Luminous light source device and fetal blood oxygen optical signal acquisition device

Abstract

A luminous light source device and a fetal blood oxygen optical signal collection device are used in an extra-abdominal non-invasive fetal blood oxygen saturation detection device. The luminous light source device includes a luminous light source, and the luminous light source includes a plurality of first light-emitting units and a plurality of second light-emitting units. The plurality of first light-emitting units can all emit red light or infrared light of a first wavelength, and the plurality of second light-emitting units can all emit red light or infrared light of a second wavelength. The first wavelength is different from the second wavelength, and the number of the first light-emitting units and the second light-emitting units is the same. The plurality of first light-emitting units and the plurality of second light-emitting units are arranged into a row and column light source array to achieve large-scale multi-path to increase the luminous power of the light source, so that the received optical signal related to the fetal blood oxygen saturation is greatly enhanced than the original device, but the optical power received per unit area of ​​the pregnant woman's abdominal skin is very small or not increased; the fetal blood oxygen optical signal collection device has the luminous light source device of the present invention.

Description

Technical Field

[0001] The present invention relates to the technical field of blood oxygen saturation detection in medical equipment, and more specifically to a light source device of an extra-abdominal non-invasive fetal blood oxygen saturation detection device and a fetal blood oxygen optical signal acquisition device. Background Art

[0002] Late pregnancy, as well as labor and delivery, can be a dangerous time for both the mother and the fetus. If the fetal umbilical cord becomes twisted and placed in an unfavorable position, the placenta separates prematurely, or certain maternal and fetal diseases occur, the fetus may not have enough oxygen in its blood, which may lead to brain damage or death. 2 ) is used as a physiological indicator to indirectly monitor the human body, including the oxygen content in the fetal blood.

[0003] At present, fetal heart rate and heart sound monitors have been widely used to monitor the physiological status of the fetus. Since the fetus's oxygen supply is not obtained by the fetus's own breathing, but is transported from the placenta by the mother, the fetal blood oxygen saturation can more accurately reflect the oxygen concentration in the blood, and thus is a physiological indicator that more directly reflects the life status of the fetus. 2 The clinical significance of fetal oxygenation is that it directly reflects the oxygenation status of the fetus, thereby confirming the life status of the fetus in the mother's body and reducing perinatal mortality and neonatal disability. In 2000, an American company produced an instrument that placed a sensor in the uterus to measure the fetal blood oxygen saturation. Medical staff need to insert the instrument deep into the uterus of pregnant women and directly draw blood from the surface of the fetus to obtain the fetal blood oxygen saturation index. These methods and instruments are not suitable for long-term and continuous detection of fetal blood oxygen saturation, let alone perinatal monitoring of the fetus. Since there is currently no effective non-invasive instrument to detect fetal blood oxygen saturation, medical staff can often only rely on fetal heart rate monitoring instruments. Although the currently widely used fetal heart rate monitoring can sensitively detect fetal asphyxia, its specificity is low and it cannot reflect the precursors of asphyxia in advance. Due to the low specificity of fetal heart monitoring, doctors lack a full understanding of the overall condition of the fetus. For example, whether a cesarean section is needed and when to start the cesarean section. They must make emergency medical decisions without sufficient knowledge. Therefore, on the one hand, doctors may make wrong diagnoses and miss the opportunity to take necessary measures. On the other hand, doctors are often too cautious, resulting in an increase in many unnecessary cesarean section interventions, which not only increases surgical risks and delivery complications for pregnant women, but the resulting unnecessary high medical expenses also increase the economic burden on society and families.

[0004] The inventor of this patent provides a detection system and method for monitoring fetal pulse oxygen saturation in a non-invasive manner in Chinese patent ZL201310182965.2 (fetal blood oxygen saturation detection system and method). For the first time, a fetal pulse oxygen saturation photoelectric sensor placed outside the pregnant woman's body is used. During the detection process, no operation deep into the pregnant woman's abdomen is required, and the photoelectric sensor does not need to be applied to a specific part of the fetus, thereby truly realizing non-invasive fetal blood oxygen saturation detection outside the abdomen. It can provide two important fetal physiological parameters, the heart rate and the blood oxygen saturation of the fetus, to medical staff at the same time, which has high practical significance for the fetus, pregnant women and society. The present invention is a new invention further generated in the process of developing and realizing specific products based on the above patents. The applicant has found that due to the great uncertainty of the position (fetal position) of the fetus in the mother's uterus, the fetal position of different pregnant women is different, and the fetal position of the same pregnant woman at different stages of pregnancy varies greatly. The posture of the fetus in the uterus will also change at any time, and the blood oxygen saturation of different parts of the fetus is also different. Therefore, when the fetal SaO of the Chinese patent (ZL201310182965.2) is used, the fetal position of the fetus in the uterus will change at any time, and the blood oxygen saturation of different parts of the fetus is also different. 2 When the photoelectric sensor of the detection system is applied to a specific part of the pregnant woman's abdomen, the sensor senses the fetal SaO 2 The relevant photoelectric signal has a large uncertainty, which directly affects the specificity of the test result. That is, when the test result shows a positive (low blood oxygen saturation), the actual SaO 2It is normal. The consequence of this situation may lead to unnecessary human intervention or even surgical intervention, which will increase medical costs and medical risks, and increase the pain of mother and baby. It can be seen that a practical problem faced by non-invasive fetal blood oxygen saturation detection outside the abdomen is how to solve the problem of the uncertainty of fetal position on the test results. Another problem is the attenuation of light. The light signal received by the optical receiver must be a specific wavelength of light that is irradiated from the outside of the pregnant woman's abdomen to the fetus in her abdominal cavity, and then returned from the fetus through the pregnant woman's abdominal cavity to the outside of the pregnant woman's abdomen. It takes a long optical path from emission to reception, and the attenuation of light is proportional to the square of the optical path. In addition, the light signal related to fetal blood oxygen saturation received by the optical receiver is an extremely weak light after complex processes such as absorption, reflection, and scattering by fetal tissue and maternal tissue (such as skin, fat, uterus, amniotic fluid, etc.). Its weakness is enough to threaten the success of the test and the practicality of non-invasive fetal blood oxygen saturation detection outside the abdomen. Therefore, the non-invasive blood oxygen saturation detection device for the extra-abdominal fetus must solve the problem of the strength of the signal related to the fetal blood flow received by the light receiving device, as well as the problem of signal interference, improve the signal strength to remove noise interference, and improve the signal-to-noise ratio. To this end, in order to successfully develop a non-invasive blood oxygen saturation detection device for the extra-abdominal fetus, the above two problems must be solved at the same time. Therefore, the problem of the strength of the signal related to the fetal blood flow received by the light emitting and light receiving device becomes the key to whether these two problems can be solved.

