Full-automatic liquid sample analyzer
By designing a fully automatic liquid sample analyzer, the problem of inaccurate test strip jams in high-speed equipment and inaccurate detection results of low-speed equipment is solved, and efficient and accurate liquid sample analysis is achieved, which is suitable for small and medium-sized hospitals.
Patent Information
- Application Number
- CN202420597695.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-26
- Publication Date
- 2025-03-18
- Estimated Expiration
- 2034-03-26
AI Technical Summary
现有高速液样分析设备容易出现试纸条卡纸的问题,而低速设备则检测结果不准确,且检测过程繁琐。
A fully automatic liquid sample analyzer is designed, including a sample feeding mechanism, a rotating sample disk mechanism and a sampling mechanism. The orderly separation and detection of test strips are achieved through automated control, avoiding the paper jam of test strips and simplifying the detection process.
The effect of no paper jamming in the test strips in the high-speed liquid sample analysis equipment is achieved, and the detection accuracy and efficiency of low-speed equipment is improved, and it is suitable for liquid sample analysis in small and medium-sized hospitals.
Smart Images

Figure CN222636174U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of medical equipment, in particular to a full-automatic liquid sample analyzer. Background Art
[0002] The analysis of liquid samples can analyze the content of components in the liquid to obtain the liquid properties. It is widely used in scientific experiments, chemical industry, medical treatment and other fields. Common liquid sample analysis instruments and equipment include electrolyte meters, blood cell meters, urine analyzers, etc.
[0003] Taking urine analyzer as an example, urine analysis is one of the most commonly used medical examination items at present, and plays an important role in the diagnosis and treatment of various systemic diseases. Urine dry chemical examination is an important part of urine analysis. Its main principle is to use the specific components in urine to react with the corresponding substances to produce specific color reaction, and the urine analyzer identifies the color of the urine test strip after the reaction to output the test results of various indicators of the urine sample.
[0004] Traditional urine analyzers are mainly composed of sampling components, sample delivery components, sample tray components and optical detection components. Currently, there are two types of urine analyzers commonly found on the market: high-speed and low-speed. High-speed instruments have a high degree of automation, fast detection speed and high efficiency, and are suitable for large hospitals with large detection volumes. During the analysis process, the rotation of the roller can be used to separate the irregular test strips inside the paper bin one by one, and then sent to the next station through the test strip slide and flip slide. However, long-term operation can easily cause multiple test strips to get stuck in the test strip slot, causing the mechanism to get stuck. Although low-speed instruments are small in size and low in cost, they require manual soaking of test strips, test results and removal of test strips. The process is relatively cumbersome and the detection speed is low. They are suitable for some small clinics. Since the effect of manual soaking of the test strips is different each time, the accuracy of the test results will also be affected to a certain extent. Utility Model Content
[0005] The utility model provides a full-automatic liquid sample analyzer, which is used to solve the defects in the prior art that high-speed liquid sample analysis equipment is prone to test paper jams and low-speed liquid sample analysis equipment has inaccurate test results.
[0006] The utility model provides a fully automatic liquid sample analyzer, comprising:
[0007] The sample delivery mechanism comprises a support platform and a test paper separator movably arranged on the support platform, wherein the test paper separator can be moved along the length direction of the support platform, and the test paper separator is provided with a plurality of separation grooves along the width direction of the support platform, and the test paper strips are placed on the support platform and located in the separation grooves;
[0008] A rotating sample tray mechanism is located on the side of the support platform in the length direction, and a plurality of sample tubes are placed on the rotating sample tray mechanism along the rotation direction;
[0009] The sampling mechanism comprises a sampling base plate, a horizontal sampling assembly and a vertical sampling assembly, wherein the sampling base plate is vertically arranged above the sample feeding mechanism and the rotating sample disk mechanism along the width direction of the supporting platform, the horizontal sampling assembly is horizontally arranged on the sampling base plate, and the vertical sampling assembly is arranged on the horizontal sampling assembly, so that the horizontal position of the sampling is adjusted by the horizontal sampling assembly, and the vertical position of the sampling is adjusted by the vertical sampling assembly;
[0010] The control device is suitable for automatically controlling the sample delivery mechanism, the rotating sample disk mechanism and the sampling mechanism.
[0011] According to a fully automatic liquid sample analyzer provided by the utility model, the sample delivery mechanism also includes:
[0012] Sample delivery base plate, the support platform is installed on the sample delivery base plate through the support profile;
[0013] A sample delivery movement control component is installed on the sample delivery bottom plate;
[0014] A sample delivery connection component, connecting the test paper separator plate and the sample delivery movement control component;
[0015] The sample delivery sensor is fixed on the sample delivery bottom plate and is used to detect the position of the test paper separator plate.
[0016] According to a fully automatic liquid sample analyzer provided by the utility model, the sample delivery movement control component includes:
[0017] The sample feeding motor and the sample feeding driven wheel shaft are fixed on the sample feeding bottom plate, and the connecting line between the sample feeding motor and the sample feeding driven wheel shaft is kept parallel to the length direction of the support platform;
[0018] A sample feeding pulley and a sample feeding driven wheel, wherein the sample feeding pulley is fixed on the output shaft of the sample feeding motor, and the sample feeding driven wheel is fixed on the sample feeding driven wheel shaft;
[0019] A sample-feeding synchronous belt, one end of which is meshed with the sample-feeding pulley, and the other end of which is tensioned in cooperation with the sample-feeding driven wheel.
