A biological enzyme temperature control reaction equipment

Abstract

The present invention belongs to the field of biological enzyme production equipment, and specifically is a biological enzyme temperature control reaction equipment, comprising a base, a machine base fixed on the top of the base, a rotating cross frame arranged on the top of the machine base, and a temperature control reaction equipment body arranged at the front and rear of the top of the rotating cross frame. The present invention drives a rotating column by a motor to make the rotating cross frame reciprocate with the rotating column as the center of a circle, and the rotating rotating cross frame drives the temperature control reaction equipment body at the two ends of the top to reciprocate. When the temperature control reaction equipment body reciprocates, the raw material tends to maintain the original motion state due to inertia. At the same time, the centrifugal force causes the raw material to move to the edge of the temperature control reaction equipment body. In the process of reciprocating rotation, the inertia and centrifugal force are constantly changing, resulting in the raw material flowing back and forth and exchanging between different positions, thereby achieving mixing. Compared with stirring, the reciprocating rotation for mixing the raw materials can reduce the shear force and reduce the risk of direct damage to the enzyme structure.

Description

Technical Field

[0001] The invention belongs to the field of biological enzyme production equipment, in particular to a biological enzyme temperature control reaction equipment. Background Art

[0002] Bio-enzyme temperature control reaction equipment is a bio-enzyme production equipment used to control the temperature of bio-enzyme catalytic reactions. Bio-enzyme temperature control reaction equipment can provide the most suitable temperature environment for bio-enzymes, thereby promoting efficient, stable and controllable reactions.

[0003] The prior art also proposes some solutions for bio-enzyme production equipment. For example, a Chinese patent with authorization announcement number CN213624179U discloses a bio-enzyme temperature control reaction device including: a reaction tank, a temperature control sleeve and a heat conducting rod. The temperature control sleeve is arranged at the lower part of the outer circle of the reaction tank. The application improves production efficiency by rapidly heating or cooling the bio-enzyme solution in the reaction tank.

[0004] Although the above technical solution can quickly heat or cool down, increase the temperature of the biological enzyme reaction, and make the reaction temperature in the equipment quickly reach the optimal temperature, in the actual reaction, in order to ensure the uniform contact of the reaction raw materials, the raw materials need to be stirred so that the raw materials are fully mixed and contacted. However, the enzyme is a protein, and its structure is crucial to maintaining its catalytic activity. Although stirring can make the raw materials fully mixed and contacted, the shear force generated during the stirring process may cause the structure of the enzyme to change, thereby affecting its activity.

[0005] To this end, the present invention provides a biological enzyme temperature control reaction equipment. Summary of the invention

[0006] In order to make up for the deficiencies of the prior art, at least one technical problem raised in the background technology is solved.

[0007] The technical solution adopted by the present invention to solve its technical problems is: a biological enzyme temperature control reaction equipment described in the present invention includes a base, a machine base fixed on the top of the base, a rotating cross frame arranged at the top of the machine base, and a temperature control reaction equipment body arranged at the front and rear of the top of the rotating cross frame, a rotating component is arranged at the bottom of the rotating cross frame, shaking components are arranged on both sides of the temperature control reaction equipment body, push-pull components are arranged at the front and rear ends of the rotating cross frame, and a connecting component is arranged at the top of the temperature control reaction equipment body.

[0008] Preferably, the rotating assembly includes a support base arranged at the bottom of the rotating cross frame, the support base is fixed to the top of the machine base, a guide groove is opened on the outer side of the top of the support base, guide blocks are fixed at the front and rear ends of the bottom of the rotating cross frame, the guide blocks are placed in the guide grooves, a rotating column is fixed at the middle position of the bottom of the rotating cross frame, the rotating column passes through the middle position of the support base, a motor is installed at the bottom end of the machine base, and the rotating shaft at the top of the motor is fixedly connected to the bottom of the rotating column.

[0009] Preferably, the size of the guide groove matches the size of the guide block, and the guide block can rotate in the guide groove.

