Portable stem cell extraction device

Abstract

The utility model relates to the technical field of stem cell extraction, in particular to a portable stem cell extraction device which comprises a bearing base, a mounting bracket and a collecting cylinder, the installation support is connected with the upper end face of the bearing base. The projection of the installation support is of a rectangular hollow structure. The mounting bracket is provided with a reset assembly for adjusting the collection barrel to descend to extract the stem cells and resetting the stem cells; an adjusting assembly used for transversely adjusting the position of the reset assembly is arranged on the installation support. According to the stem cell extraction device, the adjusting assembly used for transversely adjusting the position of the reset assembly is installed on the installation support, and the installation bases and the idler wheels are evenly installed at the bottom end of the bearing base, so that the position of the device can be moved according to the position where stem cells need to be extracted; after the position is determined, stem cells are extracted from the object to be extracted by changing the position of the tube body through the adjusting assembly according to the specific position of the stem cell object to be extracted, and the stem cell extractor is suitable for various environments and convenient to carry.

Description

Technical Field

[0001] The utility model relates to the technical field of stem cell extraction, in particular to a portable stem cell extraction device. Background Art

[0002] At present, the main methods used in the laboratory to extract and separate bone marrow mesenchymal stem cells include density gradient centrifugation, wall-adherence screening method (whole bone marrow wall-adherence method), cell surface molecular marker sorting method and cell screening method, among which the most commonly used is the combined use of density gradient centrifugation and wall-adherence screening method. In the process of density gradient centrifugation, the bone marrow fluid is centrifuged in the test tube and the liquid column in the test tube is divided into 4 layers. The first layer is the culture fluid layer, the second layer is the mononuclear cell layer (containing the bone marrow mesenchymal stem cells we need), the third layer is the lymphocyte separation fluid layer, and the fourth layer is the red blood cells and multinuclear cell layer.

[0003] The utility model with authorization announcement number CN217868799U discloses a device for extracting stem cells, including a base plate, a fixed frame fixed at one end of the top of the base plate, and a threaded rod rotatably connected in the fixed frame, the threaded rod is screwed with a fixed frame, an adjustment mechanism is provided on the fixed frame, and the adjustment mechanism clamps the extraction mechanism, the adjustment mechanism includes an I-shaped block, a pipe clamp fixed to the outer wall of one side of the I-shaped block, a movable rod inserted in the I-shaped block and a limit block fixed to the top of the movable rod, the extraction mechanism includes an extraction barrel, a needle tube inserted and fixed to the bottom end of the extraction barrel, a barrel cover inserted at the top end of the extraction barrel, a thin screw screwed to the top of the barrel cover and a piston rotatably connected to the bottom end of the thin screw.

[0004] However, the above technical solution has the following defects: when the device adjusts the position of the extraction mechanism on the fixed frame, it is necessary to lift the limit block and limit the limit block through the cooperation of the teeth and the tooth grooves to adjust the position of the extraction mechanism. The operation is cumbersome and reduces the extraction efficiency. Utility Model Content

[0005] The utility model aims to provide a portable stem cell extraction device in view of the problems existing in the background technology.

[0006] The technical solution of the utility model: a portable stem cell extraction device, including a bearing base, a mounting bracket and a collection tube;

[0007] The mounting bracket is connected to the upper end surface of the bearing base, and the projection of the mounting bracket is a rectangular hollow structure;

[0008] The mounting bracket is provided with a reset component for adjusting the collection tube to descend to extract stem cells and reset;

[0009] An adjusting component for laterally adjusting the position of the reset component is arranged on the mounting bracket.

[0010] Preferably, the reset component includes a mounting block, a threaded rod, a slider and a reset spring;

[0011] The mounting block is slidably connected to the mounting bracket, and a T-shaped chute is formed inside the mounting block;

[0012] The projection of the slider is a T-shaped structure and the slider is located in the T-shaped chute and is slidably connected to the mounting block;

[0013] One side of the slider away from the mounting block is connected to the outer peripheral surface of the collection cylinder, the slider is connected to the reset spring, and the other end of the reset spring is connected to the inner bottom end of the mounting block;

[0014] A threaded hole is formed in the upper end surface of the mounting block, a threaded rod is threadedly connected in the threaded hole, and the lower end of the threaded rod abuts against the upper end surface of the slider.

