Auxiliary key and switch cover equipment capable of realizing automatic operation of nucleic acid amplification instrument

Abstract

When the auxiliary key and switch cover equipment capable of realizing automatic operation of the nucleic acid amplification instrument is used, a lead screw driving device drives a lead screw to rotate around the front-back direction, a middle connecting plate is moved front and back, a heat cover left-right clamping plate is further moved front and back, and thus a PCR instrument heat cover is moved front and back; the elastic key head is moved left and right through the transverse movement driving device; the longitudinal movement driving device drives the elastic key head to move along the inclined direction of the longitudinal movement guide rail; the elastic key head is stretched out and drawn back through the key head stretching-retracting device, and the simulated key pressing action is executed; information displayed by the display screen of the panel is shot through the camera, and whether key operation is correctly completed or not is determined according to the information displayed by the display screen. The device can be matched with the existing nucleic acid amplification instrument, the cover and the auxiliary key can be automatically opened and closed, and the device can be conveniently combined with full-automatic biochemical experiment equipment, so that the laboratory cost is greatly saved, and the popularization and the use of the full-automatic biochemical experiment equipment are facilitated.

Description

Technical Field

[0001] This utility model relates to the field of biochemical research technology, and in particular to the field of nucleic acid amplification instrument operation technology, specifically referring to an auxiliary button and switch cover device that enables automatic operation of a nucleic acid amplification instrument. Background Technology

[0002] Biochemical research, or biochemical studies for short, is mainly used to study the structure and function of various components within cells, such as proteins, carbohydrates, lipids, nucleic acids, and other biological macromolecules.

[0003] A nucleic acid amplification instrument (PCR instrument) is a common instrument in biochemistry laboratories. It replicates nucleic acid template molecules in large quantities through PCR reactions to achieve the detection of ultra-small amounts of nucleic acid molecules. While the technology for developing PCR instruments is mature, these instruments, being relatively old, are primarily operated manually and lack the capability to be integrated with fully automated biochemistry experimental equipment. Achieving fully automated biochemistry experiments typically requires the development of entirely new PCR instruments that can be automatically adapted. Currently, biochemistry laboratories are equipped with a large number of high-performance PCR instruments that perform well and are not yet obsolete. If these manually operated PCR instruments could be fully automated, it would significantly reduce laboratory costs and facilitate the widespread adoption of fully automated biochemistry experimental equipment.

[0004] Therefore, it is desirable to develop an auxiliary button and cover opening / closing device that enables automatic operation of nucleic acid amplification instruments. This device should be compatible with existing nucleic acid amplification instruments, enabling automatic cover opening / closing and auxiliary button operation, so as to be used in conjunction with fully automated biochemical experimental equipment. This would greatly save laboratory costs and facilitate the widespread use of fully automated biochemical experimental equipment. Utility Model Content

[0005] In order to overcome the shortcomings of the prior art, one objective of this utility model is to provide an auxiliary button and cover opening / closing device that enables automatic operation of a nucleic acid amplification instrument. This device is compatible with existing nucleic acid amplification instruments and enables automatic cover opening / closing and auxiliary button operation, so as to be used in conjunction with fully automated biochemical experimental equipment. This greatly saves laboratory costs, facilitates the promotion and use of fully automated biochemical experimental equipment, and is suitable for large-scale application.

[0006] Another objective of this invention is to provide an auxiliary button and switch cover device that enables automatic operation of a nucleic acid amplification instrument. It is ingeniously designed, has a simple structure, is easy to manufacture, has low manufacturing cost, and is suitable for large-scale promotion and application.

[0007] To achieve the above objectives, this utility model provides an auxiliary button and switch cover device for automatic operation of a nucleic acid amplification instrument. Its features include a base plate, an auxiliary button mechanism, a PCR instrument hot-cover switch cover mechanism, and a camera recognition mechanism, wherein:

[0008] The base plate is horizontally positioned along the front-to-back direction and is used to support the PCR instrument.

[0009] The auxiliary button mechanism includes a left support, a right support, a transverse moving base plate, a transverse moving guide rail, a transverse moving drive device, a longitudinal moving base plate, a longitudinal moving guide rail, a longitudinal moving drive device, a button head telescopic device, and a flexible button head. The left and right supports are spaced apart on the base plate and positioned on the left and right sides of the PCR instrument. The transverse moving base plate is positioned along the left-right direction and inclined upwards and backwards, positioned above the rear side of the PCR instrument's panel. The left and right ends of the transverse moving base plate are respectively mounted on the left and right supports. The transverse moving guide rail is positioned along the left-right direction and along the inclined direction of the transverse moving base plate. The longitudinal moving base plate is positioned along the left-right direction and inclined upwards and backwards, positioned above the panel and parallel to the panel. The rear end of the longitudinally moving base plate is movably mounted on the transversely moving guide rail. The transversely moving drive device is mounted on the transversely moving base plate and connected to the rear end of the longitudinally moving base plate to drive the longitudinally moving base plate to move left and right. The longitudinally moving guide rail is arranged along the left-right direction and along the inclined direction of the longitudinally moving base plate. The elastic button head is located on the right side of the longitudinally moving base plate and is perpendicular to the longitudinally moving base plate and is used to face the button area of ​​the panel. The button head telescopic device is movably mounted on the longitudinally moving guide rail along the inclined direction of the longitudinally moving guide rail and connected to the elastic button head to extend and retract the elastic button head in a direction perpendicular to the longitudinally moving base plate. The longitudinally moving drive device is mounted on the longitudinally moving base plate and connected to the button head telescopic device to drive the button head telescopic device to move along the inclined direction of the longitudinally moving guide rail.