[0020] According to a fully automatic liquid sample analyzer provided by the utility model, the sample delivery connection assembly includes:
[0021] The sample delivery slide rail is arranged on the sample delivery bottom plate and is parallel to the length direction of the support platform;
[0022] A sample delivery slide rail connection block is slidably disposed on the sample delivery slide rail, and the sample delivery slide rail connection block is connected to the test paper separator plate;
[0023] A sample delivery belt pressing piece, the sample delivery belt pressing piece is connected to the sample delivery slide rail connecting block and the sample delivery synchronous belt;
[0024] The sample delivery detection sheet and the sample delivery belt pressing sheet clamp the sample delivery synchronous belt, and the sample delivery detection sheet is provided with a detection identification point for detection by the sample delivery sensor.
[0025] According to a fully automatic liquid sample analyzer provided by the utility model, the rotating sample disk mechanism further includes:
[0026] Sample tray bottom plate;
[0027] A motor fixing plate, fixed to the bottom plate of the sample tray;
[0028] A sample tray motor is mounted on the motor fixing plate;
[0029] A sample tray pulley is mounted on the output shaft of the sample tray motor;
[0030] A test tube rack assembly is installed on the bottom plate of the sample tray, and a plurality of the sample tubes are placed on the test tube rack assembly;
[0031] A sample tray synchronous belt, one end of which is meshed with the sample tray belt wheel, and the other end of which is meshed with the test tube rack assembly to realize the rotation of the test tube rack assembly.
[0032] According to a fully automatic liquid sample analyzer provided by the utility model, the test tube rack assembly comprises:
[0033] A rotating shaft, the rotating shaft is fixed to the bottom plate of the sample tray;
[0034] A rotating support sleeve is mounted on the outer periphery of the rotating shaft through a bearing sleeve;
[0035] A rotating driven wheel is sleeved on the outer periphery of the rotating shaft, the upper end surface of the rotating driven wheel is connected to the rotating support sleeve, and the rotating driven wheel is meshedly connected with the sample tray synchronous belt;
[0036] A top turntable, the top turntable is connected to the upper end of the rotating support sleeve, and the top turntable is provided with two circles of circular holes distributed along the circumference for inserting the sample tube and the pipetting head;
[0037] The bottom turntable is sleeved on the outer periphery of the rotating support sleeve, the bottom turntable is connected to the top turntable via a stud, and the bottom of the sample tube and the pipetting head are placed on the bottom turntable.
[0038] According to the fully automatic liquid sample analyzer provided by the utility model, two clamping parts are arranged on the inner wall of the rotating support sleeve, there are two bearings, and a clamping ring and a bearing support ring are also mounted on the rotating shaft;
[0039] The upper end of the bearing located at the upper part of the rotating shaft is limited by the retaining ring, and the lower end is limited by the retaining part of the rotating support sleeve; the upper end of the bearing located at the lower part of the rotating shaft is limited by the retaining part of the rotating support sleeve, and the lower end is limited by the bearing support ring.
[0040] According to a fully automatic liquid sample analyzer provided by the utility model, the lower end face of the rotating driven wheel is connected to a rotating detection piece, and the outer periphery of the rotating detection piece is provided with an origin position identification point and a sample tube number identification point; the lower periphery of the rotating shaft is sleeved with a sensor mounting plate, and the sensor mounting plate is provided with an origin detection sensor for identifying the origin position identification point on the rotating detection piece and a position detection sensor for identifying the sample tube number identification point on the rotating detection piece.
[0041] According to a fully automatic liquid sample analyzer provided by the utility model, the horizontal sampling assembly comprises a horizontal bottom plate fixed to the sampling bottom plate, a horizontal motor, a horizontal driven wheel shaft and a horizontal slide rail are arranged on the horizontal bottom plate, a horizontal synchronous pulley is installed on the output shaft of the horizontal motor, a horizontal driven wheel is installed on the horizontal driven wheel shaft, the horizontal synchronous pulley and the horizontal driven wheel are connected by a horizontal synchronous belt, the horizontal slide rail is parallel to the horizontal synchronous belt, a horizontal slide rail connection block is slidably arranged on the horizontal slide rail, and the horizontal slide rail connection block is connected to the horizontal synchronous belt through a horizontal belt pressing sheet;
[0042] The vertical sampling assembly comprises a U-shaped vertical bottom plate fixed on the horizontal slide rail connection block, the vertical bottom plate is fixed with a vertically arranged lead screw motor, a nut is rotatably arranged on the output shaft of the lead screw motor, the nut is connected to the vertical slider, a sampling needle is vertically fixed on the vertical slider, and a needle guide block for the sampling needle to pass through is arranged at the lower part of the vertical bottom plate; a guide rod is vertically arranged on the U-shaped structure of the vertical bottom plate, and the guide rod passes through the vertical guide hole on the vertical slider; a vertical sensor mounting seat is fixed to the side of the vertical bottom plate, and a vertical sensor is arranged on the vertical sensor mounting seat; an optical detection module is also arranged at the lower part of the vertical bottom plate facing the horizontal slide rail connection block, for optically detecting the test strip;
[0043] A plurality of detection positions are horizontally arranged on the horizontal bottom plate, and the vertical sensor is flush with the plurality of detection positions so that position detection can be performed by the vertical sensor.
[0044] According to a fully automatic liquid sample analyzer provided by the utility model, the fully automatic liquid sample analyzer also includes a shell, and the shell includes a top plate, a bottom plate, a left door assembly, a right door assembly, a front plate, and a rear plate;
[0045] The moving direction of the test paper separator is from the right door assembly to the left door assembly, a notch is provided at a position of the support platform close to the left door assembly, a waste box is provided below the left door assembly on a side facing the right door assembly, and the waste box is located below the notch; a printing device is also provided through the left door assembly, which is suitable for printing out the analysis results of the liquid sample;
[0046] The sampling base plate is fixed between the front plate and the rear plate, the rotating sample disk mechanism is located on the side of the front plate away from the rear plate, and a window is provided on the front plate so that the sampling mechanism can sample from the rotating sample disk mechanism after passing through the window.
