A clinical bladder urine volume real-time monitoring device based on ultrasound probe array

Abstract

The present invention discloses a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array, which includes an ultrasonic probe unit assembly, a cable and a display unit assembly; the ultrasonic probe unit assembly includes a strap and an ultrasonic probe array arranged in the middle of the strap; the display unit assembly includes a main control unit, an FPGA pulse generation unit, a channel isolation transmission unit, an analog multiplexing unit, a variable gain amplification unit, an ultrasonic envelope extraction unit, a button unit, a display unit and a power module unit. The FPGA pulse generation unit is connected to the channel isolation transmission unit, the channel isolation transmission unit is connected to the analog multiplexing unit, and then connected to the variable gain amplification unit, and then connected to the ultrasonic envelope extraction unit. The present invention has the advantages of small size, low cost, simple and efficient operation, accurate and reliable detection, etc., and is suitable for occasions such as tumor chemotherapy and other clinical operations where real-time monitoring of bladder urine volume is required during or after surgery.

Description

Technical Field

[0001] The invention relates to the field of medical devices, and in particular to a bladder urine volume real-time monitoring device. Background Art

[0002] In some clinical operations or after operations, especially when cancer patients undergo chemotherapy, the patient's bladder needs to maintain a certain amount of urine. The current solution is to organize ultrasound doctors and equipment to assist in regular checks of the patient's urine volume. However, there are problems such as the need to call on large B-ultrasound equipment and ultrasound department personnel, long surgical preparation time, and the inability to monitor the patient's bladder urine volume in real time during chemotherapy operations.

[0003] After investigation, in order to solve the problem of bladder urine volume detection, relevant patents have been studied and corresponding solutions have been proposed, such as:

[0004] 1. The patent application number is CN201410146741.0, and the name is "Intelligent Urine Volume Measurement System Based on Ultrasonic Waves". A method for measuring the depth of urine in a fixed container to indirectly calculate the volume of urine is proposed. However, this method requires the patient to excrete urine from the body and collect it in a container. Therefore, it is not suitable for real-time monitoring of clinical bladder urine volume and does not have the characteristics of online and real-time monitoring.

[0005] 2. Patent application number CN200910086390.8, entitled "A Portable Bladder Urine Volume Ultrasonic Measurement and Alarm System", proposes a method of using an ultrasonic probe fixed to the bladder wall and driven by a swing motor to perform multiple tests on the patient's bladder to calculate the average urine volume. However, due to the existence of the swing motor, this method is difficult to fix and the measurement range is limited to the swing motor angle. At the same time, this method is a depth detection of urine in the bladder, and the accuracy is not high, so it is not suitable for real-time monitoring of clinical bladder urine volume.

[0006] Therefore, a clinical bladder urine volume real-time monitoring device is urgently needed to solve the problem of rapid, accurate and real-time monitoring of the patient's bladder urine volume during or after clinical surgery. Summary of the invention

[0007] In view of this, the purpose of the present invention is to provide a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array to solve the problem that the current detection of patient bladder urine volume requires large instruments or equipment and professional ultrasound doctors.

[0008] The present invention discloses a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array, which comprises an ultrasonic probe unit component, a cable and a display unit component;

[0009] The ultrasound probe unit assembly comprises a strap and an ultrasound probe array arranged in the middle of the strap;

[0010] The display unit assembly includes a main control unit, an FPGA pulse generation unit, a channel isolation transmission unit, an analog multiplexing unit, a variable gain amplification unit, an ultrasonic envelope extraction unit, a button unit, a display screen unit and a power module unit;

[0011] The power module unit is respectively connected to the main control unit, the FPGA pulse generation unit, the channel isolation transmission unit, the analog multiplexing unit, the variable gain amplification unit, the ultrasonic envelope extraction unit, the button unit and the display screen unit;

[0012] The FPGA pulse generation unit is connected to the main control unit and the channel isolation transmission unit respectively, and the FPGA pulse generation unit is used to generate ultrasonic excitation signals in sequence according to the timing of the main control unit and send them to the channel isolation transmission unit;

[0013] The channel isolation transmitting unit is connected to the ultrasonic probe array through a cable. The channel isolation transmitting unit is controlled by the FPGA pulse generating unit to sequentially stimulate each ultrasonic probe in the ultrasonic probe array and receive ultrasonic echo signals.

