Reagent bottle cleaning equipment for cell culture
By using hydraulic cylinder, motor and pulley structures in the cell culture reagent bottle cleaning equipment, the uniform rotation of the reagent bottle during cleaning is achieved, the problem of incomplete cleaning of existing equipment is solved, the cleaning effect is improved, and the rotation of the cleaning brush is ensured to complete cleaning of the reagent bottle.
Patent Information
- Application Number
- CN202421028376.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-05-13
- Publication Date
- 2025-02-28
- Estimated Expiration
- 2034-05-13
AI Technical Summary
The existing reagent bottle cleaning equipment for cell culture cannot drive the reagent bottle to rotate during cleaning, resulting in the cleaning solution not being able to evenly cover all surfaces of the reagent bottle, especially the bottom and bottlenecks. The cleaning effect is poor and it is difficult to completely remove dirt and contaminants.
Through the coordination of hydraulic cylinder, fixed box, slider, slider, motor 1, rotating shaft and active pulley, the reagent bottle is driven to rotate during water spraying, so that the cleaning liquid can cover the inner and outer surfaces of the reagent bottle more evenly. At the same time, through the cooperation of the active bevel gear, driven bevel gear, positioning plate, electric push rod and cleaning brush, the cleaning brush is quickly and evenly rotated in the bottle, ensuring thorough cleaning of the reagent bottle.
The reagent bottle is evenly rotated during rinsing with water spray, ensuring that all areas are fully cleaned, improving the cleaning effect, and effectively removing residual contaminants, bacteria and cell residues by rotating the brush, ensuring that the interior of the reagent bottle is thoroughly cleaned.
Smart Images
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Abstract
Description
Technical Field
[0001] The utility model relates to the field of biotechnology, in particular to a reagent bottle cleaning device for cell culture. Background Art
[0002] Cells are the basic structural and functional units of organisms and are the basic components of organisms. In the process of cell culture, in order to maintain the health and growth of cells, appropriate culture media, culture reagents and conditions need to be used. Reagent bottles are containers for storing and mixing different reagents. Commonly used culture media, culture fluids, culture reagents, etc. in cell culture also need to be stored and stirred in reagent bottles. During the use of reagent bottles, residual attachments, contaminants or microorganisms may remain, which have adverse effects on cultured cells, such as cell growth retardation, cell contamination, cell death, etc. Thorough cleaning with reagent bottle cleaning equipment can effectively eliminate these contaminants and keep the culture environment clean.
[0003] When an existing cell culture reagent bottle cleaning device is in use, the cleaning box, base, liquid outlet pipe, collection box and water inlet are used in coordination with each other, so as to achieve the purpose of conveniently collecting waste water by the biological cell culture reagent bottle cleaning device. The cleaning water in the cleaning box is discharged into the collection box through the liquid outlet pipe, which is very convenient.
[0004] However, when using this method, the reagent bottle cannot be driven to rotate during cleaning. The lack of the reagent bottle rotation function will cause the cleaning liquid to be unable to evenly cover all surfaces of the reagent bottle, especially the bottom and bottleneck of the reagent bottle, resulting in poor cleaning effect and difficulty in completely removing dirt and contaminants. The lack of the reagent bottle rotation function will cause some corners or hard-to-reach areas inside the reagent bottle to be unable to be effectively cleaned, easily forming dead corners, accumulating dirt and bacteria, and increasing the risk of cross infection. Utility Model Content
[0005] In order to make up for the above shortcomings, the utility model provides a cell culture reagent bottle cleaning device, aiming to improve the problem that the cell culture reagent bottle cleaning device in the prior art cannot drive the reagent bottle to rotate during cleaning.
[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a reagent bottle cleaning device for cell culture, comprising a cleaning box, a support plate is fixedly connected to the inside of the cleaning box, a through groove is opened inside the support plate, hydraulic cylinders are fixedly connected to the outside of the cleaning box on both sides, multiple output ends of the hydraulic cylinders are fixedly connected to a fixed box, both sides of the bottom of the fixed box are fixedly connected to limiting components, one side of the fixed box is fixedly connected to a motor 1, the output end of the motor 1 is fixedly connected to a rotating shaft, the outside of the rotating shaft is fixedly connected to a driving pulley, the driving pulley is connected to a driven pulley via a belt, the insides of the two driven pulleys are fixedly connected to a rotating rod, the other ends of the rotating shaft and the rotating rod are fixedly connected to a clamping member, and multiple mounting plates are slidably connected to the inside of the through groove.
