Reaction device for continuously preparing structural lipid through pilot plant test enzyme catalysis

Abstract

The utility model discloses a reaction device for continuously preparing structural lipid through pilot plant test enzyme catalysis. The reaction device comprises a first reactor and a second reactor, a feeding hole of the first reactor is connected with a first feeding pipeline, and the other end of the first feeding pipeline is communicated with the loading pipeline; a feed port of the second reactor is connected with a second feed pipeline, and the other end of the second feed pipeline is communicated with the loading pipeline; a discharge port of the first reactor is connected with a first discharge pipeline, and a discharge port of the second reactor is connected with a second discharge pipeline; the first discharging pipeline is communicated with the first feeding pipeline through a first circulation pipeline, communicated with the second feeding pipeline through a second circulation pipeline and communicated with the discharging pipeline through a third circulation pipeline, and the third circulation pipeline is communicated with the first circulation pipeline through a branch pipeline. And the second discharging pipeline is communicated with the second feeding pipeline through a fourth circulating pipeline and is communicated with the blanking pipeline through a fifth circulating pipeline.

Description

Technical Field

[0001] This invention relates to the field of enzyme catalytic reactors. More specifically, it relates to a reaction apparatus for the pilot-scale continuous enzyme-catalyzed preparation of structured lipids. Background Technology

[0002] Currently, most enzyme catalytic reactors adopt a bottom-in, top-out feeding method. This method, where the material is affected by gravitational potential energy, places high demands on the feed pump. Enzyme feeding and discharging methods use fixed beds or stirred tanks as containers, typically adding enzymes from the top and removing them from the bottom. This is extremely inconvenient when adding or removing enzymes, and mechanical stirring can also reduce enzyme activity, thus increasing enzyme usage and production costs. Utility Model Content

[0003] In view of the above problems, one object of this utility model is to provide a reaction device for pilot-scale enzyme-catalyzed continuous preparation of structured lipids to improve enzyme utilization.

[0004] To achieve the above objectives, the present invention adopts the following technical solution:

[0005] A reaction apparatus for pilot-scale enzyme-catalyzed continuous preparation of structured lipids, comprising:

[0006] Raw material tank, first reactor, second reactor, and finished product tank;

[0007] The feed inlets of both the raw material tank and the finished product tank are located at the top, and the discharge outlets are located at the bottom.

[0008] The first reactor and the second reactor have the same structure, with the feed inlet located at the top and the discharge outlet located on the side;

[0009] The discharge port of the raw material tank is connected to the inlet of the first reactor and the inlet of the second reactor via a feeding pipeline, and the inlet of the finished product tank is connected to the discharge port of the first reactor and the outlet of the second reactor via a discharging pipeline.

[0010] The feed inlet of the first reactor is connected to a first feed pipe, and the other end of the first feed pipe is connected to the feeding pipe.

[0011] The feed inlet of the second reactor is connected to a second feed pipe, and the other end of the second feed pipe is connected to the feed pipe.

[0012] The discharge port of the first reactor is connected to a first discharge pipe, and the discharge port of the second reactor is connected to a second discharge pipe. Both the first discharge pipe and the second discharge pipe are arranged parallel to the horizontal plane.

[0013] The first discharge pipe is connected to the first feed pipe through the first circulation pipe, connected to the second feed pipe through the second circulation pipe, and connected to the discharge pipe through the third circulation pipe, and the third circulation pipe is connected to the first circulation pipe through a branch pipe;

[0014] The second discharge pipe is connected to the second feed pipe through the fourth circulation pipe, and to the discharge pipe through the fifth circulation pipe.

[0015] Alternatively, a two-position three-way valve may be installed between the third circulation pipeline and the branch pipeline to adjust the connection between the third circulation pipeline and the branch pipeline, and between the third circulation pipeline and the first discharge pipeline.

[0016] A three-position three-way valve is installed between the fifth circulation pipeline and the discharge pipeline to adjust the connection between the fifth circulation pipeline and the third circulation pipeline through the discharge pipeline, as well as the connection between the fifth circulation pipeline and the discharge pipeline.

[0017] Alternatively, one-way valves may be installed on the first feed pipe, the second feed pipe, the first circulation pipe, the second circulation pipe, and the fourth circulation pipe.