[0010] The PCR instrument's hot cover opening and closing mechanism includes a left hot cover locking plate, a right hot cover locking plate, a middle connecting plate, a lead screw, a lead screw drive device, and a drive device fixing base. Both the left and right hot cover locking plates are vertically arranged and aligned along the front-to-back direction, spaced apart from each other. The bottom of the left and right hot cover locking plates each have a left hot cover slot and a right hot cover slot, respectively, arranged along the left-to-right direction. These slots are spaced apart and both are used to engage with the hot cover of the PCR instrument. The middle connecting plate is vertically arranged and aligned along the left-to-right direction. The left and right ends of the connecting plate are located behind the rear ends of the left and right heat cover plates, respectively, and are connected to the rear ends of the left and right heat cover plates, respectively. The lead screw is arranged along the front-back direction, and the front end of the lead screw passes through and threadedly engages the middle part of the intermediate connecting plate along the front-back direction. The drive device mounting base is located behind the intermediate connecting plate and is used to be located behind the PCR instrument and installed on the body of the PCR instrument. The lead screw drive device is installed on the drive device mounting base and connected to the rear end of the lead screw for driving the lead screw to rotate around the front-back direction.

[0011] The camera identification mechanism includes a camera, a camera support frame, a camera mounting plate, and a camera fixing plate. The camera support frame is mounted on the base plate and positioned in front of the right side of the PCR instrument. The camera fixing plate and the camera mounting plate are both vertically arranged and along the front-back direction, and are mutually abutting each other. The camera mounting plate is located to the left of the camera support frame and is connected to the camera support frame. The camera fixing plate is connected to the camera mounting plate and is adjustable in angle relative to the camera mounting plate in the left-right direction. The camera is located to the left of the camera fixing plate and is mounted on the camera fixing plate, facing the display screen of the panel.

[0012] Preferably, the left support and the right support are a left support plate and a right support plate, respectively, and both the left support plate and the right support plate are vertically arranged and are arranged along the front-back direction.

[0013] Preferably, the lateral movement drive device includes a lateral movement driven wheel, a lateral movement driving wheel, a lateral movement timing belt, a lateral movement drive component, and a lateral movement slider. The lateral movement driven wheel and the lateral movement driving wheel are both parallel to the lateral movement base plate and spaced apart from each other on the left and right sides. They are both rotatably mounted on the lateral movement base plate in a direction perpendicular to the lateral movement base plate. The lateral movement drive component is mounted on the lateral movement base plate and connected to the lateral movement driving wheel to drive the lateral movement driving wheel to rotate in a direction perpendicular to the lateral movement base plate. The lateral movement slider is movably mounted on the lateral movement guide rail on the left and right sides. The rear end of the longitudinal movement base plate is mounted on the lateral movement slider. The lateral movement timing belt is positioned along the left and right directions and along the inclined direction of the lateral movement base plate, and is located behind the lateral movement guide rail. The left and right ends of the lateral movement timing belt are respectively sleeved on the lateral movement driven wheel and the lateral movement driving wheel. The front part of the lateral movement timing belt is connected to the lateral movement slider.

[0014] Preferably, the longitudinal movement drive device includes a longitudinal movement driven wheel, a longitudinal movement driving wheel, a longitudinal movement timing belt, a longitudinal movement drive component, and a longitudinal movement slider. The longitudinal movement driven wheel and the longitudinal movement driving wheel are both parallel to the longitudinal movement base plate and are spaced apart from each other along the inclined direction of the longitudinal movement base plate. Both are rotatably mounted on the longitudinal movement base plate in a direction perpendicular to the longitudinal movement base plate. The longitudinal movement drive component is mounted on the longitudinal movement base plate and connected to the longitudinal movement driving wheel to drive the longitudinal movement driving wheel to rotate in a direction perpendicular to the longitudinal movement base plate. The longitudinal movement slider is movably mounted on the longitudinal movement guide rail along the inclined direction of the longitudinal movement guide rail. The button head telescopic device is mounted on the longitudinal movement slider. The longitudinal movement timing belt is positioned along the left-right direction and along the inclined direction of the longitudinal movement base plate, located on the left side of the longitudinal movement guide rail. The front end and rear end of the longitudinal movement timing belt are respectively sleeved on the longitudinal movement driven wheel and the longitudinal movement driving wheel. The right side of the longitudinal movement timing belt is connected to the longitudinal movement slider.

[0015] Preferably, the button head telescopic device is a push rod motor.

[0016] Preferably, the drive device mounting base includes a drive device mounting plate and a mounting plate connector. The mounting plate connector is located behind and connected to the body of the PCR instrument. The drive device mounting plate is vertically arranged and positioned along the left-right direction. The drive device mounting plate is mounted on the mounting plate connector and located behind the intermediate connecting plate. The lead screw drive device is located behind the drive device mounting plate and mounted on the drive device mounting plate. The rear end of the lead screw passes through the drive device mounting plate along the front-back direction and is rotatable relative to the drive device mounting plate around the front-back direction.

[0017] Preferably, the PCR instrument hot cover opening and closing mechanism further includes a reinforcing brace, which is arranged along the left-right direction and located between the front end of the left hot cover plate and the front end of the right hot cover plate, and respectively connects the front end of the left hot cover plate and the front end of the right hot cover plate.

[0018] Preferably, the PCR instrument hot cover opening and closing mechanism further includes a left guide rail, a left slider, a right guide rail, and a right slider. The left and right guide rails are both arranged along the front-back direction and spaced apart from each other, respectively located to the left and right of the lead screw. The rear ends of the left and right guide rails are both located in front of the drive device fixing seat and are both connected to the drive device fixing seat. The front ends of the left and right guide rails are both movably passing through the middle of the intermediate connecting plate along the front-back direction. The left and right sliders are both located in front of the middle of the intermediate connecting plate and are both connected to the middle of the intermediate connecting plate, and are movably arranged on the front ends of the left and right guide rails, respectively.

