Sample preparation and detection device in liver cancer biopsy operation

Abstract

The invention relates to the technical field of sample preparation and detection, and provides a liver cancer biopsy intraoperative sample preparation and detection device which comprises a device shell, a first protective door and a second protective door are installed on the device shell, a multifunctional processing assembly is installed in the device shell, and an efficient detection assembly is installed in the device shell. A through groove is formed in the device shell in a penetrating mode, a second threaded rod is rotationally connected to the device shell, a mounting frame is in threaded connection to the second threaded rod, a third threaded rod is rotationally connected to the mounting frame, a mounting plate is in threaded connection to the third threaded rod, and a microscope is mounted on the mounting plate. By means of the technical scheme, the problems that in the prior art, a sample preparation detection device cannot automatically and stably dye, clean and dry a plurality of liver tissue slices at the same time, and cannot conveniently and efficiently conduct pathological detection on the liver tissue slices are solved.

Description

Technical Field

[0001] The present invention relates to the technical field of specimen preparation and detection, and in particular to a specimen preparation and detection device during liver cancer biopsy. Background Art

[0002] Liver cancer is a malignant tumor with a relatively high incidence and great harm in clinical practice. When conducting clinical diagnosis on patients, they need to go to the imaging department or the radiological intervention department to accurately locate the site of the liver tumor through image-guided technology (such as CT). Then, the patient will undergo a puncture biopsy to collect samples of diseased tissue, and the liver tissue samples will be sliced ​​and sampled for pathological testing.

[0003] Since liver cancer may have many different subtypes (such as hepatocellular carcinoma, cholangiocarcinoma, etc.), and different tissue regions may show different changes, it is necessary to take multiple samples from different areas of the patient's liver tumor site to ensure full representativeness. However, the existing specimen preparation and detection device cannot automatically and stably stain, clean and dry multiple liver tissue sections at the same time during operation, and cannot perform convenient and efficient pathological detection on multiple liver tissue sections. It has poor practicality and low work efficiency. In order to avoid the problem that repeated use of the same stain for multiple liver tissue sections will cause cross contamination, affect the staining effect between different sections, and even affect the final diagnosis result, the stain is generally disposable, and the existing specimen preparation and detection device cannot automatically load and unload the stain and detergent during actual operation. Therefore, when preparing multiple liver tissue sections, the staff needs to repeatedly load and unload the stain and detergent, which is time-consuming and labor-intensive. Therefore, it is necessary to provide a liver cancer biopsy intraoperative specimen preparation and detection device to meet the needs of users. Summary of the invention

[0004] The present invention proposes a specimen preparation and detection device for liver cancer biopsy surgery, which solves the problems that the specimen preparation and detection device in the related art cannot automatically and stably stain, clean and dry multiple liver tissue sections at the same time, cannot perform convenient and efficient pathological detection on multiple liver tissue sections, and cannot automatically load and unload dyes and cleaning agents.

[0005] The technical solution of the present invention is as follows: A sample preparation and detection device for liver cancer biopsy, comprising a device shell, a first protective door and a second protective door are installed on the device shell, a multifunctional processing component is installed in the device shell, a high-efficiency detection component is installed in the device shell, a through slot is opened through the device shell, a second threaded rod is rotatably connected to the device shell, a mounting frame is threadedly connected to the second threaded rod, a third threaded rod is rotatably connected to the mounting frame, a mounting plate is threadedly connected to the third threaded rod, a microscope is installed on the mounting plate, a first magnetic frame is attached to the top outer wall of the device shell, a fill light is installed on the inner wall of the device shell, the multifunctional processing component comprises a sliding plate, the sliding plate is limitedly slidably connected in the device shell, a card slot is opened on the sliding plate, a reset spring is welded and fixed on the device shell, a card rod is welded and fixed at the end of the reset spring, the end of the card rod is card-engaged in the card slot, a processing frame and a liquid storage tank are welded and fixed on the top surface of the sliding plate, and a push rod is welded and fixed on the processing frame.

[0006] As a preferred solution of the present invention, there are two processing frames and two card slots, which are symmetrically distributed on the left and right sides of the sliding plate, and the liquid storage tanks are symmetrically distributed on the front and back sides of the processing frames.

[0007] As a preferred solution of the present invention, wherein: a guide tube is fixedly connected to the liquid storage tank, one end of the guide tube is connected to the side end of the processing frame, the other end of the guide tube is fixedly connected to a conveying cylinder, a spiral rod is rotatably connected to the conveying cylinder, the spiral rod is rotatably connected to the liquid storage tank, a coil is fixedly connected to the spiral rod, a first traction rope is wound around the coil, an end of the first traction rope is fixedly connected to the device housing, the length of the spiral rod is greater than the length of the conveying cylinder, and the spiral rod is connected to the middle part inside the device housing.