[0007] Furthermore, the upper part of the cleaning box is fixedly connected to motor 2, the output end of motor 2 is fixedly connected to a transmission shaft, the outside of the transmission shaft is fixedly connected to a driving bevel gear, the lower part of the driving bevel gear is meshingly connected to a driven bevel gear, the inside of the driven bevel gear is fixedly connected to a transmission rod, the bottom of the transmission rod is fixedly connected to a positioning plate, the bottom of the positioning plate is fixedly connected to an electric push rod, and the output end of the electric push rod is fixedly connected to a cleaning brush.
[0008] Furthermore, the limiting assembly includes sliders, the sliders are fixedly connected to both sides of the bottom of the fixing box, the sliders are slidably connected to the outside of the sliding rod, and the sliding rod is fixedly connected to the inside of the supporting plate.
[0009] Furthermore, the upper parts of the two fixing boxes are fixedly connected with a mounting plate, and a limiting groove is provided inside the mounting plate.
[0010] Furthermore, a connecting rod is fixedly connected to one side of the plurality of clamping members that is away from each other, and a limiting block is fixedly connected to the other end of the connecting rod, and the limiting block is slidably connected to the inside of the limiting groove.
[0011] Furthermore, a placement plate is fixedly connected to the rear of the cleaning box, a water pump is fixedly connected to the upper part of the placement plate, an input end of the water pump is fixedly connected to a connecting pipe, and the other end of the connecting pipe is fixedly connected to a water storage tank.
[0012] Furthermore, the output end of the water pump is fixedly connected to a water pipe, the other end of the water pipe is fixedly connected to a drainage pipe, a nozzle is provided at the bottom of the drainage pipe, and the drainage pipe is fixedly connected to both sides of the interior of the cleaning box.
[0013] Furthermore, a water outlet pipe is provided on the left side of the cleaning box, a filter plate is fixedly connected to the inside of the cleaning box, and a box door is rotatably connected to the front of the cleaning box.
[0014] The utility model has the following beneficial effects:
[0015] 1. In the utility model, through the cooperation of multiple structures such as a hydraulic cylinder, a fixed box, a slider, a slide rod, a motor, a rotating shaft and a driving pulley, it is possible to drive the reagent bottle to rotate during water spraying and flushing, so that the cleaning liquid can cover the inner and outer surfaces of the reagent bottle more evenly, ensuring that all areas are fully cleaned, thereby improving the cleaning effect.
[0016] 2. In the utility model, through the cooperation of multiple structures such as the active bevel gear, the driven bevel gear, the positioning plate, the electric push rod and the cleaning brush, the cleaning brush can be made to rotate quickly and evenly in the bottle, effectively removing residual pollutants, bacteria and cell residues, and ensuring thorough cleaning of the inside of the reagent bottle. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 This is a front perspective view of a reagent bottle cleaning device for cell culture proposed by the utility model;
[0018] Figure 2 This is a schematic diagram of the internal structure of a cleaning box of a cell culture reagent bottle cleaning device proposed by the utility model;
[0019] Figure 3 This is a rear perspective view of a cell culture reagent bottle cleaning device proposed by the utility model;
[0020] Figure 4 This is a top perspective view of a cell culture reagent bottle cleaning device proposed by the utility model;
[0021] Figure 5 This is a partial structural schematic diagram of a reagent bottle cleaning device for cell culture proposed by the utility model;
[0022] Figure 6 for Figure 5 Enlarged view of point A in the middle.
