Intelligent equipment for extracting sulforaphane from broccoli seeds

Abstract

The utility model provides intelligent equipment for extracting sulforaphane from broccoli seeds. The intelligent equipment comprises a pretreatment stirring kettle, the sedimentation centrifuge is connected with the pretreatment stirring kettle; the first buffer tank is connected with the sedimentation centrifuge; the defoamer is connected with the first buffer tank; the extraction tank is connected with the defoamer; the resin chromatographic column is connected with the extraction tank; and the spherical concentrator is connected with the resin chromatographic column and is used for increasing the concentration of sulforaphane. Through arrangement of a pretreatment stirring kettle, a sedimentation centrifuge, a first buffer tank, a defoamer, an extraction tank, a resin chromatographic column and a spherical concentrator, and a control assembly connected with the equipment, cooperative work of the equipment is realized, and through a preset operation instruction, the intelligent equipment can automatically execute the extraction process, so that the extraction efficiency and scale are improved, and the production cost is reduced. The industrial extraction scale of the sulforaphane is expanded, the production capacity is improved, and meanwhile, the possibility of misoperation generated in the manual extraction process is also avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of plant active ingredient extraction equipment, in particular to an intelligent device for extracting sulforaphane from broccoli seeds. Background Technique

[0002] Sulforaphane, also known as "raphanin" (1-isothiocyanato-4-methylsulfonylbutane) (Sulforaphane), is relatively rich in cruciferous plants such as broccoli, kale, and northern round red radishes. It is a common antioxidant and the plant active substance with the best anti-cancer effect found in vegetables. Its molecular formula is: C6H11S2NO. It is the most potent and effective active ingredient among all natural anti-cancer substances discovered as of 2012, and it has unique anti-cancer effects. It can cause apoptosis and cell arrest of cancer cells, and at the same time can induce phase II detoxifying enzymes in the human body while inhibiting the production of type I enzymes. Eventually, harmful components such as carcinogens and free radicals are excreted through multiple enzyme systems. At the same time, this component will not remain in the human body and has no side effects on the body. It is a new type of anti-cancer component. The United States has been researching the substance of sulforaphane and its production methods since the 1950s.

[0003] Currently, patent documents regarding the extraction and preparation of sulforaphane, such as: CN101514174B, disclose a method for extracting multifunctional sulforaphane from broccoli sprout seedlings, which proposes to achieve high-efficiency extraction and high-purity acquisition of sulforaphane by optimizing extraction conditions and process flows. However, this method needs to consider the growth time of sprout seedlings, and all pre-treatments of sprout seedlings are manually controlled, resulting in production only in the laboratory, which limits the production capacity.

[0004] Another example is the patent document: CN101229211A, which discloses an extract of broccoli seeds and its preparation method. Although the method mentioned is applicable to the preparation of broccoli seed extracts, it does not provide an idea for production equipment on how to maintain extraction efficiency and product quality in large-scale production. It still cannot solve the problem of high difficulty in industrial production. This traditional extraction method is feasible on a laboratory scale but faces challenges in large-scale production, and it cannot guarantee issues such as equipment scale-up, continuity of the extraction process, and consistency of product quality during large-scale production. Content of the Utility Model

[0005] [[ID=ID=19]]Aiming at the deficiencies of the existing technology, the purpose of the utility model is to provide an intelligent device for extracting sulforaphane from broccoli seeds, so as to solve the problems raised in the above background technology. By cooperating with a series of equipment for extracting sulforaphane, after setting the execution instructions in advance, the defects of low automation control level and inability to produce on a large scale caused by manually adjusting the speed of the frequency converter are avoided. The problems in the existing technology are solved.

[0006] To achieve the above object, the present utility model is realized through the following technical solutions: To achieve the above object, the present utility model is realized through the following technical solutions: An intelligent device for extracting sulforaphane from broccoli seeds, comprising a pretreatment stirring kettle for fully stirring broccoli seed powder; a sedimentation centrifuge connected to the pretreatment stirring kettle for realizing solid-liquid separation of the seed powder; a first buffer tank connected to the sedimentation centrifuge for receiving and temporarily storing the separated material; an antifoamer connected to the first buffer tank for removing bubbles in the material; an extraction tank connected to the antifoamer for extracting the defoamed material; a resin chromatography column connected to the extraction tank for further purifying the target compound sulforaphane; a spherical concentrator connected to the resin chromatography column for concentrating the processed material to increase the concentration of sulforaphane.