[0010] Preferably, the shaking assembly includes supporting side frames arranged on both sides of the temperature-controlled reaction equipment body, the bottom of the supporting side frames is fixedly connected to the top of the rotating cross frame, a connecting groove is opened inside the supporting side frames, a connecting block is arranged inside the connecting groove, the connecting block is fixed to both sides of the temperature-controlled reaction equipment body, a hinge block is fixed at the bottom of the temperature-controlled reaction equipment body, a hinge seat 1 is arranged at the bottom of the hinge block, the bottom of the hinge seat 1 is fixedly connected to the top of the rotating cross frame, and the hinge seat 1 is hinged to the hinge block.

[0011] Preferably, the size of the connecting groove matches the size of the connecting block, and the connecting block can slide inside the connecting groove.

[0012] Preferably, the push-pull assembly includes brackets arranged at the front and rear ends of the rotating horizontal frame, the two sides of the brackets are fixedly connected to the supporting side frames, a rotating rod is rotatably arranged inside the bracket, a gear 1 is arranged at the bottom of the bracket, the top of the gear 1 is fixedly connected to the bottom of the rotating rod, a gear ring is fixed to the outside of the machine base, the gear ring is meshed with the gear 1, a push-pull frame is arranged on the top of the bracket, a gear 2 is arranged inside the push-pull frame, and the bottom of the gear 2 is fixedly connected to the top of the rotating rod.

[0013] Preferably, gear 2 is of half-tooth design, and internal teeth are provided on both sides of the push-pull frame.

[0014] Preferably, the push-pull assembly also includes side blocks arranged on both sides of the push-pull frame, the side blocks are fixed to both sides of the top of the bracket, limiting grooves are opened inside the side blocks, limiting blocks are arranged inside the limiting grooves, and the limiting blocks are fixed to both sides of the push-pull frame.

[0015] Preferably, the size of the limiting groove matches the size of the limiting block, and the limiting block can slide inside the limiting groove.

[0016] Preferably, the connecting assembly includes an articulated seat three fixed at the middle position of the top of the main body of the temperature-controlled reaction equipment, the top of the articulated seat three is hinged with a push-pull rod, the top of the push-pull rod is hinged with an articulated seat two, the end of the articulated seat two is fixed with a connecting column, and one end of the connecting column is fixedly connected to the end of the push-pull frame.

[0017] The beneficial effects of the present invention are as follows:

[0018] 1. The biological enzyme temperature control reaction equipment described in the present invention drives the rotating column by a motor to make the rotating cross frame reciprocate with the rotating column as the center, and the rotating rotating cross frame drives the temperature control reaction equipment body at the top two ends to reciprocate. When the temperature control reaction equipment body reciprocates, the raw materials tend to maintain their original state of motion due to inertia. At the same time, the centrifugal force will cause the raw materials to move to the edge of the temperature control reaction equipment body. During the reciprocating rotation, the inertia and centrifugal force are constantly changing, causing the raw materials to flow back and forth and exchange between different positions, thereby achieving mixing. Compared with stirring, reciprocating rotation to mix the raw materials can reduce shear force and reduce the risk of direct damage to the enzyme structure.

[0019] 2. The biological enzyme temperature control reaction equipment described in the present invention, when the temperature control reaction equipment body rotates, cooperates with the push-pull component and the connecting component to reciprocately push and pull the top of the temperature control reaction equipment body. Since the bottom of the temperature control reaction equipment body is hinged to the top of the rotating cross frame through a hinge seat and a hinge block, when the push-pull component and the connecting component reciprocate to push and pull the temperature control reaction equipment body, the temperature control reaction equipment body keeps shaking. The reciprocating rotation of the temperature control reaction equipment body causes the raw materials to move in a plane, and the reciprocating shaking introduces movement perpendicular to the rotation plane, causing the raw materials to shift and exchange in more directions, thereby more comprehensively disrupting the distribution of the raw materials and improving the uniformity of mixing. In addition, movement in more directions increases the chances of collision and contact between raw material molecules, which helps molecular diffusion and accelerates the mixing of different components. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] The present invention will be further described below in conjunction with the accompanying drawings.

