Centrifugal machine for cell experiment

By using the lifting mechanism and groove design in the centrifuge, the problem of cell fluid contamination caused by finger contacting the test tube mouth after centrifugation is solved, achieving higher accuracy of experimental results.

CN222469359UActive Publication Date: 2025-02-14AFFILIATED HOSPITAL OF GUANGDONG MEDICAL UNIV
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Patent Information

Application Number
CN202421236280.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-31
Publication Date
2025-02-14
Estimated Expiration
2034-05-31

AI Technical Summary

Technical Problem

After the centrifuge is completed, the experimenter will easily lead to cell fluid contamination when holding the test tube mouth with his hands, affecting the experimental results.

Method used

A centrifuge for cell experiments was designed, using a combination of lifting mechanism and grooves to automatically extract the test tubes through the lifting mechanism, and the grooves were used to reduce the chance of fingers touching the test tube mouth and reduce the risk of cell fluid contamination.

Benefits of technology

It effectively reduces the chance of fingers contacting the test tube mouth, reduces the risk of cell fluid contamination, and improves the accuracy of experimental results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a centrifugal machine for cell experiments, which relates to the technical field of centrifugal machines and comprises an outer shell, a connecting block is fixedly connected to the rear end of the outer shell, centrifugal machine covers are rotatably connected to two ends of the connecting block, and a centrifugal groove is formed in the center of the upper end of the outer shell. A centrifugal mechanism is arranged in the center of the bottom end in the centrifugal groove, a plurality of fixing grooves are formed in the periphery of the bottom end in the centrifugal groove, lifting mechanisms are arranged in the fixing grooves, a display screen is arranged at the upper end of the outer surface of the front end of the outer shell, and a switch button is arranged at the lower end of the outer surface of the front end of the outer shell. An adjusting knob is arranged on the left side of the switch button. Through the lifting mechanism and the groove, when a plurality of test tubes are extracted at the same time or a single test tube is extracted, the risk that cell sap in the test tubes is polluted due to the fact that fingers make contact with test tube openings can be effectively reduced, the practicability of the centrifugal machine is improved, and the experiment accuracy is effectively improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of centrifuges, in particular to a centrifuge used for cell experiments. Background Art

[0002] Centrifugation technology is one of the most commonly used methods for separating proteins, enzymes, nucleic acids and cell subcomponents. It uses the strong centrifugal force generated by the high-speed rotation of an object to cause the suspended particles placed in the rotating body to settle or float, so that some particles can be concentrated or separated from other particles. Most of the existing centrifuges require experimenters to take the test tube mouth by hand to extract the test tube after centrifugation, which is easy to cause cell fluid contamination in the test tube. For example, a centrifuge for cell experiments recorded in the patent announcement number CN 217411114 U includes a body, a placement tray and a base, the inner bottom wall of the body is installed with a placement tray, the inner wall of the placement tray is provided with multiple groups of embedded holes, the inner wall of the embedded hole is installed with a soft pad, the inner wall of the embedded hole is installed with an air bag, the inner wall of the placement tray is installed with a No. 1 motor, and the bottom of the spring plug is installed with a toothed plate. The above-mentioned comparative documents install an air bag, put the reagent tube into the embedded hole of the placement plate, and the air bag swells, so that the reagent tube is clamped by the soft cushion and the air bag. When rotating the centrifuge, the reagent tube and the placement plate will not shake, making it difficult for the reagent tube to be hit and damaged by the placement plate. However, when extracting the test tube after centrifugation, fingers directly touching the test tube mouth can easily cause contamination of the cell separation solution, resulting in deviations in experimental results.