[0023] Legend:
[0024] 1. Cleaning box; 2. Box door; 3. Support plate; 4. Hydraulic cylinder; 5. Fixed box; 6. Slider; 7. Slide bar; 8. Motor 1; 9. Rotating shaft; 10. Driving pulley; 11. Belt; 12. Driven pulley; 13. Rotating rod; 14. Clamping piece; 15. Connecting rod; 16. Limit block; 17. Limit groove; 18. Mounting plate; 19. Motor 2; 20. Transmission shaft; 21. Driving bevel gear; 22. Driven bevel gear; 23. Positioning plate; 24. Electric push rod; 25. Cleaning brush; 26. Placement plate; 27. Water tank; 28. Water pump; 29. Connecting pipe; 30. Water pipe; 31. Drain pipe; 32. Sprinkler; 33. Water outlet pipe; 34. Filter plate; 35. Transmission rod. DETAILED DESCRIPTION
[0025] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0026] Reference Figure 2 , Figure 5 and Figure 6 The utility model provides an embodiment of a reagent bottle cleaning device for cell culture, comprising a cleaning box 1, a support plate 3 is fixedly connected to the inside of the cleaning box 1, a through groove is provided inside the support plate 3, hydraulic cylinders 4 are fixedly connected to the outside of the cleaning box 1 on both sides, a plurality of output ends of the hydraulic cylinders 4 are fixedly connected to a fixed box 5, both sides of the bottom of the fixed box 5 are fixedly connected to a limiting assembly, the limiting assembly comprises a slider 6, the slider 6 is fixedly connected to both sides of the bottom of the fixed box 5, the slider 6 is slidably connected to the outside of a slide rod 7, the slide rod 7 is fixedly connected to the inside of the support plate 3, a motor 8 is fixedly connected to one side of the fixed box 5, and the output end of the motor 8 is fixedly connected There is a rotating shaft 9, the outside of the rotating shaft 9 is fixedly connected with a driving pulley 10, the driving pulley 10 is connected to a driven pulley 12 through a belt 11, the insides of the two driven pulleys 12 are fixedly connected with a rotating rod 13, the other ends of the rotating shaft 9 and the rotating rod 13 are fixedly connected with a clamping member 14, a plurality of mounting plates 18 are slidably connected to the inside of the through groove, the upper parts of the two fixed boxes 5 are fixedly connected with the mounting plates 18, the inside of the mounting plates 18 is provided with a limiting groove 17, the side away from the plurality of clamping members 14 is fixedly connected with a connecting rod 15, the other end of the connecting rod 15 is fixedly connected with a limiting block 16, and the limiting block 16 is slidably connected to the inside of the limiting groove 17.
[0027] Start the hydraulic cylinder 4, the output end of the hydraulic cylinder 4 pushes the fixed box 5 to move, and this moving action further drives the slider 6 to slide outside the slide bar 7. Under the action of the slider 6, the two fixed boxes 5 drive the clamping members 14 to approach each other until the two clamping members 14 clamp the reagent bottle tightly. At this time, close the hydraulic cylinder 4 to ensure that the reagent bottle is firmly fixed, start the motor 8, and the output end of the motor 8 drives the shaft 9 to rotate. When the shaft 9 rotates, it drives the driving pulley 10 to rotate. The driving pulley 10 is connected to the driven pulley 12 through the belt 11, so when the driving pulley 10 is connected to the driven pulley 12 through the belt 11, When the pulley 10 rotates, the driven pulley 12 will also rotate accordingly. The rotation of the driven pulley 12 drives the rotating rod 13 to rotate, and the rotating shaft 9 and the rotating rod 13 will drive the clamping member 14 to rotate together. Since the clamping member 14 has tightly clamped the reagent bottle, the reagent bottle will also rotate accordingly. During the rotation of the reagent bottle, the connecting rod 15 will also rotate accordingly. The other end of the connecting rod 15 is connected to the limit block 16, and the limit block 16 slides inside the limit groove 17. The existence of the limit block 16 ensures that the reagent bottle can remain stable during rotation and will not deviate from the predetermined track.
[0028] Reference Figure 2-Figure 4 The upper part of the cleaning box 1 is fixedly connected to a motor 2 19, the output end of the motor 2 19 is fixedly connected to a transmission shaft 20, the outside of the transmission shaft 20 is fixedly connected to a driving bevel gear 21, the lower part of the driving bevel gear 21 is meshedly connected to a driven bevel gear 22, the inside of the driven bevel gear 22 is fixedly connected to a transmission rod 35, the bottom of the transmission rod 35 is fixedly connected to a positioning plate 23, the bottom of the positioning plate 23 is fixedly connected to an electric push rod 24, and the output end of the electric push rod 24 is fixedly connected to a cleaning brush 25.
