Radio frequency microneedle array control device, method and radio frequency microneedle therapeutic device

Abstract

The present invention discloses a radio frequency microneedle array control device, method and radio frequency microneedle therapeutic instrument, the device comprises: a microneedle array; a switch switching circuit, the input end of the switch switching circuit is connected to a power supply, the two first output ends of the switch switching circuit are electrically connected to the microneedle array through a PCB board, and the second output end of the switch switching circuit is electrically connected to a return electrode; a main controller, in a monopolar mode, the main controller controls the switch switching circuit to connect the power supply, the microneedle array and the return electrode; wherein the electrical polarity of multiple microneedle electrodes in the microneedle array is the same; in a bipolar mode, the main controller controls the switch switching circuit to connect the power supply and the microneedle array; wherein the electrical polarity of at least one microneedle electrode in the microneedle array is opposite to the electrical polarity of the remaining microneedle electrodes. The present invention can realize the switching of microneedle single and double electrodes, so that the width of the action area of ​​the microneedle in the horizontal direction and the depth in the vertical skin direction have a good therapeutic effect.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a radio frequency microneedle array control device, method and radio frequency microneedle therapeutic apparatus. Background Art

[0002] Radiofrequency microneedle therapy is a minimally invasive radiofrequency fractional technology that uses tiny microneedles to accurately apply radiofrequency (RF) energy to target tissues at different depths. This fundamentally changes the problems of traditional laser and radiofrequency treatments, such as uncertain depth, poorly controlled skin damage, and severe energy transmission attenuation. It also avoids side effects such as pigmentation and can be used for facial rejuvenation applications such as skin tightening and scar removal. It can also be used for the treatment of acne and axillary hyperhidrosis.

[0003] However, there are still many problems in the current microneedle fractional radiofrequency treatment process. For example, the microneedle electrodes are all designed with fixed positive and negative poles, that is, the same microneedle electrode always acts as the positive pole or always acts as the negative pole during the application process. This will lead to uneven energy during the treatment process, which is easy to affect the treatment effect and experience effect. Summary of the invention

[0004] The main purpose of the present invention is to propose a radio frequency microneedle array control device, method and radio frequency microneedle therapeutic instrument, aiming to realize the switching of microneedle single and double electrodes, so that the microneedle action area has a better therapeutic effect in both the horizontal width and the depth in the vertical skin direction.

[0005] To achieve the above object, the present invention provides a radio frequency microneedle array control device, the radio frequency microneedle array control device comprising:

[0006] Power supply;

[0007] Return electrode;

[0008] A microneedle array, comprising a PCB board and a plurality of microneedle electrodes arranged on the PCB board;

[0009] A switch switching circuit, wherein an input end of the switch switching circuit is connected to the power supply, two first output ends of the switch switching circuit are electrically connected to the microneedle array through a PCB board, and a second output end of the switch switching circuit is electrically connected to the return electrode;

[0010] A main controller, wherein the main controller has a monopolar mode and a bipolar mode. In the monopolar mode, the main controller controls the switch circuit to connect the power supply, the microneedle array and the return electrode; wherein the electrical polarity of the plurality of microneedle electrodes in the microneedle array is the same;

[0011] In the bipolar mode, the main controller controls the switch circuit to connect the power supply and the microneedle array; wherein the electrical polarity of at least one of the microneedle electrodes in the microneedle array is opposite to the electrical polarity of the remaining microneedle electrodes.

[0012] Optionally, the main controller is used to control the switch circuit to operate so as to control the microneedle array to switch between the monopolar mode and the bipolar mode.

[0013] Optionally, the main controller, when controlling the switch circuit to operate, controls the microneedle array to switch between the monopolar mode and the bipolar mode at least once.

[0014] Optionally, the main controller is used to control the switch circuit to operate so as to control the microneedle array to switch between the monopolar mode and the bipolar mode at a preset period.

[0015] Optionally, in bipolar mode, the main controller controls the switch circuit to switch the electrodes of each microneedle electrode of the microneedle array.

[0016] Optionally, the main controller switches the electrodes of each microneedle electrode of the microneedle array at least once when controlling the switch switching circuit to operate.

[0017] Optionally, one RF power supply or multiple independent RF power supplies are connected to the switch circuit.

[0018] The present invention also provides a radio frequency microneedle array control method, which is applied to the microneedle electrode array device as described above. The radio frequency microneedle array control device comprises:

[0019] Power supply;

[0020] Return electrode;

[0021] A microneedle array, comprising a PCB board and a plurality of microneedle electrodes arranged on the PCB board;

[0022] A switch switching circuit, wherein the input end of the switch switching circuit is connected to the power supply, the two first output ends of the switch switching circuit are electrically connected to the microneedle array through a PCB board, and the second output end of the switch switching circuit is electrically connected to the return electrode; characterized in that the radio frequency microneedle array control method comprises:

[0023] In the monopolar mode, the switch switching circuit is controlled to connect the power supply, the microneedle array and the return electrode; wherein the electrical polarity of the plurality of microneedle electrodes in the microneedle array is the same;

[0024] In bipolar mode, the switch switching circuit is controlled to connect the power supply and the microneedle array; wherein the electrical polarity of at least one of the microneedle electrodes in the microneedle array is opposite to the electrical polarity of the remaining microneedle electrodes.

[0025] Optionally, the radio frequency microneedle array control method further includes:

[0026] Controlling the microneedle array to switch between the monopolar mode and the bipolar mode at least once;

[0027] When the microneedle array is controlled to work in a bipolar mode, the switch circuit is controlled to switch the electrodes of each microneedle electrode of the microneedle array.

