Immune cell centrifugal device

By designing convenient disassembly and assembly components and connecting components in the immune cell centrifugal device, the problem of difficult disassembly and cleaning of the blocking block and inconsistent rotation of the two-way threaded screw is solved, and the convenient operation of the blocking block and the stability of the test tube clamping are achieved.

CN222642260UActive Publication Date: 2025-03-21SHENZHEN HORNETCORN BIOTECH
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Patent Information

Application Number
CN202421265248.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-05
Publication Date
2025-03-21
Estimated Expiration
2034-06-05

AI Technical Summary

Technical Problem

When used in existing immune cell centrifugal devices, the sealing block is difficult to disassemble and clean, and the two-way threaded screw rotates inconsistently, making it easy to get stuck.

Method used

The convenient disassembly and assembly components are designed, including disassembly and assembly seats, square insertion rods, clamping blocks, tie rods, clamping sliders and clamping springs, to achieve convenient disassembly and assembly and cleaning of the sealing blocks; at the same time, by connecting the tapered gears and rotating handles in the assembly, the bidirectional threaded screws are rotated simultaneously, and the clamping frame is driven to clamp and fix the test tube.

Benefits of technology

It realizes convenient disassembly and assembly and cleaning of the sealing block, avoiding the problem of solution residue; at the same time, it ensures the coordinated rotation of the bidirectional threaded screw, and improves the stability of test tube clamping and practical use.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an immune cell centrifugal device, which belongs to the technical field of cell centrifugation and comprises a centrifugal device body, a stabilizing mechanism is arranged below the centrifugal device body, a cover plate is arranged above the centrifugal device body, a convenient disassembly and assembly component is arranged in the middle of the cover plate, and a plugging block is arranged below the convenient disassembly and assembly component. A centrifugal seat is arranged in the centrifugal device body, a clamping seat is arranged in the centrifugal seat, two-way threaded lead screws are arranged on the two sides of the interior of the clamping seat, a connecting assembly is arranged at one end of each two-way threaded lead screw, and clamping frames are symmetrically connected to the surfaces of the two-way threaded lead screws in a threaded mode. And a fastening seat, a fastening plate and a fastening spring are arranged, so that the blocking effect of the blocking block on the test tube is good, a connecting assembly is arranged, two bidirectional threaded lead screws can rotate at the same time, and therefore a clamping frame is driven to clamp and fix the test tube.
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Description

Technical Field

[0001] The utility model belongs to the technical field of cell centrifugation, and in particular relates to an immune cell centrifugation device. Background Art

[0002] Cell centrifugation is a basic method for studying the nucleus, mitochondria, Golgi apparatus, lysosomes and microsomes, as well as various macromolecules. It uses the centrifugal force of a high-speed rotating object to cause suspended particles in the rotating body to settle or float, thereby concentrating certain particles or separating them from other particles.

[0003] Chinese patent application No. 202221189132.X discloses an immune cell centrifuge device, which relates to the field of cell centrifugation technology, and includes a centrifuge main body, a test tube clamping mechanism is arranged on the inner wall of the centrifuge main body, a stabilizing mechanism is arranged on the lower bottom surface of the centrifuge main body, and the test tube clamping mechanism includes a centrifugal shaft, and the outer surface of the centrifugal shaft is rotatably connected with a connecting column, and the outer surface of the connecting column away from the centrifugal shaft is fixedly connected with a clamping box. The utility model adopts a fixed seat, a connecting rod, a clamping box, a rubber gasket and a clamping frame to cooperate with each other, and uses the clamping frame in the clamping box to clamp the test tube containing immune cells, and uses the rubber gasket to clamp and protect the outer surface of the glass test tube to prevent the test tube from breaking during centrifugal operation, thereby solving the problem of effective clamping of the test tube containing immune cells and causing solution splashing, thereby achieving the effect of improving the accuracy of the centrifuge data.

