Solid phase microextraction sampling device and system

Abstract

The present invention provides a solid phase microextraction sampling device and a system thereof, and relates to the technical field of solid phase microextraction instruments. A solid phase microextraction sampling device comprises a bracket and a magnetic stirring device. The bracket comprises a fixing part and a fixing tube, the fixing tube is provided with a plurality of through holes, the aperture of the through holes gradually increases or decreases, and the handle of the solid phase microextraction instrument is fixed to the fixing tube through the through holes. This structure enables the fixing tube to fix the handle of the solid phase microextraction instrument only by setting through holes of different aperture sizes, which is quick and easy to use, and effectively reduces the production cost. Multiple samples can be extracted simultaneously, which is efficient and convenient, and reduces the influence of the environment and time on the samples. The magnetic stirring device comprises a water bath, and the water bath is provided with a fixing net. The fixing net is composed of a plurality of spring steel wires. By adjusting the spacing between two adjacent spring steel wires, it is suitable for sample bottles of different specifications. Extraction of samples of different specifications is achieved.

Description

Technical Field

[0001] The invention relates to the technical field of solid phase microextraction instruments, and in particular to a solid phase microextraction sampling device and a system thereof. Background Art

[0002] Sample pretreatment is a crucial link in the analytical chemistry process, which occupies more than 60% of the entire analytical process. The main analytical errors also come from the sample pretreatment link. The advancement of the sample pretreatment process is directly related to the quality of the analytical method. Its progress has a significant impact on the development of analytical chemistry. The exploration and research of various new technologies and methods for sample pretreatment has become one of the main development directions of contemporary analytical chemistry. Fast, simple and automated pretreatment technology not only saves time and effort, but also reduces the errors caused by different personnel operations and multiple sample transfers. It can also avoid the use of large amounts of organic solvents and reduce environmental pollution. In-depth research on sample pretreatment technology will surely play a positive role in promoting the development of analytical chemistry.

[0003] Solid phase microextraction (SPME) is a new sample pretreatment technology developed on the basis of solid phase extraction technology, which integrates sampling, extraction, concentration and injection. It can be used in conjunction with instruments such as gas chromatography or gas chromatography-mass spectrometry. It has a series of advantages such as simplicity, rapidity, high sensitivity, low cost and small amount of sample required. Therefore, it has always been highly concerned by analytical chemists and is widely used in the field of chromatography technology. At present, the SPME devices widely used at home and abroad are mainly produced by Supelco in the United States. Although the company is equipped with various extraction heads, automatic and manual handles, sampling tables, etc., its operating platform still cannot meet the requirements of simultaneous pretreatment of multiple samples, and also limits the volume of samples, which directly affects the accuracy and application scope of SPME pretreatment technology. In this context, the development of a set of SPME sampling table devices suitable for samples of different specifications and multiple samples that can be processed simultaneously is of great significance to improve the efficiency of analysis and the accuracy of analysis results. Summary of the invention

[0004] The object of the present invention is to provide a solid phase microextraction sampling device with a simple structure, suitable for samples of different volumes, capable of processing multiple samples simultaneously, and efficient and convenient.

[0005] Another object of the present invention is to provide a solid phase microextraction sampling system that is suitable for samples of different volumes, can process multiple samples simultaneously, is efficient and convenient, and reduces the impact of the environment and time on the samples.

[0006] The embodiment of the present invention is achieved as follows:

[0007] A solid phase microextraction sampling device comprises a bracket and a magnetic stirring device, wherein the bracket is fixedly connected to the magnetic stirring device.

[0008] The bracket comprises a fixing piece and a fixing tube. The fixing piece is selectively fixedly connected with the bracket along the length direction of the bracket, and the fixing tube is detachably connected with the fixing piece.

[0009] The fixed tube is provided with a plurality of through holes, the apertures of which gradually increase or decrease, and are used to fix the handle of the solid phase extractor.

[0010] Furthermore, in a preferred embodiment of the present invention, the fixing tube is an L-shaped structure, and the bent portion of the fixing tube is connected to the fixing piece.