[0019] Preferably, the camera support bracket is Shaped support frame, the The support frame includes a vertical support plate and a horizontal support plate, both of which are arranged along the front-to-back direction. The lower end of the vertical support plate is disposed on the base plate, and the right end of the horizontal support plate is disposed on the upper end of the vertical support plate. The camera recognition mechanism also includes a connecting plate, which is horizontally arranged along the left-to-right direction. The right end of the connecting plate is disposed on the left end of the horizontal support plate, and the upper end of the camera mounting plate is connected to the left end of the connecting plate.

[0020] Preferably, the camera recognition mechanism further includes a fixing bolt and a fixing nut. The fixing bolt is arranged along the left-right direction, with its right end located on the right side of the camera mounting plate and abutting against the camera mounting plate. The middle part of the fixing bolt passes through the camera mounting plate and the camera mounting plate along the left-right direction. The left end of the fixing bolt is located on the left side of the camera mounting plate. The fixing nut is fitted onto and threadedly engages with the left end of the fixing bolt. The fixing nut is located on the left side of the camera mounting plate and abuts against the camera mounting plate.

[0021] The main beneficial effects of this utility model are as follows:

[0022] 1. The auxiliary button and cover opening / closing device of this utility model, which enables automatic operation of a nucleic acid amplification instrument, utilizes a lead screw drive mechanism to rotate in a forward-backward direction. This causes the intermediate connecting plate to move back and forth relative to the lead screw, thereby moving the left and right hot cover plates back and forth, and ultimately moving the hot cover of the PCR instrument back and forth to open and close the hot cover. A lateral movement drive mechanism drives the longitudinal movement base plate to move left and right, causing the elastic button head to move left and right. A longitudinal movement drive mechanism also drives the button head extension / retraction device to move along the inclined direction of the longitudinal movement guide rail, causing the elastic button head to move along the inclined direction of the longitudinal movement guide rail. The extension / retraction of the button head allows the elastic button head to press the button to be pressed, performing a simulated button action. The information displayed on the camera panel is captured by the camera, and the correctness of the button operation is determined based on the information displayed on the screen. Therefore, it is compatible with existing nucleic acid amplification instruments, enabling automatic cover opening and closing and auxiliary button operation. This facilitates its use in conjunction with fully automated biochemical experimental equipment, significantly reducing laboratory costs and promoting the widespread application of fully automated biochemical experimental equipment. It is suitable for large-scale application.

[0023] 2. When using the auxiliary button and cover opening / closing device for automatic operation of the nucleic acid amplification instrument, the lead screw can be driven to rotate in the front-to-back direction via a lead screw drive device, causing the intermediate connecting plate to move back and forth relative to the lead screw, which in turn moves the left and right hot cover clamping plates back and forth, thereby moving the hot cover of the PCR instrument back and forth to achieve the opening and closing of the hot cover. The lateral movement drive device can drive the longitudinal movement base plate to move left and right, causing the elastic button head to move left and right. The longitudinal movement drive device can drive the button head telescopic device to move along the inclined direction of the longitudinal movement guide rail, causing the elastic button head to move along the inclined direction of the longitudinal movement guide rail. The telescopic device of the button head extends and retracts, causing the elastic button head to press the button to be pressed, performing a simulated button action. The information displayed on the display screen of the camera panel is captured by the camera, and the correctness of the button operation is determined based on the information displayed on the display screen. Therefore, its design is ingenious, its structure is simple, its manufacturing is easy, its manufacturing cost is low, and it is suitable for large-scale promotion and application.

[0024] These and other objects, features and advantages of this utility model will be fully apparent from the following detailed description and drawings, and can be achieved by the means, devices and combinations thereof specifically pointed out in the description of the utility model. Attached Figure Description

[0025] Figure 1 This is a three-dimensional schematic diagram of a specific embodiment of the auxiliary buttons and switch cover device of this utility model that enables automatic operation of a nucleic acid amplification instrument.

[0026] Figure 2 yes Figure 1 A three-dimensional schematic diagram of the auxiliary button mechanism of a specific embodiment is shown.

[0027] Figure 3 yes Figure 1 The diagram shows a partial three-dimensional representation of the structure, which mainly shows the PCR instrument's hot-cover switching mechanism.

[0028] Figure 4 yes Figure 1 A three-dimensional schematic diagram of the camera recognition mechanism in a specific embodiment is shown.

[0029] (Symbol Explanation)

[0030] 1. Base plate;

[0031] 2. Auxiliary button mechanism; 21. Left support; 22. Right support; 23. Lateral moving base plate; 24. Lateral moving guide rail; 25. Lateral moving drive device; 251. Lateral moving driven wheel; 252. Lateral moving driving wheel; 253. Lateral moving synchronous belt; 254. Lateral moving drive component; 255. Lateral moving slider; 26. Longitudinal moving base plate; 27. Longitudinal moving guide rail; 28. Longitudinal moving drive device; 281. Longitudinal moving driven wheel; 282. Longitudinal moving driving wheel; 283. Longitudinal moving synchronous belt; 284. Longitudinal moving drive component; 285. Longitudinal moving slider; 29. ​​Button head telescopic device; 30. Elastic button head;

[0032] 3PCR instrument hot cover opening and closing mechanism; 301 Hot cover left locking plate; 302 Hot cover right locking plate; 303 Intermediate connecting plate; 304 Lead screw; 305 Lead screw drive device; 306 Drive device fixing seat; 307 Right hot cover slot; 308 Drive device fixing plate; 309 Fixing plate connector; 310 Reinforcing rib; 311 Left guide rail; 312 Left slider; 313 Right guide rail; 314 Right slider;

[0033] 4. Camera recognition mechanism; 41. Camera; 42. Camera support frame; 43. Camera mounting plate; 44. Camera fixing plate; 45. Vertical support plate; 46. Horizontal support plate; 47. Connecting plate;

[0034] 5PCR instrument; 51 panel; 52 button area; 53 display screen; 54 heated cover; 55 body. Detailed Implementation

[0035] In order to better understand the technical content of this utility model, the following embodiments are provided for detailed description.

