Ferromagnetic frame

By designing a strong magnetic stand with roof panel, jack, slide chute and magnetic plate structure, the problems of reagent tube fixation and magnetic force control in the prior art are solved, and the stable fixation of reagent tubes of different specifications and the improvement of magnetic bead adsorption effect of magnetic beads is achieved. , improves experimental efficiency and cost-effectiveness.

CN222119206UActive Publication Date: 2024-12-06INST OF SENSOR TECH GANSU ACAD OF SCI
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Patent Information

Application Number
CN202420727396.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-04-10
Publication Date
2024-12-06
Estimated Expiration
2034-04-10

AI Technical Summary

Technical Problem

The existing strong magnetic stand is difficult to effectively fix reagent tubes of different specifications, and the magnetic force control is poor, resulting in a faster settlement speed of magnetic beads or a weak adsorption effect, which affects experimental efficiency and cost.

Method used

A strong magnetic magnetic rack including a roof plate, jack, positioning hole, slide groove, telescopic rod and magnetic plate is designed. By manually operating the slide plate and telescopic rod, the spring and movable groove are used to achieve the fixation of the centrifuge tube and the position of the magnetic plate. Adjust, enhance magnetic force and adsorption effect.

Benefits of technology

It realizes stable fixation of reagent tubes of different specifications, avoids loosening of magnetic beads, improves experimental efficiency and cost-effectiveness, and facilitates the cleaning and purification of magnetic beads.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of biological experiment equipment, and provides a ferromagnetic magnetic frame which comprises a top plate, insertion holes and positioning holes, the insertion holes are formed in the outer wall of the top end of the top plate at equal intervals, a supporting plate is installed at the bottom end of the top plate, and a bottom plate is installed at the end, away from the top plate, of the supporting plate. Positioning holes are symmetrically formed in the outer wall of the top end of the bottom plate, sliding grooves are symmetrically formed in the outer walls of the two sides of the top plate, movable grooves are symmetrically formed in the inner wall of the top plate, the sliding grooves communicate with the movable grooves, side fixing blocks are movably installed on the top plate through the movable grooves, and sliding plates are symmetrically installed at the two ends of each side fixing block; one end of each sliding plate penetrates through the corresponding sliding groove and extends to the outer wall of the top plate, and telescopic rods are installed on the side walls of the sliding plates. By means of the technical scheme, the problems that in the prior art, a magnetic frame cannot stably clamp different centrifugal tubes, and the adsorption strength of a magnetic plate to magnetic beads is inconvenient to adjust are solved.
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Description

Technical Field

[0001] The utility model relates to the technical field of biological experimental equipment, in particular to a strong magnetic frame. Background Art

[0002] A strong magnetic stand is a device used in laboratories, medicine, and industry that uses strong magnetic forces to fix magnetic objects in a specific position. These magnetic stands are usually made of permanent magnetic materials, such as neodymium iron boron (NdFeB) magnets, which have strong magnetic properties. The technical background of strong magnetic stands involves magnetic materials, magnetic circuit design, structural design, safety, and application requirements. The application of these technologies helps to improve efficiency and precision in experiments, medicine, and industry.

[0003] However, in the implementation of related technologies, the existing strong magnetic racks have the following problems: There are some challenges in the current magnetic rack design. Due to the certain distance between the magnet and the magnetic beads at the bottom of the centrifuge tube, the magnetic force of the magnet on the magnetic beads is relatively small. Although the magnetic force can be enhanced by increasing the size of the magnetic beads, this will also bring new problems, such as accelerating the sedimentation rate of the magnetic beads, which is not conducive to the dispersion of the magnetic beads. On the other hand, if the magnetic force is too small, the adsorption effect of the magnetic beads will be affected. When using a pipette to absorb waste liquid, it is easy to absorb the magnetic beads as well, resulting in the magnetic beads being dumped out together with the supernatant during the separation process. In subsequent experiments, the magnetic beads need to be continuously replenished, and the experimental effect is poor and the cost is high. For this reason, we proposed a strong magnetic rack. Utility Model Content

[0004] The utility model provides a strong magnetic frame, which solves the problem in the related art that reagent tubes of different specifications cannot be fixed and the magnetic strength of the magnetic plate is difficult to control.

