Fluorescence polarization instrument for detecting brucellosis

By designing the limit and push mechanism in the brucellosis detection fluorescence polarizer, the sample tilt and installation instability caused by the rotation of the sample door is solved, and the stability and detection efficiency of the swab during the detection process are improved. .

CN222365001UActive Publication Date: 2025-01-17PEOPLES HOSPITAL OF INNER MONGOLIA AUTONOMOUS REGION
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Patent Information

Application Number
CN202420874810.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-23
Publication Date
2025-01-17
Estimated Expiration
2034-04-23

AI Technical Summary

Technical Problem

The existing brucellosis detection fluorescent polarizers are used to tilt the sample due to the rotation of the sample door during swab placement, which affects the detection efficiency, and the sample door cannot be stably installed on the instrument, reducing the stability of the device.

Method used

A fluorescence polarizer including a limiting mechanism and a pushing mechanism is designed. The limiting mechanism ensures that the sample door is stably stuck to the chassis after placing the swab; the pushing mechanism is used to cooperate with the positioning port, pin block, clamp and spring. Through the cooperation of the motor, screw and slide rod, the sample door is smoothly pushed and closed, ensuring the stability of swab clamping.

Benefits of technology

It improves the stability between the sample door and the chassis, ensures the stability of the swab during the detection process, improves the detection efficiency, and prevents the swab from overflowing, enhancing the practicality of the device.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a fluorescence polarization instrument for brucellosis detection, belongs to the technical field of biological detection equipment, and aims to solve the problems that a sample door needs to be obliquely rotated to influence placement of a swab and the sample door cannot be stably mounted on the instrument. A sample door is arranged on the front side of the case, a control switch is fixedly mounted on the front side of the sample door, a limiting mechanism is arranged on the case at the upper part of the sample door, the sample door and the case are connected through the limiting mechanism, a clamping device is fixedly mounted on the inner side of the sample door, and a pushing mechanism is arranged between the sample door and the case; through the arrangement of the limiting mechanism, when a swab is placed on the sample door, is clamped by the clamping device and then is fed into the case for detection, the sample door can be stably and quickly mounted on the case, the stability between the sample door and the case is improved, the stability of the swab on the sample door in the detection process is ensured, and the detection efficiency is improved.
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Description

Technical Field

[0001] The utility model belongs to the technical field of biological testing equipment, and in particular relates to a fluorescence polarization instrument used for brucellosis detection. Background Art

[0002] The fluorescence polarimeter for brucellosis detection uses a unique fluorescence polarization detection principle to measure the rotation time of polarized light to detect antibodies in serum, and determines the positive or negative result based on the mp reading displayed by the FPA detector. The fluorescence polarization assay is a uniform detection method that does not require a washing step or removal of unreacted components. It is used for epidemiological surveys and on-site testing for epidemic response, and for rapid testing of suspected cases in clinical laboratories and disease control laboratories. It can detect all Brucella antibodies in human serum, including all types of antibodies such as IgG1, IgG2, IgG3, IgG4, IgM, IgA, and IgD.

[0003] The prior art discloses a fluorescence polarimeter for brucellosis detection with patent announcement number CN217981251U, which comprises a chassis, a socket is arranged on the left side of the chassis, a sample door is arranged on the front side of the chassis through a chain, a support rod and a claw extending to the outside of the sample door are installed inside the sample door through a driving mechanism, a steel wire rope is arranged at the bottom of the driving mechanism, an iron block fixedly connected to the steel wire seam is slidably installed inside the sample door, an electromagnet located at the bottom of the iron block is arranged inside the sample door, an installation cavity is opened inside the sample door, and the hinge comprises an insulating shaft, a bearing, an insulating ring, an inner conductive sheet and an outer conductive sheet. The fluorescence polarimeter for brucellosis detection has the advantage of convenient swab installation, which solves the problem that the swab needs to be manually placed in the instrument, the device for fixing the swab has a simple structure, requires two-handed operation, and is easily unstable in fixation. However, the following deficiencies still exist in actual use: From a practical point of view, the swab is clamped by rotating the sample door when it is placed in the instrument. Since the rotation of the sample door will form a certain tilt angle, the sample will tilt and overflow during the clamping process of the swab, thereby affecting the detection efficiency. At the same time, the sample door cannot be stably detachably installed on the instrument, which reduces the stability.

