Magnetic bead transfer device for chemiluminescence immunity analyzer

Abstract

The utility model provides a magnetic bead transfer device for a chemiluminescence immunoassay analyzer. The magnetic bead transfer device comprises a stirring rod, a magnetic rod, a first driving motor for controlling the stirring rod to rotate and a second driving motor for controlling the stirring rod to move, a first convex piece and a second convex piece are arranged at one end, close to the kit, of the stirring rod; the second convex piece and the first convex piece are symmetrically arranged; the other end of the stirring rod is sleeved with a magnetic attraction ring, the magnetic attraction ring is connected with a magnet in a magnetic attraction mode, and the magnet is connected with the first driving motor. The kit is placed under the stirring rod, and the bottom of the kit is connected with a driving base for driving the kit to rotate; an inner cavity is formed in the stirring rod, a through hole is formed in the magnet, and the inner cavity and the through hole form a cavity for the magnetic rod to penetrate through; the magnetic bar is accommodated in the cavity; the labor cost is reduced, different detection requirements are met, and the sensitivity and the accuracy are improved.

Description

Technical Field

[0001] The present application relates to the field of in vitro diagnostic (IVD) detectors, and in particular to a magnetic bead transfer device for a chemiluminescent immunoassay analyzer. Background Art

[0002] In the field of medical diagnosis, chemiluminescence immunoassay analyzers have always played an important role. Their principle is based on chemiluminescence reaction and they have high sensitivity and a wide range of applications.

[0003] The principle of traditional chemiluminescence analyzers is based on chemiluminescence reactions, which are performed by detecting the light signals generated when specific substances in the sample react with labeled fluorescent substances. This principle gives it a unique advantage in detection sensitivity, and it can detect extremely small amounts of biological molecules, and is widely used in in vitro diagnosis, biomedical research and other fields.

[0004] However, traditional chemiluminescence analyzers also have a series of difficulties and defects in research and development and application, mainly including possible contamination, low sensitivity and low accuracy. Utility Model Content

[0005] In view of the above problems, the present application is proposed to provide a magnetic bead transfer device for a chemiluminescent immunoassay analyzer that overcomes the above problems or at least partially solves the above problems, comprising:

[0006] A magnetic bead transfer device for a chemiluminescent immunoassay analyzer, comprising a stirring rod, a magnetic rod, a first drive motor for controlling the rotation of the stirring rod, and a second drive motor for controlling the displacement of the stirring rod;

[0007] The stirring rod is provided with a first protrusion at one end close to the reagent box and a second protrusion symmetrically arranged with respect to the first protrusion;

[0008] The other end of the stirring rod is sleeved with a magnetic ring, the magnetic ring is magnetically connected to a magnet, and the magnet is connected to the first drive motor; the first drive motor is arranged on one side of the fixed block, and the other side of the fixed block is connected to the second drive motor through a transmission module, and the transmission module is arranged on the top of the fixed seat;

[0009] The reagent box is placed directly below the stirring rod, and the bottom of the reagent box is connected to a driving base for driving the reagent box to rotate;

[0010] An inner cavity is provided in the stirring rod, and a through hole is provided in the magnet. The inner cavity and the through hole form a cavity for the magnetic rod to pass through; the fixed block is provided with a third drive motor for controlling the up and down displacement of the magnetic rod, the third drive motor is connected to the magnetic rod, and the magnetic rod is stored in the cavity; the third drive motor is arranged in parallel with the stirring rod.

[0011] Furthermore, it also includes a gear set, wherein the gear set includes a driving wheel and a transmission wheel;

[0012] The first driving motor is connected to the driving wheel, the driving wheel is meshingly connected to the transmission wheel, the transmission wheel is connected to the through hole of the magnet, and the transmission wheel is provided with a first opening for the magnetic rod to pass through.

[0013] Further, it also includes a first extension member and a second extension member;

[0014] The first driving motor is connected to the driving wheel through the first extension member, the first driving motor is arranged at the top of the first extension member, the driving wheel is arranged at the bottom of the first extension member, the driving wheel and the transmission wheel are both arranged at the top of the second extension member, and the transmission wheel is connected to the through hole of the magnet through the second opening of the second extension member;

[0015] One side of the first extension piece is fixedly connected to the fixing block;

[0016] One side of the second extension piece is fixedly connected to the fixing block.