[0007] Compared with the prior art, the beneficial effects of the present utility model are:

[0008] To solve the drawback that the prior art can only extract sulforaphane in the laboratory, the present utility model sets key devices such as a pretreatment stirring kettle, a sedimentation centrifuge, a first buffer tank, an antifoamer, an extraction tank, a resin chromatography column, and a spherical concentrator, and realizes the coordinated work between the devices through the connected control components. Based on the preset operation instructions, the intelligent device can automatically execute the extraction process, thereby improving the extraction efficiency and scale, expanding the industrial extraction scale of sulforaphane, enhancing the production capacity, and at the same time, also avoiding the possibility of misoperation in the manual extraction process. BRIEF DESCRIPTION OF THE DRAWINGS

[0009] The disclosure of the present utility model will be described with reference to the accompanying drawings. It should be understood that the drawings are only for illustrative purposes and are not intended to limit the protection scope of the present utility model. In the drawings, the same reference numerals are used to refer to the same components. Among them:

[0010] Figure 1 is a process flow diagram of extracting sulforaphane from broccoli seeds proposed in an embodiment of the present utility model;

[0011] Figure 2 is a schematic diagram of the equipment layout structure for extracting sulforaphane from broccoli seeds proposed in an embodiment of the present utility model.

[0012] Reference numerals:

[0013] 1 - Pretreatment stirring tank, 2 - Settling centrifuge, 3 - First buffer tank, 31 - Defoamer, 4 - Tubular centrifuge, 5 - Second buffer tank, 6 - Extraction tank, 7 - Resin chromatography column, 8 - Third buffer tank, 9 - Eluent storage tank, 10 - Spherical concentrator, 11 - Fourth buffer tank, 111 - Hydrocyclone, 112 - Plate and frame heat exchanger, 12 - Alcohol modulation tank, 13 - New alcohol tank, 14 - Air compressor supply unit, 15 - Air-cooled unit, 16 - Electric boiler supply unit, A - First valve island, B - Second valve island, C - F1 flowmeter, D - F2 flowmeter. Detailed implementation manners

[0014] It is easily understood that according to the technical solution of the present invention, without changing the essence of the present invention, those of ordinary skill in the art can propose various structural ways and implementation ways that can be mutually replaced. Therefore, the following detailed implementation manners and the accompanying drawings are only exemplary descriptions of the technical solution of the present invention, and should not be regarded as the whole of the present invention or as a limitation or restriction on the technical solution of the present invention.

[0015] As Figure 1 - Figure 2 shown, as an embodiment of the present invention, a technical solution is provided: An intelligent device for extracting sulforaphane from broccoli seeds, comprising:

[0016] A pretreatment stirring tank 1 for fully stirring the broccoli seed powder to prepare for the extraction process; a settling centrifuge 2 connected to the pretreatment stirring tank 1 for realizing the solid-liquid separation of the seed powder; a first buffer tank 3 connected to the settling centrifuge 2 for receiving and temporarily storing the separated liquid material; a defoamer 31 connected to the first buffer tank 3 for removing the bubbles in the liquid material to improve the subsequent processing efficiency; an extraction tank 6 connected to the defoamer 31 for extracting the liquid material after defoaming; a resin chromatography column 7 connected to the extraction tank 6 for further purifying the target compound sulforaphane; a spherical concentrator 10 connected to the resin chromatography column 7 for concentrating the processed material to increase the concentration of sulforaphane.

[0017] In one embodiment of the present invention, to address the drawbacks of existing technologies that sulforaphane can only be extracted in the laboratory and to avoid the problem that the existing technologies all rely on manual extraction, which limits production capacity, a control component is proposed to set the initial parameters of each component to achieve an automated process for extracting sulforaphane from broccoli seeds. It should be noted that the proposed control component includes: an intelligent explosion-proof control unit, a touch screen explosion-proof control panel, a first valve island, a second valve island, an F1 flowmeter, an F2 flowmeter, and a plurality of valves that exchange data and transmit commands with the intelligent explosion-proof control unit via a communication protocol. The intelligent explosion-proof control unit is installed at the central control position of the entire intelligent device and is electrically connected to each device in the intelligent device. It receives commands from the touch screen explosion-proof control panel via a communication protocol and executes corresponding safety control measures based on the commands. The first valve island and the second valve island are respectively installed at nodes of the fluid delivery pipeline of the entire intelligent device to control the flow direction and flow rate of the fluid. The F1 flowmeter and the F2 flowmeter are respectively installed on the fluid delivery pipeline to measure the flow rate of a specific pipeline section. Each valve is installed at a fluid delivery pipeline section to control the flow direction and flow rate of the fluid.