[0029] Start motor 2 19. When motor 2 19 is started, its output end begins to drive the transmission shaft 20 to rotate. The rotation of the transmission shaft 20 further drives the rotation of the active bevel gear 21. A bevel gear transmission relationship is formed between the active bevel gear 21 and the driven bevel gear 22. When the active bevel gear 21 rotates, the driven bevel gear 22 will also rotate accordingly. The cooperation between them ensures the smooth transmission of power. The rotation of the driven bevel gear 22 further drives the rotation of the transmission rod 35. The transmission rod 35 is a key component connecting the positioning plate 23 and the driven bevel gear 22. It transmits the rotational power to the positioning plate 23. The positioning plate 23 drives the rotation of the electric push rod 24 and the cleaning brush 25 to ensure that they can rotate quickly and evenly inside the reagent bottle. Start the electric push rod 24. The output end of the electric push rod 24 will push the cleaning brush 25 to move downward, so that it extends into the interior of the reagent bottle. The cleaning brush 25 is made of soft and durable material and can easily cope with various complex cleaning tasks.
[0030] Reference Figure 1-Figure 3A placement plate 26 is fixedly connected to the rear of the cleaning box 1, a water pump 28 is fixedly connected to the upper part of the placement plate 26, a connecting pipe 29 is fixedly connected to the input end of the water pump 28, the other end of the connecting pipe 29 is fixedly connected to the water storage tank 27, a water pipe 30 is fixedly connected to the output end of the water pump 28, the other end of the water pipe 30 is fixedly connected to a drain pipe 31, a nozzle 32 is provided at the bottom of the drain pipe 31, the drain pipe 31 is fixedly connected to both sides of the inside of the cleaning box 1, a water outlet pipe 33 is provided on the left part of the cleaning box 1, a filter plate 34 is fixedly connected to the inside of the cleaning box 1, and the front part of the cleaning box 1 is rotatably connected to the box door 2.
[0031] The placement plate 26 provides a stable installation foundation for the water pump 28. The water pump 28 draws water from the inside of the water tank 27 through the connecting pipe 29, transports the water to the drain pipe 31 through the water pipe 30, and finally sprays the water through the nozzle 32. By providing a filter plate 34, impurities in the water can be filtered, and the water is discharged through the outlet pipe 33.
[0032] Working principle: First, place multiple reagent bottles between the two clamping members 14, start the hydraulic cylinder 4, and the output end of the hydraulic cylinder 4 pushes the fixed box 5 to move. The movement of the fixed box 5 drives the slider 6 to slide on the outside of the slide bar 7. Under the action of the slider 6, the two fixed boxes 5 drive the clamping members 14 to get closer until the two clamping members 14 clamp the reagent bottles, close the hydraulic cylinder 4, and then start the motor 8. The output end of the motor 8 drives the rotating shaft 9 to rotate. The rotation of the rotating shaft 9 drives the driving pulley 10 to rotate. The rotation of the driving pulley 10 drives the driven pulley 12 connected by the belt 11 to rotate. The rotation of the driven pulley 12 drives the rotating rod 13 to rotate. When the rotating shaft 9 and the rotating rod 13 rotate, the clamping member 14 is driven to rotate. When the clamping member 14 rotates, the connecting rod 15 is driven to rotate. The connecting rod 15 rotates and drives the limit block 16 to slide inside the limit groove 17. Under the action of the limit block 16, the clamping member 14 drives the reagent bottle to rotate, thereby realizing that the reagent bottle can be driven to rotate during water spraying. Rotation allows the cleaning liquid to more evenly cover the inner and outer surfaces of the reagent bottle, ensuring that all areas are fully cleaned and improving the cleaning effect. Start the motor 2 19. The output end of the motor 2 19 drives the transmission shaft 20 to rotate. The rotation of the transmission shaft 20 drives the active bevel gear 21 to rotate. The rotation of the active bevel gear 21 drives the driven bevel gear 22 to rotate. The rotation of the driven bevel gear 22 drives the transmission rod 35 to rotate. The rotation of the transmission rod 35 drives the positioning plate 23 to rotate. The rotation of the positioning plate 23 drives the electric push rod 24 and the cleaning brush 25 to rotate. Start the electric push rod 24. The output end of the electric push rod 24 pushes the cleaning brush 25 to move downward. When the reagent bottle is rinsed, the bottle mouth of the reagent bottle is facing upward, so that the cleaning brush 25 is extended into the interior of the reagent bottle, and the cleaning brush 25 is rotated to clean the interior of the reagent bottle, thereby achieving that the cleaning brush 25 can rotate quickly and evenly in the bottle, effectively removing residual pollutants, bacteria and cell residues, and ensuring thorough cleaning of the interior of the reagent bottle.
