Channel expandable blood testing device

By adopting a combined structure of three liquid adding tubes and a liquid draining base in the blood testing device, the problems of disassembly and assembly of reaction cups and function expansion are solved, allowing multiple types of testing to be performed simultaneously, improving the flexibility and efficiency of testing.

CN111157715BActive Publication Date: 2025-01-17NINGBO MEDICALSYSTEM SHENGDA BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202010074024.7
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2020-01-22
Publication Date
2025-01-17
Estimated Expiration
2040-01-22

AI Technical Summary

Technical Problem

The existing blood detection devices have difficulties in replacing the reaction cup and expanding the function, which is inconvenient to disassemble and assemble, and the single-channel design limits the simultaneous operation of multiple types of detection.

Method used

A channel-expandable blood detection device is designed. It adopts a combined structure of three liquid adding tubes and a drain base to make the disassembly and assembly of the reaction cup simple. By adding detection channels and corresponding laser module light sources and reagent types, a variety of Type detection is performed simultaneously.

Benefits of technology

It achieves simple disassembly and assembly of reaction cups and easy expansion of functions, and can conduct multiple types of blood tests at the same time, improving the flexibility and efficiency of testing.

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Abstract

The present invention relates to the technical field of blood testing instruments, and provides a channel-expandable blood testing device, comprising a laser module, a receiving component, a reagent cavity and at least one detection channel, wherein the detection channel comprises a reaction cup, three liquid-adding tubes, a liquid-discharging base and a base, wherein the reaction cup is fixed on the base; the three liquid-adding tubes are arranged above the reaction cup and facing the cup mouth of the reaction cup, and are used to add reagents to the reaction cup; the liquid-discharging base is arranged below the reaction cup and corresponds to the liquid-discharging port of the reaction cup, and is used to discharge the liquid in the reaction cup into other components; the number of light sources of the laser module and the number of types of reagents stored in the reagent cavity are both corresponding to the number of detection channels; the reagent cavity provides reagents to the three liquid-adding tubes; the laser module emits laser light to a sample in the reaction cup, and the laser light is received by the receiving component after being scattered by the sample.
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Description

Technical Field

[0001] The present invention relates to the technical field of blood testing instruments, and more specifically to a blood testing device with expandable channels. Background Art

[0002] In the blood testing devices currently on the market, a single reaction cup serving as a reaction chamber for blood samples and reagents is connected to a plurality of hoses and fixed to a base by screws, such as Figure 5 As shown, to replace the reaction cup, the hose and screws must be removed, which is very inconvenient. Moreover, most of the current blood testing devices are single-channel, for example, they can only perform SAA testing or CRP testing. It is particularly difficult to expand the functions of the reaction cup using the existing assembly method. CRP, the full name of C-reactive protein, is an acute phase protein synthesized by liver cells; SAA, the full name of serum amyloid A, is an acute phase protein produced by liver cells and secreted into the serum. Summary of the invention

[0003] The technical problem to be solved by the present invention is to provide a channel-expandable blood testing device, which adopts a new assembly method for the reaction cup serving as the blood sample and reagent reaction chamber, is simple to assemble and disassemble, convenient to replace, and easy to expand functions. After the channel expansion, multiple types of tests can be performed on the blood sample at the same time, such as CRP testing and SAA testing at the same time.

[0004] The technical solution of the present invention is to provide a channel-expandable blood detection device, including a laser module, a receiving component, a reagent cavity and at least one detection channel, wherein the detection channel includes a reaction cup, three liquid-adding tubes, a liquid-discharging base and a base, wherein the reaction cup is fixed on the base; the three liquid-adding tubes are arranged above the reaction cup and facing the cup mouth of the reaction cup, and are used to add reagents to the reaction cup; the liquid-discharging base is arranged below the reaction cup and corresponds to the liquid-discharging port of the reaction cup, and is used to discharge the liquid in the reaction cup into other components; the number of light sources of the laser module and the number of types of reagents stored in the reagent cavity both correspond to the number of detection channels; the reagent cavity provides reagents to the three liquid-adding tubes; the laser module emits laser light to the sample in the reaction cup, and the laser light is received by the receiving component after being scattered by the sample.

