Metering and subpackaging device

Abstract

The utility model discloses a metering and subpackaging device which comprises a cover plate, a material storage component, a metering plate and a subpackaging plate. A plurality of material storage holes are formed in the material storage component, a plurality of metering holes are formed in the metering plate, and a plurality of sub-packaging holes are formed in the sub-packaging plate; the cover plate, the material storage component and the split charging plate are sequentially connected, the metering plate is arranged between the material storage component and the split charging plate in a sliding mode, and the metering holes are aligned with the material storage holes or the split charging holes through relative position changes of the metering plate. The metering and subpackaging device provided by the utility model can carry out quantitative subpackaging for multiple times, multiple equivalent substances can be obtained through each quantitative subpackaging operation, the weight error between subpackaged substances is small, and the error range can be used in a high-throughput chemical experiment.

Description

Technical Field

[0001] The utility model relates to the technical field of chemical experiment equipment, in particular to a metering and dispensing device. Background Art

[0002] In the process of high-throughput chemical experiments, it is necessary to load drug powders or bright beads into each reaction bottle of a porous reaction plate. Usually, the method is to manually weigh a single drug powder or bright bead and then load it into a single reaction bottle, which is time-consuming and laborious.

[0003] Patent CN201710546229.9 discloses a device for equally dispensing trace (mg-level) solid powders, which can dispense multiple equal amounts of solid powders at one time, greatly solving the efficiency problem of manual dispensing. However, after loading solid powders once, the above device can only be dispensed once. To perform the second dispensing, it is necessary to refill. And because the solid powder particles are small, when using the above device for dispensing, the powder is very easy to enter between the metering plate and the powder leakage plate, causing cross-contamination and affecting the accuracy of the experimental results.

[0004] In summary, there is an urgent need for a metering and dispensing device to solve the problems existing in the related technologies. Summary of the Utility Model

[0005] In view of the above problems, the utility model discloses a metering and dispensing device, which includes a cover plate, a storage component, a metering plate and a dispensing plate; the storage component is provided with a plurality of storage holes, the metering plate is provided with a plurality of metering holes, and the dispensing plate is provided with a plurality of dispensing holes;

[0006] The cover plate, the storage component and the dispensing plate are sequentially connected, and the metering plate is slidably arranged between the storage component and the dispensing plate. By changing the relative position of the metering plate, the metering holes are aligned with the storage holes or the metering holes are aligned with the dispensing holes.

[0007] Preferably, the storage component includes a storage plate A and a storage plate B arranged in sequence. A cover plate is arranged on the side of the storage plate A away from the storage plate B, and a dispensing plate is arranged on the side of the storage plate B away from the storage plate A. The metering plate is slidably arranged between the storage plate B and the dispensing plate; the storage holes include storage holes A and storage holes B. A plurality of storage holes A are arranged on the storage plate A, and a plurality of storage holes B are arranged on the storage plate B; the storage holes A and the storage holes B are arranged in one-to-one correspondence.

[0008] Preferably, the storage hole B is a tapered hole. The large-diameter section of the storage hole B is close to the side of the storage plate A and the aperture is greater than or equal to that of the storage hole A. The small-diameter end of the storage hole B is away from the side of the storage plate A and the aperture is less than or equal to that of the metering hole.

[0009] Preferably, it further includes a plurality of positioning blocks arranged on the storage component and a plurality of positioning grooves arranged on the metering plate. The positioning blocks cooperate with the positioning grooves to fix the position of the metering plate relative to the storage component when the metering holes are aligned with the storage holes B or the metering holes are aligned with the dispensing holes.

[0010] Preferably, a handle is further arranged on the metering plate.

[0011] Preferably, the dispensing plate is clamped with the storage plate B, the storage plate A is clamped with the storage plate B, and the cover plate is clamped with the storage plate A.

[0012] Preferably, a sliding groove for accommodating the metering plate is arranged on the dispensing plate. The metering plate is slidably arranged in the sliding groove, and the upper surface of the metering plate is flush with the upper surface of the dispensing plate, and the lower surface is flush with the bottom of the sliding groove.

[0013] Preferably, a plurality of bosses corresponding to the storage holes A one by one are arranged on the cover plate.

[0014] Preferably, a groove is arranged along the circumferential direction of the hole on the side of the storage hole B close to the metering plate, and a rubber sleeve is arranged in the groove.

