Urine sample collection and preservation device

Abstract

The utility model discloses a urine sample collection and preservation device, which belongs to the technical field of sample experiment reaction and comprises a preservation container and a collection container, the collection container is sleeved outside the preservation container and is detachably matched with the preservation container, the collection container is provided with an open collection cavity, and the preservation container is provided with a sealed storage cavity; the storage container is of a transparent structure and is provided with at least a first scale mark and a second scale mark, in the storage cavity, a first capacity space is formed between the first scale mark and the bottom of the storage container, and a second capacity space is formed between the second scale mark and the bottom of the storage container. The volume of the second capacity space is larger than that of the first capacity space. The first scale mark and the second scale mark are used as marks, the preserving fluid is quantitatively added, the urine sample and the preserving fluid are quantitatively mixed and preserved, it is ensured that the urine sample is relatively stable, cells in the urine sample are well preserved, and the accuracy of detection data is obviously improved.

Description

Technical Field

[0001] This utility model relates to the technical field of medical testing instruments, and in particular to a urine sample collection and preservation device. Background Technology

[0002] Urine testing is an important clinical diagnostic tool for urinary system diseases (such as urinary tract infections, bladder cancer, and kidney disease). Exfoliated cells in urine (such as urothelial cells and leukocytes) can be used for cytological analysis (such as urine cytology), molecular detection (such as FISH and PCR), and immunological detection (such as tumor marker screening). However, cells in urine samples have poor stability in vitro, mainly facing the problem of rapid cell degradation. After being removed from the in vivo environment, cells in urine are prone to apoptosis, lysis, or bacterial contamination, leading to false negatives or data bias in the test results. Utility Model Content

[0003] The purpose of this invention is to improve the problem that existing urine samples cannot be quantitatively and proportionally preserved after collection, and to provide a urine sample collection and preservation device.

[0004] The technical solutions for achieving the above objectives include the following:

[0005] A urine sample collection and preservation device includes a preservation container and a collection container. The collection container is fitted over the preservation container and is detachably connected to the preservation container. The collection container has an open collection cavity, and the preservation container has a sealed storage cavity.

[0006] The storage container is transparent and has at least a first scale mark and a second scale mark. In the storage cavity, a first capacity space is formed between the first scale mark and the bottom of the storage container. The first capacity space is used to hold the storage liquid. A second capacity space is formed between the second scale mark and the bottom of the storage container. The volume of the second capacity space is larger than the volume of the first capacity space.

[0007] In one embodiment, the storage container further has a third scale mark, and the first scale mark, the second scale mark, and the third scale mark are sequentially located on the outer wall of the storage container, and the third scale mark forms a third capacity space between the third scale mark and the bottom of the storage container;

[0008] The collection container is a transparent structure. The collection container has a fourth scale mark and a fifth scale mark. The fourth scale mark and the bottom of the collection container form a fourth capacity space, and the fifth scale mark and the bottom of the collection container form a fifth capacity space.

[0009] In one embodiment, the total volume of the third capacity space minus the volume of the first capacity space equals the added volume of the third capacity space, and the volume of the fifth capacity space is greater than the added volume of the third capacity space.

[0010] In one embodiment, the storage container includes a first outer shell and a second outer shell, the first outer shell being mounted on the second outer shell, the outer diameter of the first outer shell being smaller than the outer diameter of the second outer shell, the inner diameter of the collection container being larger than the outer diameter of the first outer shell and smaller than the outer diameter of the second outer shell, and the open end of the collection container being used to abut against the second outer shell.

[0011] In one embodiment, the collection container includes a third outer shell and a fourth outer shell, the third outer shell and the fourth outer shell being an integral structure, the outer diameter of the third outer shell being larger than the outer diameter of the fourth outer shell, and the inner diameter of the third outer shell being larger than the outer diameter of the first outer shell.

[0012] In one embodiment, the collection container further has at least two positioning plates, both of which are installed on the inner wall of the fourth outer shell and are arranged opposite to each other.