[0015] Preferably, the adjusting component includes a first fixing plate, a second fixing plate, a handle, a lead screw, a guide rod and a connecting plate;

[0016] The first fixing plate and the second fixing plate are symmetrically installed on both sides of the end surface of the mounting bracket away from the mounting block, and one side of the mounting block away from the collection cylinder is connected to the connecting plate;

[0017] The first fixing plate, the second fixing plate and the connecting plate are coaxially distributed. The lead screw passes through and is threadedly connected to the connecting plate. The lead screw is respectively rotatably connected to the first fixing plate and the second fixing plate, and one end of the lead screw passes through the first fixing plate and is connected to the handle;

[0018] The guide rod passes through and is slidably threadedly connected to the connecting plate, and both ends of the guide rod are respectively rotatably connected to the first fixing plate and the second fixing plate.

[0019] Preferably, a through hole is formed in the connecting plate, a lead screw nut is arranged in the through hole, the outer peripheral surface of the lead screw nut is connected to the inner peripheral surface of the through hole of the connecting plate, and the lead screw passes through the lead screw nut and is threadedly connected to the lead screw nut.

[0020] Preferably, it further includes a cylinder cover;

[0021] Internal threads are provided on the inner side of the cylinder cover, external threads are provided at the lower end of the collection cylinder, and the cylinder cover and the collection cylinder are threadedly connected;

[0022] A pipe body is connected to the center of the end surface of the cylinder cover away from the collection cylinder. The pipe body is a hollow circular pipe and the pipe body penetrates through the lower end surface of the cylinder cover.

[0023] Preferably, mounting seats are provided at the four corners of the bottom end of the bearing base. The projection of the mounting seat is U-shaped. The fixed end of the mounting seat is connected to the lower end surface of the bearing base, and a roller is rotatably arranged inside each mounting seat.

[0024] Compared with the prior art, the above technical solution of the utility model has the following beneficial technical effects: by installing an adjustment component for laterally adjusting the position of the reset component on the mounting bracket, and evenly installing a mounting seat and a roller at the bottom end of the bearing base, the position of the device can be moved according to the position where stem cells need to be extracted. After the position is determined, the position of the tube body is changed by the adjustment component according to the specific position of the object to be extracted with stem cells to extract stem cells from the extraction object. The utility model is suitable for a variety of environments and is easy to carry.

[0025] By installing a reset component for resetting the collection tube on the adjustment component and detachably installing a tube cover on the reset component, the size of the tube body on the tube cover can be changed according to the needs of the extracted object. At the same time, the position of the collection tube is limited by the threaded rod during the extraction process to maintain stable extraction of stem cells. After the extraction is completed, the threaded rod is rotated to loosen the collection tube and the collection tube is reset by the reset spring, thereby reducing manpower output. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 This is a schematic structural diagram of a portable stem cell extraction device proposed by the utility model.

[0027] Figure 2 This is a front view of a portable stem cell extraction device proposed by the utility model.

[0028] Figure 3 for Figure 2 A local enlarged schematic diagram of point A in the middle.

[0029] Figure numerals: 1. load-bearing base; 2. mounting bracket; 3. first fixing plate; 4. second fixing plate; 5. handle; 6. screw rod; 7. guide rod; 8. mounting block; 9. connecting plate; 10. threaded rod; 11. collecting cylinder; 12. slider; 13. cylinder cover; 14. reset spring. DETAILED DESCRIPTION

[0030] Embodiment 1

[0031] like Figure 1-3 As shown, a portable stem cell extraction device proposed by the present invention comprises a bearing base 1, a mounting bracket 2, a collection tube 11 and a tube cover 13;

[0032] The mounting bracket 2 is connected to the upper end surface of the bearing base 1, and the projection of the mounting bracket 2 is a rectangular hollow structure;

[0033] The mounting bracket 2 is provided with a reset component for adjusting the collection tube 11 to descend to extract stem cells and reset;

[0034] The mounting bracket 2 is provided with an adjustment component for laterally adjusting the position of the reset component.