[0003] Based on this, a centrifuge for cell experiments is now provided, which can effectively reduce the risk of cell fluid contamination caused by contact between fingers and the mouth of the test tube when taking the cell fluid after centrifugation is completed. Utility Model Content

[0004] The utility model aims to provide a centrifuge for cell experiments to solve the problem that the experimenter takes the mouth of the test tube by hand to extract the test tube, which easily causes the cell fluid in the test tube to be contaminated.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A centrifuge for cell experiments comprises an outer shell, a connecting block is fixedly connected to the rear end of the outer shell, centrifuge covers are rotatably connected to the two ends of the connecting block, a centrifuge groove is provided at the center of the upper end of the outer shell, a centrifuge mechanism is provided at the center of the bottom end of the centrifuge groove, a plurality of fixed grooves are provided around the bottom end of the centrifuge groove, a lifting mechanism is provided in the fixed grooves, a display screen is provided at the upper end of the front end outer surface of the outer shell, a switch button is provided at the lower end of the front end outer surface of the outer shell, and an adjusting knob is provided on the left side of the switch button.

[0007] On the basis of the above technical solutions, the present invention also provides the following optional technical solutions:

[0008] In an optional scheme: a centrifuge for cell experiments according to the claim, characterized in that the centrifugal mechanism includes a motor fixedly connected to the center position of the bottom end of the centrifugal tank, a rotating shaft is provided at the output end of the motor, a cross connecting plate is fixedly connected to the upper end of the rotating shaft, a placement plate is provided on the side of the cross connecting plate away from the rotating shaft, a limiting groove is provided at the center position of the mounting surface of the placement plate, the upper end of the cross connecting plate is inserted into the limiting groove, the size of the limiting groove is the same as that of the cross connecting plate, and a plurality of placement holes are provided at the upper end of the placement plate.

[0009] In an optional solution: the lifting mechanism includes a telescopic rod fixedly connected to the center position inside the fixed groove, the output end of the telescopic rod is fixedly connected to the surrounding positions of the lower end of the lifting plate, and a slot is opened in the middle position of the lifting plate, and the size of the slot is the same as the size of the motor.

[0010] In an optional solution: a plurality of test tube slots are arranged around the upper end of the lifting plate.

[0011] In an optional solution: a groove is provided on the upper end surface of the outer shell, and the groove is located on the left and right sides of the upper end of the centrifugal groove.

[0012] In an optional solution: a rubber anti-slip coating is provided inside the placement hole.

[0013] In an optional solution: a plurality of suction cups are arranged at the outer bottom end of the outer shell.

[0014] In an optional solution: a transverse anti-slip groove is provided on the outer side surface of the placement board.

[0015] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0016] The utility model can effectively reduce the risk of contamination of cell fluid inside the test tubes due to contact of fingers with the test tube openings, whether extracting from multiple test tubes at the same time or extracting from a single test tube, by means of the lifting mechanism and the groove. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall front structure of the utility model.

[0018] Figure 2 It is a schematic diagram of the cross-sectional structure of the overall front side of the utility model.

[0019] Figure 3 It is a structural schematic diagram of the centrifugal mechanism of the utility model.

[0020] Figure 4 It is a schematic diagram of the overall structure of the utility model from a top view.

[0021] Figure 5 It is a schematic structural diagram of an overall oblique section of the utility model.

[0022] Notes on the accompanying drawings: 1. outer shell; 2. connecting block; 3. centrifuge cover; 4. centrifugal tank; 5. centrifugal mechanism; 51. motor; 52. rotating shaft; 53. cross connecting plate; 54. limiting groove; 55. placement plate; 56. placement hole; 6. fixing groove; 7. lifting mechanism; 71. telescopic rod; 72. lifting plate; 73. slot; 8. display screen; 9. switch button; 10. adjustment knob; 11. test tube slot; 12. groove; 13. suction cup. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments.

