Device for separating and purifying metal nuclide

Abstract

The utility model provides a device for separating and purifying metal nuclides. The device comprises a base, a top cover and an outer cylinder positioned between the base and the top cover, wherein the top cover consists of an upper sleeve and a cooling container; the upper sleeve is of a hollow cylinder structure, the bottom of the upper sleeve is open, the top of the upper sleeve and the bottom of the cooling container are fixedly sealed, and the bottom of the upper sleeve is slightly higher than the upper surface of the base. The device disclosed by the utility model is simple in structure and convenient to operate, and can meet the requirement of sublimation separation of radionuclides; the device is small in size and can be put into a protection box, the whole purification process is operated in the protection box, and the radiation risk is reduced; metal steam obtained in the sublimation process is mainly condensed in the upper sleeve and can be conveniently dissolved with acid to be recycled and reused.

Description

Technical Field

[0001] The utility model relates to the field of metal nuclide separation and purification devices, in particular to a device used for separation and purification of radioactive metal nuclides. Background Art

[0002] Radioactive metal nuclides are usually produced by a particle accelerator that injects a particle beam onto a solid target material to produce the corresponding radioactive nuclides through nuclear reactions, such as bombarding a Zn target to produce 67 Cu or 68 Ga, etc., the solid target is dissolved with acid and then chemically separated by an ion exchange column to finally obtain the desired radioactive metal nuclides.

[0003] First, the traditional methods for separating radioactive metal nuclides generally have problems such as long process flow, difficult product elution, high consumption of chemical reagents, and secondary pollution caused by waste liquid treatment. In addition, the Zn targets used in accelerator production of metal nuclides are mostly enriched. 68 Zn, 68 The abundance of Zn is only 18.84%, so the enriched Zn target is very expensive. Therefore, in order to improve the recovery rate of the target metal, researchers tried to use vacuum sublimation to physically separate the target and the generated nuclides. This separation method can greatly improve the purification efficiency of nuclides and the recovery rate of target metal, and reduce the radiation damage to technicians during operation. However, the existing sublimation device has a relatively complex structure and has certain limitations in temperature control, post-separation processing and protection. Utility Model Content

[0004] In order to solve the above technical problems, the utility model provides a device for separation and purification of metal nuclides.

[0005] In order to achieve the above purpose, the utility model provides the following technical solutions:

[0006] A device for separation and purification of metal nuclides comprises a base, a top cover and an outer cylinder located between the base and the top cover; wherein the base comprises a pedestal, a heater and a target cavity; the top cover consists of an upper sleeve and a cooling container; the upper sleeve is a hollow cylindrical structure with an open bottom, the top of the upper sleeve is fixedly sealed with the bottom of the cooling container, and the bottom of the upper sleeve is slightly higher than the upper surface of the base.

[0007] Specifically, the material of the base is a heat-insulating material, such as graphite, RCC, etc.; the material of the top cover is a high-temperature-resistant and acid-resistant material, such as quartz, oxide ceramics, etc.

[0008] Furthermore, the top of the target cavity is open and located inside the upper sleeve; the upper sleeve is located inside the outer sleeve.

[0009] Specifically, the target piece cavity may be a crucible.

[0010] Furthermore, both ends of the outer tube are open; positioning grooves are provided on the upper surface of the base and the lower surface of the cooling container; and sealing rings are arranged in the positioning grooves for installation, fixation and sealing of the outer tube.

[0011] Specifically, a clamping groove is provided in the sealing ring, and the cross section of the clamping groove is U-shaped, and the size is matched with the two ends of the outer cylinder and the inner wall of the positioning groove.

[0012] Furthermore, the bottom and top ends of the outer tube may have protruding portions for tightly fitting with the inside of the groove of the sealing ring.

[0013] Specifically, the material of the outer cylinder is a high temperature resistant material, such as quartz, oxide ceramics, etc., and the material of the sealing ring is a high temperature resistant elastic material.

[0014] Furthermore, a vacuum valve and a vent valve are provided on the side of the outer cylinder.

[0015] Furthermore, the vacuum valve is connected to a vacuum pump, and the ventilation valve is connected to an inert gas.

[0016] Specifically, the inert gas is argon.

[0017] Furthermore, the heater is built into the base and is located directly below the target cavity; the heater is externally connected to a temperature controller.

[0018] Specifically, the heating temperature of the heater can be as high as 600-900°C.

[0019] Furthermore, the cooling container is provided with a liquid inlet and a liquid outlet, and the container is filled with cooling liquid.

[0020] The beneficial effects of the utility model are: 1. The device of the utility model has a simple structure and is easy to operate, and can meet the needs of sublimation separation of radioactive nuclides; 2. The device is small in size and can be placed in a protective box. The entire separation and purification process is carried out in the protective box, which reduces the radiation risk; 3. The metal vapor obtained in the sublimation process is mainly condensed inside the upper sleeve, which is convenient for dissolution with acid for recovery and reuse. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a cross-sectional view of the device described in the utility model;

[0022] Wherein, the reference numerals represent:

[0023] 1-base; 2-heater; 3-target cavity; 4-outer cylinder; 51-upper sleeve; 52-cooling container; 6-positioning groove; 7-sealing ring; 8-vacuum valve; 9-vent valve; 21-temperature controller; 71-card slot. DETAILED DESCRIPTION

[0024] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0025] like Figure 1 As shown, the device includes a base, a top cover and an outer cylinder 4 located between the base and the top cover, wherein the base includes a susceptor 1, a heater 2 and a target cavity 3.

