1results about How to "Reduce TG content" patented technology

This invention provides oleanolic acid-modified HG-type pectin nanomicelles, their preparation method, and applications. The preparation method of the HG-type pectin nanomicelles includes: esterifying 3,3'-dithiodipropionic acid and oleanolic acid to obtain SS-OA; esterifying SS-OA and HG-type pectin to obtain oleanolic acid-modified HG-type pectin; dissolving the oleanolic acid-modified HG-type pectin and dispersing it ultrasonically to obtain oleanolic acid-modified HG-type pectin nanomicelles. The oleanolic acid-modified HG-type pectin nanomicelles of this invention combine the functional activities of HG-type pectin and oleanolic acid, as well as the redox responsiveness of 3,3'-dithiodipropionic acid, constructing nanomicelles that respond to ROS generated during alcohol metabolism. They exhibit amphiphilicity and good biocompatibility, and can be used to prepare drugs to alleviate chronic alcoholic liver injury.