Traditional Chinese medicine gel for promoting wound healing in lateral perineotomy

Abstract

The invention belongs to the field of traditional Chinese medicine and discloses traditional Chinese medicine gel for promoting wound healing in lateral perineotomy. The traditional Chinese medicine gel is prepared from, by weight, 10%-20% of traditional Chinese medicine extractive, 0.5%-4.5% of carbomer 940, 0.5%-3.5% of polyvinylpyrolidone K30, 3%-10% of glycerinum, 0.5%-1.3% of polysorbate, 0%-10% of triethanolamine, 0.3%-0.5% of ethylparaben, 0.5%-5% of azone and the balance water. The traditional Chinese medicine extractive is prepared from longpeduncle kadsura roots, folium ilicis chinensis, Indian lalimeris herb, stahlianthus involucratus and adina pilulifera leaves. The gel can promote the blood circulation at a wound part, seepage and absorption of medicine in local tissue is promoted from the outside to the inside, and the purposes of dredging the channel, promoting blood circulation to remove blood stasis, relieving pain and promoting wound healing are achieved; the gel is uniform and fine in texture, is easy to smear after being spread, the pH value of the gel is closer to the skin environment, neither a puerpera nor lactation of a baby can be influenced, the compliance of the patient for accepting treatment is greatly improved, and the living quality of puepera and the baby are improved.

Description

technical field

[0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine gel for promoting episiotomy wound healing. Background technique

[0002] Episiotomy is a common operation in obstetric delivery. The purpose of lateral episiotomy is to shorten the second stage of labor to avoid fetal delivery obstruction, fetal distress, prolonged labor and soft tissue damage caused by the prolongation of the second stage of labor to ensure the safety of mother and child. In recent years, during childbirth, the number of primiparas has been increasing and the fetal weight is on the rise. In order to avoid complications and reduce unnecessary injuries to mothers and babies, the number of episiotomy and sutures has increased significantly. Vaginal surgical procedures can lead to episiotomy wound infection. After infection of the episiotomy wound, local induration, pain, and suppuration may occur, affecting t...

Examples

Embodiment 1

[0068] Composition of traditional Chinese medicine extracts: 12 parts of Hongmuxiang, 30 parts of Sijiqingye, 26 parts of Malan, 20 parts of Tutianqi, and 22 parts of Shuituanhuaye.

[0069] Gel formula: Chinese medicine extract 12%, carbomer 9402.5%, polyvinylpyrrolidone k301.6%, glycerin 5.5%, polysorbate 0.8%, triethanolamine 2.0%, ethylparaben 0.35%, azone 1.5 %, the balance is water;

[0070] Preparation method: Add 8-10 times the amount of water to the ultrafinely pulverized mahogany and Tutianqi, soak for 2-5 hours, and extract the total volatile oil by steam distillation; weigh lecithin, cholesterol (lecithin and cholesterol) The mass ratio is 5.5:1), put it in a round bottom flask, add ether to dissolve it, evaporate the ether under reduced pressure at 55°C, add an appropriate amount of distilled water (so that the concentration of phospholipids is 6.5mg / ml), and incubate at 55°C 20-30min, homogenize with a high-speed dispersing homogenizer, add mahogany and seven to...

Embodiment 2

[0074] Composition of traditional Chinese medicine extracts: 12 parts of Hongmuxiang, 30 parts of Sijiqingye, 26 parts of Malan, 20 parts of Tutianqi, and 22 parts of Shuituanhuaye.

[0075] Gel formula: Chinese medicine extract 15%, carbomer 9402.8%, polyvinylpyrrolidone k301.8%, glycerin 6.5%, polysorbate 0.9%, triethanolamine 3.0%, ethylparaben 0.4%, azone 1.5 %, the balance is water;

[0076] Preparation method: Add 8-10 times the amount of water to the ultrafinely pulverized mahogany and Tutianqi, soak for 2-5 hours, and extract the total volatile oil by steam distillation; weigh lecithin, cholesterol (lecithin and cholesterol) The mass ratio is 6.5:1), put it in a round bottom flask, add ether to dissolve it, evaporate the ether under reduced pressure at 50°C, add an appropriate amount of distilled water (so that the concentration of phospholipids is 5.5mg / ml), and incubate at 55°C 20-30min, homogenize with a high-speed dispersing homogenizer, add mahogany and seven tot...

Embodiment 3

[0080] Composition of traditional Chinese medicine extracts: 12 parts of Hongmuxiang, 30 parts of Sijiqingye, 26 parts of Malan, 20 parts of Tutianqi, and 22 parts of Shuituanhuaye.