[0005] The applicant also found in the study that the non-invasive blood oxygen saturation monitoring system for the extra-abdominal fetus must have light of sufficient power irradiated on the abdomen of the pregnant woman to ensure that the optical receiver receives effective light signals related to the fetus. However, if the luminous power of the light source is increased blindly, based on the currently used light-emitting elements (such as LEDs and lasers), the luminous area is very small and usually close to the skin of the pregnant woman. There is a possibility that the pregnant woman's skin will feel uncomfortable or be burned during use. According to the document published by the International Commission of Nob-Ionizing Radiation Protection (ICNIRP) in 2000, for LED light waves with a wavelength in the range of 400nm to 1400nm, a few milliwatts of light power for 100 seconds can cause burns to the skin. Therefore, in order to improve the practicality and comfort of the detection device, it is also very necessary to eliminate the risk of light radiation damage caused by local burns. Summary of the invention

[0006] The purpose of the present invention is to provide a light source device for an extra-abdominal non-invasive fetal blood oxygen saturation detection device, which has high light power but low light power received per unit area of ​​pregnant woman's abdominal skin. Furthermore, by reasonably arranging light emitting units that emit red light or infrared light of different wavelengths, the light paths of the light emitting units that pass through the pregnant woman's abdomen to reach the fetus are closer, so as to improve the intensity and accuracy of the signal collected by the light receiving device.

[0007] To achieve the above object, the present invention adopts the following technical solutions:

[0008] A luminous light source device for an extra-abdominal non-invasive fetal blood oxygen saturation detection device includes a luminous light source, wherein the luminous light source includes a plurality of first light-emitting units and a plurality of second light-emitting units, wherein the plurality of first light-emitting units can emit red light or infrared light of a first wavelength, and the plurality of second light-emitting units can emit red light or infrared light of a second wavelength, wherein the first wavelength is different from the second wavelength, the number of the first light-emitting units and the number of the second light-emitting units are the same, and the plurality of first light-emitting units and the plurality of second light-emitting units are arranged into a row and column light source array.

[0009] Furthermore, multiple first light-emitting units arranged at equal or unequal intervals constitute an m*n first row and column light source array, and multiple second light-emitting units arranged at equal or unequal intervals constitute an m*n second row and column light source array, where n is an integer greater than 1 and m is an integer greater than or equal to 1.

[0010] Further, a plurality of first light-emitting units and a plurality of second light-emitting units are arranged at equal or unequal intervals to form an m-row 2*n-column row and column light source array, each column of the row and column light source array is a first light-emitting unit column composed of first light-emitting units or a second light-emitting unit column composed of second light-emitting units, the first light-emitting unit columns and the second light-emitting unit columns are alternately arranged, n is an integer greater than 1, and m is an integer greater than or equal to 1;

[0011] Alternatively, a plurality of first light-emitting units and a plurality of second light-emitting units are arranged at equal or unequal intervals to form a 2*m-row n-column row-column light source array, each row of the row-column light source array is a first light-emitting unit row composed of first light-emitting units or a second light-emitting unit row composed of second light-emitting units, the first light-emitting unit rows and the second light-emitting unit rows are alternately arranged, n is an integer greater than 1 and equal to, and m is an integer greater than 1.

[0012] Furthermore, in a row and column light source array composed of multiple first light-emitting units and multiple second light-emitting units, the first light-emitting units and the second light-emitting units are alternately arranged, so that the first light-emitting units and the second light-emitting units in each row of the row and column light source array are alternately arranged and the first light-emitting units and the second light-emitting units in each column of the row and column light source array are also alternately arranged.

[0013] Furthermore, a light diffusion lens for diffusing the irradiation area is provided outside the light source array formed by the plurality of first light emitting units and the plurality of second light emitting units of the light emitting light source.

[0014] Furthermore, the light diffusion lens is a concave lens, and the distance between the concave lens and the first light-emitting unit and the second light-emitting unit is greater than 0; or, the light diffusion lens is a convex lens, and the distance between the concave lens and the first light-emitting unit and the second light-emitting unit is greater than 0 and less than or equal to the focal length of the convex lens.

[0015] Furthermore, the light source device includes at least two first light emitting units and at least two second light emitting units.

[0016] The present invention also provides a fetal blood oxygen optical signal acquisition device of an extra-abdominal non-invasive fetal blood oxygen saturation detection device, comprising a light sensor mounting mechanism, wherein the light sensor mounting mechanism is integrated with a light source device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device of the present invention and a light receiving device for acquiring optical signals related to fetal blood oxygen saturation from outside the abdomen of a pregnant woman.

[0017] Furthermore, the light receiving device includes a plurality of light receivers respectively arranged at a plurality of different positions outside the abdomen of the pregnant woman and an adder connected to the plurality of light receivers. The light receiving device collects a plurality of light signals related to the fetal blood oxygen saturation scattered and reflected back from the abdomen of the pregnant woman through the plurality of light receivers, and outputs the sum of the light signals related to the fetal blood oxygen saturation after superposition through the adder.

[0018] Furthermore, the multiple light receivers of the light receiving device are arranged around the light source of the light emitting light source device to form a circle.

[0019] The light source device of the present invention adopts a plurality of first light-emitting units and a plurality of second light-emitting units, and arranges the plurality of first light-emitting units and the plurality of second light-emitting units into a row and column light source array with equal spacing, so as to realize large-scale multi-path to increase the light emitting power of the light source, and at the same time, the light illumination is not a single point, so that the received light signal related to the fetal blood oxygen saturation is greatly enhanced compared with the original device, but the light power received per unit area of ​​the pregnant woman's abdominal skin is very small or not increased. In addition, by arranging a light diffusion lens, the light emission angle is expanded, so that when the light emitting power of the light-emitting unit is increased, the light radiation per unit irradiation area is not increased. In particular, in the row and column light source array composed of the plurality of first light-emitting units and the plurality of second light-emitting units, the first light-emitting units and the second light-emitting units are alternately arranged, so that the first light-emitting units and the second light-emitting units in each row of the row and column light source array are alternately arranged and the first light-emitting units and the second light-emitting units in each column of the row and column light source array are also alternately arranged, so that the light paths of the two different wavelengths of red light or infrared light passing through the pregnant woman's abdomen to reach the fetus are closer, and the intensity and accuracy of the signal collected by the light receiving device are greatly improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a structural block diagram of the device for detecting the extra-abdominal non-invasive fetal blood oxygen saturation of the present invention;

[0021] Figure 2 It is a schematic diagram of the structure of the non-invasive fetal blood oxygen saturation detection device outside the abdomen of the present invention;

[0022] Figure 3 It is a structural schematic diagram of the fetal blood oxygen optical signal acquisition device of the present invention;

[0023] Figure 4-5 are structural diagrams of two embodiments of the optical receiving device of the present invention;

[0024] Figure 6-11 It is a structural diagram of six embodiments of the layout structure of multiple optical receivers and light sources of the fetal blood oxygen optical signal acquisition device of the present invention;

[0025] Figure 12-14 are structural diagrams of three embodiments of the layout structure of the light emitting unit of the light emitting light source of the light receiving device of the present invention;

[0026] Fig.15 It is a structural schematic diagram of the luminous light source device of the present invention;

[0027] Fig.16 is a structural diagram of another embodiment of the light receiving device of the present invention;

[0028] Fig.17 yes Fig.16 A block diagram of one embodiment of the signal processing flow of the primary processor 250 is shown;

[0029] Fig.18 yes Fig.16 A block diagram of another embodiment of the signal processing flow of the primary processor 250 is shown;

[0030] Fig.19 yes Fig.16 A block diagram of another embodiment of the signal processing flow of the primary processor 250 is shown;

[0031] Fig. 20 yes Fig.16 An embodiment of an adding selector of a light receiving device;

[0032] Fig.21 yes Fig.16 Another embodiment of an adding selector for a light receiving device. DETAILED DESCRIPTION

[0033] The following is combined with Figures 1 to 21The given examples further illustrate the specific implementation of the extra-abdominal non-invasive fetal blood oxygen saturation detection device of the present invention.

