Sand-core-free column body reinforced detachable chromatographic column

Abstract

The utility model discloses a detachable chromatographic column reinforced by a column body without a sand core, and relates to the related technical field of chromatographic equipment. The chromatographic column comprises a chromatographic column main body, a reinforcing sleeve and a supporting disc, the reinforcing sleeve is fixedly communicated with the bottom end of the chromatographic column main body, the supporting disc is fixed on the peripheral side of the reinforcing sleeve, a rotating sleeve is movably connected to the edge of the outer side of the supporting disc, supporting legs are fixed at the bottom end of the rotating sleeve in an annular array, and a reinforcing metal net is fixed in the reinforcing sleeve. Through the arrangement of the chromatographic column main body, the reinforcing sleeve and the supporting disc, the problems that the piston part and the liquid outlet pipe of the chromatographic column are easy to break, the use range is limited, the liquid separation efficiency is low, and the direction of a switch handle is inconvenient to change by a piston at the bottom of the chromatographic column are solved; the utility model has the advantages that the piston part of the chromatographic column and the liquid outlet pipe are firmer, the application range is wider, the liquid separation efficiency is higher, and the piston at the bottom of the chromatographic column can change the direction of the switch handle more conveniently.

Description

Technical Field

[0001] The utility model belongs to the technical field related to chromatography equipment, and particularly relates to a detachable chromatography column reinforced with a sand-free column. Background Art

[0002] In the early days, people invented funnels to separate liquids or solids from mixtures. In the early 19th century, funnels gradually took their initial shape. In early chemical experiments, funnels became a practical tool for separating and purifying substances, but funnels were not suitable for separating large quantities of substances. As time went on, chromatography technology was proposed, which can efficiently separate substances with similar properties. As a result, chromatography columns were invented for separating, purifying, and analyzing mixtures. Chromatography columns come in a variety of specifications. Small chromatography columns can be used in basic experiments, and large chromatography columns can be used to separate large quantities of substances in industry, solving the defects of funnels. However, it still has the following disadvantages in actual use:

[0003] Chromatographic columns are used to separate and purify various substances. The columns used must meet the requirements of corrosion resistance, high / low temperature resistance, and not easy to damage. Currently, the chromatography columns on the market can meet the requirements of corrosion resistance and high / low temperature resistance. However, the piston part and the liquid outlet pipe of the chromatography column are easy to break during use, which not only reduces the service life of the entire chromatography column, but also has certain safety issues. Although some chromatography columns with sand cores speed up the separation rate of substances, their use range is limited and the liquid separation efficiency is not high. They are generally used for simple chromatography experiments;

[0004] During the experiment of separation and purification of the chromatography column, the angle of the bottom piston is fixed. After being supported on the experimental platform by its external bracket, it needs to be rotated as a whole so that the bottom piston can move to the appropriate opening direction to match different liquid outlet settings. It is not convenient to carry the chromatography column and the bracket as a whole during operation. Utility Model Content

[0005] The utility model aims to provide a detachable chromatography column reinforced with a sand core-free column body. By arranging a chromatography column body, a reinforcement sleeve and a support plate, the utility model solves the problems that the piston part and the liquid outlet pipe of the chromatography column are easy to break, the scope of use is limited, the liquid separation efficiency is low, and it is inconvenient to change the direction of the switch handle of the piston at the bottom of the chromatography column.

[0006] In order to solve the above technical problems, the utility model is realized by the following technical solutions:

[0007] The utility model discloses a detachable chromatography column reinforced with a sand core-free column, comprising a chromatography column body, a reinforcement sleeve and a support plate, wherein the bottom end of the chromatography column body is fixedly connected with the reinforcement sleeve, the peripheral side of the reinforcement sleeve is fixed with the support plate, the outer edge of the support plate is movably connected with a rotating sleeve, the bottom end of the rotating sleeve is fixed with support legs in a circular array, a reinforced metal mesh is fixed in the reinforcement sleeve, and during operation, the chromatography column body is used to perform chromatography on the material, the chromatographic material in the chromatography column body is transported to a concentration port through the reinforcement sleeve, and the support plate is fixed to the peripheral side of the reinforcement sleeve, so that the support legs at the bottom end of the rotating sleeve outside the support plate are supported on the ground.