[0017] Furthermore, it also includes a transmission tube, the outer wall of one end of the transmission tube is fixedly connected to the inner wall of the transmission wheel, the outer wall of the other end of the transmission tube is fixedly connected to the inner wall of the magnet, and the transmission tube passes through the second opening to connect the transmission wheel and the magnet respectively.

[0018] Further, the transmission module includes a movable block and a guide rail;

[0019] One side of the movable block is connected to the fixed block, and the other side of the movable block is movably connected to the guide rail; the movable block is connected to the second driving motor.

[0020] Furthermore, it also includes a positioning detector, which is arranged on the fixed block and is arranged parallel to the magnetic attraction ring.

[0021] Furthermore, the driving base includes a bearing fixture and a fourth driving motor;

[0022] The top of the carrying fixture is provided with a receiving groove for placing the reagent kit;

[0023] The bottom of the supporting fixture is connected to the fourth driving motor.

[0024] Furthermore, it also includes a load-bearing base, and the driving base and the fixing base are both arranged on the top of the load-bearing base.

[0025] Furthermore, it also includes a connecting piece, one end of which is connected to the magnetic bar, and one end of which is connected to the third driving motor.

[0026] Furthermore, it also includes a power interface, which is electrically connected to the first drive motor, the second drive motor, the third drive motor and the drive base respectively.

[0027] This application has the following advantages:

[0028] In the embodiments of the present application, relative to the prior art that "traditional chemiluminescence instruments also have a series of difficulties and defects in research and development and application, mainly including possible contamination, low sensitivity and low accuracy", the present application provides a solution of "a magnetic bead transfer device for a chemiluminescence immunoassay analyzer", specifically: "a magnetic bead transfer device for a chemiluminescence immunoassay analyzer, comprising a stirring rod, a magnetic rod, a first drive motor for controlling the rotation of the stirring rod and a second drive motor for controlling the displacement of the stirring rod; the stirring rod is provided with a first protrusion at one end close to the reagent box and a second protrusion symmetrically arranged with the first protrusion; the other end of the stirring rod is sleeved with a magnetic attraction ring, and the magnetic attraction ring magnetically The stirring rod is provided with a suction connection magnet, the magnet is connected to the first driving motor; the first driving motor is arranged on one side of the fixed block, the other side of the fixed block is connected to the second driving motor through a transmission module, and the transmission module is arranged on the top of the fixed seat; the reagent box is placed directly below the stirring rod, and the bottom of the reagent box is connected to a driving base for driving the reagent box to rotate; an inner cavity is provided in the stirring rod, a through hole is provided in the magnet, and the inner cavity and the through hole form a cavity for the magnetic rod to pass through; the fixed block is provided with a third driving motor for controlling the up and down displacement of the magnetic rod, the third driving motor is connected to the magnetic rod, and the magnetic rod is stored in the cavity; the third driving motor is arranged in parallel with the stirring rod. The "stirring rod, magnetic rod, first drive motor and second drive motor" solves the problem of "traditional instruments are easily affected by contamination during use, which is mainly reflected in the number of cleaning times and the loss of nano-magnetic beads during the cleaning process. Too little cleaning will lead to too high background signal, seriously affecting the accuracy of the detection, while too much cleaning will cause serious loss of magnetic beads, thereby reducing the sensitivity and accuracy of the instrument." The effect of "reducing labor costs, meeting different detection needs, improving sensitivity and accuracy, and achieving the sensitivity and accuracy of traditional chemistry without designing complex pipeline settings and cleaning procedures" is achieved. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the technical solution of the present application, the drawings required for use in the description of the present application will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative labor.

[0030] Figure 1 It is a structural schematic diagram of a magnetic bead transfer device for a chemiluminescent immunoassay analyzer provided in one embodiment of the present application;

[0031] Figure 2It is a detailed schematic diagram of a magnetic bead transfer device for a chemiluminescent immunoassay analyzer provided in one embodiment of the present application;

[0032] Figure 3 It is a detailed schematic diagram of a magnetic bead transfer device for a chemiluminescent immunoassay analyzer provided in one embodiment of the present application;

[0033] Figure 4 It is a detailed cross-sectional view of a magnetic bead transfer device for a chemiluminescent immunoassay analyzer provided in one embodiment of the present application.