[0021] Figure 1 It is the overall structural diagram of the present invention;

[0022] Figure 2 It is a disassembled diagram of the overall structure in the present invention;

[0023] Figure 3 It is a partial structural cross-sectional view of the present invention;

[0024] Figure 4 It is a partial structural diagram of the present invention;

[0025] Figure 5 It is a partial structural diagram of the push-pull assembly in the present invention;

[0026] Figure 6 It is a local structure split diagram in the present invention;

[0027] Figure 7 This is a structural breakdown diagram of the push-pull assembly in the present invention;

[0028] In the figure: 1. base; 2. machine base; 3. rotating assembly; 31. support seat; 32. guide groove; 33. guide block; 34. motor; 35. rotating column; 4. rotating cross frame; 5. temperature control reaction equipment body; 6. shaking assembly; 61. supporting side frame; 62. connecting groove; 63. connecting block; 64. hinge seat one; 65. hinge block; 7. push-pull assembly; 71. bracket; 72. rotating rod; 73. gear one; 74. push-pull frame; 75. gear ring; 76. gear two; 77. side block; 78. limit groove; 79. limit block; 8. connecting assembly; 81. connecting column; 82. hinge seat two; 83. push-pull rod; 84. hinge seat three. DETAILED DESCRIPTION

[0029] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific implementation methods.

[0030] like Figures 1 to 7 As shown, a biological enzyme temperature control reaction equipment of an embodiment of the present invention includes a base 1, a machine base 2 fixed on the top of the base 1, a rotating cross frame 4 arranged at the top of the machine base 2, and a temperature control reaction equipment body 5 arranged at the front and rear of the top of the rotating cross frame 4, a rotating component 3 is arranged at the bottom of the rotating cross frame 4, shaking components 6 are arranged on both sides of the temperature control reaction equipment body 5, push-pull components 7 are arranged at the front and rear ends of the rotating cross frame 4, and a connecting component 8 is arranged at the top of the temperature control reaction equipment body 5.

[0031] In actual reactions, in order to ensure uniform contact of the reaction raw materials, the raw materials need to be stirred so that they are fully mixed and in contact. However, enzymes are proteins, and their structure is crucial to maintaining their catalytic activity. Although stirring can fully mix and contact the raw materials, the shear force generated during stirring may cause changes in the structure of the enzyme, thereby affecting its activity.

[0032] The reaction raw materials are injected into the temperature-controlled reaction equipment body 5. During the reaction, the rotating assembly 3 is used to drive the rotating cross frame 4 to reciprocate. When the equipment reciprocates, the raw materials tend to maintain their original motion state due to inertia. At the same time, the centrifugal force will move the raw materials to the edge of the equipment. During the reciprocating rotation, the inertia and centrifugal force are constantly changing, causing the raw materials to flow back and forth and exchange between different positions, thereby achieving mixing. Compared with stirring, reciprocating rotation for mixing the raw materials can reduce shear force and reduce the risk of direct damage to the enzyme structure;

[0033] When the temperature-controlled reaction equipment body 5 rotates, the shaking component 6, the push-pull component 7 and the connecting component 8 cooperate to make the temperature-controlled reaction equipment body 5 shake continuously. The reciprocating rotation of the temperature-controlled reaction equipment body 5 causes the raw materials to move in a plane. The reciprocating shaking introduces movement perpendicular to the rotation plane, causing the raw materials to shift and exchange in more directions, thereby more comprehensively disrupting the distribution of the raw materials and improving the uniformity of mixing. In addition, movement in more directions increases the chances of collision and contact between the raw material molecules, which helps molecular diffusion and accelerates the mixing of different components.

[0034] like Figures 1 to 3 As shown, the rotating assembly 3 includes a support seat 31 arranged at the bottom of the rotating cross frame 4, the support seat 31 is fixed to the top of the machine base 2, a guide groove 32 is opened on the outer side of the top of the support seat 31, and guide blocks 33 are fixed at the front and rear ends of the bottom of the rotating cross frame 4. The guide blocks 33 are placed in the guide groove 32, and a rotating column 35 is fixed at the middle position of the bottom of the rotating cross frame 4. The rotating column 35 runs through the middle position inside the support seat 31, and a motor 34 is installed at the bottom end of the machine base 2. The rotating shaft at the top of the motor 34 is fixedly connected to the bottom of the rotating column 35. The size of the guide groove 32 matches the size of the guide block 33, and the guide block 33 can rotate in the guide groove 32.