[0028] Optionally, the radio frequency microneedle array control method further includes:

[0029] Obtaining the impedance value of the tissue between the positive and negative electrodes of the microneedle and a preset impedance threshold;

[0030] The radio frequency energy output of the power supply is controlled according to the acquired impedance value of the tissue between the positive and negative electrodes of the microneedle and a preset impedance threshold.

[0031] Optionally, the step of obtaining the impedance value of the tissue between the positive and negative electrodes of the microneedle and a preset impedance threshold specifically includes:

[0032] After the microneedle electrode is inserted into the skin and reaches a preset depth, a current impedance value of the tissue between the positive and negative electrodes of the microneedle is obtained;

[0033] The preset impedance threshold is calculated based on the acquired current impedance value of the tissue between the positive and negative electrodes of the microneedle.

[0034] Optionally, the step of controlling the radio frequency energy output of the power supply according to the acquired impedance value of the tissue between the positive and negative electrodes of the microneedle and a preset impedance threshold specifically includes:

[0035] When the impedance value of the tissue between the positive and negative electrodes of the microneedle continues to increase and is greater than the preset impedance threshold, the power supply is controlled to reduce the radio frequency energy output.

[0036] The present invention also provides a radio frequency microneedle therapeutic apparatus, comprising the radio frequency microneedle array control device as described above.

[0037] The radio frequency microneedle array control device of the present invention is provided with a power supply, a return electrode, and a microneedle array; in a monopolar mode, the switch switching circuit is controlled by a main controller to connect the power supply, the microneedle array, and the return electrode; wherein the electrical polarity of the plurality of microneedle electrodes in the microneedle array is the same; in a bipolar mode, the switch switching circuit is controlled by a main controller to connect the power supply and the microneedle array; wherein the electrical polarity of at least one microneedle electrode in the microneedle array is opposite to the electrical polarity of the remaining microneedle electrodes. The radio frequency microneedle array control device of the present invention can realize the switching of single and double electrodes of microneedles, so that the width of the action area of ​​the microneedles in the horizontal direction and the depth in the vertical direction of the skin have a good therapeutic effect, which is conducive to improving the uniformity of energy output. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.

[0039] Figure 1 This is a schematic diagram of the circuit structure of an embodiment of a radio frequency microneedle array control device of the present invention;

[0040] Figure 2 for Figure 1 A schematic diagram of the electrode arrangement of an embodiment of a microneedle array;

[0041] Figure 3 It is a schematic diagram of a flow chart of an embodiment of a radio frequency microneedle array control method of the present invention;

[0042] Figure 4 It is a schematic diagram of a flow chart of an embodiment of a radio frequency microneedle array control method of the present invention;

[0043] Figure 5 It is a structural schematic diagram of an embodiment of a radio frequency microneedle therapeutic apparatus of the present invention.

[0044] Description of Figure Numbers:

[0045] Label name Label name 10 Power supply 40 Switching circuit 20 Return electrode 50 Main Controller 30 Microneedle array 100 case 200 Driving mechanism 110 Port 211 Encoder 210 Drive parts 230 Drive rod 220 Transmission rod 300 Cooling components 231 Pressure Sensors 320 Refrigeration unit 310 Heat dissipation device 322 Cold Junction 321 Hot End 410 PCB board 400 Microneedle components 430 Insulation layer 420 Microneedling 431 Temperature Sensor <![CDATA[4]]>

[0046] The realization of the purpose, functional features and advantages of the present invention will be further explained in conjunction with embodiments and with reference to the accompanying drawings. DETAILED DESCRIPTION

[0047] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0048] It should be noted that if the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0049] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or suggesting their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In addition, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in the field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0050] The term "and / or" in this article is only a description of the association relationship of the associated objects, indicating that there can be three relationships. For example, A and / or B can mean: A exists alone, A and B exist at the same time, and B exists alone. In addition, the character " / " in this article generally indicates that the associated objects before and after are in an "or" relationship.

[0051] The invention provides a radio frequency microneedle array control device.

[0052] Reference Figure 1 In one embodiment of the present invention, the radio frequency microneedle array 30 control device includes:

[0053] Power supply 10;

[0054] Return electrode 20;

[0055] The microneedle array 30 includes a PCB board and a plurality of microneedle electrodes 420 disposed on the PCB board;

[0056] A switch switching circuit 40, wherein an input end of the switch switching circuit 40 is connected to the power supply 10, two first output ends of the switch switching circuit 40 are electrically connected to the microneedle array 30 through a PCB board, and a second output end of the switch switching circuit 40 is electrically connected to the return electrode 20;

[0057] A main controller 50, wherein the main controller 50 has a monopolar mode and a bipolar mode. In the monopolar mode, the main controller 50 controls the switch circuit 40 to connect the power supply 10, the microneedle array 30 and the return electrode 20; wherein the electrical polarity of the plurality of microneedle electrodes 420 in the microneedle array 30 is the same;

[0058] In the bipolar mode, the main controller 50 controls the switch circuit 40 to connect the power supply 10 and the microneedle array 30 ; wherein the electrical polarity of at least one of the microneedle electrodes 420 in the microneedle array 30 is opposite to the electrical polarity of the remaining microneedle electrodes 420 .

