[0005] Most of the existing devices for cutting mouse tail tissue require two researchers to operate together, which is labor-intensive. A patent with announcement number CN217310382U discloses a device for quickly collecting mouse tail tissue, including a mouse trap box and a mouse tail fixing bolt, the surface wall of the mouse tail fixing bolt is provided with a lower cutting edge, and one end of the mouse tail fixing bolt is provided with a proximal mouse tail clamping plate, and the end of the mouse tail fixing bolt away from the proximal mouse tail clamping plate is provided with a distal mouse tail clamping plate. The utility model is provided with a mouse trap box and a mouse tail fixing bolt, and the surface wall of the mouse tail fixing bolt is provided with a lower cutting edge, the interior of the mouse tail fixing bolt is provided with a hollow shaft, and the proximal mouse tail clamping plate and the distal mouse tail clamping plate are respectively provided at the two ends of the mouse tail fixing bolt located at the hollow shaft. When in use, the transgenic mouse is induced into the mouse trap box, the mouse tail fixing bolt is buckled into the tail of the transgenic mouse, the mouse tail is stuck into the hollow shaft, and a scalpel is used to take samples from the lower cutting edge. The process is simple and quick, and the efficiency of mouse tail sampling is increased.

[0006] The patented device with announcement number CN217310382U is relatively large and inconvenient to operate, and the device is limited by the operating platform and must be placed on a flat table for use. Therefore, this device proposes a mouse tail cutter that is convenient for obtaining experimental mouse tissue to solve the above problem. Utility Model Content

[0007] The utility model aims to provide a mouse tail cutter which is convenient for obtaining experimental mouse tissues, and solves the technical problems raised in the background technology.

[0008] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a mouse tail cutter that is convenient for obtaining experimental mouse tissue, comprising an operating tube, a handle is provided at the lower end of the operating tube, two limit plates are fixedly connected to the inner side wall of the operating tube, the two limit plates are symmetrically arranged in the front and rear directions, two upper cutting knives and two lower baffles are arranged on the inner sides of the two limit plates, the two lower baffles are located below the two upper cutting knives, the adjacent sides of the two upper cutting knives are both sharpened, the front and rear ends of the upper cutting knives and the lower baffle are respectively slidably connected to the adjacent side walls of the limit plates on the front and rear sides through limit sliding grooves, and upper through holes are symmetrically opened on the left and right sides of the side walls of the operating tube. The two lower baffles are located between the two lower through holes, and the two upper cutting knives are located between the two upper through holes. Two upper abutment blocks, two lower abutment blocks and two sliding blocks are arranged on the outer side of the operating tube. The two upper abutment blocks are respectively located on the side away from each other of the two upper cutting knives, and the two lower abutment blocks are respectively located on the side away from each other of the two lower baffles. The upper ends of the two upper abutment blocks away from the side walls are inclined inwardly, and the lower ends of the two lower abutment blocks away from the side walls are inclined inwardly. An upper abutment groove and a lower abutment groove are opened at adjacent ends of the two sliding blocks, and the upper abutment groove and the lower abutment groove are respectively adapted to the upper abutment block and the lower abutment block.

[0009] The lockhole that is formed on the upper and lower ends of the hinge parts of each case is formed on the upper and lower ends of the hinge parts, and the hinge parts are connected with each other with a toothed connection piece at the bottom to form a circuitous bearing on the bottom of the lockhole.

[0010] Preferably, the upper abutment spring and the lower abutment spring are always in a compressed state, when the upper abutment block is located at the lower end of the upper abutment groove, the lower abutment block is located at the middle position of the lower abutment groove, the two upper cutters are away from each other, and the adjacent side walls of the two lower baffles abut.

[0011] Preferably, a sliding ring is sleeved on the operating tube, and the sliding ring is slidingly connected to the operating tube via a limiting sliding groove. Two traction rods are fixedly connected to the upper end of the sliding ring, and one end of the two traction rods away from the sliding ring are respectively fixedly connected to the lower ends of two sliding blocks. A trigger is fixedly connected to the outer wall of the sliding ring, and the trigger is located above the handle.

[0012] Preferably, the lower end of the sliding ring is fixedly connected to a sliding cylinder, and a limiting sliding rod is slidably connected inside the sliding cylinder. The end of the limiting sliding rod away from the sliding cylinder is fixedly connected to the end of the handle close to the trigger. A connecting spring is sleeved on the sliding cylinder, and the two ends of the connecting spring are respectively fixedly connected to the sliding ring and the adjacent side walls of the handle.

