Spray drying device for micro-molecular hyaluronic acid

Abstract

The utility model discloses a spray drying device for micro-molecular hyaluronic acid, and relates to the technical field of pharmaceutical engineering. The top end of the base is provided with a preparation tank, a partition plate is fixedly arranged in the preparation tank, the bottom end of the partition plate is fixedly provided with a fixing frame, a rotating shaft is rotationally arranged in the fixing frame, the outer side of the rotating shaft is fixedly provided with a swing frame and a swing plate, and a spray head is arranged in the swing frame; through mutual cooperation of the swing plate, the swing frame, the rotating shaft, the spray head, the first rotating rod and other structures, the spray head can swing in a reciprocating mode, then spray is in full contact with heat in the preparation tank, and then the preparation efficiency can be improved; through mutual cooperation of the second rotating rod, the first scraping plate, the second scraping plate, the discharging opening, the storage box and other structures, particles attached to the inner wall of the preparation tank can be scraped off, then the particles are disassembled into the storage box, and therefore the purpose of convenient cleaning is achieved.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical engineering, in particular to a spray drying device for micromolecular hyaluronic acid. Background Art

[0002] Spray drying of micromolecular hyaluronic acid is a process in which a micromolecular hyaluronic acid liquid solution is sprayed into tiny droplets through a spray injector, and then quickly dried in a hot air flow to transform it into a fine granular solid. The spray drying technology of micromolecular hyaluronic acid is usually used to prepare micromolecular hyaluronic acid products with fine particles.

[0003] However, the existing device has a slow efficiency and poor effect during the preparation process, and many particles often adhere to the inner wall of the preparation tank during the preparation process, which is not convenient for automatic cleaning and collection of the particles. In view of the above problems, the inventor proposes a spray drying device for micromolecular hyaluronic acid to solve the above problems. Utility Model Content

[0004] In order to solve the problems of slow preparation efficiency, poor efficiency and inconvenience in automatic cleaning and collection of particles; the purpose of the utility model is to provide a spray drying device for micromolecular hyaluronic acid.

[0005] In order to solve the above technical problems, the utility model adopts the following technical scheme: a spray drying device for micromolecular hyaluronic acid, comprising a base, a preparation tank is installed on the top of the base, a partition is fixedly provided in the preparation tank, a fixed frame is fixedly provided at the bottom end of the partition, a rotating shaft is rotatably provided in the fixed frame, a swing frame and a swing plate are fixedly provided on the outside of the rotating shaft, a nozzle is installed in the swing frame, a No. 1 rotating rod is rotatably provided in the preparation tank, the No. 1 rotating rod is rotatably inserted in the fixed frame, a fixed plate is fixedly provided on the outside of the No. 1 rotating rod at one end close to the nozzle, a fixed rod is fixedly provided on the end of the fixed plate away from the No. 1 rotating rod, a square groove is opened in the swing plate, and the fixed rod is movably inserted into the square groove.

[0006] Preferably, a No. 2 rotating rod is rotatably inserted into the bottom end of the preparation tank, a No. 1 scraper is fixedly provided on the outside of the No. 2 rotating rod, the No. 1 scraper is fitted with the bottom end of the inner wall of the preparation tank, a No. 2 scraper is fixedly provided on the outside of the No. 1 scraper, the No. 2 scraper is fitted with the side wall of the preparation tank, a discharge port is opened at the bottom end of the preparation tank, and a storage box is installed below the discharge port.

[0007] Preferably, a filter box is installed at the top of the inner wall of the preparation tank, a guide box is fixedly provided on the inner wall of the preparation tank, the guide box is located below the filter box, a heat insulation plate is fixedly provided at the bottom end of the partition, a heating plate mechanism is installed in the preparation tank, the heating plate mechanism is located below the heat insulation plate, a pump body is installed at the top of the partition, a liquid outlet pipe is installed at the input end of the pump body, the liquid outlet pipe is inserted through the guide box, a connecting pipe is fixedly provided at the output end of the pump body, the connecting pipe is inserted through the partition and connected to the nozzle.