[0015] Preferably, a positioning structure is further arranged on the side of the dispensing plate away from the metering plate; the positioning structure includes a first card slot and a second card slot arranged along the circumferential direction of the dispensing hole;

[0016] The first card slot is used to position the reaction plate;

[0017] The second card slot is used to position the reaction bottles in the reaction plate.

[0018] Preferably, the dispensing plate, the storage plate B and the storage plate A are sequentially bolted in the reverse direction of material falling, and the storage plate A and the cover plate are bolted in the direction of material falling.

[0019] The beneficial effects of this application compared with the prior art are as follows:

[0020] (1) Through the technical solution of the present utility model, multiple quantitative dispensing can be carried out. Each quantitative dispensing operation can obtain multiple equal amounts of substances, and the weight error between each dispensed substance is small, and the error range can be used in high-throughput chemical experiments; and the aperture size and thickness of the metering holes in the metering plate can be customized according to experimental requirements, so as to control the weight of the substances in each metering hole during a single dispensing process.

[0021] (2) Through the technical solution of the present utility model, the storage component is divided into the storage plate A and the storage plate B. In this way, while ensuring the storage capacity of the storage component to the greatest extent, the difficulty of drilling processing is reduced, thereby reducing the processing cost of the storage component.

[0022] (3) Through the technical solution of the present utility model, by clamping between the sub-packaging plate and the storage plate B, and between the storage plate A and the storage plate B, the accurate docking between each component can be achieved. Moreover, the sub-packaging plate, the storage plate B, and the storage plate A are sequentially bolted along the reverse direction of the material falling. The storage plate A and the cover plate are bolted along the material falling direction. When a blockage occurs, the entire metering and sub-packaging device is inverted and the connecting bolts between the sub-packaging plate, the storage plate B, and the storage plate A along the reverse direction of the material falling are removed, so as to sequentially remove the sub-packaging plate, the metering plate, and the storage plate B to check the blockage part. At this time, through the function of the above clamping, when removing a certain component, other components will not slip due to the lack of screw fixation, resulting in the leakage of the stored substance (powder or bright beads).

[0023] (4) Through the technical solution of the present utility model, a groove is provided along the circumferential direction of the hole on the side of the storage hole close to the metering plate, and a rubber sleeve is arranged in the groove. By means of the rubber sleeve, the risk that the substance to be sub-packaged (such as powder or bright beads) enters between the storage plate B and the metering plate during material falling and sub-packaging can be avoided, and the situation of cross-contamination can be avoided.

[0024] In the following, the optimal embodiments of implementing the present application will be described in more detail with reference to the accompanying drawings, so as to easily understand the features and advantages of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the accompanying drawings required for the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0026] Figure 1 It is a schematic structural diagram of the metering and sub-packaging device in the embodiments of the present application;

[0027] Figure 2 For Figure 1 the exploded view of the metering and sub-packaging device in

[0028] Figure 3 For Figure 2 the schematic structural diagram of the metering plate of the metering and sub-packaging device in

[0029] Figure 4 For Figure 2 the schematic structural diagram of the sub-packaging plate of the metering and sub-packaging device in

[0030] Figure 5 For Figure 2 another perspective view of the sub-packaging plate of the metering and sub-packaging device in

[0031] Among them, 1 - cover plate; 2 - storage plate A; 3 - storage plate B; 4 - metering plate; 5 - sub-packaging plate; 6 - positioning block; 7 - positioning groove; 8 - handle; 9 - sliding groove; 10 - first card slot; 11 - second card slot. Detailed implementation mode

[0032] It should be noted that, without conflict, the embodiments in this application and the features in the embodiments can be combined with each other. The following further describes this application in detail with reference to the drawings and specific embodiments.

[0033] In the embodiments of this application, if there are directional indications such as up, down, left, right, front, back... they are only used to explain the relative positional relationship and movement conditions between components in a specific posture as shown in the drawings. If this specific posture changes, then the directional indications will also change accordingly.

[0034] In addition, in this application, the descriptions involving "first", "second", etc. are only for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one of these features.

[0035] For Embodiment 1, please refer to Figure 1 and Figure 2 , the embodiments of this application provide a metering and sub-packaging device, including a cover plate 1, a storage component, a metering plate 4, and a sub-packaging plate 5; the storage component is provided with 96 storage holes, the metering plate 4 is provided with 96 metering holes, and the sub-packaging plate 5 is provided with 96 sub-packaging holes;

[0036] The cover plate 1, the storage component, and the sub-packaging plate 5 are connected in sequence, and the metering plate 4 is slidably arranged between the storage component and the sub-packaging plate 5. By changing the relative position of the metering plate 4, the metering holes are aligned with the storage holes or the metering holes are aligned with the sub-packaging holes.