[0004] Therefore, there is a need for a fluorescence polarimeter for brucellosis detection to solve the problems in the prior art that the sample door needs to be tilted and rotated, affecting the placement of the swab and the sample door cannot be stably installed on the instrument. Utility Model Content

[0005] The utility model aims to provide a fluorescence polarization instrument for brucellosis detection to solve the problems raised in the above-mentioned background technology.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a fluorescence polarimeter for brucellosis detection, comprising a chassis, a socket is provided on the left side of the chassis, a sample door is provided on the front side of the chassis, a control switch is fixedly installed on the front side of the sample door, a limiting mechanism is provided on the upper part of the sample door on the chassis and is connected through the limiting mechanism, a clamping device is fixedly installed on the inner side of the sample door, and a pushing mechanism is provided between the sample door and the chassis.

[0007] It should be noted in the scheme that the limiting mechanism includes a positioning port, which is opened on the chassis, and a connecting plate is fixedly connected to the chassis on the rear side of the positioning port. A pin block is provided in the positioning port, and fixed shafts are fixedly connected on both sides of the pin block. The positioning port is rotatably connected to the pin block through the fixed shaft, a spring is fixedly installed on the bottom of the connecting plate and is connected to the pin block, and a card block is fixedly connected to the sample door on the front side of the positioning port.

[0008] It is further worth mentioning that the positioning opening is provided through the upper part and the front part of the chassis, and the card block is provided to match the positioning opening.

[0009] It should be further explained that the pin block is of a special shape and is formed by integral processing.

[0010] As a preferred embodiment, the pushing mechanism includes an installation groove, which is opened at the bottom of the sample door, and a motor is fixedly installed in the installation groove. A screw rod is fixedly connected to the output end of the motor, and sliding rods are fixedly connected to the surface of the sample door on the left and right sides of the screw rod, and the screw rod corresponds to a matching threaded groove opened on the chassis, and a limiting plate is fixedly connected to the top of the inner side of the sample door above the sliding rod, and the limiting plate corresponds to a sliding groove opened on the chassis.

[0011] As a preferred embodiment, the slide bar corresponds to a matching limiting hole opened on the chassis and slides inside, and the limiting plate slides in the chassis through a sliding groove.

[0012] As a preferred implementation manner, the motor is electrically connected to the control switch.

[0013] Compared with the prior art, the fluorescence polarization instrument for brucellosis detection provided by the utility model has at least the following beneficial effects:

[0014] (1) Through the setting of the limiting mechanism, when the swab is placed on the sample door and clamped by the clamping device and then sent into the chassis for detection, the sample door can be stably and quickly installed on the chassis, thereby improving the stability between the two, ensuring the stability of the swab on the sample door during the detection process, and improving the detection efficiency.

[0015] (2) Through the push mechanism, the sample door can be pushed and operated smoothly on the chassis, which makes it convenient to clamp and remove the swab, facilitates detection, improves the stability of swab clamping, prevents swab overflow, facilitates detection, and improves the practicality of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a schematic diagram of the first state structure of the utility model;

[0017] Figure 2 This is a schematic diagram of the second state structure of the utility model;

[0018] Figure 3 It is a side view cutaway schematic diagram of the internal structure of the utility model;

[0019] Figure 4 It is a partial cutaway structural schematic diagram of the limiting mechanism of the utility model;

[0020] Figure 5 for Figure 3 Schematic diagram of the structure enlarged at point A in the middle.

[0021] In the figure: 1, chassis; 101, socket; 2, sample door; 201, control switch; 3, limit mechanism; 301, pin block; 302, clamping block; 303, positioning port; 304, connecting plate; 305, spring; 306, fixed shaft; 4, pushing mechanism; 401, screw rod; 402, sliding rod; 403, limit plate; 404, motor; 405, threaded groove; 406, sliding groove; 407, mounting groove; 5, clamping device. DETAILED DESCRIPTION

[0022] The present invention will be further described below in conjunction with the embodiments.