[0008] As a preferred scheme of the present invention, wherein: a limited position frame is welded and fixed in the liquid storage tank, a spiral spring is welded and fixed in the limited position frame, the inner end of the spiral spring is welded and fixed to the top of the spiral rod, a fixing rod is welded and fixed to the bottom of the spiral rod, a stirring rod is welded and fixed on the fixing rod, a first discharge pipe is connected to the middle part of the bottom of the processing frame, a second discharge pipe is connected to the bottom of the device shell, the top end surface of the first discharge pipe is flush with the inner bottom end surface of the processing frame, the bottom end surface of the first discharge pipe is flush with the bottom end surface of the processing frame, the second discharge pipe is symmetrically distributed on both sides of the bottom of the device shell, the top end surface of the second discharge pipe is flush with the top end surface of the device shell, and the diameter of the second discharge pipe is larger than the diameter of the first discharge pipe.

[0009] As a preferred solution of the present invention, wherein: the high-efficiency detection component includes a hydraulic rod, the hydraulic rod is installed and fixed on the top of the device housing, the bottom end of the hydraulic rod is fixedly connected to a fixing plate, a small motor is installed and fixed on the fixing plate, a rotating rod is welded and fixed on the output shaft of the small motor, a shift rod is welded and fixed at one end of the rotating rod, a first limit plate is welded and fixed at the other end of the rotating rod, a driven shaft is rotatably connected to the fixed plate, a connecting frame and a support plate are welded and fixed on the driven shaft, and a guide frame and a second limit plate are welded and fixed in the connecting frame.

[0010] As a preferred solution of the present invention, wherein: the driven shaft is connected to the center part of the connecting frame and the support plate, the support plate is in a "cross" shape as a whole, four guide frames and four second limit plates are provided, four guide frames and four second limit plates are evenly distributed in the connecting frame at equal angles, the guide frames and the second limit plates are alternately distributed, and the first limit plate and the second limit plate are both arc-shaped.

[0011] As a preferred solution of the present invention, wherein: the bottom of the support plate is rotatably connected to a rotating shaft, a first bevel gear is welded and fixed on the rotating shaft, a second bevel gear is meshingly connected to the first bevel gear, the rotating shaft is connected to the center of the bottom of the support plate, four second bevel gears are provided, and the four second bevel gears are equiangularly distributed on the first bevel gear, a first threaded rod is welded and fixed on the second bevel gear, the first threaded rod is rotatably connected in the support plate, and a first clamping plate is threadedly connected to the first threaded rod.

[0012] As a preferred solution of the present invention, wherein: a connecting plate is welded and fixed on the supporting plate, a sliding rod is slidably connected to the connecting plate, a second clamping plate is welded and fixed to one end of the sliding rod, the other end of the sliding rod is fixedly connected to the second traction rope, the second traction rope is slidably connected to the connecting plate, the end of the second traction rope is fixedly connected to the third clamping plate, one end of the third clamping plate is limitedly slidably connected to the connecting plate, a connecting spring is welded and fixed on the third clamping plate, the other end of the connecting spring is welded and fixed in the connecting plate, four connecting plates are provided, and the four connecting plates are equiangularly distributed around the supporting plate, the sliding rod is connected to the middle part of the connecting plate, the second traction rope is symmetrically distributed on both sides of the sliding rod, and the second traction rope corresponds one-to-one with the connecting spring through the third clamping plate.

[0013] As a preferred solution of the present invention, the bottom end surface of the mounting frame is in contact with the outer wall of the device housing, the third threaded rod is connected to the middle part of the mounting plate, the fill light is symmetrically distributed on both sides of the device housing, and the mounting plate is limitedly slidably connected to the mounting frame.

[0014] The working principle and beneficial effects of the present invention are: 1. The present invention is provided with a multifunctional processing component, which utilizes the engagement and positioning of the card slot and the card rod, and can conveniently and stably switch the positions of the processing frames on both sides by pushing the sliding plate through the push rod, so that the liver tissue sections can be stained and cleaned in turn, thereby ensuring the convenience and efficiency of the subsequent detection of the liver tissue sections; and in the process of position switching of the processing frames on both sides, under the traction of the first traction rope, the combined coil can drive the spiral rod to rotate automatically, so that the dye or cleaning agent can be automatically transported to the inside of the processing frames on both sides, and when the processing frame moves and resets, the used dye or cleaning agent can be automatically discharged through the first discharge pipe and the second discharge pipe, completing the automatic loading and unloading of the dye or cleaning agent, effectively improving the automation degree of the specimen sample preparation and detection device, and thus improving the working efficiency of the specimen sample preparation and detection device.

