Magnetic erector device

Abstract

The invention relates to a low-cost magnetic erector device that increases nitric oxide production via endothelial nitric oxide synthase from the endothelial layer, the innermost layer of the vascular structure, in the area where it is applied in vitro, without contact and without containing chemicals, increases the blood circulation of the tissue in the area where it is applied and also provides the possibility of repeated use and portable usability by means of its in vitro activity, contributes to vasodilatation in the area where it is applied with pulsed electromagnetic field (PEMF) and increases the synthesis of tissue growth factors such as vascular endothelial growth factor, does not cause painful stimuli and the power, frequency and duration of which can be adjusted.

Description

[0001] MAGNETIC ERECTOR DEVICE

[0002] Technical Field

[0003] The invention relates to a low-cost magnetic erector device that increases nitric oxide production via endothelial nitric oxide synthase from the endothelial layer, the innermost layer of the vascular structure, in the area where it is applied in vitro, without contact and without containing chemicals, increases the blood circulation of the tissue in the area where it is applied and also provides the possibility of repeated use and portable usability by means of its in vitro activity, contributes to vasodilatation in the area where it is applied with pulsed electromagnetic field (PEMF) and increases the synthesis of tissue growth factors such as vascular endothelial growth factor, does not cause painful stimuli and the power, frequency and duration of which can be adjusted.

[0004] Prior Art

[0005] Erectile dysfunction (ED) is the most common sexual problem and occurs in approximately 50% of men over the age of 50. ED is a condition that can cause lack of self-confidence and depression, which negatively affects people's quality of life. Normal erection is a state in which the hormonal and nervous systems are activated as a result of audio-visual or contact-based sexual stimulation, and blood flow increases with some chemical mediators secreted in the penis, filling the corpus cavernosum with blood, erection occurs and the veins close. After orgasmejaculation, the blood accumulated in the penis returns to the blood flow and the erection ends. For a healthy erection, the person's mental state must be appropriate. As erectile dysfunction continues, the dysfunction secondary to psychological problems continues progressively. This erectile dysfunction (impotence) may be due to organic causes such as diabetes, hypertension, obesity, hyperlipidaemia, previous surgery, smoking and alcohol, or it may be due to inorganic conditions such as psychological causes. The first treatment for erectile dysfunction is to change the person's lifestyle and get rid of excess weight, avoid smoking, alcohol and stress, and increase physical exercise as much as possible. In addition, drug therapy can be successful in up to 80% of patients by further dilating the penile blood vessels via nitric oxide with phosphodiesterase enzyme inhibitor drugs such as sildenafil, tadalafil, vardenafil and avanafil taken orally. Injection of vasodilators such as papaverine or alprostadil into the penis may also be effective. With ESWT (low intensity shock wave therapy), low-intensity shock waves are applied to the penis, resulting in the formation of new blood vessels in a total of 6-12 sessions, and they usually start to see the effects after 1 month. In PRP (Platelet Rich Plasma) treatment, which is applied in combination with ESWT treatment, the blood taken from the patient is taken into a special tube and passed through some processes to separate proteins (plasma) that stimulate cell renewal and is injected into the penis with a very thin needle, stimulating the regeneration of blood vessels and the formation of new vessels. Apart from this, penile prostheses can also provide artificial erection.

[0006] The document numbered US2006189839A1 in the state of the art describes the method and apparatus for strengthening penile erection using very low frequency ultra-weak electromagnetic field. A transducer produces an ultra-weak, pulsating magnetic field that is applied to the penis, causing an erection of the penis as a result of the magnetic field. Another aspect of the invention is an apparatus and method for treating medical conditions in women using a pulsating, extremely weak magnetic field. In accordance with various embodiments of the invention, the apparatus produces a pulsed or modulated “ultra-weak” electromagnetic field (i.e., an electromagnetic field of not more than about 5 microtesla in the volume occupied by the penis or, alternatively, of a peak intensity in a magnetic coil). The transducer directs an electromagnetic field (about 100 nanotesla or more) to the penis to enhance erection. Preferably, the frequency of the modulated or pulsed electromagnetic field is from about 15.94 Hertz to about 16 Hertz with a waveform that is sinusoidal. An apparatus configured according to the basic principle of the document operates by changing the magnetic coil current to obtain the desired frequency, amplitude and wave shape. The device of the invention does not have a combined feature. It lacks an applicator giving a combined energy.