[0023] See also Figure 1-5 The utility model provides a fluorescence polarimeter for brucellosis detection, including a chassis 1, a socket 101 is arranged on the left side of the chassis 1, a sample door 2 is arranged on the front side of the chassis 1, a control switch 201 is fixedly installed on the front side of the sample door 2, a limiting mechanism 3 is arranged on the upper part of the sample door 2 on the chassis 1 and is connected through the limiting mechanism 3, a clamping device 5 is fixedly installed on the inner side of the sample door 2, and a pushing mechanism 4 is arranged between the sample door 2 and the chassis 1.

[0024] The clamping device 5 has been specifically disclosed in the patent announcement number CN217981251U, and will not be elaborated on here. The limiting mechanism 3 can facilitate the sample door 2 to be stably connected to the chassis 1, and it can be quickly released to facilitate the opening and closing of the sample door 2. It cooperates with the pushing mechanism 4 to ensure the stability of the opening and closing of the sample door 2, improve the stability of the swab, and facilitate detection.

[0025] Further as Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, it is worth explaining in detail that the limiting mechanism 3 includes a positioning port 303, the positioning port 303 is opened on the chassis 1, and a connecting plate 304 is fixedly connected to the chassis 1 on the rear side of the positioning port 303, a pin block 301 is arranged in the positioning port 303, and fixed shafts 306 are fixedly connected on both sides of the pin block 301. The positioning port 303 is rotatably connected to the pin block 301 through the fixed shaft 306, and a spring 305 is fixedly installed at the bottom of the connecting plate 304 and is connected to the pin block 301. The front side of the positioning port 303 corresponds to a clamping block 302 fixedly connected to the sample door 2, the positioning port 303 is set through the upper and front parts of the chassis 1, the clamping block 302 is matched with the positioning port 303, and the pin block 301 is a special-shaped setting, which is formed by integral processing.

[0026] Pressing the pin block 301 causes the pin block 301 to rotate in the positioning port 303 via the fixed shaft 306, thereby disengaging the pin block 301 and the clamping block 302, releasing the clamping of the sample door 2. At the same time, the pin block 301 is squeezed by the elastic force of the spring 305 to ensure the stability of the clamping process.

[0027] According to the above working process, it can be known that: through the setting of the limiting mechanism 3, when the swab is placed on the sample door 2 and clamped by the clamping device 5 and then sent into the chassis 1 for detection, the sample door 2 can be stably and quickly installed on the chassis 1, thereby improving the stability between the two, ensuring the stability of the swab on the sample door 2 during the detection process, and improving the detection efficiency.

[0028] Further as Figure 2 and Figure 3 As shown, it is worth specifically explaining that the pushing mechanism 4 includes a mounting groove 407, which is opened at the bottom of the sample door 2, and a motor 404 is fixedly installed in the mounting groove 407. A screw rod 401 is fixedly connected to the output end of the motor 404, and sliding rods 402 are fixedly connected to the surface of the sample door 2 on the left and right sides of the screw rod 401. The screw rod 401 corresponds to a matching threaded groove 405 opened on the chassis 1, and a limiting plate 403 is fixedly connected to the top of the inner side of the sample door 2 above the sliding rod 402, and the limiting plate 403 corresponds to a sliding groove 406 opened on the chassis 1. The sliding rod 402 corresponds to a matching limiting hole opened on the chassis 1 and slides inside. The limiting plate 403 slides in the chassis 1 through the sliding groove 406, and the motor 404 is electrically connected to the control switch 201.

[0029] The motor 404 is controlled by the control switch 201, and the screw rod 401 is rotated to make the sample door 2 slide and be pushed out on the chassis 1 through the slide bar 402 and the limit plate 403, so that the sample door 2 is opened and closed, and runs stably at the same time to ensure the stability of the swab.

