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Medicine for treating chronic conjunctivitis

A technology for chronic conjunctivitis and drugs, which can be used in pharmaceutical formulations, drug combinations, drug delivery, etc., and can solve the problems of not widely used clinically, expensive raw materials, and complex formulation components.

Inactive Publication Date: 2007-04-25
BEIJING INST OF OPHTHALMOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patient feels that the eyes are dry, itchy, and visually fatigued, which seriously affects daily life and study and work. At present, there is no good effective drug in clinical practice. Commonly used antibiotics, vitamin eye drops and astringents are used for treatment, but the curative effect is not significant. Chinese patent disclosure Through some methods of using traditional Chinese medicine to treat conjunctivitis, such as: CN1100953, CN1108556, CN1132627, CN1207322, CN89105757.9, the formulas of these patents have not been successfully used in clinical practice, and the formula components are complicated and the raw materials are expensive
Although the CN02131250.8 patent has simple prescriptions and reasonable compatibility, it has not been widely used clinically so far

Method used

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  • Medicine for treating chronic conjunctivitis

Examples

Experimental program
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Effect test

Embodiment 1

[0037] [embodiment 1] preparation of eye drops of medicine of the present invention

[0038]Add 5g of honeysuckle, 5g of astragalus and 2.5g of Fangfeng, add 20 times of distilled water to decoct and extract twice, each time for 1.5 hours, combine the decoction, filter, concentrate to a clear paste with a relative density of 1.10-1.12 (50C) , add ethanol to precipitate, filter, stand overnight, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, add distilled water to the liquid to adjust to 12.5ml, and set aside. Crush 0.5g of pearls into powder, add an appropriate amount of water to make a paste, add 1.8 times concentrated hydrochloric acid to hydrolyze to dissolve, let stand for stratification, filter, and then heat the filter residue with 15% hydrochloric acid to reflux for 24 hours, filter the hydrolyzate, combine the two The secondary hydrolyzate was heated in a water bath to drive out the acid, then the pH was adjusted...

Embodiment 2

[0039] [embodiment 2] eye ​​ointment preparation of medicine of the present invention

[0040] Add 5g of honeysuckle, 5g of astragalus, and 2.5g of Fangfeng, add 20 times of distilled water, decoct and extract twice, each time for 1.5 hours, combine the decoction, filter, and concentrate to a clear liquid with a relative density of 1.10-1.12 (50°C). Paste, add ethanol to precipitate, filter, stand overnight, filter, and recover ethanol from the filtrate under reduced pressure until it has no alcohol smell, add distilled water to adjust the liquid to 12.5ml, and set aside. Crush 0.5g of pearls into powder, add an appropriate amount of water to make a paste, add 1.8 times concentrated hydrochloric acid to hydrolyze to dissolve, let stand for stratification, filter, and then heat the filter residue with 15% hydrochloric acid to reflux for 24 hours, filter the hydrolyzate, combine the two The secondary hydrolyzate was heated in a water bath to drive out the acid, then the pH was a...

Embodiment 3

[0041] [Embodiment 3] Preparation of eye compress of medicine of the present invention

[0042] The preparation method is the same as in Example 1, under aseptic conditions, the liquid is added to the eye patch of non-woven fabric, packed into an aluminum bag and sealed to obtain final product.

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Abstract

The invention discloses a pharmaceutical composition for treating chronic conjunctivitis, which is prepared from honeysuckle, astragalus root, ledebouriella root, pearl powder borneo camphor by certain weight ratio. it can be prepared into any of the conventional dosage forms for ophthalmology.

Description

[technical field] [0001] The invention relates to a medicine for treating chronic conjunctivitis and a preparation method thereof, belonging to the field of traditional Chinese medicines. [Background technique] [0002] Chronic conjunctivitis is a common disease in ophthalmology. In recent years, due to the popularization of computers and the aggravation of air pollution, the incidence of chronic conjunctivitis has increased year by year, and it has become the most common eye disease in ophthalmology. The patient feels that the eyes are dry, itchy, and visually fatigued, which seriously affects daily life and study and work. At present, there is no good effective drug in clinical practice. Commonly used antibiotics, vitamin eye drops and astringents are used for treatment, but the curative effect is not significant. Chinese patent disclosure Through some methods of using Chinese medicines to treat conjunctivitis, such as: CN1100953, CN1108556, CN1132627, CN1207322, CN8910575...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K36/35A61K36/238A61K35/56A61K31/045A61K9/00A61P1/00A61K35/618
Inventor 张海娟
Owner BEIJING INST OF OPHTHALMOLOGY
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