[0024] Example 1

[0025] In one embodiment, Figure 1-Figure 5 As shown, a centrifuge for cell experiments comprises an outer shell 1, a connecting block 2 is fixedly connected to the rear end of the outer shell 1, and centrifuge covers 3 are rotatably connected to both ends of the connecting block 2. A centrifuge groove 4 is provided at the center of the upper end of the outer shell 1, a centrifuge mechanism 5 is provided at the center of the bottom end of the inner part of the centrifuge groove 4, a plurality of fixed grooves 6 are provided around the bottom end of the inner part of the centrifuge groove 4, a lifting mechanism 7 is provided in the fixed groove 6, and a plurality of suction cups 13 are provided at the outer bottom end of the outer shell 1. When performing cell centrifugation operation, the centrifuge can be fixed on a plane as a whole, which is more stable. A display screen 8 is provided at the upper end of the front outer surface of the outer shell 1, and a user can observe the remaining centrifugation time in real time through the display screen 8. A switch button 9 is provided at the lower end of the front outer surface of the outer shell 1, and an adjusting knob 10 is provided on the left side of the switch button 9. The user can adjust the centrifugation time by rotating the adjusting knob 10 as needed, which is more practical.

[0026] In one embodiment, Figure 2As shown, the centrifugal mechanism 5 includes a motor 51 fixedly connected to the center position of the bottom end of the centrifugal tank 4, a rotating shaft 52 is arranged at the output end of the motor 51, a cross connecting plate 53 is fixedly connected to the upper end of the rotating shaft 52, a placing plate 55 is arranged on the side of the cross connecting plate 53 away from the rotating shaft 32, a limiting groove 54 is arranged at the center position of the mounting surface of the placing plate 55, and the size of the limiting groove 54 is the same as that of the cross connecting plate 53, and a plurality of placing holes 56 are arranged at the upper end of the placing plate 55. When the user needs to centrifuge the cell fluid, the motor 51 is turned on, and the motor 51 drives the cross connecting plate 53 installed above the rotating shaft 52 to rotate, and the cross connecting plate 55 is arranged on the side of the cross connecting plate 53 away from the rotating shaft 32. The connecting plate 53 is inserted into the limiting groove 54, driving the placement plate 55 to rotate together, and the test tube is placed in the placement hole 56. The cell fluid in the test tube successfully completes the separation purpose. A groove 12 is provided on the upper end surface of the outer shell 1. The groove 12 is located on the left and right sides of the upper end of the centrifugal tank 4. A transverse anti-skid groove is provided on the outer surface of the placement plate 55. After the centrifugation is completed, the user can conveniently take out the placement plate 55 together with the test tube for subsequent observation operations to prevent contamination caused by contact with the test tube mouth when taking it. A rubber anti-skid coating is provided inside the placement hole 56 to prevent the test tube from sliding relative to each other during the centrifugation process, thereby causing incomplete centrifugation.

[0027] Example 2

[0028] In one embodiment, Figure 2 and Figure 3 As shown, the lifting mechanism 7 includes a telescopic rod 71 fixedly connected to the center position inside the fixed groove 6, the output end of the telescopic rod 71 is fixedly connected to the surrounding positions of the lower end of the lifting plate 72, and a slot 73 is provided in the middle position of the lifting plate 72. The size of the slot 73 is the same as the size of the motor 51. A plurality of test tube slots 11 are arranged around the upper end of the lifting plate 72. When some cell fluid test tubes in the centrifuge have completed centrifugation, but some test tubes have not completed centrifugation, the telescopic rod 71 is stretched to drive the lifting plate 72 to rise, and the test tubes that have completed centrifugation can be taken out. At this time, the telescopic rod 71 is contracted to drive the lifting plate 72 to descend, and the test tubes that have not completed centrifugation are sent back into the centrifuge to continue the centrifugation operation. Lifting and taking out the test tubes can effectively prevent cell fluid contamination caused by contact with the test tube mouth when taking them out.