[0011] Furthermore, in a preferred embodiment of the present invention, the bracket is provided with a scale along its length direction.

[0012] Furthermore, in a preferred embodiment of the present invention, the central axis of the through hole is perpendicular to the horizontal plane.

[0013] Furthermore, in a preferred embodiment of the present invention, the aperture of the through hole gradually decreases from the top end to the bottom end.

[0014] Furthermore, in a preferred embodiment of the present invention, the magnetic stirring device includes a water bath and a control system, and the control system is electrically connected to the water bath for controlling the water bath.

[0015] Furthermore, in a preferred embodiment of the present invention, the water bath is provided with a fixed net, and the fixed net is arranged on the top of the water bath.

[0016] The fixed net is composed of a plurality of spring steel wires, and both ends of each spring steel wire are detachably connected to the water bath pot.

[0017] Furthermore, in a preferred embodiment of the present invention, the control system includes a speed adjustment button, a timing reminder button, an ultrasonic switch button, a timing control button and a heating control button, and the speed adjustment button, the timing reminder button, the ultrasonic switch button, the timing control button and the heating control button are all arranged in the water bath.

[0018] Furthermore, in a preferred embodiment of the present invention, a thermocouple, an ultrasonic probe and a motor are provided inside the water bath, the thermocouple is connected to the heating control button, the ultrasonic probe is respectively connected to the timing reminder button, the ultrasonic switch button and the timing control button, and the motor is respectively connected to the speed adjustment button, the timing reminder button and the timing control button.

[0019] A solid phase microextraction sampling system comprises a power supply device and the solid phase microextraction sampling device, wherein the power supply device is electrically connected to the solid phase microextraction sampling device.

[0020] Beneficial effects of the embodiments of the present invention:

[0021] The present invention provides a solid phase microextraction sampling device, comprising a bracket and a magnetic stirring device. The bracket is fixedly connected to the magnetic stirring device. The bracket comprises a fixing member and a fixing tube, the fixing member is selectively fixedly connected to the bracket along the length direction of the bracket, and the fixing tube is detachably connected to the fixing member. The fixing tube is provided with a plurality of through holes, the apertures of which gradually increase or decrease, and are used to fix the handle of the solid phase microextraction instrument. This structure enables the fixing tube to fix the handle of the solid phase microextraction instrument by only providing through holes of different aperture sizes, which is quick and easy to use, and effectively reduces the production cost.

[0022] Furthermore, the magnetic stirring device includes a water bath, and the water bath is provided with a fixed net. The fixed net is composed of a plurality of spring steel wires, and both ends of each spring steel wire are detachably connected to the water bath. The fixed net fixes the sample bottle in a buckle-type connection. This structure and connection method make the assembly, disassembly and replacement of the spring steel wire extremely convenient, and the distance between two adjacent spring steel wires can be adjusted arbitrarily, so that it is suitable for sample bottles of different specifications. The solid phase microextraction sampling device can realize the simultaneous extraction of samples of different specifications and multiple samples, which is efficient and convenient, and reduces the influence of the environment and time on the samples. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0024] Figure 1 A schematic diagram of the structure of a solid phase microextraction sampling device provided in an embodiment of the present invention;

[0025] Figure 2 A schematic diagram of the structure of a bracket and a solid phase microextraction instrument handle provided in an embodiment of the present invention;

[0026] Figure 3 A schematic diagram of the structure of a magnetic stirring device provided in an embodiment of the present invention;

[0027] Figure 4 A schematic structural diagram of a spring steel wire provided in an embodiment of the present invention.

[0028] Icons: 100-solid phase microextraction sampling device; 110-bracket; 111-fixing part; 112-clamp; 113-fixing tube; 120-solid phase microextraction instrument handle; 121-through hole; 130-magnetic stirring device; 131-water bath; 133-fixing net; 135-spring steel wire; 140-control system; 141-speed adjustment button; 143-timing reminder button; 145-ultrasonic switch button; 147-timing control button; 149-heating control button. DETAILED DESCRIPTION

[0029] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, rather than all of the embodiments. The components of the embodiments of the present invention generally described and shown in the drawings here can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the present invention. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0030] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0031] In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc. indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, or are the directions or positional relationships in which the inventive product is usually placed when in use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore should not be understood as a limitation on the present invention.