[0014] The analog multiplexing unit is connected to the channel isolation transmitting unit and the main control unit respectively, and the analog multiplexing unit is used to receive the ultrasonic echo signals returned from the channel isolation transmitting unit in sequence under the control of the main control unit;

[0015] The variable gain amplification unit is connected to the analog multiplexing unit, and the variable gain amplification unit linearly amplifies the ultrasonic echo signal from the analog multiplexing unit and converts it into an ultrasonic echo signal within the range of 0-3.3V;

[0016] The ultrasonic envelope extraction unit is connected to the variable gain amplification unit and the main control unit respectively. The ultrasonic envelope extraction unit extracts the envelope signal of the ultrasonic echo signal from the variable gain amplification unit. The main control unit receives the envelope signal from the ultrasonic envelope extraction unit and determines whether there is urine at the ultrasonic probe position corresponding to the current envelope signal. If so, the pixel point at the corresponding position is marked white, and if not, it is marked black. After all the ultrasonic probe positions are detected, a black-and-white two-dimensional image is generated, and the current urine volume and whether the current urine volume is insufficient or excessive are calculated, and the black-and-white two-dimensional image and the calculation result are sent to the display unit for display;

[0017] The display screen unit is connected to the main control unit, and the display screen unit is used to display urine volume information;

[0018] The button unit is connected to the main control unit, and the button unit includes a switch button for controlling the start or stop of monitoring.

[0019] Furthermore, the display unit assembly also includes an indication unit connected to the power module unit and the main control unit, and the indication unit includes a power indicator light for indicating that the display unit assembly is powered on, an under-volume indicator light for indicating insufficient bladder urine volume, an over-volume indicator light for indicating excessive bladder urine volume, and an alarm buzzer for prompting insufficient or excessive bladder urine volume.

[0020] Furthermore, the button unit also includes an upward adjustment button for increasing the upper limit of the bladder urine volume and a downward adjustment button for decreasing the lower limit of the bladder urine volume.

[0021] Furthermore, the display unit assembly also includes a wireless module unit connected to the main control unit and the power module unit, and the wireless module unit is used to send the current patient's urine volume information to the nurse station or the monitoring center.

[0022] Furthermore, the ultrasound probe array includes 50 ultrasound probes.

[0023] Beneficial effects of the present invention:

[0024] 1. The clinical bladder urine volume real-time monitoring device based on the ultrasonic probe array of the present invention is small in size, easy to move and carry, and is suitable for situations where the patient's bladder urine volume needs to be monitored in real time during or after clinical surgery, especially during chemotherapy surgery for tumor patients.

[0025] 2. The clinical bladder urine volume real-time monitoring device of the present invention is based on an ultrasonic probe array. Its detection results are displayed in two-dimensional images. Doctors can directly observe the patient's bladder urine volume based on the images; the urine volume percentage can also be calculated by the controller unit and displayed by the display unit, which is convenient for use by non-professional imaging doctors.

[0026] 3. The clinical bladder urine volume real-time monitoring device based on the ultrasonic probe array of the present invention divides the high-frequency pulse signal required for ultrasonic excitation and the envelope signal processing of the ultrasonic echo into two controllers, namely the FPGA pulse generation unit and the main control unit. The two controllers are synchronized in time to ensure reliability and real-time performance, while improving monitoring efficiency.

[0027] 4. The clinical bladder urine volume real-time monitoring device of the present invention is based on an ultrasonic probe array, which is equipped with an under-volume indicator light, an over-volume indicator light and an alarm buzzer. When it is found that the patient's bladder urine volume is under-volume or over-volume, it will flash continuously, and remind the doctor to diagnose through light and sound.

[0028] 5. The clinical bladder urine volume real-time monitoring device based on the ultrasonic probe array of the present invention is equipped with a wireless module unit, which can send the current patient's urine volume percentage and under- or over-volume status to the nurse station or monitoring center. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 14 is a block diagram of the implementation principle of a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in an embodiment.

[0030] Figure 2 It is a circuit diagram of the first channel of a 50-channel isolated transmitting unit of a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in an embodiment.

[0031] Figure 3 1 is a circuit diagram of an analog multiplexing unit of a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in an embodiment.

[0032] Figure 4 4 is a circuit diagram of a variable gain amplification unit of a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in an embodiment.

[0033] Figure 5 4 is a circuit diagram of an ultrasonic envelope extraction unit of a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in an embodiment.