[0018] Based on the above technical concept, during specific implementation, the intelligent explosion-proof control unit is built into the intelligent explosion-proof cabinet and is electrically connected to the pretreatment stirring tank 1, sedimentation centrifuge 2, first buffer tank 3, defoamer 31, tubular centrifuge 4, second buffer tank 5, extraction tank 6, resin chromatography column 7, third buffer tank 8, eluent storage tank 9, spherical concentrator 10, fourth buffer tank 11, cyclone 111, plate and frame heat exchanger 112, alcohol preparation tank 12, new alcohol tank 13, air compressor air supply unit 14, air cooling unit 15, electric boiler air supply unit 16, first valve island A, second valve island B, F1 flowmeter C, F2 flowmeter D, and multiple valves. It receives instructions from the touch screen explosion-proof control panel through a communication protocol and executes corresponding safety control measures according to the instructions. The touch screen explosion-proof control unit is built into the touch screen explosion-proof box and installed in a location convenient for operators to access. It is connected to the intelligent explosion-proof control unit via a communication line and is used for the operation interface and control of the explosion-proof equipment.

[0019] As an embodiment of the present utility model, the intelligent device also includes a material storage and processing component, which includes a second buffer tank 5, which is connected to the tubular centrifuge 5 in sequence and then connected to the pipeline connecting the extraction tank 6 and the defoamer 31, for storing materials processed by the tubular centrifuge 4; a third buffer tank 8, which is connected to the resin chromatography column 7, for storing materials processed by the resin chromatography column; an eluent storage tank 9, which is connected to the third buffer tank 8 through a pipeline and then connected to the spherical concentrator 10 to store the eluent used for resin chromatography.

[0020] The intelligent device further includes a temperature regulation component, which includes a plate-frame heat exchanger 112 connected to the spherical concentrator 10 for regulating the temperature of the material; and an air-cooled unit 15 connected to the plate-frame heat exchanger 112 for cooling the material.

[0021] As an embodiment of the present utility model, the intelligent device further includes an alcohol modulation and storage component and a gas supply component disposed outside the intelligent device. Specifically, the gas supply component includes an air compressor gas supply unit 14 that provides compressed air through a pipeline to support the pneumatic operation of the device; and an electric boiler gas supply unit 16 that provides steam through a pipeline to support the heating process of the spherical concentrator 10. The alcohol modulation and storage component includes a fourth buffer tank 11 connected to the spherical concentrator 10 for storing the output material after the chromatography process; an alcohol modulation tank 12 connected to the plate-frame heat exchanger 112 for modulating the alcohol solution for chromatography; and a new alcohol tank 13 connected to the alcohol modulation tank 12 for storing the modulated alcohol solution. It can be understood that the alcohol solution in the new alcohol tank 13 is used as an eluent during the chromatography process, and the output material after chromatography is transported to the fourth buffer tank 11.

[0022] As an embodiment of the present utility model, the intelligent device further includes a hydrocyclone 111 installed in the buffer tank 11 for separating the output material from the spherical concentrator 10. Specifically, the hydrocyclone 111 separates the solid particles and liquid in the material through the centrifugal force generated by high-speed rotation, and the solid particles and liquid are discharged through the bottom and top outlets of the hydrocyclone 111 respectively, achieving effective separation.

[0023] In an embodiment of the present utility model, for fine control, to ensure the balance of the material quantity, and at the same time achieve power saving and energy saving control, the intelligent device also proposes to install a motor on the drive shaft of the pretreatment stirring kettle 1 as the power source of the pretreatment stirring kettle 1 to provide the necessary power to achieve sufficient stirring of the seed powder. At the same time, pump motors are installed at the pipeline connecting the sedimentation centrifuge 2 and the first buffer tank 3, at the pipeline connecting the second buffer tank 5 and the extraction tank 6, and at the material conveying pipeline at the connection of the resin chromatography column 7 and the spherical concentrator 10, respectively, for the purpose of transporting the material or the concentrated sulforaphane from one place to another. At the same time, a tubular centrifugal motor is installed in the drive system of the tubular centrifuge 4 to provide the required rotational power for the centrifugation process. Finally, to facilitate real-time provision of liquid level data, a liquid level gauge L1 is installed in the second buffer tank 5 or the extraction tank 6 container to monitor the liquid level height, so as to adjust the running speed of the pump according to the liquid level change.

[0024] Based on the above technical concept, it should be noted that the proposed motor, pump motor, tubular centrifugal motor, and liquid level gauge L1 are all connected to the intelligent explosion-proof control unit.

[0025] The principle of extracting sulforaphane from broccoli seeds proposed by this utility model is as follows:

[0026] First, the broccoli seed powder in the pretreatment stirring tank 1 is fully mixed by a stirrer driven by a motor to prepare for extraction. Then, the sedimentation centrifuge 2 separates the mixture into solid and liquid phases. The liquid part flows into the first buffer tank 3, where it is temporarily stored and the bubbles are removed by the defoamer 31. Next, the defoamed liquid in the extraction tank 6 undergoes an extraction process to obtain a solution rich in sulforaphane, which is then further purified in the resin chromatography column 7. The purified solution is concentrated in the spherical concentrator 10 to increase the concentration of sulforaphane.