[0005] Compared with the prior art, the channel-expandable blood testing device of the present invention has the following advantages: the three liquid-adding tubes are arranged above the reaction cup for adding reagents to the reaction cup, the liquid-discharging base is arranged below the reaction cup for discharging the liquid in the reaction cup to other components, and the three liquid-adding tubes and the liquid-discharging base are not directly connected to the reaction cup, so that the reaction cup is easy to disassemble and assemble; the blood testing device of the present invention is easy to expand its functions, and multiple types of tests can be performed on blood samples at the same time by simply increasing the number of detection channels and the corresponding number of light sources of the laser module and the number of types of reagents stored in the reagent chamber.

[0006] Preferably, the reaction cup is in the shape of a funnel with a cup opening size larger than the size of the lower bottom surface, at least one locking protrusion is provided on the outer side wall of the lower part of the reaction cup, and the base is provided with a mounting hole corresponding to the shape of the reaction cup and a slideway matched with the locking protrusion. After the reaction cup enters the mounting hole and rotates at any angle, the outer side wall of the reaction cup conflicts with the side wall of the mounting hole, and the locking protrusion conflicts with the lower bottom surface of the base, so that the reaction cup is fixed on the base. With this structure, the reaction cup can be installed, fixed or removed by simply rotating the reaction cup by a certain angle, which is simple to operate and does not require disassembly of pipelines.

[0007] Preferably, the drainage base is fixed on the bottom surface of the base, the drainage base is fixed on the lower bottom surface of the base, and a drainage nozzle corresponding to the drainage port of the reaction cup is provided on the drainage base, and when the reaction cup is fixed on the base, the drainage port of the reaction cup is connected with the drainage nozzle. With this structure, after the reaction cup is installed on the base, the drainage port of the reaction cup is directly connected with the drainage nozzle on the drainage base, and no pipeline needs to be installed separately.

[0008] Preferably, the detection channel further includes a sealing gasket, a groove corresponding to the lower bottom surface of the reaction cup is provided on the liquid discharge base, the sealing gasket is provided in the groove and a through hole corresponding to the liquid discharge nozzle is provided on the sealing gasket, when the reaction cup is fixed on the base, the lower bottom surface of the reaction cup is pressed against the sealing gasket, and the liquid discharge port of the reaction cup is connected to the liquid discharge nozzle through the through hole on the sealing gasket. With this structure, the bottom surface of the reaction cup presses the sealing gasket, so that the sealing performance of the reaction cup is reliable, the assembly is simple, and there is no need to disassemble the pipeline.

[0009] Preferably, the channel expandable blood testing device of the present invention further comprises a liquid adding three-tube rack, a carrying rack, and a buckle, wherein the liquid adding three-tube rack is mounted on the liquid adding three-tube rack, and the liquid adding three-tube rack is fixed to the carrying rack by the buckle. With this structure, the liquid adding three-tube rack can be located above the reaction cup and facing the cup mouth of the reaction cup by simple installation, and the liquid adding three-tube rack does not need to be directly connected to the reaction cup.

[0010] Preferably, the channel expandable blood testing device of the present invention further comprises a rear seat and a front seat, one end of the laser module is fixed on the rear seat, and the other end is fixed on the front seat, and the rear seat, the base, and the receiving component are arranged in sequence and located on the same optical path. With this structure, the position of the laser spot on the reaction cup can be adjusted by adjusting the position of the rear seat and the front seat.

[0011] Preferably, the channel expandable blood testing device of the present invention also includes a temperature control system composed of a heating rod, a temperature sensor, and a thermal protection component. The heating rod, the temperature sensor, and the thermal protection component are all installed in the base, and the reagent cavity is arranged on one side of the base. With this structure, the temperature control system can perform constant temperature control on the entire blood testing device. The base transfers heat into the reaction cup through heating by the electric heating rod, so that the reaction cup reaches the optimal incubation temperature; the reagent cavity is placed on one side of the base, and the base transfers heat into the reagent cavity to preheat the reagent in advance.

[0012] Preferably, the channel expandable blood testing device of the present invention also includes a heat preservation cover, which is sleeved on the base. The base, the reaction cup installed on the base, and the reagent cavity are completely located inside the heat preservation cover, and the heat preservation cover is provided with a through hole corresponding to the cup mouth of the reaction cup. With this structure, all parts involved in the sample reaction are in a constant temperature environment to avoid a large amount of heat loss. The three liquid adding tubes can add reagents to the reaction cup through the through hole above the heat preservation cover.

[0013] Preferably, there are two detection channels, the laser module includes a light source for detecting CRP and a light source for detecting SAA, and the reagent chamber stores reagents for detecting CRP and reagents for detecting SAA. With this structure, the present invention can be easily expanded into a dual-channel blood detection device capable of simultaneously performing CRP detection and SAA detection.