[0008] Preferably, a transmission rod is rotatably provided at the bottom end of the preparation tank, a No. 2 bevel gear is fixedly provided at the end of the transmission rod, a No. 1 bevel gear is fixedly sleeved on the outer side of the No. 2 rotating rod, the No. 1 bevel gear and the No. 2 bevel gear are meshed with each other, the transmission rod and the No. 1 rotating rod are connected by a synchronous wheel and a synchronous belt transmission, an L-shaped plate is fixedly provided on the outer side of the preparation tank, a motor is installed on the outer side of the L-shaped plate, and the end of the motor output shaft is inserted into the L-shaped plate and fixedly connected to the No. 1 rotating rod.

[0009] Compared with the prior art, the beneficial effects of the utility model are:

[0010] 1. In the utility model, the structures such as the swing plate, the swing frame, the rotating shaft, the spray head and the No. 1 rotating rod cooperate with each other, so that the spray head can swing back and forth, thereby making the spray fully contact with the heat in the preparation tank, thereby improving the preparation efficiency and preparation efficiency;

[0011] 2. In the utility model, by arranging the No. 2 rotating rod, the No. 1 scraper, the No. 2 scraper, the discharge port and the storage box and other structures to cooperate with each other, the particles attached to the inner wall of the preparation tank can be scraped off, and then the books can be removed and put into the storage box, so as to achieve the purpose of convenient automatic cleaning. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0013] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0014] Figure 2 It is a side schematic diagram of the overall structure of the utility model;

[0015] Figure 3 This is a cross-sectional schematic diagram of the preparation tank and its connection structure of the utility model;

[0016] Figure 4 For this utility model Figure 3 The enlarged structural diagram at A in the middle;

[0017] Figure 5 For this utility model Figure 3 Enlarged structural diagram at B in the middle.

[0018] In the figure: 1. base; 11. preparation tank; 12. filter box; 13. guide box; 14. partition; 15. heat insulation board; 16. storage box; 17. liquid outlet pipe; 18. pump body; 19. connecting pipe; 2. fixed frame; 21. rotating shaft; 22. swing frame; 23. nozzle; 24. swing plate; 25. square groove; 26. rotating rod No. 1; 27. fixed plate; 28. fixed rod; 3. rotating rod No. 2; 31. scraper No. 1; 32. scraper No. 2; 33. discharge port; 34. bevel gear No. 1; 4. transmission rod; 41. bevel gear No. 2; 42. L-shaped plate; 43. motor. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0020] like Figure 1-5 As shown, the utility model provides a spray drying device for micromolecular hyaluronic acid, including a base 1, a preparation tank 11 is installed on the top of the base 1, a partition 14 is fixedly provided in the preparation tank 11, a fixing frame 2 is fixedly provided at the bottom end of the partition 14, a rotating shaft 21 is rotatably provided in the fixing frame 2, a swinging frame 22 and a swinging plate 24 are fixedly provided on the outer side of the rotating shaft 21, the swinging frame 22 swings and drives the nozzle 23 to swing back and forth, so that it can better contact with heat, thereby improving the preparation effect and efficiency, a nozzle 23 is installed in the swinging frame 22, a rotating rod No. 1 26 is rotatably provided in the preparation tank 11, the rotating rod No. 1 26 drives the fixed plate 27 to rotate, the rotating rod No. 1 26 is rotatably inserted in the fixing frame 2, a fixing plate 27 is fixedly provided on the outer side of the rotating rod No. 1 26 at one end close to the nozzle 23, a fixing rod 28 is fixedly provided on the one end of the fixing plate 27 away from the rotating rod No. 1 26, a square groove 25 is opened in the swinging plate 24, and the fixing rod 28 is movably inserted into the square groove 25.

[0021] A No. 2 rotating rod 3 is rotatably inserted in the bottom end of the preparation tank 11, and a No. 1 scraper 31 is fixedly provided on the outside of the No. 2 rotating rod 3. The No. 1 scraper 31 is fitted with the bottom end of the inner wall of the preparation tank 11, and a No. 2 scraper 32 is fixedly provided on the outside of the No. 1 scraper 31. The No. 2 scraper 32 is fitted with the side wall of the preparation tank 11. A discharge port 33 is opened at the bottom end of the preparation tank 11, and a storage box 16 is installed below the discharge port 33.