[0047] The utility model provides a fully automatic liquid sample analyzer, which can place multiple test strips on a supporting platform at a time, and complete fully automatic detection after being separated by the isolation groove of the test strip separator plate, thereby avoiding the test strip jamming that is easy to occur in high-speed instruments and omitting the step of manually soaking the test strips; its optical detection component and sampling mechanism share a set of motion mechanisms, which further reduces costs and reduces volume; a disposable pipetting head is used to absorb samples to prevent sample cross contamination, and at the same time simplifies the liquid path cleaning system, making it more suitable for small and medium-sized hospitals. BRIEF DESCRIPTION OF THE DRAWINGS
[0048] In order to more clearly illustrate the technical solutions in the present invention or the prior art, a brief introduction will be given below to the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.
[0049] Figure 1 It is a three-dimensional structural schematic diagram of the fully automatic liquid sample analyzer provided by the utility model;
[0050] Figure 2 It is a side view structural schematic diagram of the fully automatic liquid sample analyzer provided by the utility model;
[0051] Figure 3 It is a three-dimensional structural schematic diagram of the sample delivery mechanism provided by the utility model;
[0052] Figure 4 It is a front view structural schematic diagram of the sample delivery mechanism provided by the utility model;
[0053] Figure 5 It is a three-dimensional structural schematic diagram of the rotating sample disk mechanism provided by the utility model;
[0054] Figure 6 It is a cross-sectional structural schematic diagram of the test tube rack assembly provided by the utility model;
[0055] Figure 7 It is a three-dimensional structural schematic diagram of the sampling mechanism provided by the utility model;
[0056] Figure 8 It is a three-dimensional structural schematic diagram of the horizontal sampling assembly provided by the utility model;
[0057] Fig. 9 It is a three-dimensional structural schematic diagram of the vertical sampling assembly provided by the utility model;
[0058] Fig.10 It is a structural schematic diagram of a left door assembly provided by the utility model.
[0059] Reference numerals:
[0060] 1. Sample delivery mechanism; 101. Support platform; 102. Test paper separator; 1021. Separation slot; 103. Test paper strip; 104. Sample delivery bottom plate; 105. Support profile; 106. Sample delivery movement control component; 1061. Sample delivery motor; 1062. Sample delivery driven wheel shaft; 1063. Sample delivery pulley; 1064. Sample delivery driven wheel; 1065. Sample delivery synchronous belt; 107. Sample delivery connection component; 1071. Sample delivery slide rail; 1072. Sample delivery slide rail connection block; 1073. Sample delivery belt pressing piece; 1 074, sample delivery detection sheet; 108, sample delivery sensor; 2, rotating sample tray mechanism; 201, sample tube; 202, sample tray bottom plate; 203, motor fixing plate; 204, sample tray motor; 205, sample tray pulley; 206, test tube rack assembly; 2061, rotating shaft; 2062, rotating support sleeve; 2063, bearing; 2064, rotating driven wheel; 2065, top turntable; 2066, bottom turntable; 2067, stud; 2068, snap ring; 2069, bearing support ring; 2 0610, rotating detection plate; 20611, sensor mounting plate; 20612, origin detection sensor; 20613, position detection sensor; 207, sample plate synchronous belt; 208, pipetting head; 3, sampling mechanism; 31, sampling bottom plate; 32, horizontal sampling assembly; 321, horizontal bottom plate; 322, horizontal motor; 323, horizontal driven wheel shaft; 324, horizontal slide rail; 325, horizontal synchronous pulley; 326, horizontal driven wheel; 327, horizontal synchronous belt; 328, horizontal slide rail connection Block; 329, horizontal belt pressure plate; 33, vertical sampling assembly; 331, vertical bottom plate; 332, screw motor; 333, nut; 334, vertical slider; 335, sampling needle; 336, needle guide block; 337, guide rod; 338, vertical sensor mounting seat; 339, vertical sensor; 3310, optical detection module; 41, top plate; 42, bottom plate; 43, left door assembly; 431, waste box; 432, printing device; 44, right door assembly; 45, front plate; 46, rear plate. DETAILED DESCRIPTION
[0061] In order to make the purpose, technical solution and advantages of the utility model clearer, the technical solution of the utility model will be clearly and completely described below in conjunction with the drawings in the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0062] In the description of the embodiments of the present utility model, it should be noted that the terms "center", "longitudinal", "lateral", "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the embodiments of the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the embodiments of the present utility model. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.
[0063] In the description of the embodiments of the present utility model, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be directly connected or indirectly connected through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the embodiments of the present utility model can be understood in specific circumstances.
[0064] In the embodiments of the present invention, unless otherwise clearly specified and limited, the first feature being "above" or "below" the second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.
[0065] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the utility model embodiment. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradiction.
[0066] Combine the following Figures 1 to 10 The specific structure and working process of the fully automatic liquid sample analyzer of the utility model are described.
[0067] An embodiment of the utility model provides a fully automatic liquid sample analyzer, combined with Figure 1 and Figure 2 As shown, it includes a sample feeding mechanism 1, a rotating sample disk mechanism 2, a sampling mechanism 3 and a control device, wherein the sample feeding mechanism 1 includes a support platform 101 and a test paper separator 102 movably arranged on the support platform 101, the test paper separator 102 can move along the length direction of the support platform 101, and the test paper separator 102 is penetrated by a plurality of separation grooves 1021 along the width direction of the support platform 101, and the test paper strip 103 is placed on the support platform 101 and located in the separation groove 1021; the rotating sample disk mechanism 2 is located on the side of the length direction of the support platform 101, and the rotating sample disk mechanism 2 is placed along the rotation direction There are multiple sample tubes 201; the sampling mechanism 3 includes a sampling base plate 31, a horizontal sampling component 32 and a vertical sampling component 33. The sampling base plate 31 is vertically arranged above the sample feeding mechanism 1 and the rotating sample disk mechanism 2 along the width direction of the support platform 101, the horizontal sampling component 32 is horizontally arranged on the sampling base plate 31, and the vertical sampling component 33 is arranged on the horizontal sampling component 32, so that the horizontal position of the sample is adjusted by the horizontal sampling component 32, and the vertical position of the sample is adjusted by the vertical sampling component 33; the control device is suitable for automatically controlling the sample feeding mechanism 1, the rotating sample disk mechanism 2 and the sampling mechanism 3.