[0027] During this process, the plate-frame heat exchanger 112 and the air-cooled unit 15 work together under the control of the intelligent explosion-proof control unit according to preset instructions to adjust the temperature of the material and ensure the optimal extraction conditions. The alcohol modulation tank 12 modulates the alcohol solution, and the new alcohol tank 13 stores the modulated solution to provide the necessary pneumatic operation and heating processes for the air compressor supply unit 14 and the electric boiler supply unit 16. The second buffer tank 5 and the third buffer tank 8 store the processed material and the material after the resin chromatography column respectively, and the eluent storage tank 9 stores the eluent.

[0028] The intelligent explosion-proof control unit and the touch-screen explosion-proof control panel cooperate to control the safe operation of the whole production. Through the connection with the first valve island, the second valve island, the F1 flowmeter, the F2 flowmeter and multiple valves, precise fluid control is achieved. Finally, the output material of the spherical concentrator 10 is separated in the fourth buffer tank 11 by the set hydrocyclone 111 to complete the whole extraction process and realize the large-scale production of high-purity sulforaphane from broccoli seeds.

[0029] The technical scope of this utility model is not limited to the content described above. Those skilled in the art can make various deformations and modifications to the above embodiments without departing from the technical idea of this utility model, and these deformations and modifications shall all fall within the protection scope of this utility model.

Claims

1. An intelligent device for extracting sulforaphane from broccoli seeds, characterized in that, including a pretreatment stirring kettle (1) for fully stirring the broccoli seed powder; a sedimentation centrifuge (2) connected to the pretreatment stirring kettle (1) for realizing the solid-liquid separation of the seed powder; a first buffer tank (3) connected to the sedimentation centrifuge (2) for receiving and temporarily storing the separated materials; an antifoamer (31) connected to the first buffer tank (3) for removing the bubbles in the materials; an extraction tank (6) connected to the antifoamer (31) for extracting the materials after defoaming treatment; a resin chromatography column (7) connected to the extraction tank (6) for further purifying the target compound sulforaphane; a spherical concentrator (10) connected to the resin chromatography column (7) for concentrating the treated materials and increasing the concentration of sulforaphane.

2. The intelligent device for extracting sulforaphane from broccoli seeds according to claim 1, wherein It further includes a control component, and the control component includes: an intelligent explosion-proof control unit and a touch screen explosion-proof control panel. Among them, the intelligent explosion-proof control unit is installed at the central control position of the entire intelligent device, receives instructions from the touch screen explosion-proof control panel through a communication protocol, and executes corresponding safety control measures according to the instructions.

3. The intelligent device for extracting sulforaphane from broccoli seeds according to claim 2, wherein The control component further includes: a first valve island, a second valve island, an F1 flowmeter, an F2 flowmeter and a plurality of valves that perform data exchange and instruction transmission with the intelligent explosion-proof control unit through a communication protocol. Among them, the first valve island and the second valve island are respectively installed at the nodes of the fluid conveying pipeline of the entire intelligent device for controlling the fluid flow direction and flow rate; the F1 flowmeter and the F2 flowmeter are respectively installed on the fluid conveying pipeline for measuring the flow rate of a specific pipeline section; each of the valves is respectively installed at the fluid conveying pipeline section for controlling the fluid flow direction and flow rate.

4. The intelligent device for extracting sulforaphane from broccoli seeds according to claim 1, characterized in that, It further includes a material storage and processing component. Among them, the material storage and processing component includes: a second buffer tank (5) connected to a tubular centrifuge (4) in sequence and then connected to the pipeline where the extraction tank (6) is connected to the antifoamer (31); a third buffer tank (8) connected to the resin chromatography column (7) for storing the materials processed by the resin chromatography column; an eluent storage tank (9) connected to the third buffer tank (8) through a pipeline and then connected to the spherical concentrator (10) to store the eluent for resin chromatography.

5. The intelligent device for extracting sulforaphane from broccoli seeds according to claim 1, wherein It further includes a temperature regulation component. Among them, the temperature regulation component includes: a plate-frame heat exchanger (112) connected to the spherical concentrator (10) for regulating the temperature of the materials; an air-cooled unit (15) connected to the plate-frame heat exchanger (112) for cooling the materials.

6. The intelligent device for extracting sulforaphane from broccoli seeds according to claim 1, characterized in that, ​ ​ ​ 7. An intelligent device for extracting sulforaphane from broccoli seeds according to claim 1, characterized in that, ​ ​ ​ A new alcohol tank (13), which is connected to the alcohol modulation tank (12) and is used for storing the modulated alcohol solution.

8. An intelligent device for extracting sulforaphane from broccoli seeds according to claim 7, characterized in that, It further includes a hydrocyclone (111), wherein, the hydrocyclone (111) is installed in the buffer tank (11) and is used for separating the output material from the spherical concentrator (10).

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