Slice rack assembly
By designing the gradually rising slice support and limit stop structure, the problem of consistent immersion depth of the slides in the prior art is solved, and the timely fixation of tissue sheets is achieved on a single slide in batches, which improves the Fixed effect and stability.
Patent Information
- Application Number
- CN202420937286.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-02-23
- Publication Date
- 2025-01-03
- Estimated Expiration
- 2034-02-23
AI Technical Summary
The existing intraoperative frozen pathological section racks are difficult to meet the timely fixation of the tissue sheets in batches on a slide, and the consistency of the depth of the frame immersed in the fixing liquid in the prior art leads to poor fixation effect of the tissue sheets.
A slice support member that includes a gradually rising along the length direction is designed to form multiple slice support steps for supporting the slide, and to stabilize the slide position through the limit stop and slot structure to ensure that the slide is in The immersion depth can be adjusted when pasting different tissue sheets to meet the batch fixation of tissue sheets.
Timely fixation of multiple tissue sheets on a slide is achieved in batches, avoiding the problem of wetting on the top of the slide, improving the fixation effect of the tissue sheets, and reducing the risk of shaking of the slides.
Smart Images

Figure CN222299299U_ABST
Abstract
Description
Technical Field
[0001] The utility model is a divisional application with an application date of February 23, 2024, an application number of 2024203338428, and a utility model name of a frozen pathological slice rack during surgery. The utility model relates to the field of medical and health technology, and in particular to a slice rack assembly. Background Art
[0002] During intraoperative frozen pathology diagnosis of diseases, continuous or deep tissue cutting is often required, especially for cutting edges and lymph node tissues, which often require deep cutting. A large number of tissue slices will be produced. In order to reduce the number of slides to reduce medical costs and storage burdens, two or more tissue slices are often pasted on a slide. In order to ensure the fixation effect of fresh tissue slices, it is necessary to put the separated tissue slices into a fixing frame inserted into the fixing liquid as soon as possible to achieve the fixation of the tissue slices. Generally, it is necessary to temporarily place the slide with a tissue slice pasted on it, and then take out the slide after the second tissue slice is separated and paste the second tissue slice on the slide, so that two tissue slices are pasted on the same slide.
[0003] In order to facilitate the fixation of tissue slices, in the related art, the patent with publication number CN202511991U discloses a movable pathological slice rack. It forms a plurality of spaced slice slots for slices to be inserted, which can temporarily store the slides and reduce the space occupied by the slide storage. When in use, the rack body is immersed in the fixative to fix the tissue slices on multiple slides at the same time.
[0004] However, the use of this frame will cause each slide to be immersed in the fixative to the same depth, so that the slide with one tissue slice attached to it and the slide with multiple tissue slices attached to it will be immersed in the same depth of the fixative. If the frame is immersed in the fixative too deeply, the slide with one tissue slice attached to it will be immersed in the fixative too deeply and the surface will be wet, making it difficult to continue to attach other tissue slices. If the frame is immersed in the fixative too shallowly, the slide with multiple tissue slices attached to it will be immersed in the fixative too shallowly and the tissue slices cannot be fixed well. In other words, the existing slice holder is difficult to meet the needs of timely fixation of tissue slices attached in batches on a slide. Utility Model Content
[0005] The utility model provides an intraoperative frozen pathology slice rack, which is used for timely fixing glass slides for pasting tissue slices in batches.
[0006] In a first aspect, the utility model provides an intraoperative frozen pathology slice rack, comprising: a rack body; a slice support member, the slice support member is installed on the rack body, and the top surface of the slice support member gradually rises along its length direction to form a plurality of slice support steps, and the slice support steps are used to support a glass slide.
[0007] In one embodiment, the lengths of the slice support steps in the length direction of the slice support are equal.
[0008] In one embodiment, the height difference between any two adjacent slice supporting steps is equal.
[0009] In one embodiment, it also includes a plurality of first limit stops, which are arranged at intervals along the length direction of the slice support, and the first limit stops are all connected to the frame. The plurality of first limit stops spaced apart from each other form a plurality of first slots spaced apart from each other on the side of the slice support, and the first slots are used for inserting the slide.