[0018] Alternatively, the reactor may include a tank with a top opening, a flange cover that is sealed to the top opening of the tank, and a polyester gasket and a filter screen that cover the top opening of the tank, with the filter screen located on the side of the polyester gasket facing away from the flange cover.

[0019] The polyester gasket includes several perforated holes that penetrate the upper and lower surfaces of the polyester gasket.

[0020] The reactor's inlet is located at the center of the flange cover, and the reactor's outlet is located on the side wall of the tank.

[0021] Alternatively, the reactor may also include an enzyme column installed inside the tank and a bent pipe located inside the tank and communicating with the bottom of the enzyme column.

[0022] The enzyme column includes a columnar carrier and an enzyme filled and fixed within the columnar carrier, and the bent tube is connected to the outlet of the columnar carrier.

[0023] The cylindrical carrier has an opening at the top and an outlet located at the bottom of the cylindrical carrier, which is a filter screen structure.

[0024] Alternatively, the bend may include a first section extending vertically to the outlet, a second section extending parallel to the horizontal plane from the bottom of the first section, a third section extending vertically upward from the end of the second section away from the first section, and a fourth section connecting the third section and the discharge port located on the side wall of the tank.

[0025] The length of the third segment is greater than the length of the first segment, and the fourth segment is set parallel to the horizontal plane.

[0026] Alternatively, the reaction apparatus may also include a hot water tank;

[0027] Both the first reactor and the second reactor are equipped with a circulating water bath. The inlet of the circulating water bath is located at the bottom edge of the corresponding first reactor and the corresponding second reactor, and the outlet of the circulating water bath is located at the upper edge of the corresponding first reactor and the corresponding second reactor.

[0028] The hot water tank is equipped with a circulating water pump at its outlet, and the inlets of the circulating water bath are all connected to the inlets of the hot water tank, while the outlets of the circulating water bath are all connected to the inlets of the hot water tank.

[0029] Alternatively, the reaction apparatus may further include a nitrogen system, which is connected to the first reactor, the second reactor, the raw material pipe, and the finished product tank via gas delivery pipes.

[0030] Alternatively, the raw material tank may be equipped with an automatic weighing device, a vacuum injection device, and a stirring device.

[0031] Alternatively, pressure drop caps can be installed in both the first and second reactors.

[0032] The beneficial effects of this utility model are as follows:

[0033] To address the technical problems existing in the prior art, this utility model provides a reaction device for the pilot-scale continuous enzyme-catalyzed preparation of structured lipids. By changing the feed and discharge methods of the reactor, the reaction device is made more suitable for industrial production. Equipping the reactor with a pressure drop cap and a bend in the tube can reduce the impact of materials on the enzyme and slow down the rate of enzyme activity decline. The use of a movable enzyme column improves the convenience and timeliness of enzyme loading and unloading, increases production efficiency, and makes it more suitable for large-scale production. By switching between internal and external circulation modes in the first and second reactors, and even more reactors, continuous preparation of structured lipids is achieved, enzyme recycling is enhanced, enzyme utilization is improved, and costs are effectively reduced. Attached Figure Description

[0034] The specific embodiments of this utility model will be further described in detail below with reference to the accompanying drawings.

[0035] Figure 1 A schematic diagram of the reaction apparatus provided in an embodiment of this utility model is shown.

[0036] Figure 2 A schematic diagram of the structure of the first reactor provided in an embodiment of the present invention is shown.

[0037] Figure 3 This diagram illustrates the structure of the enzyme column and the bent tube connection provided in an embodiment of the present invention.

[0038] Figure 4 This diagram illustrates the internal circulation working mode of the reaction device provided in this embodiment of the present invention.

[0039] Figure 5 This diagram illustrates the external cycle operation mode of the reaction device provided in this embodiment of the present invention.

[0040] Figure 6 This diagram illustrates the simultaneous feeding of the first reactor and the second reactor provided in an embodiment of the present invention. Detailed Implementation

[0041] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present invention and not intended to limit it. Furthermore, it should be noted that, for ease of description, the accompanying drawings show only the parts relevant to the present invention, not the entire structure.