[0035] The reaction raw materials are injected into the temperature-controlled reaction equipment body 5. During the reaction, the motor 34 is started. The motor 34 drives the rotating cross frame 4 to reciprocate around the rotating column 35 by driving the rotating column 35. The rotating rotating cross frame 4 drives the temperature-controlled reaction equipment body 5 at both ends of the top to reciprocate. When the temperature-controlled reaction equipment body 5 reciprocates, the raw materials tend to maintain their original motion state due to inertia. At the same time, the centrifugal force will cause the raw materials to move to the edge of the temperature-controlled reaction equipment body 5. During the reciprocating rotation, the inertia and centrifugal force are constantly changing, causing the raw materials to flow back and forth and exchange between different positions, thereby achieving mixing. Compared with stirring, reciprocating rotation to mix the raw materials can reduce shear force and reduce the risk of direct damage to the enzyme structure.

[0036] When the rotating horizontal frame 4 reciprocates, the guide block 33 at its bottom slides inside the guide groove 32. The guide groove 32 and the guide block 33 can guide the reciprocating rotation of the rotating horizontal frame 4 to improve the stability of the reciprocating rotation of the temperature-controlled reaction equipment body 5.

[0037] like Figures 1 to 6As shown, the shaking assembly 6 includes supporting side frames 61 arranged on both sides of the temperature-controlled reaction equipment body 5, the bottom of the supporting side frames 61 is fixedly connected to the top of the rotating cross frame 4, a connecting groove 62 is opened inside the supporting side frames 61, a connecting block 63 is arranged inside the connecting groove 62, the connecting block 63 is fixed to both sides of the temperature-controlled reaction equipment body 5, a hinge block 65 is fixed at the bottom of the temperature-controlled reaction equipment body 5, a hinge seat 64 is arranged at the bottom of the hinge block 65, the bottom of the hinge seat 64 is fixedly connected to the top of the rotating cross frame 4, the hinge seat 64 is hinged to the hinge block 65, the size of the connecting groove 62 matches the size of the connecting block 63, and the connecting block 63 can slide inside the connecting groove 62.

[0038] When the temperature control reaction device body 5 rotates, the push-pull assembly 7 and the connecting assembly 8 push and pull the top of the temperature control reaction device body 5 back and forth. Since the bottom of the temperature control reaction device body 5 is hinged to the top of the rotating cross frame 4 through the hinge seat 64 and the hinge block 65, when the push-pull assembly 7 and the connecting assembly 8 push and pull the temperature control reaction device body 5 back and forth, the temperature control reaction device body 5 keeps shaking. The reciprocating rotation of the temperature control reaction device body 5 causes the raw materials to move in a plane. The reciprocating shaking introduces movement perpendicular to the rotation plane, causing the raw materials to be displaced and exchanged in more directions, thereby more comprehensively disrupting the distribution of the raw materials and improving the uniformity of mixing. In addition, movement in more directions increases the collision and contact opportunities between the raw material molecules, which helps the molecular diffusion and accelerates the mixing of different components.

[0039] When the temperature-controlled reaction equipment body 5 is shaking, the connecting blocks 63 on both sides thereof continuously slide in the connecting grooves 62, and cooperate with the connecting grooves 62 and the connecting blocks 63 to guide the reciprocating shaking of the temperature-controlled reaction equipment body 5, so as to improve the stability of the reciprocating shaking of the temperature-controlled reaction equipment body 5.