[0059] In this embodiment, the material of the microneedle electrode 420 can be selected from any conductive metal or other conductive material, such as stainless steel, gold, silver, platinum, platinum-iridium alloy, tungsten, etc., and the surface material of the microneedle electrode 420 is a material with good biocompatibility, such as 304 stainless steel, 316 stainless steel, gold, platinum, platinum-iridium alloy, etc. The entire microneedle array 30 has at least one microneedle with polarity opposite to that of other microneedles, that is, the microneedle array 30 has both positive and negative electrodes. The microneedle electrodes 420 on the microneedle array 30 can be set as positive electrodes or negative electrodes as needed, and the electrodes of each microneedle can be switched, and alternately serve as positive and negative electrodes in turn in different operating time periods. The microneedle electrode 420 is not fixed in the alternating position of the positive and negative electrodes, which avoids the same microneedle electrode 420 always acting as a positive electrode or a negative electrode during the application process. Specifically, it can be achieved by passing voltages of different polarities on each microneedle. The polarity of the electrodes of each microneedle can be the same as or different from that of the electrodes of the adjacent microneedles. For example, the electrodes of the microneedle array 30 can be arranged in rows (columns) in a staggered manner, that is, the electrodes of the microneedles in one row (column) are arranged as positive electrodes, and the electrodes of the microneedles in the adjacent row (column) are arranged as negative electrodes. Figure 2 As shown, the electrode of each microneedle is opposite to the electrode of its adjacent microneedle, that is, the microneedle electrodes 420 in each row and each column are arranged in a positive and negative staggered manner. The PCB board can be used to install the microneedle array 30, which can be a PCB board or a mounting substrate of the microneedle array 30. In one embodiment, the radio frequency microneedle array 30 control device also includes a driving structure provided with a motor, and the driving structure can drive the PCB board to move, thereby driving the microneedle array 30 to move, and the microneedle array 30 can be inserted into the skin, and after reaching the specified depth, the microneedle needle tip begins to release radio frequency energy to perform radio frequency treatment.

[0060] The output frequency of the power supply 10 can be 0.3MHz-100MHz, and the power supply 10 can be a continuous output power supply or a pulse output power supply or a continuous and pulse output power supply. The power supply 10 can be an external power supply or a rechargeable lithium battery. The power supply 10 can be provided with a power management chip and a rechargeable battery. The output voltage of the power supply 10 is controllable. For example, the main controller 50 can output different control signals to the power supply 10, so that the power supply 10 outputs a pulse voltage. The power supply 10 can be logically connected to the main controller 50 through the power management chip, so that the power management chip can realize the functions of managing charging, discharging, and power consumption management, as well as the switching and selection of the discharge mode, constant power discharge or pulse discharge.

[0061] Furthermore, the number of the power supply 10 may be one or more. When multiple power supply units are provided, the multiple power supply units are respectively connected to the switch switching circuit;

[0062] Microneedle therapy generally achieves constant power output through impedance detection feedback. The present embodiment is also provided with an impedance detection circuit, which is connected to each of the microneedle electrodes in the microneedle array. The output end of the impedance detection circuit is connected to the main controller. The main controller 50 is also used to control the power supply unit to provide corresponding power supply voltage to the corresponding microneedle electrode according to the positive and negative impedances of each of the microneedle electrodes detected by the impedance detection circuit.

[0063] The impedance detection circuit detects the impedance between the positive and negative microneedle electrodes 420, and the output end is electrically connected to the main controller 50. The main controller 50 can also control the independent RF power supply or each power supply unit to work according to the impedance sensor feedback data to adjust the RF output power of the microneedle electrode 420.

[0064] In the monopolar mode, in an embodiment where the power supply 10 is provided with a single power source and an independent RF power supply, the main controller 50 can control the independent RF power supply according to the impedance sensor feedback data to adjust the RF output power of the microneedle electrode 420 of the microneedle array as a whole, thereby ensuring that the total output power is constant.

[0065] In the embodiment where the power supply 10 is configured as a plurality of independent RF power supplies, an independent RF power supply can be configured for each microneedle electrode 420 (in bipolar mode, each microneedle electrode pair), and each microneedle electrode is provided with an impedance sensor to detect the impedance of each microneedle electrode 420 and adjust the output power according to the impedance, so as to ensure that the output power of each needle is the same, and adopt a group power supply mode, that is, each group of microneedle electrodes 420 is powered by an independent RF power supply. The main controller 50 controls the corresponding power supply unit to adjust the output (adjust the frequency or pulse width or voltage amplitude) according to the feedback of the detected impedance. The purpose of using multiple independent power supplies in this embodiment is to achieve precise control to ensure uniform energy between treatment areas.

[0066] In bipolar mode, the impedance between each group of positive and negative microneedle electrodes 420 of the microneedle array 30 can be detected, and the output power can be adjusted according to the impedance between each group of positive and negative microneedle electrodes 420. Specifically, the microneedle array 30 can be set to multiple electrode pairs, and the voltage of each electrode pair is adjustable. Correspondingly, the number of power supplies 10 can be set to multiple, and each electrode pair is correspondingly provided with a power supply 10; or, the power supply 10 is provided with multiple output terminals and multiple control switches (not shown in the figure), and each output terminal and control switch are connected to an electrode pair; each control switch is closed to supply power to the corresponding electrode pair. The power supply 10 of this embodiment can be provided with multiple independent power supply units, and one power supply unit supplies power to one electrode pair. Alternatively, a power supply 10 is provided, and the power supply 10 can be provided with multiple output terminals, and one output terminal and one control switch correspond to one electrode pair. When it is necessary to supply power to a certain electrode pair, the conduction degree and conduction frequency of the control switch corresponding to the electrode pair can be controlled to adjust the frequency or pulse width or voltage amplitude output to the microneedle electrode 420. Of course, in other embodiments, the microneedles can also be set as multiple electrode groups, each electrode group includes the same number of positive microneedle electrodes 420 and negative microneedle electrodes 420, and the microneedles are grouped and powered by the power supply 10, and each microneedle is arranged alternately, so that multiple microneedle electrodes 420 can be arranged with appropriate density on a limited target plane, and the spacing distance between adjacent microneedle electrodes 420 is ensured to prevent the proximity effect. In the bipolar mode, multiple independent RF power supplies can be used, so that the temperature of the heat diffusion area of ​​each group of microneedles can be accurately controlled to achieve a better treatment effect.