[0034] In the accompanying drawings: 1. stirring rod; 2. magnetic rod; 3. first drive motor; 4. second drive motor; 5. first protrusion; 6. second protrusion; 7. magnetic attraction ring; 8. magnet; 9. reagent box; 10. fixed block; 11. cavity; 12. third drive motor; 13. driving wheel; 14. transmission wheel; 15. first opening; 16. first extension piece; 17. second extension piece; 18. transmission tube; 19. movable block; 20. guide rail; 21. positioning detector; 22. bearing fixture; 23. fourth drive motor; 24. load-bearing base; 25. fixed seat; 26. connector; 27. power interface. DETAILED DESCRIPTION

[0035] In order to make the objects, features and advantages of the present application more obvious and understandable, the present application is further described in detail below in conjunction with the accompanying drawings and specific implementation methods. Obviously, the described embodiments are part of the embodiments of the present application, rather than all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present application.

[0036] The inventors analyzed the prior art and found that chemiluminescent immunoassay analyzers have always played an important role in the field of medical diagnosis. Their principle is based on chemiluminescent reaction, and they have high sensitivity and a wide range of applications. Traditional chemiluminescent analyzers face a series of difficulties and defects during the research and development process, which limits their application in some specific environments and occasions. In order to solve these problems, our team successfully developed a new type of chemiluminescent immunoassay analyzer, which overcomes the various drawbacks of traditional instruments and provides a more convenient and efficient solution for medical diagnosis.

[0037] The principle of traditional chemiluminescence analyzers is based on chemiluminescence reactions, and the analysis is performed by detecting the light signal generated when specific substances in the sample react with labeled fluorescent substances. This principle gives it a unique advantage in detection sensitivity, and it can detect extremely small amounts of biological molecules, and is widely used in in vitro diagnosis, biomedical research and other fields. However, traditional chemiluminescence analyzers also have a series of difficulties and defects in their research and development and application, mainly including problems of contamination, sensitivity and accuracy.

[0038] First, traditional instruments are susceptible to contamination during use, which is mainly reflected in the number of cleanings and the loss of nanomagnetic beads during the cleaning process. Too little cleaning will result in too high a background signal, seriously affecting the accuracy of the test, while too much cleaning will cause a serious loss of magnetic beads, thereby reducing the sensitivity and accuracy of the instrument. In addition, traditional instruments are complex in design and require regular maintenance and professional operation, which greatly increases the cost of research and development, manufacturing, and operation and maintenance, limiting their application in some places. In addition, the inability to provide single-person reagents can easily lead to problems of reagent expiration and waste.

[0039] Reference Figure 1-4 , showing a structural schematic diagram, a detailed schematic diagram and a detailed cross-sectional diagram of a magnetic bead transfer device for a chemiluminescent immunoassay analyzer provided in one embodiment of the present application;

[0040] A magnetic bead transfer device for a chemiluminescent immunoassay analyzer, comprising a stirring rod 1, a magnetic rod 2, a first drive motor 3 for controlling the rotation of the stirring rod 1, and a second drive motor 4 for controlling the displacement of the stirring rod 1;

[0041] The stirring rod 1 is provided with a first protrusion 5 and a second protrusion 6 symmetrically arranged with respect to the first protrusion 5 at one end close to the reagent box 9;

[0042] The other end of the stirring rod 1 is sleeved with a magnetic ring 7, the magnetic ring 7 is magnetically connected to a magnet 8, and the magnet 8 is connected to the first drive motor 3; the first drive motor 3 is arranged on one side of the fixed block 10, and the other side of the fixed block 10 is connected to the second drive motor 4 through a transmission module, and the transmission module is arranged on the top of the fixed seat 25;

[0043] The reagent box 9 is placed directly below the stirring rod 1, and the bottom of the reagent box 9 is connected to a driving base for driving the reagent box 9 to rotate;

[0044] The stirring rod 1 is provided with an inner cavity, and the magnet 8 is provided with a through hole, and the inner cavity and the through hole form a cavity 11 for the magnetic rod 2 to pass through; the fixed block 10 is provided with a third drive motor 12 for controlling the up and down displacement of the magnetic rod 2, and the third drive motor 12 is connected to the magnetic rod 2, and the magnetic rod 2 is accommodated in the cavity 11; the third drive motor 12 is arranged parallel to the stirring rod 1.