[0004] The above-mentioned patent disclosed, 1. When in use, a sealing block is set on the cover plate to seal the test tube, but when in use, the sealing block cannot be disassembled and cleaned, and after use, the solution will adhere to it; 2. When in use, the clamping frame is driven to move by rotating two driving rods to clamp and fix the test tube, but when in use, the two driving rods need to be rotated at the same time, and then the test tube is placed in and fixed, but when rotating, it is easy to rotate at different times, resulting in jamming. Utility Model Content

[0005] In order to solve the problems raised in the above background technology, the utility model provides an immune cell centrifugal device, which has the characteristics of being easy to disassemble and assemble the blocking block, cleaning the blocking block, and enabling two fixing bolts to rotate simultaneously.

[0006] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: an immune cell centrifuge device, comprising a centrifuge body, a stabilizing mechanism is arranged below the centrifuge body, a cover plate is arranged above the centrifuge body, a convenient disassembly and assembly component is arranged in the middle of the cover plate, a sealing block is arranged below the convenient disassembly and assembly component, a centrifugal seat is arranged inside the centrifugal body, a clamping seat is arranged inside the centrifugal seat, two sides of the clamping seat are provided with bidirectional threaded screws, one end of the bidirectional threaded screw is provided with a connecting assembly, the surface of the bidirectional threaded screw is symmetrical and is threadedly connected to a clamping frame.

[0007] Preferably, the convenient disassembly and assembly component includes a disassembly and assembly seat, a square plug-in rod, a clamping block, a pull rod, a clamping slide block and a clamping spring, wherein a disassembly and assembly seat is arranged in the middle of the cover plate, a square plug-in rod is inserted below the disassembly and assembly seat, a clamping block is arranged on one side of the square plug-in rod, a pull rod is arranged at one end of the clamping block, a clamping slide block is arranged above the pull rod, and a clamping spring is arranged on one side of the clamping slide block.

[0008] Preferably, a fastening seat is provided at one end of the square plug rod, a fastening plate is provided inside the fastening seat, a fastening spring is provided at the connection between the fastening seat and the fastening plate, limiting sliders are provided on both sides of the fastening plate, and the middle sliding connection of the limiting slider is connected to the limiting slide rod.

[0009] Preferably, a guide sliding opening is provided at one end of the clamping block, and a clamping hole matching the clamping block is provided at one side of the square plug rod.

[0010] Preferably, one end of the clamping slider is slidably connected to a stabilizing slide rod, and a bearing is provided at the connection between the square insert rod and the fastening seat.

[0011] Preferably, the connecting assembly includes a connecting seat, a rotating rod, bevel gear one, bevel gear two and a turning handle, wherein a connecting seat is provided on one side of the clamping seat, a rotating rod is provided inside the connecting seat, a turning handle is provided at one end of the rotating rod, bevel gear one is provided above the rotating rod, and one side of the bevel gear one is meshingly connected with bevel gear two.

[0012] Preferably, a support rod is provided on the surface of the turning handle, and the support rod is arranged in a surrounding manner.

[0013] Preferably, the rotating rod and the connecting seat are rotatably connected via a bearing, and one end of the bidirectional threaded screw and the connecting seat are also rotatably connected via a bearing.

[0014] Compared with the prior art, the beneficial effects of the utility model are:

[0015] 1. The utility model realizes the effect of facilitating the disassembly and assembly of the sealing block and cleaning the sealing block by providing a convenient disassembly and assembly component. A disassembly and assembly seat, a square plug rod, a clamping block, a pull rod, a clamping slide block and a clamping spring are provided, so that the sealing block can be conveniently disassembled and assembled, and the sealing block can be cleaned. A fastening seat, a fastening plate and a fastening spring are provided, so that the sealing block has a good effect on sealing the test tube.

[0016] 2. The utility model realizes the effect that two bidirectional threaded screws can rotate simultaneously by setting a connecting component, thereby driving the clamping frame to clamp and fix the test tube. The connecting seat rotating rod, bevel gear 1, bevel gear 2 and turning handle are set, so that the two bidirectional threaded screws can rotate simultaneously, thereby driving the clamping frame to move and clamp and fix the test tube, thereby improving the practicality of use. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0018] Figure 2 It is a schematic diagram of the structure of the utility model cut from the front view;

[0019] Figure 3 It is a schematic diagram of the structure of the utility model cut from top view;

[0020] Figure 4 This is a schematic diagram of the structure of the convenient disassembly and assembly components of the utility model;

[0021] Figure 5 This is a schematic diagram of the structure of the utility model at point A in the main view section;

[0022] Figure 6 It is a structural schematic diagram of the connection component of the utility model.