[0034] like Figure 1 As shown, the extra-abdominal non-invasive fetal blood oxygen saturation detection device of the present invention generally includes an extra-abdominal fetal blood oximeter and a signal detection component connected to the extra-abdominal fetal blood oximeter. The extra-abdominal fetal blood oximeter includes a signal processing controller 11; the signal detection component includes a light source device 92 for irradiating two or more different wavelengths of light into the abdomen of a pregnant woman, a light receiving device 91 for collecting light signals related to fetal blood oxygen saturation from outside the abdomen of the pregnant woman, and a reference signal detection device for collecting any one or more of the fetal heart rate signal, the pregnant woman's heart rate signal, and the pregnant woman's pulse blood oxygen saturation light signal. The reference signal detection device includes a fetal heart rate acquisition device for collecting fetal heart rate signals from outside the abdomen of a pregnant woman, and / or a pregnant woman heart rate acquisition device for collecting pregnant woman heart rate signals, and / or a pregnant woman pulse blood oxygen saturation acquisition device for collecting pregnant woman pulse blood oxygen saturation optical signals. The light receiving device 91, the light source device 92, the fetal heart rate acquisition device, the pregnant woman heart rate acquisition device and the pregnant woman pulse blood oxygen saturation acquisition device are all connected to the signal processing controller 11; the signal processing controller 11 calculates the fetal pulse blood oxygen saturation based on the collected optical signals related to the fetal blood oxygen saturation, and based on one or more signals of the fetal heart rate signal, the pregnant woman heart rate signal and the pregnant woman pulse blood oxygen saturation optical signal.

[0035] The present invention relates to a detection technology for measuring the blood oxygen saturation of fetal blood flow outside the body of a pregnant woman. During the detection process, no operation deep into the abdomen of the pregnant woman is required, and no photoelectric sensor is required to be applied to a specific part of the fetus. It has pioneered the realization of non-invasive extra-abdominal non-invasive fetal blood oxygen saturation detection. The specific solution to the problem of how to convert and process signals has been disclosed in the inventor's earlier invention patent CN201310182965.2, which will not be repeated here.

[0036] like Figure 2-3As shown, an embodiment of the extra-abdominal non-invasive fetal blood oxygen saturation detection device of the present invention includes an extra-abdominal fetal blood oximeter and a fetal blood oxygen optical signal acquisition device 9 connected to the extra-abdominal fetal blood oximeter; the extra-abdominal fetal blood oximeter includes a signal processing controller 11, and a display module 12 and an operation module 13 connected to the signal processing controller 11; the fetal blood oxygen optical signal acquisition device 9 includes a light sensor installation mechanism 93, the light sensor installation mechanism 93 is integrated with a light emitting light source device 92 and a light receiving device 91 including a plurality of light receivers 204, and the light emitting light source device 92 and the light receiving device 91 are integrated together to form a collection device for collecting fetal blood oxygen optical signals. The fetal blood oxygen optical signal acquisition device 9 can wrap the light emitting light source device 92 and the light receiving device 91 tightly on the surface of the pregnant woman's abdomen in a close manner, and can be adjusted according to the movement position of the fetus; preferably, the fetal blood oxygen optical signal acquisition device 9 is a soft member wrapped around the pregnant woman's abdomen that can be fixedly installed with the light emitting light source device 92 and the light receiving device 91 including a plurality of light receivers 204 and can be fixed on the pregnant woman's abdomen at the same time. For example, the optical sensor mounting mechanism 93 of the fetal blood oxygen optical signal acquisition device 9 can be a belt tied around the abdomen of a pregnant woman, a wearable abdominal scarf, a belly band or other devices that can be installed with a light source device 92 and a light receiving device 91 including multiple light receivers 204 and can be fixed on the abdomen of a pregnant woman. The fetal blood oxygen optical signal acquisition device 9 is connected to the extra-abdominal fetal blood oximeter via a communication link 14, and the communication link 14 can be a wired link or a wireless link. The wireless link can use WIFI, Bluetooth and other wireless communication protocols. The display module 12 can be an LED screen, an LCD screen or a touch screen, and the operation module 13 can be a keyboard.

[0037] Furthermore, the extra-abdominal non-invasive fetal blood oxygen saturation detection device also includes a fetal heart rate collection device (not shown in the figure). The fetal blood oxygen optical signal collection device 9 is combined with the fetal heart rate collection device to form an extra-abdominal fetal blood oxygen probe, or the fetal heart rate collection device is also integrated on the optical sensor mounting mechanism 93 of the fetal blood oxygen optical signal collection device 9 to form an extra-abdominal fetal blood oxygen probe, which is used to collect various signals required by the extra-abdominal fetal blood oxygen meter. The extra-abdominal fetal blood oxygen probe is connected to the extra-abdominal fetal blood oxygen meter 1 via a communication link 14. For example, in one embodiment, the fetal blood oxygen optical signal acquisition device 9 and the fetal heart acquisition device are two independent acquisition devices, which together constitute an extra-abdominal fetal blood oxygen probe. The fetal blood oxygen optical signal acquisition device 9 and the fetal heart acquisition device are respectively connected to the extra-abdominal fetal blood oxygen meter 1. The extra-abdominal fetal blood oxygen meter 1 is provided with an optical signal interface connected to the optical receiving device 91, a light source interface connected to the light source device 92, and a fetal heart rate detection interface connected to the fetal heart acquisition device. The light source device 92, the light receiving device 91 and the fetal heart acquisition device are respectively connected to the optical signal interface, the light source interface and the fetal heart rate detection interface through an optical signal link, a light source link and a fetal heart rate signal link. The optical signal link, the light source link and the fetal heart rate signal link can be wired or wireless links. The wireless link can use WIFI, Bluetooth and other wireless communication protocols. For example, another embodiment is that the light source device 92 and the light receiving device 91 of the fetal blood oxygen optical signal acquisition device 9, and the fetal heart acquisition device are integrated on the optical sensor mounting mechanism 93 to form an extra-abdominal fetal blood oxygen probe, and the extra-abdominal fetal blood oxygen meter 1 is provided with a first wireless transmitter and receiver, and the optical signal interface, the light source interface and the fetal heart rate detection interface of the extra-abdominal fetal blood oxygen meter 1 are respectively connected to the first wireless transmitter and receiver, and the optical sensor mounting mechanism 93 is provided with a second wireless transmitter and receiver, and the light source device 92, the light receiving device 91 and the fetal heart acquisition device are respectively connected to the second wireless transmitter and receiver, and are connected to the extra-abdominal fetal blood oxygen meter 1 through the link of the second wireless transmitter and receiver and the first wireless transmitter and receiver. Further, the extra-abdominal fetal blood oxygen probe can also include a pregnant woman's heart rate acquisition device and / or a pregnant woman's pulse blood oxygen saturation acquisition device (not shown in the figure).

