In-vitro detection reagent lineation auxiliary calibration mold
By designing an in vitro detection agent line assisted calibration mold that includes the base and calibration department, the problem of direct positioning of the linening line of the NC film preparation is difficult to accurately position, and the higher accuracy and operating efficiency are achieved.
Patent Information
- Application Number
- CN202420964089.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-07
- Publication Date
- 2025-01-28
- Estimated Expiration
- 2034-05-07
AI Technical Summary
In the existing NC film preparation process, the straightness of the marking is difficult to accurately locate, which affects the advantages and disadvantages of later use performance.
A kind of in vitro detection test agent is designed to assist the calibration mold, including the base and the calibration department, align the side of the side of the line with the liner, and position the tank body to slide along the bald ruler, and lock the fixed clamp to ensure the scheming line. Precision positioning of needles.
Improve the accuracy of the positioning of the NC membrane line, reduce the error of the line position, and improve the directability and efficiency of the operation.
Smart Images
Figure CN222405963U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of NC film production, in particular to an in vitro detection reagent marking auxiliary calibration mold. Background Art
[0002] Nitrocellulose filter membrane, referred to as NC membrane, is used as a carrier for quality control lines and antibody lines (i.e., C / T lines) in colloidal gold test paper. It is also the place where immune reactions occur and is one of the most important consumables in biological experiments. NC membrane is generally made of raw nitrocellulose particles, which are dissolved to form a homogenate. The prepared homogenate is then passed through a roller to form a thin film that is spread flat on a smooth flat carrier. After the molding agent in the homogenate is gradually evaporated, it is dried and formed. NC membrane has a strong binding ability to proteins and is suitable for various color development methods, including isotopes, chemiluminescence (Luminous), conventional color development, staining and fluorescence color development; it has low background, high signal-to-noise ratio, is easy to use, and the protein transferred to the NC membrane can be stably stored for a long time under appropriate conditions.
[0003] Sensitivity and resolution are important usage indicators of NC membranes. In addition to being related to factors such as membrane material, membrane purity, and C / T line antibody specificity, they are also related to the manufacturing process of the NC membrane.
[0004] Among them, in the existing NC membrane preparation process, it is necessary to draw lines, that is, the antibody solution diluted to the required concentration is drawn or sprayed on the NC membrane on the operating table. The straightness of the NC membrane drawing determines the quality of the subsequent performance.
[0005] A fixing clip for the marking needle is provided above the operating table of the existing marking machine. The position of the fixing clip can be adjusted left and right with reference to the beam scale above the operating table. However, when the NC film is placed on the operating table and the scale lines on the beam are used as a reference, the position of the line marked by the marking needle on the NC film cannot be accurately located. There is a deviation between the preset position of the marking and the actual position of the marking. Utility Model Content
[0006] In view of this, the utility model provides an auxiliary calibration mold for in vitro detection reagent marking, the main purpose of which is to improve the accuracy of the marking position of the NC film.
[0007] In order to achieve the above purpose, the utility model mainly provides the following technical solutions:
[0008] The utility model provides an in vitro detection reagent marking auxiliary calibration mold, which comprises: a base and a calibration part;
[0009] The side edge of the base overlaps with the side edge of the marking machine operating table;
[0010] The calibration part includes a scale boss and a positioning groove body, the scale boss is fixedly connected to the upper surface of the base, a plurality of scale lines are arranged in sequence in the length direction of the scale boss, the length direction of the scale boss is perpendicular to the side of the marking machine operating table, one end of the positioning groove body is slidably connected to the scale boss, one end of the positioning groove body is provided with a marking line, the marking line corresponds to one of the scale lines, and is used to limit the distance between the positioning groove body and the side of the marking machine operating table.
[0011] The purpose of the utility model and the solution to its technical problems can be further achieved by adopting the following technical measures.
[0012] Optionally, a groove is provided on the lower side of one end of the positioning groove body, the extension direction of the groove is perpendicular to the extension direction of the positioning groove body, and the groove is slidably connected to the scale boss.
[0013] Optionally, the marking line is located on the top wall of the groove, the marking line coincides with the central axis of the positioning groove body, and the top wall of the groove is provided with an observation hole for observing the scale line.