[0013] Preferably, a placement hole is provided on the side wall of the operating tube, a limit frame is fixedly connected to the inner wall of the placement hole, the limit frame is located above the placement hole, the limit frame is arranged in an arc shape, an EP tube is arranged in the placement hole, the upper end of the EP tube is located on the inner side of the limit frame, a plurality of abutting anti-slip rubber blocks are fixedly connected to the upper inner wall of the limit frame, and the lower end of the abutting anti-slip rubber block abuts against the upper end of the EP tube.

[0014] Compared with the related art, the rat tail cutter provided by the utility model for facilitating the acquisition of experimental rat tissue has the following beneficial effects:

[0015] 1. The utility model provides a rat tail cutter that is convenient for obtaining experimental rat tissue. In the device, two upper cutters and two lower baffles are arranged in an operating tube. When not in use, the upper abutment block is located at the lowest end of the upper abutment groove under the action of a connecting spring, and the lower abutment block is located at the middle position of the lower abutment groove. At this time, the two upper cutters are away from each other, and the adjacent side walls of the two lower baffles are abutted. When in use, the EP tube is placed in the placement hole, and the position of the EP tube is limited by a limit frame. The handle is held by hand, and the experimental rat tail tissue is extracted and inserted into the operating tube. When the lower end of the experimental rat tail is When it is located at the upper end surface of the lower baffle plate, the trigger is pulled toward the handle to drive the sliding ring to move toward the handle, compress the connecting spring, and drive the sliding block to move toward the handle under the action of the traction rod. The upper abutment block moves along the upper abutment groove, and the lower abutment block moves along the lower abutment groove. The two upper cutters approach each other to cut the tail of the experimental mouse, and at the same time, the adjacent ends of the two lower baffle plates move away from each other, and the cut rat tail directly falls into the EP tube in the limit frame, and the elastic potential energy caused by the deformation of the rat tail cutting will not be released and lost to the external environment, thereby effectively preventing the rat tail from being contaminated or even lost.

[0016] 2. The utility model provides a mouse tail cutter that is convenient for obtaining experimental mouse tissues. The device can be operated by one person and can be operated in any environment, and has a high efficiency and stronger adaptability. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a three-dimensional structural schematic diagram of the utility model;

[0018] Figure 2 for Figure 1 A partial enlarged view of the middle part;

[0019] Figure 3 This is a schematic diagram of the three-dimensional structure of the utility model from another angle;

[0020] Figure 4 for Figure 3 A partial enlarged view of point B in the middle;

[0021] Figure 5 It is a schematic diagram of the three-dimensional structure of the limiting frame of the utility model;

[0022] Figure 6 It is a schematic diagram of the three-dimensional structure of the upper cutter position section of the utility model;

[0023] Figure 7 It is a three-dimensional structural schematic diagram of another angle of the cross section of the upper cutting knife position of the utility model;

[0024] Figure 8 It is a cross-sectional schematic diagram of the cooperation between the sliding block, the upper abutting block and the lower abutting block of the utility model;

[0025] Fig. 9 for Figure 8 A partial enlarged view of point C in the middle;

[0026] Fig.10 It is a schematic diagram of the cross-sectional three-dimensional structure of the sliding block of the utility model.

[0027] In the figure: 1. operating tube; 2. grip; 3. placement hole; 4. EP tube; 5. sliding ring; 6. trigger; 7. traction rod; 8. limit slide rod; 9. sliding cylinder; 10. connecting spring; 11. limit frame; 12. abutment anti-slip rubber block; 13. limit plate; 14. upper cutter; 15. lower baffle plate; 16. lower through hole; 17. upper through hole; 18. lower sliding rod; 19. upper sliding rod; 20. upper connecting rod; 21. lower connecting rod; 22. lower abutment block; 23. upper abutment block; 24. lower abutment spring; 25. upper abutment spring; 26. sliding block; 27. upper abutment groove; 28. lower abutment groove. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all of the embodiments; based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the utility model.