[0023] In the figure: 1. centrifugal device body; 2. stabilizing mechanism; 3. cover plate; 4. convenient disassembly and assembly component; 41. disassembly and assembly seat; 42. square plug rod; 43. clamping block; 44. pull rod; 45. clamping slide block; 46. clamping spring; 411. fastening seat; 412. fastening plate; 413. fastening spring; 414. limit slide block; 415. limit slide rod; 5. blocking block; 6. centrifugal seat; 7. clamping seat; 8. two-way threaded screw; 9. connecting assembly; 91. connecting seat; 92. rotating rod; 93. bevel gear one; 94. bevel gear two; 95. turning handle; 96. support rod; 10. clamping frame. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] Example 1

[0026] See also Figure 1-6 The utility model provides the following technical solutions: an immune cell centrifuge device, comprising a centrifuge body 1, a stabilizing mechanism 2 is arranged below the centrifuge body 1, a cover plate 3 is arranged above the centrifuge body 1, a convenient disassembly and assembly component 4 is arranged in the middle of the cover plate 3, a blocking block 5 is arranged below the convenient disassembly and assembly component 4, a centrifuge seat 6 is arranged inside the centrifuge body 1, a clamping seat 7 is arranged inside the centrifuge seat 6, two-way threaded screws 8 are arranged on both sides of the inside of the clamping seat 7, a connecting component 9 is arranged at one end of the two-way threaded screw 8, and the surface of the two-way threaded screw 8 is symmetrical and is threadedly connected to a clamping frame 10.

[0027] Specifically, the convenient disassembly and assembly component 4 includes a disassembly and assembly seat 41, a square plug rod 42, a clamping block 43, a pull rod 44, a clamping slide 45 and a clamping spring 46, wherein a disassembly and assembly seat 41 is arranged in the middle of the cover plate 3, a square plug rod 42 is inserted below the disassembly and assembly seat 41, a clamping block 43 is arranged on one side of the square plug rod 42, a pull rod 44 is arranged at one end of the clamping block 43, a clamping slide 45 is arranged above the pull rod 44, and a clamping spring 46 is arranged on one side of the clamping slide 45.

[0028] By adopting the above technical solution, the pull rod 44 is pulled, and the pull rod 44 drives the clamping slider 45 to move and compress the clamping spring 46, so that the clamping block 43 is disengaged from the clamping hole, so that the square plug rod 42 and the disassembly seat 41 can be separated, so that the blocking block 5 can be removed and cleaned, so that when the device is in use, it is convenient to disassemble and assemble the blocking block 5, and clean the blocking block 5, thereby improving the practicality of use.

[0029] Specifically, a fastening seat 411 is provided at one end of the square plug rod 42, a fastening plate 412 is provided inside the fastening seat 411, a fastening spring 413 is provided at the connection between the fastening seat 411 and the fastening plate 412, limiting sliders 414 are provided on both sides of the fastening plate 412, and the middle sliding connection of the limiting slider 414 is connected to a limiting slide rod 415.

[0030] By adopting the above technical solution, when the blocking block 5 blocks the test tube, it will drive the fastening plate 412 to move in the fastening seat 411 to compress the fastening spring 413, so that the blocking block 5 has a good effect of blocking the test tube.

[0031] Specifically, a guide sliding opening is provided at one end of the clamping block 43 , and a clamping hole matching the clamping block 43 is provided at one side of the square plug rod 42 .

[0032] By adopting the above technical solution, the guide slide makes it easy for the square plug rod 42 to abut against the clamping block 43 when it is installed, and can drive the clamping block 43 to move to one side. The clamping hole facilitates the insertion of the clamping block 43 to fix the square plug rod 42.

[0033] Specifically, one end of the clamping slider 45 is slidably connected to a stabilizing slider, and a bearing is provided at the connection between the square insert rod 42 and the fastening seat 411 .

[0034] By adopting the above technical solution, the stabilizing slide bar facilitates the stable sliding of the clamping slider 45 , and the bearing facilitates the rotation between the fastening seat 411 and the square insert rod 42 .