[0042] In the description of this utility model, unless otherwise explicitly specified and limited, the terms "connected," "linked," and "fixed" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0043] In this invention, unless otherwise expressly specified and limited, the first feature being "above" or "below" the second feature may include direct contact between the first and second features, or contact between the first and second features not being in direct contact but through another feature between them.

[0044] In the description of this embodiment, the terms "upper," "lower," "left," and "right," etc., refer to the orientation or positional relationship shown in the accompanying drawings. They are used only for ease of description and simplification of operation, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In addition, the terms "first" and "second" are only used for distinction in description and have no special meaning.

[0045] To address the shortcomings of existing technologies, this invention provides a reaction apparatus for the pilot-scale continuous enzyme-catalyzed preparation of structured lipids, combined with... Figure 1-6 As shown, the reaction apparatus includes: a first reactor 1, a second reactor 2, a raw material tank 3, and a finished product tank 4.

[0046] The raw material tank 3 is used to load raw materials. The inlet 31 of the raw material tank 3 is located at the top of the raw material tank 3, and the outlet 32 ​​of the raw material tank 3 is located at the bottom of the raw material tank 3.

[0047] Finished product tank 4 is used to load finished products. The inlet 41 of finished product tank 4 is located at the top of finished product tank 4, and the outlet 42 of finished product tank 4 is located at the bottom of finished product tank 4.

[0048] The first reactor 1 and the second reactor 2 have the same structure. The feed inlet 11 of the first reactor 1 and the feed inlet 21 of the second reactor 2 are both located at the top of the corresponding reactor, and the discharge outlet 12 of the first reactor 1 and the discharge outlet 22 of the second reactor 2 are both located at the bottom of the corresponding reactor.

[0049] The discharge port 32 of the raw material tank 3 is connected to the inlet 11 of the first reactor 1 and the inlet 21 of the second reactor 2 via the feeding pipe 51; the inlet 41 of the finished product tank 4 is connected to the discharge port 12 of the first reactor 1 and the discharge port 22 of the second reactor 2 via the discharge pipe 52.

[0050] The feed inlet 11 of the first reactor 1 is connected to the first feed pipe 53. The other end of the first feed pipe 53 is connected to the feeding pipe 51. The feeding pipe 53 enables the connection between the feeding pipe 51 and the first reactor 1, so that the raw materials can enter the first reactor 1 and react under the catalysis of enzymes to obtain the finished product.

[0051] The feed inlet 21 of the second reactor 2 is connected to the second feed pipe 54. The other end of the second feed pipe 54 is connected to the feeding pipe 51. The feeding pipe 54 enables the connection between the feeding pipe 51 and the second reactor 2, so that the raw materials can enter the second reactor 2 and react under the catalysis of enzymes to obtain the finished product.

[0052] The discharge port 12 of the first reactor 1 is connected to the first discharge pipe 55, and the discharge port 22 of the second reactor 2 is connected to the second discharge pipe 56. Both the first discharge pipe 55 and the second discharge pipe 56 are set parallel to the horizontal plane.

[0053] The first discharge pipe 55 is connected to the first feed pipe 53 via the first circulation pipe 61. The first discharge pipe 55 is connected to the second feed pipe 54 via the second circulation pipe 62. The first discharge pipe 55 is connected to the discharge pipe 52 via the third circulation pipe 63. The third circulation pipe 63 is also connected to the first circulation pipe 61 via a branch pipe 66.

[0054] The second discharge pipe 56 is connected to the fourth circulation pipe 64 and the second feed pipe 54, and the second discharge pipe 56 is connected to the fifth circulation pipe 65 and the discharge pipe 52.

[0055] The reaction apparatus for pilot-scale enzyme-catalyzed continuous preparation of structured lipids provided in this embodiment of the present invention includes two working modes: one is an internal circulation mode in which the first reactor 1 and the second reactor 2 are used in parallel; the other is an external circulation mode in which the first reactor 1 and the second reactor 2 are used in series.