[0068] In the fully automatic liquid sample analyzer of this embodiment, during operation, the liquid sample is placed in the sample tube 201 of the rotating sample disk mechanism 2, and the rotating sample disk mechanism 2 is controlled by the control device to rotate so that the sample tube 201 to be detected is rotated to the sampling position, and then the control device controls the horizontal sampling component 32 and the vertical sampling component 33 of the sampling mechanism 3 to adjust the horizontal and vertical directions, and finally the sample tube 201 at the sampling position is sampled, and then adjusted by the horizontal sampling component 32 and the vertical sampling component 33 to reach the test strip 103 of the sample delivery mechanism 1. It should be understood that in the sample delivery mechanism 1 of this embodiment, the test strip 103 is placed on the support platform 101 and is located in the separation groove 1021. The test strip separator 102 is adjusted to move on the support platform 101 by the control device. During the movement of the test strip separator 102, the test strip 103 is pushed to move on the support platform 101. Since the test strip separator 102 isolates and separates multiple test strips 103, a single test strip 103 can be dripped and tested in an orderly manner. After the monitoring and analysis is completed, as the test strip separator 102 moves, the test strip 103 after the test and analysis is moved out of the support platform 101 and falls into the waste box, completing the fully automatic detection. The whole process not only avoids the test strip jam that is easy to occur in high-speed instruments, but also omits the step of manually soaking the test strip. The detection speed is between that of high-speed instruments and low-speed instruments, and is suitable for small and medium-sized hospitals.
[0069] It should be understood that the control device used in this embodiment can use a PLC programmable controller, and the control process can be implemented using existing technology, which will not be described in detail here. The following is a further description of the sample feeding mechanism 1, the rotating sample disk mechanism 2 and the sampling mechanism 3 in conjunction with the specific embodiment structure.
[0070] In some embodiments, in combination Figure 3 and Figure 4 As shown, a sample delivery mechanism 1 of a fully automatic liquid sample analyzer of the utility model includes a support platform 101, a test paper separator 102, a sample delivery base plate 104, a sample delivery movement control component 106, a sample delivery connection component 107 and a sample delivery sensor 108, wherein the support platform 101 is installed on the sample delivery base plate 104 through a support profile 105; the sample delivery movement control component 106 is installed on the sample delivery base plate 104; the sample delivery connection component 107 connects the test paper separator 102 and the sample delivery movement control component 106; the sample delivery sensor 108 is fixed on the sample delivery base plate 104, and is used to detect the position of the test paper separator 102.
[0071] The sample delivery movement control component 106 is controlled and adjusted by the control device. The sample delivery movement control component 106 adjusts the test paper separator 102 through the sample delivery connection component 107. The sample delivery movement control component 106 and the sample delivery connection component 107 can be various control and connection structures. For example, the sample delivery movement control component 106 can adopt electric telescopic, connecting rod control and other structures, and the sample delivery connection component 107 can also be some conventional connection structures, which are not listed here one by one.
[0072] In some specific examples, the sample delivery movement and control component 106 includes a sample delivery motor 1061, a sample delivery driven wheel shaft 1062, a sample delivery pulley 1063, a sample delivery driven wheel 1064 and a sample delivery synchronous belt 1065, wherein the sample delivery motor 1061 and the sample delivery driven wheel shaft 1062 are fixed on the sample delivery base plate 104, and the connecting line of the sample delivery motor 1061 and the sample delivery driven wheel shaft 1062 is kept parallel to the length direction of the support platform 101; the sample delivery pulley 1063 is fixed on the output shaft of the sample delivery motor 1061, and the sample delivery driven wheel 1064 is fixed on the sample delivery driven wheel shaft 1062; one end of the sample delivery synchronous belt 1065 is meshed with the sample delivery pulley 1063, and the other end is tightened with the sample delivery driven wheel 1064.
[0073] The sample feeding motor 1061 drives the sample feeding pulley 1063 to rotate, and the sample feeding pulley 1063 is connected to the sample feeding timing belt 1065. The other end of the sample feeding timing belt 1065 is tensioned by the sample feeding driven wheel 1064. As the sample feeding motor 1061 works, the sample feeding timing belt 1065 moves. The sample feeding timing belt 1065 can drive the test paper separator 102 to move on the supporting platform 101 through the sample feeding connecting assembly 107, thereby moving the test paper strip 103.
[0074] In some specific examples, the sample delivery connection component 107 includes a sample delivery rail 1071, a sample delivery rail connecting block 1072, a sample delivery belt pressing plate 1073 and a sample delivery detection plate 1074, wherein the sample delivery rail 1071 is arranged on the sample delivery base plate 104 and remains parallel to the length direction of the support platform 101; the sample delivery rail connecting block 1072 is slidably arranged on the sample delivery rail 1071, and the sample delivery rail connecting block 1072 is connected to the test paper separator 102; the sample delivery belt pressing plate 1073 connects the sample delivery rail connecting block 1072 and the sample delivery synchronous belt 1065; the sample delivery detection plate 1074 and the sample delivery belt pressing plate 1073 clamp the sample delivery synchronous belt 1065, and the sample delivery detection plate 1074 is provided with a detection identification point for detection by the sample delivery sensor 108.