[0035] The adjusting assembly includes a first fixing plate 3, a second fixing plate 4, a handle 5, a lead screw 6, a guide rod 7 and a connecting plate 9;

[0036] The first fixing plate 3 and the second fixing plate 4 are symmetrically installed on both sides of the side end face of the mounting bracket 2 away from the mounting block 8, and a connecting plate 9 is connected to the side of the mounting block 8 away from the collecting cylinder 11;

[0037] The first fixing plate 3, the second fixing plate 4 and the connecting plate 9 are coaxially distributed. The lead screw 6 passes through and is threadedly connected to the connecting plate 9. The lead screw 6 is respectively rotatably connected to the first fixing plate 3 and the second fixing plate 4, and one end of the lead screw 6 passes through the first fixing plate 3 and is connected to the handle 5;

[0038] The guide rod 7 passes through and is slidably threadedly connected to the connecting plate 9, and both ends of the guide rod 7 are respectively rotatably connected to the first fixing plate 3 and the second fixing plate 4.

[0039] A through hole is provided on the connecting plate 9, and a lead screw nut is arranged in the through hole. The outer peripheral surface of the lead screw nut is connected to the inner peripheral surface of the through hole of the connecting plate 9. The lead screw 6 passes through the lead screw nut and is threadedly connected to the lead screw nut, which is convenient for changing the position of the tube body through the adjusting assembly according to the specific position of the object to be extracted with stem cells after the position is determined, so as to extract stem cells from the object to be extracted, and it is applicable to various environments.

[0040] Internal threads are provided on the inner side of the cylinder cover 13, external threads are provided at the lower end of the collecting cylinder 11, and the cylinder cover 13 and the collecting cylinder 11 are threadedly connected;

[0041] A tube body is connected to the center of the end face of the cylinder cover 13 away from the collecting cylinder 11. The tube body is a hollow circular tube, and the tube body penetrates through the lower end face of the cylinder cover 13.

[0042] Mounting seats are arranged at the four corners of the bottom end of the bearing base 1. The projection of the mounting seat is U-shaped. The fixed end of the mounting seat is connected to the lower end face of the bearing base 1. A roller is rotatably arranged inside each mounting seat, which is convenient for changing the extraction position at any time according to needs and is convenient for carrying.

[0043] Embodiment 2

[0044] As Figure 1-3 shown, a portable stem cell extraction device proposed by the present utility model further specifically discloses the specific structure of the reset assembly compared with Embodiment 1.

[0045] In this embodiment, the reset assembly includes a mounting block 8, a threaded rod 10, a slider 12 and a reset spring 14;

[0046] The mounting block 8 is slidably connected to the mounting bracket 2, and a T-shaped chute is provided inside the mounting block 8;

[0047] The projection of the slider 12 is a T-shaped structure and the slider 12 is located in the T-shaped slide groove and is slidably connected to the mounting block 8;

[0048] The side of the slider 12 away from the mounting block 8 is connected to the outer peripheral surface of the collecting tube 11, and the slider 12 is connected to the return spring 14, and the other end of the return spring 14 is connected to the inner bottom end of the mounting block 8;

[0049] A threaded hole is provided on the upper end surface of the mounting block 8, and a threaded rod 10 is connected to the thread in the threaded hole. The lower end of the threaded rod 10 abuts against the upper end surface of the slider 12, so that the threaded rod can be rotated to loosen the collection barrel after the extraction is completed and the collection barrel can be reset by a spring, thereby reducing manpower output.

[0050] In summary, in the present invention, the device is first moved to a designated location by manually pushing the rotating roller, and at the same time, the handle 5 is rotated according to the location of the extracted object. When the handle 5 rotates, the screw rod 6 is driven to rotate between the first fixed plate 3 and the second fixed plate 4. When the screw rod 6 rotates, the connecting plate 9 is laterally displaced on the guide rod 7 through the cooperation of the ball nut and the screw rod 6 and the limit guide of the guide rod 7, thereby driving the reset assembly to move laterally. After the displacement is to a suitable position, the handle 5 is stopped from rotating.