[0014] Optionally, a first threaded hole is provided on a side wall of the groove for threadedly connecting a first positioning pin so that an end of the first positioning pin is pressed against the scale boss.
[0015] Optionally, the observation hole is a waist hole, and the marking line coincides with the central axis of the waist hole in the length direction.
[0016] Optionally, the other end of the positioning slot is provided with an opening.
[0017] Optionally, it also includes a fixing clamp, one end of which is fixedly connected to the edge of the base, the fixing clamp extends along the lower surface of the marking machine operating table, and the fixing clamp is provided with a second threaded hole for threading a second positioning pin so that the end of the second positioning pin is pressed against the marking machine operating table.
[0018] By means of the above technical solution, the utility model has at least the following advantages:
[0019] Before positioning the marking needle, first place the base on the marking machine operating table so that the side of the base is aligned with the side of the marking machine operating table (the scale zero point of the scale line coincides with the side of the marking machine operating table), and then slide the positioning slot along the scale boss so that the marking line at one end of the positioning slot corresponds to the predetermined scale line, so that the distance between the positioning slot and the side of the marking machine operating table is equal to the distance indicated by the predetermined scale line.
[0020] Then, place the fixing clip in the positioning slot and lock the position of the fixing clip on the crossbeam.
[0021] After completing the above operations, the mold is removed from the scribing machine operating table, and then the NC film to be scribed is laid on the upper surface of the scribing machine operating table so that the side of the NC film is aligned with the side of the scribing machine operating table.
[0022] Place the marking needle in the gap of the fixed clamp, and start marking with the marking needle. The distance between the marked line and the side edge of the NC film is equal to the distance indicated by the predetermined scale line.
[0023] During the use of this mold, because the sides of the NC film and the sides of the base are aligned with the sides of the operating table respectively, the position uniformity of the reference objects is improved. On this basis, the locking and fixing clips fix the position of the marking needle in the width direction of the NC film.
[0024] Compared with the traditional method of adjusting the position of the marking needle, the use of this mold is more direct, the error of the NC film marking position is smaller, and the accuracy is higher. BRIEF DESCRIPTION OF THE DRAWINGS
[0025] Figure 1 A stereoscopic image of a first-angle view of an in vitro detection reagent marking auxiliary calibration mold provided by an embodiment of the utility model;
[0026] Figure 2 A stereoscopic image of a second viewing angle of an in vitro detection reagent marking auxiliary calibration mold provided by an embodiment of the utility model;
[0027] Figure 3 A disassembly diagram of an in vitro detection reagent marking auxiliary calibration mold provided in an embodiment of the utility model.
[0028] The figure marks in the drawings of the specification include: base 1, marking machine operating table 2, scale boss 3, positioning slot 4, marking line 5, baffle 6, groove 7, waist hole 8, scale line 9, first threaded hole 10, fixed clamp 11, second threaded hole 12, fixed clamp 13. DETAILED DESCRIPTION
[0029] In order to further explain the technical means and effects adopted by the utility model to achieve the predetermined utility model purpose, the specific implementation methods, structures, features and effects of the utility model application are described in detail below in conjunction with the accompanying drawings and preferred embodiments. In the following description, different "one embodiment" or "embodiment" does not necessarily refer to the same embodiment. In addition, specific features, structures, or characteristics in one or more embodiments may be combined in any suitable form.
[0030] The utility model is further described in detail below in conjunction with the accompanying drawings and embodiments.
[0031] like Figures 1 to 3As shown, an embodiment of the utility model provides an in vitro detection reagent marking auxiliary calibration mold, which includes: a base 1 and a calibration part;
[0032] The side edge of the base 1 overlaps with the side edge of the marking machine operating table 2;
[0033] The calibration part includes a scale boss 3 and a positioning slot 4, the scale boss 3 is fixedly connected to the upper surface of the base 1, a plurality of scale lines 9 are arranged in sequence in the length direction of the scale boss 3, the length direction of the scale boss 3 is perpendicular to the side of the marking machine operating table 2, one end of the positioning slot 4 is slidably connected to the scale boss 3, one end of the positioning slot 4 is provided with a marking line 5, the marking line 5 corresponds to one of the scale lines 9, and is used to limit the distance between the positioning slot 4 and the side of the marking machine operating table 2.