[0026] The top cover is composed of an upper sleeve 51 and a cooling container 52; the upper sleeve 51 is a hollow cylindrical structure with an open bottom, and the top is fixedly sealed with the bottom of the cooling container 52; the bottom of the upper sleeve 51 is slightly higher than the upper surface of the base 1.

[0027] The top of the target cavity 3 is open and located inside the upper sleeve 51 , and the upper sleeve 51 is located inside the outer cylinder 4 .

[0028] Both ends of the outer tube 4 are open; positioning grooves 6 are provided on the upper surface of the base 1 and the lower surface of the cooling container 52; and sealing rings 7 are arranged in the positioning grooves 6 for installation, fixing and sealing of the outer tube 4.

[0029] A clamping groove 71 is provided in the sealing ring 7 . The cross section of the clamping groove 71 is U-shaped, and the size thereof is matched with the two ends of the outer cylinder 4 and the inner wall of the positioning groove 6 .

[0030] A vacuum valve 8 and a vent valve 9 are provided on the side of the outer tube 4; the vacuum valve 8 is connected to a vacuum pump, and the vent valve 9 is connected to argon gas.

[0031] The heater 2 is built in the base 1 and is located directly below the target cavity 3 ; the heater 2 is externally connected to a temperature controller 21 .

[0032] The cooling container 52 is provided with a liquid inlet pipe and a liquid outlet pipe, and the container is filled with cooling liquid.

[0033] In the separation of nuclides using the above device 67 Cu, the operation process is as follows:

[0034] (1) Insert the bottom end of the outer tube 4 into the slot 71 of the sealing ring 7 on the base 1, use tweezers to place the Zn target after accelerator shooting into the target cavity 3, and engage the sealing ring 7 at the bottom of the cooling container 52 with the top of the outer tube 4 to complete the installation of the device.

[0035] (2) After installation, open the liquid inlet and outlet pipes on the cooling container 52 to allow the cooling circulating liquid to flow in. Open the vacuum valve 8 and start the vacuum pump. Wait until the pressure in the device reaches 1.5×10 -1Pa, start the heater 2 to heat the target cavity 3, and heat the Zn target inside it to 150°C. Then close the vacuum pump and vacuum valve 8, open the vent valve 9 to let argon gas in. After a period of time, close the vent valve 9, open the vacuum valve 8 and the vacuum pump again, and make the pressure in the device reach 1.5×10 -1 Pa, and repeat this process three times. Then, the vacuum pump and vacuum valve 8 are closed, and the heater 2 is controlled to heat the Zn target in the target cavity 3 to 700°C. The temperature is kept constant, and the metal Zn sublimates for 80 minutes. The Zn vapor rises to the bottom of the cooling container 52 and is condensed, and is concentrated inside the upper sleeve 51.

[0036] (3) After the sublimation and desublimation are completed, turn off the heater 2 and maintain the circulating cooling. After the device is cooled to a suitable temperature, turn off the cooling circulating liquid, remove the top cover and turn it upside down.

[0037] (4) Add 2 mL of 6 M hydrochloric acid into the target cavity 3, cover the top of the target cavity 3 with a lid connected to an acid removal column and a nitrogen blower, and then turn on the heater 2 to heat to 90°C to dissolve the substances in the target cavity 3. After the acid is evaporated, turn off the heater 2, wait until the target cavity 3 returns to room temperature, add 5 mL of 0.001 M hydrochloric acid solution to dissolve, transfer the solution to the Cu resin column, and elute with 2 mL of 6 M hydrochloric acid to obtain 67 Cu solution, used for subsequent radiopharmaceutical labeling.

[0038] (5) Add an appropriate amount of 10 M sulfuric acid solution to the inverted upper sleeve 51 to obtain 68 The recovered Zn solution can be used for the subsequent preparation of Zn target.

[0039] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A device for separation and purification of metal nuclides, characterized in that: It includes a base, a top cover and an outer cylinder located between the base and the top cover; wherein the base includes a base, a heater and a target cavity; the top cover is composed of an upper sleeve and a cooling container; the upper sleeve is a hollow cylindrical structure with an open bottom, the top of the upper sleeve is fixedly sealed to the bottom of the cooling container, and the bottom of the upper sleeve is slightly higher than the upper surface of the base.

2. The device according to claim 1, characterized in that The top of the target cavity is open and located inside the upper sleeve; the upper sleeve is located inside the outer sleeve.

3. The device according to claim 1, characterized in that Both ends of the outer cylinder are open; positioning grooves are provided on the upper surface of the base and the lower surface of the cooling container; sealing rings are arranged in the positioning grooves for installation, fixation and sealing of the outer cylinder.

4. The device according to claim 3, characterized in that A clamping groove is arranged in the sealing ring, and the cross section of the clamping groove is U-shaped.

5. The device according to claim 3, characterized in that A vacuum valve and a vent valve are arranged on the side of the outer cylinder.

6. The device according to claim 1, characterized in that The heater is built in the base and is located directly below the target cavity; the heater is externally connected to a temperature controller.

7. The device according to claim 1, characterized in that The cooling container is provided with a liquid inlet and a liquid outlet, and the container is filled with cooling liquid.

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