[0051] At this time, the threaded rod 10 is rotated forward, and the threaded rod 10 slowly descends on the mounting block 8. The lower end of the threaded rod 10 abuts against the slider 12 and drives the slider 12 to descend. At the same time, the slider 12 compresses the return spring 14 to a compressed state. The slider 12 drives the collection barrel 11 to descend and drives the barrel cover 13 and the tube body on the barrel cover 13 to descend to the designated extraction position, squeezing the outer wall of the collection barrel 11 to form a negative pressure in the collection barrel 11, and aligning the lower end of the tube body with the extraction object, loosening the outer wall of the collection barrel 11, and extracting the object;

[0052] After the extraction is completed, the threaded rod 10 is rotated in the reverse direction, and the collecting tube 11 is gradually reset under the elastic potential energy of the reset spring 14, completing the whole process of extracting stem cells.

[0053] The implementation modes of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited thereto, and various changes can be made within the knowledge scope of technicians in the relevant technical field without departing from the purpose of the present invention.

Claims

1. A portable stem cell extraction device, characterized in that: It includes a bearing base (1), a mounting bracket (2) and a collection cylinder (11); The mounting bracket (2) is connected to the upper end surface of the bearing base (1), and the projection of the mounting bracket (2) is a rectangular hollow structure; A reset assembly for adjusting the downward movement of the collection cylinder (11) to extract stem cells and reset is provided on the mounting bracket (2); An adjusting assembly for horizontally adjusting the position of the reset assembly is provided on the mounting bracket (2).

2. A portable stem cell extraction device according to claim 1, characterized in that: The reset assembly includes a mounting block (8), a threaded rod (10), a slider (12) and a reset spring (14); The mounting block (8) is slidably connected to the mounting bracket (2), and a T-shaped chute is formed inside the mounting block (8); The projection of the slider (12) is a T-shaped structure and the slider (12) is located in the T-shaped chute and is slidably connected to the mounting block (8); One side of the slider (12) away from the mounting block (8) is connected to the outer peripheral surface of the collection cylinder (11), the slider (12) is connected to the reset spring (14), and the other end of the reset spring (14) is connected to the inner bottom end of the mounting block (8); A threaded hole is formed in the upper end surface of the mounting block (8), and the threaded rod (10) is threadedly connected to the threaded hole, and the lower end of the threaded rod (10) abuts against the upper end surface of the slider (12).

3. A portable stem cell extraction device according to claim 2, characterized in that: The adjusting assembly includes a first fixing plate (3), a second fixing plate (4), a handle (5), a lead screw (6), a guide rod (7) and a connecting plate (9); The first fixing plate (3) and the second fixing plate (4) are symmetrically installed on both sides of the end surface of the mounting bracket (2) away from the mounting block (8), and one side of the mounting block (8) away from the collection cylinder (11) is connected to the connecting plate (9); The first fixing plate (3), the second fixing plate (4) and the connecting plate (9) are coaxially distributed, the lead screw (6) passes through and is threadedly connected to the connecting plate (9), the lead screw (6) is respectively rotatably connected to the first fixing plate (3) and the second fixing plate (4), and one end of the lead screw (6) passes through the first fixing plate (3) and is connected to the handle (5); The guide rod (7) passes through and is slidably threadedly connected to the connecting plate (9), and both ends of the guide rod (7) are respectively rotatably connected to the first fixing plate (3) and the second fixing plate (4).

4. A portable stem cell extraction device according to claim 3, characterized in that: A through hole is formed in the connecting plate (9), a lead screw nut is arranged in the through hole, the outer peripheral surface of the lead screw nut is connected to the inner peripheral surface of the through hole of the connecting plate (9), and the lead screw (6) passes through the lead screw nut and is threadedly connected to the lead screw nut.

5. A portable stem cell extraction device according to claim 2, characterized in that: It further includes a cylinder cover (13); Internal threads are provided on the inner side of the cylinder cover (13), external threads are provided at the lower end of the collection cylinder (11), and the cylinder cover (13) is threadedly connected to the collection cylinder (11); A pipe body is connected to the center of the end surface of the cylinder cover (13) away from the collection cylinder (11), the pipe body is a hollow circular pipe, and the pipe body penetrates through the lower end surface of the cylinder cover (13).

6. A portable stem cell extraction device according to claim 1, characterized in that: Mounting seats are arranged at the four corners of the bottom end of the bearing base (1), the projection of the mounting seat is a U-shaped, the fixed end of the mounting seat is connected to the lower end surface of the bearing base (1), and a roller is rotatably arranged inside each mounting seat.

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