[0022] By adopting the above technical solution, the No. 2 rotating rod 3 rotates to drive the No. 1 scraper 31 and the No. 2 scraper 32 to rotate, thereby scraping off the particles attached to the inner wall of the preparation tank 11 and transporting them to the storage box 16, thereby achieving the purpose of convenient automatic cleaning and storage.

[0023] A filter box 12 is installed on the top of the inner wall of the preparation tank 11 , and a flow guide box 13 is fixedly provided on the inner wall of the preparation tank 11 . The flow guide box 13 is located below the filter box 12 .

[0024] By adopting the above technical solution, the filter box 12 filters the raw liquid to avoid problems such as blockage of the nozzle 23 caused by large particles.

[0025] A heat insulation board 15 is fixedly provided at the bottom end of the partition 14 , and a heating plate mechanism is installed in the preparation tank 11 , and the heating plate mechanism is located below the heat insulation board 15 .

[0026] By adopting the above technical solution, the heat insulation plate 15 can block the heat, and the heating plate mechanism can heat the inside of the preparation tank 11.

[0027] A pump body 18 is installed at the top of the partition 14, and a liquid outlet pipe 17 is installed at the input end of the pump body 18. The liquid outlet pipe 17 is inserted through the guide box 13, and a connecting pipe 19 is fixedly provided at the output end of the pump body 18. The connecting pipe 19 is inserted through the partition 14 and connected to the nozzle 23.

[0028] By adopting the above technical solution, the pump body 18 transmits the solution to the nozzle 23 , and the solution is sprayed out by the nozzle 23 .

[0029] A transmission rod 4 is rotatably provided at the bottom of the preparation tank 11, a second bevel gear 41 is fixedly provided at the end of the transmission rod 4, a first bevel gear 34 is fixedly sleeved on the outer side of the second rotating rod 3, and the first bevel gear 34 and the second bevel gear 41 are meshed with each other.

[0030] By adopting the above technical solution, the transmission rod 4 rotates to drive the second rotating rod 3 to rotate.

[0031] The transmission rod 4 is connected to the first rotating rod 26 through a synchronous wheel and a synchronous belt transmission.

[0032] By adopting the above technical solution, the first rotating rod 26 rotates to drive the transmission rod 4 to rotate for transmission.

[0033] An L-shaped plate 42 is fixedly provided on the outside of the preparation tank 11 , and a motor 43 is installed on the outside of the L-shaped plate 42 . The end of the output shaft of the motor 43 is inserted through the L-shaped plate 42 and fixedly connected to the first rotating rod 26 .

[0034] By adopting the above technical solution, the output shaft end of the motor 43 rotates to drive the No. 1 rotating rod 26 to rotate, so as to provide power output.

[0035] Working principle: First, the raw liquid is transferred to the filter box 12, and the large particles are filtered through the filter box 12 and transferred to the top of the guide box 13. Then, the pump body 18 is started to make the pump body 18 start working. The pump body 18 transfers the solution to the nozzle 23 through the liquid outlet pipe 17 and the connecting pipe 19. At the same time, the motor 43 is started to make the motor 43 start working. The output shaft end of the motor 43 rotates to drive the No. 1 rotating rod 26 to rotate. The rotation of the No. 1 rotating rod 26 drives the fixed plate 27 to rotate. The rotation of the fixed plate 27 drives the fixed rod 28 to rotate. The fixed rod 28 rotates through the square slot 25 to drive the swing plate 24 to swing back and forth, thereby driving the rotating shaft 21 to rotate back and forth. The rotating shaft 21 drives the swing The frame 22 swings, and the swinging frame 22 swings and can drive the nozzle 23 to swing, so that the spray can contact the heat in the preparation tank 11, thereby improving efficiency and effect. At the same time, the No. 1 rotating rod 26 rotates through the synchronous wheel and the synchronous belt to rotate the transmission rod 4, and the transmission rod 4 rotates to drive the No. 2 bevel gear 41 to rotate, and the No. 2 bevel gear 41 rotates to drive the No. 1 bevel gear 34 to rotate, and the No. 1 bevel gear 34 rotates to drive the No. 2 rotating rod 3 to rotate, and the No. 2 rotating rod 3 rotates to drive the No. 1 scraper 31 and the No. 2 scraper 32 to rotate, so that the particles attached to the inner wall of the preparation tank 11 can be scraped off and transported to the storage box 16, so as to achieve the purpose of convenient automatic cleaning and storage.

