Mounting structure and pipetting device

Abstract

The utility model discloses a mounting structure and discloses a pipetting device with the mounting structure, and the mounting structure comprises a water tank, an experiment tube and a first mounting groove, a liquid inlet hole is formed in the bottom end of the experiment tube, a first magnet is fixedly connected to the bottom surface of the experiment tube, and a first sealing groove is formed in the bottom surface of the experiment tube; the first mounting groove is formed in the bottom of the constant-temperature cavity, a liquid outlet hole penetrates through the bottom of the first mounting groove, a second magnetic block is fixed to the bottom face of the mounting groove, and a second sealing groove is formed in the bottom of the mounting groove; wherein the bottom end of the experimental tube is embedded in the first mounting groove, the liquid outlet hole corresponds to the liquid inlet hole in position, the first magnet is magnetically connected with the second magnet, the first sealing groove corresponds to the second sealing groove in position, and a sealing rubber ring is embedded between the first sealing groove and the second sealing groove. A sealing rubber ring is matched with a detachable magnetic attraction structure, so that the experiment liquid is prevented from leaking, and meanwhile, an experimenter can conveniently and quickly disassemble and assemble the experiment tube.

Description

Technical Field

[0001] This utility model relates to the field of biological experimental technology, and in particular to an installation structure and a pipetting device. Background Technology

[0002] In the field of biomedical experiments, the study of the physiological characteristics of smooth muscle is an important fundamental experimental task, requiring the observation of the effects of physicochemical factors or drugs on smooth muscle contraction using specimens such as isolated intestinal segments. In such experiments, the stability of the experimental apparatus, the precision of fluid manipulation, and the ease of operation directly affect the reliability and efficiency of the experimental results.

[0003] For example, utility model patent application number 202322122033.0 discloses a smooth muscle experimental system capable of precisely controlling preload, relating to the field of biological experimental technology. It includes a shell and an internal operating device. The internal operating device includes a ventilation component, an experimental tube, a tension transducer, an automatic lifting rod, and a control panel. The ventilation component provides gas to the experimental tube. The tension transducer includes a tension transducer and a fixing component. The tension transducer is fixed to the automatic lifting rod via the fixing component. The automatic lifting rod is connected to a motor and controlled by the control panel. In this design, the experimental tube installation method is outdated, often using threaded connections or snap-fit ​​fixation. Installation requires repeated alignment and calibration, which is time-consuming and labor-intensive. Furthermore, the sealing effect is poor, and long-term use can lead to aging and liquid leakage. Utility Model Content

[0004] This invention aims to solve at least one of the technical problems existing in the prior art. To this end, this invention proposes an installation structure that allows for quick assembly and disassembly while ensuring a tight seal.

[0005] This utility model also proposes a pipetting device having the above-described mounting structure.

[0006] According to the first aspect of the present invention, the installation structure includes a water tank, an experimental tube, and a first mounting groove. The water tank is provided with a constant temperature chamber. An inlet hole is provided at the bottom end of the experimental tube, penetrating the bottom surface of the experimental tube. A first magnet is fixedly connected to the bottom surface of the experimental tube, and a first sealing groove is provided on the bottom surface of the experimental tube. The first mounting groove is located at the bottom of the constant temperature chamber, with an outlet hole penetrating through the bottom of the first mounting groove. A second magnetic block is fixed to the bottom surface of the mounting groove, and a second sealing groove is provided at the bottom of the mounting groove. The bottom end of the experimental tube is embedded in the first mounting groove so that the bottom surface of the experimental tube abuts against the bottom surface of the first mounting groove. The outlet hole and the inlet hole are positioned correspondingly, and the first magnet and the second magnetic block are magnetically connected. The first sealing groove and the second sealing groove are positioned correspondingly, and a sealing ring is embedded between the first sealing groove and the second sealing groove.

[0007] The installation structure according to the embodiment of this utility model has at least the following beneficial effects: by using a sealing ring in conjunction with a detachable magnetic structure, it ensures that the experimental liquid will not leak out, while facilitating quick assembly and disassembly of the experimental tube by the experimental personnel.