[0034] The working process of the in vitro detection reagent streaking auxiliary calibration mold is as follows:
[0035] Before positioning the marking needle, first place the base 1 on the marking machine operating table 2 so that the side of the base 1 is aligned with the side of the marking machine operating table 2 (the scale zero point of the scale line 9 coincides with the side of the marking machine operating table 2), and then slide the positioning slot 4 along the scale boss 3 so that the marking line 5 at one end of the positioning slot 4 corresponds to the predetermined scale line 9, so that the distance between the positioning slot 4 and the side of the marking machine operating table 2 is equal to the distance indicated by the predetermined scale line 9.
[0036] Then, the fixing clip 13 is placed in the positioning slot 4 and the position of the fixing clip 13 on the crossbeam is locked.
[0037] After completing the above operations, the mold is removed from the scribing machine operating table 2 , and then the NC film to be scribed is laid on the upper surface of the scribing machine operating table 2 , so that the side of the NC film is aligned with the side of the scribing machine operating table 2 .
[0038] The marking needle is placed in the gap of the fixed clip 13 and starts marking a line. The distance between the marked line and the side edge of the NC film is equal to the distance indicated by the predetermined scale line 9 .
[0039] During the use of this mold, because the sides of the NC film and the sides of the base 1 are aligned with the sides of the operating table respectively, the position uniformity of the reference objects is improved. On this basis, the locking and fixing clip 13 fixes the position of the marking needle in the width direction of the NC film.
[0040] In the technical solution of the utility model, compared with the traditional method of adjusting the position of the scribing needle, the use of the present mold is more direct in operation, the error of the NC film scribing position is smaller, and the accuracy is higher.
[0041] Specifically, the side of the marking machine operating platform 2 is fixedly connected to the baffle 6 , and when the side of the base 1 and the side of the marking machine operating platform 2 overlap, the side of the base 1 abuts against the baffle 6 .
[0042] Specifically, the calibration part includes a plurality of positioning grooves 4, one end of each of which is slidably connected to the scale boss 3, so that each of the plurality of positioning grooves 4 positions different fixing clips 13, thereby positioning different marking needles.
[0043] like Figure 3 As shown, in a specific embodiment, a groove 7 is provided on the lower side of one end of the positioning groove body 4 , and the extension direction of the groove 7 is perpendicular to the extension direction of the positioning groove body 4 , and the groove 7 is slidably connected to the scale boss 3 .
[0044] In this embodiment, specifically, the contour of the groove 7 is consistent with the radial contour of the scale boss 3. During the axial sliding of the positioning groove body 4 along the scale boss 3, due to the mutual constraint between the groove 7 and the scale boss 3, the positioning groove body 4 is always perpendicular to the scale boss 3, thereby accurately calibrating the distance between the marking needle fixing clip 13 and the side of the operating table.
[0045] like Figure 1 As shown, in a specific embodiment, the marking line 5 is located on the top wall of the groove 7 , the marking line 5 coincides with the central axis of the positioning groove body 4 , and the top wall of the groove 7 is provided with an observation hole for observing the scale line 9 .
[0046] In this embodiment, specifically, because the marking line 5 coincides with the central axis of the positioning slot 4, when the predetermined scale line 9 is located in the observation hole, the operator can see that the predetermined scale line 9 is aligned with the marking line 5, and at this time the central axis of the positioning slot 4 is aligned with the predetermined scale line 9.
[0047] On the basis of the above, after the fixing clip 13 is placed in the groove of the positioning groove body 4 and locked, the central axis position of the fixing clip 13 (the central axis position is the position of the marking needle) is aligned with the predetermined scale line 9.
[0048] like Figure 1 and Figure 2 As shown, in a specific embodiment, a first threaded hole 10 is provided on the side wall of the groove 7 for threadedly connecting a first positioning pin so that the end of the first positioning pin is pressed against the scale boss 3 .
[0049] In this embodiment, specifically, when the marking line 5 is aligned with the predetermined scale line 9, the first positioning pin is threadedly connected to the first threaded hole 10 so that the first positioning pin is pressed against the scale boss 3, thereby locking the relative position of the positioning groove 4 and the scale boss 3. The effect of this is as follows:
[0050] When the fixing clip 13 is placed in the positioning groove 4, the fixing clip 13 is prevented from moving the positioning groove 4 to change the position of the positioning groove 4 relative to the ruler boss 3, thereby further ensuring the accuracy of the marking position of the marking needle.