[0036] In the description of this utility model, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0037] Please see Figures 1-4 As shown, in a specific embodiment of this utility model, the auxiliary button and switch cover device for automatic operation of a nucleic acid amplification instrument includes a base plate 1, an auxiliary button mechanism 2, a PCR instrument hot cover switch cover mechanism 3, and a camera recognition mechanism 4, wherein:

[0038] The base plate 1 is horizontally arranged along the front-to-back direction and is used to support the PCR instrument 5 on it;

[0039] The auxiliary button mechanism 2 includes a left support 21, a right support 22, a transverse moving base plate 23, a transverse moving guide rail 24, a transverse moving drive device 25, a longitudinal moving base plate 26, a longitudinal moving guide rail 27, a longitudinal moving drive device 28, a button head telescopic device 29, and a flexible button head 30. The left support 21 and the right support 22 are spaced apart on the base plate 1 and are positioned on the left and right sides of the PCR instrument 5. The transverse moving base plate 23 is arranged in the left-right direction and tilted upwards and backwards in the front-to-back direction. The transverse moving base plate 23 is positioned above and behind the panel 51 of the PCR instrument 5. Its left and right ends are respectively mounted on the left support 21 and the right support 22. The transverse moving guide rail 24 is positioned along the left-right direction and along the inclined direction of the transverse moving base plate 23. The longitudinal moving base plate 26 is positioned along the left-right direction and inclined upwards and backwards from front to back. The longitudinal moving base plate 26 is positioned above and parallel to the panel 51. The rear end of the longitudinal moving base plate 26 is movably mounted on the transverse moving guide rail 24. The transverse moving drive device 25 is mounted on the transverse moving base plate 23 and connected to the rear end of the longitudinal moving base plate 26 to drive the longitudinal moving base plate 26 to move left and right. The longitudinal moving guide rail 27 is mounted along the left and right direction and along the inclined direction of the longitudinal moving base plate 26. The elastic button head 30 is located on the right side of the longitudinal moving base plate 26 and is perpendicular to the longitudinal moving base plate 26 and is used to face the button area 52 of the panel 51. The button head telescopic device 29 is movably mounted on the longitudinal moving guide rail 27 along the inclined direction of the longitudinal moving guide rail 27 and connected to the elastic button head 30 to extend and retract the elastic button head 30 in a direction perpendicular to the longitudinal moving base plate 26. The longitudinal moving drive device 28 is mounted on the longitudinal moving base plate 26 and connected to the button head telescopic device 29 to drive the button head telescopic device 29 to move along the inclined direction of the longitudinal moving guide rail 27.

[0040] The PCR instrument's hot cover opening and closing mechanism 3 includes a left hot cover locking plate 301, a right hot cover locking plate 302, a middle connecting plate 303, a lead screw 304, a lead screw driving device 305, and a driving device fixing seat 306. The left hot cover locking plate 301 and the right hot cover locking plate 302 are both vertically arranged and along the front-back direction, and are spaced apart from each other. The bottom of the left hot cover locking plate 301 and the bottom of the right hot cover locking plate 302 are respectively provided with a left hot cover slot (not shown in the figure) and a right hot cover slot 307 along the left-right direction. The left hot cover slot and the right hot cover slot 307 are spaced apart from each other and are both used to lock onto the hot cover 54 of the PCR instrument 5. The middle connecting plate 303 is vertically arranged and along the left-right direction. The left and right ends of the intermediate connecting plate 303 are located after the rear end of the left heat cover plate 301 and the rear end of the right heat cover plate 302, respectively, and are connected to the rear end of the left heat cover plate 301 and the rear end of the right heat cover plate 302, respectively. The lead screw 304 is arranged along the front-back direction. The front end of the lead screw 304 passes through the middle of the intermediate connecting plate 303 along the front-back direction and is threaded into the middle part of the intermediate connecting plate 303. The drive device fixing seat 306 is located after the intermediate connecting plate 303 and is used to be located after the PCR instrument 5 and installed on the body 55 of the PCR instrument 5. The lead screw drive device 305 is installed on the drive device fixing seat 306 and connected to the rear end of the lead screw 304 to drive the lead screw 304 to rotate around the front-back direction.

[0041] The camera identification mechanism 4 includes a camera 41, a camera support frame 42, a camera mounting plate 43, and a camera fixing plate 44. The camera support frame 42 is disposed on the base plate 1 and is positioned in front of the right side of the PCR instrument 5. The camera fixing plate 44 and the camera mounting plate 43 are both vertically arranged and arranged along the front-back direction, and are mutually abutting each other. The camera mounting plate 43 is located to the left of the camera support frame 42 and is connected to the camera support frame 42. The camera fixing plate 44 is connected to the camera mounting plate 43 and is adjustable in angle relative to the camera mounting plate 43 in the left-right direction. The camera 41 is located to the left of the camera fixing plate 44 and is mounted on the camera fixing plate 44 (e.g., by bolts and nuts) and is used to face the display screen 53 of the panel 51.

[0042] The left support 21 and the right support 22 can have any suitable shape, please refer to Figures 1-2 As shown, in a specific embodiment of this utility model, the left support 21 and the right support 22 are respectively a left support plate and a right support plate, and both the left support plate and the right support plate are vertically arranged and are arranged along the front-back direction.