[0029] The above embodiment discloses a centrifuge for cell experiments, wherein when the user needs to centrifuge the cell fluid, the suction cup 13 is first used to fix the centrifuge as a whole on a plane, which is more stable, and then the motor 51 is turned on, the motor 51 drives the cross connecting plate 53 installed above the rotating shaft 52 to rotate, the cross connecting plate 53 is inserted into the limiting groove 54, and drives the placement plate 55 to rotate together, and the test tube is placed in the placement hole 56. The cell fluid in the test tube successfully completes the separation purpose, and the groove 12 for convenient finger placement can facilitate the user to place the test tube after the centrifugation is completed. The placement plate 55 is taken out together with the test tube for subsequent observation operations to prevent contamination caused by contact with the test tube mouth when taking it out. When some cell fluid test tubes in the centrifuge have completed centrifugation, but some test tubes have not completed centrifugation, the telescopic rod 71 is stretched to drive the lifting plate 72 to rise, and the test tubes that have completed centrifugation can be taken out. At this time, the telescopic rod 71 is retracted to drive the lifting plate 72 to descend, and the test tubes that have not completed centrifugation are sent back into the centrifuge to continue the centrifugation operation. Lifting the test tube and taking it out can effectively reduce the risk of cell fluid contamination caused by contact with the test tube mouth when taking it out.

[0030] The above is only a specific implementation of the present disclosure, but the protection scope of the present disclosure is not limited thereto. Any person skilled in the art who is familiar with the technical field can easily think of changes or substitutions within the technical scope disclosed in the present disclosure, which should be included in the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure should be based on the protection scope of the claims.

Claims

1. A centrifuge for cell experiments, comprising an outer shell (1), a connecting block (2) fixedly connected to the rear end of the outer shell (1), and a centrifuge cover (3) rotatably connected to both ends of the connecting block (2), characterized in that: A centrifugal groove (4) is provided at the center of the upper end of the outer shell (1), a centrifugal mechanism (5) is provided at the center of the bottom end of the inner part of the centrifugal groove (4), a plurality of fixed grooves (6) are provided at the surrounding positions of the bottom end of the inner part of the centrifugal groove (4), a lifting mechanism (7) is provided in the fixed groove (6), a display screen (8) is provided at the upper end of the front outer surface of the outer shell (1), a switch button (9) is provided at the lower end of the front outer surface of the outer shell (1), and an adjusting knob (10) is provided on the left side of the switch button (9).

2. A centrifuge for cell experiments according to claim 1, characterized in that: The centrifugal mechanism (5) comprises a motor (51) fixedly connected to the center position of the bottom end of the centrifugal tank (4); a rotating shaft (52) is arranged at the output end of the motor (51); a cross connecting plate (53) is fixedly connected to the upper end of the rotating shaft (52); a placement plate is arranged on the side of the cross connecting plate (53) away from the rotating shaft; a limiting groove is provided at the center position of the mounting surface of the placement plate; the upper end of the cross connecting plate (53) is inserted into the limiting groove (54); the limiting groove (54) has the same size as the cross connecting plate (53); and a plurality of placement holes (56) are provided at the upper end of the placement plate (55).

3. A centrifuge for cell experiments according to claim 2, characterized in that: The lifting mechanism (7) comprises a telescopic rod (71) fixedly connected to the center position inside the fixed groove (6); the output end of the telescopic rod (71) is fixedly connected to the surrounding positions of the lower end of the lifting plate (72); a slot (73) is provided in the middle position of the lifting plate (72); and the size of the slot (73) is the same as that of the motor (51).

4. A centrifuge for cell experiments according to claim 3, characterized in that: A plurality of test tube slots (11) are arranged around the upper end of the lifting plate (72).

5. A centrifuge for cell experiments according to claim 1, characterized in that: The upper surface of the outer shell (1) is provided with a groove (12), and the groove (12) is located on the left and right sides of the upper end of the centrifugal groove (4).

6. A centrifuge for cell experiments according to claim 2, characterized in that: The placement hole (56) is provided with a rubber anti-slip coating inside.

7. A centrifuge for cell experiments according to claim 1, characterized in that: A plurality of suction cups (13) are arranged at the outer bottom end of the outer shell (1).

8. A centrifuge for cell experiments according to claim 2, characterized in that: The outer surface of the placement plate (55) is provided with a transverse anti-slip groove.

Citation Information

Patent Citations

  • Centrifugal machine for cell experiment

    CN217411114U