[0013] Each positioning plate has a guide ramp, which faces the opening of the collection container.

[0014] In one embodiment, the collection container has a handle and a flow guide, which are disposed at the opening of the collection container and are offset from each other in the radial direction of the collection container.

[0015] In one embodiment, a first line is formed between the flow guide and the axis of the collection container, and a second line is formed between the handheld part and the axis of the collection container. The angle formed by the intersection of the first line and the second line is 85 to 95 degrees.

[0016] In one embodiment, the collection container is circular when viewed from above, and a square receiving area is formed by connecting the four tangent points outside the collection container. The shape of the inscribed circle of the receiving area matches the outer edge of the collection container. The guide part and the handheld part are located inside the receiving area and are positioned near the top corner of the receiving area.

[0017] In one embodiment, the storage container includes a bottle body, an identification ring, a limiting ring, and a bottle cap. The bottle cap has an internal thread, the opening of the bottle body has an external thread, and the bottle cap is threadedly connected to the bottle body.

[0018] The limiting ring is fitted onto the opening of the bottle body and positioned below the external thread. A limiting groove is formed between the limiting ring and the bottom of the external thread. The marking ring is movably fitted into the limiting groove and is detachably connected to the bottle cap.

[0019] The technical solution provided by this utility model has the following advantages and effects:

[0020] When adding the preservation solution, the first graduation mark can be used as a marker. The solution is added to the first graduation mark to ensure quantitative addition. When adding urine samples from the collection container to the preservation container, the urine sample is observed until it reaches the second graduation mark, achieving quantitative mixing and preservation of the urine sample and preservation solution. This quantitative collection of urine samples by the preservation container ensures a relatively stable ratio of urine sample to preservation solution, resulting in well-preserved cells in the urine sample and significantly improving the accuracy of the test data. Attached Figure Description

[0021] The accompanying drawings illustrate specific examples of the technical solutions described in this utility model, and together with the detailed embodiments, form part of the specification, serving to explain the technical solutions, principles, and effects of this utility model.

[0022] Unless otherwise specified or defined, the same reference numerals in different figures represent the same or similar technical features, and different reference numerals may be used to represent the same or similar technical features.

[0023] Figure 1 This is a schematic diagram of the data acquisition and storage device in one embodiment of the present invention;

[0024] Figure 2 This is an exploded view of the data collection and storage device in one embodiment of this utility model;

[0025] Figure 3 This is a schematic diagram of a storage container in one embodiment of the present invention;

[0026] Figure 4 This is a schematic diagram of the collection container in one embodiment of the present invention;

[0027] Figure 5 This is a top view of the collection container in one embodiment of the present invention;

[0028] Figure 6 This is a cross-sectional view of the collection container in one embodiment of this utility model;

[0029] Figure 7 This is a schematic diagram of the installation of the marking ring in one embodiment of this utility model. Figure 1 ;

[0030] Figure 8 This is a schematic diagram of the installation of the marking ring in one embodiment of this utility model. Figure 2 ;

[0031] Figure 9 This is a schematic diagram of the marking ring in one embodiment of the present invention;

[0032] Explanation of reference numerals in the attached figures:

[0033] 100. Collection and preservation device; 1. Preservation container; 10. Storage cavity; 11. Bottle body; 111. First outer shell; 112. Second outer shell; 113. Limiting ring; 114. External thread; 115. Limiting groove; 12. Bottle cap; 13. First scale mark; 14. Second scale mark; 15. Third scale mark; 2. Collection container; 20. Collection cavity; 21. Flow guide; 22. Handheld part; 23. Third outer shell; 24. Fourth outer shell; 25. Fourth scale mark; 26. Fifth scale mark; 27. First connecting line; 28. Second connecting line; 29. ​​Positioning plate; 291. Guide slope; 201. Receiving area; 3. Identifying ring; 31. Broken protrusion. Detailed Implementation

[0034] To facilitate understanding of this utility model, the specific embodiments of this utility model will be described in more detail below with reference to the accompanying drawings.