[0030] This solution has the following working process: when this device is used, when it is necessary to open the sample door 2 to place a swab, the pin block 301 is pressed at this time, so that the pin block 301 rotates in the positioning port 303 through the fixed shaft 306, so that the pin block 301 and the clamping block 302 are disengaged. At this time, the motor 404 is controlled to run by the control switch 201, and the sample door 2 slides and is pushed out on the chassis 1 through the sliding rod 402 and the limit plate 403 through the rotation of the screw rod 401, so that it is convenient to clamp the swab on the sample door 2 through the clamping device 5. After the installation is completed, the motor 404 is controlled to run in the reverse direction by the control switch 201, so that the sample door 2 is rotated and pushed into the chassis 1 through the screw rod 401 and closed on the chassis 1. At this time, the sample door 2 is fixedly installed on the chassis 1 through the clamping connection between the clamping block 302 and the pin block 301, and the pin block 301 is squeezed by the elastic force of the spring 305 to ensure the stability of the clamping process.

[0031] In summary: through the setting of the limiting mechanism 3, when the swab is placed on the sample door 2 and clamped by the clamping device 5 and then sent into the chassis 1 for detection, the sample door 2 can be stably and quickly installed on the chassis 1, thereby improving the stability between the two, ensuring the stability of the swab on the sample door 2 during the detection process, and improving the detection efficiency; through the setting of the pushing mechanism 4, the sample door 2 can be pushed and operated smoothly on the chassis 1, so that the swab can be clamped and removed conveniently, which is convenient for detection, improves the stability of the swab clamping, prevents the swab from overflowing, facilitates detection, and improves the practicability of the device.

Claims

1. A fluorescence polarimeter for brucellosis detection, comprising a chassis (1), characterized in that: The left side of the chassis (1) is provided with a socket (101), the front side of the chassis (1) is provided with a sample door (2), the front side of the sample door (2) is fixedly mounted with a control switch (201), the upper part of the sample door (2) is provided with a limit mechanism (3) on the chassis (1) and is connected via the limit mechanism (3), the inner side of the sample door (2) is fixedly mounted with a clamping device (5), and a pushing mechanism (4) is provided between the sample door (2) and the chassis (1).

2. A fluorescence polarimeter for brucellosis detection according to claim 1, characterized in that: The limiting mechanism (3) comprises a positioning opening (303), wherein the positioning opening (303) is provided on the chassis (1), a connecting plate (304) is fixedly connected to the chassis (1) at the rear side of the positioning opening (303), a pin block (301) is arranged in the positioning opening (303), fixed shafts (306) are fixedly connected to both sides of the pin block (301), the positioning opening (303) is rotatably connected to the pin block (301) via the fixed shaft (306), a spring (305) is fixedly installed at the bottom of the connecting plate (304) and is connected to the pin block (301), and a clamping block (302) is fixedly connected to the front side of the positioning opening (303) corresponding to the sample door (2).

3. A fluorescence polarimeter for brucellosis detection according to claim 2, characterized in that: The positioning opening (303) is provided through the upper part and the front part of the chassis (1), and the clamping block (302) is provided to match the positioning opening (303).

4. A fluorescence polarimeter for brucellosis detection according to claim 2, characterized in that: The pin block (301) is of a special shape and is formed by integral processing.

5. A fluorescence polarimeter for brucellosis detection according to claim 1, characterized in that: The pushing mechanism (4) comprises a mounting groove (407), wherein the mounting groove (407) is provided at the bottom of the sample door (2), wherein a motor (404) is fixedly installed in the mounting groove (407), wherein a lead screw (401) is fixedly connected to the output end of the motor (404), wherein sliding rods (402) are fixedly connected to the surface of the sample door (2) on the left and right sides of the lead screw (401), wherein the lead screw (401) is provided with a matching threaded groove (405) on the case (1), wherein a limit plate (403) is fixedly connected to the top of the inner side of the sample door (2) above the sliding rod (402), wherein the limit plate (403) is provided with a sliding groove (406) on the case (1).

6. A fluorescence polarimeter for brucellosis detection according to claim 5, characterized in that: The sliding rod (402) corresponds to a matching limiting hole opened on the chassis (1) and slides inside, and the limiting plate (403) slides inside the chassis (1) through a sliding groove (406).

7. A fluorescence polarimeter for brucellosis detection according to claim 5, characterized in that: The motor (404) is electrically connected to the control switch (201).

Citation Information

Patent Citations

  • Fluorescence polarization instrument for detecting brucellosis

    CN217981251U