[0032] Furthermore, the terms “first”, “second”, “third”, etc. are merely used for distinguishing descriptions and are not to be understood as indicating or implying relative importance.

[0033] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0034] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0035] Some embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the present invention, all embodiments, implementations and features of the present invention can be combined with each other without contradiction or conflict. In the present invention, conventional equipment, devices, components, etc. can be purchased commercially or made according to the contents disclosed in the present invention. In the present invention, in order to highlight the key points of the present invention, some conventional operations and equipment, devices, and components are omitted or only briefly described.

[0036] Example

[0037] Please refer to Figure 1 and Figure 2 , this embodiment provides a solid phase microextraction sampling device 100, including a bracket 110 and a magnetic stirring device 130, and the bracket 110 is used to fix the solid phase microextraction instrument handle 120. The bracket 110 is fixedly connected to the magnetic stirring device 130, and the solid phase microextraction instrument handle 120 is arranged on the bracket 110. In this embodiment, the bracket 110 is perpendicular to the magnetic stirring device 130, that is, the bracket 110 is perpendicular to the placement surface of the solid phase microextraction sampling device 100. The bracket 110 in this embodiment is a cylindrical structure, and the bracket 110 is made of iron material. In other embodiments of the present invention, the bracket 110 can be a prismatic structure, and its material can be other materials such as aluminum alloy, which is not limited by the present invention.

[0038] The bracket 110 includes a fixing member 111 and a fixing tube 113. The fixing member 111 is selectively fixedly connected to the bracket 110 along the length direction of the bracket 110, and the fixing tube 113 is detachably connected to the fixing member 111. In the present embodiment, the fixing member 111 is a fixing screw knob, and the fixing screw knob includes relatively arranged clamping plates 112. The fixing tube 113 is placed between the two clamping plates 112, and the fixing tube 113 is fixed to the bracket 110 by screwing the screw knob. There are two fixing screw knobs, which are relatively arranged on both sides of the bracket 110. The fixing member 111 can move relative to the bracket 110 according to the required height and be fixed to the bracket 110 at a certain height. For accurate height, the bracket 110 is provided with a scale along its length direction. It should be noted that the connection method of the fixing member 111 and the bracket 110 can be a sliding connection or other common methods in the technical field, which are not limited by the present invention.

[0039] In this embodiment, the fixed tube 113 is an L-shaped structure, and the bent portion of the fixed tube 113 is connected to the fixing member 111. This structure can expand the range of action of the fixed tube 113, increase the number of samples extracted simultaneously, and improve efficiency. In other embodiments of the present invention, the fixed tube 113 can be a W-shaped structure or other shapes, which are not limited by the present invention.

[0040] The solid phase microextraction instrument handle 120 is fixed to the fixed tube 113. Specifically, the fixed tube 113 is provided with a plurality of through holes 121, and the solid phase microextraction instrument handle 120 is fixed to the fixed tube 113 through the through holes 121. In order to improve the stability of the solid phase microextraction instrument handle 120, the aperture of the through hole 121 gradually increases or decreases. In the present embodiment, the aperture of the through hole 121 gradually decreases from the top to the bottom. And the aperture of the top of the through hole 121 is slightly larger than the diameter of the solid phase microextraction instrument handle 120, and the aperture of the bottom of the through hole 121 is smaller than the diameter of the solid phase microextraction instrument handle 120. It should be noted that the central axis of the through hole 121 is perpendicular to the horizontal plane. This structure makes the solid phase microextraction instrument handle 120 perpendicular to the horizontal plane. In the present embodiment, the multiple through holes 121 on the fixed tube 113 are arranged at equal intervals, and the number of through holes 121 is adjusted as needed.

[0041] Please refer to Figure 3 The magnetic stirring device 130 includes a water bath 131 and a control system 140 . The control system 140 is electrically connected to the water bath 131 and is used to control parameters such as the temperature and ultrasonic conditions of the water bath 131 .