[0056] like Figure 4 As shown, in the internal circulation mode, the material passes through the green-colored pipelines. Specifically, the raw materials enter the first reactor 1 and the second reactor 2 via the first feed pipeline 53 and the second feed pipeline 54, respectively. In the first reactor 1, the raw materials react under the catalysis of enzymes and are then transported back to the first feed pipeline 53 via the first circulation pipeline 61, re-entering the first reactor 1 for further reaction until the finished product is produced. This is the internal circulation process of the first reactor 1. In the second reactor 2, the raw materials react under the catalysis of enzymes and are then transported back to the second feed pipeline 54 via the fourth circulation pipeline 64, re-entering the second reactor 2 for further reaction until the finished product is produced. This is the internal circulation process of the second reactor 2. Using the internal circulation mode for the preparation of structured lipids, the reaction processes of the first reactor 1 and the second reactor 2 do not interfere with each other. When the enzyme activity in one reactor is insufficient and needs to be replaced, only the valve on the corresponding pipeline needs to be closed for replacement, while the other reactor can continue to prepare structured lipids normally, ensuring continuous production.

[0057] like Figure 5As shown, in the external circulation mode, the material passes through the green-colored pipelines. Specifically, the raw materials enter the first reactor 1 and the second reactor 2 through the first feed pipeline 53 and the second feed pipeline 54, respectively. In the first reactor 1, the raw materials react under the catalysis of enzymes. They are then transported to the second feed pipeline 54 through the second circulation pipeline 62 and enter the second reactor 2 to react under the catalysis of enzymes. Then, they enter the fifth circulation pipeline 65 through the second discharge pipeline 56, and the third circulation pipeline 63 through the discharge pipeline 52. They then enter the first circulation pipeline 61 through the branch pipeline 66 and are transported to the first feed pipeline 53 from the first circulation pipeline 61, re-entering the first reactor 1 for reaction. This constitutes one external circulation. Multiple external circulations are performed between the first reactor 1 and the second reactor 2 until the finished product is output. The external circulation mode is suitable for situations where structured lipids have already been prepared using reactor 1 and reactor 2. In this case, the enzymes in reactor 1 and reactor 2 are not completely inactivated. The series connection of reactor 1 and reactor 2 allows for the utilization of the remaining enzyme activity for structured lipid preparation, effectively utilizing the catalytic efficiency of the enzyme molecules, maximizing resource utilization, avoiding waste, and effectively reducing production costs. During the external circulation process, the raw material initially enters either reactor 1 or reactor 2. Only one reactor is fed through the feed pipe 51, while the other reactor is fed through the external circulation.

[0058] It should be noted that in actual production, the preparation is not limited to using two reactors. The number of reactors can be increased according to the actual situation, and the switching between internal circulation mode and external circulation mode can be achieved through pipeline connection and valve control.

[0059] In one embodiment, sampling points are set in the first discharge pipe 55 and the second discharge pipe 56 to sample and inspect the output materials to determine whether the materials have been completely prepared into structured lipids and to determine the enzyme activity, thereby determining whether it is necessary to output the finished product and whether it is necessary to replace the enzyme in the reactor. When it is necessary to output the finished product, the first discharge pipe 55 conveys the material to the third circulation pipe 63, and the third circulation pipe 63 conveys the material to the discharge pipe 52, and the discharge pipe 52 conveys the material to the finished product tank 4; the second discharge pipe 56 conveys the material to the fifth circulation pipe 55, and the fifth circulation pipe 55 conveys the material to the discharge pipe 52, and the discharge pipe 52 conveys the material to the finished product tank 4.

[0060] In one embodiment, a conveying pump 8 is provided on the feeding pipe 51, the first discharge pipe 55, and the second discharge pipe 56.

[0061] In one embodiment, the third circulation pipeline 63 serves both to transport materials to the first circulation pipeline 61 for external circulation and to transport materials to the discharge pipeline 52 for discharge. Therefore, a two-position three-way valve 67 is installed between the third circulation pipeline 63 and the branch pipeline 66 to adjust the connection between the third circulation pipeline 63 and the branch pipeline 66, and between the third circulation pipeline 63 and the first discharge pipeline 55.

[0062] Specifically, in the external circulation working mode, such as Figure 5 As shown, the two-position three-way valve 67 controls the third circulation pipeline 63 to connect one side of the discharge pipeline 52 and the branch pipeline 66 to form a passage. The end of the third circulation pipeline 63 connected to the first discharge pipeline 55 is closed, and the material cannot pass through, so that the material transmitted by the fifth circulation pipeline 65 can enter the first circulation pipeline 61 and prevent it from entering the second circulation pipeline 62.

