Y-shaped injector suitable for two components which cannot be premixed

Abstract

The utility model discloses a Y-shaped injector suitable for two components which cannot be premixed, and relates to the technical field of medical instruments. The device structurally comprises a Y-shaped conversion connector and a double-needle-cylinder fixing sleeve. The Y-shaped adapter comprises an output plug used for being matched with a needle head and two injection plugs used for being matched with injector openings. The double-needle-cylinder fixing sleeve comprises two rubber sleeves used for sleeving and fixing an outer cylinder of the injector and a connecting part used for connecting the two rubber sleeves. The Y-shaped adapter and the double-needle-cylinder fixing sleeve are matched with the needle head and the injector, so that the problem that the existing in-situ hydrogel medicine storage depot which is cross-linked too fast can only be implanted in a medicine delivery way is solved, and the whole process from a production end to a use end is sterile; in addition, the Y-shaped double injectors can also be used for injecting two kinds of liquid with the stability or the shape affected by transient mixing, and the stability and the curative effect of transient mixing injection of the medicine are guaranteed.

Description

Technical Field

[0001] The utility model belongs to the technical field of medical instruments, and particularly relates to a Y-shaped syringe suitable for non-premixable double components. Background Art

[0002] Syringe is a commonly used medical device. Currently, commonly used syringes can only be used to deliver one liquid preparation. For preparations containing two different liquid components, mixing in advance will affect each other's stability or cause shape changes. The existing operation method can only be to mix the two liquids on the spot. The operation time and mixing time required for on-site mixing may damage the properties of the two liquids and cause inconvenience to medical staff. Hydrogels are often used as drug reservoirs to play a sustained release role. In order to achieve the purpose of smooth in vivo delivery, the current method is to prepare them into injectable hydrogels and thermosensitive hydrogels. For most polysaccharide materials with good biocompatibility, ion cross-linking is required to form a hydrogel, such as sodium alginate and calcium ions quickly cross-linking to form a hydrogel, which results in that the hydrogel can only deliver drugs by implantation, which is extremely inconvenient, and there is also a risk of bacterial contamination during the implantation process. For this reason, the present application document provides a Y-type syringe suitable for non-premixed two-component for solving the above-mentioned technical problems. Utility Model Content

[0003] The purpose of the utility model is to provide a Y-shaped syringe suitable for non-premixed two-components, which solves the problem that the existing in-situ hydrogel drug reservoir with too fast cross-linking can only be implanted in the administration route by matching the needle and the syringe through a Y-shaped conversion joint and a double syringe fixing sleeve, and realizes full sterility from the production end to the use end.

[0004] In order to solve the above technical problems, the utility model is realized by the following technical solutions:

[0005] The utility model is a Y-type syringe suitable for non-premixed two-components, comprising a Y-type conversion joint and a double syringe fixing sleeve; the Y-type conversion joint comprises an output plug for adapting a needle and two injection plugs for adapting a syringe port; the double syringe fixing sleeve comprises two rubber sleeves for sleeve-fixing the outer barrel of the syringe and a connecting part for connecting the two rubber sleeves.

[0006] As a preferred technical solution of the present utility model, the material of the Y-type conversion joint is polypropylene.

[0007] As a preferred technical solution of the present utility model, the material of the double syringe fixing sleeve is silicone.

[0008] As a preferred technical solution of the utility model, the inner diameter of the rubber sleeve includes at least three specifications of 6.6mm, 10.1mm and 13.4mm, which are respectively used to adapt to 1mL, 2mL and 5mL syringes 4.

[0009] As a preferred technical solution of the utility model, an inner spiral portion is provided on the inner wall of the output plug.

[0010] The utility model has the following beneficial effects:

[0011] 1. The utility model combines a Y-type conversion joint, a double syringe fixing sleeve, a needle and a syringe. When the push rod is pushed at the same time, two liquids will mix at the merging point. The injected mixed liquid forms a hydrogel in situ in a short time, which solves the problem that the existing in situ hydrogel drug reservoir with too fast cross-linking can only be implanted in the administration route, and realizes sterility from the production end to the use end.

[0012] 2. The Y-shaped double syringe of the utility model can also be used for the injection of two liquids whose stability or shape will be affected by short-term mixing, effectively ensuring the stability and efficacy of short-term mixed injection of drugs.

[0013] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0015] Figure 1 The utility model is a schematic structural diagram of a Y-shaped syringe suitable for non-premixable two-component syringes.

[0016] Figure 2 It is a schematic diagram of the structure of a Y-type conversion connector.

[0017] Figure 3 It is a schematic diagram of the structure of the double needle barrel fixing sleeve.