[0010] In one embodiment, the first limit stops extend vertically, and the first limit stops are parallel to each other.
[0011] In one embodiment, a second support member is also installed on the frame, and the second support member is symmetrical with the slice support member along a first symmetry axis. The first symmetry axis is horizontally arranged and the extension direction is in the same direction as the length direction of the slice support member. A plurality of second limit stops are installed on the second support member, and each second limit stop corresponds to a first limit stop symmetrical along the first symmetry axis. The spacing between the slice support member and the second support member is smaller than the width of the slide.
[0012] In one embodiment, the frame includes a first vertical beam and a second vertical beam, the first vertical beam is arranged in parallel with the second vertical beam, one end of the slice support is connected to the first vertical beam, and the other end of the slice support is connected to the second vertical beam. The frame also includes a first cross beam, the first cross beam connects the first vertical beam and the second vertical beam, and the first cross beam is connected to the slice support.
[0013] In one embodiment, the slice support, the first vertical beam and the first horizontal beam form a triangular structure.
[0014] In one embodiment, the frame further includes a second crossbeam, on which a plurality of spaced third stoppers are mounted to form a plurality of second slots of equal height, wherein the second slots are used for inserting glass slides.
[0015] In one embodiment, a handle is also installed on the frame.
[0016] In the second aspect, the utility model also provides a slice rack assembly for supporting a pathology slice rack with a glass slide, which includes: a connecting piece, which is used to be detachably connected to the pathology slice rack; a slice support piece, which is connected to the connecting piece, and the top surface of the slice support piece gradually rises along its length direction to form a plurality of slice support steps, and the slice support steps are used to support the glass slide.
[0017] In one embodiment, the connecting member extends out of the slice support member at both ends in the width direction, and the width of the connecting member is equal to the width of the slide, the thickness of the connecting member is equal to the thickness of the slide, and the connecting member is used to be inserted into the slice slot of the pathology slice rack.
[0018] In one embodiment, a reinforcing member is further included, which is connected to a side of the connecting member where a slice support member is provided. The slice support member is supported on the top surface of the reinforcing member, and the reinforcing member is bent to form a bottom plate portion and an inclined plate portion. One end of the bottom plate portion and the inclined plate portion away from the bending area are both connected to the connecting member, and the reinforcing member and the connecting member form a triangular structure.
[0019] In one embodiment, the reinforcement member is integrally formed with the slice support member.
[0020] In one embodiment, the lengths of the slice support steps in the length direction of the slice support are equal.
[0021] In one embodiment, the height difference between any two adjacent slice supporting steps is equal.
[0022] Compared with the prior art, the utility model has the advantage that the support of the glass slide is realized by using a slice support member that gradually rises along the length direction. When a piece of tissue slice is pasted on the glass slide, the glass slide can be placed on a slice support step at a high position, so as to prevent the top of the glass slide from being immersed in the fixative while satisfying the fixation of the tissue slice at the bottom of the glass slide, which facilitates the subsequent pasting of tissue slices on the glass slide. When two or more tissue slices are pasted on the glass slide, it can be placed on a slice support step at a low position, so that the glass slide is more immersed in the fixative to satisfy the fixation of the tissue slice. Therefore, the present application can satisfy the paste of multiple tissue slices in batches on a glass slide, and can ensure the timely fixation of the tissue slices.
[0023] Moreover, since the slice rack assembly does not include a frame structure, but can be detachably mounted on an existing slice rack, the slice rack assembly can be directly mounted on a slice rack that is matched with the freezing automatic staining machine itself, and has a wider scope of application.
[0024] Since the slice rack assembly provided by the utility model can be directly used on the existing pathology slice rack, it is also applicable to the automatic staining machine integrated with the pathology slice rack. In contrast, when the intraoperative frozen pathology slice rack needs to be stained with the automatic staining machine, the slides on the intraoperative frozen pathology slice rack need to be transferred to the pathology slice rack matched with the automatic staining machine itself, and the staining process is relatively cumbersome.