[0063] When feeding materials, such as Figure 6 As shown, the two-position three-way valve 67 controls the third circulation pipeline 63 located at both ends of the two-position three-way valve 67 to be open, and the material flow direction is in the direction of the first discharge pipeline 55 and the discharge pipeline 52; the third circulation pipeline 63 is closed between one side of the discharge pipeline 52 and the branch pipeline 66, and the material cannot pass through, so that the finished product can enter the finished product tank 4. In the internal circulation working mode, the two-position three-way valve 67 is in the normal position, and all three ports are closed.

[0064] In one embodiment, the fifth circulation pipeline 65 serves both to transport materials to the third circulation pipeline 63 for external circulation and to transport materials to the discharge pipeline 52 for discharge. Therefore, a two-position three-way valve 68 is installed between the fifth circulation pipeline 65 and the discharge pipeline 52 to adjust the connection between the fifth circulation pipeline 65 and the third circulation pipeline 63 via the discharge pipeline 52, as well as the connection between the fifth circulation pipeline 65 and the discharge pipeline 52. Specifically, the two outlets of the two-position three-way valve 68 are connected to the discharge pipeline 52 via the first branch pipeline 681 and the second branch pipeline 682, respectively. A one-way valve 69 is installed on a section of the discharge pipeline 52 located between the first branch pipeline 681 and the second branch pipeline 682.

[0065] Specifically, such as Figure 5 As shown, in the external circulation working mode, the two-position three-way valve 68 controls the fifth circulation pipeline 65 and the first branch pipeline 681 to be open, the fifth circulation pipeline 65 and the second branch pipeline 682 to be closed, and the one-way valve 69 set on the section of the material pipeline 52 between the first branch pipeline 681 and the second branch pipeline 682 to be closed, so that the material can enter the third circulation pipeline 63 for external circulation.

[0066] When cutting materials, such as Figure 6As shown, if both the first reactor 1 and the second reactor 2 have a feeding requirement, the one-way valve 69 located on the section of the material pipeline 52 between the first branch pipeline 681 and the second branch pipeline 682 is made open, and the two-position three-way valve 68 controls the fifth circulation pipeline 65 and the first branch pipeline 681 to be closed, and the fifth circulation pipeline 65 and the second branch pipeline 682 to be open, so that the first reactor 1 and the second reactor 2 simultaneously output finished products to the finished product tank 4.

[0067] If the first reactor 1 has a feeding requirement but the second reactor 2 does not, then the one-way valve 69 located on the section of the material pipeline 52 between the first branch pipeline 681 and the second branch pipeline 682 is opened, and the two-position three-way valve 68 controls the fifth circulation pipeline 65 and the first branch pipeline 681 to be closed, and the fifth circulation pipeline 65 and the second branch pipeline 682 to be closed, so that the first reactor 1 outputs the finished product to the finished product tank 4 alone.

[0068] If the first reactor 1 has no feeding requirement, but the second reactor 2 has a feeding requirement, then the one-way valve 69 located on the section of the material pipeline 52 between the first branch pipeline 681 and the second branch pipeline 682 is closed, and the two-position three-way valve 68 controls the fifth circulation pipeline 65 and the first branch pipeline 681 to be closed, while the fifth circulation pipeline 65 and the second branch pipeline 682 are open, so that the second reactor 2 outputs finished product to the finished product tank 4 independently.

[0069] In one specific embodiment, check valves 69 are provided on the first feed pipe 53, the second feed pipe 54, the first circulation pipe 61, the second circulation pipe 62, and the fourth circulation pipe 64 to ensure that the material can travel in a set direction. In the internal circulation mode, the check valves of the first circulation pipe 61 and the fourth circulation pipe 64 are open, and the check valve of the second circulation pipe 62 is closed; in the external circulation mode, the check valves of the first circulation pipe 61 and the fourth circulation pipe 64 are closed, and the check valve of the second circulation pipe 62 is open.