[0007] In the prior art document numbered US2011263925A1 , a pulsed magnetic therapy device is described. It is a device to treat diseases and chronic conditions of the human body by inducing strong, short-term magnetic pulses close to a part of the body. The device comprises an electrical circuit pulsed at 1 to 25 pulses per second and an electromagnetic coil or inductor energized by a power source for use as therapeutic tools and an alternative medical treatment. The device comprises an electrical circuit that delivers pulsating current to an induction coil housed in a pentype handheld device to deliver a high-energy, pulsed magnetic field to target locations on the body. The pen is completely non-invasive and is used as a tool to direct magnetic energy to a specific part of the body. The device of the invention does not have a combined feature. It lacks an applicator giving a combined energy.

[0008] The prior art document numbered WO2013134492A1 describes neuromodulation and related systems and methods for the treatment of sexual disorders. Sympathetic nerve activity can be modulated along afferent and / or efferent pathways. Modulation may be accomplished using an intravascularly positioned catheter carrying a therapeutic device, such as a therapeutic device configured to use electrically induced, thermally induced, and / or chemically induced approaches to modulate nerves. The document is structured towards apparatus, systems and methods for treating sexual dysfunction and / or improving one or more measurable physiological parameters, such as ED, corresponding to sexual dysfunction, using penile and / or renal neuromodulation. The device of the invention does not have a combined feature. It lacks an applicator giving a combined energy.

[0009] In the document KR20200097407A in the state of the art, a treatment apparatus using pulsed magnetic field is described. The body part includes a pulsed magnetic field emitting unit having an electromagnet provided on the body to emit a pulsed magnetic field by receiving power from the body, and a control unit that can control the magnetic field emission of the pulsed magnetic field emission unit. The device of the invention does not have a combined feature. It lacks an applicator giving a combined energy.

[0010] The document numbered RU2730956C1 in the state of the art describes a method for treating patients with erectile dysfunction. Shock wave therapy procedures are performed using the Well-Wave apparatus, and the procedures are performed by applying the applicator to the patient's penis area. In order to treat patients with erectile dysfunction through a complex effect of shock waves, the patient is contacted on the penis in a supine position, in the projection of the corpus cavernosum and corpus spongiosum, using focused shock waves. A transcerebral effect is provided without a time interval by a pulsed magnetic field created by the wave apparatus at an energy flux density of -0.15 mJ / mm2, having a shock wave generation frequency is 3 Hz, and a pulse count of 1800 per procedure followed by an induction of 20 mT and an exposure of 20 minutes. The device of the invention does not have a combined feature. It lacks an applicator giving a combined energy.

[0011] Prior art document US2005131484A1 describes a method and system for providing pulsed electrical stimulation to provide treatment for erecti le / sexual dysfunction, prostatitis, prostatitis pain and chronic pelvic pain. The stimulation is directed to the cavernous nerve or its branches or portion thereof to provide therapy for erectile / sexual dysfunction. To provide treatment for chronic pelvic pain in prostatitis, the stimulation is directed to the pudendal nerve or its branches or portions thereof, the prostatic plexus or its branches or portions thereof, or the sacral splanchnic nerve or its branches or portions thereof. The device of the invention does not have a combined feature. It lacks an applicator giving a combined energy.

[0012] The fact that there is no contact-free device used for erectile dysfunction by using the pulsed magnetic field device together with radiofrequency and electromagnetic field in the inventions in the state of the art has necessitated an R&D study to be conducted in this field.

