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2 results about "Marie disease" patented technology
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Charcot–Marie–Tooth disease (CMT) is one of the hereditary motor and sensory neuropathies, a group of varied inherited disorders of the peripheral nervous system characterized by progressive loss of muscle tissue and touch sensation across various parts of the body.
Methods of treating charcot-marie-tooth disease
A method of treating Charcot Marie Tooth Disease in a human in need thereof. The method comprises systemically administering to the human a non-antibacterial tetracycline compound or antibacterial tetracycline compound, in an amount that is effective to treat Charcot Marie Tooth Disease but has substantially no antibacterial activity.
Owner:CMTX BIOTECH INC
A1h-benzo[c][1,2]thiadiazine-2,2-dioxides bearing heterocyclic linkers as selective histone deacetylase 6 inhibitors
PendingUS20250171433A1Organic active ingredientsNervous disorderAutoimmune conditionHistone deacetylase
Histone deacetylases inhibitors (HDACbls) and compositions containing the same are disclosed. Methods of treating diseases and conditions wherein inhibition of HDAC6 provides a benefit, like a cancer, a neurodegenerative disorder, a neurological disease including peripheral neuropathies such as Charcot Marie Tooth disease, traumatic brain injury, stroke, malaria, an autoimmune disease, autism, and inflammation, also are disclosed.
![A1h-benzo[c][1,2]thiadiazine-2,2-dioxides bearing heterocyclic linkers as selective histone deacetylase 6 inhibitors](https://images-eureka.patsnap.com/patent_img/55a53817-5672-431c-8455-920344def3df/US20250171433A1-D00000.png "A1h-benzo[c][1,2]thiadiazine-2,2-dioxides bearing heterocyclic linkers as selective histone deacetylase 6 inhibitors")
Owner:GEORGETOWN UNIV