[0025] The slice rack assembly provided by the utility model is more convenient and quick when staining, and the slice rack assembly can be installed on the pathology slice rack matched with the automatic staining machine first. When fixing tissue slices, the slice rack assembly installed in the pathology slice rack matched with the automatic staining machine can be used to achieve batch pasting and timely fixation of tissue slices on a single glass slide. After the tissue slices on each glass slide are fixed, each glass slide has been adjusted to a lower position, and the pathology slice rack matched with the automatic staining machine can be directly placed in the automatic staining machine for staining. Compared with the intraoperative frozen pathology slice rack with a frame structure, the step of replacing the frame is omitted, reducing the risk of mistakes. BRIEF DESCRIPTION OF THE DRAWINGS
[0026] The present invention will be described in more detail below based on embodiments and with reference to the accompanying drawings.
[0027] Figure 1 It is a schematic diagram of the main cross-sectional structure of the intraoperative frozen pathological section rack in the embodiment of the utility model;
[0028] Figure 2 It is a schematic diagram of a top view of the cross-sectional structure of a frozen pathological section rack during surgery in an embodiment of the utility model;
[0029] Figure 3 It is a left-side cross-sectional structural schematic diagram of an intraoperative frozen pathological section rack in an embodiment of the utility model;
[0030] Figure 4 It is a schematic diagram of the main structure of the slice rack assembly in the embodiment of the utility model;
[0031] Figure 5 It is a three-dimensional structural schematic diagram of a slice rack assembly in an embodiment of the utility model;
[0032] Figure 6 It is a schematic diagram of the top view of the slice rack assembly in the embodiment of the utility model;
[0033] Figure 7 It is a right side structural schematic diagram of the slice rack assembly in the embodiment of the utility model.
[0034] Reference numerals:
[0035] 1. frame; 11. first vertical beam; 12. second vertical beam; 13. first horizontal beam; 14. second horizontal beam; 15. handle; 2. slice support; 21. slice support step; 3. first limit stop; 4. first slot; 5. second support; 6. second limit stop; 7. third stop;
[0036] 8. Connecting member; 9. Reinforcing member; 91. Bottom plate portion; 92. Inclined plate portion. DETAILED DESCRIPTION
[0037] The utility model will be further described below in conjunction with the accompanying drawings.
[0038] like Figure 1 As shown, an intraoperative frozen pathology section rack provided in an embodiment of the present application includes: a rack body 1 and a section support 2.
[0039] The slice support 2 is mounted on the frame 1, and the top surface of the slice support 2 is along its length direction (i.e. Figure 1 The slice supporting steps 21 are gradually raised in the left-right direction shown in the figure to form a plurality of slice supporting steps 21, and the slice supporting steps 21 are used to support the slide glass.
[0040] When using the intraoperative frozen pathology section rack provided by the present application, the rack body 1 can be placed in a container containing a fixative. When the first tissue slice is attached to the slide, the attached slide can be placed on the high section support step 21, so that the top of the slide is kept dry while the tissue slice at the bottom of the slide is soaked in the fixative.
[0041] When the slide needs to be attached to a second tissue slice, the slide can be taken out from the slice support step 21. Since the top area of the slide is dry, the subsequent tissue slice can be attached normally, avoiding the situation that the upper part of the slide is wet and cannot meet the requirements of the attachment of the subsequent tissue slice. After the second tissue slice is attached, the slide can be placed on the lower slice support step 21, so that the slide is more immersed in the tissue fluid, which meets the requirements of fixing the upper tissue slice.
[0042] That is to say, the intraoperative frozen pathology slice holder provided in the present application can meet the requirements of pasting multiple tissue slices in batches on a glass slide, and can ensure the timely fixation of the tissue slices.
[0043] like Figure 1 As shown, in some embodiments, the lengths of the slice supporting steps 21 in the length direction of the slice supporting member 2 are equal, so as to avoid the situation that some slice supporting steps 21 are too narrow to meet the requirements for installing the slide.
[0044] like Figure 2 As shown, in some implementations, the height difference between any two adjacent slice support steps 21 is equal. The height difference between two slides supported on adjacent slice support steps 21 is constant, which is convenient for evaluating the position where the slide should be inserted according to the pasting height of the tissue slice.