[0034] Figure 6 1 is a circuit diagram of a main control unit of a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in an embodiment.

[0035] Figure 7 : is a circuit diagram of an FPGA pulse generation unit of a clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in an embodiment.

[0036] Explanation of the reference numerals: 1-bladder urine volume display, 11-indication unit, 12-analog multiplexing unit, 13-variable gain amplification unit, 14-ultrasound envelope extraction unit, 15-button unit, 16-main control unit, 17-display unit, 18-wireless module unit, 19-FPGA pulse generation unit, 120-power module unit, 21-channel isolation transmission unit, 2-cable, 3-ultrasound probe strap, 31-ultrasound probe array, 32-strap, 33-Velcro. DETAILED DESCRIPTION

[0037] The present invention will be further described below in conjunction with the accompanying drawings and embodiments.

[0038] The clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array in this embodiment includes an ultrasonic probe unit assembly 3 , a cable 2 and a display unit assembly 1 .

[0039] The ultrasound probe unit assembly includes a strap 32 and an ultrasound probe array 31 disposed in the middle of the strap. In this embodiment, a Velcro 33 is disposed at the end of the strap 32 to facilitate fixing the strap on the patient's waist so that the ultrasound probe array 31 is opposite to the bladder. Of course, in different embodiments, the Velcro can also be replaced by other methods such as hidden buckles. In this embodiment, the ultrasound probe array 31 includes 50 15mm ultrasound probes, and the 50 ultrasound probes are arrayed in 5 rows and 10 columns; of course, in different embodiments, the number of ultrasound probes in the ultrasound probe array can also be designed to be other numbers as needed.

[0040] The display unit assembly 1 includes a main control unit 16, an FPGA pulse generating unit 19, a channel isolation transmitting unit 21, an analog multiplexing unit 12, a variable gain amplifying unit 13, an ultrasonic envelope extracting unit 14, a key unit 15, a display screen unit 17 and a power module unit 120. The power module unit is respectively connected to the main control unit, the FPGA pulse generating unit, the channel isolation transmitting unit, the analog multiplexing unit, the variable gain amplifying unit, the ultrasonic envelope extracting unit, the key unit and the display screen unit to supply power to each unit.

[0041] In this embodiment, because the ultrasonic probe array contains 50 ultrasonic probes, the corresponding channel isolation transmitting unit 21 is a 50-channel isolation transmitting unit, and the isolation chip model of the channel isolation transmitting unit is MD0100. In this embodiment, the chip model of the analog multiplexing unit 12 is ADG732; the chip model of the variable gain amplifier unit 13 is AD8311; the chip model of the ultrasonic envelope extraction unit 14 is LTC5507; the chip model of the main control unit 16 is STM32F405RGT6; the chip model of the FPGA pulse generation unit 19 is LCMXO2-1200HC-4TG100IR1. The circuit diagram between the various units of the display unit component is shown as follows. Figure 2-7 shown.

[0042] Of course, in different embodiments, the chip models of the channel isolation transmitting unit, the analog multiplexing unit, the variable gain amplifier circuit, the ultrasound envelope extraction unit, the main control unit and the FPGA pulse generating unit may also adopt other types.

[0043] The FPGA pulse generation unit is connected to the main control unit, which controls the timing of the FPGA pulse generation unit; the FPGA pulse generation unit is also connected to the channel isolation transmitting unit, which is used to generate ultrasonic excitation signals in sequence according to the timing of the main control unit and send them to the channel isolation transmitting unit.

[0044] The channel isolation transmitting unit is connected to the ultrasonic probe array via a cable 2. The channel isolation transmitting unit is controlled by the FPGA pulse generating unit to sequentially stimulate each ultrasonic probe in the ultrasonic probe array and receive ultrasonic echo signals with smaller amplitudes.

[0045] The analog multiplexing unit is connected to the channel isolation transmitting unit and the main control unit respectively. The analog multiplexing unit is used to receive the ultrasonic echo signals returned from the channel isolation transmitting unit in sequence under the control of the main control unit.

[0046] The variable gain amplification unit is connected to the analog multiplexing unit, and the variable gain amplification unit linearly amplifies the ultrasonic echo signal from the analog multiplexing unit and converts it into an ultrasonic echo signal within the range of 0-3.3V.