[0038] One of the improvements of the present invention is that the signal processing controller 11 controls the light source device 92 to irradiate two or more different wavelengths of light into the abdomen of the pregnant woman, and the light receiving device 91 includes a plurality of light receivers 204 respectively arranged at a plurality of different positions outside the abdomen of the pregnant woman, and the light receiving device 91 collects a plurality of light signals related to fetal blood oxygen saturation scattered and reflected from the abdomen of the pregnant woman through the plurality of light receivers 204, and outputs the sum of the light signals related to fetal blood oxygen saturation after superposition to the signal processing controller 11. The light receiving device 91 of the present invention includes a plurality of light receivers 204 respectively arranged at a plurality of different positions outside the abdomen of the pregnant woman, and the light receiving device 91 collects a plurality of light signals related to fetal blood oxygen saturation returned from the abdomen of the pregnant woman, and superpositions and summarizes the sum of the light signals to transmit to the signal processing controller 11; the signal processing controller 11 calculates the fetal blood oxygen saturation according to the sum of the light signals output by the light receiving device 91 and any one or more of the fetal heart rate signal, the pregnant woman heart rate signal and the pregnant woman pulse blood oxygen saturation light signal collected from the reference signal detection device. The optical receiving device 91 of the present invention collects multiple optical signals related to fetal blood oxygen saturation through multiple optical receivers 204, and superimposes and summarizes the collected multiple signals and transmits them to the signal processing controller 11, effectively improving the intensity of the optical signal related to fetal blood flow in the received signal. The optical receiver 204 is a silicon photodiode, an avalanche photodiode, a photomultiplier tube or other photoelectric conversion device; the luminous illumination module 12 includes at least two light sources with different wavelengths, which can be red light of 500 nanometers to infrared light of 1000 nanometers, preferably 660 nanometers, 740 nanometers, 880 nanometers, and 940 nanometers, and the luminous light source is an LED or a laser or other luminous light source.

[0039] like Figure 4-5 As shown, the optical receiving device 91 includes a plurality of optical receivers 204 and an adder connected to the plurality of optical receivers 204, and the adder is connected to the signal processing controller 11 of the extra-abdominal fetal oximeter. Each optical receiver 204 receives an optical signal related to the fetal blood oxygen saturation returned from the abdomen of a pregnant woman, and converts each optical signal into a multi-channel electrical signal. The adder superimposes the multi-channel electrical signals and outputs the sum of the optical signals related to the fetal blood oxygen saturation to the signal processing controller 11. The optical receiving device 91 is implemented by a plurality of optical receivers 204 and the adder, and has a simple structure and low cost, and does not require improvement of the existing extra-abdominal fetal oximeter.

[0040] like Figure 4As shown, an embodiment of the optical receiving device 91 of the present invention, the optical receiving device 91 includes a plurality of optical receivers 204, a plurality of amplifiers respectively connected to the plurality of optical receivers 204, the plurality of amplifiers are connected to an adder, and the adder is connected to the signal processing controller 11 of the extra-abdominal fetal oximeter through a digital-to-analog converter. Each optical receiver 204 receives an optical signal related to the fetal blood oxygen saturation returned from the abdomen of a pregnant woman, and converts each optical signal into a multi-channel electrical signal, which is put into the amplifier, superimposed together by an adder, and then outputted to the signal processing controller 11 as a sum of optical signals of a digital signal of a digital-to-analog converter.

[0041] like Figure 5 As shown, another embodiment of the optical receiving device 91 of the present invention, the optical receiving device 91 includes a plurality of optical receivers 204, a plurality of amplifiers respectively connected to the plurality of optical receivers 204, a plurality of digital-to-analog converters respectively connected to the plurality of amplifiers, the plurality of digital-to-analog converters are connected to an adder, and the adder is connected to the signal processing controller 11 of the extra-abdominal fetal oximeter. After each optical receiver 204 converts each optical signal into a multi-channel electrical signal, the signal is amplified by the amplifier and converted into a digital signal by the digital-to-analog converter, and then superimposed into a total optical signal by the adder and output to the signal processing controller 11.

[0042] One of the improvements of the present invention is that the fetal blood oxygen optical signal acquisition device 9 integrates the light emitting light source device 92 and the light receiving device 91 including multiple light receivers 204, which not only makes it easy to use, but also makes the layout between the light emitting light source device 92 and the multiple light receivers 204 more reasonable, and the paths for collecting scattering and reflection are closer, so that the light source can be reasonably utilized and the signal strength collected by the light receiving device 91 is improved.

[0043] like Figure 6 As shown, a preferred embodiment of the fetal blood oxygen optical signal acquisition device 9 of the present invention is shown, wherein the multiple light receivers 204 of the light receiving device 91 and the light emitting light source device 92 are mounted on the sensor mounting mechanism 93, and the multiple light receivers 204 of the light receiving device 91 are arranged around the light emitting light source 921 of the light emitting light source device 92 to form a circle. Preferably, the light sensor mounting mechanism 93 can be formed into a circular arch and buckled on the abdomen of a pregnant woman, the light emitting light source of the light emitting light source device 92 is located in the middle of the circular arch and located in the middle of the top side of the pregnant woman's abdomen, the multiple light receivers 204 of the light receiving device 91 surround the side of the pregnant woman's abdomen to form a circle, and the light emitting light source and the multiple light receivers 204 form a circular arch. By reasonably arranging the multiple light receivers 204 of the light receiving device 91 and the light emitting light source 921 of the light emitting light source device 92, the light source can be reasonably utilized, and the signal strength collected by the light receiving device 91 can be improved.

[0044] like Figure 7As shown, another preferred embodiment of the fetal blood oxygen optical signal acquisition device 9 of the present invention, the multiple light receivers 204 of the light receiving device 91 are arranged around the light source 921 of the light source device 92 to form a square.

[0045] like Figure 8-11 In the several embodiments shown, the multiple light receivers 204 of the light receiving device 91 form an array of i rows and j columns and are arranged on one side of the light source 921 of the light emitting light source device 92, and i and j are both integers greater than 0; or the multiple light receivers 204 of the light receiving device 91 form two arrays of i rows and j columns and are respectively arranged on both sides of the light source 921 of the light emitting light source device 92, and i and j are both integers greater than 0.

[0046] Furthermore, another preferred embodiment of the fetal blood oxygen optical signal acquisition device 9 of the present invention includes a conduction switch controlled by a signal generated by a pulse timing emitted by the light emitting light source device 92. The optical signal received by each optical receiver 204 of the optical receiving device 91 is converted into an electrical signal and then passed through the conduction switch, so that the light emission of the light emitting light source device 92 and the optical signal received by the conduction switch are synchronized. Only the optical signal within a narrow pulse time synchronized with the light emission of the light emitting light source device 92 can be sent to the analog-to-digital converter of the optical receiving device 91 and converted into a digital signal for further processing.

[0047] One of the improvements of the present invention is that the luminous light source device 92 of the present invention includes a luminous light source 921 and a light source driver connected to the luminous light source 921. The light source driver is connected to the signal processing controller, and the light source driver drives the luminous light source 921 to emit a pulse light with a frequency higher than 20Hz under the control of the signal processing controller, and the duty cycle of its pulse is less than 40%. The preferred frequency range of the pulse light is 400Hz to 5000Hz, but does not include frequencies of 50Hz, 60Hz and integer multiples thereof. The luminous light source device 92 of the present invention uses a pulse light signal with a small duty cycle, so that the average light power received by the human body is much smaller than the instantaneous maximum luminous power, thereby ensuring human safety. While improving the signal strength, it solves the problem that excessive luminous power may cause harm to pregnant women and fetuses. The light source driver of this embodiment can be used for a luminous light source 921 having a single first light-emitting unit and a single second light-emitting unit, and can also be used for a luminous light source 921 having multiple first light-emitting units and multiple second light-emitting units.