[0018] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0019] 1-Y-type conversion connector, 2-double syringe fixing sleeve, 3-needle, 4-syringe, 101-output plug, 102-injection plug, 201-rubber sleeve, 202-connecting part. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Specific embodiment one:

[0022] See also Figure 1-3 As shown, the utility model is a Y-type syringe suitable for non-premixed two-components, including a Y-type conversion joint 1 and a double syringe fixing sleeve 2. The Y-type conversion joint 1 includes an output plug 101 for adapting to the needle 3 and two injection plugs 102 for adapting to the syringe 4. The double syringe fixing sleeve 2 includes two rubber sleeves 201 for sleeve-fixing the outer barrel of the syringe 4 and a connecting part 202 for connecting the two rubber sleeves 201. Among them, the material of the Y-type conversion joint 1 is polypropylene. Among them, the material of the double syringe fixing sleeve 2 is silicone.

[0023] The inner diameter of the rubber sleeve 201 includes at least three specifications of 6.6 mm, 10.1 mm and 13.4 mm, which are used to adapt to 1 mL, 2 mL and 5 mL syringes 4 respectively.

[0024] In order to increase the mixing uniformity of the liquid injected by the two syringes 4, an inner spiral portion (not shown in the figure) is provided on the inner wall of the output plug 101. The structure of the inner spiral portion is similar to the spiral auger blade. The liquid is output in a spiral state in the output plug 101, and uniform mixing is achieved during the spiral process.

[0025] The two injection plugs 102 of the Y-type conversion connector 1 of the utility model are respectively connected to a syringe 4, and the output plug 101 at the junction is connected to the needle 3. Two liquids that cannot be pre-mixed are respectively stored in the two syringes 4, and the two liquids are mixed at the junction by pushing the push rod at the same time. The inner spiral part of the inner wall of the output plug 101 promotes the mixing uniformity, and passes through the needle 3 at the same time in a mixed state.

[0026] The utility model can be applied to the in-situ formation of a gel drug reservoir. On the one hand, the utility model solves the problem of poor needle permeability caused by the excessively fast cross-linking speed of the two components, so that the combined part and the inside of the needle are both in a liquid state during the injection process, reducing the contact time. This expands the administration method of the drug-loaded sodium alginate hydrogel from implants to injectable preparations. On the other hand, the utility model can also be directly made into a finished drug product, which is in a sterile state from production to use for patients, and has the advantages of easy operation and safety. In addition, this device can also be combined with the currently popular cell therapy to form a hydrogel for sustained-release cells in situ, avoiding mechanical damage to the cells when the injectable hydrogel is passed through the needle. This Y-shaped double syringe has application prospects in both scientific research and clinical practice.

[0027] A specific application of this embodiment is:

[0028] Take the sodium alginate hydrogel cross-linked by calcium ions as an example. This Y-shaped double syringe is used to form a subcutaneous sodium alginate hydrogel drug reservoir. Two 1 mL syringes 4 are respectively filled with equal volumes of 10 mg / mL sodium alginate PBS solution and 5 mg / mL calcium chloride solution, and fixed by a double syringe fixing sleeve 2. At the same time, the push rod is pushed to observe that it has good needle permeability, and the injected mixed liquid forms a hydrogel in a short time.

[0029] The hydrogel reservoir was formed by simulating subcutaneous injection in 6-8 week old C57bl / 6 mice. 100 ul of the above two solutions were injected subcutaneously into the abdomen of the mouse through a Y-shaped syringe. Within 1 minute, a clear bulge was observed at the injection site, and a clear subcutaneous gel reservoir was visible after dissection.

[0030] The utility model solves the problem that the existing in-situ hydrogel drug reservoir with too fast cross-linking can only be implanted in the administration route, and realizes sterility from the production end to the use end. In addition, the utility model Y-shaped double syringe can also be used for the injection of two liquids whose stability or shape will be affected by short mixing.

[0031] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0032] The preferred embodiments of the utility model disclosed above are only used to help explain the utility model. The preferred embodiments do not describe all the details in detail, nor do they limit the utility model to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the utility model, so that technicians in the relevant technical field can well understand and use the utility model. The utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A Y-shaped syringe suitable for non-premixable two-component products, characterized in that: It comprises a Y-type conversion joint (1) and a double syringe fixing sleeve (2); The Y-type conversion connector (1) comprises an output plug (101) for adapting to a needle (3) and two injection plugs (102) for adapting to the ports of a syringe (4); The double syringe fixing sleeve (2) comprises two rubber sleeves (201) for sleeve-fitting and fixing the outer sleeve of the syringe (4) and a connecting portion (202) for connecting the two rubber sleeves (201).

2. The Y-shaped syringe adapted for non-premixable two-component according to claim 1, characterized in that: The material of the Y-shaped conversion joint (1) is polypropylene.

3. The Y-shaped syringe adapted for non-premixable two-component according to claim 1, characterized in that: The material of the double syringe fixing sleeve (2) is silicone.

4. The Y-shaped syringe adapted for non-premixable two-component according to claim 1, characterized in that: The inner diameter of the rubber sleeve (201) includes at least three specifications: 6.6 mm, 10.1 mm and 13.4 mm.

5. The Y-shaped syringe adapted for non-premixable two-component according to claim 1, characterized in that: An inner spiral portion is provided on the inner wall of the output plug (101).

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