[0015] 2. The present invention is provided with an efficient detection component, which utilizes the second bevel gears on the first bevel gear to drive the first threaded rods to rotate simultaneously, and then drive the first clamping plates to move toward the corresponding second clamping plates at the same time. At this time, the first clamping plates are combined with the corresponding second clamping plates and the third clamping plates to simultaneously complete the all-round clamping, fixing and positioning of multiple glass slides, thereby ensuring the stability of subsequent staining, cleaning, drying and detection of liver tissue sections on the glass slides. In addition, by clamping and positioning multiple glass slides at the same time, combined with the multifunctional processing component, the staining, cleaning and drying of multiple liver tissue sections can be completed in batches, further improving the working efficiency of the specimen preparation and detection device.

[0016] 3. The present invention is provided with a mounting plate and a connecting frame. The threaded rotation of the second threaded rod and the third threaded rod can drive the microscope to perform convenient and stable position adjustment, thereby ensuring the convenience and accuracy of subsequent detection work; and the continuous movement of the lever combined with the second limit plate can drive the connecting frame to perform automatic and stable intermittent rotation, and each rotation is 90°, so that the four slides on the support plate can be driven to move one by one to the bottom of the microscope through the driven shaft, thereby completing the detection of multiple liver tissue sections conveniently and stably, and the continuous equal-angle rotation of the support plate can ensure that each cleaned liver tissue section can be dried efficiently and evenly, thereby increasing the diversity and convenience of the specimen preparation and detection device. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0018] Figure 1 It is a schematic diagram of the overall three-dimensional structure of the present invention; Figure 2 It is a schematic diagram of the main cross-sectional structure of the housing of the device of the present invention; Figure 3 The present invention Figure 2 The enlarged structural diagram at A in the middle; Figure 4 It is a schematic diagram of the side cross-sectional structure of the housing of the device of the present invention; Figure 5 The present invention Figure 4 The enlarged structural diagram at B in the middle; Figure 6 It is a schematic diagram of the top-sectional structure of the housing of the device of the present invention; Figure 7 It is a schematic diagram of the top view of the spiral spring of the present invention; Figure 8 It is a schematic diagram of the main cross-sectional structure of the support plate of the present invention; Fig. 9 It is a schematic diagram of the main cross-sectional structure of the connecting frame of the present invention; Fig.10 It is a schematic diagram of the top view of the connecting frame of the present invention; Fig.11 is a schematic diagram of a top view of the structure of a second bevel gear of the present invention; Fig.12 It is a schematic diagram of the top view of the support plate of the present invention; Fig.13 It is a schematic diagram of the main cross-sectional structure of the connecting plate of the present invention; Fig.14 It is a schematic diagram of the top-sectional structure of the connection plate of the present invention; Fig.15 It is a schematic diagram of the main cross-sectional structure of the thermal insulation box of the present invention; Fig.16 It is a schematic diagram of the main cross-sectional structure of the mounting plate of the present invention; Fig.17 It is a schematic diagram of the side structure of the mounting frame of the present invention.

[0019] In the figure: 1. device housing; 2. first protective door; 3. second protective door; 4. multifunctional processing component; 401. sliding plate; 402. card slot; 403. reset spring; 404. card rod; 405. processing frame; 406. liquid storage tank; 407. guide tube; 408. conveying cylinder; 409. spiral rod; 410. coil; 411. first traction rope; 412. limit frame; 413. volute spring; 414. fixed rod; 415. stirring rod; 416. first discharge pipe; 417. second discharge pipe; 418. push rod; 5. high-efficiency detection component; 501. hydraulic rod; 502. fixed plate; 503. small motor; 504. rotating rod; 505. lever; 506. first limit plate; 507. driven shaft; 508. connecting frame ; 509, guide frame; 510, second limit plate; 511, support plate; 512, rotating shaft; 513, first bevel gear; 514, second bevel gear; 515, first threaded rod; 516, first clamping plate; 517, connecting plate; 518, sliding rod; 519, second clamping plate; 520, second traction rope; 521, third clamping plate; 522, connecting spring; 523, rubber pad; 6, through groove; 7, second threaded rod; 8, mounting frame; 9, third threaded rod; 10, mounting plate; 11, microscope; 12, first magnetic frame; 13, fill light; 14, air pump; 15, first connecting pipe; 16, temperature insulation box; 17, second connecting pipe; 18, filter frame; 19, activated carbon mesh; 20, second magnetic frame; 21, electric heating plate. DETAILED DESCRIPTION