[0048] One of the improvements of the present invention is that the luminous light source device of the present invention includes a luminous light source 921 and a light source driver connected to the luminous light source 921, the luminous light source 921 includes a plurality of first light-emitting units and a plurality of second light-emitting units, the plurality of first light-emitting units are all capable of emitting red light or infrared light of a first wavelength, the plurality of second light-emitting units are all capable of emitting red light or infrared light of a second wavelength, the first wavelength is different from the second wavelength, the number of first light-emitting units and the number of second light-emitting units are the same, the plurality of first light-emitting units and the plurality of second light-emitting units are arranged into a row and column light source array, and the plurality of first light-emitting units and the plurality of second light-emitting units are alternately lit under the control of the light source driver. The plurality of first light-emitting units and the plurality of second light-emitting units in the row and column light source array may be equally spaced or unequally spaced, and preferably, the spacing between the light-emitting units in the row and column light source array is equal. The light emitting light source device 92 of the present invention adopts a plurality of first light emitting units and a plurality of second light emitting units, and arranges the plurality of first light emitting units and the plurality of second light emitting units into a light source array with equal spacing in rows and columns, so as to realize large-scale multi-path to increase the light emitting power of the light source, and at the same time, the light illumination is not one point, so that the received light signal related to the fetal blood oxygen saturation is greatly enhanced than the original device, but the light power received per unit area of ​​the pregnant woman's abdominal skin is very small or not increased. Preferably, the light emitting light source device 92 includes at least 2 first light emitting units and at least 2 second light emitting units. The first light emitting unit and the second light emitting unit are LEDs, lasers or other light sources that can emit red light or infrared light, preferably LEDs or lasers that can emit 600 nanometers of red light to 950 nanometers of infrared light. If the first wavelength is red light, the second wavelength is infrared light, and if the first wavelength is infrared light, the second wavelength is red light. It is best that the first wavelengths of the red light or infrared light emitted by the multiple first light-emitting units are completely identical, but this is difficult to achieve in practice. Therefore, the first wavelengths of the red light or infrared light emitted by the multiple first light-emitting units are basically the same, and within a small deviation range, and all fall within the protection scope of this application. Similarly, the second wavelengths of the red light or infrared light emitted by the multiple second light-emitting units are also similar.

[0049] like Fig.12 As shown, the light source 921 of the light source device 92 includes a plurality of first light emitting units arranged at equal or unequal intervals to form an m*n first row and column light source array, and a plurality of second light emitting units arranged at equal or unequal intervals to form an m*n second row and column light source array, where n is an integer greater than 1, and m is an integer greater than or equal to 1. The first light emitting unit is a red light LED 102, where R represents red light, and the first row and column light source array is a red light LED array composed of red light LEDs, and the second light emitting unit is an infrared light LED 104, where IR represents infrared light, and the second row and column light source array is an infrared light LED array composed of infrared light LEDs.

[0050] like Fig.13 As shown, the light source of the light emitting light source device includes a plurality of first light emitting units and a plurality of second light emitting units arranged at equal or unequal intervals to form a row-column light source array of m rows and 2*n columns, each column of the row-column light source array is a first light emitting unit column composed of first light emitting units or a second light emitting unit column composed of second light emitting units, the first light emitting unit columns and the second light emitting unit columns are alternately arranged, n is an integer greater than 1, m is an integer greater than or equal to 1, and the optical path ratio of the two red lights or infrared lights of different wavelengths passing through the abdomen of the pregnant woman to reach the fetus is Fig.12 Obviously, it is also possible to arrange the first light-emitting unit and the second light-emitting unit in an alternating manner, that is, a plurality of first light-emitting units and a plurality of second light-emitting units are arranged at equal intervals or at unequal intervals to form a row-column light source array of 2*m rows and n columns, each row of the row-column light source array is a first light-emitting unit row composed of first light-emitting units or a second light-emitting unit row composed of second light-emitting units, the first light-emitting unit rows and the second light-emitting unit rows are alternately arranged, n is an integer greater than 1 and equal to, and m is an integer greater than 1.

[0051] like Fig.14 As shown in the preferred embodiment of the light emitting light source device of the present invention, in a row and column light source array composed of a plurality of first light emitting units and a plurality of second light emitting units, the first light emitting units and the second light emitting units are alternately arranged, so that the first light emitting units and the second light emitting units in each row of the row and column light source array are alternately arranged and the first light emitting units and the second light emitting units in each column of the row and column light source array are also alternately arranged, so that the optical path of two red lights or infrared lights of different wavelengths passing through the abdomen of a pregnant woman to reach the fetus is shorter than Fig.13 Being closer, the intensity and accuracy of the signal collected by the light receiving device 91 are greatly improved.

[0052] Further, if Fig.15 As shown, in a preferred embodiment of the luminous light source device of the present invention, a light diffusion lens 922 for diffusing the irradiation area is provided outside the row and column light source array formed by the plurality of first luminous units and the plurality of second luminous units of the luminous light source 921, so as not to increase the light radiation per unit irradiation area when the luminous power of the luminous unit is increased. Preferably, the light diffusion lens 922 is a concave lens, and the distance between the concave lens and the first luminous unit and the second luminous unit is greater than 0; or, the light diffusion lens is a convex lens, and the distance between the concave lens and the first luminous unit and the second luminous unit is greater than 0 and less than or equal to the focal length of the convex lens.

[0053] Further, a preferred embodiment of the fetal blood oxygen optical signal acquisition device of the present invention combines the light receiving device 91 of the present invention including multiple light receivers 204 with a light emitting light source device 92 arranged in a row and column light source array. As a preferred embodiment, the light receiving device 91 and the light emitting light source device 92 are installed on the light sensor mounting mechanism 93, and the light emitting light source of the light emitting light source device 92 includes a row and column light source array composed of multiple first light emitting units and multiple second light emitting units. In the row and column light source array, the first light emitting unit and the second light emitting unit are alternately arranged, so that the first light emitting unit and the second light emitting unit in each row of the row and column light source array are alternately arranged and the first light emitting unit and the second light emitting unit in each column of the row and column light source array are also alternately arranged, and the multiple light receivers 204 of the light receiving device 91 are arranged around the light emitting light source device 92 to form a circle, and the light sensor mounting mechanism 93 can form a circular arch buckle on the abdomen of the pregnant woman, and the light emitting light source of the light emitting light source device 92 is located in the middle of the circular arch, located in the middle of the top side of the pregnant woman's abdomen, and the multiple light receivers 204 of the light receiving device 91 surround the side of the pregnant woman's abdomen to form a circle, and the light emitting light source and the multiple light receivers 204 form a circular arch. This makes the illumination of the light source and the collection of the light receiver 204 multi-point and does not require a one-to-one correspondence, thereby increasing the unit area. In addition, the optical paths of the two different wavelengths of red light or infrared light passing through the abdomen of the pregnant woman to reach the fetus are close, which greatly improves the intensity of the optical signal related to the fetal blood flow in the received signal.

