Automatic membrane passing device for organic solution

Abstract

The present invention relates to an automatic membrane-passing device for organic solutions, comprising a carrier and a stepped guide rail located inside the carrier, wherein a pullable automatic lifting chromatographic bottle carrier is arranged inside the carrier, wherein the carrier comprises a base and a side plate located at the end of the base, wherein the base has support columns on both sides along the length direction, and the top of the support columns is a top plate; the top plate has neatly arranged holes for inserting and fixing a disposable sealing column. The manual filtering process of the experimenter is converted into a machine-automated filtering process, which overcomes the shortcomings of the manual filtering process, such as complicated operation, slow efficiency, and the toxicity of the solvent to the human body, and can effectively improve the work efficiency of the experimenter and keep the experimenter away from the toxicity of organic reagents.

Description

Technical Field

[0001] The invention relates to the field of organic matter processing devices, in particular to an automatic membrane passing device for organic solutions. Background Art

[0002] In the current laboratory, liquid chromatography, gas chromatography, liquid chromatography-mass spectrometry, and gas chromatography-mass spectrometry are used to measure organic substances, which require a large amount of pre-treatment work on the organic substances, generally requiring complex processes such as weighing, crushing, extraction, centrifugation, and filter membranes. The existing technology has a large number of instruments that have replaced the manual experimental methods in terms of weighing, crushing, extraction, and centrifugation. However, before the last step of transferring the sample to the detection instrument on the chromatographic bottle, all impurities in the organic solution are removed by artificial membrane. Most laboratories now purchase disposable syringes and filter heads to manually extract organic reagents and pass through disposable filter membranes to transfer organic solutions into liquid chromatography bottles. The manual operation of this process is complex, the efficiency is slow, and the solvent is toxic to the human body. The amount of organic samples in the laboratory is very large every day, which causes the experimenters to waste a lot of time during the filtration process. Summary of the invention

[0003] The technical problem to be solved by the present invention is to provide an automatic membrane passing device for organic solutions to solve the defects existing in the prior art.

[0004] The technical solution of the present invention to solve the above technical problems is as follows:

[0005] An automatic membrane-passing device for organic solutions, comprising a carrier and a stepped guide rail located inside the carrier, a pullable automatic lifting chromatographic bottle carrier is arranged inside the carrier, the carrier comprises a base and a side plate located at the end of the base, the base has support columns on both sides along the length direction, and the top of the support columns is a top plate; the top plate has neatly arranged holes for inserting and fixing disposable sealing columns, the opposite side of the side plate is an opening, the inner side surface of the side plate is provided with a second magnet, and the end of the automatic lifting chromatographic bottle carrier is provided with a first magnet that cooperates with the second magnet;

[0006] Furthermore, the upper portion of the disposable sealing column is fixedly connected to a chromatographic bottle cap, and the lower portion is fixedly connected to a chromatographic filter head;

[0007] Furthermore, the automatic lifting chromatographic bottle carrier comprises a base frame and a chromatographic bottle position above the base frame, the base frame and the chromatographic bottle position are staggered, and the base frame and the chromatographic bottle position are connected by a slider and a tension spring; both sides of the base frame are provided with internal guide rails;

[0008] The beneficial effects of the present invention are: converting the manual filtration process of the experimenter into a machine-automated filtration process, overcoming the shortcomings of the manual filtration process, such as complex operation, low efficiency, and solvent toxicity to the human body, which can effectively improve the work efficiency of the experimenter and keep the experimenter away from the toxicity of organic reagents. BRIEF DESCRIPTION OF THE DRAWINGS

[0009] Figure 1 It is a schematic diagram of the structure of the present invention;

[0010] Figure 2 This is a schematic diagram of the cross-sectional structure of the automatic lifting chromatographic bottle rack of the present invention;

[0011] Figure 3 This is a schematic diagram of the structure of the automatic lifting chromatographic bottle rack of the present invention;

[0012] Figure 4 This is a schematic diagram of the installation structure of the disposable sealing column of the present invention;

[0013] Figure 5 It is a schematic diagram of the carrier structure of the present invention;

[0014] The attached markings are as follows:

[0015] 1. Chromatographic bottle cap, 2. Disposable sealing column, 3. Carrier, 4. Chromatographic filter head, 5. Chromatographic bottle, 6. Automatic lifting chromatographic bottle carrier, 61. Base frame, 62. Slider, 63. Tension spring, 64. Chromatographic bottle position, 65. Magnet 1, 66. Handle, 67. Internal guide rail, 7. Magnet 2, 8. Stepped guide rail, 9. Base, 10. Side plate, 11. Support column, 12. Top plate; DETAILED DESCRIPTION

[0016] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.