[0008] According to some embodiments of the present invention, the sealing ring is fixed in the second sealing groove.

[0009] According to some embodiments of the present invention, the second magnetic block is annular, the second sealing groove is annular and located inside the second magnetic block, and the liquid outlet is located inside the second sealing groove, wherein the second magnetic block, the second sealing groove and the liquid outlet are concentric.

[0010] The pipetting device according to a second aspect embodiment of the present invention includes the installation structure described in any of the above embodiments, a liquid storage beaker, a preheating beaker, a waste liquid tank, a venting assembly, and a hanging assembly. The liquid storage beaker is fixed in the constant temperature chamber, and a liquid supply pipe is provided between the liquid storage beaker and the liquid outlet. The liquid supply pipe is equipped with a first liquid pump. The preheating beaker is placed in the constant temperature chamber. The waste liquid tank and the water tank are integrally formed. The waste liquid tank is provided with a waste liquid chamber, and a waste liquid pipe is provided between the waste liquid chamber and the liquid outlet. The waste liquid pipe is equipped with a second liquid pump. The venting assembly is connected to a venting pipe, one end of which extends into the experimental tube. The hanging assembly is installed on the upper surface of the water tank and is used to hang specimens.

[0011] The pipetting device according to the embodiments of this utility model has at least the following beneficial effects: by using a sealing ring in conjunction with a detachable magnetic structure, it ensures that the experimental liquid will not leak out, while facilitating quick assembly and disassembly of the experimental tube by the experimenter.

[0012] According to some embodiments of the present invention, the constant temperature cavity is further provided with a second mounting groove, and the preheating beaker is embedded in the second mounting groove.

[0013] According to some embodiments of this utility model, the liquid outlet is connected to a liquid outlet pipe, and a three-way reversing valve is connected between the liquid outlet pipe, the liquid supply pipe, and the waste liquid pipe to connect the liquid outlet pipe and the liquid supply pipe, or to connect the liquid outlet pipe and the waste liquid pipe.

[0014] According to some embodiments of the present invention, a fixing clip is also included. The upper end of the fixing clip is provided with an elastic clip, which is clamped on the upper edge of the experimental tube. The fixing clip is provided with a limiting through hole, and the vent tube passes through the limiting through hole.

[0015] According to some embodiments of the present invention, the hanging assembly is provided with a first hook, and the lower end of the fixing clip is provided with a second hook. The first hook and the second hook are respectively fixedly connected to the ends of the threads at both ends of the specimen.

[0016] According to some embodiments of this utility model, the preheating beaker is provided in multiple ways.

[0017] According to some embodiments of this utility model, the constant temperature cavity has a built-in heating element, which includes a heating wire, a stainless steel sleeve and a silicone plug. The heating wire is built into the stainless steel sleeve, and the silicone plug and the two ends of the stainless steel sleeve are fixedly connected. The inside of the stainless steel sleeve is filled with magnesium oxide powder.

[0018] Additional aspects and advantages of this invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0019] The present invention will be further described below with reference to the accompanying drawings and embodiments, wherein:

[0020] Figure 1 This is a schematic diagram of the pipetting device according to an embodiment of the present invention;

[0021] Figure 2 This is a schematic diagram of the installation structure according to an embodiment of the present utility model;

[0022] Figure 3 This is a schematic diagram of the liquid storage beaker of the pipetting device according to an embodiment of the present invention;

[0023] Figure 4 This is a schematic diagram of the hanging assembly, ventilation assembly, and fixing clip of the pipetting device according to an embodiment of the present invention;

[0024] Figure 5 This is a schematic diagram of the water tank of the pipetting device according to an embodiment of the present invention;

[0025] Figure 6 This is a schematic diagram of the heating element of the pipetting device according to an embodiment of the present invention.