[0035] Unless otherwise specified or defined, the terms "first," "second," etc., used in this document are for distinguishing names only and do not represent a specific number or order.

[0036] Unless otherwise stated or defined, the term “and / or” as used herein includes any and all combinations of one or more of the associated listed items.

[0037] It should be noted that when a component is considered "fixed" to another component, it can be directly fixed to the other component or there can be an intervening component; when a component is considered "connected" to another component, it can be directly connected to the other component or there can be an intervening component; when a component is considered "mounted" on another component, it can be directly mounted on the other component or there can be an intervening component; when a component is considered "placed" on another component, it can be directly placed on the other component or there can be an intervening component.

[0038] This utility model proposes a urine sample collection and preservation device 100, such as... Figures 1 to 6As shown, the device includes a storage container 1 and a collection container 2. The collection container 2 is fitted over the storage container 1 and is detachably connected to the storage container 1. The collection container 2 has an open collection cavity 20, and the storage container 1 has a sealed storage cavity 10. The storage container 1 is a transparent structure and has at least a first scale mark 13 and a second scale mark 14. In the storage cavity 10, a first capacity space is formed between the first scale mark 13 and the bottom of the storage container 1. The first capacity space is used to hold the storage liquid. A second capacity space is formed between the second scale mark 14 and the bottom of the storage container 1. The volume of the second capacity space is larger than the volume of the first capacity space.

[0039] Specifically, collection container 2 is used to collect urine samples, and storage container 1 is used to store urine samples. During use, a fixed amount of preservation solution can be added to storage container 1, which is then sealed. After collecting a urine sample, collection container 2 opens storage container 1, pours the urine sample into it, mixes it with the preservation solution, and then seals storage container 1 again. Storage container 1 improves the airtightness of the urine sample, preventing external contamination. Adding preservation solution to storage container 1 beforehand extends the storage time of the urine sample. In this embodiment, the preservation solution can be replaced with an RNA protectant or bacterial culture medium to meet various testing needs. The color of the cap 12 can be used for visual differentiation and indication. Furthermore, this collection and storage device 100 eliminates the need to open storage container 1 twice to add preservation solution, reducing contact for testing personnel, lowering the risk of infection, and saving operation time. Collection container 2 is disposable after use, facilitating centralized processing.

[0040] Furthermore, the preservation container 1 is transparent, facilitating observation of the liquid level within it. The preservation container 1 has a first graduation mark 13 and a second graduation mark 14. A first volume space is formed between the first graduation mark 13 and the bottom of the preservation container 1, which holds the preservation solution. A second volume space is formed between the second graduation mark 14 and the bottom of the preservation container 1, which holds both the preservation solution and the urine sample. The volume of the second volume space is larger than that of the first volume space. When adding the preservation solution, the first graduation mark 13 can be used as a marker; the solution is added to the first graduation mark 13 for quantitative addition. When the collection container 2 adds the urine sample to the preservation container 1, the urine sample is added to the second graduation mark 14 by observing the preservation container 1, achieving quantitative mixing and preservation of the urine sample and preservation solution. The preservation container 1 quantitatively collects the urine sample, ensuring a relatively stable ratio of urine sample to preservation solution and good preservation of cells in the urine sample, significantly improving the accuracy of the detection data.

[0041] Preferably, the storage container 1 can have a reserved QR code label area to support subsequent information management.

[0042] Preferably, the storage container 1 also has a third scale mark 15, and the first scale mark 13, the second scale mark 14, and the third scale mark 15 are located on the outer wall of the storage container 1 in sequence, forming a third capacity space between the third scale mark 15 and the bottom of the storage container 1; the collection container 2 is a transparent structure, and the collection container 2 has a fourth scale mark 25 and a fifth scale mark 26, forming a fourth capacity space between the fourth scale mark 25 and the bottom of the collection container 2, and forming a fifth capacity space between the fifth scale mark 26 and the bottom of the collection container.