[0042] In order to ensure the stability of the sample and the quality of the extraction, the water bath 131 is provided with a fixed net 133 for fixing the sample bottle. In this embodiment, the fixed net 133 is arranged on the top of the water bath 131. The fixed net 133 is connected to the water bath 131 in a buckle-type connection. Specifically, the fixed net 133 is composed of a plurality of spring steel wires 135 crisscrossed, such as Figure 4 The two ends of each spring steel wire 135 are bent and detachably connected to the water bath 131. The distance between the spring steel wires 135 can be adjusted according to the size of the fixed sample bottle, and then the mesh size of the fixed net 133 can be adjusted to make it suitable for sample bottles of different specifications, which is convenient to use.

[0043] The control system 140 includes a speed adjustment button 141, a timer reminder button 143, an ultrasonic switch button 145, a timing control button 147, and a heating control button 149. The speed adjustment button 141, the timer reminder button 143, the ultrasonic switch button 145, and the timing control button 147 are arranged in the water bath 131. A thermocouple (not shown), an ultrasonic probe (not shown), and a motor (not shown) are arranged inside the water bath 131. The thermocouple is connected to the heating control button 149, the ultrasonic probe is respectively connected to the timing reminder button 143, the ultrasonic switch button 145, and the timing control button 147, and the motor is respectively connected to the speed adjustment button 141, the timing reminder button 143, and the timing control button 147.

[0044] This embodiment also provides a solid phase microextraction sampling system (not shown) based on the solid phase microextraction sampling device 100, including a power supply device (not shown) and the solid phase microextraction sampling device 100, wherein the power supply device is used to provide electrical energy to the solid phase microextraction sampling device 100.

[0045] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A solid phase microextraction sampling device, characterized in that: It comprises a bracket and a magnetic stirring device, wherein the bracket is fixedly connected to the magnetic stirring device. The bracket comprises a fixing member and a fixing tube, wherein the fixing member is selectively fixedly connected to the bracket along the length direction of the bracket, and the fixing tube is detachably connected to the fixing member; The fixing tube is provided with a plurality of through holes, the apertures of which gradually increase or decrease, and are used to fix the handle of the solid phase extractor; The fixing tube is an L-shaped structure, and the bent portion of the fixing tube is connected to the fixing member; The magnetic stirring device comprises a water bath and a control system, wherein the control system is electrically connected to the water bath and is used to control the water bath; The water bath is provided with a fixed net, and the fixed net is arranged on the top of the water bath; The fixed net is composed of a plurality of spring steel wires, and both ends of each of the spring steel wires are detachably connected to the water bath, so that the distance between the spring steel wires can be adjusted according to the size of the fixed sample bottle, thereby adjusting the mesh size of the fixed net so that the fixed net can be suitable for the sample bottles of different specifications.

2. The solid phase microextraction sampling device according to claim 1, characterized in that: The bracket is provided with a scale along the length direction thereof.

3. The solid phase microextraction sampling device according to claim 1, characterized in that: The central axis of the through hole is perpendicular to the horizontal plane.

4. The solid phase microextraction sampling device according to claim 3, characterized in that: The aperture of the through hole gradually decreases from the top end to the bottom end.

5. The solid phase microextraction sampling device according to claim 1, characterized in that: The control system includes a speed adjustment button, a timing reminder button, an ultrasonic switch button, a timing control button and a heating control button, and the speed adjustment button, the timing reminder button, the ultrasonic switch button, the timing control button and the heating control button are all arranged on the water bath.

6. The solid phase microextraction sampling device according to claim 5, characterized in that: A thermocouple, an ultrasonic probe and a motor are provided inside the water bath, the thermocouple is connected to the heating control button, the ultrasonic probe is respectively connected to the timing reminder button, the ultrasonic switch button and the timing control button, and the motor is respectively connected to the speed adjustment button, the timing reminder button and the timing control button.

7. A solid phase microextraction sampling system, characterized in that: It comprises a power supply device and the solid phase microextraction sampling device according to any one of claims 1 to 6, wherein the power supply device is electrically connected to the solid phase microextraction sampling device.

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