[0020] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] Embodiment 1, as Figure 1 to Figure 17As shown, this embodiment proposes a liver cancer biopsy intraoperative specimen preparation and detection device, including a device housing 1, a first protective door 2 and a second protective door 3 are installed on the device housing 1, a multifunctional processing component 4 is installed in the device housing 1, a high-efficiency detection component 5 is installed in the device housing 1, a through groove 6 is opened through the device housing 1, a second threaded rod 7 is rotatably connected to the device housing 1, a mounting frame 8 is threadedly connected to the second threaded rod 7, a third threaded rod 9 is rotatably connected to the mounting frame 8, a mounting plate 10 is threadedly connected to the third threaded rod 9, and a display is installed on the mounting plate 10 The micromirror 11 and the top outer wall of the device housing 1 are attached with a first magnetic frame 12, and the inner wall of the device housing 1 is installed with a fill light 13. The high-efficiency detection component 5 can simultaneously complete the full-dimensional clamping, fixing and positioning of multiple glass slides, thereby ensuring the stability of subsequent staining, cleaning, drying and detection of liver tissue sections on the glass slides. In addition, by clamping and positioning multiple glass slides at the same time, combined with the multifunctional processing component 4, the staining, cleaning and drying of multiple liver tissue sections can be completed in batches, thereby further improving the working efficiency of the specimen preparation and detection device.

[0022] Embodiment 2, as Figure 1 to Figure 17 As shown, based on the same concept as the above-mentioned embodiment 1, this embodiment also proposes a liver cancer biopsy intraoperative specimen preparation and detection device.

[0023] In this embodiment, an air pump 14 is fixedly installed on the device housing 1, and a first connecting pipe 15 is flange-connected to the air pump 14. One end of the first connecting pipe 15 is fixedly connected to the device housing 1, and the other end of the first connecting pipe 15 is connected to a thermal insulation box 16. A second connecting pipe 17 is connected to the bottom of the thermal insulation box 16, and the second connecting pipe 17 is fixedly connected to the device housing 1. A filter frame 18 and an activated carbon mesh plate 19 are slidably connected through the thermal insulation box 16, and a second magnetic frame 20 is magnetically adsorbed and connected to the top of the thermal insulation box 16. An electric heating plate 21 is installed in the thermal insulation box 16. With the cooperation of the first connecting pipe 15 and the second connecting pipe 17 on the thermal insulation box 16, the circulation of air inside the device can be completed, and the air can be heated by the electric heating plate 21, so that the cleaned liver tissue slices can be dried to ensure the accuracy of subsequent detection work.

[0024] In this embodiment, the multifunctional processing component 4 includes a sliding plate 401, which is limitedly slidably connected in the device housing 1, and a card slot 402 is provided on the sliding plate 401. A reset spring 403 is welded and fixed on the device housing 1, and a clamping rod 404 is welded and fixed at the end of the reset spring 403. The clamping rod 404 penetrates and slides in the device housing 1, and the end of the clamping rod 404 is clamped and connected in the card slot 402. A processing frame 405 and a liquid storage tank 406 are welded and fixed on the top surface of the sliding plate 401, and a Push rod 418, push rod 418 penetrates and is slidably connected to the device housing 1, two processing frames 405 and two card slots 402 are provided, the two processing frames 405 and the two card slots 402 are symmetrically distributed on the left and right sides of the sliding plate 401, and the liquid storage tank 406 is symmetrically distributed on the front and back sides of the processing frame 405. By utilizing the engagement and positioning of the card slot 402 and the card rod 404, the sliding plate 401 can be pushed by the push rod 418 to conveniently and stably switch the positions of the processing frames 405 on both sides, so that the liver tissue sections can be stained and cleaned in turn.