[0075] When the sample delivery motor 1061 is started, the sample delivery slide rail connection block 1072 will move with the sample delivery synchronous belt 1065, thereby driving the test paper separator 102 to push the test paper strip 103 on the support platform 101 to move along the sample delivery slide rail 1071, and reach the sample loading position and the light measuring position in turn. After the optical detection is completed, the sample delivery motor 1061 is started again to move the tested test paper strip 103 outside the support platform 101, and finally drop it into the waste box. In the above process, the sample delivery sensor 108 can detect whether the test paper separator 102 is located at the origin by detecting the sample delivery detection sheet 1074.
[0076] In some embodiments, in combination Figure 5 and Figure 6 As shown, a rotating sample disk mechanism 2 of a fully automatic liquid sample analyzer of the present invention comprises a sample disk bottom plate 202, a motor fixing plate 203, a sample disk motor 204, a sample disk pulley 205, a test tube rack assembly 206 and a sample disk synchronous belt 207, wherein the motor fixing plate 203 is fixed to the sample disk bottom plate 202; the sample disk motor 204 is mounted on the motor fixing plate 203; the sample disk pulley 205 is mounted on the output shaft of the sample disk motor 204; the test tube rack assembly 206 is mounted on the sample disk bottom plate 202, and a plurality of sample tubes 201 are placed on the test tube rack assembly 206; one end of the sample disk synchronous belt 207 is meshed with the sample disk pulley 205, and the other end is meshed with the test tube rack assembly 206, so as to realize the rotation of the test tube rack assembly 206.
[0077] In some specific examples, the test tube rack assembly 206 includes a rotating shaft 2061, a rotating support sleeve 2062, a rotating driven wheel 2064, a top turntable 2065 and a bottom turntable 2066, wherein the rotating shaft 2061 is fixed to the sample tray bottom plate 202; the rotating support sleeve 2062 is sleeved on the outer periphery of the rotating shaft 2061 through a bearing 2063; the rotating driven wheel 2064 is sleeved on the outer periphery of the rotating shaft 2061, and the upper end surface of the rotating driven wheel 2064 is connected to the rotating support sleeve 2062. The rotating driven wheel 2064 is meshedly connected with the sample disk synchronous belt 207; the top turntable 2065 is connected to the upper end of the rotating support sleeve 2062, and two circles of circular holes are distributed circumferentially on the top turntable 2065 for inserting the sample tube 201 and the pipetting head 208; the bottom turntable 2066 is sleeved on the outer periphery of the rotating support sleeve 2062, and the bottom turntable 2066 is connected to the top turntable 2065 by the stud 2067, and the bottom of the sample tube 201 and the pipetting head 208 are placed on the bottom turntable 2066. Two locking parts are arranged on the inner wall of the rotating support sleeve 2062, there are two bearings 2063, and a retaining ring 2068 and a bearing support ring 2069 are also mounted on the rotating shaft 2061; the upper end of the bearing 2063 located at the upper part of the rotating shaft 2061 is limited by the retaining ring 2068, and the lower end is limited by the locking part of the rotating support sleeve 2062; the upper end of the bearing 2063 located at the lower part of the rotating shaft 2061 is limited by the locking part of the rotating support sleeve 2062, and the lower end is limited by the bearing support ring 2069. The lower end face of the rotating driven wheel 2064 is connected to a rotating detection piece 20610, and an origin position identification point and a sample tube number identification point are arranged on the periphery of the rotating detection piece 20610; a sensor mounting plate 20611 is mounted on the lower periphery of the rotating shaft 2061, and an origin detection sensor 20612 for identifying the origin position identification point on the rotating detection piece 20610 and a position detection sensor 20613 for identifying the sample tube number identification point on the rotating detection piece 20610 are arranged on the sensor mounting plate 20611.
[0078] In the above structure, a motor fixing plate 203 and a test tube rack assembly 206 are mounted on the sample tray bottom plate 202; the sample tray motor 204 and the motor fixing plate 203 are connected by screws; the sample tray pulley 205 is fixed to the sample tray motor 204 by a top screw; one end of the sample tray synchronous belt 207 is meshed with the sample tray motor 204, and the other end is meshed with the rotating driven wheel 2064 in the test tube rack assembly 206. The rotating shaft 2061, the top turntable 2065, the rotating support sleeve 2062, the bearing 2063, the bearing support ring 2069, the rotating driven wheel 2064, and the rotating detection piece 20610 are concentrically assembled; the sensor mounting plate 20611 and the rotating shaft 2061 are connected by screws, and an origin detection sensor 20612 and a position detection sensor 20613 are installed thereon; the bearing support ring 2069 is fixed on the rotating shaft 2061 by a top screw; the rotating detection piece 20610, the rotating driven wheel 2064 and the rotating support sleeve 2062 are all connected by screws; the top turntable 2065 is connected to the top of the rotating support sleeve 2062 by screws; the bottom turntable 2066 is connected to the top turntable 2065 by a stud 2067; the upper part of the sample tube 201 is fixed by the top turntable 2065, and the lower part is supported by the bottom turntable 2066; the disposable pipetting head 208 is placed in the top turntable 2065. When the sample tray motor 204 is started, the rotating driven wheel 2064 follows the sample tray synchronous belt 207 to move, thereby driving the test tube rack assembly 206 to rotate along the rotating shaft 2061, rotating the required sample tube 201 and the disposable pipetting head 208 to the sample aspiration position for the sampling needle to perform the sample aspiration action.
[0079] It should be understood that in the above process, the origin detection sensor 20612 is used to determine whether the disposable pipetting head 208 and the sample tube 201 are in the initial position; the position detection sensor 20613 is used to determine which sample tube 201 is currently in the sampling state.