[0067] The main controller 50 can be a microprocessor such as a single-chip microcomputer, DSP and FPGA. Of course, in some embodiments, it can also be implemented by using a dedicated chip for radio frequency microneedle therapeutic apparatus, which is not limited here. Those skilled in the art can integrate some hardware circuits and software programs or algorithms in the main controller 50, use various interfaces and lines to connect the various parts of the entire radio frequency microneedle array 30 control device, and execute or execute the software programs and / or modules in the main controller 50, and call the data in the main controller 50 to execute various functions and process data of the radio frequency microneedle array control device, thereby monitoring the radio frequency microneedle array control device as a whole. The main controller 50 stores a variety of working modes, which can be selected and switched according to the needs of the user. The working mode includes a monopolar mode and a bipolar mode. In the bipolar mode, it can also include the switching cycle and duration of each electrode polarity. The user can also choose a custom mode or a preset mode. The preset mode can set different working frequencies, voltage pulses and electrode energization working durations of the microneedles according to statistics, research or experience values, and then form different options for the user to choose. The custom setting is that the user sets the working duration and working voltage of the microneedles according to their own needs.

[0068] Among them, the main controller 50 can specifically control the switch switching circuit 40 to switch the microneedle array 30 between the monopolar mode and the bipolar mode. And in a treatment process, the microneedle array 30 is controlled to switch between the monopolar mode and the bipolar mode at least once. Alternatively, the main controller 50 can also control the switch switching circuit 40 to control the microneedle array 30 to switch between the monopolar mode and the bipolar mode at a preset cycle. In a specific embodiment, the duration T of a treatment in the treatment stage can be set to a range of 10ms to 12s, and in the two working modes of monopolar mode and bipolar mode, the duration T1 in each working mode can be in the range of 5ms to 5s.

[0069] The radio frequency microneedle array 30 control device of the present invention is provided with a power supply 10, a return electrode 20, and a microneedle array 30; in the monopolar mode, the main controller 50 is used to control the switch circuit 40 to connect the power supply 10, the microneedle array 30, and the return electrode 20; wherein the electrical polarity of the plurality of microneedle electrodes 420 in the microneedle array 30 is the same; in the bipolar mode, the main controller 50 is used to control the switch circuit 40 to connect the power supply 10 and the microneedle array 30; wherein the electrical polarity of at least one microneedle electrode 420 in the microneedle array 30 is opposite to the electrical polarity of the remaining microneedle electrodes 420. The radio frequency microneedle array 30 control device of the present invention can realize the switching of the microneedle single and double electrodes, so that the width of the microneedle action area in the horizontal direction and the depth in the vertical direction of the skin have a good therapeutic effect, which is conducive to improving the uniformity of energy output.

[0070] Reference Figure 1 In one embodiment, the main controller 50 switches the electrodes of each microneedle electrode 420 of the microneedle array 30 at least once when controlling the switch circuit 40 to work.

[0071] The switch circuit 40 is based on the control of the main controller 50, and is used to connect the positive and negative power supplies of the power supply 10 to the microneedle electrode 420, so that the microneedle electrode 420 works as a positive electrode or a negative electrode. In the monopolar mode, the polarity of each electrode in the microneedle array 30 is the same, for example, all are positive electrodes. At this time, the power supply 10 provides positive power to each electrode of the microneedle array 30 under the control of the switch circuit 40, and the negative electrode of the power supply 10 is connected to the return electrode 20 under the control of the switch circuit 40. When the radio frequency microneedle array 30 controls the device, the return electrode 20 is attached to the surface of the human body when working, and forms a conductive loop with the power supply 10, the microneedle electrode 420 of the microneedle array 30, the switch circuit 40, and the human body (the return electrode 20 is generally attached to the back of the neck when treating the face, and is generally attached to the back when treating the abdomen).

[0072] In the bipolar mode, the switch switching circuit 40 introduces the power supply 10 into the microneedle array 30, and under the control of the switch switching circuit 40, the positive and negative electrodes of the power supply 10 are respectively connected to each microneedle electrode 420, and there is at least one negative microneedle electrode 420 in the microneedle array 30, and the remaining microneedle electrodes 420 can be all or partly set as positive microneedle electrodes 420. Alternatively, there is at least one positive microneedle electrode 420, and the remaining microneedle electrodes 420 can be all or partly set as negative microneedle electrodes 420. The main controller 50 controls the switch switching circuit 40 to switch the electrodes of each microneedle electrode 420 of the microneedle array 30, that is, the polarity of each microneedle electrode 420 can be switched. For example, after the microneedle array 30 has been working for a period of time T', all the microneedles of the microneedle array 30 are switched to the power supply end through the switch control (the two ports A and B of the power supply 10, the microneedles connected to port A are switched to be connected to port B, and the microneedles connected to port B are switched to be connected to port A at the same time), and the power supply end is switched at least once each time in the bipolar mode. In the bipolar mode, the microneedles connected to both ends of the RF power supply will have different corresponding heat diffusion areas, which is mainly caused by the power supply characteristics, which will cause uneven heat diffusion areas and affect the treatment effect. The above effects can be eliminated by switching the power supply end.