[0033] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.
Claims
1. A cell culture reagent bottle cleaning device, comprising a cleaning box (1), characterized in that: The interior of the cleaning box (1) is fixedly connected to a support plate (3), the interior of the support plate (3) is provided with a through groove, the exterior of the cleaning box (1) is fixedly connected to hydraulic cylinders (4) on both sides, the output ends of the plurality of hydraulic cylinders (4) are fixedly connected to a fixed box (5), the bottom sides of the fixed box (5) are fixedly connected to a limiting assembly, one side of the fixed box (5) is fixedly connected to a motor 1 (8), the output end of the motor 1 (8) is fixedly connected to a rotating shaft (9), the exterior of the rotating shaft (9) is fixedly connected to A driving pulley (10) is provided, the driving pulley (10) is connected to a driven pulley (12) via a belt (11), a rotating rod (13) is fixedly connected inside the two driven pulleys (12), the other ends of the rotating shaft (9) and the rotating rod (13) are fixedly connected to a clamping member (14), the upper parts of the two fixed boxes (5) are fixedly connected to a mounting plate (18), a limiting groove (17) is provided inside the mounting plate (18), and a plurality of the mounting plates (18) are slidably connected inside the through groove.
2. The cell culture reagent bottle cleaning device according to claim 1, characterized in that: The upper part of the cleaning box (1) is fixedly connected to a second motor (19); the output end of the second motor (19) is fixedly connected to a transmission shaft (20); the outside of the transmission shaft (20) is fixedly connected to a driving bevel gear (21); the lower part of the driving bevel gear (21) is meshingly connected to a driven bevel gear (22); the inside of the driven bevel gear (22) is fixedly connected to a transmission rod (35); the bottom of the transmission rod (35) is fixedly connected to a positioning plate (23); the bottom of the positioning plate (23) is fixedly connected to an electric push rod (24); the output end of the electric push rod (24) is fixedly connected to a cleaning brush (25).
3. The cell culture reagent bottle cleaning device according to claim 1, characterized in that: The limiting assembly comprises a slider (6), wherein the slider (6) is fixedly connected to two sides of the bottom of the fixing box (5), the slider (6) is slidably connected to the outside of the sliding rod (7), and the sliding rod (7) is fixedly connected to the inside of the supporting plate (3).
4. The cell culture reagent bottle cleaning device according to claim 1, characterized in that: The sides of the plurality of clamping members (14) that are away from each other are fixedly connected to a connecting rod (15), the other end of the connecting rod (15) is fixedly connected to a limiting block (16), and the limiting block (16) is slidably connected inside a limiting groove (17).
5. The cell culture reagent bottle cleaning device according to claim 1, characterized in that: The rear of the cleaning box (1) is fixedly connected to a placement plate (26), the upper part of the placement plate (26) is fixedly connected to a water pump (28), the input end of the water pump (28) is fixedly connected to a connecting pipe (29), and the other end of the connecting pipe (29) is fixedly connected to a water storage tank (27).
6. The cell culture reagent bottle cleaning device according to claim 5, characterized in that: The output end of the water pump (28) is fixedly connected to a water pipe (30), the other end of the water pipe (30) is fixedly connected to a drainage pipe (31), a nozzle (32) is provided at the bottom of the drainage pipe (31), and the drainage pipe (31) is fixedly connected to both sides of the interior of the cleaning box (1).
7. The cell culture reagent bottle cleaning device according to claim 1, characterized in that: The left part of the cleaning box (1) is provided with a water outlet pipe (33), the interior of the cleaning box (1) is fixedly connected with a filter plate (34), and the front part of the cleaning box (1) is rotatably connected with a box door (2).