[0035] When this embodiment is in use: pull the pull rod 44, the pull rod 44 drives the clamping slider 45 to move and compress the clamping spring 46, so that the clamping block 43 disengages from the clamping hole, so that the square plug rod 42 and the disassembly seat 41 can be separated, so that the blocking block 5 is removed and cleaned. When the blocking block 5 blocks the test tube, it will drive the fastening plate 412 to move in the fastening seat 411 to compress the fastening spring 413, so that the blocking block 5 has a good effect of blocking the test tube, so that when the device is in use, it is convenient to disassemble and assemble the blocking block 5, and clean the blocking block 5, thereby improving the practicality of use.

[0036] Example 2

[0037] The present embodiment is different from the embodiment 1 in that: specifically, the connecting assembly 9 includes a connecting seat 91, a rotating rod 92, a bevel gear 1 93, a bevel gear 2 94 and a turning handle 95, wherein a connecting seat 91 is provided on one side of the clamping seat 7, a rotating rod 92 is provided inside the connecting seat 91, a turning handle 95 is provided at one end of the rotating rod 92, a bevel gear 1 93 is provided above the rotating rod 92, and a bevel gear 2 94 is meshedly connected to one side of the bevel gear 1 93.

[0038] By adopting the above technical solution, the handle 95 is rotated, the handle 95 drives the rotating rod 92 to rotate, the rotating rod 92 drives the bevel gear 1 93 to rotate, the bevel gear 1 93 drives the bevel gear 2 94 to rotate, the bevel gear 2 94 drives the bidirectional threaded screw 8 to rotate, so that the clamping frame 10 moves to clamp the test tube. When the device is in use, it can drive the two bidirectional threaded screws 8 to rotate at the same time, thereby driving the clamping frame 10 to move and clamp the test tube, thereby improving the practicality of use.

[0039] Specifically, a support rod 96 is disposed on the surface of the turning handle 95, and the support rod 96 is disposed in a surrounding manner.

[0040] By adopting the above technical solution and the arrangement of the support rod 96 , it is convenient to rotate the handle 95 .

[0041] Specifically, the rotating rod 92 and the connecting seat 91 are rotatably connected via a bearing, and one end of the bidirectional threaded screw 8 and the connecting seat 91 are also rotatably connected via a bearing.

[0042] By adopting the above technical solution, the rotating rod 92 and the connecting seat 91 can be rotated, and the bidirectional threaded screw 8 and the connecting seat 91 can also be rotated.

[0043] When this embodiment is in use: the turning handle 95 is rotated, the turning handle 95 drives the turning rod 92 to rotate, the rotation of the turning rod 92 drives the bevel gear 1 93 to rotate, the rotation of the bevel gear 1 93 drives the bevel gear 2 94 to rotate, the rotation of the bevel gear 2 94 drives the bidirectional threaded screw 8 to rotate, thereby moving the clamping frame 10 to clamp the test tube, so that when the device is in use, it can drive the two bidirectional threaded screws 8 to rotate at the same time, thereby driving the clamping frame 10 to move and clamp the test tube, thereby improving the practicality of use.

[0044] The structure and use principle of the centrifuge body 1 and the stabilizing mechanism 2 in the utility model have been disclosed in an immune cell centrifuge disclosed in Chinese patent application No. 202221189132.X. Its working principle is to put the test tube in, clamp the test tube by the clamping frame 10, and then close the cover 3 to perform centrifugal work. When the centrifuge rotates at high speed, the whole device shakes greatly. The anti-slip base is used to stabilize the device. The stabilizing mechanism 2 is made of soft rubber material and has a certain shock-absorbing effect. The centrifuge is supported by a support column, and finally the separated immune cells are taken out of the centrifuge for preservation.