[0005] The technical solution of the utility model is as follows:

[0006] A strong magnetic frame comprises a top plate, a socket and a positioning hole, wherein the outer wall at the top of the top plate is provided with sockets at equal intervals, a support plate is installed at the bottom end of the top plate, a bottom plate is installed at the end of the support plate away from the top plate, positioning holes are symmetrically arranged on the outer wall at the top of the bottom plate, slide grooves are symmetrically arranged on the outer walls on both sides of the top plate, movable grooves are symmetrically arranged on the inner wall of the top plate, the slide grooves are communicated with the movable grooves, side fixing blocks are movably installed on the top plate through the movable grooves, slides are symmetrically installed on both ends of the side fixing blocks, one end of the slide groove extends through the slide groove to the outer wall of the top plate, telescopic rods are installed on the side walls of the slide, the end of the telescopic rod away from the slide is connected to one side of the slide groove, and a spring is installed on the outer wall of the telescopic rod.

[0007] Preferably, the slide plate is in a T-shaped structure, and the slide plate and the slide groove match each other.

[0008] Preferably, an arc-shaped notch is provided on a side of the side fixing block close to the centrifuge tube, and the arc-shaped notch matches the centrifuge tube.

[0009] Preferably, the outer wall of the support plate is provided with a movable hole, the inner wall of the movable hole is symmetrically and movably installed with a limit block, the outer wall of the limit block is connected through a telescopic sleeve, and the outer wall of the telescopic sleeve is installed with a magnetic plate.

[0010] Preferably, the movable hole is a circular through hole, and the inner diameter of the movable hole is the same as the outer diameter of the limiting block.

[0011] Preferably, the outer wall at the top end of the bottom plate is symmetrically and evenly spaced with positioning holes, and the positioning holes are groove structures.

[0012] Preferably, the cross section of the magnetic plate is in a broken line shape, and the magnetic plate is made of high-performance permanent magnetic material.

[0013] Preferably, a line connecting the center point of the insertion hole to the center point of the positioning hole is vertically upward, and the line coincides with the central axis of the centrifuge tube.

[0014] The working principle and beneficial effects of the utility model are:

[0015] 1. In the utility model, the top plate, the slide plate and the telescopic rod are provided, the slide plate is manually pulled, the telescopic rod and the spring are squeezed by the slide plate, the slide plate is limited by the slide groove, the side fixing block is laterally moved on the inner wall of the movable groove, the centrifuge tube is inserted through the jack, the bottom end of the centrifuge tube is fixed on the bottom plate through the positioning hole, the hand is released, the elastic force generated by the deformation of the spring is used to reset the slide plate and the movable groove, the notch provided on the side wall of the movable groove is used to press the side wall of one side of the centrifuge tube, so that the movable groove and the jack clamp the centrifuge tube. The structure is simple to operate and is convenient for fixing the centrifuge tube when pouring out waste liquid to prevent the centrifuge tube from loosening from the magnetic rack.

[0016] 2. In the utility model, by providing the magnetic plate, telescopic sleeve and limit block, when the centrifuge tube is fixed on the magnetic frame and one side of the centrifuge tube is close to the magnetic plate, the magnetic plate is pulled outward, the telescopic sleeve is stretched, and the limit block is partially moved to the outer wall of the movable hole, so that the magnetic plate fits the outer wall of one side of the centrifuge tube, and the magnetic plate wraps the outer wall of the centrifuge tube, thereby increasing the adsorption effect of the magnetic plate on the magnetic beads inside the centrifuge tube. This structure is convenient for purification experiments on the solution inside the centrifuge tube. When the magnetic beads need to be cleaned, the telescopic sleeve can be compressed to reset the magnetic plate to increase the distance between the magnetic plate and the centrifuge tube, thereby reducing the magnetic force and facilitating the elution of the magnetic beads inside the centrifuge tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] The utility model is further described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0018] Figure 1This is a schematic diagram of the main structure of the magnetic frame proposed by the utility model;

[0019] Figure 2 This is a schematic diagram of the half-section structure of the main body of the magnetic frame proposed in the utility model;

[0020] Figure 3 This is a schematic diagram of the movable slot structure proposed by the utility model;

[0021] Figure 4 This is a schematic diagram of the movable hole structure proposed by the utility model;

[0022] Figure 5 This is a schematic diagram of the magnetic plate structure proposed by the utility model.