[0070] The first reactor 1 and the second reactor 2 have identical structures. Taking the first reactor 1 as an example, the structure of the reactor will be explained. Specifically, as follows... Figure 2-3 As shown, the first reactor 1 includes a tank 13 with a top opening, a flange cover 14 sealed and fixed to the top opening of the tank 13, and a polyester gasket (not shown) and a filter screen (not shown) covering the top opening of the tank 13. The filter screen is located on the side of the polyester gasket facing away from the flange cover 14.

[0071] The polyester gasket includes several perforations that penetrate the surfaces of both the upper and lower layers of the polyester gasket.

[0072] The feed inlet 11 of the first reactor 1 is located at the center of the flange cover 14, which is removable; the discharge outlet 12 of the first reactor 1 is located on the side wall of the tank body 13.

[0073] In this embodiment, the first reactor 1 further includes an enzyme column 15 installed inside the tank 13 and a bent pipe 16 located inside the tank 13 and communicating with the bottom of the enzyme column 15. The bent pipe 16 is used to connect the outlet of the enzyme column 15 and the discharge port 12 of the first reactor 1. The enzyme column 15 is a detachable enzyme column, which can be disassembled and replaced, ensuring the convenience and timeliness of enzyme replacement, making the preparation of structured lipids more suitable for large-scale production.

[0074] like Figure 3 As shown, the enzyme column 15 includes a cylindrical carrier 151 and an enzyme 152 filled and fixed within the cylindrical carrier 151. A bent tube 16 is connected to the outlet 1510 of the cylindrical carrier 151. The upper end of the cylindrical carrier 151 is open and communicates with the feed inlet 11 of the first reactor 1. The outlet 1510 is located at the bottom of the cylindrical carrier 151 and has a filter screen structure. The enzyme is relatively fixed within the cylindrical carrier 151, facilitating the disassembly and replacement of the entire enzyme column 15.

[0075] In this embodiment, the bent tube 16 can be fixedly installed inside the tank 13 or detachably installed inside the tank 13. When the enzyme column 15 is installed inside the tank 13, the outlet 1510 of the columnar carrier 151 needs to be aligned and connected with the bent tube 16 so that the raw material can flow out through the outlet 12 of the first reactor 1 after passing through the enzyme column 15.

[0076] The bend 16 includes a first section 161 extending vertically from the outlet 1510, a second section 162 extending parallel to the horizontal plane from the bottom of the first section 161, a third section 163 extending vertically upward from the end of the second section 162 away from the first section 161, and a fourth section 164 connecting the third section 163 and the outlet 12 of the first reactor 1. The length of the third section 163 is greater than the length of the first section 161, and the fourth section 164 is parallel to the horizontal plane.

[0077] The bend in tube 16 is designed to prevent short-circuiting. Short-circuiting refers to a situation where some raw material does not flow sufficiently through the enzyme layer inside the enzyme column 15, but instead flows rapidly from the edge or a local channel of the enzyme column 15 to the outlet. The presence of the bend in tube 16 forces the raw material to change direction when exiting the enzyme column 15, preventing it from simply flowing directly out along the enzyme column 15. This forces the fluid to redistribute, promoting a more uniform flow of raw material from inside the enzyme column 15, avoiding short-circuiting caused by excessively high local flow rates, and ensuring sufficient contact between the raw material and the enzyme.

[0078] Furthermore, both the first reactor 1 and the second reactor 2 adopt a top-in, side-out discharge method, allowing the material to flow under natural gravity, which reduces pressure drop compared to a bottom-in, top-out method. The first discharge pipe 55 and the second discharge pipe 56 are both arranged parallel to the horizontal plane. Combined with the bend 16, this reduces the material flow rate, avoids insufficient retention time of the material within the enzyme column 15, improves reaction efficiency, and also mitigates the impact of the material on the enzyme.

[0079] In one embodiment, the reaction apparatus further includes a hot water tank 7, which is equipped with a pneumatic valve and a Venton sensor, and uses a PLC automatic system to precisely control the temperature of the first reactor 1, the second reactor 2, the raw material tank 3, and the finished product tank 4.

[0080] Both the first reactor 1 and the second reactor 2 are equipped with circulating water baths 9 on the outside of their tank bodies 13. The inlet 91 of the circulating water bath 9 is located at the bottom edge of the tank body 13, and the outlet 92 of the circulating water bath 9 is located at the upper edge of the tank body 13. A circulating water pump 72 is installed at the outlet 71 of the hot water tank 7. The inlet 91 of the circulating water bath 9 is connected to the outlet 71 of the hot water tank 7, and the outlet 92 of the circulating water bath 9 is connected to the return water inlet 73 of the hot water tank 7.