[0043] Specifically, the third volumetric space is larger than the second volumetric space, enabling the preservation of urine samples and preservation solutions with different quantitative ratios, thus improving the flexibility of the preservation container 1. Furthermore, the collection container 2 has a transparent structure, facilitating observation of the liquid level within it. The collection container 2 has a fourth graduation mark 25 and a fifth graduation mark 26, allowing for the quantitative collection of urine. The quantitatively collected urine is then poured into the preservation container 1, further enhancing the ease of use of the collection and preservation device 100.

[0044] Preferably, the total volume of the third capacity space minus the volume of the first capacity space equals the added volume of the third capacity space, and the volume of the fifth capacity space is greater than the added volume of the third capacity space. Specifically, after the preservation solution is added to the first capacity space, the preservation container 1 can still add urine samples with at least the added volume of the third capacity space; and the volume of the fifth capacity space of the collection container 2 is greater than the added volume of the third capacity space. Therefore, the urine sample collected by the collection container 2 can at least cover the added volume of the third capacity space, further meeting the urine collection capacity requirement of the preservation container 1.

[0045] Preferably, the storage container 1 includes a first outer shell 111 and a second outer shell 112. The first outer shell 111 is mounted on the second outer shell 112. The outer diameter of the first outer shell 111 is smaller than the outer diameter of the second outer shell 112. The inner diameter of the collection container 2 is larger than the outer diameter of the first outer shell 111 and smaller than the outer diameter of the second outer shell 112. The open end of the collection container 2 is used to abut against the second outer shell 112. Specifically, the collection container 2 is used to fit over the first outer shell 111, so that the inner wall of the collection container 2 fits against the outer wall of the first outer shell 111, and the open end of the collection container 2 abuts against the second outer shell 112, thereby improving the stability of the collection container 2 fitted over the first outer shell 111. At the same time, fitting the collection container 2 over the first outer shell 111 can reduce the size of the collection and storage device 100, making it easier to handle and transport.

[0046] Furthermore, the outer diameter of the first outer shell 111 is smaller than the outer diameter of the second outer shell 112, and a step is formed at the junction of the upper and lower parts of the storage container 1. When the collection container 2 is fitted over the first outer shell 111, the outer wall of the collection and storage device 100 is flush with it, forming a visually unified closed effect.

[0047] Preferably, the storage container 1 is made of transparent PET material, has a volume of 150mL, and is pre-filled with 30mL of storage solution. The first graduation mark 13 on the storage container 1 is 50mL, the second graduation mark 14 is 100mL, and the third graduation mark 15 is 150mL. The total height of the storage container 1 is 98mm, the diameter of the second outer shell 112 is 57mm, the diameter of the first outer shell 111 is 54mm, and a 1.5mm drop step is formed at the junction. The inner diameter of the opening of the storage container 1 is 30mm.

[0048] Preferably, the collection container 2 includes a third outer shell 23 and a fourth outer shell 24, which are integrally formed. The outer diameter of the third outer shell 23 is larger than that of the fourth outer shell 24, and the inner diameter of the third outer shell 23 is larger than that of the first outer shell 111. Specifically, the inner wall of the third outer shell 23 is used to fit against the outer wall of the first outer shell 111, and the inner wall of the fourth outer shell 24 is used to fit against the outer wall of the bottle cap 12, further improving the stability of the collection container 2 when it is fitted over the storage container 1.

[0049] Preferably, the collection container 2 also has at least two positioning plates 29, both of which are installed on the inner wall of the fourth outer shell 24 and are arranged opposite to each other. When the collection container 2 is fitted onto the storage container 1, the bottom of the collection container 2 is used to engage with the bottle cap 12 of the storage container 1, and the four positioning plates 29 are used to abut against the outer wall of the bottle cap 12 to position the bottle cap 12 as it enters the collection container 2. Each positioning plate 29 has a guide slope 291 facing the opening of the collection container 2. The guide slope 291 is used to guide the bottle cap 12 into the bottom of the collection container 2, improving the efficiency of the assembly of the collection container 2 and the storage container 1.