[0023] In the figure: 1. top plate; 2. socket; 3. centrifuge tube; 4. slide groove; 5. slide plate; 6. support plate; 7. bottom plate; 8. positioning hole; 9. telescopic rod; 10. spring; 11. side fixing block; 12. movable groove; 13. magnetic plate; 14. movable hole; 15. telescopic sleeve; 16. limit block. DETAILED DESCRIPTION

[0024] The following will be combined with the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0025] Example 1: Figure 1 to Figure 5 As shown, the present embodiment proposes a strong magnetic frame, including a top plate 1, a socket 2 and a positioning hole 8. The outer wall at the top of the top plate 1 is provided with sockets 2 at equal intervals, a support plate 6 is installed at the bottom end of the top plate 1, a bottom plate 7 is installed at the end of the support plate 6 away from the top plate 1, and the outer wall at the top of the bottom plate 7 is symmetrically provided with positioning holes 8, the outer walls on both sides of the top plate 1 are symmetrically provided with slide grooves 4, the inner wall of the top plate 1 is symmetrically provided with movable grooves 12, the slide grooves 4 are communicated with the movable grooves 12, the top plate 1 is movably provided with side fixing blocks 11 through the movable grooves 12, and slide plates 5 are symmetrically installed at both ends of the side fixing blocks 11, one end of the slide plate 5 passes through the slide groove 4 and extends to the outer wall of the top plate 1, and the side walls of the slide plate 5 are all provided with telescopic rods 9, the end of the telescopic rod 9 away from the slide plate 5 is connected to one side of the slide groove 4, and the outer wall of the telescopic rod 9 is provided with a spring 10.

[0026] In this embodiment, the slide plate 5 is in a T-shaped structure, and the slide plate 5 and the slide groove 4 match each other.

[0027] In this embodiment, the outer wall at the top of the bottom plate 7 is symmetrically and evenly spaced with positioning holes 8, and the positioning holes 8 are groove structures.

[0028] In this embodiment, a line connecting the center point of the insertion hole 2 to the center point of the positioning hole 8 is vertically upward, and the line coincides with the center axis of the centrifuge tube 3 .

[0029] Specific as Figure 1 , Figure 2 and Figure 3 As shown, when using this structure, manually pull the slide plate 5, squeeze the telescopic rod 9 and the spring 10 through the slide plate 5, use the slide groove 4 to limit the slide plate 5, so that the side fixing block 11 moves laterally on the inner wall of the movable groove 12, insert the centrifuge tube 3 through the socket 2, and fix its bottom end on the bottom plate 7 through the positioning hole 8, release your hand, use the elastic force generated by the deformation of the spring 10 to reset the slide plate 5 and the movable groove 12, use the notch set in the side wall of the movable groove 12 to press the side wall of the centrifuge tube 3, so that the movable groove 12 and the socket 2 clamp the centrifuge tube 3. This structure is simple to operate and is convenient for fixing the centrifuge tube 3 when pouring out waste liquid to prevent the centrifuge tube 3 from loosening from the magnetic rack.

[0030] Embodiment 2: An arc-shaped notch is provided on one side of the side fixing block 11 close to the centrifuge tube 3 , and the arc-shaped notch matches the centrifuge tube 3 .

[0031] In this embodiment, the outer wall of the support plate 6 is provided with a movable hole 14, and the inner wall of the movable hole 14 is symmetrically and movably installed with a limit block 16. The outer wall of the limit block 16 is connected through a telescopic sleeve 15, and the outer wall of the telescopic sleeve 15 is installed with a magnetic plate 13.

[0032] In this embodiment, the movable hole 14 is a circular through hole, and the inner diameter of the movable hole 14 is the same as the outer diameter of the limiting block 16 .

[0033] In this embodiment, the cross section of the magnetic plate 13 is in a broken line shape, and the magnetic plate 13 is made of high-performance permanent magnetic material.

[0034] Specific as Figure 1 , Figure 4 and Figure 5 As shown, when this structure is used, when the centrifuge tube 3 is fixed on the magnetic frame and one side of the centrifuge tube 3 is close to the magnetic plate 13, the magnetic plate 13 is pulled outward, the telescopic sleeve 15 is stretched, and the limit block 16 is partially moved to the outer wall of the movable hole 14, so that the magnetic plate 13 fits the outer wall of one side of the centrifuge tube 3, and the magnetic plate 13 wraps the outer wall of the centrifuge tube 3, thereby increasing the adsorption effect of the magnetic plate 13 on the magnetic beads inside the centrifuge tube 3. This structure is convenient for purifying the solution inside the centrifuge tube 3. When the magnetic beads need to be cleaned, the telescopic sleeve 15 can be compressed to reset the magnetic plate 13 to increase the distance between it and the centrifuge tube 3, reduce the magnetic force, and facilitate the elution of the magnetic beads inside it.