[0017] like Figure 1 As shown, an automatic membrane-passing device for organic solutions comprises a carrier 3 and a stepped guide rail 8 located inside the carrier 3, a retractable automatic lifting chromatographic bottle carrier 6 is arranged inside the carrier 3, the carrier 3 comprises a base 9 and a side plate 10 located at the end of the base 9, the base 9 has support columns 11 on both sides along the length direction, and the top of the support column 11 is a top plate 12; the top plate 12 has neatly arranged holes for inserting and fixing a disposable sealing column 2, the opposite side of the side plate 10 is an opening, the inner side surface of the side plate 10 is provided with a second magnet 7, and the end of the automatic lifting chromatographic bottle carrier 6 is provided with a first magnet 65 that cooperates with the second magnet 7;

[0018] More specifically, the upper portion of the disposable sealing column 2 is fixedly connected to a chromatographic bottle cap 1, and the lower portion is fixedly connected to a chromatographic filter head 4;

[0019] More specifically, the automatic lifting chromatographic bottle carrier 6 includes a bottom frame 61 and a chromatographic bottle position 64 above the bottom frame 61, the bottom frame 61 and the chromatographic bottle position 64 are staggered, and the bottom frame 61 and the chromatographic bottle position 64 are connected by a slider 62 and a tension spring 63; both sides of the bottom frame 61 have internal guide rails 67;

[0020] The invention is an automated organic solvent filtration device, which mainly consists of 6 parts:

[0021] 1. Chromatographic bottle cap: This cap is a statistical standard chromatographic bottle cap on the market (without pre-cut). This bottle cap has a sealing function in the system and provides a certain positive pressure for the membrane.

[0022] 2. Disposable sealing column: This part is an independently designed part, which is completely matched with the membrane system. This part can effectively connect the chromatographic bottle cap and the chromatographic filter head below.

[0023] 3. Chromatographic filter head: This part is the standard filter head on the market. Its main function is to filter and remove impurities in organic solutions.

[0024] The three parts above can be combined into a whole: the upper chromatographic bottle cap and the lower chromatographic filter head are connected into a whole through an independently designed disposable sealing column, thus forming a sealed device. The device can automatically complete the filtration process through a fully automatic multifunctional liquid handling workstation. The automated liquid handling workstation has the characteristics of accurate positioning, and is equipped with a puncture steel needle and a liquid adding device, thereby realizing the automated filtration process of organic solutions.

[0025] 4. Chromatographic bottle: This part is a 2ml chromatographic bottle commonly seen on the market, which has the function of receiving the organic solution after filtering from the upper part.

[0026] 5. Automatic lifting chromatographic bottle rack: This part is an independently designed part, which can seal the upper chromatographic filter head with the chromatographic bottle. This part adopts a push-pull automatic lifting design. After the combination of the three parts of the disposable sealing column is placed on the carrier, the chromatographic bottle is placed in the automatic lifting chromatographic bottle carrier, and the chromatographic bottle carrier is pushed into the carrier as a whole. When a part of the carrier is pushed in, the chromatographic carrier will automatically rise, so that the chromatographic bottle and the upper chromatographic filter head are tightly fitted together, effectively avoiding the volatilization of organic solvents in the chromatographic bottle during the filtration process.

[0027] The principle of automatic lifting of the chromatographic bottle rack: the chromatographic bottle rack is divided into two parts. Before being placed in the carrier, the two parts will be separated by the tension spring and the guide rail. In the process of placing it in the carrier, the chromatographic bottle rack is pushed into the carrier. The carrier has a stepped guide rail at the fixed position of the chromatographic bottle rack. When the chromatographic bottle rack is pushed into the stepped guide rail, the upper part of the chromatographic bottle rack will first reach the bottom of the carrier. At this time, the lower part of the chromatographic bottle rack continues to be pushed in, the tension spring is stretched, and the chromatographic bottle rack automatically rises through the stepped guide rail. The upper and lower parts of the chromatographic bottle rack overlap, and the rise is completed. The chromatographic bottle rack uses its magnet to adsorb the chromatographic bottle rack on the carrier to complete the automatic rising process of the chromatographic bottle rack; when taking down the chromatographic bottle rack: just pull out the chromatographic bottle rack, the tension spring will separate the upper and lower parts, and it will automatically descend through the stepped guide rail and return to its original state.

[0028] 6. Carrier: The carrier is an independently designed product: the upper parts can be integrated together and can be installed in a fully automatic multi-functional liquid handling workstation to realize the automated filtration process of the entire organic solution.

[0029] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. An automatic membrane-passing device for organic solutions, characterized in that: The invention comprises a carrier and a stepped guide rail located inside the carrier, the carrier comprises a base and a side plate located at the end of the base, a pullable automatic lifting chromatographic bottle carrier is arranged inside the carrier, the base has support columns on both sides along the length direction, and the top of the support columns is a top plate; the top plate has neatly arranged holes for inserting and fixing disposable sealing columns, the opposite side of the side plate is an opening, the inner side surface of the side plate is provided with a second magnet, the end of the automatic lifting chromatographic bottle carrier is provided with a first magnet matched with the second magnet, the automatic lifting chromatographic bottle carrier comprises a bottom frame and a chromatographic bottle position above the bottom frame, the bottom frame and the chromatographic bottle position are staggered, and the bottom frame and the chromatographic bottle position are connected by a slider and a tension spring; the bottom frame has internal guide rails on both sides.

2. The automatic membrane-passing device for organic solution according to claim 1, characterized in that: The upper part of the disposable sealing column is fixedly connected with a chromatographic bottle cap, and the lower part is fixedly connected with a chromatographic filter head.

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