[0054] like Fig.16 As shown, another improvement of the present invention is that the optical receiving device 91 of the present invention includes multiple optical receivers 204, and a signal primary processor 250 connected to the multiple optical receivers 204. The signal primary processor 250 includes an interface for receiving a fetal heart rate signal, which is used to connect to a fetal heart rate acquisition device. The primary processor 250 receives multiple optical signals related to fetal blood oxygen saturation through the multiple optical receivers 204, and obtains the fetal heart rate signal collected simultaneously through the fetal heart rate acquisition device. The primary processor 250 performs correlation analysis on the received multiple optical signals related to fetal blood oxygen saturation with the fetal heart rate signal to obtain a correlation coefficient of each optical signal; obtains a weighting coefficient corresponding to each optical signal based on the correlation coefficient; and superimposes the multiple optical signals according to their respective weighting coefficients to obtain the sum of the optical signals.

[0055] The present invention also provides a method for processing an extra-abdominal non-invasive fetal blood oxygen saturation detection signal, which synthesizes a plurality of received optical signals containing fetal blood oxygen saturation information into a sum of optical signals to increase the intensity of the optical signal related to the fetal blood oxygen saturation, removes noise interference, and improves the signal-to-noise ratio. The method can be used in an optical receiving device 91, and comprises the following steps:

[0056] The received multiple optical signals related to fetal blood oxygen saturation are respectively correlated with the fetal heart rate signal to obtain the correlation coefficient of each optical signal; based on the correlation coefficient, the weighting coefficient corresponding to each optical signal is obtained; and the multiple optical signals are superimposed according to their respective weighting coefficients to obtain the sum of the optical signals. Among them, the step of obtaining the weighting coefficient corresponding to each optical signal based on the correlation coefficient is: if the correlation coefficient of the optical signal is lower than the preset correlation threshold, the optical signal is discarded, that is, the weighting coefficient is 0; if the correlation coefficient is higher than the preset correlation threshold, the weighting coefficient is obtained according to the correlation coefficient, the larger the correlation coefficient, the larger the weighting coefficient, 0<weighting coefficient<1; then, the multiple optical signals are superimposed according to their respective weighting coefficients to obtain the sum of the optical signals, such as multiplying the multiple optical signals by their respective weighting coefficients and superimposing them to obtain the sum of the optical signals. The present invention provides an extra-abdominal non-invasive fetal blood oxygen saturation signal processing method, which collects multiple light signals related to fetal blood oxygen saturation through multiple light receivers 204 and superimposes the synthesized light signal sum to improve the intensity of the received light signal, and performs weighted superposition based on correlation analysis between the light signals collected by the multiple light receivers 204 and the fetal heart rate signals collected at the same time to remove noise signal interference in the light signal that is not related to fetal blood oxygen saturation, thereby improving the signal-to-noise ratio of the collected light signal, thereby improving the accuracy and reliability of the detection of the extra-abdominal non-invasive fetal blood oxygen saturation detection device.

[0057] The method for processing signals for detecting extra-abdominal non-invasive fetal blood oxygen saturation of the present invention can be used on the optical receiving device 91 of the extra-abdominal non-invasive fetal blood oxygen saturation detection device, and the sum of optical signals related to fetal blood oxygen saturation is obtained by selectively superimposing the received multiple optical signals related to fetal blood oxygen saturation, removing noise interference, and improving the signal-to-noise ratio, and then the sum of optical signals related to fetal blood oxygen saturation is sent to the signal processing controller 11 of the extra-abdominal fetal oximeter 1, and the signal processing controller 11 analyzes and calculates the sum of optical signals and the fetal heart rate signal to obtain the fetal blood oxygen saturation. Of course, the signal processing controller 11 can further analyze and calculate the fetal blood oxygen saturation based on the sum of optical signals, the collected pregnant woman's heart rate, and / or the pregnant woman's optical signal, and / or the fetal heart rate signal. The calculation method of the fetal blood oxygen saturation has been recorded in another patent of the inventor, CN201310182965.2, and will not be repeated here. It should be noted that the extra-abdominal non-invasive fetal blood oxygen saturation detection signal processing method of the present invention can also be processed by the signal processing controller 11, which receives multiple optical signals and synthesizes the sum of the optical signals, but this will greatly increase the complexity of the system.

[0058] like Fig.16As shown, the optical receiving device 91 of the present invention includes a plurality of optical receivers 204, a plurality of amplifiers respectively connected to the plurality of optical receivers 204, a plurality of digital-to-analog converters respectively connected to the plurality of amplifiers, and a signal primary processor 250 connected to the plurality of digital-to-analog converters, and the signal primary processor 250 is connected to the output end of the fetal heart acquisition device. Each optical receiver 204 receives the optical signal from the abdomen of the pregnant woman and converts it into a multi-channel electrical signal, which is processed into a multi-channel digital signal by the amplifier and the analog-to-digital converter, and then processed by the signal primary processor 250 to synthesize the total received optical signal 256.

[0059] An example of an implementation of the signal primary processor 250 is as follows: Fig.16 As shown, it includes multiple signal analyzers 252 and an addition selector 254 connected to the multiple signal analyzers 252, the multiple signal analyzers 252 perform correlation analysis, and the addition selector 254 performs signal selection and superposition. Of course, the signal primary processor 250 can be a single-chip microcomputer. The extra-abdominal non-invasive fetal blood oxygen saturation detection signal processing method of the present invention is implemented by software, including the corresponding functions of the signal analyzer 252 and the addition selector 254 are implemented by software, and the single-chip microcomputer executes the corresponding software to analyze, process and superimpose multiple optical signals to achieve the synthesis of the sum of optical signals. The fetal heart rate sensor of the fetal heart acquisition device can be a Doppler ultrasonic fetal heart sound sensor or a fetal electrocardiogram sensor composed of electrodes or other fetal heart rate sensors. As another embodiment, the signal primary processor 250 can be a single-chip microcomputer, replacing the Figure 4-5 The adder of the embodiment shown implements Figure 4-5 In the embodiment shown, the signal superposition is performed directly by software.

[0060] Fig.17 This is an example of a process in which a signal analyzer 252 performs signal analysis in the time domain. The signal analyzer 252 is a time domain signal analyzer, which performs correlation analysis on each received optical signal related to fetal blood oxygen saturation and the received fetal heart rate signal in the time domain to obtain the correlation coefficient of each optical signal. Fig.17 The process of weighting and superimposing the digital signal of multiple optical signals to synthesize the sum of the received optical signals 256 in the method for processing the signal of the extra-abdominal non-invasive fetal blood oxygen saturation detection of the present invention comprises the following steps:

[0061] (620) acquiring an optical signal received by an optical receiver, converting the optical signal received by the optical receiver into an electrical signal, and then converting the electrical signal into a digital signal after being processed by an amplifier and a digital-to-analog converter, thereby obtaining an optical signal related to fetal blood oxygen saturation;

[0062] (630) In parallel with step (620), obtaining a fetal heart rate signal received by a fetal heart rate acquisition device;

[0063] (622) performing correlation analysis between the optical signal and the fetal heart rate signal in the time domain. The correlation analysis algorithm belongs to the prior art and is recorded in general mathematics manuals, which will not be described in detail here.

[0064] (624) The correlation coefficient A is calculated through correlation analysis;

[0065] (626) determining whether the correlation coefficient A exceeds a preset threshold value X, if the correlation coefficient A is higher than the preset threshold value X, proceeding to step 628, if the correlation coefficient A is lower than the preset threshold value X, proceeding to step 632;

[0066] (628) Obtain a weighting coefficient M according to the correlation coefficient A, 0<weighting coefficient M<1, and then go to the next step 634;

[0067] (632) Set the weighting coefficient M to 0, and then go to the next step 634;

[0068] (634) The optical signal related to the fetal blood oxygen saturation is multiplied by the weighting coefficient M and weighted, and the weighted data E is sent to the addition selector 254.