[0035] Working principle: Manually pull the slide plate 5 at the same time, compress the telescopic rod 9 and the spring 10, use the slide groove 4 to limit the slide plate 5 so that the side fixing block 11 moves with the slide plate 5, so that the side fixing block 11 leaves the bottom of the socket 2, insert the centrifuge tube 3 from the socket 2, release the slide plate 5, use the elastic force generated by the deformation of the spring 10 to rebound so that the arc-shaped notch on one side of the movable groove 12 squeezes the inner wall of one side of the centrifuge tube 3, so that it cooperates with the inner wall of the socket 2 to clamp the centrifuge tube 3, and then use the positioning hole 8 to fix the bottom end of the centrifuge tube 3 to prevent it from shifting, and pull the magnetic plate 13 outward. , stretch the telescopic sleeve 15 to make the limit block 16 partially move out of the outer wall of the movable hole 14, reduce the distance between the magnetic plate 13 and the centrifuge tube 3, make the magnetic plate 13 fit the outer wall of the centrifuge tube 3, increase the adsorption area and magnetic force of the magnetic plate 13 on the magnetic beads inside the centrifuge tube 3, avoid the pipette sucking out the magnetic beads when sucking the waste liquid, and increase the experimental cost. When the magnetic beads need to be cleaned, after the waste liquid is emptied, the magnetic plate 13 is reset to reduce the adsorption of the magnetic beads and elute the magnetic beads. In addition, the structure can also be clamped and fixed for centrifuge tubes 3 of different diameters, which is convenient for experiments and reduces costs.

[0036] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A strong magnetic frame, comprising a top plate (1), a socket (2) and a positioning hole (8), It is characterized in that The outer wall of the top end of the top plate (1) is provided with insertion holes (2) at equal intervals, the bottom end of the top plate (1) is provided with a support plate (6), the end of the support plate (6) away from the top plate (1) is provided with a bottom plate (7), the outer wall of the top end of the bottom plate (7) is symmetrically provided with positioning holes (8), the outer walls of both sides of the top plate (1) are symmetrically provided with sliding grooves (4), the inner wall of the top plate (1) is symmetrically provided with movable grooves (12), the sliding grooves (4) and the movable grooves (12) are mutually connected. The top plate (1) is movably mounted with a side fixing block (11) through a movable groove (12), and slide plates (5) are symmetrically mounted at both ends of the side fixing block (11), one end of the slide plate (5) passes through the slide groove (4) and extends to the outer wall of the top plate (1), and telescopic rods (9) are mounted on the side walls of the slide plates (5), and one end of the telescopic rod (9) away from the slide plate (5) is connected to one side of the slide groove (4), and a spring (10) is mounted on the outer wall of the telescopic rod (9).

2. The strong magnetic frame according to claim 1, It is characterized in that The slide plate (5) is in a T-shaped structure, and the slide plate (5) and the slide groove (4) match each other.

3. The strong magnetic frame according to claim 1, It is characterized in that An arc-shaped notch is provided on one side of the side fixing block (11) close to the centrifuge tube (3), and the arc-shaped notch matches the centrifuge tube (3).

4. The strong magnetic frame according to claim 1, It is characterized in that The outer wall of the support plate (6) is provided with a movable hole (14), the inner wall of the movable hole (14) is symmetrically and movably mounted with a limit block (16), the outer wall of the limit block (16) is connected via a telescopic sleeve (15), and the outer wall of the telescopic sleeve (15) is mounted with a magnetic plate (13).

5. The strong magnetic frame according to claim 4, It is characterized in that The movable hole (14) is a circular through hole, and the inner diameter of the movable hole (14) is the same as the outer diameter of the limiting block (16).

6. The strong magnetic frame according to claim 1, It is characterized in that Positioning holes (8) are symmetrically and evenly spaced on the outer wall of the top end of the bottom plate (7), and the positioning holes (8) are groove structures.

7. The strong magnetic frame according to claim 4, It is characterized in that The cross section of the magnetic plate (13) is in the shape of a broken line, and the magnetic plate (13) is made of a high-performance permanent magnetic material.

8. The strong magnetic frame according to claim 1, It is characterized in that A line connecting the center point of the insertion hole (2) and the center point of the positioning hole (8) is vertically upward, and the line coincides with the center axis of the centrifuge tube (3).