[0026] 100. Water tank; 110. Thermostatic chamber; 120. Heating element; 121. Heating wire; 122. Stainless steel sleeve; 123. Silicone plug; 124. Magnesium oxide powder;

[0027] 200, Experimental tube; 210, Liquid inlet; 220, First magnet; 230, First sealing groove;

[0028] 300, First mounting slot; 310, Liquid outlet; 311, Liquid supply pipe; 3111, First liquid pump; 312, Waste liquid pipe; 3121, Second liquid pump; 313, Liquid outlet pipe; 3131, Three-way reversing valve; 320, Second magnetic block; 330, Second sealing groove;

[0029] 400. Sealing ring;

[0030] 500. Second mounting slot;

[0031] 610. Liquid storage beaker; 620. Preheating beaker;

[0032] 700. Waste liquid tank; 710. Waste liquid chamber;

[0033] 800. Ventilation assembly; 810. Ventilation tubing;

[0034] 900. Hanging assembly; 910. Second hook;

[0035] 1000, Fixing clip; 1010, Elastic clip; 1011, Limiting through hole; 1020, First hook; Detailed Implementation

[0036] The embodiments of this utility model are described in detail below. Examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0037] In the description of this utility model, it should be understood that the directional descriptions, such as up, down, front, back, left, right, etc., indicate the directional or positional relationship based on the directional or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0038] In the description of this utility model, "several" means one or more, "multiple" means two or more, "greater than," "less than," and "exceeding" are understood to exclude the stated number, while "above," "below," and "within" are understood to include the stated number. If "first" or "second" is used in the description, it is only for the purpose of distinguishing technical features and should not be construed as indicating or implying relative importance, or implicitly indicating the number of indicated technical features, or implicitly indicating the order of the indicated technical features.

[0039] In the description of this utility model, unless otherwise explicitly defined, terms such as "setting," "installation," and "connection" should be interpreted broadly, and those skilled in the art can reasonably determine the specific meaning of the above terms in this utility model in conjunction with the specific content of the technical solution.

[0040] Reference Figure 1 The pipetting device of this utility model embodiment includes an installation structure, a liquid storage beaker 610, a preheating beaker 620, a waste liquid tank 700, a venting assembly 800, and a hanging assembly 900, wherein, referring to... Figure 2 The installation structure includes a water tank 100, an experimental tube 200, and a first mounting groove 300. The water tank 100 is equipped with a constant temperature chamber 110. An inlet hole 210 is provided at the bottom of the experimental tube 200, penetrating the bottom surface of the tube. A first magnet 220 is fixedly connected to the bottom surface of the experimental tube 200, and a first sealing groove 230 is provided on the bottom surface of the tube. The first mounting groove 300 is located at the bottom of the constant temperature chamber 110, and an outlet hole 310 is provided through the bottom of the first mounting groove 300. A second magnetic block 320 is fixed to the bottom surface, and a second sealing groove 330 is provided at the bottom of the mounting groove; wherein, the bottom end of the experimental tube 200 is embedded in the first mounting groove 300 so that the bottom surface of the experimental tube 200 abuts against the bottom surface of the first mounting groove 300, and the positions of the liquid outlet 310 and the liquid inlet 210 correspond, and the first magnet 220 and the second magnetic block 320 are magnetically connected, and the positions of the first sealing groove 230 and the second sealing groove 330 correspond, and a sealing ring 400 is embedded between the first sealing groove 230 and the second sealing groove 330.

[0041] In this embodiment of the invention, when installing the experimental tube 200 in the water tank 100, the bottom end of the experimental tube 200 is aligned with the first mounting groove 300 and embedded, with its bottom surface abutting against the bottom of the first mounting groove 300. At this time, the inlet hole 210 and the outlet hole 310 are aligned, and the first magnet 220 corresponds to the position of the second magnet 320, and is precisely attracted and fixed. Simultaneously, the sealing ring 400 is embedded between the two sealing grooves to form a seal. During installation, the inlet hole 210 and the outlet hole 310 are simultaneously connected, magnetically fixed, and sealed using the sealing ring 400, ensuring that the experimental liquid will not leak while facilitating quick assembly and disassembly of the experimental tube 200 by the experimental personnel.