[0081] Gel formula: Chinese medicine extract 17%, carbomer 9403.5%, polyvinylpyrrolidone k301.5%, glycerin 6.5%, polysorbate 1.1%, triethanolamine 3.4%, ethylparaben 0.35%, azone 2.5 %, the balance is water;

[0082] Preparation method: Add 8-10 times the amount of water to the ultrafinely pulverized mahogany and Tutianqi, soak for 2-5 hours, and extract the total volatile oil by steam distillation; weigh lecithin, cholesterol (lecithin and cholesterol) The mass ratio is 7:1), put it in a round bottom flask, add ether to dissolve it, evaporate the ether under reduced pressure at 60°C, add an appropriate amount of distilled water (so that the concentration of phospholipids is 7.0mg / ml), and incubate at 58°C 20-30min, homogenize with a high-speed dispersing homogenizer, add mahogany and seven tota...

technical field

[0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine gel for promoting episiotomy wound healing. Background technique

[0002] Episiotomy is a common operation in obstetric delivery. The purpose of lateral episiotomy is to shorten the second stage of labor to avoid fetal delivery obstruction, fetal distress, prolonged labor and soft tissue damage caused by the prolongation of the second stage of labor to ensure the safety of mother and child. In recent years, during childbirth, the number of primiparas has been increasing and the fetal weight is on the rise. In order to avoid complications and reduce unnecessary injuries to mothers and babies, the number of episiotomy and sutures has increased significantly. Vaginal surgical procedures can lead to episiotomy wound infection. After infection of the episiotomy wound, local induration, pain, and suppuration may occur, affecting t...

Examples

Embodiment 1

[0068] Composition of traditional Chinese medicine extracts: 12 parts of Hongmuxiang, 30 parts of Sijiqingye, 26 parts of Malan, 20 parts of Tutianqi, and 22 parts of Shuituanhuaye.

[0069] Gel formula: Chinese medicine extract 12%, carbomer 9402.5%, polyvinylpyrrolidone k301.6%, glycerin 5.5%, polysorbate 0.8%, triethanolamine 2.0%, ethylparaben 0.35%, azone 1.5 %, the balance is water;

[0070] Preparation method: Add 8-10 times the amount of water to the ultrafinely pulverized mahogany and Tutianqi, soak for 2-5 hours, and extract the total volatile oil by steam distillation; weigh lecithin, cholesterol (lecithin and cholesterol) The mass ratio is 5.5:1), put it in a round bottom flask, add ether to dissolve it, evaporate the ether under reduced pressure at 55°C, add an appropriate amount of distilled water (so that the concentration of phospholipids is 6.5mg / ml), and incubate at 55°C 20-30min, homogenize with a high-speed dispersing homogenizer, add mahogany and seven to...

Embodiment 2

[0074] Composition of traditional Chinese medicine extracts: 12 parts of Hongmuxiang, 30 parts of Sijiqingye, 26 parts of Malan, 20 parts of Tutianqi, and 22 parts of Shuituanhuaye.

[0075] Gel formula: Chinese medicine extract 15%, carbomer 9402.8%, polyvinylpyrrolidone k301.8%, glycerin 6.5%, polysorbate 0.9%, triethanolamine 3.0%, ethylparaben 0.4%, azone 1.5 %, the balance is water;

[0076] Preparation method: Add 8-10 times the amount of water to the ultrafinely pulverized mahogany and Tutianqi, soak for 2-5 hours, and extract the total volatile oil by steam distillation; weigh lecithin, cholesterol (lecithin and cholesterol) The mass ratio is 6.5:1), put it in a round bottom flask, add ether to dissolve it, evaporate the ether under reduced pressure at 50°C, add an appropriate amount of distilled water (so that the concentration of phospholipids is 5.5mg / ml), and incubate at 55°C 20-30min, homogenize with a high-speed dispersing homogenizer, add mahogany and seven tot...

Embodiment 3

[0080] Composition of traditional Chinese medicine extracts: 12 parts of Hongmuxiang, 30 parts of Sijiqingye, 26 parts of Malan, 20 parts of Tutianqi, and 22 parts of Shuituanhuaye.

[0081] Gel formula: Chinese medicine extract 17%, carbomer 9403.5%, polyvinylpyrrolidone k301.5%, glycerin 6.5%, polysorbate 1.1%, triethanolamine 3.4%, ethylparaben 0.35%, azone 2.5 %, the balance is water;

[0082] Preparation method: Add 8-10 times the amount of water to the ultrafinely pulverized mahogany and Tutianqi, soak for 2-5 hours, and extract the total volatile oil by steam distillation; weigh lecithin, cholesterol (lecithin and cholesterol) The mass ratio is 7:1), put it in a round bottom flask, add ether to dissolve it, evaporate the ether under reduced pressure at 60°C, add an appropriate amount of distilled water (so that the concentration of phospholipids is 7.0mg / ml), and incubate at 58°C 20-30min, homogenize with a high-speed dispersing homogenizer, add mahogany and seven tota...

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