[0045] In the embodiments of the present application, relative to the prior art that "traditional chemiluminescence instruments also have a series of difficulties and defects in research and development and application, mainly including possible contamination, low sensitivity and low accuracy", the present application provides a solution of "a magnetic bead transfer device for a chemiluminescence immunoassay analyzer", specifically: "a magnetic bead transfer device for a chemiluminescence immunoassay analyzer, comprising a stirring rod 1, a magnetic rod 2, a first drive motor 3 for controlling the rotation of the stirring rod 1 and a second drive motor 4 for controlling the displacement of the stirring rod 1; the stirring rod 1 is provided with a first protrusion 5 and a second protrusion 6 symmetrically arranged with the first protrusion 5 at one end close to the reagent box 9; the other end of the stirring rod 1 is provided with a magnetic attraction ring 7, the magnetic attraction ring 7 is magnetically connected to a magnet 8, and the magnetic attraction ring 7 is magnetically connected to a magnet 8. The iron 8 is connected to the first driving motor 3; the first driving motor 3 is arranged on one side of the fixed block 10, and the other side of the fixed block 10 is connected to the second driving motor 4 through a transmission module, and the transmission module is arranged on the top of the fixed seat 25; the reagent box 9 is placed directly below the stirring rod 1, and the bottom of the reagent box 9 is connected to a driving base for driving the reagent box 9 to rotate; an inner cavity is provided in the stirring rod 1, and a through hole is provided in the magnet 8, and the inner cavity and the through hole form a cavity 11 for the magnetic rod 2 to pass through; the fixed block 10 is provided with a third driving motor 12 for controlling the up and down displacement of the magnetic rod 2, and the third driving motor 12 is connected to the magnetic rod 2, and the magnetic rod 2 is accommodated in the cavity 11; the third driving motor 12 is arranged parallel to the stirring rod 1. The "stirring rod 1, magnetic rod 2, first drive motor 3 and second drive motor 4" solves the problem of "traditional instruments are easily affected by contamination during use, which is mainly reflected in the number of cleaning times and the loss of nano-magnetic beads during the cleaning process. Too little cleaning will lead to excessive background signals, seriously affecting the accuracy of the detection, while too much cleaning will cause serious loss of magnetic beads, thereby reducing the sensitivity and accuracy of the instrument." The effect of "reducing labor costs, meeting different detection needs, improving sensitivity and accuracy, and achieving the sensitivity and accuracy of traditional chemistry without designing complex pipeline settings and cleaning procedures" is achieved.

[0046] Next, a magnetic bead transfer device for a chemiluminescent immunoassay analyzer in this exemplary embodiment will be further described.

[0047] In an embodiment of the present invention, the magnetic ring 7 can be replaced by a clamping member, and the connection with the first drive motor 3 is achieved through the clamping member, so that the stirring rod is driven by the first drive motor 3.

[0048] In an embodiment of the present invention, the reagent kit 9 ​​is formed by combining a plurality of reagent tubes, that is, there are a plurality of tube positions, wherein the first tube position, the second tube position, and the Nth tube position are arranged in a clockwise direction.