[0043] The lateral movement drive device 25 can have any suitable configuration; please refer to [link / reference]. Figures 1-2 As shown, in a specific embodiment of this utility model, the lateral movement drive device 25 includes a lateral movement driven wheel 251, a lateral movement driving wheel 252, a lateral movement synchronous belt 253, a lateral movement drive component 254, and a lateral movement slider 255. The lateral movement driven wheel 251 and the lateral movement driving wheel 252 are both parallel to the lateral movement base plate 23 and spaced apart from each other on the left and right sides. Both are rotatably mounted on the lateral movement base plate 23 in a direction perpendicular to the lateral movement base plate 23. The lateral movement drive component 254 is mounted on the lateral movement base plate 23 and connected to the lateral movement driving wheel 252 to drive the lateral movement driving wheel 255. The moving wheel 252 rotates about a direction perpendicular to the transverse moving base plate 23. The transverse moving slider 255 is movably mounted on the transverse moving guide rail 24. The rear end of the longitudinal moving base plate 26 is mounted on the transverse moving slider 255. The transverse moving synchronous belt 253 is mounted along the left-right direction and along the inclined direction of the transverse moving base plate 23 and is located behind the transverse moving guide rail 24. The left and right ends of the transverse moving synchronous belt 253 are respectively sleeved on the transverse moving driven wheel 251 and the transverse moving driving wheel 252. The front belt portion of the transverse moving synchronous belt 253 is connected to the transverse moving slider 255.

[0044] With the above configuration, when the longitudinal moving base plate 26 needs to be moved left and right by the lateral moving drive device 25, the lateral moving drive component 254 drives the lateral moving drive wheel 252 to rotate around a direction perpendicular to the lateral moving base plate 23, thereby driving the lateral moving synchronous belt 253 to rotate around a direction perpendicular to the lateral moving base plate 23, which in turn drives the lateral moving slider 255 to move left and right, thereby driving the longitudinal moving base plate 26 to move left and right.

[0045] The lateral movement drive component 254 can be any suitable drive component. In a specific embodiment of this utility model, the lateral movement drive component 254 is a rotary motor.

[0046] The longitudinal movement drive device 28 can have any suitable configuration; please refer to [link / reference]. Figures 1-2As shown, in a specific embodiment of this utility model, the longitudinal movement drive device 28 includes a longitudinal movement driven wheel 281, a longitudinal movement driving wheel 282, a longitudinal movement synchronous belt 283, a longitudinal movement drive component 284, and a longitudinal movement slider 285. The longitudinal movement driven wheel 281 and the longitudinal movement driving wheel 282 are both parallel to the longitudinal movement base plate 26 and are spaced apart from each other along the inclination direction of the longitudinal movement base plate 26. They are both rotatably mounted on the longitudinal movement base plate 26 about a direction perpendicular to the longitudinal movement base plate 26. The longitudinal movement drive component 284 is mounted on the longitudinal movement base plate 26 and connected to the longitudinal movement driving wheel 282 to drive the longitudinal movement. The drive wheel 282 rotates about a direction perpendicular to the longitudinal moving base plate 26. The longitudinal moving slider 285 is movably mounted on the longitudinal moving guide rail 27 along the inclined direction of the longitudinal moving guide rail 27. The button head telescopic device 29 is mounted on the longitudinal moving slider 285. The longitudinal moving synchronous belt 283 is mounted along the left-right direction and along the inclined direction of the longitudinal moving base plate 26 and is located on the left side of the longitudinal moving guide rail 27. The front end and rear end of the longitudinal moving synchronous belt 283 are respectively sleeved on the longitudinal moving driven wheel 281 and the longitudinal moving drive wheel 282. The right side of the longitudinal moving synchronous belt 283 is connected to the longitudinal moving slider 285.

[0047] With the above configuration, when the button head telescopic device 29 needs to be moved along the inclined direction of the longitudinal moving guide rail 27 by the longitudinal moving drive device 28, the longitudinal moving drive wheel 282 is driven to rotate around a direction perpendicular to the longitudinal moving base plate 26 by the transverse moving drive component 254, which in turn drives the longitudinal moving synchronous belt 283 to rotate around a direction perpendicular to the longitudinal moving base plate 26, thereby driving the longitudinal moving slider 285 to move along the inclined direction of the longitudinal moving guide rail 27, and thus driving the button head telescopic device 29 to move along the inclined direction of the longitudinal moving guide rail 27.

[0048] The longitudinal movement drive component 284 can be any suitable drive component. In a specific embodiment of this utility model, the longitudinal movement drive component 284 is a rotary motor.

[0049] The button head telescopic device 29 can be any suitable telescopic device. In a specific embodiment of this utility model, the button head telescopic device 29 is a push rod motor.

[0050] The elastic button head 30 can be any suitable material. In a specific embodiment of this utility model, the elastic button head 30 is a silicone button head.

[0051] The drive unit mounting base 306 can have any suitable configuration; please refer to [link / reference]. Figure 1 and Figure 3 As shown, in a specific embodiment of this utility model, the drive device fixing base 306 includes a drive device fixing plate 308 and a fixing plate connector 309. The fixing plate connector 309 is located behind and connected to the body 55 of the PCR instrument 5. The drive device fixing plate 308 is vertically arranged and arranged along the left-right direction. The drive device fixing plate 308 is disposed on the fixing plate connector 309 and located behind the intermediate connecting plate 303. The lead screw drive device 305 is located behind the drive device fixing plate 308 and installed on the drive device fixing plate 308. The rear end of the lead screw 304 passes through the drive device fixing plate 308 along the front-back direction and is rotatably arranged relative to the drive device fixing plate 308 around the front-back direction.

[0052] The PCR instrument's hot-lid opening and closing mechanism 3 can also include any other suitable components; please refer to [link / reference needed]. Figure 1 and Figure 3 As shown, in a specific embodiment of this utility model, the PCR instrument hot cover switch mechanism 3 further includes a reinforcing rib 310. The reinforcing rib 310 is arranged along the left-right direction and located between the front end of the left hot cover plate 301 and the front end of the right hot cover plate 302, and is respectively connected to the front end of the left hot cover plate 301 and the front end of the right hot cover plate 302.