[0073] The switch switching circuit 40 can also control the microneedle array 30 to switch between the monopolar mode and the bipolar mode. Specifically, during treatment, the initial working mode can be the monopolar mode or the bipolar mode. After a period of time T1, the working mode is switched, that is, from the monopolar mode to the bipolar mode, or from the bipolar mode to the monopolar mode. The working mode is switched at least once during the entire treatment stage. The action area (heat diffusion area) in the two modes is different. The depth of the action area in the monopolar mode is deeper than that in the bipolar mode. The action area of ​​the bipolar mode is mainly between two needles with opposite polarities and is relatively wide in the horizontal direction. In order to expand the action area and improve the treatment effect, this embodiment adopts a single-bipolar switching mode so that the action area can achieve the desired effect in terms of the width in the horizontal direction and the depth in the vertical direction of the skin.

[0074] The present invention also provides a radio frequency microneedle array control method, which is applied to the microneedle electrode array device as described above. The radio frequency microneedle array control device comprises:

[0075] Power supply;

[0076] Return electrode;

[0077] A microneedle array, comprising a PCB board and a plurality of microneedle electrodes arranged on the PCB board;

[0078] A switch switching circuit, wherein an input end of the switch switching circuit is connected to the power supply, two first output ends of the switch switching circuit are electrically connected to the microneedle array through a PCB board, and a second output end of the switch switching circuit is electrically connected to the return electrode;

[0079] Reference Figure 3 , the radio frequency microneedle array control method comprises:

[0080] Step S100, in the monopolar mode, controlling the switch switching circuit to connect the power supply, the microneedle array and the return electrode; wherein the electrical polarity of the plurality of microneedle electrodes in the microneedle array is the same;

[0081] Step S200, in bipolar mode, control the switch switching circuit to connect the power supply and the microneedle array; wherein the electrical polarity of at least one of the microneedle electrodes in the microneedle array is opposite to the electrical polarity of the remaining microneedle electrodes. In this embodiment, the switch switching circuit is based on the control of the main controller, and is used to connect the positive and negative power supplies of the power supply to the microneedle electrodes, so that the microneedle electrodes work as positive or negative electrodes. In the monopolar mode, the polarity of each electrode in the microneedle array is the same, for example, all are positive electrodes. At this time, the power supply provides positive power to each electrode of the microneedle array under the control of the switch switching circuit, and the negative electrode of the power supply is connected to the return electrode under the control of the switch switching circuit. When the radio frequency microneedle array control device is in operation, the return electrode is attached to the surface of the human body, and forms a conductive loop with the power supply, the microneedle electrodes of the microneedle array, the switch switching circuit, and the human body (the return electrode is generally attached to the back of the neck when treating the face, and is generally attached to the back when treating the abdomen).

[0082] In bipolar mode, the switch switching circuit introduces the power supply into the microneedle array, and under the control of the switch switching circuit, the positive and negative electrodes of the power supply are respectively connected to each microneedle electrode. There is at least one negative microneedle electrode in the microneedle array, and the remaining microneedle electrodes can be all or partly set as positive microneedle electrodes. Alternatively, there is at least one positive microneedle electrode, and the remaining microneedle electrodes can be all or partly set as negative microneedle electrodes. The main controller controls the switch switching circuit to switch the electrodes of each microneedle electrode in the microneedle array, that is, the polarity of each microneedle electrode can be switched. For example, after the microneedle array continues to work for a period of time T', all microneedles in the microneedle array are switched by switch control (the two ports A and B of the power supply, the microneedle connected to port A is switched to be connected to port B, and the microneedle connected to port B is switched to be connected to port A), and the power supply end is switched at least once in each bipolar mode. In bipolar mode, the microneedles connected at both ends of the RF power supply will have different corresponding heat diffusion areas, which is mainly caused by the power supply characteristics. This will lead to uneven heat diffusion areas and affect the treatment effect. The above influence can be eliminated by switching the power supply end.

[0083] In one embodiment, the radio frequency microneedle array control method further includes:

[0084] Step S300, controlling the microneedle array to switch between the monopolar mode and the bipolar mode at least once;

[0085] Step S400, when controlling the microneedle array to work in a bipolar mode, controlling the switch circuit to switch the electrodes of each microneedle electrode of the microneedle array.

[0086] The switch switching circuit can also control the microneedle array to switch between the monopolar mode and the bipolar mode. Specifically, during treatment, the initial working mode can be the monopolar mode or the bipolar mode. After a period of time T1, the working mode is switched, that is, from the monopolar mode to the bipolar mode, or from the bipolar mode to the monopolar mode. The working mode is switched at least once during the entire treatment stage. The action area (heat diffusion area) in the two modes is different. The depth of the action area in the monopolar mode is deeper than that in the bipolar mode. The action area of ​​the bipolar mode is mainly between two needles with opposite polarities and is relatively wide in the horizontal direction. In order to expand the action area and improve the treatment effect, this embodiment adopts a single-bipolar switching mode so that the action area can achieve the expected effect in terms of the width in the horizontal direction and the depth in the vertical direction of the skin.

[0087] In one embodiment, the radio frequency microneedle array control method further includes:

[0088] Step S500, obtaining the impedance value of the tissue between the positive and negative electrodes of the microneedle and a preset impedance threshold;

[0089] In this embodiment, an impedance sensor may be disposed on the microneedle electrode to detect the impedance between the positive and negative microneedle electrodes. For example, in a bipolar mode, an impedance sensor is disposed on each microneedle electrode pair to detect the impedance between each microneedle electrode. The preset impedance threshold may be obtained by the following steps:

[0090] After the microneedle electrode is inserted into the skin and reaches a preset depth, a current impedance value of the tissue between the positive and negative electrodes of the microneedle is obtained;

[0091] The preset impedance threshold is calculated based on the acquired current impedance value of the tissue between the positive and negative electrodes of the microneedle.