[0025] In this embodiment, a guide tube 407 is fixedly connected to the liquid storage tank 406, one end of the guide tube 407 is connected to the side end of the processing frame 405, and the other end of the guide tube 407 is fixedly connected to a conveying cylinder 408, and a spiral rod 409 is rotatably connected to the conveying cylinder 408, and the spiral rod 409 is rotatably connected to the liquid storage tank 406, and a coil 410 is fixedly connected to the spiral rod 409, and a first traction rope 411 is wound around the coil 410, and the first traction rope 411 penetrates and slides in the liquid storage tank 406. The end of 411 is fixedly connected to the device housing 1, the length of the spiral rod 409 is greater than the length of the conveying cylinder 408, the spiral rod 409 is connected to the middle part of the device housing 1, the limited position frame 412 is welded and fixed in the liquid storage tank 406, and a spiral spring 413 is welded and fixed in the limited position frame 412. The inner end of the spiral spring 413 is welded and fixed to the top of the spiral rod 409, and a fixing rod 414 is welded and fixed to the bottom of the spiral rod 409. A stirring rod 415 is welded and fixed to the fixing rod 414. The middle of the bottom of the processing frame 405 The first feeding tube 416 is connected to the upper part of the device housing 1, and the second feeding tube 417 is connected to the bottom of the device housing 1. Solenoid valves are installed on the first feeding tube 416 and the second feeding tube 417. The top end surface of the first feeding tube 416 is flush with the inner bottom end surface of the processing frame 405, and the bottom end surface of the first feeding tube 416 is flush with the bottom end surface of the processing frame 405. The second feeding tube 417 is symmetrically distributed on both sides of the bottom of the device housing 1. The top end surface of the second feeding tube 417 is flush with the top end surface of the device housing 1. The straightness of the second feeding tube 417 The diameter is larger than the diameter of the first discharge pipe 416. During the position switching of the processing frames 405 on both sides, under the traction of the first traction rope 411, the combined coil 410 can drive the spiral rod 409 to rotate automatically, and then can automatically transport the dye or cleaning agent to the inside of the processing frames 405 on both sides, and when the processing frame 405 moves to reset, the used dye or cleaning agent can be automatically discharged through the first discharge pipe 416 and the second discharge pipe 417, completing the automatic loading and unloading of the dye or cleaning agent.

[0026] In this embodiment, the high-efficiency detection component 5 includes a hydraulic rod 501, which is installed and fixed on the top of the device housing 1, and the bottom end of the hydraulic rod 501 is fixedly connected to a fixed plate 502, and a small motor 503 is installed and fixed on the fixed plate 502. A rotating rod 504 is welded and fixed on the output shaft of the small motor 503, and a shift rod 505 is welded and fixed on one end of the rotating rod 504. A first limiting plate 506 is welded and fixed on the other end of the rotating rod 504, and a driven shaft 507 is rotatably connected to the fixed plate 502, and a connecting frame 508 and a support plate 511 are welded and fixed on the driven shaft 507. A guide frame 509 and a second limiting plate 510 are welded and fixed in the connecting frame 508, and the driven shaft 507 is connected to the center of the connecting frame 508 and the support plate 511. The support plate 511 is in a "cross" shape as a whole, and four guide frames 509 and four second limit plates 510 are provided. The four guide frames 509 and the four second limit plates 510 are evenly distributed in the connecting frame 508, and the guide frames 509 and the second limit plates 510 are alternately distributed. The first limit plate 506 and the second limit plate 510 are both arc-shaped. The support plate 511 is made of transparent material, and the continuous movement of the lever 505 combined with the second limit plate 510 can drive the connecting frame 508 to rotate intermittently automatically and stably, and each time it rotates 90°, and then the four slides on the support plate 511 can be driven by the driven shaft 507 to move one by one to the bottom of the microscope 11, so that the detection of multiple liver tissue sections can be completed conveniently and stably.

[0027] In this embodiment, the bottom of the support plate 511 is rotatably connected to a rotating shaft 512, a first bevel gear 513 is welded and fixed on the rotating shaft 512, a second bevel gear 514 is meshed and connected to the first bevel gear 513, the rotating shaft 512 is connected to the center of the bottom of the support plate 511, four second bevel gears 514 are provided, and the four second bevel gears 514 are distributed on the first bevel gear 513 at equal angles, a first threaded rod 515 is welded and fixed on the second bevel gear 514, and the first threaded rod 515 is rotatably connected to the support plate 511. The first threaded rod 515 is connected to the support plate 511, and the first clamping plate 516 is threadedly connected to the first threaded rod 515. The support plate 511 is welded and fixed with a connecting plate 517. The connecting plate 517 is slidably connected with a sliding rod 518. One end of the sliding rod 518 is welded and fixed with a second clamping plate 519. The other end of the sliding rod 518 is fixedly connected with a second traction rope 520. The second traction rope 520 is slidably connected to the connecting plate 517. The end of the second traction rope 520 is fixedly connected with a third clamping plate 521. One end is limitedly slidably connected in the connecting plate 517, a connecting spring 522 is welded and fixed on the third clamping plate 521, and the other end of the connecting spring 522 is welded and fixed in the connecting plate 517. The first clamping plate 516, the second clamping plate 519 and the third clamping plate 521 are all provided with rubber pads 523. Four connecting plates 517 are provided, and the four connecting plates 517 are distributed around the supporting plate 511 at equal angles. The sliding rod 518 is connected to the middle part of the connecting plate 517, and the second traction rope 520 is symmetrically distributed on the sliding rod 51 On both sides of 8, the second traction ropes 520 correspond to the connecting springs 522 one by one through the third clamping plates 521, and the second bevel gears 514 on the first bevel gear 513 can drive the first threaded rods 515 to rotate at the same time, thereby driving the first clamping plates 516 to move toward the corresponding second clamping plates 519 at the same time. At this time, the first clamping plates 516 are combined with the corresponding second clamping plates 519 and the third clamping plates 521 to complete the full-scale clamping, fixing and positioning of multiple slides at the same time.