[0014] Preferably, the receiving component is a photocell. With this structure, the laser scattered light passing through the detection sample can be conveniently received and detected. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic assembly diagram of a dual-channel embodiment of the channel-expandable blood testing device of the present invention.

[0016] Figure 2 It is a schematic diagram of assembling a single-channel reaction cup in the channel-expandable blood testing device of the present invention.

[0017] Figure 3 It is a schematic diagram of assembling a dual-channel reaction cup in the channel-expandable blood testing device of the present invention.

[0018] Figure 4 This is a working diagram of a dual-channel embodiment of the channel-expandable blood testing device of the present invention.

[0019] Figure 5 The figure is a schematic diagram of assembling a single reaction cup in a blood testing device in the prior art.

[0020] As shown in the figure: 1. reaction cup, 1-1. positioning protrusion, 2. three-tube rack for adding liquid, 2-1. three tubes for adding liquid, 3. sealing gasket, 4. drainage base, 5. laser module, 6. heating rod, 7. temperature sensor, 8. receiving component, 9. insulation cover, 10. thermal protection component, 11. reagent cavity, 12. rear seat, 13. carrying frame, 14. buckle, 15. front seat, 16. three tubes for reagent injection, 17. drainage tube, 18. screw fixing seat, 19. reaction cup of prior art, 20. base. DETAILED DESCRIPTION

[0021] In order to better understand the present application, a more detailed description of various aspects of the present application will be made with reference to the accompanying drawings. It should be understood that these detailed descriptions are only descriptions of exemplary embodiments of the present application, and do not limit the scope of the present application in any way. Throughout the specification, the same figure numerals refer to the same elements.

[0022] In the drawings, the thickness, size and shape of objects have been slightly exaggerated for ease of explanation. The drawings are only examples and are not drawn strictly to scale.

[0023] It should also be understood that the terms "comprises", "having", "includes", "comprising", when used in this specification, indicate the presence of the described features, integers, steps, operations, elements and / or components, but do not exclude the presence or addition of one or more other features, integers, steps, operations, elements, components and / or combinations thereof. In addition, when a statement such as "...at least one" appears after a list of listed features, it modifies the entire listed features rather than modifying the individual elements in the list.

[0024] like Figure 2 As shown, when the blood testing device of the present invention is a single channel, there is only one reaction cup 1, and a single liquid adding three-tube 2-1 is installed on the liquid adding three-tube rack 2. The liquid adding three-tube 2-1 is arranged above the reaction cup 1 and directly facing the cup mouth of the reaction cup 1, and is used to add reagents to the reaction cup 1. A single groove corresponding to the lower bottom surface of the reaction cup 1 is arranged on the liquid discharge base 4, and a liquid discharge nozzle corresponding to the liquid discharge port of the reaction cup 1 is arranged in the groove. A sealing gasket 3 is also arranged in the groove. The lower bottom surface of the reaction cup 1 can be pressed against the sealing gasket 3, and the liquid discharge port of the reaction cup 1 is connected with the liquid discharge nozzle through the through hole on the sealing gasket 3, so that the liquid in the reaction cup 1 can be discharged to other components.

[0025] The blood testing device of the present invention is functionally expanded to form a dual-channel blood testing device, such as Figure 3As shown, there are two reaction cups 1, and two three-tube liquid adding tubes 2-1 are installed on the three-tube liquid adding rack 2. The three-tube liquid adding tube 2-1 is arranged above the reaction cup 1 and facing the cup mouth of the reaction cup 1, and is used to add reagents to the reaction cup 1. The drainage base 4 is provided with two grooves corresponding to the lower bottom surfaces of the two reaction cups 1 respectively, and drainage nozzles corresponding to the drainage ports of the reaction cups 1 are arranged in the grooves. A sealing gasket 3 is also arranged in the grooves. The lower bottom surface of the reaction cup 1 can be pressed against the sealing gasket 3, and the drainage port of the reaction cup 1 is connected with the drainage nozzle through the through hole on the sealing gasket 3, so that the liquid in the reaction cup 1 can be discharged to other components.