[0092] The radio frequency microneedle array control device also includes a driving structure equipped with a motor, which can drive the PCB board to move, and then drive the microneedle array to move. The microneedle array can penetrate into the skin, and after reaching the specified depth, the microneedle needle tip begins to release radio frequency energy for radio frequency treatment.

[0093] Depending on the working mode of the radio frequency microneedle array control device, the initial impedance value of the microneedle when inserted is also different. In the initial stage of microneedle treatment, the microneedle electrode is controlled to penetrate the skin, and after reaching the preset depth, the initial impedance values ​​of the monopolar mode and bipolar mode can be obtained respectively through the impedance sensor and mode switching. For example, in the monopolar mode, the initial impedance value is Z1, and in the bipolar mode, the initial impedance value is Z2. According to the obtained initial impedance value, the preset impedance threshold is set: in the monopolar mode, the impedance threshold is k1×Z1+A, and the bipolar mode impedance threshold is k2×Z2+B, where k1, k2, A and B are constants pre-set according to experimental data.

[0094] Step S600: Control the radio frequency energy output of the power supply according to the obtained impedance value of the tissue between the positive and negative electrodes of the microneedle and the preset impedance threshold. Specifically:

[0095] When the impedance value of the tissue between the positive and negative electrodes of the microneedle continues to increase and is greater than the preset impedance threshold, the power supply is controlled to reduce the radio frequency energy output.

[0096] In this embodiment, when the radio frequency microneedle array control device is powered on, after the microneedle electrode is inserted into the skin and reaches a preset depth, and after the initial impedance value of the microneedle when inserted is obtained, the power supply output parameter can be determined according to the obtained initial impedance value, and the RF energy can be output, wherein the corresponding relationship between the power supply output and the impedance value is pre-set in the system. During the treatment process of the radio frequency microneedle array control device, the tissue impedance of the treatment area changes linearly with the increase of temperature, first gradually decreases and then gradually increases. After reaching a certain temperature, the impedance will increase sharply. At this time, the impedance value of the tissue between the positive and negative electrodes of the microneedle during the treatment process can be obtained by the impedance sensor. When the impedance is detected to increase gradually and reach the preset impedance threshold, the RF energy output is reduced, otherwise the current RF energy output is maintained. In this way, the independent radio frequency power supply can be controlled according to the feedback data of the impedance sensor to adjust the RF output power of the microneedle electrode of the microneedle array as a whole, thereby ensuring safety and treatment effect.

[0097] The present invention also proposes a radio frequency microneedle therapeutic apparatus, including the radio frequency microneedle array control device as described above. The detailed structure of the radio frequency microneedle array control device can refer to the above embodiment, and will not be repeated here; it can be understood that since the above radio frequency microneedle array control device is used in the radio frequency microneedle therapeutic apparatus of the present invention, the embodiment of the radio frequency microneedle therapeutic apparatus of the present invention includes all technical solutions of all embodiments of the above radio frequency microneedle array control device, and the technical effects achieved are also exactly the same, and will not be repeated here.

[0098] Among them, the radio frequency microneedle therapeutic device includes:

[0099] A housing 100, wherein one end of the housing 100 is provided with a through opening 110;

[0100] A driving mechanism 200 is installed on the housing 100;

[0101] A cooling assembly 300 is installed in the housing 100 and connected to the driving mechanism 200; and

[0102] The microneedle assembly 400 is connected to the side of the cooling assembly 300 facing the through port 110. The cooling assembly 300 is used to cool and lower the temperature of the microneedle assembly 400. The driving mechanism 200 is used to drive the cooling assembly 300 to move, so as to drive the microneedle assembly 400 to extend out of the shell 100 through the through port 110 or move back into the shell 100.

[0103] Specifically, the microneedle assembly 400 includes a PCB board and a microneedle array, the microneedle array is provided with a plurality of microneedles, each microneedle electrode 420 is electrically connected to the PCB board 410, or the microneedle array can also be welded on the PCB board, and each microneedle electrode 420 can be used to generate radio frequency current (a high-frequency alternating electromagnetic wave) to allow RF energy to act on human tissue. In the related art, during the treatment process, the radio frequency current will continuously pass through the microneedle, causing the microneedle to heat up, and the heated microneedle will cause the human tissue to adhere to it, thus causing unnecessary damage to the human tissue and affecting the subsequent treatment effect.

[0104] The driving mechanism 200 drives the connected cooling component 300 to drive the cooling component 300 to move, thereby driving the microneedle component 400 to extend out of the shell 100 through the opening 110 of the shell 100 or move back into the shell 100. When the microneedle component 400 extends out of the shell 100, its microneedle array can penetrate into the skin, and release RF energy after reaching the specified depth to perform radio frequency treatment. At the same time, during the radio frequency treatment process, the cooling component 300 can be refrigerated to cool the microneedle component 400 connected thereto, thereby effectively avoiding the adhesion between human tissue and the microneedle electrode 420 due to the heating of the microneedle electrode 420, avoiding unnecessary damage to human tissue, thereby reducing the patient's pain and improving the treatment effect and safety.

[0105] Furthermore, if Figure 4As shown, the cooling assembly 300 includes a heat sink 310 and a refrigeration device 320, the driving mechanism 200 is connected to the heat sink 310, the refrigeration device 320 is connected to the heat sink 310, and the microneedle assembly 400 is connected to the refrigeration device 320. It can be understood that the refrigeration device 320 is used for cooling and heat exchange with the microneedle assembly 400, so as to achieve the purpose of cooling the microneedle assembly 400. In addition, according to the law of conservation of energy, the refrigeration device 320 will also emit heat while generating cold. Therefore, in this embodiment, the heat sink 310 is arranged in the housing 100 to dissipate heat from the refrigeration device 320. Of course, in other embodiments, the heat sink 310 may not be arranged in the housing 100, and the refrigeration device 320 dissipates heat naturally by contacting with the air.