[0037] In this embodiment, the storage component includes a storage plate A 2 and a storage plate B 3 arranged in sequence. A cover plate 1 is arranged on the side of the storage plate A 2 away from the storage plate B 3, and a sub-packaging plate 5 is arranged on the side of the storage plate B 3 away from the storage plate A 2. The metering plate 4 is slidably arranged between the storage plate B 3 and the sub-packaging plate 5; the storage holes include storage holes A and storage holes B. The storage plate A 2 is provided with 96 storage holes A, and the storage plate B 3 is provided with 96 storage holes B; the storage holes A and the storage holes B are arranged in one-to-one correspondence.

[0038] In this embodiment, the storage hole B is a tapered hole. The large-diameter section of the storage hole B is close to the side of the storage plate A 2 and the aperture is equal to that of the storage hole A. The small-diameter end of the storage hole B is away from the side of the storage plate A 2 and the aperture is equal to that of the metering hole.

[0039] In this embodiment, referring to Figure 3 , it further includes two positioning blocks 6 (rotatably arranged, in this embodiment, the positioning blocks 6 are arranged on the storage plate A2) arranged on the storage component and two positioning slots 7 arranged on the metering plate 4. The positioning blocks 6 cooperate with the positioning slots 7 to fix the position of the metering plate 4 relative to the storage component when the metering holes are aligned with the storage holes B or the metering holes are aligned with the dispensing holes.

[0040] In this embodiment, referring to Figure 3 , a handle 8 is further arranged on the metering plate 4.

[0041] In this embodiment, the dispensing plate 5 is snap-connected with the storage plate B3, between the storage plate A2 and the storage plate B3, and between the cover plate 1 and the storage plate A2. Specifically, the two components are snap-connected through a boss-groove structure.

[0042] In this embodiment, referring to Figure 4 , a chute 9 for accommodating the metering plate 4 is arranged on the dispensing plate 5. The metering plate 4 is slidably arranged in the chute 9, and the upper surface of the metering plate 4 is flush with the upper surface of the dispensing plate 5, and the lower surface is flush with the bottom of the chute 9.

[0043] In this embodiment, a number of bosses corresponding to the storage holes A one by one are arranged on the cover plate 1 (for example, in this embodiment, there are 96 storage holes, so 96 bosses with sizes similar to those of the storage holes are correspondingly arranged on the cover plate 1. The material of the bosses can be selected from materials such as fluororubber, silica gel, and rubber that have good elastic deformation and are resistant to chemical corrosion).

[0044] In this embodiment, a groove is arranged along the circumferential direction of the storage hole B near the metering plate 4. The inner wall of the groove is partitioned, and a rubber sleeve is arranged in the groove; the material of the rubber sleeve includes materials such as fluororubber, silica gel, and rubber that have good elastic deformation and are resistant to chemical corrosion.

[0045] In this embodiment, referring to Figure 5 , a positioning structure is further arranged on the side of the dispensing plate 5 away from the metering plate 4; the positioning structure includes a first card slot 10 and a second card slot 11 arranged along the circumferential direction of the dispensing hole;

[0046] The first card slot 10 is used to position the reaction plate; a dispensing hole is arranged at the bottom of the first card slot 10.

[0047] The second card slot 11 is used to position the reaction bottles in the reaction plate, and the shape and size of the second card slot 11 match various multi-well plates that meet the SBS standard.

[0048] In this embodiment, the dispensing plate 5, the storage plate B3, and the storage plate A2 are sequentially bolted in the reverse direction of the material falling, and the storage plate A2 and the cover plate 1 are bolted in the material falling direction.

[0049] The process of applying the metering and dispensing device provided in this embodiment includes:

[0050] Assemble the storage plate A, the storage plate B, the metering plate, and the dispensing plate in sequence, move the metering plate to a suitable position so that the metering holes are aligned with the storage holes B, and position them through the positioning blocks and the positioning grooves. Add the powder to be dispensed into the storage hole A, and seal it with the cover plate; vibrate the metering and packaging device with a small hammer or other means so that the powder fills the entire metering hole. Then, place the reaction bottle in the 96-well reaction plate for dispensing and set it below the dispensing plate. Align the reaction bottle mouth with the dispensing hole through the positioning structure of the dispensing plate; move the metering plate so that the metering holes are aligned with the dispensing holes, and position them again through the positioning blocks and the positioning grooves. Vibrate the metering and packaging device with a small hammer or other means. At this time, the powder falls into the reaction bottle, and the dispensing process is completed.