[0026] Figure 1It is a dual-channel embodiment of the channel expandable blood test device of the present invention, comprising a reaction cup 1, a three-tube rack 2 for adding liquid, a three-tube 2-1 for adding liquid, a sealing gasket 3, a liquid discharge base 4, a laser module 5, a heating rod 6, a temperature sensor 7, a receiving component 8, a heat preservation cover 9, a heat protection component 10, a reagent cavity 11, a rear seat 12, a mounting frame 13, a buckle 14, a front seat 15, and a base 20. The reaction cup 1 is in the shape of a funnel with a cup mouth size larger than a lower bottom surface size, two locking protrusions 1-1 are arranged on the outer side wall of the lower part of the reaction cup 1, and the base 20 is provided with a mounting hole corresponding to the shape of the reaction cup 1 and a slideway matched with the locking protrusion 1-1. After the reaction cup 1 enters the mounting hole, it rotates at any angle, so that the outer side wall of the reaction cup 1 conflicts with the side wall of the mounting hole, and the locking protrusion 1-1 conflicts with the lower bottom surface of the base 20, and then the reaction cup 1 is fixed on the base 20. The reaction cup can be installed, fixed or removed by rotating the reaction cup at a certain angle, which is simple to operate and does not require disassembly of pipelines. The three-tube liquid addition tube 2-1 is installed on the three-tube liquid addition rack 2, and the three-tube liquid addition rack 2 is fixed on the carrier rack 13 so that the three-tube liquid addition tube 2-1 is located above the reaction cup 1 and directly faces the cup mouth of the reaction cup 1, which is convenient for adding reagents to the reaction cup 1. The liquid discharge base 4 is used to discharge the liquid in the reaction cup 1 to other components. The liquid discharge base 4 is fixed on the lower bottom surface of the base 20, and the liquid discharge base 4 is provided with a groove corresponding to the lower bottom surface of the reaction cup 1, and a liquid discharge nozzle corresponding to the liquid discharge port of the reaction cup 1 is provided in the groove. The sealing gasket 3 is provided in the groove and a through hole is provided on the sealing gasket 3 corresponding to the liquid discharge nozzle. The reaction cup 1 is fixed on the base 20, and the lower bottom surface of the reaction cup 1 is pressed against the sealing gasket 3, and the liquid discharge port of the reaction cup 1 is connected to the liquid discharge nozzle through the through hole on the sealing gasket 3. The bottom surface of the reaction cup is pressed against the sealing gasket, so that the sealing performance of the reaction cup is reliable, the assembly is simple, and there is no need to disassemble the pipeline. One end of the laser module 5 is fixed on the rear seat 12, and the other end is fixed on the front seat 15. By adjusting the positions of the rear seat and the front seat, the position of the spot of the laser irradiated on the reaction cup can be adjusted. The rear seat 12, the base 20, and the receiving component 8 are arranged in sequence and located on the same optical path. The laser module 5 has 2 light sources, and 2 reagents can be stored in the reagent cavity 11. The reagent cavity 11 provides reagents to the liquid adding three tubes 2-1. The heating rod 6, the temperature sensor 7, and the thermal protection component 10 are all installed in the base 20, and the reagent cavity 11 is arranged between the base 20 and the rear seat 12. The heat preservation cover 9 is sleeved on the base 20, the base 20, the reaction cup 1 installed on the base 20, and is completely located inside the heat preservation cover 9. The heat preservation cover 9 is provided with a through hole corresponding to the cup mouth of the reaction cup 1 above. The whole blood testing device can be thermostatically controlled. The base transfers heat into the reaction cup through the electric heating rod, so that the reaction cup reaches the optimal incubation temperature. The reagent cavity 11 is placed on the rear side of the base. The base transfers heat into the reagent cavity to preheat the reagent. The receiving component 8 is a photocell.

[0027] The workflow of the channel-expandable blood testing device of the present invention is as follows: Figure 4 As shown, during normal testing, first add samples and reagents to the reaction cup, then make the laser module emit laser to the sample in the reaction cup, the laser is scattered by the sample and received by the receiving component to obtain the test result, the waste liquid after the reaction is discharged through the drain base, and the test is completed. If the reaction cup needs to be replaced, just open the buckle, remove the three liquid adding tubes, rotate the reaction cup a certain angle and remove it, then replace the new reaction cup and fix it, and then install the three liquid adding tubes, and the reaction cup replacement is complete.

[0028] The blood testing device of the present invention is also easy to expand in function. It only needs to increase the number of detection channels and the number of light sources of the laser module and the number of reagent types stored in the reagent chamber to simultaneously perform multiple types of tests on blood samples.