[0040] like Figures 1 to 7As shown, the push-pull assembly 7 includes a bracket 71 arranged at the front end and the rear end of the rotating horizontal frame 4, the two sides of the bracket 71 are fixedly connected to the supporting side frame 61, the bracket 71 is internally rotatably provided with a rotating rod 72, the bottom of the bracket 71 is provided with a gear 1 73, the top of the gear 1 73 is fixedly connected to the bottom of the rotating rod 72, the outside of the machine base 2 is fixed with a gear ring 75, the gear ring 75 is meshed with the gear 1 73, the top of the bracket 71 is provided with a push-pull frame 74, the inside of the push-pull frame 74 is provided with a gear 2 76, the bottom of the gear 2 76 It is fixedly connected to the top of the rotating rod 72, and the gear 2 76 is a half-tooth design. Internal teeth are provided on both sides of the push-pull frame 74. The push-pull assembly 7 also includes side blocks 77 arranged on both sides of the push-pull frame 74. The side blocks 77 are fixed to both sides of the top of the bracket 71. A limiting groove 78 is provided inside the side block 77, and a limiting block 79 is provided inside the limiting groove 78. The limiting block 79 is fixed on both sides of the push-pull frame 74. The size of the limiting groove 78 matches the size of the limiting block 79, and the limiting block 79 can slide inside the limiting groove 78.

[0041] The bracket 71 is fixed on the supporting side frame 61. When the rotating cross frame 4 drives the temperature control reaction equipment body 5 to rotate back and forth, the gear 1 73 rotates on the outside of the gear ring 75. The gear 1 73 is rotated by the gear ring 75. The gear 1 73 drives the gear 2 76 to rotate through the rotating rod 72. Since the gear 2 76 is a semi-tooth design, when the toothed part of the gear 2 76 meshes with the toothed part on one side of the push-pull frame 74, the push-pull frame 74 is pushed to move in one direction. When the toothed part of the gear 2 76 meshes with the toothed part on the other side of the push-pull frame 74, the push-pull frame 74 is pushed to move in the opposite direction. In this way, the push-pull frame 74 can be reciprocated. The reciprocating push-pull frame 74 cooperates with the connecting component 8 to reciprocately push and pull the top of the temperature control reaction equipment body 5, so that the temperature control reaction equipment body 5 can be reciprocated.

[0042] When the push-pull frame 74 moves back and forth, it will drive the limit blocks 79 on both sides of the push-pull frame 74 to slide in the limit grooves 78. The limit grooves 78 and the limit blocks 79 can guide the push-pull frame 74, so that the push-pull frame 74 can move back and forth stably.

[0043] like Figures 1 to 6 As shown, the connecting assembly 8 includes an articulated seat three 84 fixed at the middle position of the top of the temperature-controlled reaction equipment body 5, the top of the articulated seat three 84 is hinged with a push-pull rod 83, the top of the push-pull rod 83 is hinged with an articulated seat two 82, the end of the articulated seat two 82 is fixed with a connecting column 81, and one end of the connecting column 81 is fixedly connected to the end of the push-pull frame 74.

[0044] When the push-pull frame 74 moves back and forth, the push-pull frame 74 will push and pull the connecting column 81. Since a hinge seat 3 84 is fixed to the top of the temperature-controlled reaction equipment main body 5, and a hinge seat 2 82 is fixed to the end of the connecting column 81, the hinge seat 2 82 is connected to the hinge seat 3 84 through a push-pull rod 83. When the push-pull frame 74 is pushed forward through the connecting column 81, the push-pull rod 83 pushes the top of the temperature-controlled reaction equipment main body 5 to tilt. When the push-pull frame 74 is pulled back through the connecting column 81, the push-pull rod 83 pulls the top of the temperature-controlled reaction equipment main body 5 to tilt. This reciprocating motion can be used to tilt the temperature-controlled reaction equipment main body 5 in cooperation with the shaking component 6.