[0080] In some embodiments, in combination Figure 7 , Figure 8 and Fig. 9 As shown, according to a fully automatic liquid sample analyzer provided by the utility model, the horizontal sampling component 32 includes a horizontal base plate 321 fixed to the sampling base plate 31, and a horizontal motor 322, a horizontal driven wheel shaft 323 and a horizontal slide rail 324 are arranged on the horizontal base plate 321. A horizontal synchronous pulley 325 is installed on the output shaft of the horizontal motor 322, and a horizontal driven wheel 326 is installed on the horizontal driven wheel shaft 323. The horizontal synchronous pulley 325 and the horizontal driven wheel 326 are connected by a horizontal synchronous belt 327. The horizontal slide rail 324 is parallel to the horizontal synchronous belt 327. A horizontal slide rail connecting block 328 is slidably arranged on the horizontal slide rail 324, and the horizontal slide rail connecting block 328 is connected to the horizontal synchronous belt 327 through a horizontal belt pressing plate 329.
[0081] In the above structure, see Figure 8 As shown, a horizontal motor 322, a horizontal driven wheel shaft 323 and a horizontal slide rail 324 are installed on the horizontal base plate 321; the horizontal driven wheel 326 is concentrically assembled with the horizontal driven wheel shaft 323; the horizontal synchronous pulley 325 is fixed to the horizontal motor 322 by a top screw; one end of the horizontal synchronous belt 327 is meshed with the horizontal synchronous pulley 325, and the other end is tensioned by the horizontal driven wheel 326; the horizontal slide rail connecting block 328 is slidably set on the horizontal slide rail 324; the horizontal belt pressing piece 329 is fixed on the horizontal slide rail connecting block 328, and its function is to press the horizontal synchronous belt 327 and the horizontal slide rail connecting block 328; when the horizontal motor 322 is started, the horizontal slide rail connecting block 328 will follow the horizontal synchronous belt 327 to move, thereby driving the vertical sampling component 33 to move in the horizontal direction.
[0082] In some specific examples, the vertical sampling assembly 33 includes a U-shaped vertical base plate 331 fixed on the horizontal slide rail connection block 328, the vertical base plate 331 is fixed with a vertically arranged lead screw motor 332, a nut 333 is rotatably arranged on the output shaft of the lead screw motor 332, the nut 333 is connected to a vertical slider 334, a sampling needle 335 is vertically fixed on the vertical slider 334, and a needle guide block 336 for the sampling needle 335 to pass through is arranged at the lower part of the vertical base plate 331; a guide rod 337 is vertically arranged on the U-shaped structure of the vertical base plate 331, and the guide rod 337 is passed through the vertical guide hole on the vertical slider 334; a vertical sensor mounting seat 338 is fixed to the side of the vertical base plate 331, and a vertical sensor 339 is arranged on the vertical sensor mounting seat 338; an optical detection module 3310 is also arranged on the lower part of the vertical base plate 331 facing the horizontal slide rail connection block 328, which is used to perform optical detection on the test strip 103.
[0083] In the above structure, see Fig. 9 As shown, the vertical bottom plate 331 is equipped with a vertical sensor mounting seat 338, a needle guide block 336, a lead screw motor 332 and an optical detection module 3310; the vertical slider 334 is fixed on the nut 333, and a sampling needle 335 is installed on the left side thereof, and the right side is concentrically assembled with the guide rod 337; the guide rod 337 is used to ensure that the vertical slider 334 moves along the direction of the guide rod 337; the needle guide block 336 plays a guiding role to ensure that the sampling needle 335 moves in the vertical direction; the vertical sensor 339 is installed on the vertical sensor mounting seat 338. When the lead screw motor 332 is started, the vertical slider 334 moves axially along the output shaft of the lead screw motor 332 under the joint action of the nut 2032 and the guide rod 337, thereby driving the sampling needle 335 to move in the vertical direction.
[0084] It should be understood that the function of the vertical sensor 339 is to determine the horizontal position of the sampling component. Multiple detection positions can be set at the notch of the bent edge on the upper side of the horizontal bottom plate 321. The vertical sensor 339 is flush with the multiple detection positions. The detection positions include at least the pipette head position, the sample tube position, the optical detection initial position, the sampling component dripping initial position, the sampling component dripping cut-off position, etc., which guide the moving position of the vertical sampling component 33 in each stage in turn.
[0085] Combination Figure 1 and Figure 2 As shown, the fully automatic liquid sample analyzer provided by the present invention, in other embodiments, further includes a housing, the housing including a top plate 41, a bottom plate 42, a left door assembly 43, a right door assembly 44, a front plate 45, and a rear plate 46. The moving direction of the test paper separator 102 is from the right door assembly 44 to the left door assembly 43, and a notch is provided at the position of the support platform 101 near the left door assembly 43, see Fig.10 As shown, a waste box 431 is provided at the lower part of the left door assembly 43 facing the right door assembly 44, and the waste box 431 is located below the notch; a printing device 432 is also provided through the left door assembly 43, which is suitable for printing out the analysis results of the liquid sample; the sampling base plate 31 is fixed between the front plate 45 and the rear plate 46, the rotating sample disk mechanism 2 is located on the side of the front plate 45 away from the rear plate 46, and a window is provided on the front plate 45, so that the sampling mechanism 3 can sample from the rotating sample disk mechanism 2 after passing through the window.
