Sample cryopreservation box and refrigeration sample storage system

Abstract

The utility model discloses a sample cryopreservation box which comprises a box body and a box cover which are assembled in a fan-shaped structure in a matched mode, a plurality of rows of placing holes are formed in the upper side in the box body in a concave mode, a placing groove is formed in the periphery of the box body, a box outer wall is arranged on the periphery of the box cover, and the box outer wall is matched with the placing groove to achieve tight assembly of the box body and the box cover. Through the design of the sample cryopreservation box, the arrangement relation between the layout of the multiple rows of imbedding holes and the fan-shaped box body realizes high efficiency and convenience of sample storage through geometric optimization and functional design. The arc-shaped boundary of the fan-shaped box body provides a natural curve boundary for the arrangement of the imbedding holes, and the arrangement of the holes is regular and compact due to the multi-row side-by-side arrangement mode. The suitability and the stability of the sample box are further improved through the optimal design of the hole diameter, the hole distance, the depth and the inclination angle, so that the sample box can adapt to test tubes of various specifications, and meanwhile, the safety of samples in the storage and transportation process is ensured; and the application requirements of high-density storage and convenient access in the subsequent cold storage sample storage device are met.

Description

Technical Field

[0001] This utility model relates to the field of biotechnology, specifically to a sample cryopreservation box and refrigerated sample storage system for the cryopreservation of biological samples. Background Technology

[0002] In the biomedical field, sample cryopreservation equipment is used to store biological samples such as blood samples, vaccines, and bacterial / viral strains at low temperatures, keeping the samples in liquid nitrogen for long-term viability preservation. The equipment contains multiple sample boxes, each containing multiple test tubes; the sample to be stored is contained within one of these test tubes.

[0003] Typically, a large number of samples need to be stored in multiple storage devices, requiring manual intervention to connect to these devices. This can easily lead to cell contamination issues caused by manual operation, and the storage capacity is relatively small, resulting in low access efficiency. Utility Model Content

[0004] The purpose of this invention is to overcome the shortcomings of the existing technology and provide a sample cryopreservation box and a cold storage system.

[0005] The sample cryopreservation box includes a box body and a box lid that are assembled in a fan-shaped structure. The upper side of the inside of the box body is recessed to form several rows of insertion holes. An insertion groove is formed on the outer periphery of the box body. An outer wall is provided on the outer periphery of the box lid. The outer wall of the box and the insertion groove cooperate to achieve a tight assembly of the box body and the box lid.

[0006] Furthermore, each of the insertion holes is arranged in multiple rows side by side within the fan-shaped box, with each row of insertion holes extending along the radius of the fan shape to form a radial layout.

[0007] Furthermore, each of the insertion holes is circular, and in each row of insertion holes, the insertion holes are connected by a transverse channel.

[0008] Furthermore, the arrangement of each insertion hole is based on the center point of the fan-shaped box and is evenly distributed along the radial direction to form a centrally symmetrical layout.

[0009] Furthermore, the insertion groove is arranged in a fan shape around the outer periphery of each row of insertion holes, and the insertion groove forms an upward protrusion on the arc-shaped side of the box body; the box cover has a recessed section on its arc-shaped side in accordance with the protrusion.

[0010] Furthermore, the lower side of the arc-shaped section of the lid is provided with a gripping groove for grasping and holding; and / or, the lower side of the arc-shaped section of the box body is provided with a positioning groove for placement and positioning.

[0011] A refrigerated sample storage system includes a refrigerated compartment, which is cylindrical in shape and has a temperature control and refrigeration device in the center. Multiple sample storage racks are evenly distributed around the outer periphery of the refrigerated compartment, and the sample storage racks are arranged in a ring. Sample cryopreservation boxes as described above are positioned and mounted on the sample storage racks.

[0012] Furthermore, the cold storage compartment has an opening on its upper side, and a cover can be installed at the opening; the cover is based on a lifting and rotating mechanism to enable the cold storage compartment opening to be exposed and closed.

[0013] Furthermore, a robotic arm device is provided on the side of the upper opening of the cold storage compartment, and the control end of the robotic arm device has a grasping engagement relationship with the upper end of the sample storage rack; a rotation drive device is provided at the bottom of the cold storage compartment to drive each of the sample storage racks arranged in a ring to rotate horizontally around the axis of the cold storage compartment.

[0014] Furthermore, the sample storage holder includes multiple fan-shaped positioning plates, which are arranged in multiple layers along the vertical direction, and an insertion port for placing the sample cryopreservation box is formed on the outer periphery between each layer of positioning plates.

