43results about How to "Novel structure type" patented technology

The invention belongs to the field of medical technology, and relates to a benzoyl substituted thiazolo[3,2-b]-1,2,4-triazine derivative and an application thereof. The benzoyl substituted thiazolo[3,2-b]-1,2,4-triazine derivative comprises a stereoisomer and pharmaceutically acceptable salt of the benzoyl substituted thiazolo[3,2-b]-1,2,4-triazine derivative, wherein the structural general formula is shown in the specification; and the benzoyl substituted thiazolo[3,2-b]-1,2,4-triazine derivative and the pharmaceutically acceptable acid-added salt of the compound can be combined with the existing medicine or independently used as an acetylcholin esterase inhibitor and used for improving the memory of the patients suffering from dementia and Alzheimer disease. Compared with the existing Chinese patent, the 6-site side chain of thiazolo[3,2-b]-1,2,4-triazine is obviously changed, and the inhibition ratio of a sample against acetylcholin esterase is obviously improved.