[0053] The PCR instrument's hot-lid opening and closing mechanism 3 can also include any other suitable components; please refer to [link / reference needed]. Figure 1 and Figure 3As shown, in a specific embodiment of this utility model, the PCR instrument hot cover switching mechanism 3 further includes a left guide rail 311, a left slider 312, a right guide rail 313, and a right slider 314. The left guide rail 311 and the right guide rail 313 are both arranged along the front-back direction and spaced apart from each other, respectively located on the left and right sides of the lead screw 304. The rear ends of the left guide rail 311 and the right guide rail 313 are both located in front of the drive device fixing seat 306 and are both connected to the drive device fixing seat 306. The front ends of the left guide rail 311 and the right guide rail 313 are both movably passing through the middle of the intermediate connecting plate 303 along the front-back direction. The left slider 312 and the right slider 314 are both located in front of the middle of the intermediate connecting plate 303 and are both connected to the middle of the intermediate connecting plate 303, and are respectively movably arranged on the front ends of the left guide rail 311 and the right guide rail 313. With the above configuration, the left guide rail 311, the left slider 312, the right guide rail 313, and the right slider 314 achieve forward and backward guiding. When the drive device mounting base 306 includes a drive device mounting plate 308 and a mounting plate connector 309, the rear ends of the left guide rail 311 and the right guide rail 313 are both located in front of and connected to the drive device mounting plate 308.

[0054] The lead screw drive device 305 can be any suitable drive device. In a specific embodiment of this utility model, the lead screw drive device 305 is a rotary motor.

[0055] The camera support bracket 42 can have any suitable shape; please refer to [link / reference]. Figure 1 and Figure 4 As shown, in a specific embodiment of this utility model, the camera support frame 42 is... Shaped support frame, the The support frame includes a vertical support plate 45 and a horizontal support plate 46, both of which are arranged along the front-to-back direction. The lower end of the vertical support plate 45 is located on the base plate 1, and the right end of the horizontal support plate 46 is located on the upper end of the vertical support plate 45. The camera recognition mechanism 4 also includes a connecting plate 47, which is arranged horizontally along the left-to-right direction. The right end of the connecting plate 47 is located (e.g., fixed to) the left end of the horizontal support plate 46 by bolts and nuts. The upper end of the camera mounting plate 43 is connected to the left end of the connecting plate 47.

[0056] The camera mounting plate 44 is connected to the camera mounting plate 43 and its rotation angle relative to the camera mounting plate 43 in the left-right direction is adjustable. It can adopt any suitable structure. In a specific embodiment of this utility model, the camera recognition mechanism 4 further includes a fixing bolt and a fixing nut. The fixing bolt is arranged along the left-right direction. The right end of the fixing bolt is located on the right side of the camera mounting plate 43 and abuts against the camera mounting plate 43. The middle part of the fixing bolt passes through the camera mounting plate 43 and the camera mounting plate 44 along the left-right direction. The left end of the fixing bolt is located on the left side of the camera mounting plate 44. The fixing nut is sleeved on and threadedly engaged with the left end of the fixing bolt. The fixing nut is located on the left side of the camera mounting plate 44 and abuts against the camera mounting plate 44.

[0057] With the above settings, when it is necessary to adjust the rotation angle of the camera mounting plate 44 relative to the camera mounting plate 43 in the left and right directions, loosen the fixing nut, and then rotate the camera mounting plate 44 relative to the camera mounting plate 43 in the left and right directions to the desired position, and tighten the fixing nut, thereby realizing the adjustment of the rotation angle of the camera mounting plate 44 relative to the camera mounting plate 43 in the left and right directions.

[0058] In use, place the PCR instrument 5 in a suitable position on the base plate 1. Place the left support 21 and right support 22 on the left and right sides of the PCR instrument 5, respectively, and fix them (e.g., with bolts) on the base plate 1. Position the lateral moving base plate 23 above the rear side of the panel 51 of the PCR instrument 5, and the longitudinal moving base plate 26 above and parallel to the panel 51. Position the elastic button head 30 towards the button area 52 of the panel 51. Place the left and right hot cover retaining plates 301 and 302 above the hot cover 54 of the PCR instrument 5, ensuring the left and right hot cover retaining slots are aligned. Align 307 with the hot cover 54 of the PCR instrument 5, then lower the left hot cover retainer 301 and the right hot cover retainer 302 so that the left hot cover retainer slot and the right hot cover retainer slot 307 are engaged on the hot cover 54 of the PCR instrument 5. Install the drive device mounting base 306 (e.g., by screws) on the body 55 of the PCR instrument 5. Place the camera support bracket 42 on the right front of the PCR instrument 5 and set it on the base plate 1 (e.g., by bolts). Adjust the rotation angle of the camera mounting plate 44 relative to the camera mounting plate 43 in the left and right directions so that the camera 41 faces the display screen 53 of the panel 51.

[0059] During operation, the lead screw drive device 305 can drive the lead screw 304 to rotate in the front-back direction, causing the intermediate connecting plate 303 to move backward relative to the lead screw 304. This moves the left and right hot cover retaining plates 301 and 302 backward, thereby moving the hot cover 54 of the PCR instrument 5 backward and opening the hot cover 54. At this time, it can be used in conjunction with a robotic arm, such as that of a fully automated biochemical experimental device, to place or remove PCR plates into or from the PCR instrument 5. Then, the lead screw drive device 305 can drive the lead screw 304 to rotate in the opposite direction, causing the intermediate connecting plate 303 to move forward relative to the lead screw 304. This moves the left and right hot cover retaining plates 301 and 302 forward, thereby moving the hot cover 54 of the PCR instrument 5 forward and closing the hot cover 54. This back-and-forth sliding opening and closing method of the hot cover 54 is suitable for a type of amplification equipment, represented by the AB 9700 amplification instrument.