[0029] See also Figure 1-10The utility model provides a technical solution: a mouse tail cutter that is convenient for obtaining experimental mouse tissue, comprising an operating tube 1, a handle 2 is arranged at the lower end of the operating tube 1, two limiting plates 13 are fixedly connected to the inner side wall of the operating tube 1, the two limiting plates 13 are symmetrically arranged in the front and rear directions, two upper cutting knives 14 and two lower baffles 15 are arranged on the inner sides of the two limiting plates 13, the two lower baffles 15 are located below the two upper cutting knives 14, the adjacent sides of the two upper cutting knives 14 are both sharpened, the front and rear ends of the upper cutting knives 14 and the lower baffles 15 are respectively slidably connected to the adjacent side walls of the limiting plates 13 on the front and rear sides through limiting sliding grooves, the upper through holes 17 and the lower through holes 16 are symmetrically opened on the left and right sides of the side wall of the operating tube 1, and the two lower The baffle plate 15 is located between the two lower through holes 16, and the two upper cutters 14 are located between the two upper through holes 17. Two upper abutment blocks 23, two lower abutment blocks 22 and two sliding blocks 26 are arranged on the outer side of the operating tube 1. The two upper abutment blocks 23 are respectively located on the side away from each other of the two upper cutters 14, and the two lower abutment blocks 22 are respectively located on the side away from each other of the two lower baffle plates 15. The upper ends of the two upper abutment blocks 23 away from the side wall are inclined inwardly, and the lower ends of the two lower abutment blocks 22 away from the side wall are inclined inwardly. An upper abutment groove 27 and a lower abutment groove 28 are opened at adjacent ends of the two sliding blocks 26, and the upper abutment groove 27 and the lower abutment groove 28 are respectively adapted to the upper abutment block 23 and the lower abutment block 22;

[0030] Two upper sliding rods 19 are arranged between the upper abutment block 23 and the upper cutter 14, and an upper connecting rod 20 is arranged between the two upper sliding rods 19. Both ends of the upper sliding rod 19 and the upper connecting rod 20 are fixedly connected to the upper abutment block 23 and the adjacent side walls of the upper cutter 14, respectively. The upper sliding rod 19 and the upper connecting rod 20 are both located on the inner side of the upper through hole 17. An upper abutment spring 25 is arranged on the upper connecting rod 20. One end of the upper abutment spring 25 is fixedly connected to the side wall of the upper abutment block 23 close to the upper cutter 14, and the other end of the upper abutment spring 25 is fixedly connected to the operating The outer wall of the operating tube 1 is fixedly connected, two lower sliding rods 18 are arranged between the lower abutting block 22 and the lower baffle 15, and a lower connecting rod 21 is arranged between the two lower sliding rods 18. The left and right ends of the lower sliding rod 18 and the lower connecting rod 21 are respectively fixedly connected to the lower abutting block 22 and the adjacent side walls of the lower baffle 15. A lower abutting spring 24 is sleeved on the lower connecting rod 21, and one end of the lower abutting spring 24 is fixedly connected to the side wall of the lower abutting block 22 close to the lower baffle 15, and the other end of the lower abutting spring 24 is fixedly connected to the outer wall of the operating tube 1;

[0031] The upper abutment spring 25 and the lower abutment spring 24 are always in a compressed state. When the upper abutment block 23 is located at the lowermost end of the upper abutment groove 27, the lower abutment block 22 is located at the middle position of the lower abutment groove 28, the two upper cutters 14 are away from each other, and the two lower baffles 15 are abutted against adjacent side walls. When the trigger 6 is pulled toward the handle 2, the sliding ring 5 is driven to move toward the handle 2, the connecting spring 10 is compressed, and the sliding block 26 is driven to move toward the handle 2 under the action of the traction rod 7. The upper abutment block 23 moves along the upper abutment groove 27, thereby causing the two upper abutment blocks 23 to approach each other, compressing the upper abutment spring 25, and the lower abutment block 22 moves along the lower abutment groove 28, the two lower abutment blocks 22 move away from each other, the lower abutment spring 24 is extended, the two lower baffles 15 are separated, and the two upper cutters 14 approach each other to cut the tail of the experimental mouse. After the two lower baffles 15 are opened, the cut tail tissue falls directly into the EP tube 4 in the limit frame 11;

[0032] A sliding ring 5 is sleeved on the operating tube 1, and the sliding ring 5 is slidably connected to the operating tube 1 through a limiting sliding groove. Two traction rods 7 are fixedly connected to the upper end of the sliding ring 5, and the ends of the two traction rods 7 away from the sliding ring 5 are respectively fixedly connected to the lower ends of the two sliding blocks 26. A trigger 6 is fixedly connected to the outer wall of the sliding ring 5, and the trigger 6 is located above the handle 2. The trigger 6 realizes the operation of the sliding block 26 through the sliding ring 5 and the traction rod 7;