[0013] The Aim of the Invention

[0014] The main aim of the invention is to create a magnetic erector device that can be used in the treatment of erectile dysfunction, and uses radiofrequency (RF) together with electromagnetic field in a pulsed magnetic field (PMF) device and allows nitric oxide to cause vasodilatation in the vessels by increasing nitric oxide production via endothelial nitric oxide synthase from the endothelial layer, the innermost layer of the vascular structure, in the area where it is applied in vitro without contact, and thus increases blood flow to the tissue.

[0015] The aim of the invention is to create a magnetic erector device that can provide blood circulation to the tissue by increasing nitric oxide production in vitro without contact and minimises the potential for side effects as it does not contain a chemical structure.

[0016] Another aim of the invention is to create a magnetic erector device that provides repeated use and portable usability by means of in vitro activity.

[0017] Another aim of the invention is to create a magnetic erector device that reduces transmission losses since the 27.12 MHz oscillator, power unit and PCB applicator, crystal oscillator and power unit are designed as a single transistor circuit, the PCB is mounted in the corner of the applicator, thus no extra antenna cable is used.

[0018] The aim of the invention is to create a magnetic erector device in the PMF device with RF-EMA, which has a widening effect related to its ability to increase nitric oxide production on the vessels, eliminating many pathologies in clinical use.

[0019] Another aim of the invention is to create a low-cost magnetic erector device that contributes to vasodilation in the area where it is applied with RF-EMA in the PMF device, increases the synthesis of tissue growth factors such as vascular endothelial growth factor, does not cause painful stimuli, and whose power, frequency and duration can be adjusted.

[0020] An aim of the invention is to create a magnetic erector device comprising a 100 turns coil using 0.80 mm diameter enamel-plated copper coil conductor for a pulsed magnetic field.

[0021] Another aim of the invention is to create a magnetic erector device comprising both PMF and RF-EMA by adding an antenna design with a frequency of 27.12 MHz to a 15 cm x 15 cm printed circuit board (PCB) to create a radiofrequency magnetic field.

[0022] The aim of the invention is to enable monitoring of changes in the system using the screen by means of the presence of a 7-inch LCD screen on the device body.

[0023] Another aim of the invention is to prepare the antenna design with a frequency of 27.12 MHz on a printed circuit board (PCB) of 15 cm x 15 cm in order to combine the device's pulsed magnetic field and radiofrequency electromagnetic fields and to create a radiofrequency magnetic field. Another aim of the invention is to create a fireproof, non-stick, low heat permeability effect by making the filling material between the pulsed magnetic field and the radiofrequency electromagnetic field made of fibre or sponge or a similar material.

[0024] Another aim of the invention is to cover the application surface with a pillow fabric so that the antenna and coil applicator located inside do not disturb the patient during the treatment.

[0025] Another aim of the invention is to increase the synthesis of tissue growth factors such as vascular endothelial growth factor by contributing to vasodilation in the applied area by means of the pulsed electromagnetic field (PEMF).

[0026] Another aim of the invention is to create a more effective magnetic erector device that does not cause painful stimuli by combining the RF-EMA (27.12 MHz) method, which can heal scar tissue by expanding the vessels and increasing growth factor synthesis, with the pulsed magnetic field.

[0027] The aim of the invention is to create a device that is suitable for routine use without any negative effects on the tissue by increasing the effectiveness of the device by means of the pulsed magnetic field of 50 Hz, 0.5 mT, and helps to eliminate many pathologies in clinical use with its feature of increasing nitric oxide production on the vessels.

[0028] Description of Drawings

[0029] Figure - 1 Magnetic Erector Device and Applicator Pad Connection View

[0030] Figure - 2 Magnetic Erector Device Applicator Pad Detail View

[0031] Reference Numbers:

[0032] 1. Pulsed Magnetic Field Applicator

[0033] 2. Radiofrequency Applicator

[0034] 3. Radiofrequency Circuit

[0035] 4. Applicator Pad

[0036] 5. Radiofrequency Surface 6. Coil Surface

[0037] 7. Shielded Cable

[0038] 8. Power Unit

[0039] 9. Control Unit

[0040] 10. Plug

[0041] 11. Supply Cables

[0042] 12. Body

[0043] 13. Screen

[0044] Detailed Description of the Invention

[0045] The magnetic erector device which is the subject of the invention and the detail of which is shown in Figure 1 , comprises an applicator pad (4), a pulsed magnetic field (PMF) applicator (1 ) and a radiofrequency (RF) applicator (2 separated from each other -preferably- by fibre filling within said applicator pad (4). The magnetic erector device combines both pulsed magnetic field (PMF) and radiofrequency (RF-EMA) electromagnetic fields. The applicators (1 , 2) located in the applicator pad (4) are powered by supply cables (11 ). The magnetic erector device is preferably operated by providing it with electricity via a plug (10). The plug (10) comes out of the device body (12). Device settings can be made automatically by means of the LCD screen (13) on the device. Additionally, the magnetic erector device also comprises a power unit (8). To create a radiofrequency magnetic field, the antenna with a frequency of 27.12 MHz was prepared on a radiofrequency circuit (3) card with dimensions of 15 cm x 15 cm. For the pulsed magnetic field, a 200 turns coil was prepared using 0.3 mm diameter copper wire. The distance between the prepared copper coil and the antenna print on a 15 cm x 15 cm copper plaque will be 2.5 cm.

[0046] Magnetic erector device, which, with the effect of pulsed magnetic field or radiofrequency field, increases nitric oxide production and tissue blood supply in the applied area via endothelial nitric oxide synthase from the endothelial layer, the innermost layer of the vascular structure, comprises:

[0047] - at least one coil that creates a pulsed magnetic field effect, - at least one radiofrequency circuit (3) that creates a radiofrequency electromagnetic field effect,

[0048] - applicator pad (4), which increases the production of nitric oxide from the endothelial layer, the innermost layer of the vascular structure, through endothelial nitric oxide synthase and ensures its homogeneous distribution, with the electromagnetic effect occurring without contacting the application area, and

[0049] - control unit (9) that enables the power of the radiofrequency field and the pulsed magnetic field effect produced or the operating time or frequency of the device to be set and enables said pulsed magnetic field effect or radiofrequency electromagnetic field effect to be applied combined or separately.

[0050] It comprises said applicator pad (4) that comprises applicator (1 ) that produces a pulsed magnetic field on the coil surface (6), and a radiofrequency circuit (3) that produces a radiofrequency-electromagnetic field on the radiofrequency surface (5). In addition, said applicator pad (4) is made of fibre, sponge or a similar material and comprises a non-flammable, non-stick filling material that provides low heat permeability and thus enables both applicators (1 , 2) to generate the desired electromagnetic power without affecting each other. It comprises the supply cable (11 ) that enables the said applicator pad (4) to be connected to the device body (12). It comprises a coaxial (shielded) supply cable (11 ) that carries digital signals - preferably 50 Ohm - without being affected by the external environment. It comprises said coil, made of 0.3 mm diameter enamel coil conductor, structured in dimensions of 10 cm x 5 cm, to provide a pulsed magnetic field. In addition, said coil is a 100 turns coil with a field value of 0.5 mT at 6 V supply voltage. It comprises an LCD screen (13) located on said body (12) that enables tracking the changes. It comprises said radiofrequency circuit (3), which is connected to the corner of the radiofrequency applicator (2) and creates a radiofrequency field, eliminates the need for extra antenna cables and thus reduces transmission losses by means of the configuration of the power unit as a single-transistor PCB circuit antenna together with the crystal oscillator. It comprises the power switch that enables the device to be turned on and off, the LCD screen (13), the applicator pad (4) connected to the shielded (coaxial) cable (7), and the device body (12).

[0051] The body of the device (12) is made of plastic-coated material on aluminium. The power unit (8) is located inside the case. The connection of the power unit (8) is provided by coaxial or shielded cable. Changes on the system can be monitored via the touch screen. There is a power switch on the side surface (on / off button) of the body (12). The outer surface of the device measures 20 cm x 20 cm.