[0081] The raw material tank 3 includes a tank body, an insulation layer, an automatic weighing device, a vacuum injection device, a stirring device, a temperature sensor, and a circulating water bath 9, enabling automated and precise feeding. The inlet 91 of the circulating water bath 9 is located at the bottom edge of the tank body, and the outlet 92 of the circulating water bath 9 is located at the upper edge of the tank body. The inlet 91 of the circulating water bath 9 is connected to the outlet 71 of the hot water tank 7, and the outlet 92 of the circulating water bath 9 is connected to the return outlet 73 of the hot water tank 7.

[0082] The finished product tank 4 includes a tank body, a refrigerant system, an insulation layer, and a circulating water bath 9. The inlet 91 of the circulating water bath 9 is located at the bottom edge of the tank body, and the outlet 92 of the circulating water bath 9 is located at the upper edge of the tank body. The inlet 91 of the circulating water bath 9 is connected to the outlet 71 of the hot water tank 7, and the outlet 92 of the circulating water bath 9 is connected to the return water inlet 73 of the hot water tank 7.

[0083] In one embodiment, the reaction apparatus further includes a nitrogen system (not shown in the figure), which is connected to the first reactor 1, the second reactor 2, the raw material tank 3 and the finished product tank 4 through gas guide pipes. The nitrogen discharged from the first reactor 1, the second reactor 2, the raw material tank 3 and the finished product tank 4 can be returned to the nitrogen system to form a nitrogen cycle, so as to ensure the stability of the material properties.

[0084] In one specific embodiment, both the first reactor 1 and the second reactor 2 are equipped with pressure drop caps (not shown in the figure). The pressure drop caps can reduce the impact on the enzyme when the material comes into contact with the enzyme, and avoid causing a decrease in the enzyme's catalytic activity.

[0085] The reaction apparatus for pilot-scale enzyme-catalyzed continuous preparation of structured lipids provided in this embodiment of the invention makes the apparatus more suitable for industrial production by changing the feed and discharge methods of the reactor. The pressure drop cap and bend in the reactor reduce the impact of materials on the enzyme and slow down the rate of enzyme activity decline. The use of a movable enzyme column improves the convenience and timeliness of enzyme loading and unloading, increases production efficiency, and makes it more suitable for large-scale production. By switching between internal and external circulation modes in the first and second reactors, and even more reactors, continuous preparation of structured lipids is achieved, enzyme recycling is enhanced, enzyme utilization is improved, and costs are effectively reduced.

[0086] Obviously, the above embodiments of this utility model are merely examples for clearly illustrating this utility model, and are not intended to limit the implementation of this utility model. For those skilled in the art, other variations or modifications can be made based on the above description. It is impossible to exhaustively list all the implementation methods here. All obvious variations or modifications derived from the technical solutions of this utility model are still within the protection scope of this utility model.

Claims

1. A reaction apparatus for pilot-plant enzymatic continuous production of structured lipids, characterized in that The utility model relates to a kind of reactor and its production method, including: Raw material tank, first reactor, second reactor and finished product tank; The feed inlet of the raw material tank and the finished product tank is located at the top, and the discharge outlet is located at the bottom; The first reactor and the second reactor are the same structure, and the feed inlet is located at the top, and the discharge outlet is located at the side; The discharge outlet of the raw material tank is communicated with the feed inlet of the first reactor and the second reactor respectively through upper feeding pipeline, and the feed inlet of the finished product tank is communicated with the discharge outlet of the first reactor and the second reactor respectively through lower feeding pipeline; The feed inlet of the first reactor is connected with first feeding pipeline, and the other end of the first feeding pipeline is communicated with the upper feeding pipeline; The feed inlet of the second reactor is connected with second feeding pipeline, and the other end of the second feeding pipeline is communicated with the upper feeding pipeline; The discharge outlet of the first reactor is connected with first discharge pipeline, and the discharge outlet of the second reactor is connected with second discharge pipeline, and the first discharge pipeline and the second discharge pipeline are arranged parallel to the horizontal plane; The first discharge pipeline is communicated with the first feeding pipeline through first circulation pipeline, communicated with the second feeding pipeline through second circulation pipeline, communicated with the lower feeding pipeline through third circulation pipeline, and the third circulation pipeline is communicated with the first circulation pipeline through branch pipeline; The second discharge pipeline is communicated with the second feeding pipeline through fourth circulation pipeline, and communicated with the lower feeding pipeline through fifth circulation pipeline.