[0033] The lower end of the sliding ring 5 is fixedly connected with a sliding cylinder 9, and a limiting sliding rod 8 is slidably connected inside the sliding cylinder 9. The end of the limiting sliding rod 8 away from the sliding cylinder 9 is fixedly connected to the end of the handle 2 close to the trigger 6. A connecting spring 10 is sleeved on the sliding cylinder 9. The two ends of the connecting spring 10 are respectively fixedly connected to the sliding ring 5 and the adjacent side walls of the handle 2. Under the action of the connecting spring 10, it is ensured that when the device is not in use, the upper abutment block 23 is located at the lowermost end of the upper abutment groove 27, the lower abutment block 22 is located at the middle position of the lower abutment groove 28, the two upper cutters 14 are away from each other, and the adjacent side walls of the two lower baffles 15 are abutted.

[0034] A placement hole 3 is provided on the side wall of the operating tube 1, and a limit frame 11 is fixedly connected to the inner wall of the placement hole 3. The limit frame 11 is located above the placement hole 3 and is arranged in an arc shape. An EP tube 4 is arranged in the placement hole 3, and the upper end of the EP tube 4 is located on the inner side of the limit frame 11. A plurality of abutting anti-slip rubber blocks 12 are fixedly connected to the upper inner wall of the limit frame 11, and the lower end of the abutting anti-slip rubber block 12 abuts against the upper end of the EP tube 4. When the EP tube 4 is installed, the position of the EP tube 4 is limited by the cooperation of the abutting anti-slip rubber block 12 and the lower side wall of the limit frame 11.

[0035] Working principle: When not in use, the upper abutment block 23 is located at the lowest end of the upper abutment groove 27 under the action of the connecting spring 10, and the lower abutment block 22 is located at the middle position of the lower abutment groove 28. At this time, the two upper cutters 14 are away from each other, and the adjacent side walls of the two lower baffles 15 are abutted. When in use, the EP tube 4 is placed in the placement hole 3, and the position of the EP tube 4 is limited by the limit frame 11. Hold the handle 2 with your hand, extract the tail tissue of the experimental mouse and insert it into the operating tube 1. When the lower end of the tail of the experimental mouse is located at the upper end surface of the lower baffle 15, pull the trigger 6 toward the handle 2. The sliding ring 5 is driven to move toward the handle 2, compressing the connecting spring 10, and under the action of the traction rod 7, the sliding block 26 is driven to move toward the handle 2, the upper abutment block 23 moves along the upper abutment groove 27, and the lower abutment block 22 moves along the lower abutment groove 28. The two upper cutting knives 14 approach each other to cut the tail of the experimental mouse, and at the same time, the adjacent ends of the two lower baffles 15 move away from each other, and the cut tail tissue directly falls into the EP tube 4 in the limit frame 11, and the elastic potential energy caused by the deformation of the tail cutting will not be released and lost to the external environment, effectively preventing the tail from being contaminated or even lost.

Claims

1. A rat tail cutter for obtaining experimental rat tissue, comprising an operating tube (1), characterized in that: The lower end of the operating tube (1) is provided with a handle (2), and two limit plates (13) are fixedly connected to the inner side wall of the operating tube (1), and the two limit plates (13) are symmetrically arranged in the front-to-back direction. Two upper cutting knives (14) and two lower baffles (15) are arranged on the inner sides of the two limit plates (13), and the two lower baffles (15) are located below the two upper cutting knives (14). The adjacent sides of the two upper cutting knives (14) are both sharpened, and the front and rear ends of the upper cutting knives (14) and the lower baffles (15) are respectively slidably connected to the adjacent side walls of the limit plates (13) on the front and rear sides through limit sliding grooves. The upper through hole (17) and the lower through hole (16) are symmetrically opened on the left and right sides of the side wall of the operating tube (1), and the two lower baffles (15) are located between the two lower through holes (16). The upper cutter (14) is located between the two upper through holes (17); two upper abutting blocks (23), two lower abutting blocks (22) and two sliding blocks (26) are arranged on the outer side of the operating tube (1); the two upper abutting blocks (23) are respectively located on the side away from each other of the two upper cutters (14); the two lower abutting blocks (22) are respectively located on the side away from each other of the two lower baffles (15); the upper ends of the two upper abutting blocks (23) away from the side wall are inclined inwardly; the lower ends of the two lower abutting blocks (22) away from the side wall are inclined inwardly; the adjacent ends of the two sliding blocks (26) are provided with an upper abutting groove (27) and a lower abutting groove (28); the upper abutting groove (27) and the lower abutting groove (28) are respectively adapted to the upper abutting block (23) and the lower abutting block (22).