[0106] In this embodiment, the heat dissipation device 310 includes a heat-conducting shell and a coolant. The heat-conducting shell is arranged to form a liquid storage chamber, and the coolant is contained in the liquid storage chamber. Optionally, the heat-conducting shell can be made of a metal material with good thermal conductivity such as compressed aluminum, and the coolant can be salt water or other liquids. It can be understood that the heat dissipation device 310 is essentially an energy storage device for temporarily storing heat conducted from the refrigeration device 320, and the heat in the energy storage device will slowly dissipate into the air. In other embodiments, the heat dissipation device 310 can also use a fan and / or a radiator to dissipate heat, but this heat dissipation method will generate relatively large noise.

[0107] In this embodiment, Figure 4 As shown, the refrigeration device 320 is a semiconductor refrigerator, which includes a hot end 321 and a cold end 322 arranged in a stacked manner. The hot end 321 is connected to the heat dissipation device 310, and the microneedle assembly 400 is connected to the cold end 322. A semiconductor refrigerator refers to a device that uses the thermal-electric effect of a semiconductor to produce cold energy. Specifically, when two different metals are connected by a conductor and a direct current is connected, the temperature at one connection point decreases, and the connection point is the cold end 322; the temperature at the other connection point increases, which is called the hot end 321. In the technical solution of this embodiment, by connecting the microneedle assembly 400 to the cold end 322 of the semiconductor refrigerator, the heat of the microneedle electrode 420 in the microneedle assembly 400 can be transferred to the cold end 322, thereby reducing the temperature of the microneedle electrode 420. Of course, in other embodiments, other refrigeration devices 320 may also be used, such as a heat exchanger. However, as a refrigeration device 320, a semiconductor refrigerator has the advantages of simple structure, small size and fast cooling, which is conducive to reducing the overall volume of the radio frequency microneedle therapeutic device.

[0108] As is known from the foregoing description, the microneedle assembly 400 includes an electrically connected PCB board 410 and a microneedle array, and the microneedle array is mounted on the PCB board 410. Among them, it is worth noting that the microneedle array should be arranged corresponding to the through-port 110 so as to extend out of the housing 100 or move back into the housing 100 through the through-port 110. In addition, the microneedle assembly 400 also includes an insulating layer 430, and the insulating layer 430 is arranged between the cold end 322 and the PCB board 410. Specifically, the microneedle array runs through the PCB board 410 and is connected to the insulating layer 430. It can be understood that the insulating layer 430 can conduct the heat of the microneedle array to the cold end 322, and at the same time can avoid conductive contact between the microneedle array and the cold end 322. The insulating layer can be optionally implemented using a material with higher thermal conductivity, such as ceramic.

[0109] Furthermore, if Figure 1 As shown, a temperature sensor 431 is also installed in the insulating layer 430, and the temperature sensor 431 is electrically connected to the central control unit of the radio frequency microneedle therapeutic apparatus. The central control unit can be the main controller in the radio frequency microneedle array control device, or the CPU in the radio frequency microneedle therapeutic apparatus, and the main controller in the radio frequency microneedle array control device can also be the CPU in the radio frequency microneedle therapeutic apparatus.

[0110] It can be understood that the temperature sensor 431 is used to detect the temperature of the microneedle electrode 420, and convert the detected temperature into an electrical signal and feed it back to the central control unit of the radio frequency microneedle therapeutic device, so that the central control unit can monitor the temperature of the microneedle electrode 420 in real time. Specifically, the temperature value of the microneedle electrode 420 is first obtained through the temperature sensor 431, and the central control unit determines whether the temperature of the microneedle electrode 420 exceeds the preset primary temperature threshold or the final warning threshold. If it exceeds the primary temperature threshold, the central control unit will control the refrigeration device 320 to start refrigeration or increase the power of the refrigeration device 320; if the temperature exceeds the final warning threshold, the central control unit will control the drive 210 to stop running and stop the RF energy output.

[0111] Furthermore, if Figure 4 As shown, the driving mechanism 200 includes a driving member 210, a transmission member 220 and a driving rod 230. The driving member 210 and the driving rod 230 are connected by the transmission member 220, and the cooling assembly 300 is connected to the driving rod 230. It can be understood that the driving member 210 drives the driving rod 230 to move through the transmission member 220, thereby driving the cooling assembly 300 to move, and the microneedle assembly 400 connected to the cooling assembly 300 also moves accordingly.

[0112] In this embodiment, a pressure sensor 231 is provided at the end of the driving rod 230 facing the cooling assembly 300, and the pressure sensor 231 is electrically connected to the central control unit. It can be understood that the speed at which the microneedle array penetrates the skin directly affects the human body's pain sensation, and different people and different parts of the skin require different forces when penetrated. The central control unit can adjust the power of the driving member 210 by receiving the pressure feedback of the pressure sensor 231, ensuring that the microneedle array can quickly penetrate the human tissue and improve the experience effect.

[0113] In this embodiment, the driving member 210 is a motor, and the motor is equipped with an encoder 211. It can be understood that the encoder 211 can feedback the precise motor stroke, and then feedback the actual insertion depth of the microneedle electrode 420 into the human tissue. The central control unit can obtain a correction value of the insertion depth through the PID algorithm according to the difference between the insertion depth value h1 set by the user and the feedback value h2 of the encoder 211, and feedback it to the motor to ensure the accuracy of the insertion depth of the microneedle electrode 420 into the human tissue.