[0045] like Figure 1 and Figure 2As shown, in some implementations, the frozen pathology section rack further includes a plurality of first limit stops 3, which are arranged at intervals along the length direction of the section support 2, and the first limit stops 3 are all connected to the rack body 1, and the plurality of first limit stops 3 spaced apart from each other form a plurality of first slots 4 spaced apart from each other on the side of the section support 2, and the first slots 4 are used for inserting glass slides.
[0046] That is to say, the first slot 4 formed by the first limit stopper 3 prevents the glass slide from shaking back and forth, thereby improving the stability of the glass slide when it is fixed.
[0047] In other implementations, a slot structure may be provided on the slice supporting step 21 to prevent the glass slide from shaking.
[0048] In the present application, each slice supporting step 21 corresponds to a first slot 4, that is, the heights of the slides inserted into different first slots 4 are different.
[0049] like Figure 1 As shown, in some embodiments, the first limit stopper 3 extends vertically, and the first limit stoppers 3 are parallel to each other. The vertically extending first limit stopper 3 can form a vertical first slot 4, and the extraction process only requires lifting the slide upward, which is more convenient than extracting the slide in an inclined direction.
[0050] like Figure 1 , Figure 2 as well as Figure 3 As shown, in some embodiments, a second support member 5 is also installed on the frame 1, and the second support member 5 is symmetrical with the slice support member 2 along the first symmetry axis. The first symmetry axis is horizontally arranged and the extension direction is in the same direction as the length direction of the slice support member 2. A plurality of second limit stops 6 are installed on the second support member 5, and each second limit stop 6 corresponds to a first limit stop 3 symmetrical along the first symmetry axis, and the spacing between the slice support member 2 and the second support member 5 is smaller than the width of the slide.
[0051] After the glass slide is inserted into the first slot 4, the glass slide can be supported on the top of the slice support 2 and the second support 5 at the same time. Since the slice support 2 and the second support 5 are symmetrical along the first symmetry axis, the heights of both sides of the glass slide are the same, thereby reducing the risk of the glass slide shaking.
[0052] like Figure 2 As shown, the slice support 2 and the second support 5 are spaced apart. When the slide glass is supported on the slice support 2, its bottom part is suspended to facilitate the contact between the fixing liquid or the staining liquid and the slide glass.
[0053] like Figure 1As shown, in some embodiments, the frame 1 includes a first vertical beam 11 and a second vertical beam 12, the first vertical beam 11 and the second vertical beam 12 are arranged in parallel, one end of the slice support 2 is connected to the first vertical beam 11, and the other end of the slice support 2 is connected to the second vertical beam 12, the frame 1 also includes a first cross beam 13, the first cross beam 13 connects the first vertical beam 11 and the second vertical beam 12, and the first cross beam 13 is connected to the slice support 2.
[0054] The first cross beam 13 can maintain the relative position between the first vertical beam 11 and the second vertical beam 12, thereby preventing the slicing support 2 from being misplaced due to the offset of the first vertical beam 11 relative to the second vertical beam 12, thereby reducing the risk of misplacement of the slicing support 2.
[0055] like Figure 1 As shown, the slice support 2, the first vertical beam 11 and the first horizontal beam 13 are surrounded to form a triangular structure. The triangular structure can improve the stability of the frame 1.
[0056] like Figure 1 As shown, in some embodiments, the frame 1 further includes a second crossbeam 14, on which a plurality of spaced third stoppers 7 are mounted to form a plurality of second slots of equal height, and the second slots are used for inserting glass slides. When in use, the glass slides with two or more tissue slices attached thereto can be inserted into the second slots for continued fixation, or the entire frame can be placed in a dye solution for dyeing.
[0057] like Figure 1 As shown, in some embodiments, a handle 15 is also installed on the frame 1, which can be used by operators to carry the entire frame 1. In the present application, the handle 15 is arranged in the central area of the frame 1.
[0058] like Figure 4 and Figure 5 As shown, the utility model also provides a slice rack assembly for a pathology slice rack, which includes: a connecting member 8 and a slice support member 2. When a new intraoperative frozen pathology slice rack is not purchased, the function similar to that of the intraoperative frozen pathology slice rack can be achieved by installing it on various types of current vertical pathology slice racks.