[0069] Fig.18 This is an example of a process in which a signal analyzer 252 performs signal analysis in the frequency domain. The signal analyzer 252 is a frequency domain signal analyzer. Each received optical signal related to fetal blood oxygen saturation is converted from the time domain to the frequency domain to obtain an optical signal spectrum. At the same time, the received fetal heart rate signal is converted from the time domain to the frequency domain to obtain a fetal frequency domain optical power spectrum. The optical signal spectrum is correlated with the fetal frequency domain optical power spectrum in the frequency domain to obtain the correlation coefficient of each optical signal. For details, see Fig.18 The process of weighting and superimposing multiple digital signals to synthesize the sum of received optical signals 256 in the method for processing signals of extra-abdominal non-invasive fetal blood oxygen saturation detection of the present invention comprises the following steps:

[0070] (720) acquiring an optical signal received by the optical receiver, converting the optical signal received by the optical receiver into an electrical signal, and then converting the electrical signal into a digital signal after being processed by an amplifier and a digital-to-analog converter, thereby obtaining an optical signal related to the fetal blood oxygen saturation, and then proceeding to the next step 722;

[0071] (722) converting the optical signal related to the fetal blood oxygen saturation from the time domain to the frequency domain to obtain an optical signal spectrum, and then proceeding to step 724;

[0072] (740) In parallel with step 720, obtain the fetal heart rate signal received by the fetal heart rate acquisition device, and then go to the next step 742;

[0073] (742) converting the input fetal heart rate signal from the time domain to the frequency domain to obtain the fetal frequency domain optical power spectrum, and then proceeding to the next step 724;

[0074] (724) performing correlation analysis on the optical signal spectrum related to fetal blood oxygen saturation and the fetal frequency domain optical power spectrum in the frequency domain;

[0075] (726) calculating, through correlation analysis, a relative value B between the optical signal spectrum and the fetal frequency domain optical power spectrum in the frequency domain as a correlation coefficient;

[0076] (728) Determine whether the relative value B exceeds a preset threshold value Y. If the relative value B is higher than the preset threshold value Y, go to step 730. If the relative value B is lower than the preset threshold value Y, go to step 744.

[0077] (730) restore the optical signal spectrum from the frequency domain back to the time domain, and then go to the next step 732;

[0078] (732) weighting according to the relative value B to obtain a weighting coefficient M, 0<weighting coefficient M<1, and then go to the next step 734;

[0079] (744) Restore the spectrum signal of the optical signal from the frequency domain back to the time domain, and then go to the next step 746. Of course, step 744 can also be omitted;

[0080] (746) Set the weighting coefficient M to 0, and then go to the next step 734;

[0081] (734) The optical signal related to the fetal blood oxygen saturation is weighted with the weighting coefficient M, and the weighted data F is sent to the addition selector 254.

[0082] Fig.19 This is another process example of a signal analyzer 252 performing signal analysis in the frequency domain. Each received optical signal related to fetal blood oxygen saturation is converted from the time domain to the frequency domain to obtain an optical signal spectrum. At the same time, the received fetal heart rate signal is converted from the time domain to the frequency domain to obtain a fetal frequency domain optical power spectrum. The optical signal spectrum is correlated with the fetal frequency domain optical power spectrum in the frequency domain to obtain the correlation coefficient of each optical signal. The signal spectrum power other than the fetal spectrum power is filtered out from the optical signal spectrum to obtain a filtered optical signal spectrum, so as to remove the noise signal interference in the optical signal that is not related to the fetal blood oxygen saturation. The filtered optical signal spectrum is then restored from the frequency domain back to the time domain to obtain a filtered optical signal as a weighted superposition optical signal. For details, see Fig.19 The process of weighting and superimposing multiple digital signals to synthesize the sum of received optical signals 256 in the method for processing signals of extra-abdominal non-invasive fetal blood oxygen saturation detection of the present invention comprises the following steps:

[0083] (720) acquiring an optical signal received by the optical receiver, converting the optical signal received by the optical receiver into an electrical signal, and then converting the electrical signal into a digital signal after being processed by an amplifier and a digital-to-analog converter, thereby obtaining an optical signal related to the fetal blood oxygen saturation, and then proceeding to the next step 722;

[0084] (722) converting the optical signal related to the fetal blood oxygen saturation from the time domain to the frequency domain to obtain the optical signal spectrum, and then proceeding to the next step 724;

[0085] (740) In parallel with step 720, obtain the fetal heart rate signal received by the fetal heart rate acquisition device, and then go to the next step 742;

[0086] (742) converting the input fetal heart rate signal from the time domain to the frequency domain to obtain the fetal frequency domain optical power spectrum, and then proceeding to the next step 724;

[0087] (724) performing correlation analysis and comparison between the optical signal spectrum related to fetal blood oxygen saturation and the fetal frequency domain optical power spectrum in the frequency domain;

[0088] (726) calculating, through correlation analysis, a relative value B between the optical signal spectrum and the fetal frequency domain optical power spectrum in the frequency domain as a correlation coefficient;

[0089] (728) Determine whether the relative value B exceeds a preset threshold value Y. If the relative value B is higher than the preset threshold value Y, go to step 750. If the relative value B is lower than the preset threshold value Y, go to step 744.

[0090] (750) Filter out the signal spectrum power other than the fetal frequency domain optical power spectrum from the optical signal spectrum to obtain a filtered optical signal spectrum, which can be implemented by using a frequency domain filter or by software, and then go to the next step 730

[0091] (730) restore the spectrum of the filtered optical signal from the frequency domain back to the time domain to obtain the filtered optical signal as the weighted superposition optical signal, and then go to the next step 734;

[0092] (744) restore the optical signal spectrum from the frequency domain back to the time domain, and then go to the next step 746;

[0093] (746) multiply by the weighting coefficient M to 0, and then go to the next step 734;

[0094] (734) The filtered optical signal related to the fetal blood oxygen saturation is weighted with the weighting coefficient M, and the weighted data F is sent to the addition selector 254.

[0095] It should be noted that Fig.18 and Fig.19The difference is that after the frequency domain signal is determined to exceed the preset threshold value Y in step 728, Fig.18 In step 730, inverse transformation is directly performed to restore the time domain signal. Fig.19 After filtering out the signal irrelevant to the fetal frequency domain optical power spectrum, the signal is input into step 730 for inverse conversion to restore the time domain signal.

[0096] Fig.18 , Fig.19 In step 722, the mathematical conversion formula for converting the signal from the time domain to the frequency domain can adopt the fast Fourier transform formula or the Z transform formula. In addition, the Laplace transform can also be used for the conversion from the time domain to the frequency domain. The method of converting the time domain to the frequency domain belongs to the existing technology and will not be repeated here.

[0097] Fig.18 , Fig.19 In step 730, the mathematical conversion formula for inversely converting the signal from the frequency domain back to the time domain can correspond to the fast inverse Fourier transform formula and the inverse Z transform formula or the inverse Laplace transform. The method of inversely converting the frequency domain back to the time domain belongs to the prior art and will not be repeated.