[0028] In this embodiment, the bottom end surface of the mounting bracket 8 is fitted with the outer wall of the device housing 1, the third threaded rod 9 is connected to the middle part of the mounting plate 10, the fill light 13 is symmetrically distributed on both sides of the device housing 1, and the mounting plate 10 is slidingly connected to the mounting bracket 8. By utilizing the threaded rotation of the second threaded rod 7 and the third threaded rod 9, the microscope 11 can be driven to perform convenient and stable position adjustment, thereby ensuring the convenience and accuracy of subsequent detection work.

[0029] It should be noted that the present invention is a specimen preparation and detection device for liver cancer biopsy. First, a feeding pipe is provided on the liquid storage tank 406. The staff can transport dyes to the inside of the two liquid storage tanks 406 on the left and transport cleaning agents to the inside of the two liquid storage tanks 406 on the right by opening the first protective door 2 on the device shell 1. In the initial state, the two liquid storage tanks 406 on the left are located at the leftmost part of the device shell 1, and the two liquid storage tanks 406 on the right are located in the middle part of the device shell 1. The staff can take biopsy samples from different areas of the patient's liver and slice them, and lay liver tissue slices from four different areas on four glass slides respectively. Then the staff can open the second protective doors 3 on both sides of the device shell 1, and place the four glass slides around the support plate 511. By rotating the rotating shaft 512, the first bevel gear 513 can be driven to rotate, and then the second bevel gear 513 can be driven to rotate through four threaded connections. The gear 514 drives the corresponding first threaded rod 515 to rotate at the same time, so as to drive each threadedly connected first clamping plate 516 to move toward the corresponding second clamping plate 519. At this time, the first clamping plate 516 can push the glass slide to move toward the second clamping plate 519. Then the glass slide contacts the second clamping plate 519 first, and the glass slide continues to move. At this time, the first clamping plate 516 can push the second clamping plate 519 to move toward the connecting plate 517 through the glass slide. Under the movement of the second clamping plate 519, the second traction rope 520 on the slide bar 518 can pull the third clamping plates 521 on both sides to move toward the middle at the same time, and clamp and position the glass slide in the middle. At this time, under the joint action of each first clamping plate 516, the second clamping plate 519 and the third clamping plates 521 on both sides of the second clamping plate 519, combined with the rubber pad 523, the full-dimensional clamping, fixing and positioning of multiple glass slides can be completed at the same time. Then the staff can pull the lever 404 on the device housing 1 outwards and disengage it from the slot 402 on the right side of the sliding plate 401. At this time, the staff can use the push rod 418 to move the sliding plate 401 from left to right, thereby driving the processing frame 405 on the left side of the sliding plate 401 to be located in the middle part of the device, that is, directly below the support plate 511. At this time, the lever 404 can be released, and the lever 404 can be automatically engaged in the slot 402 on the left side of the sliding plate 401 under the elastic action of the return spring 403 for engagement and fixing; and during the movement of the sliding plate 401, the liquid storage tank 405 can be driven to move. 06 synchronous movement, at this time, under the pulling action of the first traction rope 411, the coil 410 can drive the spiral rod 409 to rotate automatically, and the dye in the liquid storage tank 406 can be automatically transported to the processing frame 405 in combination with the conveying cylinder 408 and the guide tube 407. Then, under the driving action of the hydraulic rod 501, the driven shaft 507 on the fixed plate 502 can push the support plate 511 to move downward, and drive each slide glass to be immersed in the dye in the processing frame 405, so as to perform the staining work of the liver tissue sections. After staining, the hydraulic rod 501 can be driven to drive each slide glass on the support plate 511 to move upward and reset; Then, through the same operation, the sliding plate 401 is moved from right to left, and the cleaning agent in the right liquid storage tank 406 can be automatically transported to the right processing frame 405, and then, under the driving action of the hydraulic rod 501, each stained liver tissue slice can be driven to automatically clean; and when the sliding plate 401 is moved from right to left, under the elastic action of the spiral spring 413, the coil 410 can be driven to automatically reverse, and the first traction rope 411 can be automatically reeled up to ensure the stability of the first traction rope 411 in repeated use, and after the sliding plate 401 is moved from right to left, the first discharge pipe 416 on the left processing frame 405 can be aligned with the second discharge pipe 417 on the left, so that the used dye can be automatically discharged; similarly, after the cleaning work is completed, when the sliding plate 401 is moved to the far right, the automatic discharge of the cleaning agent is also completed, and this reciprocating process can complete the automatic loading and unloading of the dye or the cleaning agent, effectively improving the working efficiency of the specimen preparation and detection device; After the liver tissue sections are stained and cleaned, the air pump 14 is driven. At this time, the air inside the device can be circulated under the cooperation of the first connecting tube 15 and the second connecting tube 17 on the temperature isolation box 16. In the process of air circulation, the filter frame 18 and the activated carbon screen plate 19 can be used to filter and purify the air, and the air can be heated by the electric heating plate 21. The heated air is transported to the slide through the first connecting tube 15 to dry the cleaned liver tissue sections to ensure the accuracy of subsequent detection work. After the device is finished working, the filter frame 18 and the activated carbon screen plate 19 can be conveniently disassembled and assembled by opening the second magnetic frame 20, ensuring the convenience of subsequent cleaning and replacement work. After the liver tissue sections are stained, washed and dried, the staff can open the first magnetic frame 12. At this time, the staff can use the second threaded rod 7 and the third threaded rod 9 to rotate the threads to drive the microscope 11 to adjust the position in the left and right and front and back directions, and the liver tissue sections on the slide can be detected through the through slot 6; and the small motor 503 on the driving plate 502 can drive the rotating rod 504 to rotate stably. At this time, the rotating rod 504 can drive the lever 505 to move into the guide frame 509 and drive the connecting frame 508 on the driven shaft 507 to rotate. During the continuous rotation of the lever 505 Under the action of movement, each guide frame 509 can drive the connecting frame 508 to perform automatic and stable intermittent rotation, and each rotation is 90°, and then the four slides on the support plate 511 can be driven to move one by one to the bottom of the microscope 11 through the driven shaft 507, so that the detection of multiple liver tissue sections can be completed conveniently and stably. Moreover, when the connecting frame 508 stops moving, the first limit plate 506 on the rotating rod 504 is in contact with the second limit plate 510 in the connecting frame 508, and the connecting frame 508 is limited to prevent the support plate 511 from shaking when it stops rotating, thereby ensuring the stability of the detection work.