[0042] Preferably, the first magnet 220 and the second magnetic block 320 can be made of high-temperature resistant magnetic materials, such as samarium cobalt magnets or coated neodymium iron boron magnets. This is to avoid the weakening of the fixing effect caused by the magnetic attenuation of ordinary magnets under high-temperature conditions.

[0043] Preferably, the sealing ring 400 is fixed in the second sealing groove 330. When the test tube 200 is installed, the first sealing groove 230 is pressed down and embedded into the second sealing groove 330 along with the test tube 200. The sealing ring 400 is compressed and undergoes elastic deformation, filling the microscopic gap between the contact surfaces of the two grooves, enhancing the sealing performance at the connection between the test tube 200 and the installation groove, preventing liquid leakage, and achieving an integrated operation of "positioning-sealing-fixing" in conjunction with the magnetic suction structure.

[0044] Furthermore, referring to Figures 1 to 6 A liquid storage beaker 610 is fixed in a constant temperature chamber 110. A liquid supply pipe 311 is provided between the liquid storage beaker 610 and the liquid outlet 310. A first liquid pump 3111 is provided in the liquid supply pipe 311. A preheating beaker 620 is placed in a constant temperature chamber 110. A waste liquid tank 700 and a water tank 100 are integrally formed. The waste liquid tank 700 is provided with a waste liquid chamber 710. A waste liquid pipe 312 is provided between the waste liquid chamber 710 and the liquid outlet 310. A second liquid pump 3121 is provided in the waste liquid pipe 312. A venting assembly 800 is connected to a venting pipe 810. One end of the venting pipe 810 extends into the experimental tube 200. A hanging assembly 900 is installed on the upper surface of the water tank 100. The hanging assembly 900 is used to hang specimens.

[0045] Based on the above technical features, after the user has installed the experimental tube 200, the specific usage steps are as follows:

[0046] Step 1: Control the first liquid pump 3111 to start, driving the liquid in the storage beaker 610 to enter the experimental tube 200 through the liquid supply pipe 311;

[0047] Step 2: The hanging assembly 900 is connected to the specimen by a thread, and the specimen is placed into the test tube 200;

[0048] Step 3: The ventilation component 800 vents air into the experimental tube 200 through the ventilation pipe 810 at a rate of 1 to 2 bubbles per second;

[0049] Step 4: After the experiment is completed, the waste liquid in the experimental tube 200 is discharged into the waste liquid chamber 710 through the waste liquid pipe 312 by the second liquid pump 3121.

[0050] Specifically, the hanging assembly 900 is used to mount the specimen, while the vent pipe 810 is used to maintain the air pressure environment in the experimental tube 200. The "liquid transfer-discharge" step is realized through the control of the first liquid pump 3111 and the second liquid pump 3121. Preferably, the "liquid transfer-discharge" only allows the liquid to flow between the storage beaker 610, the experimental tube 200 and the waste liquid tank 700. The storage beaker 610 is used to hold the experimental liquid to be used. When the amount of liquid in the storage beaker 610 decreases, the experimental liquid can be poured into the storage beaker 610 manually by hand. In addition, the constant temperature chamber 110 needs to be filled with warm water and the temperature of the warm water needs to be kept within a certain temperature range to ensure that the experimental temperature environment factors are met.

[0051] In some embodiments, refer to Figure 2 The second magnetic block 320 is annular, and the second sealing groove 330 is annular and located inside the second magnetic block 320. The liquid outlet 310 is located inside the second sealing groove 330. The second magnetic block 320, the second sealing groove 330, and the liquid outlet 310 are concentric. The annular second magnetic block 320 is arranged around the liquid outlet 310. When the annular first magnet 220 of the experimental tube 200 falls, the concentric structure automatically aligns the magnetic attraction center with the center of the liquid passage. The sealing groove synchronously surrounds the liquid outlet 310 to form an annular sealing band, improving connection stability and sealing reliability.

