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New application of a traditional Chinese medicine preparation as a drug for treating osteoarthritis

A traditional Chinese medicine preparation and technology for osteoarthritis, applied in the field of new drug use, can solve the problems of patients' inconvenience and susceptibility to infection

Active Publication Date: 2021-05-14
GUANGXI YINGKANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage is that a complete aseptic operation must be performed by a specialized orthopedic surgeon, otherwise infection will easily occur; at this stage, many township hospitals do not have the conditions to operate this therapy, and patients need to travel long distances to hospitals in big cities for treatment. a lot of inconvenience

Method used

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  • New application of a traditional Chinese medicine preparation as a drug for treating osteoarthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The traditional Chinese medicine preparation prepared by adopting the following manufacturing process steps can treat rheumatoid arthritis, rheumatoid arthritis, frozen shoulder and osteoarthritis at the same time:

[0031] (1) Take 700 parts by weight of red fish eye, 700 parts of nine layers of wind, 450 parts of Ivy clover, 450 parts of mountain wind, 160 parts of liangmianzhen, 25 parts of Panax notoginseng stems and leaves, and grind them into coarse powder respectively, pass 8 ~10 mesh sieve, spare;

[0032] (2) Put the coarse powder in an extraction tank, add ethanol with a volume concentration of 50-70%, and reflux extraction for 3 times, each time for 2 hours, and filter the extract with a 180-200 mesh sieve to obtain the filtrate; the coarse powder is calculated by weight, Volume concentration is 50-70% ethanol by volume, coarse powder: volume concentration is 50-70% ethanol=1:(4-6);

[0033] (3) Use a vacuum device to recover ethanol from the filtrate and co...

Embodiment 2

[0037] The traditional Chinese medicine preparation prepared by adopting the following manufacturing process steps can treat rheumatoid arthritis, rheumatoid arthritis, frozen shoulder and osteoarthritis at the same time:

[0038] (1) Take 846.7 parts of red fish eye, 846.7 parts of nine layers of wind, 564.5 parts of clover, 564.5 parts of mountain wind, 170.9 parts of two-faced needle, 28.2 parts of Panax notoginseng stems and leaves, and grind them into coarse powder respectively. ~10 mesh sieve, spare;

[0039] (2) Put the coarse powder in an extraction tank, add ethanol with a volume concentration of 50-70%, and reflux extraction for 3 times, each time for 2 hours, and filter the extract with a 180-200 mesh sieve to obtain the filtrate; the coarse powder is calculated by weight, Volume concentration is 50-70% ethanol by volume, coarse powder: volume concentration is 50-70% ethanol=1:(4-6);

[0040] (3) Use a vacuum device to recover ethanol from the filtrate and concentr...

Embodiment 3

[0044] The traditional Chinese medicine preparation prepared by adopting the following manufacturing process steps can treat rheumatoid arthritis, rheumatoid arthritis, frozen shoulder and osteoarthritis at the same time:

[0045] (1) Take 846.7 parts of red fish eye, 846.7 parts of nine layers of wind, 564.5 parts of clover, 564.5 parts of Dafeng moi, 170.9 parts of two-faced needle, 28.2 parts of Panax notoginseng stems and leaves, and grind them into coarse powder respectively, pass 8 ~ 10 mesh sieve, spare;

[0046] (2) Put the coarse powder in an extraction tank, add ethanol with a volume concentration of 60%, and reflux extraction for 3 times, each time for 2 hours, and filter the extract with a 180-200 mesh sieve to obtain the filtrate; the coarse powder is calculated by weight, volume concentration 50-70% ethanol by volume, coarse powder: volume concentration is 50-70% ethanol=1:(4-6);

[0047] (3) Use a vacuum device to recover ethanol from the filtrate and concentra...

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Abstract

A traditional Chinese medicine preparation is used as a new medicine for treating osteoarthritis. The clinical symptoms of osteoarthritis are: degeneration and destruction of articular cartilage, subchondral bone sclerosis or cystic degeneration, bone hyperplasia at the joint edge, synovial hyperplasia, Joint capsule contracture, ligament laxity or contracture, muscle atrophy and weakness, etc.; the traditional Chinese medicine preparation is made of the following raw materials in parts by weight: 700-1100 parts of red fish eye, 700-1100 parts of nine-layer wind, 450-800 parts of Ivy clover , 450-800 parts of Shanfeng, 160-320 parts of Liangmianzhen, 25-40 parts of Panax notoginseng stems and leaves, among which Shanfeng can also be replaced by an equal amount of Dafeng AI. The present invention uses the medicine originally used for treating rheumatoid arthritis, frozen shoulder and rheumatoid arthritis to treat osteoarthritis, and has remarkable curative effect in treating osteoarthritis, expands the indications of the original medicine, and provides a clinical A new drug for the prevention and treatment of osteoarthritis.

Description

technical field [0001] The invention belongs to the technical field of new uses of medicines, in particular to a new use of traditional Chinese medicine preparations as medicines for treating osteoarthritis. [0002] technical background [0003] Huatuo Fengtongbao Tablets (formerly known as "Fengshiling Tablets") is a traditional Chinese medicine preparation produced by Guangxi Baiyunshan Yingkang Pharmaceutical Co., Ltd. (formerly known as Guangxi Yingkang Pharmaceutical Co., Ltd. Pharmacy School Pharmaceutical Factory), the current standard of the drug is the national drug standard YBZ01972008, the product has won the third prize of Guangxi Science and Technology Progress Award, the second prize of Guangxi Medical and Health Science and Technology Progress Award, and has been listed as a national second-class protected variety of traditional Chinese medicine. [0004] Since its launch, Huatuo Fengtongbao Tablets have been favored by patients, and have a good therapeutic ef...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/758A61P19/02A61P29/00A61P21/00A61P19/04
CPCA61K36/185A61K36/21A61K36/258A61K36/28A61K36/47A61K36/758A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 黄若干蓝晓东彭富全程宏辉黄平权蒙珍庞洪梁峰梁杰敏
Owner GUANGXI YINGKANG PHARMA
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