[0030] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A liver cancer biopsy specimen preparation and detection device, characterized in that: The device comprises a housing (1), wherein a first protective door (2) and a second protective door (3) are installed on the housing (1), a multifunctional processing component (4) is installed in the housing (1), a high-efficiency detection component (5) is installed in the housing (1), a through slot (6) is provided through the housing (1), a second threaded rod (7) is rotatably connected to the housing (1), a mounting frame (8) is threadedly connected to the second threaded rod (7), a third threaded rod (9) is rotatably connected to the mounting frame (8), a mounting plate (10) is threadedly connected to the third threaded rod (9), a microscope (11) is installed on the mounting plate (10), and a first threaded rod (11) is attached to the top outer wall of the housing (1). A magnetic frame (12), a fill light (13) is installed on the inner wall of the device housing (1), the multifunctional processing component (4) comprises a sliding plate (401), the sliding plate (401) is limitedly slidably connected in the device housing (1), a slot (402) is provided on the sliding plate (401), a reset spring (403) is welded and fixed on the device housing (1), a clamping rod (404) is welded and fixed at the end of the reset spring (403), and the end of the clamping rod (404) is clamped and connected in the slot (402), a processing frame (405) and a liquid storage tank (406) are welded and fixed on the top surface of the sliding plate (401), and a push rod (418) is welded and fixed on the processing frame (405).

2. The liver cancer biopsy specimen preparation and detection device according to claim 1, characterized in that: The processing frames (405) and the card slots (402) are both provided in pairs, and the two processing frames (405) and the two card slots (402) are symmetrically distributed on the left and right sides of the sliding plate (401), and the liquid storage tanks (406) are symmetrically distributed on the front and back sides of the processing frames (405).

3. The liver cancer biopsy specimen preparation and detection device according to claim 2, characterized in that: A guide tube (407) is fixedly connected to the liquid storage tank (406), one end of the guide tube (407) is connected to the side end of the processing frame (405), and the other end of the guide tube (407) is fixedly connected to a conveying cylinder (408). A spiral rod (409) is rotatably connected to the conveying cylinder (408), and the spiral rod (409) is rotatably connected to the liquid storage tank (406). A coil (410) is fixedly connected to the spiral rod (409), and a first traction rope (411) is wound around the coil (410). The end of the first traction rope (411) is fixedly connected to the device housing (1). The length of the spiral rod (409) is greater than the length of the conveying cylinder (408), and the spiral rod (409) is connected to the middle part of the device housing (1).