[0052] In some embodiments, refer to Figure 3 The constant temperature chamber 110 is also provided with a second mounting groove 500, in which the preheating beaker 620 is embedded. This facilitates the placement of the preheating beaker 620 and prevents it from shaking.

[0053] It is worth mentioning that, referring to Figure 2 The outlet hole 310 is connected to the outlet pipe 313. The outlet pipe 313, the supply pipe 311, and the waste pipe 312 are connected by a three-way reversing valve 3131, so that the outlet pipe 313 and the supply pipe 311 are connected, or the outlet pipe 313 and the waste pipe 312 are connected.

[0054] In actual experiments, the valve core of the three-way reversing valve 3131 rotates to switch the flow path: during liquid supply, the outlet pipe 313 is connected to the supply pipe 311, and the liquid flows from the storage beaker 610 to the experimental tube 200; during waste discharge, the outlet pipe 313 is connected to the waste liquid pipe 312, and the liquid in the experimental tube 200 is discharged into the waste liquid tank 700. Preferably, the three-way reversing valve 3131 is a solenoid valve, which realizes the automatic switching of liquid flow direction through electrical control valve, supports the automatic control of the entire process of "liquid supply-waste discharge-rinsing", and reduces manual operation errors.

[0055] Furthermore, each passage of the three-way directional valve 3131 is equipped with a check valve to prevent liquid backflow from causing contamination.

[0056] In some embodiments, refer to Figure 1 and Figure 4 The pipetting device of this embodiment further includes a fixing clamp 1000, with an elastic clamp 1010 at its upper end. The elastic clamp 1010 is clamped to the upper edge of the experimental tube 200. The fixing clamp 1000 has a limiting through hole 1011 through it, and the venting tube 810 passes through the limiting through hole 1011. The elastic clamp 1010 generates clamping force through deformation, tightly fastening the upper end of the fixing clamp 1000 to the top edge of the experimental tube 200. The venting tube 810 passes through the limiting through hole 1011, and its position is constrained by the fixing clamp 1000 to prevent shaking or displacement during ventilation, thus maintaining a stable ventilation effect.

[0057] Furthermore, the hanging assembly 900 is provided with a first hook 1020, and the lower end of the fixing clip 1000 is provided with a second hook 910. The first hook 1020 and the second hook 910 are respectively fixedly connected to the ends of the threads at both ends of the specimen. The threads at both ends of the specimen (such as an intestinal segment) are tied to the first hook 1020 and the second hook 910 respectively, stabilizing the specimen in the experimental tube 200.

[0058] In some embodiments, refer to Figure 5 Multiple preheating beakers 620 are provided. Multiple preheating beakers 620 are simultaneously embedded in the second mounting slot 500 of the constant temperature chamber 110, and different liquids (such as benchtop liquids and pharmaceutical liquids) are injected into them respectively. The constant temperature chamber 110 heats them to the preset temperature and sends them to the experimental tube 200 as needed.

[0059] In some embodiments, refer to Figure 5 and Figure 6 The constant temperature chamber 110 contains a heating element 120, which includes a heating wire 121, a stainless steel sleeve 122, and a silicone plug 123. The heating wire 121 is housed within the stainless steel sleeve 122. The silicone plug 123 is fixedly connected to both ends of the stainless steel sleeve 122. The stainless steel sleeve 122 is filled with magnesium oxide powder 124. When the heating wire 121 is energized, it generates Joule heat. The heat is conducted through the magnesium oxide powder 124 (an insulating and thermally conductive medium) to the stainless steel sleeve 122, and then transferred from the outer wall of the sleeve to the constant temperature chamber 110. The silicone plug 123 seals both ends of the sleeve to prevent liquid from seeping in.

[0060] The embodiments of the present utility model have been described in detail above with reference to the accompanying drawings. However, the present utility model is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present utility model.