[0036] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A spray drying device for micromolecular hyaluronic acid, comprising a base (1), characterized in that: A preparation tank (11) is installed at the top of the base (1), a partition (14) is fixedly provided in the preparation tank (11), a fixing frame (2) is fixedly provided at the bottom end of the partition (14), a rotating shaft (21) is rotatably provided in the fixing frame (2), a swing frame (22) and a swing plate (24) are fixedly provided outside the rotating shaft (21), and a spray head (23) is installed in the swing frame (22); The preparation tank (11) is rotatably provided with a first rotating rod (26), the first rotating rod (26) is rotatably inserted in the fixed frame (2), a fixed plate (27) is fixedly provided at one end of the outer side of the first rotating rod (26) close to the nozzle (23), a fixed rod (28) is fixedly provided at one end of the fixed plate (27) away from the first rotating rod (26), a square groove (25) is opened in the swing plate (24), and the fixed rod (28) is movably inserted through the square groove (25).

2. A spray drying device for micromolecular hyaluronic acid as claimed in claim 1, characterized in that: A second rotating rod (3) is rotatably inserted in the bottom end of the preparation tank (11), and a first scraper (31) is fixedly provided on the outside of the second rotating rod (3). The first scraper (31) is in contact with the bottom end of the inner wall of the preparation tank (11). A second scraper (32) is fixedly provided on the outside of the first scraper (31). The second scraper (32) is in contact with the side wall of the preparation tank (11). A discharge port (33) is provided at the bottom end of the preparation tank (11), and a storage box (16) is installed below the discharge port (33).

3. The spray drying device for micromolecular hyaluronic acid according to claim 1, characterized in that: A filter box (12) is installed at the top of the inner wall of the preparation tank (11), and a flow guide box (13) is fixedly provided on the inner wall of the preparation tank (11), wherein the flow guide box (13) is located below the filter box (12).

4. The spray drying device for micromolecular hyaluronic acid according to claim 1, characterized in that: A heat insulation plate (15) is fixedly provided at the bottom end of the partition (14), and a heating plate mechanism is installed in the preparation tank (11), and the heating plate mechanism is located below the heat insulation plate (15).

5. The spray drying device for micromolecular hyaluronic acid according to claim 1, characterized in that: A pump body (18) is installed at the top of the partition (14); a liquid outlet pipe (17) is installed at the input end of the pump body (18); the liquid outlet pipe (17) is inserted through the guide box (13); a connecting pipe (19) is fixedly provided at the output end of the pump body (18); the connecting pipe (19) is inserted through the partition (14) and connected to the nozzle (23).

6. The spray drying device for micromolecular hyaluronic acid according to claim 2, characterized in that: A transmission rod (4) is rotatably provided at the bottom end of the preparation tank (11), a second bevel gear (41) is fixedly provided at the end of the transmission rod (4), a first bevel gear (34) is fixedly sleeved on the outer side of the second rotating rod (3), and the first bevel gear (34) and the second bevel gear (41) are meshed with each other.

7. The spray drying device for micromolecular hyaluronic acid according to claim 6, characterized in that: The transmission rod (4) is connected to the first rotating rod (26) through a synchronous wheel and a synchronous belt transmission.

8. The spray drying device for micromolecular hyaluronic acid according to claim 1, characterized in that: An L-shaped plate (42) is fixedly provided on the outside of the preparation tank (11), a motor (43) is installed on the outside of the L-shaped plate (42), and the end of the output shaft of the motor (43) is inserted through the L-shaped plate (42) and fixedly connected to the first rotating rod (26).

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