2. The reaction apparatus for pilot-scale enzymatic continuous production of structural lipids according to claim 1, characterized in that, A two-position three-way valve is arranged between the third circulation pipeline and the branch pipeline to adjust the communication relationship between the third circulation pipeline and the branch pipeline, and the third circulation pipeline and the first discharge pipeline. A three-position three-way valve is arranged between the fifth circulation pipeline and the lower feeding pipeline to adjust the communication relationship between the fifth circulation pipeline and the third circulation pipeline through the lower feeding pipeline, and the communication relationship between the fifth circulation pipeline and the lower feeding pipeline.

3. The reaction device for pilot-scale enzymatic continuous production of structural lipids according to claim 1, characterized in that, A one-way valve is arranged on the first feeding pipeline, the second feeding pipeline, the first circulation pipeline, the second circulation pipeline and the fourth circulation pipeline.

4. The reaction device for pilot-scale enzymatic continuous production of structural lipids according to claim 1, characterized in that, The reactor includes a tank body with a top opening, a flange cover sealingly fixed at the top opening of the tank body, and a polyester gasket and a filter screen covering the top opening of the tank body, wherein the filter screen is located on the side of the polyester gasket away from the flange cover; The polyester gasket includes a plurality of hollow holes penetrating the upper and lower surfaces of the polyester gasket; The feed inlet of the reactor is located at the center of the flange cover, and the discharge outlet of the reactor is located at the side wall of the tank body.

5. The reaction apparatus for pilot-scale enzymatic continuous production of structural lipids according to claim 4, characterized in that, The reactor further includes an enzyme column installed in the tank body and an elbow pipe located in the tank body and communicating with the bottom of the enzyme column; The enzyme column includes a cylindrical carrier and enzymes packed and fixed in the cylindrical carrier, and the elbow pipe is connected to the outlet of the cylindrical carrier; The upper end of the cylindrical carrier is open, the outlet of the cylindrical carrier is located at the bottom of the cylindrical carrier, and the outlet is a filter screen structure.

6. The reaction apparatus for pilot-scale enzymatic continuous production of structural lipids according to claim 5, characterized in that, The elbow pipe comprises a first section connected to the outlet and extending in a vertical direction, a second section extending from the bottom of the first section and parallel to a horizontal plane, a third section extending upward from one end of the second section away from the first section in a vertical direction, and a fourth section connecting the third section and a discharge port on the side wall of the tank body; The length of the third section is greater than that of the first section, and the fourth section is arranged parallel to the horizontal plane.

7. The reaction device for pilot-scale enzymatic continuous production of structural lipids according to claim 1, characterized in that, The reaction device further comprises a hot water tank. The first reactor and the second reactor are both provided with a circulating water bath, the water inlet of the circulating water bath is located at the bottom edge of the corresponding first reactor and second reactor, and the water outlet of the circulating water bath is located at the upper edge of the corresponding first reactor and second reactor. The water outlet of the hot water tank is provided with a circulating water pump, the water inlets of the circulating water baths are connected to the water inlet of the hot water tank, and the water outlets of the circulating water baths are connected to the water inlet of the hot water tank.

8. The reaction device for pilot-scale enzymatic continuous production of structural lipids according to claim 1, characterized in that, The reaction device further comprises a nitrogen gas system, which is connected to the first reactor, the second reactor, the raw material pipe and the finished product tank through a gas guide pipe.

9. The reaction device for pilot-scale enzymatic continuous production of structural lipids according to claim 1, characterized in that, The raw material tank is provided with an automatic weighing device, a vacuum sampling device and a stirring device.

10. The reaction device for pilot-scale enzymatic continuous production of structural lipids according to claim 1, characterized in that, The first reactor and the second reactor are both provided with a pressure drop cap.

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