[0086] For some specific examples, see Figure 1As shown, the sample feeding mechanism 1, the front plate 45, the rotating sample disk mechanism 2 and the rear plate 46 are all fixed on the bottom plate 42; the left door assembly 43 and the right door assembly 44 are fixed on the rear plate 46 on one side, and overlapped with the front plate 45 on the other side; the top plate 41 is fixed on the rear plate 46 on one side, and overlapped with the left door assembly 43, the right door assembly 44 and the front plate 45 on the other side; the sampling mechanism 3 is fixed on the rear plate 46 on one side, and fixed on the front plate 45 on the other side. The operator first places the test strips 103 on the support platform 101 in sequence and separates them by the isolation groove 1021 of the test strip separator 102; after the detection starts, the sample feeding motor 1061 starts to drive the test strip separator 102 to move, thereby driving the test strip 103 to move to the sample adding position; at the same time, the sample tray motor 204 starts to drive the test tube rack assembly 206 to rotate through the sample tray synchronous belt 207, so that the sample tube 201 rotates to the sample aspiration position, and the aspiration is completed under the joint action of the horizontal motor 322 and the screw motor 332. The disposable pipette head 208 is attached and the sample is sucked, and then moved to the sample adding position for sample adding; after the sample adding action is completed, the sample feeding motor 1061 is started, driving the sampled test strip 103 to the light measuring position; at the same time, the sampling mechanism 3 is started, and the used disposable pipette head 208 is put back into the test tube rack assembly 206; after the reaction is completed, the sampling mechanism 3 is started, driving the optical detection module 3310 to start optical detection, converting the received light signal into an electrical signal, and finally outputting the detection result through the printing device 432. After the optical detection is completed, the sample feeding motor 1061 is started again, driving the tested test strip 103 to move until it is separated from the support platform 101 and finally falls into the waste box 431.
[0087] In summary, the fully automatic liquid sample analyzer of the utility model can place multiple test strips on the supporting platform at a time, and complete the fully automatic detection after being separated by the isolation groove of the test strip separator plate, which not only avoids the test strip jam that is easy to occur in high-speed instruments, but also omits the step of manually soaking the test strips; its optical detection component and sampling mechanism share a set of motion mechanisms, which further reduces the cost and size; a disposable pipette head is used to absorb the sample to prevent the cross contamination of the sample, and at the same time simplifies the liquid path cleaning system, which is more suitable for small and medium-sized hospitals.
[0088] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the utility model.
Claims
1. A fully automatic liquid sample analyzer, characterized in that: include: A sample delivery mechanism (1) comprises a support platform (101) and a test paper separator (102) movably arranged on the support platform (101); the test paper separator (102) can move along the length direction of the support platform (101); a plurality of separation grooves (1021) are arranged on the test paper separator (102) along the width direction of the support platform (101); a test paper strip (103) is placed on the support platform (101) and is located in the separation groove (1021); A rotating sample disk mechanism (2) is located on the side of the support platform (101) in the length direction, and a plurality of sample tubes (201) are placed on the rotating sample disk mechanism (2) along the rotation direction; The sampling mechanism (3) comprises a sampling base plate (31), a horizontal sampling assembly (32) and a vertical sampling assembly (33), wherein the sampling base plate (31) is vertically arranged above the sample feeding mechanism (1) and the rotating sample disk mechanism (2) along the width direction of the supporting platform (101), the horizontal sampling assembly (32) is horizontally arranged on the sampling base plate (31), and the vertical sampling assembly (33) is arranged on the horizontal sampling assembly (32), so that the horizontal position of the sample is adjusted by the horizontal sampling assembly (32), and the vertical position of the sample is adjusted by the vertical sampling assembly (33); The control device is suitable for automatically controlling the sample delivery mechanism (1), the rotating sample disk mechanism (2) and the sampling mechanism (3).
2. The fully automatic liquid sample analyzer according to claim 1, characterized in that: The sample delivery mechanism (1) further comprises: A sample delivery base plate (104), the support platform (101) being mounted on the sample delivery base plate (104) via a support profile (105); A sample delivery movement control component (106) is installed on the sample delivery base plate (104); A sample delivery connection component (107) connected to the test paper separation plate (102) and the sample delivery movement control component (106); A sample delivery sensor (108) is fixed on the sample delivery bottom plate (104) and is used to detect the position of the test paper separation plate (102).
3. The fully automatic liquid sample analyzer according to claim 2, characterized in that: The sample delivery movement control component (106) comprises: The sample delivery motor (1061) and the sample delivery driven wheel shaft (1062) are fixed on the sample delivery bottom plate (104), and the connecting line between the sample delivery motor (1061) and the sample delivery driven wheel shaft (1062) is kept parallel to the length direction of the support platform (101); A sample delivery pulley (1063) and a sample delivery driven wheel (1064), wherein the sample delivery pulley (1063) is fixed on the output shaft of the sample delivery motor (1061), and the sample delivery driven wheel (1064) is fixed on the sample delivery driven wheel shaft (1062); A sample delivery synchronous belt (1065), one end of which is meshed with the sample delivery pulley (1063), and the other end of which is tensioned in cooperation with the sample delivery driven wheel (1064).
4. The fully automatic liquid sample analyzer according to claim 3, characterized in that: The sample delivery connection assembly (107) comprises: A sample delivery slide rail (1071) is arranged on the sample delivery base plate (104) and is parallel to the length direction of the support platform (101); A sample delivery slide rail connection block (1072), slidably disposed on the sample delivery slide rail (1071), the sample delivery slide rail connection block (1072) being connected to the test paper separator plate (102); A sample delivery belt pressing piece (1073), wherein the sample delivery belt pressing piece (1073) connects the sample delivery slide rail connecting block (1072) and the sample delivery synchronous belt (1065); A sample delivery detection sheet (1074), wherein the sample delivery detection sheet (1074) and the sample delivery belt pressing sheet (1073) clamp the sample delivery synchronous belt (1065), and a detection identification point for detection by the sample delivery sensor (108) is arranged on the sample delivery detection sheet (1074).
5. The fully automatic liquid sample analyzer according to claim 1, characterized in that: The rotating sample disk mechanism (2) further comprises: Sample tray bottom plate (202); A motor fixing plate (203) fixed to the sample tray bottom plate (202); A sample tray motor (204) mounted on the motor fixing plate (203); A sample tray pulley (205) mounted on the output shaft of the sample tray motor (204); A test tube rack assembly (206) is installed on the sample tray bottom plate (202), and a plurality of sample tubes (201) are placed on the test tube rack assembly (206); A sample tray synchronous belt (207), one end of which is meshed with the sample tray belt wheel (205), and the other end of which is meshed with the test tube rack assembly (206) to realize the rotation of the test tube rack assembly (206).