[0050] Preferably, the collection container 2 has a handle 22 and a flow guide 21, which are located at the opening of the collection container 2 and are offset radially from each other. Specifically, the user holds the handle 22 and urinates naturally into the collection container 2. The user tilts the collection container 2, and the urine from the collection container 2 flows through the flow guide 21 into the storage container 1, where the storage solution and urine are automatically mixed. Furthermore, the handle 22 allows the user to hold the main body of the collection container 2 while keeping their hand away from the rim, preventing urine from splashing onto their hands when collecting urine.

[0051] Furthermore, the collection container 2 is circular when viewed from above. A square receiving area 201 is formed by connecting the four tangent points on the outside of the collection container 2. The inscribed circle of this receiving area 201 matches the outer edge of the collection container 2. The guide portion 21 and the handle portion 22 are located within the receiving area 201 and are positioned near its apex. Specifically, when multiple collection and preservation devices 100 are packaged, the handle portion 22 or guide portion 21 of one collection and preservation device 100 will not interfere with the other. Multiple collection and preservation devices 100 can be neatly arranged, resulting in higher space utilization during packaging.

[0052] Preferably, a first connecting line 27 is formed between the flow guide 21 and the axis of the collection container 2, and a second connecting line 28 is formed between the handle 22 and the axis of the collection container 2. The angle formed by the intersection of the first connecting line 27 and the second connecting line 28 is 85 to 95 degrees. Specifically, the angle formed by the intersection of the first connecting line 27 and the second connecting line 28 is 90 degrees. With the handle 22 and the flow guide 21 located on one side, it is helpful to complete the pouring action.

[0053] Preferably, the collection container 2 is made of PET material and has a total volume of 110mL; the inner diameter of the opening of the collection container 2 is 55mm, the handle part 22 is an isosceles triangle with a base length of 23mm and a height of 10mm; the guide part 21 is funnel-shaped with an inlet width of 22mm, an outlet width of 9mm, and a depth of 9mm; the fourth scale mark 25 of the collection container 2 is 50mL, and the fifth scale mark 26 is 100mL.

[0054] To improve the reliability of the data acquisition and storage device 100, in some embodiments, such as... Figures 7 to 9 As shown, the storage container 1 includes a bottle body 11, an identification ring 3, a limiting ring 113, and a bottle cap 12. The bottle cap 12 has an internal thread, and the opening of the bottle body 11 has an external thread 114. The bottle cap 12 is threadedly connected to the bottle body 11. The limiting ring 113 is fitted onto the opening of the bottle body 11 and is located below the external thread 114. A limiting groove 115 is formed between the bottom of the limiting ring 113 and the external thread 114. The identification ring 3 is movably fitted into the limiting groove 115, and the identification ring 3 is detachably connected to the bottle cap 12.

[0055] Specifically, after the preservation liquid is added to the storage container 1, the cap 12 is threadedly connected to the bottle body 11 to seal the storage cavity 10. The marking ring 3 on the cap 12 is confined within the limiting groove 115. When the cap is opened, the marking ring 3 breaks off and remains at the bottle opening, and cannot be restored. A clear break mark is visible after the cap 12 is opened, indicating the open state of the storage container 1. Furthermore, the threaded connection between the bottle body 11 and the cap 12 ensures the reliability of the seal of the storage container 1.

[0056] Preferably, the upper end of the marking ring 3 has multiple broken protrusions 31, each broken protrusion 31 being detachably connected to the bottom of the bottle cap 12. Specifically, after the bottle cap 12 is opened, each broken protrusion 31 shows obvious breakage marks.

[0057] When referencing drawings, new features are explained. To avoid redundant references to drawings that would make the description less concise, features already described will not be referenced again on the drawings if the description is clear.