[0008] Furthermore, the top of the chromatography column body is fixedly connected with an opening, a frosted ring is fixed at the top of the opening, and fillers and liquids to be chromatographed are input into the chromatography column body through the opening.

[0009] Furthermore, the bottom end of the reinforcement sleeve is fixedly connected to a central port, the bottom end of the central port is fixedly connected to a transfer tube, and reinforced metal meshes are fixed in the central port and the transfer tube. The reinforcement sleeve concentrates the materials transported therein through the central port, and transfers the materials therein to the polytetrafluoroethylene three-way piston through the transfer tube.

[0010] Furthermore, the support plate is provided with a fixing opening along the central axis, the reinforcement sleeve is fixed in the fixing opening, and the support plate is fixed to the peripheral side of the reinforcement sleeve through the fixing opening.

[0011] Furthermore, the bottom end of the transfer tube is fixedly connected to a tetrafluoro three-way piston, and the bottom end of the tetrafluoro three-way piston is fixedly connected to a threaded ring. The transfer tube controls the on-off of conveying materials through the tetrafluoro three-way piston, and the spiral interface is threadedly connected therein through the threaded ring.

[0012] Furthermore, a bottom liquid outlet pipe is arranged below the tetrafluoro three-way piston, the top end of the bottom liquid outlet pipe is fixedly connected with a liquid outlet pipe spiral interface, the liquid outlet pipe spiral interface is threadedly connected in a threaded ring, the diameter of the bottom liquid outlet pipe is equal to the diameter of the threaded ring, and the tetrafluoro three-way piston outputs the material after chromatography through the bottom liquid outlet pipe.

[0013] The utility model has the following beneficial effects:

[0014] The utility model solves the problems of easy breakage of the piston part and the liquid outlet pipe of the chromatography column, limited use range and low liquid separation efficiency by arranging the chromatography column main body and the reinforcement sleeve. The reinforcement sleeve at the bottom end of the chromatography column, the central port and the transfer tube are added with a steel wire reinforcement component to prevent the lower part of the chromatography column to the upper part of the liquid outlet pipe from being broken due to high temperature or external force when chromatographing overheated substances; the chromatography column does not include a sand core, so that the experimental range is wider; the bottom liquid outlet pipe is separately designed as a detachable part, which is convenient for real-time replacement, thereby extending the service life of the chromatography column.

[0015] The utility model solves the problem of inconvenience in changing the direction of the switch handle of the piston at the bottom of the chromatography column by arranging the chromatography column main body and the reinforcement sleeve. The rotating sleeve is supported on the work surface by the supporting legs, and the supporting plate is supported on the work surface by the supporting legs through the rotating sleeve, so that the reinforcement sleeve and the chromatography column main body are well supported, and the reinforcement sleeve and the chromatography column main body can rotate relative to the rotating sleeve, thereby changing the position of the tetrafluoro three-way piston, making the tetrafluoro three-way piston more convenient to switch. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions of the embodiments of the utility model, the drawings required for describing the embodiments are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0017] Figure 1 A three-dimensional diagram of the assembly structure of a detachable chromatography column reinforced with a sand core-free column;

[0018] Figure 2 It is a three-dimensional diagram of the main structure of the chromatography column;

[0019] Figure 3 It is a three-dimensional diagram of the reinforcement sleeve structure;

[0020] Figure 4 It is a three-dimensional diagram of the support plate structure;

[0021] Figure 5 This is a three-dimensional diagram of the PTFE three-way piston structure;

[0022] Figure 6 It is a three-dimensional diagram of the bottom liquid outlet pipe structure.

[0023] Reference numerals:

[0024] 1. Chromatography column body; 101. Open end; 102. Frosted ring; 2. Reinforcement sleeve; 201. Centralizing port; 202. Transfer tube; 203. Reinforced metal mesh; 3. Support plate; 301. Rotating sleeve; 302. Support leg; 303. Fixed port; 4. PTFE three-way piston; 401. Threaded ring; 5. Bottom liquid outlet pipe; 501. Liquid outlet pipe spiral interface. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model. Specific embodiment 1