6. The fully automatic liquid sample analyzer according to claim 5, characterized in that: The test tube rack assembly (206) comprises: A rotating shaft (2061), wherein the rotating shaft (2061) is fixed to the sample tray bottom plate (202); A rotating support sleeve (2062) is sleeved on the outer periphery of the rotating shaft (2061) via a bearing (2063); A rotating driven wheel (2064) is sleeved on the outer circumference of the rotating shaft (2061), the upper end surface of the rotating driven wheel (2064) is connected to the rotating support sleeve (2062), and the rotating driven wheel (2064) is meshingly connected to the sample tray synchronous belt (207); A top turntable (2065), the top turntable (2065) is connected to the upper end of the rotating support sleeve (2062), and the top turntable (2065) is provided with two circles of circular holes distributed along the circumference, for inserting the sample tube (201) and the pipetting head (208); The bottom turntable (2066) is mounted on the outer periphery of the rotating support sleeve (2062), the bottom turntable (2066) is connected to the top turntable (2065) via a stud (2067), and the bottom of the sample tube (201) and the pipetting head (208) are placed on the bottom turntable (2066).
7. The fully automatic liquid sample analyzer according to claim 6, characterized in that: The inner wall of the rotating support sleeve (2062) is provided with two locking portions, the bearings (2063) are provided with two, and the rotating shaft (2061) is also provided with a retaining ring (2068) and a bearing support ring (2069); The upper end of the bearing (2063) located at the upper part of the rotating shaft (2061) is limited by the retaining ring (2068), and the lower end is limited by the retaining portion of the rotating support sleeve (2062); the upper end of the bearing (2063) located at the lower part of the rotating shaft (2061) is limited by the retaining portion of the rotating support sleeve (2062), and the lower end is limited by the bearing support ring (2069).
8. The fully automatic liquid sample analyzer according to claim 6, characterized in that: The lower end surface of the rotating driven wheel (2064) is connected to a rotating detection piece (20610), and the outer periphery of the rotating detection piece (20610) is provided with an origin position identification point and a sample tube number identification point; the lower outer periphery of the rotating shaft (2061) is provided with a sensor mounting plate (20611), and the sensor mounting plate (20611) is provided with an origin detection sensor (20612) for identifying the origin position identification point on the rotating detection piece (20610) and a position detection sensor (20613) for identifying the sample tube number identification point on the rotating detection piece (20610).
9. The fully automatic liquid sample analyzer according to claim 1, characterized in that: The horizontal sampling assembly (32) comprises a horizontal base plate (321) fixed to the sampling base plate (31); a horizontal motor (322), a horizontal driven wheel shaft (323) and a horizontal slide rail (324) are arranged on the horizontal base plate (321); a horizontal synchronous pulley (325) is installed on the output shaft of the horizontal motor (322); a horizontal driven wheel (326) is installed on the horizontal driven wheel shaft (323); the horizontal synchronous pulley (325) and the horizontal driven wheel (326) are connected via a horizontal synchronous belt (327); the horizontal slide rail (324) is parallel to the horizontal synchronous belt (327); a horizontal slide rail connection block (328) is slidably arranged on the horizontal slide rail (324); the horizontal slide rail connection block (328) is connected to the horizontal synchronous belt (327) via a horizontal belt pressing sheet (329); The vertical sampling assembly (33) comprises a U-shaped vertical bottom plate (331) fixed on the horizontal slide rail connection block (328), a vertically arranged lead screw motor (332) is fixed on the vertical bottom plate (331), a screw nut (333) is rotatably arranged on the output shaft of the lead screw motor (332), the screw nut (333) is connected to a vertical slide block (334), a sampling needle (335) is vertically fixed on the vertical slide block (334), and a needle guide block (336) for the sampling needle (335) to pass through is arranged at the lower part of the vertical bottom plate (331). ); the U-shaped structure of the vertical bottom plate (331) is vertically provided with a guide rod (337), and the guide rod (337) is passed through the vertical guide hole on the vertical slide block (334); a vertical sensor mounting seat (338) is fixed on the side of the vertical bottom plate (331), and a vertical sensor (339) is arranged on the vertical sensor mounting seat (338); an optical detection module (3310) is also arranged on the side of the lower part of the vertical bottom plate (331) facing the horizontal slide rail connection block (328), which is used to perform optical detection on the test strip (103); A plurality of detection positions are horizontally arranged on the horizontal bottom plate (321), and the vertical sensor (339) is flush with the plurality of detection positions so that position detection can be performed through the vertical sensor (339).
10. The fully automatic liquid sample analyzer according to any one of claims 1 to 9, characterized in that: The fully automatic liquid sample analyzer further comprises a housing, wherein the housing comprises a top plate (41), a bottom plate (42), a left door assembly (43), a right door assembly (44), a front plate (45), and a rear plate (46); The moving direction of the test paper separator (102) is from the right door assembly (44) to the left door assembly (43); a notch is provided at a position of the support platform (101) close to the left door assembly (43); a waste box (431) is provided below a side of the left door assembly (43) facing the right door assembly (44); the waste box (431) is located below the notch; a printing device (432) is also provided through the left door assembly (43) for printing out the analysis results of the liquid sample; The sampling base plate (31) is fixed between the front plate (45) and the rear plate (46); the rotating sample disk mechanism (2) is located on a side of the front plate (45) away from the rear plate (46); and a window is provided on the front plate (45) so that the sampling mechanism (3) can sample from the rotating sample disk mechanism (2) after passing through the window.
Citation Information
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