[0015] The beneficial effects of this utility model are as follows:

[0016] Through geometric optimization and functional design, the multi-row layout of the sample cryopreservation box achieves high efficiency and convenience in sample storage. The curved boundary of the fan-shaped box provides a natural curved boundary for the arrangement of the insertion holes, while the multi-row side-by-side arrangement ensures a regular and compact layout. Optimized design of hole diameter, hole spacing, depth, and tilt angle further improves the adaptability and stability of the sample box, enabling it to accommodate various test tube sizes while ensuring sample safety during storage and transportation; meeting the application requirements for high-density storage and convenient access in subsequent refrigerated sample storage devices. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structural design of the sample cryopreservation box of this utility model.

[0018] Figure 2 This is an exploded view of the sample cryopreservation box of this utility model.

[0019] Figure 3 This is a schematic diagram of the structural setup of the refrigerated sample storage device of this utility model.

[0020] Explanation of reference numerals in the attached figures:

[0021] Box body 1, insertion hole 11, transverse channel 111, insertion groove 12, protruding section 121, positioning groove 13

[0022] 2. Box lid, 21. Box outer wall, 211. Recessed section, 22. Gripping groove.

[0023] Refrigerated compartment 3, temperature control and refrigeration device 31, sample storage rack 32, positioning plate 321, compartment cover 33, lifting and rotating device 331, robotic arm device 34. Detailed Implementation

[0024] To make the technical solution, purpose and advantages of this utility model clearer, the following explanation is given in conjunction with the accompanying drawings and embodiments.

[0025] like Figures 1 to 3 As shown, the refrigerated sample storage system of this utility model includes a frame with a cylindrical refrigerated compartment 3 at its center. The refrigerated compartment 3 has an opening on its upper side. A temperature-controlled refrigeration device 31 is vertically mounted at the center of the refrigerated compartment 3. This temperature-controlled refrigeration device 31 can be a conventional refrigeration module of the prior art. Multiple vertically extending sample storage supports 32 are evenly distributed around the temperature-controlled refrigeration device 31, and the sample storage supports 32 are arranged in a ring around the outer periphery of the refrigerated compartment 3. Sample cryopreservation boxes are placed on the sample storage supports 32 for placing biological samples for cryopreservation within the refrigerated compartment 3.

[0026] Specifically, the sample storage rack 32 includes multiple fan-shaped positioning plates 321. Based on the outer frame structure of the sample storage rack 32, the positioning plates 321 are arranged in multiple layers along the vertical direction, making the sample storage rack 32 as a fan-shaped column. An insertion port for inserting the sample cryopreservation box is formed on the outer periphery between each layer of positioning plates 321, allowing the sample cryopreservation box to be inserted into the sample storage rack 32 from the side through the insertion port. Multiple fan-shaped column-shaped sample storage racks 32 are evenly distributed to form a ring-shaped sample storage rack group 32, and the outer diameter of the sample storage rack group 32 is adapted to the inner diameter of the cold storage compartment 3.

[0027] The upper opening of the cold storage compartment 3 can be covered by a compartment cover 33; the compartment cover 33 is based on the existing lifting drive cylinder and rotating mechanism, which are combined to form a lifting and rotating device 331 to satisfy the lifting and rotating motion mechanism and realize the exposure and closing of the opening of the cold storage compartment 3.

[0028] A robotic arm 34 is installed beside the upper opening of the cold storage compartment 3. The control end of the robotic arm 34 has a gripping relationship with the upper end of the sample storage rack 32. Furthermore, a rotation drive device is installed at the bottom of the cold storage compartment 3 to drive the circularly arranged sample storage racks 32 to rotate horizontally around the axis of the cold storage compartment 3. In application, taking the removal of a sample cryopreservation box as an example, the positioned robotic arm can grasp the corresponding sample storage rack 32 at a fixed position, lift and rotate it to the designated position for the user to place the sample into the cryopreservation box. This rotation drive device can cooperate to drive the sample storage rack 32 containing the target sample cryopreservation box to rotate to the extraction position of the robotic arm 34, facilitating the robotic arm 34 to complete the extraction operation.

[0029] In this invention, in conjunction with the aforementioned refrigerated sample storage system, a fan-shaped sample cryopreservation box design is provided.

[0030] The sample cryopreservation box includes a box body 1 and a box lid 2 assembled in a fan-shaped structure. The upper interior of the box body 1 has recessed upper sections forming several rows of insertion holes 11. These insertion holes 11 are arranged in multiple rows side-by-side within the fan-shaped box body 1, with each row extending radially along the fan shape, forming a radial layout. The arrangement of the insertion holes 11 is based on the center point of the fan shape of the box body 1, and is evenly distributed radially, forming a centrally symmetrical layout. Each insertion hole 11 is circular. Within each row of insertion holes 11, the holes are connected by transverse channels 111. The inner diameter of the transverse channels 111 is smaller than the inner diameter of the insertion holes 11. When multiple insertion holes 11 with transverse channels 111 are connected, it does not affect the stable insertion of test tubes and also facilitates the flow of refrigerated atmosphere.