[0052] In order to separate the pulsed magnetic field applicator (1 ) and the radiofrequency applicator (2), a filling material is applied into the applicator pad (4) between the two. It is prepared by using - preferably - fibre or sponge which is fireproof, non-stick and has low heat permeability. In order to avoid discomfort to the patient during the treatment, the application surface between the antenna and the coil inside is covered with applicator pad (4) fabric.

[0053] Pulsed electromagnetic field (PEMF) contributes to vasodilation in the area where it is applied and also increases the synthesis of tissue growth factors such as vascular endothelial growth factor. The RF-EMA frequency used in this study is 27.12 MHz, and it can heal wound tissue by dilating vessels and increasing growth factor synthesis. In addition, in our preliminary studies with rats, it was observed that it increased the production of nitric oxide synthesis related to endothelial nitric oxide synthase in the rat brain within 30 minutes. The magnetic erector device is structured to combine two separate methods, pulsed electromagnetic field and radiofrequency methods, with an innovative combination to be more effective, do not cause painful stimuli, and have the above-mentioned features at a low cost. Pulsed electromagnetic field unit is produced so as to make sure that the magnetic field coils are of 200 turns and made of 0.8 mm diameter enamelled wire with dimensions of 10 cm x 5 cm. The coil creates a field value of 0.5 mT at 6 V supply voltage. There is a 27.12 MHz crystal oscillator, power unit (8) and PCB radiofrequency applicator (2). The crystal oscillator and power unit (8) are designed as a single transistor circuit and are connected to the corner of the radiofrequency circuit (3). Thus, transmission losses are reduced since no extra antenna cable is used.

[0054] The 27.12 MHz radiofrequency is reserved for medical use in the ISM band. ISM band is the band over which broadcasts can be made in many countries, without the need for a certificate or license for radio communication, complying with a certain output power limitation. Diathermy devices approved by the FDA (American Food and Drug Administration) also have this frequency and are frequently used in physiotherapy. This frequency, whose therapeutic effects have been proven in the literature, is also used in wound healing.

[0055] In a different preferred application of the magnetic erector device, it has been observed that the pulsed magnetic field of 50 Hz, 0.5 mT applied as an add-on to this method can increase the effectiveness of existing devices. Additionally, it is suitable for routine use because it has no negative effects on tissue. The widening effect of both methods, which increase nitric oxide production on the vessels, helps eliminate many pathologies in clinical use.

[0056] The magnetic erector device is capable of providing a homogeneous pulsed electromagnetic field and RF electromagnetic energy in the working environment, the power, frequency and duration of which can be adjusted. The target magnetic field is 0.5 mT (+ / - 10%) and the target electromagnetic field value is minimum 15 V / m. The frequency value that the device on the device body (12) will use for the pulsed electromagnetic field can be set in the range of 0 - 1 Hz and the power in the range of 0-1 mT, and the electromagnetic field value of 10 V / m - 15 V / m can be set for RF electromagnetic energy.

[0057] The device has a pad (4) made of fabric that can be easily cleaned and disinfected as an accessory. The pad (4) is an average small size, 30 x 20.5 cm thick. There is an applicator (1 ) that produces a pulsed magnetic field on one side of the pad (4), and a circuit (3) that produces RF-EMA and a PCB antenna on the other side. There is a filling material, preferably made of polyester fibre, which becomes 5 cm thick when compressed in the middle of both applicators (1 , 2). Thus, both applicators (1 , 2) provide the desired electromagnetic power without affecting each other. Both supply cables (11 ) connecting the pad (4) to the device are 50 Ohm coaxial (shielded) cables that are not affected by the external environment. With the device box that feeds the inductive applicator inside the pad (4), a 0.5 mT (+ / - 10%) field is produced at a distance of 30 cm to 50 cm perpendicular to the surface of the pad (4). The DC supply voltage of the magnetic field generator operates at 50% duty cycle. Thus, the magnetic field producing coils produce a pulsed magnetic field in the form of square waves under this intermittent supply.