[0047] The ultrasonic envelope extraction unit is connected to the variable gain amplification unit and the main control unit respectively. The ultrasonic envelope extraction unit extracts the envelope signal of the ultrasonic echo signal from the variable gain amplification unit. The main control unit receives the envelope signal from the ultrasonic envelope extraction unit and determines whether there is urine at the ultrasonic probe position corresponding to the current envelope signal. If so, the pixel point at the corresponding position is marked white, and if not, it is marked black. After all the ultrasonic probe positions are detected, a black-and-white two-dimensional image is generated, and the current urine volume and whether the current urine volume is insufficient or excessive are calculated, and the black-and-white two-dimensional image and the calculation result are sent to the display unit for display.

[0048] The display screen unit is connected to the main control unit, and the display screen unit is used to display urine volume information.

[0049] The button unit is connected to the main control unit, and the button unit includes a switch button for controlling the start or stop of monitoring.

[0050] The working process of the clinical bladder urine volume real-time monitoring device based on the ultrasonic probe array in this embodiment is as follows:

[0051] Coupling agent is applied to the ultrasound probe array 31, and the strap 32 is worn on the patient's waist so that the ultrasound probe array 31 faces the patient's bladder 4. The display unit assembly 1 is turned on by the key unit, and the display unit 17 is observed to see whether a reasonable urine volume image and urine volume percentage appear. If not, the position and tightness of the strap 32 are appropriately adjusted; if yes, the patient's bladder urine volume can be monitored in real time.

[0052] First, the main control unit 16 generates a rising edge based on whether there is urine at the current ultrasonic probe position, and sends it to the FPGA pulse generation unit 19 through an IO port. The FPGA pulse generation unit 19 generates a 1MHz ultrasonic excitation signal with a certain frequency, and excites the ultrasonic probe at the next position in the ultrasonic probe array 31 after amplification by the 50-channel isolation transmitting unit 21. Then, when the main control unit 16 sends a rising edge to the FPGA pulse generation unit 19, it immediately controls the analog multiplexing unit 12 to connect to the ultrasonic probe at the next position, and enters the envelope signal sampling program to collect the envelope signal of the ultrasonic echo signal at the position of the ultrasonic probe, and so on, until all 50 ultrasonic probes in the ultrasonic probe band 3 are scanned.

[0053] The main control unit determines whether there is urine at the corresponding ultrasonic probe position through the collected current envelope signal. If there is urine, the pixel point at the corresponding position is marked white, and if not, it is marked black. After all the ultrasonic probe positions are detected, a black-and-white two-dimensional image is generated, and the current urine volume and whether the current urine volume is insufficient or excessive are calculated, and the black-and-white two-dimensional image and the calculation results are sent to the display unit for display. The specific method for judging the current urine volume is: assuming that the number of white pixels in the collected black-and-white two-dimensional image is x, the current bladder urine volume is (x / 50)×100%.

[0054] As an improvement to the above embodiment, the display unit assembly also includes an indication unit connected to the power module unit and the main control unit, and the indication unit includes a power indicator light for indicating that the display unit assembly has been powered on, an underflow indicator light for indicating insufficient bladder urine volume, an overflow indicator light for indicating excessive bladder urine volume, and an alarm buzzer for indicating insufficient or excessive bladder urine volume. If the monitoring result shows that the patient's urine volume is small, the underflow indicator light, the alarm buzzer, and the underflow label in the display unit 17 of the indication unit 11 will flash to warn the patient that the urine volume is insufficient, and it is necessary to wait until the patient's bladder urine volume reaches a certain amount before making the next clinical arrangement; if the detection result shows that the patient's urine volume is large, the overflow indicator light, the alarm buzzer, and the overflow label in the display unit 17 of the indication unit 11 will flash to warn the patient that the urine volume is excessive, and it is necessary to drain the excess urine in the patient's bladder. This improvement enables the doctor to be informed and reminded of the monitoring results through sound and light, which is convenient for non-professional doctors to use.

[0055] As an improvement to the above embodiment, the button unit further includes an upward adjustment button for increasing the upper limit of bladder urine volume and a downward adjustment button for decreasing the lower limit of bladder urine volume. This improvement enables the upper and lower limits of urine volume alarm to be adjusted upward or downward through the button unit 15 according to the specific conditions of different patients.

[0056] As an improvement to the above embodiment, the display unit assembly further includes a wireless module unit 18 connected to the main control unit and the power module unit, and the wireless module unit enables the current patient's urine volume information to be sent to a nurse station or a monitoring center.

