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A kind of traditional Chinese medicine compound preparation for treating rheumatoid arthritis and preparation method thereof

A compound preparation and arthritic technology, applied in the field of traditional Chinese medicine preparations, can solve the problems of difficult adherence for patients, large side effects, poor curative effect, etc., and achieve the effects of convenient use, small side effects and low price

Active Publication Date: 2021-04-16
ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, there was a lack of effective diagnosis and treatment methods for this type of disease, and because most of them are chronic diseases, people generally do not know enough about this type of disease, and because the etiology is unknown, there are many treatments and the curative effect is not good. Western medicine anti-inflammatory analgesics and hormone therapy are commonly used In the beginning, the pain may be temporarily relieved, but as time goes by, joint deformities gradually appear, resulting in disability, and even visceral damage, which can be life-threatening in severe cases
[0003] Due to the large side effects of western medicine, there is a great demand for Chinese medicines for the effective treatment of rheumatoid arthritis. The traditional Chinese medicine used in my country for the treatment of rheumatoid arthritis is mainly Tripterygium wilfordii, but it is harmful to the heart and liver. , kidney, hematopoietic system, gastrointestinal tract, reproductive system and other serious side effects make it difficult for many patients to adhere to

Method used

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  • A kind of traditional Chinese medicine compound preparation for treating rheumatoid arthritis and preparation method thereof
  • A kind of traditional Chinese medicine compound preparation for treating rheumatoid arthritis and preparation method thereof
  • A kind of traditional Chinese medicine compound preparation for treating rheumatoid arthritis and preparation method thereof

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Experimental program
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Effect test

Embodiment 1

[0031] 1) Wash 9g of Qingfengteng, 10g of Angelica, 8g of Radix Paeoniae Alba, 9g of Duhuo, 7g of Gentiana chinensis, 5g of Guizhi, 10g of Astragalus membranaceus and 9g of licorice, mix and add 8 times the weight of 70% ethanol to reflux twice, each time For 1 hour, combine the two extracts, filter and concentrate to obtain a liquid extract with a specific gravity of 1.0 at 60°C;

[0032] 2), adopt conventional preparation technology, make tablet.

Embodiment 2

[0034] 1) Wash 15g of Qingfengteng, 8g of Angelica, 10g of Radix Paeoniae Alba, 7g of Duhuo, 9g of Gentiana chinensis, 3g of Guizhi, 13g of Astragalus membranaceus and 7g of licorice, mix and add 7.5 times the weight of 70% ethanol to reflux twice, each time For 1 hour, combine the two extracts, filter and concentrate to obtain a liquid extract with a specific gravity of 1.05 at 60°C;

[0035] 2), adopt conventional preparation technology, make gel ointment.

Embodiment 3

[0037] 1), wash 12g of Qingfengteng, 12g of angelica, 6g of white peony root, 3g of Duhuo, 10g of Gentiana chinensis, 10g of cassia twig, 9g of astragalus and 2g of licorice, mix and add 6.5 times the weight of 70% ethanol to reflux twice, each time For 1 hour, combine the two extracts, filter and concentrate to obtain a liquid extract with a specific gravity of 1.1 at 60°C;

[0038] 2), adopt conventional preparation technology, make capsule

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Abstract

A traditional Chinese medicine compound preparation for treating rheumatoid arthritis and a preparation method thereof belong to the technical field of traditional Chinese medicine preparations. The active ingredients of the traditional Chinese medicine compound preparation for treating rheumatoid arthritis are composed of 6-15 parts of Qingfengteng, 6-12 parts of Angelica, 6-12 parts of Radix Paeoniae Alba, 3-10 parts of Duhuo, 3-10 parts of Gentiana chinensis, 3-10 parts of Guizhi, 9-15 parts of astragalus and 2-10 parts of licorice. The traditional Chinese medicine compound preparation for treating rheumatoid arthritis of the present invention selects sinomenine, angelica, white peony root, Duhuo, Gentiana chinensis, cassia twig, astragalus, and licorice for compatibility, and combines these medicines so that the efficacy of each medicine produces a synergistic effect, thereby being able to Effective treatment of early, middle and late rheumatoid arthritis, good curative effect and small side effects. It also has a certain therapeutic effect on osteoarthritis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a compound traditional Chinese medicine preparation for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (RA) is a systemic autoimmune disease mainly characterized by joint lesions, and it is also a common disease, non-suppurative, multiple joint disease, with a relatively high clinical incidence and great harm . And it can occur in people of all age groups, and the incidence rate increases with age. At present, the incidence of rheumatic diseases in mainland China is increasing year by year. Among them, the most serious rheumatoid arthritis has more than 4.4 million patients. The pathology of RA arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of inflammatory cells in the interstitium, and Neogenesis of microves...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61K36/65A61P19/02A61P37/02
CPCA61K36/232A61K36/481A61K36/484A61K36/51A61K36/54A61K36/59A61K36/65A61K36/71A61K2300/00
Inventor 储晓琴桂双英李争光黄洁
Owner ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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