[0045] The working principle and use process of the utility model: when the utility model is used, the test tube is put in, and the two bidirectional threaded screws 8 are driven to rotate simultaneously through the connecting component 9, thereby driving the clamping frame 10 to move, clamping and fixing the test tube, and then closing the cover 3, sealing the test tube through the blocking block 5, and then the work can be carried out, and finally the separated immune cells are taken out from the centrifugal device for storage, and then the blocking block 5 can be removed and cleaned through the convenient disassembly and assembly component 4. When the convenient disassembly and assembly component 4 is in use, the pull rod 44 is pulled, and the pull rod 44 drives the clamping slider 45 to move and compress the clamping spring 46, so that the clamping block 43 is disengaged from the clamping hole, so that the square plug rod 42 and the disassembly and assembly seat 41 can be separated, thereby removing the blocking block 5, cleaning the blocking block 5, and sealing the test tube with the blocking block 5 When blocking, it will drive the fastening plate 412 to move and compress the fastening spring 413 in the fastening seat 411, so that the sealing block 5 has a good effect of sealing the test tube, so that when the device is in use, it is convenient to disassemble and assemble the sealing block 5, and clean the sealing block 5, thereby improving the practicability of use. When the connecting component 9 is in use, the turning handle 95 is rotated, and the turning handle 95 drives the rotating rod 92 to rotate, and the rotation of the rotating rod 92 drives the bevel gear 1 93 to rotate, and the rotation of the bevel gear 1 93 drives the bevel gear 2 94 to rotate, and the rotation of the bevel gear 2 94 drives the bidirectional threaded screw 8 to rotate, thereby making the clamping frame 10 move to clamp the test tube, so that when the device is in use, it can drive the two bidirectional threaded screws 8 to rotate at the same time, thereby driving the clamping frame 10 to move and clamp the test tube, thereby improving the practicability of use.

[0046] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An immune cell centrifugal device, comprising a centrifugal device body, characterized in that: A stabilizing mechanism is arranged below the centrifugal device body, a cover plate is arranged above the centrifugal device body, a convenient disassembly and assembly component is arranged in the middle of the cover plate, a blocking block is arranged below the convenient disassembly and assembly component, a centrifugal seat is arranged inside the centrifugal device body, a clamping seat is arranged inside the centrifugal seat, two sides of the clamping seat are arranged inside, a connecting assembly is arranged at one end of the two-way threaded screw rod, and the surface of the two-way threaded screw rod is symmetrical and is threadedly connected to the clamping frame.

2. The immune cell centrifuge device according to claim 1, characterized in that: The convenient disassembly and assembly component includes a disassembly and assembly seat, a square plug rod, a clamping block, a pull rod, a clamping slide block and a clamping spring, wherein a disassembly and assembly seat is arranged in the middle of the cover plate, a square plug rod is inserted below the disassembly and assembly seat, a clamping block is arranged on one side of the square plug rod, a pull rod is arranged at one end of the clamping block, a clamping slide block is arranged above the pull rod, and a clamping spring is arranged on one side of the clamping slide block.

3. An immune cell centrifugal device according to claim 2, characterized in that: A fastening seat is arranged at one end of the square plug rod, a fastening plate is arranged inside the fastening seat, a fastening spring is arranged at the connection between the fastening seat and the fastening plate, limiting sliders are arranged on both sides of the fastening plate, and the middle sliding connection of the limiting slider is connected to the limiting slide rod.

4. The immune cell centrifugal device according to claim 2, characterized in that: A guide sliding opening is provided at one end of the clamping block, and a clamping hole matching the clamping block is provided at one side of the square plug rod.

5. The immune cell centrifugal device according to claim 3, characterized in that: One end of the clamping slide block is slidably connected with a stabilizing slide bar, and a bearing is arranged at the connection between the square insert rod and the fastening seat.

6. The immune cell centrifugal device according to claim 1, characterized in that: The connecting assembly includes a connecting seat, a rotating rod, a bevel gear 1, a bevel gear 2 and a turning handle, wherein a connecting seat is provided on one side of the clamping seat, a rotating rod is provided inside the connecting seat, a turning handle is provided at one end of the rotating rod, a bevel gear 1 is provided above the rotating rod, and one side of the bevel gear 1 is meshedly connected with the bevel gear 2.

7. The immune cell centrifugal device according to claim 6, characterized in that: A support rod is arranged on the surface of the turning handle, and the support rod is arranged in a surrounding manner.

8. The immune cell centrifugal device according to claim 6, characterized in that: The rotating rod and the connecting seat are rotatably connected via a bearing, and one end of the bidirectional threaded screw and the connecting seat are also rotatably connected via a bearing.

Citation Information

Patent Citations

  • Immune cell centrifugal device

    CN217221946U