[0058] The purpose of the above embodiments is to reproduce and derive the technical solution of this utility model by way of example, and to fully describe the technical solution, purpose and effect of this utility model. The purpose is to enable the public to have a more thorough and comprehensive understanding of the disclosed content of this utility model, and it is not intended to limit the protection scope of this utility model.

[0059] The above embodiments are not an exhaustive list based on the present invention, and there may be other embodiments not listed. Any substitutions and improvements made without departing from the concept of the present invention are within the protection scope of the present invention.

Claims

1. A urine sample collection and preservation device, characterized in that, It includes a storage container and a collection container. The collection container is fitted over the storage container and is detachably connected with the storage container. The collection container has an open collection cavity, and the storage container has a sealed storage cavity. The storage container is at least partially transparent and has at least a first scale mark and a second scale mark. In the storage cavity, a first capacity space is formed between the first scale mark and the bottom of the storage container. The first capacity space is used to hold the storage liquid. A second capacity space is formed between the second scale mark and the bottom of the storage container. The volume of the second capacity space is larger than the volume of the first capacity space.

2. The urine sample collection and preservation device of claim 1, wherein The storage container also has a third scale mark. The first scale mark, the second scale mark, and the third scale mark are located on the outer wall of the storage container in sequence, and the third scale mark forms a third capacity space between the storage container and the bottom of the storage container. The collection container is a transparent structure. The collection container has a fourth scale mark and a fifth scale mark. The fourth scale mark and the bottom of the collection container form a fourth capacity space, and the fifth scale mark and the bottom of the collection container form a fifth capacity space.

3. The urine sample collection and preservation device of claim 2, wherein The total volume of the third capacity space minus the volume of the first capacity space equals the added volume of the third capacity space, and the volume of the fifth capacity space is greater than the added volume of the third capacity space.

4. The urine sample collection and preservation device as described in claim 1, characterized in that, The storage container includes a first outer shell and a second outer shell. The first outer shell is installed on the second outer shell. The outer diameter of the first outer shell is smaller than the outer diameter of the second outer shell. The inner diameter of the collection container is larger than the outer diameter of the first outer shell and smaller than the outer diameter of the second outer shell. The open end of the collection container is used to abut against the second outer shell.

5. The urine sample collection and preservation device of claim 4, wherein The collection container includes a third outer shell and a fourth outer shell, which are integral structures. The outer diameter of the third outer shell is larger than that of the fourth outer shell, and the inner diameter of the third outer shell is larger than that of the first outer shell.

6. The urine sample collection and preservation device of claim 5, wherein The collection container also has at least two positioning plates, both of which are installed on the inner wall of the fourth outer shell and are arranged opposite to each other. Each positioning plate has a guide ramp, which faces the opening of the collection container.

7. The urine sample collection and preservation device according to any one of claims 1 to 6, wherein The collection container has a handheld part and a flow guide part, which are located at the opening of the collection container and are offset from each other in the radial direction of the collection container.

8. The urine sample collection and preservation device of claim 7, wherein, A first line is formed between the flow guide and the axis of the collection container, and a second line is formed between the handheld part and the axis of the collection container. The angle formed by the intersection of the first line and the second line is 85 to 95 degrees.

9. The urine sample collection and preservation device of claim 7, wherein The collection container is circular when viewed from above. The four tangent points on the outside of the collection container form a square receiving area. The shape of the inscribed circle of the receiving area matches the outer edge of the collection container. The guide part and the handheld part are located in the receiving area and are set near the top corner of the receiving area.

10. The urine sample collection and preservation device of any one of claims 1 to 6, wherein, The storage container includes a bottle body, a label ring, a limiting ring, and a bottle cap. The bottle cap has an internal thread, the opening of the bottle body has an external thread, and the bottle cap is threadedly connected to the bottle body. The limiting ring is sleeved at the opening of the bottle body and is arranged below the outer thread, a limiting groove is formed between the limiting ring and the bottom of the outer thread, the identification ring is movably sleeved in the limiting groove, and the identification ring is detachably connected with the bottle cap.

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