Pectin hemostatic gauze and preparation method thereof

Abstract

The invention discloses a pectin hemostatic gauze which is characterized by being prepared from the following raw materials in parts by weight: 8-12 parts of pectin, 4-6 parts of gelatin, 1-2 parts of poloxamer 188, 3-5 parts of sodium alga acid, 1-2 parts of wheat germ oil, 1-2 parts of soybean oil, 0.1-0.2 part of polysorbate-80, 0.05-0.1 part of propylgallate, 1-2 parts of lactose, 1-2 parts of xylitol, 2-4 parts of sodium carboxymethylcellulose, 1-2 parts of auxiliary materials and 200-250 parts of water. A soluble hemostatic gauze is prepared by taking natural pectin as a main ingredient, has a good hemostatic function and can achieve the effects of resisting bacteria, diminishing inflammation and protecting the wound; and meanwhile, the pectin hemostatic gauze is rich in raw materials, simple in preparation process, low in cost, safe, environment-friendly and high in biocompatibility, is easily absorbed by a human body and does not have any toxic or side effect.

Description

technical field

[0001] The invention relates to the field of medicine, in particular to a pectin hemostatic gauze and a preparation method thereof. Background technique

[0002] With the continuous advancement of medical technology, new medical materials and related technologies have been well developed. Among them, the development and improvement of hemostatic materials are conducive to improving the problems of surgical bleeding and bleeding, which is of great significance and has become a hot research topic in the field of medicine. Traditional hemostatic gauze is generally made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affect wound healing, and are easy to adhere to wound tissue during use, causing secondary damage. The generated waste has a complicated treatment process and is easy to pollute the environment.

[0003] Soluble hemostatic gauze is a new type of hemostatic mat...

Examples

Embodiment Construction

[0020] Non-limiting examples of the present invention are as follows:

[0021] A kind of pectin hemostatic gauze is prepared from the component raw materials of following weight (kg):

[0022] Pectin 10, Gelatin 5, Poloxamer 188 1.5, Sodium Alginate 4, Wheat Germ Oil 1.5, Soybean Oil 1.5, Polysorbate-80 0.15, Propyl Gallate 0.08, Lactose 1.5, Xylitol 1.5, Carboxylic Sodium methylcellulose 3, excipients 1.5, water 200;

[0023] Among them, the auxiliary materials are made of raw materials with the following weights (kg):

[0024] Soy lecithin 0.8, glycerin 3, polyethylene glycol 1.5, bletilla striata superfine powder 1.5, mannitol 3, chlorhexidine gluconate 1.5, vitamin C 1.5, water 18;

[0025] Preparation method of excipients:

[0026] Add soybean lecithin into water at 60°C and stir at 1000r / min for 1 hour, then add glycerin, polyethylene glycol, superfine powder of Bletilla striata and mannitol and stir for 15 minutes under the same conditions, after cooling, add the res...

technical field

[0001] The invention relates to the field of medicine, in particular to a pectin hemostatic gauze and a preparation method thereof. Background technique

[0002] With the continuous advancement of medical technology, new medical materials and related technologies have been well developed. Among them, the development and improvement of hemostatic materials are conducive to improving the problems of surgical bleeding and bleeding, which is of great significance and has become a hot research topic in the field of medicine. Traditional hemostatic gauze is generally made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affect wound healing, and are easy to adhere to wound tissue during use, causing secondary damage. The generated waste has a complicated treatment process and is easy to pollute the environment.

[0003] Soluble hemostatic gauze is a new type of hemostatic mat...

Examples

Embodiment Construction

[0020] Non-limiting examples of the present invention are as follows:

[0021] A kind of pectin hemostatic gauze is prepared from the component raw materials of following weight (kg):

[0022] Pectin 10, Gelatin 5, Poloxamer 188 1.5, Sodium Alginate 4, Wheat Germ Oil 1.5, Soybean Oil 1.5, Polysorbate-80 0.15, Propyl Gallate 0.08, Lactose 1.5, Xylitol 1.5, Carboxylic Sodium methylcellulose 3, excipients 1.5, water 200;

[0023] Among them, the auxiliary materials are made of raw materials with the following weights (kg):

[0024] Soy lecithin 0.8, glycerin 3, polyethylene glycol 1.5, bletilla striata superfine powder 1.5, mannitol 3, chlorhexidine gluconate 1.5, vitamin C 1.5, water 18;

[0025] Preparation method of excipients:

[0026] Add soybean lecithin into water at 60°C and stir at 1000r / min for 1 hour, then add glycerin, polyethylene glycol, superfine powder of Bletilla striata and mannitol and stir for 15 minutes under the same conditions, after cooling, add the res...