[0051] The above further describes the present application with the aid of specific embodiments. However, it should be understood that the specific description here should not be construed as a limitation on the essence and scope of the present application. Various modifications made by those of ordinary skill in the art to the above embodiments after reading this specification all fall within the scope protected by the present application.

Claims

1. A metering and packaging device, characterized in that, It includes a cover plate (1), a material storage component, a metering plate (4), and a dispensing plate (5); the material storage component is provided with a number of material storage holes, the metering plate (4) is provided with a number of metering holes, and the dispensing plate (5) is provided with a number of dispensing holes; The cover plate (1), the material storage component, and the dispensing plate (5) are connected in sequence, and the metering plate (4) is slidably arranged between the material storage component and the dispensing plate (5), and the alignment of the metering holes with the material storage holes or the alignment of the metering holes with the dispensing holes is achieved through the change in the relative position of the metering plate (4).

2. The metering and filling device according to claim 1, wherein The material storage component includes a material storage plate A (2) and a material storage plate B (3) arranged in sequence. A cover plate (1) is arranged on the side of the material storage plate A (2) away from the material storage plate B (3), and a dispensing plate (5) is arranged on the side of the material storage plate B (3) away from the material storage plate A (2). The metering plate (4) is slidably arranged between the material storage plate B (3) and the dispensing plate (5); the material storage holes include material storage holes A and material storage holes B. A number of material storage holes A are arranged on the material storage plate A (2), and a number of material storage holes B are arranged on the material storage plate B (3); the material storage holes A and the material storage holes B are arranged in one-to-one correspondence.

3. The metering and dispensing device according to claim 2, wherein, The material storage hole B is a tapered hole. The large-diameter section of the material storage hole B is close to the side of the material storage plate A (2) and the hole diameter is greater than or equal to that of the material storage hole A. The small-diameter end of the material storage hole B is away from the side of the material storage plate A (2) and the hole diameter is less than or equal to that of the metering hole.

4. The metering and packaging device according to claim 2, characterized in that, It further includes a number of positioning blocks (6) arranged on the material storage component and a number of positioning grooves (7) arranged on the metering plate (4). The cooperation between the positioning blocks (6) and the positioning grooves (7) realizes the position fixation of the metering plate (4) relative to the material storage component when the metering holes are aligned with the material storage holes B or the metering holes are aligned with the dispensing holes.

5. The metering and dispensing device according to claim 2, characterized in that, The dispensing plate (5) is snap-connected with the material storage plate B (3), between the material storage plate A (2) and the material storage plate B (3), and between the cover plate (1) and the material storage plate A (2).

6. The metering and packaging device according to claim 1, wherein, The dispensing plate (5) is provided with a chute (9) for accommodating the metering plate (4). The metering plate (4) is slidably arranged in the chute (9), and the upper surface of the metering plate (4) is flush with the upper surface of the dispensing plate (5), and the lower surface is flush with the bottom of the chute (9).

7. The metering and packaging device according to claim 2, characterized in that, The cover plate (1) is provided with a number of bosses corresponding to the material storage holes A one by one.

8. The metering and packaging device according to claim 1, characterized in that, A groove is arranged along the circumferential direction of the material storage hole B on the side close to the metering plate (4), and a rubber sleeve is arranged in the groove.

9. The metering and packaging device according to claim 1, characterized in that, A positioning structure is further arranged on the side of the dispensing plate (5) away from the metering plate (4); the positioning structure includes a first card slot (10) and a second card slot (11) arranged along the circumferential direction of the dispensing hole; The first card slot (10) is used for positioning the position of the reaction plate; The second card slot (11) is used for positioning the position of the reaction vial in the reaction plate.

10. The metering and packaging device according to any one of claims 1-9, characterized in that, The dispensing plate (5), the material storage plate B (3), and the material storage plate A (2) are sequentially bolt-connected along the reverse direction of material falling, and the material storage plate A (2) and the cover plate (1) are bolt-connected along the material falling direction.

Images