[0051] like Figure 1 As shown, in a specific implementation, the observation hole is a waist hole 8, and the marking line 5 coincides with the central axis of the waist hole 8 in the length direction.
[0052] In this embodiment, specifically, the central axis of the waist hole 8 in the length direction coincides with the central axis of the positioning groove 4. When the marking line 5 and the predetermined scale line 9 are aligned, the predetermined scale line 9 is located in the middle position of the length direction of the waist hole 8, which is convenient for the operator to observe and facilitate the operator to clearly identify the marking line 5 and the predetermined scale line 9.
[0053] like Figure 1 As shown, in a specific embodiment, the other end of the positioning slot body 4 is provided with an opening.
[0054] In this embodiment, specifically, after the position of the fixing clip 13 is locked, the operator withdraws the mold horizontally from the operating platform, and at the same time, the fixing clip 13 can be opened from the other end of the positioning groove 4 to cut out the positioning groove 4.
[0055] like Figures 1 to 3 As shown, in a specific embodiment, it also includes a fixing clamp 11, one end of which is fixedly connected to the edge of the base 1, and the fixing clamp 11 extends along the lower surface of the marking machine operating table 2. The fixing clamp 11 is provided with a second threaded hole 12 for threading a second positioning pin so that the end of the second positioning pin is pressed against the marking machine operating table 2.
[0056] In this embodiment, specifically, after the side of the base 1 overlaps with the side of the marking machine operating table 2, the second positioning pin is screwed into the second threaded hole 12, and the end of the second positioning pin is pressed against the lower surface of the marking machine operating table 2, thereby fixing the relative positions of the base 1 and the marking machine operating table 2 and maintaining the parallel relationship between the positioning groove 4 and the side of the marking machine operating table 2.
[0057] The above is only a specific implementation of the utility model, but the protection scope of the utility model is not limited thereto. Any technician familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed by the utility model, which should be included in the protection scope of the utility model. Therefore, the protection scope of the utility model should be based on the protection scope of the claims.
Claims
1. An in vitro detection reagent marking auxiliary calibration mold, characterized in that: include: A base, the side of which coincides with the side of the marking machine operating table; The calibration part includes a scale boss and a positioning groove body, the scale boss is fixedly connected to the upper surface of the base, a plurality of scale lines are arranged in sequence in the length direction of the scale boss, the length direction of the scale boss is perpendicular to the side of the marking machine operating table, one end of the positioning groove body is slidably connected to the scale boss, and one end of the positioning groove body is provided with a marking line, the marking line corresponds to one of the scale lines, and is used to limit the distance between the positioning groove body and the side of the marking machine operating table.
2. The in vitro detection reagent marking auxiliary calibration mold according to claim 1, characterized in that: A groove is provided at the lower side of one end of the positioning groove body, the extension direction of the groove is perpendicular to the extension direction of the positioning groove body, and the groove is slidably connected to the scale boss.
3. The in vitro detection reagent marking auxiliary calibration mold according to claim 2, characterized in that: The marking line is located on the top wall of the groove, the marking line coincides with the central axis of the positioning groove body, and the top wall of the groove is provided with an observation hole for observing the scale line.
4. The in vitro detection reagent marking auxiliary calibration mold according to claim 3, characterized in that: A first threaded hole is provided on the side wall of the groove for threadingly connecting a first positioning pin so that the end of the first positioning pin is tightly pressed against the scale boss.
5. The in vitro detection reagent marking auxiliary calibration mold according to claim 3, characterized in that: The observation hole is a waist hole, and the marking line coincides with the central axis of the waist hole in the length direction.
6. The in vitro detection reagent marking auxiliary calibration mold according to any one of claims 1 to 5, characterized in that: The other end of the positioning slot is provided with an opening.
7. The in vitro detection reagent marking auxiliary calibration mold according to any one of claims 1 to 5, characterized in that: It also includes a fixing clamp, one end of which is fixedly connected to the edge of the base, and the fixing clamp extends along the lower surface of the marking machine operating table. The fixing clamp is provided with a second threaded hole for threading a second positioning pin so that the end of the second positioning pin is pressed against the marking machine operating table.