2. A rat tail cutter for obtaining experimental rat tissue according to claim 1, characterized in that: Two upper sliding rods (19) are arranged between the upper abutment block (23) and the upper cutter (14); an upper connecting rod (20) is arranged between the two upper sliding rods (19); both ends of the upper sliding rod (19) and the upper connecting rod (20) are respectively fixedly connected to the adjacent side walls of the upper abutment block (23) and the upper cutter (14); both the upper sliding rod (19) and the upper connecting rod (20) are located on the inner side of the upper through hole (17); an upper abutment spring (25) is arranged on the upper connecting rod (20); one end of the upper abutment spring (25) is fixedly connected to the side wall of the upper abutment block (23) close to the upper cutter (14); the other end of the upper abutment spring (25) is fixedly connected to the side wall of the upper abutment block (23) close to the upper cutter (14); The lower connecting rod (21) is fixedly connected to the outer wall of the operating tube (1), two lower sliding rods (18) are arranged between the lower abutting block (22) and the lower baffle (15), and a lower connecting rod (21) is arranged between the two lower sliding rods (18). The left and right ends of the lower sliding rod (18) and the lower connecting rod (21) are respectively fixedly connected to the adjacent side walls of the lower abutting block (22) and the lower baffle (15), and a lower abutting spring (24) is sleeved on the lower connecting rod (21), one end of the lower abutting spring (24) is fixedly connected to the side wall of the lower abutting block (22) close to the lower baffle (15), and the other end of the lower abutting spring (24) is fixedly connected to the outer wall of the operating tube (1).

3. A rat tail cutter for obtaining experimental rat tissue according to claim 2, characterized in that: The upper abutment spring (25) and the lower abutment spring (24) are always in a compressed state. When the upper abutment block (23) is located at the lowermost end of the upper abutment groove (27), the lower abutment block (22) is located at the middle position of the lower abutment groove (28), the two upper cutters (14) are away from each other, and the adjacent side walls of the two lower baffles (15) are in abutment with each other.

4. The rat tail cutter for obtaining experimental rat tissue according to claim 1, characterized in that: The operating tube (1) is sleeved with a sliding ring (5), and the sliding ring (5) is slidably connected to the operating tube (1) via a limiting sliding groove. The upper end of the sliding ring (5) is fixedly connected to two traction rods (7), and the ends of the two traction rods (7) away from the sliding ring (5) are respectively fixedly connected to the lower ends of two sliding blocks (26). The outer wall of the sliding ring (5) is fixedly connected to a trigger (6), and the trigger (6) is located above the handle (2).

5. A rat tail cutter for obtaining experimental rat tissue according to claim 4, characterized in that: The lower end of the sliding ring (5) is fixedly connected to a sliding cylinder (9), and a limiting sliding rod (8) is slidably connected inside the sliding cylinder (9). The end of the limiting sliding rod (8) away from the sliding cylinder (9) is fixedly connected to the end of the handle (2) close to the trigger (6). A connecting spring (10) is sleeved on the sliding cylinder (9), and the two ends of the connecting spring (10) are respectively fixedly connected to the sliding ring (5) and the adjacent side walls of the handle (2).

6. The rat tail cutter for obtaining experimental rat tissue according to claim 1, characterized in that: A placement hole (3) is provided on the side wall of the operating tube (1); a limit frame (11) is fixedly connected to the inner side wall of the placement hole (3); the limit frame (11) is located above the placement hole (3); the limit frame (11) is arranged in an arc shape; an EP tube (4) is arranged in the placement hole (3); the upper end of the EP tube (4) is located inside the limit frame (11); a plurality of abutting anti-skid rubber blocks (12) are fixedly connected to the upper inner wall of the limit frame (11); the lower end of the abutting anti-skid rubber block (12) abuts against the upper end of the EP tube (4).

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