Qianlieantong capsules and preparation method thereof

Abstract

The invention discloses Qianlieantong capsules and a preparation method thereof. The Qianlieantong capsules are prepared from the following raw materials in parts by weight: 190-210 parts of amur corktree bark, 190-210 parts of red paeony root, 90-110 parts of Danshen root, 130-150 parts of peach seeds, 110-130 parts of hirsute shiny bugleweed herb, 110-130 parts of combined spicebush root, 70-90 parts of cowherb seed, 70-90 parts of dahurian angelica root, 1-5 parts of talcum powder and 5-15 parts of starch. The Qianlieantong capsules have the effects of clearing heat and promoting diuresis, purifying blood, removing pathogenic bacteria, viruses and toxins, activating blood and removing blood stasis and strengthening healthy qi to eliminate pathogens and are used for treating prostatitis, benign prostatic hyperplasia, urologic diseases such as gonococcal and non-gonococcal acute and chronic urethritis caused by verruca acuminate, herpes simplex virus, and the like, and the symptoms, such as frequent urination, urgent urination, dysuria, acraturesis, urination difficulty, bifurcation of urination, continuous urination, dribble of urine, red and swollen urethral orifice or burning discomfort of the urethral orifice, secreta outflow from the urethral orifice, gonorrhea, radiating pain in perinea and hypogastria, limb weakness, aching and limp waist, sensation of chill and lassitude.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a Qianlie Antong capsule and a preparation method thereof. Background technique [0002] In recent years, with the changes in people's lifestyles and work patterns, prostatitis has become a disease with a high incidence rate that plagues people, bringing endless pain to people's daily life. Prostatitis is currently divided into two types: acute and chronic. Western medicine treatment of prostate diseases is aimed at the etiology of pathogenic bacteria. In recent years, Western medicine has repeatedly used broad-spectrum antibiotics in large quantities in the treatment of prostate diseases. The side effects are large, the effect is not obvious, recurrence is easy, and it causes obvious liver and kidney damage. At the same time, it will lead to the imbalance of flora in the patient's body, the decline of immunity, and the reproduction of pathogens...

AI Technical Summary

Problems solved by technology

However, the disintegration speed of Qianlie Antong Tablets is slow and the bioavailability is not high

The extraction process of Qianlie Antong Tablets is backward, and the traditional water decoction method is used for extraction. This extraction method has defects in various aspects such as "coarse" and "large": Orchid contains volatile oil components, while Danshen contains fat-soluble diterpenes, and peach kernels contain unsaturated fatty acids.

These fat-soluble components have low affinity to water, and the extraction rate of fat-soluble components is low by decocting in water. At the same time, the volatile oil components are easy to decompose at high temperature, which affects the quality of volatile oil; "big" is Qianlie Antong's The decoction liquid not only contains alkaloids, terpenes, sterols and other highly effective ingredients, but also contains a large amount of hydrophilic macromolecules such as starch, protein, mucus, polysaccharides, etc. Most of these macromolecules are not It has medicinal ingredients, but occupies a large volume, which increases the dosage. At the same time, starch, polysaccharides and other substances also have hygroscopicity, which makes it easy to absorb moisture during storage and affects the stability of Qianlie Antong Tablets

[0004] Subsequently, Qianlie Antong Capsules were developed. The disintegration speed of Qianlie Antong Capsules is faster than that of Qianlie Antong Tablets, but the bioavailability is still not high due to backward extraction and separation processes.

At the same time, the moisture-proof performance of Qianlie Antong Capsules is not as good as that of Qianlie Antong Tablets. Under improper storage conditions, the appearance of the contents of the capsules will become darker, agglomerated, or even mildewed, thereby affecting the quality and curative effect of Qianlie Antong Capsules. Difficulties in production and storage, reducing drug stability