[0049] In one embodiment of the utility model, when it is necessary to transfer magnetic beads, the stirring rod 1 is first lowered to the first tube position of the reagent box 9 by the second drive motor 4 and contacts the liquid in the first tube position, the magnetic rod 2 is lowered together with the stirring rod 1 by the third drive motor 12, and then the driving wheel 13 is driven to rotate by the first drive motor 3, thereby driving the transmission wheel 14 to rotate, the rotation of the transmission wheel 14 drives the magnet 8 to rotate, and the rotation of the magnet 8 drives the stirring rod 1 to rotate, thereby achieving stirring of the liquid, and the first drive motor 3 stops driving after the stirring is completed; when the stirring is completed, since the magnetic rod 2 is in the stirring rod 1, the magnetic beads are adsorbed on the outer wall of the stirring rod 1, and the stirring rod 1 is moved by the second drive motor 4. The stirring rod 1 is moved upwards, and at the same time, the third driving motor 12 also raises the magnetic rod 2 together with the stirring rod 1 until the stirring rod 1 completely leaves the first tube position of the reagent box 9; the reagent box 9 is driven to rotate counterclockwise by the driving base, that is, rotate to the second tube position, and stops when it rotates to the second tube position, that is, the stirring rod 1 is now located directly above the second tube position; and the stirring rod 1 with magnetic beads is lowered into the second tube position of the reagent box 9 by the second driving motor 4 again, and contacts with the liquid in the second tube position, and the magnetic rod 2 is lowered together with the stirring rod 1 with magnetic beads by the third driving motor 12, at this time, the transfer of magnetic beads is completed; it should be noted that when the magnetic beads are transferred from the first tube position to the last tube position, the magnetic beads are no longer transferred in the last tube position.

[0050] In an embodiment of the present invention, the first protrusion 5 and the second protrusion 6 are used to stir the stirring rod 1 when it descends to the pipe position.

[0051] In an embodiment of the present invention, a plurality of different types of reagent kits 9 can be placed on the driving base.

[0052] In one embodiment of the utility model, the stirring rod 1 can be replaced; in a specific implementation, after the processing of the current reagent kit 9 ​​is completed, after the magnetic rod 2 is raised by the third drive motor 12 and the stirring rod 1 is raised by the second drive motor 4, the stirring rod 1 has left the last tube position of the current reagent kit 9, and the magnetic rod 2 continues to be raised by the third drive motor 12. When the bottom of the magnetic rod 2 is raised to be parallel to the bottom of the magnet 8, the third drive motor 12 stops driving. The user can now disassemble the stirring rod 1 and connect the new stirring rod 1 by magnetic attraction. The new stirring rod 1 can be used for the reagent kit 9 ​​to be processed.

[0053] In an embodiment of the present invention, the magnetic bar 2 is used to adsorb magnetic beads formed during the stirring of the liquid, and the magnetic beads are adsorbed on the outer wall of the stirring bar.

[0054] In one embodiment of the utility model, it also includes a gear set, which includes a driving wheel 13 and a transmission wheel 14; the first driving motor 3 is connected to the driving wheel 13, the driving wheel 13 is meshedly connected to the transmission wheel 14, the transmission wheel 14 is connected to the through hole of the magnet 8, and the transmission wheel 14 is provided with a first opening 15 for the magnetic rod 2 to pass through; in a specific embodiment, the driving wheel 13 is driven by the first driving motor 3, the driving wheel 13 drives the transmission wheel 14, and the transmission wheel 14 drives the magnet 8, so that the stirring rod 1 magnetically connected to the magnet 8 rotates, thereby realizing stirring of the liquid in the tube position of the reagent box 9.

[0055] In one embodiment of the utility model, it also includes a first extension member 16 and a second extension member 17; the first drive motor 3 is connected to the driving wheel 13 through the first extension member 16, the first drive motor 3 is arranged at the top of the first extension member 16, the driving wheel 13 is arranged at the bottom of the first extension member 16, the driving wheel 13 and the transmission wheel 14 are both arranged at the top of the second extension member 17, and the transmission wheel 14 is connected to the through hole of the magnet 8 through the second opening of the second extension member 17; one side of the first extension member 16 is fixedly connected to the fixed block 10; one side of the second extension member 17 is fixedly connected to the fixed block 10; in a specific embodiment, the first extension member 16 and the second extension member 17 both play a supporting role.

[0056] In one embodiment of the utility model, it also includes a transmission tube 18, the outer wall of one end of the transmission tube 18 is fixedly connected to the inner wall of the transmission wheel 14, the outer wall of the other end of the transmission tube 18 is fixedly connected to the inner wall of the magnet 8, and the transmission tube 18 passes through the second opening to connect the transmission wheel 14 and the magnet 8 respectively; in a specific embodiment, the transmission tube 18 plays a driving role, that is, when the transmission wheel 14 rotates, the magnet 8 is driven to rotate together through the transmission tube 18.