[0026] See also Figure 1-6 The utility model is a detachable chromatography column reinforced with a sand core-free column, comprising a chromatography column body 1, a reinforcement sleeve 2 and a support plate 3. The bottom end of the chromatography column body 1 is fixedly connected with the reinforcement sleeve 2. The chromatography column body 1 contains the chromatography filler therein for chromatography operation, and the chromatographic filler in the chromatography column body 1 is output through the reinforcement sleeve 2. The support plate 3 is fixed on the peripheral side of the reinforcement sleeve 2, and the support plate 3 supports the reinforcement sleeve 2 thereon. The outer edge of the support plate 3 is movably connected with a rotating sleeve 301, and the support plate 3 is movably connected thereto through the rotating sleeve 301. The rotating sleeve 3 The bottom end of 01 is fixed with supporting legs 302 in a circular array, and the rotating sleeve 301 is supported on the work surface by the supporting legs 302. The supporting plate 3 is supported on the work surface by the supporting legs 302 through the rotating sleeve 301, so that the reinforcement sleeve 2 and the chromatography column body 1 are well supported, and the reinforcement sleeve 2 and the chromatography column body 1 can rotate relative to the rotating sleeve 301, changing the position of the tetrafluoro three-way piston 4, so that the tetrafluoro three-way piston 4 can be more convenient for switching operations. A reinforcing metal mesh 203 is fixed in the reinforcement sleeve 2, and the reinforcement sleeve 2 is reinforced by the reinforcing metal mesh 203.

[0027] Specifically, the top of the chromatography column body 1 is fixedly connected to an opening 101, and a frosted ring 102 is fixed to the top of the opening 101. The chromatography column body 1 contains fillers and chromatography liquids through the opening 101 for chromatography, and the frosted ring 102 supports the equipment for the liquid output by the chromatography, so that the liquid to be chromatographed is input into the chromatography column body 1.

[0028] Furthermore, the bottom end of the reinforcement sleeve 2 is fixedly connected to a concentration port 201, and the bottom end of the concentration port 201 is fixedly connected to a transfer tube 202. A reinforcement metal mesh 203 is fixed in both the concentration port 201 and the transfer tube 202. The reinforcement sleeve 2 concentrates the chromatographic material in the chromatography column body 1 into the transfer tube 202 through the concentration port 201, and outputs the concentrated material in the concentration port 201 to the polytetrafluoroethylene three-way piston 4 through the transfer tube 202. The reinforcement sleeve 2, the concentration port 201 and the transfer tube 202 are strengthened by the reinforcement metal mesh 203 to prevent the reinforcement sleeve 2, the concentration port 201 and the transfer tube 202 from being damaged.

[0029] The operation process of this embodiment is as follows: when working, the chromatography column body 1 contains the filler and the chromatography liquid therein through the open port 101 for chromatography, and supports the equipment of the chromatography output liquid through the frosted ring 102, so that the liquid to be chromatographed is input into the chromatography column body 1 for chromatography. After chromatography, the reinforcement sleeve 2 collects the chromatographed materials in the chromatography column body 1 into the transfer tube 202 through the collection port 201, and outputs the collected materials in the collection port 201 into the tetrafluoro three-way piston 4 through the transfer tube 202. The rotating sleeve 301 is supported on the workbench by the supporting legs 302, and the supporting plate 3 is supported on the workbench by the supporting legs 302 through the rotating sleeve 301, so that the reinforcement sleeve 2 and the chromatography column body 1 are well supported, and the reinforcement sleeve 2 and the chromatography column body 1 can rotate relative to the rotating sleeve 301, thereby changing the position of the tetrafluoro three-way piston 4, so that the tetrafluoro three-way piston 4 can be more conveniently opened and closed. Specific embodiment 2

[0030] See also Figure 1 , 3 , 5, 6, on the basis of the specific embodiment 1, the support plate 3 is provided with a fixing opening 303 along the central axis, the reinforcement sleeve 2 is fixed in the fixing opening 303, and the support plate 3 fixes the reinforcement sleeve 2 through the fixing opening 303, so that the reinforcement sleeve 2 and the chromatography column body 1 are supported on the work surface through the support legs 302 at the bottom end of the rotating sleeve 301 outside the support plate 3.