[0031] The outer periphery of the box body 1 forms an insertion groove 12, and the outer periphery of the box lid 2 is provided with an outer wall 21. The outer wall 21 and the insertion groove 12 cooperate to achieve a tight assembly of the box body 1 and the box lid 2. Specifically, the insertion groove 12 is arranged in a fan shape around the outer periphery of each row of insertion holes 11, and the insertion groove 12 forms an upward protrusion 121 on the arc-shaped side of the box body 1; the box lid 2 has a recessed section 211 on its arc-shaped side in response to the protrusion 121. The lower side of the arc-shaped section of the box lid 2 is provided with a gripping groove 22 for grasping and holding, which meets the user's application needs for grasping and opening the box lid 2; while the lower side of the arc-shaped section of the box body 1 is provided with a positioning groove 13 for placement and positioning.

[0032] Based on the structural design of the insertion slot 12 and the outer wall 21 of the box, the box body 1 and the lid 2 of the sample cryopreservation box can be stably fitted together, and the surrounding space can be fully utilized. The positioning slot 13 is designed to fit the positioning blocks on the positioning plates 321 of each layer of the sample storage rack 32, so that the inserted sample cryopreservation box can be held and positioned on the sample storage rack 32 after being placed on it, ensuring the stable assembly of the sample cryopreservation box on the sample storage rack 32.

[0033] The above description is only a preferred embodiment of the present utility model. For those skilled in the art, modifications can still be made to the embodiments without departing from the implementation principle of the present utility model, and the corresponding modifications should also be considered within the protection scope of the present utility model.

Claims

1. A sample cryopreservation box, characterized in that, The box includes a box body and a box lid that are assembled in a fan-shaped structure. The upper side of the inside of the box body is recessed to form several rows of insertion holes. An insertion groove is formed on the outer periphery of the box body. An outer wall is provided on the outer periphery of the box lid. The outer wall of the box and the insertion groove cooperate to achieve a tight assembly of the box body and the box lid.

2. The sample cryopreservation box according to claim 1, characterized in that, The insertion holes are arranged in multiple rows side by side within the fan-shaped box, with each row of insertion holes extending along the radius of the fan shape to form a radial layout.

3. The sample cryopreservation box according to claim 2, characterized in that, Each of the insertion holes is circular, and the insertion holes in each row are connected by a transverse channel.

4. The sample cryopreservation box according to claim 2, characterized in that, The arrangement of each insertion hole is based on the center point of the fan-shaped box and is evenly distributed along the radial direction to form a centrally symmetrical layout.

5. The sample cryopreservation box according to any one of claims 1 to 4, characterized in that, The insertion groove is arranged in a fan shape around the outer periphery of each row of insertion holes, and the insertion groove forms an upward protrusion on the arc-shaped side of the box body; the box cover has a recessed section on its arc-shaped side in accordance with the protrusion.

6. The sample cryopreservation box according to claim 5, characterized in that, The lower side of the arc-shaped section of the lid is provided with a gripping groove for grasping and holding; and / or, the lower side of the arc-shaped section of the box body is provided with a positioning groove for placement and positioning.

7. A refrigerated sample storage system, characterized in that, The device includes a cold storage compartment, which is cylindrical in shape and has a temperature control and refrigeration device in the center. Multiple sample storage racks are evenly distributed around the outer periphery of the cold storage compartment, and the sample storage racks are arranged in a circular shape. Sample cryopreservation boxes as described in any one of claims 1 to 6 are positioned and assembled on the sample storage racks.

8. The refrigerated sample storage system according to claim 7, characterized in that, The cold storage compartment has an opening on its upper side, and a cover can be installed at the opening; the cover is based on a lifting and rotating mechanism to enable the cold storage compartment opening to be exposed and closed.

9. The refrigerated sample storage system according to claim 8, characterized in that, A robotic arm is installed on the side of the upper opening of the cold storage compartment. The control end of the robotic arm has a gripping relationship with the upper end of the sample storage rack. A rotation drive device is installed at the bottom of the cold storage compartment to drive each of the sample storage racks arranged in a ring to rotate horizontally around the axis of the cold storage compartment.

10. The refrigerated sample storage system according to any one of claims 7 to 9, characterized in that, The sample storage holder includes multiple fan-shaped positioning plates, which are arranged in multiple layers along the vertical direction. An insertion port for inserting the sample cryopreservation box is formed on the outer periphery between each layer of positioning plates.

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