Claims

1. A blood testing device with expandable channels, characterized in that: The invention comprises a laser module (5), a receiving component (8), a reagent chamber (11) and at least one detection channel, wherein the detection channel comprises a reaction cup (1), a three-liquid adding tube (2-1), a liquid discharge base (4) and a base (20), wherein the reaction cup (1) is fixed on the base (20); the three-liquid adding tube (2-1) is arranged above the reaction cup (1) and directly facing the cup mouth of the reaction cup (1), and is used to add reagents to the reaction cup (1); the liquid discharge base (4) is arranged below the reaction cup (1) and corresponds to the liquid discharge port of the reaction cup (1), and is used to discharge liquid in the reaction cup (1) into other components; the number of light sources of the laser module (5) and the number of types of reagents stored in the reagent chamber (11) are both corresponding to the number of detection channels; the reagent chamber (11) provides reagents to the three-liquid adding tube (2-1); the laser module (5) emits laser light to the reaction cup (1); On the sample in the reaction cup (1), laser light is scattered by the sample and then received by the receiving component (8); the reaction cup (1) is in the shape of a funnel with a cup mouth size larger than the size of the lower bottom surface; at least one locking protrusion (1-1) is arranged on the outer wall of the lower part of the reaction cup (1); a mounting hole corresponding to the shape of the reaction cup (1) and a slideway matched with the locking protrusion (1-1) are arranged on the base (20); after the reaction cup (1) enters the mounting hole and rotates at any angle, the outer wall of the reaction cup (1) abuts against the side wall of the mounting hole, and the locking protrusion (1-1) abuts against the lower bottom surface of the base (20), so that the reaction cup (1) is fixed on the base (20); there are two detection channels, the laser module (5) comprises a light source for detecting CRP and a light source for detecting SAA, and the reagent chamber (11) stores a reagent for detecting CRP and a reagent for detecting SAA.

2. The channel expandable blood testing device according to claim 1, characterized in that: The liquid discharge base (4) is fixed on the lower bottom surface of the base (20), and a liquid discharge nozzle corresponding to the liquid discharge port of the reaction cup (1) is arranged on the liquid discharge base (4). When the reaction cup (1) is fixed on the base (20), the liquid discharge port of the reaction cup (1) is connected to the liquid discharge nozzle.

3. The channel expandable blood testing device according to claim 2, characterized in that: The detection channel also includes a sealing gasket (3). A groove corresponding to the lower bottom surface of the reaction cup (1) is provided on the liquid discharge base (4). The sealing gasket (3) is arranged in the groove and a through hole corresponding to the liquid discharge nozzle is provided on the sealing gasket (3). When the reaction cup (1) is fixed on the base (20), the lower bottom surface of the reaction cup (1) is pressed against the sealing gasket (3), and the liquid discharge port of the reaction cup (1) is connected to the liquid discharge nozzle through the through hole on the sealing gasket (3).

4. The channel expandable blood testing device according to claim 1, characterized in that: It also comprises a liquid adding three-tube rack (2), a carrying rack (13), and a buckle (14); the liquid adding three tubes (2-1) are installed on the liquid adding three-tube rack (2); and the liquid adding three-tube rack (2) is fixed on the carrying rack (13) by the buckle (14).

5. The channel expandable blood testing device according to claim 1, characterized in that: It also includes a rear seat (12) and a front seat (15), one end of the laser module (5) is fixed on the rear seat (12), and the other end is fixed on the front seat (15), and the rear seat (12), the base (20), and the receiving component (8) are arranged in sequence and located on the same optical path.

6. The channel expandable blood testing device according to claim 1, characterized in that: The device also includes a temperature control system consisting of a heating rod (6), a temperature sensor (7), and a thermal protection component (10). The heating rod (6), the temperature sensor (7), and the thermal protection component (10) are all installed in a base (20), and the reagent chamber (11) is arranged on one side of the base (20).

7. The channel expandable blood testing device according to claim 6, characterized in that: The invention also comprises a heat-insulating cover (9), which is sleeved on the base (20); the base (20), the reaction cup (1) mounted on the base (20), and the reagent chamber (11) are completely located inside the heat-insulating cover (9); and a through hole corresponding to the cup mouth of the reaction cup (1) is arranged above the heat-insulating cover (9).

8. The channel expandable blood testing device according to claim 1, characterized in that: The receiving component (8) is a photocell.

Citation Information

Patent Citations

  • Channel-expandable blood detection device

    CN211697816U