[0057] In one embodiment of the utility model, the transmission module includes a movable block 19 and a guide rail 20; one side of the movable block 19 is connected to the fixed block 10, and the other side of the movable block 19 is movably connected to the guide rail 20; the movable block 19 is connected to the second drive motor 4; in a specific embodiment, the stirring rod 1 can be raised and lowered by the movable block 19, and the guide rail 20 is used to limit the rising range and the falling range of the stirring rod 1.

[0058] In one embodiment of the utility model, it also includes a positioning detector 21, which is arranged on the fixed block 10, and is arranged in parallel between the positioning detector 21 and the magnetic attraction circle 7; in a specific embodiment, the positioning detector 21 is used to detect whether the magnet 8 is magnetically attracted to the stirring rod 1, that is, to detect whether there is a magnetic attraction circle 7. When the magnetic attraction circle 7 is detected, it means that the stirring rod 1 has been magnetically attracted to the magnet 8; when the magnetic attraction circle 7 is not detected, it means that the magnet 8 is not magnetically connected to the stirring rod 1 at this time; when the magnetic attraction circle 7 is not detected, a prompt message will be issued, and the prompt message such as an alarm sound and flashing lights can remind the user to check in time.

[0059] In one embodiment of the utility model, the driving base includes a carrying fixture 22 and a fourth driving motor 23; the top of the carrying fixture 22 is provided with a receiving groove for placing the reagent kit 9; the bottom of the carrying fixture 22 is connected to the fourth driving motor 23; in a specific embodiment, the fourth driving motor 23 is used to drive the carrying fixture 22 to rotate counterclockwise, thereby realizing the counterclockwise rotation of the reagent kit 9, that is, it can realize the rotation from the first tube position to the Nth tube position.

[0060] In one embodiment of the utility model, a load-bearing base 24 is further included, and the driving base and the fixing base 25 are both arranged on the top of the load-bearing base 24; in a specific embodiment, the load-bearing base 24 plays a stabilizing role.

[0061] In one embodiment of the utility model, a connecting member 26 is further included, one end of the connecting member 26 is connected to the magnetic bar 2, and one end of the connecting member 26 is connected to the third driving motor 12; in a specific embodiment, the connecting member 26 plays a driving role.

[0062] In one embodiment of the utility model, it also includes a power interface 27, and the power interface 27 is electrically connected to the first drive motor 3, the second drive motor 4, the third drive motor 12 and the drive base respectively; in a specific embodiment, the power interface 27 can be used to connect the external power supply to the first drive motor 3, the second drive motor 4, the third drive motor 12 and the drive base respectively, and power supply can be achieved.

[0063] Beneficial effects of the present application: In order to solve the problems existing in traditional chemiluminescence analyzers, a new type of chemiluminescence immunoassay analyzer has been developed. The instrument highly integrates the reagents required for traditional chemistry on the reaction plate. Unlike the traditional cleaning method, the entire process of traditional chemiluminescence is achieved by transferring magnetic beads. This innovation allows the instrument to maintain the advantages of chemiluminescence while abandoning the complex cleaning pipelines and procedures. The advantages of the instrument are mainly reflected in the following aspects:

[0064] First, it does not require regular maintenance and professional operation, which greatly reduces costs and makes it more suitable for use in community health centers and other places. Secondly, by implementing single-person reagents, the scope of application is expanded, avoiding the problem of reagent expiration and waste. In addition, the new instrument has also significantly improved in sensitivity and accuracy, effectively solving the pollution problem of traditional instruments. Overall, it has pushed the chemiluminescence immunoassay analyzer to a new stage of development, providing a more advanced and efficient solution for medical diagnosis.

[0065] The various embodiments in this specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the various embodiments can be referenced to each other.