[0059] Specifically, the connecting member 8 is used to be detachably connected to the pathology slice rack, the slice support 2 is connected to the connecting member 8, and the top surface of the slice support 2 gradually rises along its length direction to form a plurality of slice support steps 21, and the slice support steps 21 are used to support the slide.
[0060] That is to say, by installing the connecting member 8 on the pathological slice rack, the conventional pathological slice rack can have slice supporting steps 21 of various heights.
[0061] When in use, when the first tissue slice is pasted on the slide, the pasted slide can be placed on the high slice support step 21, so that the top of the slide can be kept dry while the tissue slice at the bottom of the slide is immersed in the fixative.
[0062] When the slide needs to be attached to a second tissue slice, the slide can be taken out from the slice support step 21. Since the top area of the slide is dry, the subsequent tissue slice can be attached normally, avoiding the situation that the upper part of the slide is wet and cannot meet the requirements of the attachment of the subsequent tissue slice. After the second tissue slice is attached, the slide can be placed on the lower slice support step 21, so that the slide is more immersed in the tissue fluid, which meets the requirements of fixing the upper tissue slice.
[0063] That is to say, after the traditional pathology slice rack is installed with the slice rack assembly, it can meet the needs of pasting multiple tissue slices in batches on a glass slide and ensure that the tissue slices are fixed in time.
[0064] Compared with replacing the traditional pathology slice rack with an intraoperative frozen pathology slice rack, since it does not have a frame structure, its material cost is lower than that of an intraoperative frozen pathology slice rack with a frame structure. In other words, the modification cost of the slice rack assembly provided by the utility model is lower.
[0065] Moreover, the slice rack assembly can be adapted to the pathological slice rack integrated in the staining machine, and after the tissue slice is fixed, it can be directly stained by the staining machine. In contrast, the intraoperative frozen pathological slice rack with a frame structure needs to transfer the slide to the pathological slice rack of the staining machine itself during the staining process. The slice rack assembly provided by the utility model is easier to operate during the staining process.
[0066] like Figure 4 as well as Figure 6 As shown, the lengths of the slice support steps 21 in the length direction of the slice support 2 are equal, so as to avoid the situation that some slice support steps 21 are too narrow to meet the installation requirements of the slide.
[0067] like Figure 4 as well as Figure 7 As shown, the height difference between any two adjacent slice support steps 21 is equal. The height difference between two slides supported on adjacent slice support steps 21 is constant, which is convenient for evaluating the position where the slide should be inserted according to the pasting height of the tissue slice.
[0068] In the present application, the connecting member 8 is directly inserted into the slice slot of the pathology slice rack. Since the length and width of the connecting member 8 are respectively equal to the length and width of the slide, it can be directly adapted to all current vertical pathology slice racks. In other embodiments, the connecting member 8 can also be provided with other connection modes such as clamping and bonding with the pathology slice rack.
[0069] like Figure 5 as well as Figure 6 As shown, in some implementations, the connecting member 8 is Figure 6 Both ends of the connecting member 8 (in the left and right directions) extend out of the slice support 2, and the width of the connecting member 8 is equal to the width of the slide, the thickness of the connecting member 8 is equal to the thickness of the slide, and the connecting member 8 is used to be inserted into the slice slot of the pathology slice rack (the structure is similar to the first slot 4 formed by the adjacent first limit stopper 3).
[0070] In the related art, the pathology slice rack is provided with baffles arranged at intervals along the length direction (such as the baffles in patent CN202511991U), and two adjacent baffles form a slice slot for inserting a glass slide (such as the slot in patent CN202511991U). In the present application, by extending the connecting member 8 out of the slice support member 2 in the width direction, that is, the width of the slice support member 2 is smaller than the width of the connecting member 8, the end of the connecting member 8 in the width direction can be inserted into the slice slot, so that the connecting member 8 is installed on the pathology slice rack.