[0114] Optionally, a fit sensor can be provided on the end surface of the shell 100 that contacts the skin to detect whether the RF microneedle therapeutic device fits the skin during treatment. This helps to guide the user to operate the therapeutic device correctly, avoid the microneedle electrode 420 releasing RF energy on the skin surface and causing skin burns, and further improve the safety of the treatment process.

[0115] The above descriptions are only optional embodiments of the present invention, and are not intended to limit the patent scope of the present invention. All equivalent structural changes made using the contents of the present invention's specification and drawings, or directly / indirectly applied in other related technical fields, are included in the patent protection scope of the present invention.

Claims

1. A radio frequency microneedle array control device, characterized in that: The radio frequency microneedle array control device comprises: Power supply; Return electrode; A microneedle array, comprising a PCB board and a plurality of microneedle electrodes arranged on the PCB board; A switch switching circuit, wherein an input end of the switch switching circuit is connected to the power supply, a first output end of the switch switching circuit is electrically connected to the microneedle array via a PCB board, and a second output end of the switch switching circuit is electrically connected to the return electrode; A main controller, wherein the main controller has a monopolar mode and a bipolar mode. In the monopolar mode, the main controller controls the switch circuit to connect the power supply, the microneedle array and the return electrode; wherein the electrical polarity of the plurality of microneedle electrodes in the microneedle array is the same; In the bipolar mode, the main controller controls the switch circuit to connect the power supply and the microneedle array; wherein the electrical polarity of at least one microneedle electrode in the microneedle array is opposite to the electrical polarity of the remaining microneedle electrodes; The main controller is used to control the switch circuit to operate so as to control the microneedle array to switch between the monopolar mode and the bipolar mode; The main controller controls the microneedle array to switch between the monopolar mode and the bipolar mode at least once when controlling the switch switching circuit to work.

2. The radio frequency microneedle array control device according to claim 1, characterized in that: The main controller is used to control the switch circuit to operate so as to control the microneedle array to switch between the monopolar mode and the bipolar mode at a preset period.

3. The radio frequency microneedle array control device according to claim 1, characterized in that: In the bipolar mode, the main controller controls the switch circuit to switch the electrodes of each microneedle electrode of the microneedle array.

4. The radio frequency microneedle array control device according to claim 3, characterized in that: The main controller switches the electrodes of each microneedle electrode of the microneedle array at least once when controlling the switch switching circuit to work.

5. The radio frequency microneedle array control device according to any one of claims 1 to 4, characterized in that: The power supply comprises: A radio frequency power supply or a plurality of mutually independent radio frequency power supplies, wherein the radio frequency power supply is connected to the switch circuit.

6. A radio frequency microneedle array control method, applied to the radio frequency microneedle array control device according to any one of claims 1 to 5, the radio frequency microneedle array control device comprising: Power supply; Return electrode; A microneedle array, comprising a PCB board and a plurality of microneedle electrodes arranged on the PCB board; A switch switching circuit, wherein the input end of the switch switching circuit is connected to the power supply, the two first output ends of the switch switching circuit are electrically connected to the microneedle array through a PCB board, and the second output end of the switch switching circuit is electrically connected to the return electrode; characterized in that the radio frequency microneedle array control method comprises: In the monopolar mode, the switch switching circuit is controlled to connect the power supply, the microneedle array and the return electrode; wherein the electrical polarity of the plurality of microneedle electrodes in the microneedle array is the same; In bipolar mode, the switch switching circuit is controlled to connect the power supply and the microneedle array; wherein the electrical polarity of at least one of the microneedle electrodes in the microneedle array is opposite to the electrical polarity of the remaining microneedle electrodes.

7. The radio frequency microneedle array control method according to claim 6, characterized in that: The radio frequency microneedle array control method further comprises: Controlling the microneedle array to switch between the monopolar mode and the bipolar mode at least once; When the microneedle array is controlled to work in a bipolar mode, the switch circuit is controlled to switch the electrodes of each microneedle electrode of the microneedle array.

8. The radio frequency microneedle array control method according to claim 6, characterized in that: The radio frequency microneedle array control method further comprises: Obtaining the impedance value of the tissue between the positive and negative electrodes of the microneedle electrode and a preset impedance threshold; The radio frequency energy output of the power supply is controlled according to the acquired impedance value of the tissue between the positive and negative electrodes of the microneedle electrode and a preset impedance threshold.

9. The radio frequency microneedle array control method according to claim 8, characterized in that: The step of obtaining the impedance value of the tissue between the positive and negative electrodes of the microneedle electrode and the preset impedance threshold specifically includes: After the microneedle electrode is inserted into the skin and reaches a preset depth, a current impedance value of the tissue between the positive and negative electrodes of the microneedle electrode is obtained; The preset impedance threshold is calculated based on the acquired current impedance value of the tissue between the positive and negative electrodes of the microneedle electrode.

10. The radio frequency microneedle array control method according to claim 8, characterized in that: The step of controlling the radio frequency energy output of the power supply according to the obtained impedance value of the tissue between the positive and negative electrodes of the microneedle and the preset impedance threshold specifically includes: When the impedance value of the tissue between the positive and negative electrodes of the microneedle continues to increase and is greater than the preset impedance threshold, the power supply is controlled to reduce the radio frequency energy output.

11. A radiofrequency microneedle therapeutic apparatus, characterized in that: It comprises the radio frequency microneedle array control device as described in any one of claims 1 to 5.

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