[0045] The above shows and describes the basic principles, main features and advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A biological enzyme temperature control reaction device, comprising a base (1), a machine base (2) fixed on the top of the base (1), a rotating horizontal frame (4) arranged at the top of the machine base (2), and a temperature control reaction device body (5) arranged at the front and rear of the top of the rotating horizontal frame (4), Features: A rotating assembly (3) is provided at the bottom of the rotating cross frame (4), shaking assemblies (6) are provided on both sides of the temperature-controlled reaction equipment body (5), push-pull assemblies (7) are provided at the front and rear ends of the rotating cross frame (4), and a connecting assembly (8) is provided at the top of the temperature-controlled reaction equipment body (5); The rotating assembly (3) comprises a support seat (31) arranged at the bottom of the rotating cross frame (4), the support seat (31) is fixed to the top of the machine base (2), a guide groove (32) is provided on the outer side of the top of the support seat (31), guide blocks (33) are fixed at the front and rear ends of the bottom of the rotating cross frame (4), the guide blocks (33) are placed in the guide groove (32), a rotating column (35) is fixed at the middle position of the bottom of the rotating cross frame (4), the rotating column (35) passes through the middle position of the inside of the support seat (31), a motor (34) is installed at the bottom end of the inside of the machine base (2), and a rotating shaft at the top of the motor (34) is fixedly connected to the bottom of the rotating column (35); The shaking assembly (6) comprises supporting side frames (61) arranged on both sides of the temperature-controlled reaction equipment body (5), the bottom of the supporting side frames (61) being fixedly connected to the top of the rotating horizontal frame (4), a connecting groove (62) being provided inside the supporting side frames (61), a connecting block (63) being provided inside the connecting groove (62), the connecting block (63) being fixed to both sides of the temperature-controlled reaction equipment body (5), a hinge block (65) being fixed at the bottom of the temperature-controlled reaction equipment body (5), a hinge seat 1 (64) being provided at the bottom of the hinge block (65), the bottom of the hinge seat 1 (64) being fixedly connected to the top of the rotating horizontal frame (4), and the hinge seat 1 (64) being hinged to the hinge block (65); The push-pull assembly (7) comprises a bracket (71) arranged at the front end and the rear end of the rotating horizontal frame (4), the two sides of the bracket (71) are fixedly connected to the supporting side frame (61), a rotating rod (72) is rotatably arranged inside the bracket (71), a gear 1 (73) is arranged at the bottom of the bracket (71), the top of the gear 1 (73) is fixedly connected to the bottom of the rotating rod (72), a gear ring (75) is fixed on the outside of the machine base (2), the gear ring (75) is meshed with the gear 1 (73), a push-pull frame (74) is arranged on the top of the bracket (71), a gear 2 (76) is arranged inside the push-pull frame (74), and the bottom of the gear 2 (76) is fixedly connected to the top of the rotating rod (72); Gear 2 (76) is of half-tooth design, and both sides of the push-pull frame (74) are provided with internal teeth; The connection assembly (8) comprises an articulated seat three (84) fixed at the middle position of the top of the temperature-controlled reaction equipment body (5); a push-pull rod (83) is hingedly connected to the top of the articulated seat three (84); the top of the push-pull rod (83) is hingedly connected to an articulated seat two (82); a connecting column (81) is fixedly connected to the end of the articulated seat two (82); one end of the connecting column (81) is fixedly connected to the end of the push-pull frame (74).

2. A biological enzyme temperature control reaction equipment according to claim 1, Features: The size of the guide groove (32) matches the size of the guide block (33), and the guide block (33) can rotate in the guide groove (32).

3. A biological enzyme temperature control reaction equipment according to claim 1, Features: The size of the connecting groove (62) matches the size of the connecting block (63), and the connecting block (63) can slide inside the connecting groove (62).

4. A biological enzyme temperature control reaction equipment according to claim 1, Features: The push-pull assembly (7) further comprises side blocks (77) arranged on both sides of the push-pull frame (74); the side blocks (77) are fixed to both sides of the top of the bracket (71); a limiting groove (78) is provided inside the side blocks (77); a limiting block (79) is provided inside the limiting groove (78); and the limiting block (79) is fixed to both sides of the push-pull frame (74).

5. A biological enzyme temperature control reaction equipment according to claim 4, Features: The size of the limiting groove (78) matches the size of the limiting block (79), and the limiting block (79) can slide inside the limiting groove (78).

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