[0071] When installing the slide, the slide rack assembly can be first inserted into the slot of the pathology slide rack, and then the slide can be supported on the slide support step 21 on the slide rack assembly according to the number of tissue slices and the depth of the fixative. In another implementation, the slide can be stabilized by providing a structure such as a card slot on the slide support step 21 to prevent the slide from shaking.
[0072] The slice supports 2 of different widths may be designed according to the form of the pathological slice rack to avoid the connection member 8 being unable to be inserted into the slice slot due to interference of the slice support 2 .
[0073] like Figure 4 as well as Figure 5 As shown, in some embodiments, the slice rack assembly also includes a reinforcement member 9, which is connected to one side of the connecting member 8 where the slice support member 2 is provided, and the slice support member 2 is supported on the top surface of the reinforcement member 9, and the reinforcement member 9 is bent to form a bottom plate portion 91 and an inclined plate portion 92, and the ends of the bottom plate portion 91 and the inclined plate portion 92 away from the bending area are both connected to the connecting member 8, and the reinforcement member 9 and the connecting member 8 form a triangular structure.
[0074] Specifically, the inclined plate portion 92 is located above the bottom plate portion 91, and the bottom surface of the slice support 2 is in contact with the top inclined surface of the inclined plate portion 92. The strength of the slice rack assembly is improved by the triangular structure formed by the reinforcing member 9 and the connecting member 8, wherein preferably, the reinforcing member 9 adopts a plate-like structure, and the left and right sides of the triangular structure are connected to the outside world, and when the slice rack assembly is inserted into the pathology slice rack, the fixative can flow into the enclosed triangular space. The reinforcing member 9 provided in the present application has little effect on the liquid level of the fixative, and the liquid level of the fixative will not rise sharply.
[0075] In this embodiment, the reinforcing member 9 and the slice supporting member 2 can be formed in one piece, or they can be produced separately and then assembled and connected.
[0076] Although the present invention has been described with reference to preferred embodiments, various modifications may be made thereto and parts thereof may be replaced with equivalents without departing from the scope of the present invention. In particular, the various technical features mentioned in the various embodiments may be combined in any manner as long as there is no structural conflict. The present invention is not limited to the specific embodiments disclosed herein, but includes all technical solutions falling within the scope of the claims.
Claims
1. A slide holder assembly, used to be detachably connected to a pathology slide holder to support a slide, characterized in that: It includes: A connecting piece, the connecting piece is used to be detachably connected to the pathology slice rack; A slice support member is connected to the connecting member, and the top surface of the slice support member gradually rises along its length direction to form a plurality of slice support steps, and the slice support steps are used to support the slide.
2. The slicer frame assembly according to claim 1, characterized in that: The connecting member extends out of the slice supporting member at both ends in the width direction thereof, and the width of the connecting member is equal to the width of the glass slide, the thickness of the connecting member is equal to the thickness of the glass slide, and the connecting member is used to be inserted into the slice slot of the pathology slice rack.
3. The slicer frame assembly according to claim 1, characterized in that: The slice frame assembly further comprises a reinforcing member, wherein the reinforcing member is connected to one side of the connecting member where the slice supporting member is provided, and the slice supporting member is supported on the top surface of the reinforcing member.
4. The slicer frame assembly according to claim 3, characterized in that: The reinforcing member is bent to form a bottom plate portion and an inclined plate portion, and one end of the bottom plate portion and the inclined plate portion away from the bending area are both connected to the connecting member, and the reinforcing member and the connecting member form a triangular structure.
5. The slicer frame assembly according to claim 3, characterized in that: The reinforcing member is integrally formed with the slice supporting member.
6. The slicer frame assembly according to claim 1, characterized in that: The lengths of the slice supporting steps in the length direction of the slice supporting member are equal.
7. The slicer frame assembly according to claim 1, characterized in that: The height difference between any two adjacent slice support steps is equal.
8. The slicer frame assembly according to claim 1, characterized in that: The connecting piece is detachably plugged into the slice slot of the pathology slice rack; Alternatively, the connecting piece is detachably connected to the pathology slice rack by snapping and / or bonding.
9. The slicer frame assembly according to claim 1, characterized in that: A slot structure is provided on the slice supporting step to stabilize the slide.