[0031] Specifically, the bottom end of the transfer tube 202 is fixedly connected to a tetrafluoro three-way piston 4, and the bottom end of the tetrafluoro three-way piston 4 is fixedly connected to a threaded ring 401. The transfer tube 202 controls the on-off of the material conveyed therein through the tetrafluoro three-way piston 4, and the tetrafluoro three-way piston 4 is threadedly connected to the bottom liquid outlet pipe 5 through the threaded ring 401.

[0032] Furthermore, a bottom liquid outlet pipe 5 is arranged below the polyfluoro three-way piston 4, and the top of the bottom liquid outlet pipe 5 is fixedly connected to a liquid outlet pipe spiral interface 501, and the liquid outlet pipe spiral interface 501 is threadedly connected in the threaded ring 401. The diameter of the bottom liquid outlet pipe 5 is equal to the diameter of the threaded ring 401. The polyfluoro three-way piston 4 outputs the material transferred in the polyfluoro three-way piston 4 to the bottom liquid outlet pipe 5 through the bottom liquid outlet pipe 5. After the bottom liquid outlet pipe 5 is screwed into the threaded ring 401 through the liquid outlet pipe spiral interface 501 at its top, the bottom liquid outlet pipe 5 is connected to the bottom end of the polyfluoro three-way piston 4.

[0033] The operation process of this embodiment is as follows: during operation, the reinforcement sleeve 2, the central port 201 and the transfer tube 202 are strengthened by the reinforcement metal mesh 203 to prevent the reinforcement sleeve 2, the central port 201 and the transfer tube 202 from being damaged; the fluorine three-way piston outputs the transferred material in the tetrafluoro three-way piston 4 to the bottom liquid outlet pipe 5 through the bottom liquid outlet pipe 5; after the bottom liquid outlet pipe 5 is screwed into the threaded ring 401 through the liquid outlet pipe spiral interface 501 at its top, the bottom liquid outlet pipe 5 is connected to the bottom end of the tetrafluoro three-way piston 4, so that during operation, the bottom liquid outlet pipe 5 can be separated from the tetrafluoro three-way piston 4.

[0034] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0035] The preferred embodiments of the utility model disclosed above are only used to help explain the utility model. The preferred embodiments do not describe all the details in detail, nor do they limit the utility model to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the utility model, so that technicians in the relevant technical field can well understand and use the utility model. The utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A detachable chromatography column without sand core column reinforcement, comprising a chromatography column body (1), a reinforcement sleeve (2) and a support plate (3), characterized in that: The bottom end of the chromatography column body (1) is fixedly connected to a reinforcement sleeve (2), a support plate (3) is fixed to the circumference of the reinforcement sleeve (2), a rotating sleeve (301) is movably connected to the outer edge of the support plate (3), support legs (302) are fixed to the bottom end of the rotating sleeve (301) in a circular array, and a reinforcement metal mesh (203) is fixed inside the reinforcement sleeve (2).

2. A sand-core-free column reinforced removable chromatography column according to claim 1, characterized in that: The top of the chromatography column body (1) is fixedly connected to an opening (101), and the top of the opening (101) is fixed with a frosted ring (102).

3. A sand-core-free column reinforced removable chromatography column according to claim 1, characterized in that: The bottom end of the reinforcement sleeve (2) is fixedly connected to a central port (201), the bottom end of the central port (201) is fixedly connected to a transfer tube (202), and a reinforcement metal mesh (203) is fixed inside both the central port (201) and the transfer tube (202).

4. The non-sand core column reinforced removable chromatography column according to claim 1, characterized in that: The support plate (3) is provided with a fixing opening (303) along the central axis, and the reinforcement sleeve (2) is fixed in the fixing opening (303).

5. The non-sand core column reinforced removable chromatography column according to claim 3, characterized in that: The bottom end of the transfer tube (202) is fixedly connected to a tetrafluoro three-way piston (4), and the bottom end of the tetrafluoro three-way piston (4) is fixedly connected to a threaded ring (401).

6. A sand-core-free column reinforced removable chromatography column according to claim 5, characterized in that: A bottom liquid outlet pipe (5) is arranged below the tetrafluoro three-way piston (4); the top end of the bottom liquid outlet pipe (5) is fixedly connected to a liquid outlet pipe spiral interface (501); the liquid outlet pipe spiral interface (501) is threadedly connected in a threaded ring (401); and the diameter of the bottom liquid outlet pipe (5) is equal to the diameter of the threaded ring (401).

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