[0057] The clinical bladder urine volume real-time monitoring device based on the ultrasonic probe array in this embodiment has the advantages of small size, low cost, simple and efficient operation, accurate and reliable detection, etc. It is suitable for occasions where real-time monitoring of bladder urine volume is required during or after clinical surgery such as tumor chemotherapy.

[0058] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the purpose and scope of the technical solution of the present invention, which should be included in the scope of the claims of the present invention.

Claims

1. A clinical bladder urine volume real-time monitoring device based on an ultrasonic probe array, characterized in that: Includes an ultrasound probe unit assembly, a cable, and a display unit assembly; The ultrasound probe unit assembly includes a strap and an ultrasound probe array disposed in the middle of the strap, wherein the ultrasound probe array includes 50 ultrasound probes arranged in a manner of 5 rows and 10 columns; The display unit assembly includes a main control unit, an FPGA pulse generation unit, a channel isolation transmission unit, an analog multiplexing unit, a variable gain amplification unit, an ultrasonic envelope extraction unit, a button unit, a display screen unit and a power module unit; The power module unit is respectively connected to the main control unit, the FPGA pulse generation unit, the channel isolation transmission unit, the analog multiplexing unit, the variable gain amplification unit, the ultrasonic envelope extraction unit, the button unit and the display screen unit; The FPGA pulse generation unit is connected to the main control unit and the channel isolation transmission unit respectively, and the FPGA pulse generation unit is used to generate ultrasonic excitation signals in sequence according to the timing of the main control unit and send them to the channel isolation transmission unit; The channel isolation transmitting unit is connected to the ultrasonic probe array through a cable. The channel isolation transmitting unit is controlled by the FPGA pulse generating unit to sequentially stimulate each ultrasonic probe in the ultrasonic probe array and receive ultrasonic echo signals. The analog multiplexing unit is connected to the channel isolation transmitting unit and the main control unit respectively, and the analog multiplexing unit is used to receive the ultrasonic echo signals returned from the channel isolation transmitting unit in sequence under the control of the main control unit; The variable gain amplification unit is connected to the analog multiplexing unit, and the variable gain amplification unit linearly amplifies the ultrasonic echo signal from the analog multiplexing unit and converts it into an ultrasonic echo signal within the range of 0-3.3V; The ultrasonic envelope extraction unit is connected to the variable gain amplification unit and the main control unit respectively. The ultrasonic envelope extraction unit extracts the envelope signal of the ultrasonic echo signal from the variable gain amplification unit. The main control unit receives the envelope signal from the ultrasonic envelope extraction unit and determines whether there is urine at the ultrasonic probe position corresponding to the current envelope signal. If there is urine, the pixel point at the corresponding position is marked white, and if not, it is marked black. After all the ultrasonic probe positions are detected, a black-and-white two-dimensional image is generated, and the current urine volume and whether the current urine volume is insufficient or excessive are calculated. The specific method for judging the current urine volume is: assuming that the number of white pixel points in the collected black-and-white two-dimensional image is x, the current bladder urine volume is (x / 50)×100%; the black-and-white two-dimensional image and the calculation result are sent to the display unit for display; The display screen unit is connected to the main control unit, and the display screen unit is used to display urine volume information; The button unit is connected to the main control unit, and the button unit includes a switch button for controlling the start of detection or the stop of monitoring.

2. The clinical bladder urine volume real-time monitoring device based on ultrasonic probe array according to claim 1, characterized in that: The display unit assembly also includes an indication unit connected to the power module unit and the main control unit, and the indication unit includes a power indicator light for indicating that the display unit assembly is powered on, an under-volume indicator light for indicating insufficient bladder urine volume, an over-volume indicator light for indicating excessive bladder urine volume, and an alarm buzzer for prompting insufficient or excessive bladder urine volume.

3. The clinical bladder urine volume real-time monitoring device based on ultrasonic probe array according to claim 1, characterized in that: The key unit also includes an upward adjustment key for increasing the upper limit of bladder urine volume and a downward adjustment key for decreasing the lower limit of bladder urine volume.

4. The clinical bladder urine volume real-time monitoring device based on ultrasonic probe array according to claim 1, characterized in that: The display unit assembly also includes a wireless module unit connected to the main control unit and the power module unit, and the wireless module unit is used to send the current patient's urine volume information to the nurse station or the monitoring center.

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