4. The liver cancer biopsy specimen preparation and detection device according to claim 3, characterized in that: A limit frame (412) is welded and fixed inside the liquid storage tank (406), a spiral spring (413) is welded and fixed inside the limit frame (412), the inner end of the spiral spring (413) is welded and fixed to the top of the spiral rod (409), a fixing rod (414) is welded and fixed to the bottom of the spiral rod (409), a stirring rod (415) is welded and fixed to the fixing rod (414), a first discharge pipe (416) is connected to the middle part of the bottom of the processing frame (405), and the bottom of the device housing (1) is A second feed tube (417) is connected to the device housing (1), the top end surface of the first feed tube (416) is flush with the inner bottom end surface of the processing frame (405), the bottom end surface of the first feed tube (416) is flush with the bottom end surface of the processing frame (405), the second feed tube (417) is symmetrically distributed on both sides of the bottom of the device housing (1), the top end surface of the second feed tube (417) is flush with the top end surface of the device housing (1), and the diameter of the second feed tube (417) is greater than the diameter of the first feed tube (416).

5. The liver cancer biopsy specimen preparation and detection device according to claim 1, characterized in that: The high-efficiency detection component (5) comprises a hydraulic rod (501), wherein the hydraulic rod (501) is mounted and fixed on the top of the device housing (1), the bottom end of the hydraulic rod (501) is fixedly connected to a fixing plate (502), a small motor (503) is fixedly mounted on the fixing plate (502), a rotating rod (504) is welded and fixed to the output shaft of the small motor (503), a shifting rod (505) is welded and fixed to one end of the rotating rod (504), a first limiting plate (506) is welded and fixed to the other end of the rotating rod (504), a driven shaft (507) is rotatably connected to the fixing plate (502), a connecting frame (508) and a supporting plate (511) are welded and fixed to the driven shaft (507), and a guide frame (509) and a second limiting plate (510) are welded and fixed inside the connecting frame (508).

6. The liver cancer biopsy specimen preparation and detection device according to claim 5, characterized in that: The driven shaft (507) is connected to the center of the connecting frame (508) and the supporting plate (511); the supporting plate (511) is in the shape of a "cross" as a whole; four guide frames (509) and four second limit plates (510) are provided; the four guide frames (509) and the four second limit plates (510) are evenly distributed in the connecting frame (508); the guide frames (509) and the second limit plates (510) are alternately distributed; and the first limit plates (506) and the second limit plates (510) are both in the shape of circular arcs.

7. The liver cancer biopsy specimen preparation and detection device according to claim 6, characterized in that: The bottom of the support plate (511) is rotatably connected to a rotating shaft (512), a first bevel gear (513) is welded and fixed to the rotating shaft (512), a second bevel gear (514) is meshingly connected to the first bevel gear (513), the rotating shaft (512) is connected to the center of the bottom of the support plate (511), four second bevel gears (514) are provided, and the four second bevel gears (514) are distributed on the first bevel gear (513) at equal angles, a first threaded rod (515) is welded and fixed to the second bevel gear (514), the first threaded rod (515) is rotatably connected to the support plate (511), and a first clamping plate (516) is threadedly connected to the first threaded rod (515).

8. The liver cancer biopsy specimen preparation and detection device according to claim 7, characterized in that: A connecting plate (517) is welded and fixed on the supporting plate (511), a sliding rod (518) is slidably connected to the connecting plate (517), a second clamping plate (519) is welded and fixed to one end of the sliding rod (518), a second traction rope (520) is fixedly connected to the other end of the sliding rod (518), the second traction rope (520) is slidably connected to the connecting plate (517), an end of the second traction rope (520) is fixedly connected to the third clamping plate (521), and one end of the third clamping plate (521) is limitedly slidably connected to the connecting plate (519). 7), a connecting spring (522) is welded and fixed on the third clamping plate (521), and the other end of the connecting spring (522) is welded and fixed in the connecting plate (517), and the connecting plates (517) are provided with four, and the four connecting plates (517) are distributed at equal angles around the supporting plate (511), and the sliding rod (518) is connected to the middle part of the connecting plate (517), and the second traction rope (520) is symmetrically distributed on both sides of the sliding rod (518), and the second traction rope (520) corresponds to the connecting spring (522) one by one through the third clamping plate (521).

9. The liver cancer biopsy specimen preparation and detection device according to claim 1, characterized in that: The bottom end surface of the mounting frame (8) is in contact with the outer wall of the device housing (1); the third threaded rod (9) is connected to the middle part of the mounting plate (10); the fill light (13) is symmetrically distributed on both sides of the device housing (1); and the mounting plate (10) is limitedly slidably connected to the mounting frame (8).

Images