[0098] See also Fig.16 , 20 -21, the signal primary processor 250 also includes a time-frequency converter for converting the digital signal from the time domain to the frequency domain and / or a time-frequency inverse converter for restoring the digital signal from the frequency domain to the time domain. The signal analyzer 252 of the signal primary processor 250 respectively marks the weighting coefficients of each digital signal based on the correlation between the fetal heart rate signal and the digital signal in the frequency domain or the time domain, and the addition selector 254 performs superposition processing according to the weighting coefficients. The addition selector 254 can be a linear adder or an optical signal selector.

[0099] Fig. 20 yes Fig.16 The signal primary processor 250 includes an adder selector 254, which is a linear adder, which linearly adds the multi-channel digital signals output by the optical receiver 204 and analyzed and processed by the signal analyzer 252 to synthesize the total received light signal 256. Specifically, the signals 802, 804, 806 generated by each signal analyzer 252 are merged into the linear adder for linear addition to generate the total received light signal 256. The total received light signal 256 will be sent to the extra-abdominal fetal blood oximeter 1 through the communication link 14. The input signal of the linear adder of the signal primary processor 250 is the data E generated by the time domain signal analyzer, or the data F generated by the frequency domain signal analyzer.

[0100] Fig.21 yes Fig.16Another process example of the addition selector 254 in the signal primary processor 250. The signal primary processor 250 includes the addition selector 254, which is an optical signal selector. It selects one of the multiple digital signals output by the optical receiver 204 and analyzed and processed by the signal analyzer 252 as the received optical signal sum 256; or selects multiple digital signals from them and superimposes them to form the received optical signal sum 256. Specifically, the signals 802, 804, 806 generated by each signal analyzer are fed into the optical signal selector for further screening and superposition. The optical signal selector 810 compares and selects all the signals 802, 804, 806. Figure 6 , Figure 7 , Fig.16 The position of each optical receiver 204 in the signal primary processor 250 is recognized, and other knowledge related to fetal blood oxygen saturation is judged, and one or more signals are selected to generate the total received optical signal 256. The total received optical signal 256 is sent to the extra-abdominal fetal blood oximeter 1 through the communication link 14. The input signal of the optical signal selector of the signal primary processor 250 is the data E generated by the time domain signal analyzer, or the data F generated by the frequency domain signal analyzer. The selection conditions of the optical signal selector of the signal primary processor 250 include the blood oxygen saturation signal state and / or the position signal state.

[0101] The present invention can be used for fetuses with hypoxia and poor heart rate, as well as fetuses with normal heart rate. It can be tested in hospitals, or transplanted and expanded to remote perinatal monitoring supported by mobile Internet, such as remote testing at home. The present invention can be combined with existing electronic fetal monitors (EFM) to achieve signal processing for more comprehensive new fetal monitoring equipment.

[0102] The above contents are further detailed descriptions of the present invention in combination with specific preferred embodiments, and it cannot be determined that the specific implementation of the present invention is limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as falling within the protection scope of the present invention.

Claims

1. A fetal blood oxygen optical signal acquisition device for an extra-abdominal non-invasive fetal blood oxygen saturation detection device, characterized in that: It comprises a light sensor installation mechanism, wherein the light sensor installation mechanism is integrated with a light source device and a light receiving device for collecting light signals related to fetal blood oxygen saturation from outside the abdomen of a pregnant woman, wherein the light source device comprises a light source, wherein the light source comprises a plurality of first light emitting units and a plurality of second light emitting units, wherein the plurality of first light emitting units are capable of emitting red light or infrared light of a first wavelength, wherein the plurality of second light emitting units are capable of emitting red light or infrared light of a second wavelength, wherein the first wavelength is different from the second wavelength, wherein the number of the first light emitting units and the number of the second light emitting units are the same, and wherein the plurality of first light emitting units and the plurality of second light emitting units are arranged into a row and column light source array; The optical receiving device includes a plurality of optical receivers respectively arranged at a plurality of different positions outside the abdomen of a pregnant woman, and a primary signal processor connected to the plurality of optical receivers. The primary signal processor includes an interface for receiving a fetal heart rate signal, which is used to be connected to a fetal heart rate acquisition device. The primary signal processor receives a plurality of optical signals related to fetal blood oxygen saturation through the plurality of optical receivers, and obtains the fetal heart rate signal collected simultaneously through the fetal heart rate acquisition device. The primary signal processor performs correlation analysis on the received plurality of optical signals related to fetal blood oxygen saturation and the fetal heart rate signal respectively to obtain the correlation coefficient of each optical signal; obtains the weighting coefficient corresponding to each optical signal based on the correlation coefficient; and superimposes the plurality of optical signals according to their respective weighting coefficients to obtain the sum of the optical signals.

2. The fetal blood oxygen optical signal acquisition device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device according to claim 1 is characterized in that: The multiple light receivers of the light receiving device are arranged around the light source of the light emitting light source device to form a circle.

3. The fetal blood oxygen optical signal acquisition device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device according to claim 1 is characterized in that: Multiple first light-emitting units arranged at equal or unequal intervals constitute an m*n first row and column light source array, and multiple second light-emitting units arranged at equal or unequal intervals constitute an m*n second row and column light source array, where n is an integer greater than 1 and m is an integer greater than or equal to 1.

4. The fetal blood oxygen optical signal acquisition device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device according to claim 1, characterized in that: A plurality of first light-emitting units and a plurality of second light-emitting units are arranged at equal or unequal intervals to form a row-column light source array of m rows and 2*n columns, each column of the row-column light source array is a first light-emitting unit column composed of first light-emitting units or a second light-emitting unit column composed of second light-emitting units, the first light-emitting unit columns and the second light-emitting unit columns are alternately arranged, n is an integer greater than 1, and m is an integer greater than or equal to 1; Alternatively, a plurality of first light-emitting units and a plurality of second light-emitting units are arranged at equal or unequal intervals to form a 2*m-row n-column row-column light source array, each row of the row-column light source array is a first light-emitting unit row composed of first light-emitting units or a second light-emitting unit row composed of second light-emitting units, the first light-emitting unit rows and the second light-emitting unit rows are alternately arranged, n is an integer greater than 1 and equal to, and m is an integer greater than 1.

5. The fetal blood oxygen optical signal acquisition device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device according to claim 1, characterized in that: In a row-column light source array composed of a plurality of first light-emitting units and a plurality of second light-emitting units, the first light-emitting units and the second light-emitting units are alternately arranged, so that the first light-emitting units and the second light-emitting units in each row of the row-column light source array are alternately arranged and the first light-emitting units and the second light-emitting units in each column of the row-column light source array are also alternately arranged.

6. The fetal blood oxygen optical signal acquisition device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device according to claim 1, characterized in that: A light diffusion lens for diffusing the irradiation area is provided outside the light source array formed by the plurality of first light emitting units and the plurality of second light emitting units of the light emitting light source.

7. The fetal blood oxygen optical signal acquisition device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device according to claim 6, characterized in that: The light diffusion lens is a concave lens, and the distance between the concave lens and the first light-emitting unit and the second light-emitting unit is greater than 0; or, the light diffusion lens is a convex lens, and the distance between the convex lens and the first light-emitting unit and the second light-emitting unit is greater than 0 and less than or equal to the focal length of the convex lens.

8. The fetal blood oxygen optical signal acquisition device of the extra-abdominal non-invasive fetal blood oxygen saturation detection device according to claim 1, characterized in that: The light source device comprises at least two first light emitting units and at least two second light emitting units.

Images