[0066] Although the preferred embodiments of the present application have been described, those skilled in the art may make additional changes and modifications to these embodiments once they have learned the basic creative concept. Therefore, the appended claims are intended to be interpreted as including the preferred embodiments and all changes and modifications that fall within the scope of the embodiments of the present application.

[0067] Finally, it should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or terminal device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or terminal device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or terminal device including the elements.

[0068] The magnetic bead transfer device for a chemiluminescent immunoassay provided by the present application is introduced in detail above. The principle and implementation mode of the present application are described in detail using specific examples herein. The description of the above embodiments is only used to help understand the method and core idea of ​​the present application. At the same time, for a person skilled in the art, according to the idea of ​​the present application, there may be changes in the specific implementation mode and application scope. In summary, the content of this specification should not be understood as limiting the present application.

Claims

1. A magnetic bead transfer device for a chemiluminescent immunoassay analyzer, characterized in that: It comprises a stirring rod, a magnetic rod, a first driving motor for controlling the rotation of the stirring rod, and a second driving motor for controlling the displacement of the stirring rod; The stirring rod is provided with a first protrusion at one end close to the reagent box and a second protrusion symmetrically arranged with respect to the first protrusion; The other end of the stirring rod is sleeved with a magnetic ring, the magnetic ring is magnetically connected to a magnet, and the magnet is connected to the first drive motor; the first drive motor is arranged on one side of the fixed block, and the other side of the fixed block is connected to the second drive motor through a transmission module, and the transmission module is arranged on the top of the fixed seat; The reagent box is placed directly below the stirring rod, and the bottom of the reagent box is connected to a driving base for driving the reagent box to rotate; An inner cavity is provided in the stirring rod, and a through hole is provided in the magnet. The inner cavity and the through hole form a cavity for the magnetic rod to pass through; the fixed block is provided with a third drive motor for controlling the up and down displacement of the magnetic rod, the third drive motor is connected to the magnetic rod, and the magnetic rod is stored in the cavity; the third drive motor is arranged in parallel with the stirring rod.

2. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 1, characterized in that: Also includes a gear set, the gear set includes a driving wheel and a transmission wheel; The first driving motor is connected to the driving wheel, the driving wheel is meshingly connected to the transmission wheel, the transmission wheel is connected to the through hole of the magnet, and the transmission wheel is provided with a first opening for the magnetic rod to pass through.

3. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 2, characterized in that: Also included is a first extension member and a second extension member; The first driving motor is connected to the driving wheel through the first extension member, the first driving motor is arranged at the top of the first extension member, the driving wheel is arranged at the bottom of the first extension member, the driving wheel and the transmission wheel are both arranged at the top of the second extension member, and the transmission wheel is connected to the through hole of the magnet through the second opening of the second extension member; One side of the first extension piece is fixedly connected to the fixing block; One side of the second extension piece is fixedly connected to the fixing block.

4. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 3, characterized in that: It also includes a transmission tube, the outer wall of one end of the transmission tube is fixedly connected to the inner wall of the transmission wheel, the outer wall of the other end of the transmission tube is fixedly connected to the inner wall of the magnet, and the transmission tube passes through the second opening to connect the transmission wheel and the magnet respectively.

5. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 1, characterized in that: The transmission module includes a movable block and a guide rail; One side of the movable block is connected to the fixed block, and the other side of the movable block is movably connected to the guide rail; the movable block is connected to the second driving motor.

6. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 1, characterized in that: It also includes a positioning detector, which is arranged on the fixed block and is arranged parallel to the magnetic attraction ring.

7. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 1, characterized in that: The driving base includes a bearing fixture and a fourth driving motor; The top of the carrying fixture is provided with a receiving groove for placing the reagent kit; The bottom of the supporting fixture is connected to the fourth driving motor.

8. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 1, characterized in that: It also includes a load-bearing base, and the driving base and the fixing base are both arranged on the top of the load-bearing base.

9. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 1, characterized in that: It also includes a connecting piece, one end of which is connected to the magnetic bar, and one end of which is connected to the third driving motor.

10. The magnetic bead transfer device for chemiluminescent immunoassay analyzer according to claim 1, characterized in that: It also includes a power interface, which is electrically connected to the first drive motor, the second drive motor, the third drive motor and the drive base respectively.

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