[0058] The electromagnetic field generator is basically an integrated oscillator / amplifier circuit with quartz crystals. It is supplied with controllable DC voltage. The RF electromagnetic field generator circuit (3) produces RF energy at a frequency of 27.12 MHz (ISM Medical band, IEEE C95) and produces a 15 V / m electric field from a distance of 30 cm to 50 cm.

[0059] Each of the magnetic and electromagnetic field generators can be operated together or separately. The magnetic erector device is capable of working 24 / 7 without rest with the pulsed electromagnetic field or RF magnetic field, together or separately. Stop-start intervals can be adjusted in 15-minute intervals. It comprises a shielded (coaxial) cable that prevents the spread of electrical or magnetic fields.

[0060] The magnetic erector device can operate without shutting down (heavy duty) without being affected by the humidity and temperature changes in the environment. The device operates without disrupting EMC / EMI performance, without creating noise in the environment, without being affected by ambient noise and without changing the electrical parameters to which it is set. In addition to all these, the magnetic erector device will be able to deliver RF energy and pulsed magnetic energy at the fixed frequency and constant amplitude to which it has been set, separately or together, at the target point and target values, without being affected by each other.

Claims

CLAIMS1. A magnetic erector device, which by the effect of pulsed magnetic field or radiofrequency field, increases nitric oxide production and tissue blood supply at the applied area via endothelial nitric oxide synthase from the endothelial layer, the innermost layer of the vascular structure characterized by comprising:- at least one coil that creates a pulsed magnetic field effect,- at least one radiofrequency circuit (3) that creates a radiofrequency electromagnetic field effect,- an applicator pad (4), which increases the production of nitric oxide from the endothelial layer, the innermost layer of the vascular structure, through endothelial nitric oxide synthase and ensures its homogeneous distribution, with the electromagnetic effect occurring without contacting the application area, and- a control unit (9) that enables the power of the radiofrequency field and the pulsed magnetic field effect produced or the operating time or frequency of the device to be set and enables said pulsed magnetic field effect or radiofrequency electromagnetic field effect to be applied combined or separately.

2. The magnetic erector device according to claim 1 characterized by mentioned applicator pad (4) comprising: an applicator (1 ) that produces a pulsed magnetic field on a coil surface (6), and the radiofrequency circuit (3) that produces a radiofrequency-electromagnetic field on a radiofrequency surface (5).

3. The magnetic erector device according to claim 1 or claim 2 wherein mentioned applicator pad (4) made of fibre, sponge or a similar material and comprises: a non-flammable, non-stick filling material that provides low heat permeability and thus enables both applicators (1 , 2) to generate the desired electromagnetic power without affecting each other.

4. The magnetic erector device according to any of the previous claims, characterized by comprising; a supply cable (11 ) that enables said applicator pad (4) to be connected to a device body (12).

5. The magnetic erector device according to any of the previous claims characterized by comprising; a coaxial (shielded) supply cable (11) that carries digital signals without being affected by the external environment - preferably 50 Ohm.

6. The magnetic erector device according to any of the previous claims, characterized by comprising; the coil made of enamelled coil conductor with a diameter of 0.3 mm and structured in 10 cm x 5 cm dimensions to provide a pulsed magnetic field.

7. The magnetic erector device according to any of the previous claims characterized by comprising; the 100 turns coil with 0.5 mT field value at 6 V supply voltage.

8. The magnetic erector device according to any of the previous claims, characterized by comprising; an LCD screen (13) located on mentioned body (12), allowing changes to be tracked from said control unit (9).

9. The magnetic erector device according to any of the previous claims wherein: mentioned radiofrequency circuit (3) that is connected to the corner of the radiofrequency applicator (2) and creates a radiofrequency field, eliminates the need for extra antenna cables and thus reduces transmission losses by means of the configuration of the power unit as a single-transistor PCB circuit antenna together with the crystal oscillator.10.The magnetic erector device according to any of the previous claims, characterized by comprising; a power switch that enables the device to be turned on and off, the LCD screen (13), the applicator pad (4) connected to the shielded (coaxial) cable (7) and the device body (12).

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