[0060] The lateral movement drive 25 can drive the longitudinal movement base plate 26 to move left and right, thereby driving the longitudinal movement guide rail 27 and the button head telescopic device 29 to move left and right, thus driving the elastic button head 30 to move left and right; the longitudinal movement drive 28 can drive the button head telescopic device 29 to move along the inclined direction of the longitudinal movement guide rail 27, thereby driving the elastic button head 30 to move along the inclined direction of the longitudinal movement guide rail 27; thus, through the lateral movement drive 25 and the longitudinal movement drive 28, the elastic button head 30 can be moved toward any button to be pressed, and then the button head telescopic device 29 can be extended to move the elastic button head 30 toward the button to be pressed until the button to be pressed is pressed. After pressing, the button head telescopic device 29 can be shortened to move the elastic button head 30 away from the button to be pressed, thereby performing a simulated button action;

[0061] After the button press is performed, the camera 41 captures the information displayed on the display screen 53 of the panel 51. The information displayed on the display screen 53 is used to determine whether the button press operation was completed correctly. If it was not completed correctly, the above process can be repeated.

[0062] This invention can be integrated into a fully automated biochemical experimental device. The device issues relevant control commands; for example, when a command to open / close the heated cover 54 is issued, the lead screw drive 305 is activated to perform the opening / closing action. When a button operation command is issued, the horizontal movement drive 25 and the vertical movement drive 28 are activated, moving the elastic button head 30 above the desired button. Then, the button head extension device 29 extends, causing the elastic button head 30 to perform a vertical downward pressing action relative to the button. After the button operation is completed, the camera 41 captures the information displayed on the screen 53 of the panel 51. Based on the information displayed on the screen 53, it is determined whether the button operation was completed correctly, and other button operations can be performed according to subsequent commands. In this way, the operation of the PCR instrument 5 can be automatically completed under the control of the fully automated biochemical experimental device, achieving fully automated adaptation.

[0063] Therefore, this utility model provides an auxiliary button and cover switch device for automatic operation of a nucleic acid amplification instrument. The PCR instrument's hot cover can be switched on and off via the hot cover switch mechanism, and the auxiliary button mechanism enables the button operation on the PCR instrument's panel. The camera recognition mechanism can determine whether the button operation was completed correctly. This allows the existing PCR instrument operated manually to be used in conjunction with fully automated biochemical experimental equipment, thereby greatly saving laboratory costs and promoting the widespread use of fully automated biochemical experimental equipment.

[0064] In summary, the auxiliary buttons and cover opening / closing device of this utility model, which enable automatic operation of nucleic acid amplification instruments, are compatible with existing nucleic acid amplification instruments, enabling automatic cover opening and closing and auxiliary button operation. This allows for use in conjunction with fully automated biochemical experimental equipment, thereby significantly reducing laboratory costs and facilitating the widespread use of fully automated biochemical experimental equipment. The design is ingenious, the structure is simple, the manufacturing process is easy, and the manufacturing cost is low, making it suitable for large-scale promotion and application.

[0065] Therefore, it is evident that the objective of this utility model has been fully and effectively achieved. The function and structural principles of this utility model have been demonstrated and explained in the embodiments. Without departing from the stated principles, any modifications can be made to the implementation methods. Therefore, this utility model includes all modified embodiments based on the spirit and scope of the claims.

Claims

1. An auxiliary button and switch cover device for automating the operation of a nucleic acid amplification instrument, characterized in that, This includes a base plate, auxiliary button mechanism, PCR instrument hot-cover opening and closing mechanism, and camera recognition mechanism, among which: The base plate is horizontally positioned along the front-to-back direction and is used to support the PCR instrument. The auxiliary button mechanism includes a left support, a right support, a transverse moving base plate, a transverse moving guide rail, a transverse moving drive device, a longitudinal moving base plate, a longitudinal moving guide rail, a longitudinal moving drive device, a button head telescopic device, and a flexible button head. The left and right supports are spaced apart on the base plate and positioned on the left and right sides of the PCR instrument. The transverse moving base plate is positioned along the left-right direction and inclined upwards and backwards, positioned above the rear side of the PCR instrument's panel. The left and right ends of the transverse moving base plate are respectively mounted on the left and right supports. The transverse moving guide rail is positioned along the left-right direction and along the inclined direction of the transverse moving base plate. The longitudinal moving base plate is positioned along the left-right direction and inclined upwards and backwards, positioned above the panel and parallel to the panel. The rear end of the longitudinally moving base plate is movably mounted on the transversely moving guide rail. The transversely moving drive device is mounted on the transversely moving base plate and connected to the rear end of the longitudinally moving base plate to drive the longitudinally moving base plate to move left and right. The longitudinally moving guide rail is arranged along the left-right direction and along the inclined direction of the longitudinally moving base plate. The elastic button head is located on the right side of the longitudinally moving base plate and is perpendicular to the longitudinally moving base plate and is used to face the button area of ​​the panel. The button head telescopic device is movably mounted on the longitudinally moving guide rail along the inclined direction of the longitudinally moving guide rail and connected to the elastic button head to extend and retract the elastic button head in a direction perpendicular to the longitudinally moving base plate. The longitudinally moving drive device is mounted on the longitudinally moving base plate and connected to the button head telescopic device to drive the button head telescopic device to move along the inclined direction of the longitudinally moving guide rail. The PCR instrument's hot cover opening and closing mechanism includes a left hot cover locking plate, a right hot cover locking plate, a middle connecting plate, a lead screw, a lead screw drive device, and a drive device fixing base. Both the left and right hot cover locking plates are vertically arranged and aligned along the front-to-back direction, spaced apart from each other. The bottom of the left and right hot cover locking plates each have a left hot cover slot and a right hot cover slot, respectively, arranged along the left-to-right direction. These slots are spaced apart and both are used to engage with the hot cover of the PCR instrument. The middle connecting plate is vertically arranged and aligned along the left-to-right direction. The left and right ends of the connecting plate are located behind the rear ends of the left and right heat cover plates, respectively, and are connected to the rear ends of the left and right heat cover plates, respectively. The lead screw is arranged along the front-back direction, and the front end of the lead screw passes through and threadedly engages the middle part of the intermediate connecting plate along the front-back direction. The drive device mounting base is located behind the intermediate connecting plate and is used to be located behind the PCR instrument and installed on the body of the PCR instrument. The lead screw drive device is installed on the drive device mounting base and connected to the rear end of the lead screw for driving the lead screw to rotate around the front-back direction. The camera identification mechanism includes a camera, a camera support frame, a camera mounting plate, and a camera fixing plate. The camera support frame is mounted on the base plate and positioned in front of the right side of the PCR instrument. The camera fixing plate and the camera mounting plate are both vertically arranged and along the front-back direction, and are mutually abutting each other. The camera mounting plate is located to the left of the camera support frame and is connected to the camera support frame. The camera fixing plate is connected to the camera mounting plate and is adjustable in angle relative to the camera mounting plate in the left-right direction. The camera is located to the left of the camera fixing plate and is mounted on the camera fixing plate, facing the display screen of the panel.

2. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The left support and the right support are respectively a left support plate and a right support plate, both of which are vertically arranged and arranged along the front-back direction.

3. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The lateral movement drive device includes a lateral movement driven wheel, a lateral movement driving wheel, a lateral movement timing belt, a lateral movement drive component, and a lateral movement slider. The lateral movement driven wheel and the lateral movement driving wheel are both parallel to the lateral movement base plate and spaced apart from each other on the left and right sides. Both are rotatably mounted on the lateral movement base plate in a direction perpendicular to the lateral movement base plate. The lateral movement drive component is mounted on the lateral movement base plate and connected to the lateral movement driving wheel to drive the lateral movement driving wheel to rotate in a direction perpendicular to the lateral movement base plate. The lateral movement slider is movably mounted on the lateral movement guide rail on the left and right sides. The rear end of the longitudinal movement base plate is mounted on the lateral movement slider. The lateral movement timing belt is positioned along the left and right directions and along the inclined direction of the lateral movement base plate, located behind the lateral movement guide rail. The left and right ends of the lateral movement timing belt are respectively sleeved on the lateral movement driven wheel and the lateral movement driving wheel. The front portion of the lateral movement timing belt is connected to the lateral movement slider.

4. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The longitudinal movement drive device includes a longitudinal movement driven wheel, a longitudinal movement driving wheel, a longitudinal movement timing belt, a longitudinal movement drive component, and a longitudinal movement slider. The longitudinal movement driven wheel and the longitudinal movement driving wheel are both parallel to the longitudinal movement base plate and are spaced apart from each other along the inclined direction of the longitudinal movement base plate. Both are rotatably mounted on the longitudinal movement base plate in a direction perpendicular to the longitudinal movement base plate. The longitudinal movement drive component is mounted on the longitudinal movement base plate and connected to the longitudinal movement driving wheel to drive the longitudinal movement driving wheel to rotate in a direction perpendicular to the longitudinal movement base plate. The longitudinal movement slider is movably mounted on the longitudinal movement guide rail along the inclined direction of the longitudinal movement guide rail. The button head telescopic device is mounted on the longitudinal movement slider. The longitudinal movement timing belt is positioned along the left-right direction and along the inclined direction of the longitudinal movement base plate, located on the left side of the longitudinal movement guide rail. The front and rear ends of the longitudinal movement timing belt are respectively sleeved on the longitudinal movement driven wheel and the longitudinal movement driving wheel. The right side of the longitudinal movement timing belt is connected to the longitudinal movement slider.

5. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The button head telescopic device is a push rod motor.

6. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The drive device mounting base includes a drive device mounting plate and a mounting plate connector. The mounting plate connector is located behind and connected to the body of the PCR instrument. The drive device mounting plate is vertically arranged along the left-right direction. The drive device mounting plate is mounted on the mounting plate connector and located behind the intermediate connecting plate. The lead screw drive device is located behind the drive device mounting plate and mounted on the drive device mounting plate. The rear end of the lead screw passes through the drive device mounting plate along the front-back direction and is rotatable relative to the drive device mounting plate around the front-back direction.

7. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The PCR instrument's hot cover opening and closing mechanism also includes a reinforcing brace. The reinforcing brace is arranged along the left-right direction and is located between the front end of the left hot cover plate and the front end of the right hot cover plate, respectively connecting the front end of the left hot cover plate and the front end of the right hot cover plate.

8. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The PCR instrument's hot-cover opening and closing mechanism further includes a left guide rail, a left slider, a right guide rail, and a right slider. The left and right guide rails are both arranged along the front-back direction and spaced apart from each other, respectively located to the left and right of the lead screw. The rear ends of the left and right guide rails are both located in front of the drive device mounting base and are both connected to the drive device mounting base. The front ends of the left and right guide rails are both movably passing through the middle of the intermediate connecting plate along the front-back direction. The left and right sliders are both located in front of the middle of the intermediate connecting plate and are both connected to the middle of the intermediate connecting plate, and are movably arranged on the front ends of the left and right guide rails, respectively.

9. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The camera support frame is Shaped support frame, the The support frame includes a vertical support plate and a horizontal support plate, both of which are arranged along the front-to-back direction. The lower end of the vertical support plate is disposed on the base plate, and the right end of the horizontal support plate is disposed on the upper end of the vertical support plate. The camera recognition mechanism also includes a connecting plate, which is horizontally arranged along the left-to-right direction. The right end of the connecting plate is disposed on the left end of the horizontal support plate, and the upper end of the camera mounting plate is connected to the left end of the connecting plate.

10. The auxiliary key and switch cover apparatus for enabling automated operation of a nucleic acid amplification instrument of claim 1, wherein, The camera recognition mechanism further includes a fixing bolt and a fixing nut. The fixing bolt is arranged along the left-right direction. The right end of the fixing bolt is located on the right side of the camera mounting plate and abuts against the camera mounting plate. The middle part of the fixing bolt passes through the camera mounting plate and the camera mounting plate along the left-right direction. The left end of the fixing bolt is located on the left side of the camera mounting plate. The fixing nut is sleeved on and threadedly engaged with the left end of the fixing bolt. The fixing nut is located on the left side of the camera mounting plate and abuts against the camera mounting plate.

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