The invention discloses glue for plywood with high weather resistance. The glue is prepared from, by mass, 20%-30% of weather-resistant materials, 10%-20% of mixed powder, 15%-25% of lignin mixed liquor, 0.5%-1% of protease, 2%-5% of an initiator, 1%-3% of cellulose and 30%-50% of water. The processing technology of the glue comprises the following steps: (1) adding water and the mixed powder intoa reaction kettle according to a ratio, stirring, adding the lignin mixed solution and cellulose according to a ratio, and stirring while keeping the temperature to obtain a mixed solution A, and (2)after cooling, adding a weather-proof material and protease into the mixed solution A according to a ratio, uniformly stirring, adding the initiator according to a ratio, and stirring to obtain a glue finished product. The preparation process is simple, the adopted raw materials are easy to obtain, the production cost is controllable, all the raw material components are reasonably matched, and the glue prepared through the method has the advantages of being free of formaldehyde content, high in bonding strength, good in water resistance, easy to apply and not prone to mildewing.