Claims

1. An installation structure, characterized in that, include: The water tank (100) is equipped with a constant temperature chamber (110); The experimental tube (200) has a liquid inlet hole (210) at the bottom inside, the liquid inlet hole (210) penetrates the bottom surface of the experimental tube (200), a first magnet (220) is fixedly connected to the bottom surface of the experimental tube (200), and a first sealing groove (230) is provided on the bottom surface of the experimental tube (200). A first mounting groove (300) is provided at the bottom of the constant temperature chamber (110). A liquid outlet hole (310) is provided through the bottom of the first mounting groove (300). A second magnetic block (320) is fixed on the bottom surface of the mounting groove. A second sealing groove (330) is provided at the bottom of the mounting groove. The bottom end of the experimental tube (200) is embedded in the first mounting groove (300) so that the bottom surface of the experimental tube (200) and the bottom surface of the first mounting groove (300) abut against each other. The liquid outlet (310) and the liquid inlet (210) are in corresponding positions. The first magnet (220) and the second magnet (320) are magnetically connected. The first sealing groove (230) and the second sealing groove (330) are in corresponding positions. A sealing ring (400) is embedded between the first sealing groove (230) and the second sealing groove (330).

2. The installation structure according to claim 1, characterized in that, The sealing ring (400) is fixed in the second sealing groove (330).

3. The installation structure according to claim 1, characterized in that, The second magnetic block (320) is annular, the second sealing groove (330) is annular and located inside the second magnetic block (320), and the liquid outlet (310) is located inside the second sealing groove (330). The second magnetic block (320), the second sealing groove (330) and the liquid outlet (310) are concentric.

4. A pipetting apparatus, characterized in that, include: The mounting structure according to any one of claims 1 to 3; A liquid storage beaker (610) is fixed in the constant temperature chamber (110). A liquid supply pipe (311) is provided between the liquid storage beaker (610) and the liquid outlet (310). A first liquid pump (3111) is provided in the liquid supply pipe (311). A preheated beaker (620) is placed in the constant temperature chamber (110); Waste liquid tank (700) is integrally formed with water tank (100). Waste liquid tank (700) is provided with waste liquid cavity (710). Waste liquid pipe (312) is provided between waste liquid cavity (710) and liquid outlet (310). Waste liquid pipe (312) is provided with second liquid pump (3121). A ventilation assembly (800) is connected to a ventilation tube (810), one end of which extends into the experimental tube (200); A hanging assembly (900) is installed on the upper surface of the water tank (100), and the hanging assembly (900) is used to hang specimens.

5. The pipetting apparatus according to claim 4, characterized in that, The constant temperature chamber (110) is also provided with a second mounting groove (500), and the preheating beaker (620) is embedded in the second mounting groove (500).

6. The pipetting apparatus according to claim 4, characterized in that, The outlet hole (310) is connected to an outlet pipe (313). A three-way reversing valve (3131) is connected between the outlet pipe (313), the supply pipe (311), and the waste pipe (312) to connect the outlet pipe (313) and the supply pipe (311), or to connect the outlet pipe (313) and the waste pipe (312).

7. The pipetting apparatus according to claim 4, characterized in that, It also includes a fixing clip (1000), the upper end of which is provided with an elastic clip (1010), the elastic clip (1010) is clamped on the upper edge of the experimental tube (200), the fixing clip (1000) is provided with a limiting through hole (1011), and the vent tube (810) passes through the limiting through hole (1011).

8. The pipetting apparatus according to claim 7, characterized in that, The hanging assembly (900) is provided with a first hook (1020), and the lower end of the fixing clip (1000) is provided with a second hook (910). The first hook (1020) and the second hook (910) are respectively fixedly connected to the ends of the silk threads at both ends of the specimen.

9. The pipetting apparatus according to claim 4, characterized in that, Multiple preheating beakers (620) are provided.

10. The pipetting apparatus according to claim 4, characterized in that, The constant temperature chamber (110) has a built-in heating element (120), which includes a heating wire (121), a stainless steel sleeve (122) and a silicone plug (123). The heating wire (121) is built into the stainless steel sleeve (122), and the silicone plug (123) and the two ends of the stainless steel sleeve (122) are fixedly connected. The stainless steel sleeve (122) is filled with magnesium oxide powder (124).

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