EPS composite acid for improving skin microbial barrier and preparation method of EPS composite acid

A technology for improving skin and microorganisms, which is applied in skin care preparations, pharmaceutical formulas, cosmetic preparations, etc. It can solve the problems of limited curative effect of photoaging skin, difficult control of exfoliation depth, and limited penetration depth, etc., to enhance skin barrier function Stable, good water retention and water retention ability, and the effect of maintaining the flora profile

CN114712263APending Publication Date: 2022-07-08绽妍生物科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2022-07-08

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Abstract

The invention provides EPS composite acid for improving skin microbial barrier and a preparation method thereof, and the EPS composite acid is prepared from the following raw materials in parts by weight: 12-25 parts of lactobacillus extracellular polysaccharide extract, 10-20 parts of salicylic acid, 8-12 parts of capryloyl salicylic acid, 2-8 parts of citric acid, 3-6 parts of lactic acid, 2-7 parts of mandelic acid, 5-10 parts of glycolic acid, 3-8 parts of aldose disaccharic acid, 2-5 parts of composite amino acid, 10-40 parts of dispersion liquid and 8-25 parts of emulsifier. Through mixing, scientific proportioning and synergistic effect of the compound acids, the skin barrier function can be recovered, the percutaneous moisture loss can be improved, the proportion of the compound amino acids can be adjusted, the skin can be protected, and the damage to the skin barrier can be reduced.
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Description

technical field

[0001] The invention relates to the technical field of cosmetics, in particular to an EPS composite acid for improving skin microbial barrier and a preparation method thereof. Background technique

[0002] The skin barrier is mainly composed of stratum corneum, structural lipids and skin lipid film, which protects various tissues and organs in the body from harmful external invasion and maintains the stability of the body's internal environment. Also included is the skin microbial barrier, which consists of the normal flora that colonizes the skin and mucosal surfaces. They can act as a barrier by competing with pathogens for binding epithelial cells and nutrients, or by secreting certain killing and bacteriostatic substances. The abnormal structure and function of the skin barrier are related to the etiology and pathological process of various skin diseases. Maintaining and repairing the skin barrier is of great significance to prevent bacterial invasion, r...

Examples

Embodiment 1

[0024] An EPS composite acid for improving skin microbial barrier comprises the following raw materials in parts by weight: 12 parts of lactobacillus exopolysaccharide extract, 10 parts of salicylic acid, 8 parts of octanoyl salicylic acid, 2 parts of citric acid, 3 parts of lactic acid, and mandelic acid 2 parts, 5 parts of glycolic acid, 3 parts of aldose acid, 2 parts of compound amino acid, 10 parts of dispersion liquid, 8 parts of emulsifier, the compound amino acid is composed of L-threonine with a mass ratio of 1:2:8 , histidine, D-methionine and hydroxyproline; the dispersion liquid is polycyanoacrylate n-butyl ester, and the emulsifier is PPG-26-butanol polyether-26.

Embodiment 2

[0026] An EPS composite acid for improving skin microbial barrier comprises the following raw materials in parts by weight: 25 parts of lactic acid bacteria exopolysaccharide extract, 20 parts of salicylic acid, 12 parts of octanoyl salicylic acid, 8 parts of citric acid, 6 parts of lactic acid, and mandelic acid 7 parts, 10 parts of glycolic acid, 8 parts of aldose acid, 5 parts of compound amino acid, 40 parts of dispersion liquid, 25 parts of emulsifier, the compound amino acid is composed of L-threonine with a mass ratio of 3:5:8 , histidine, D-methionine and hydroxyproline; the dispersion liquid is polycyanoacrylate n-butyl ester, and the emulsifier is PPG-26-butanol polyether-26.

Embodiment 3

[0028] An EPS composite acid for improving skin microbial barrier comprises the following raw materials in parts by weight: 20 parts of lactic acid bacteria exopolysaccharide extract, 15 parts of salicylic acid, 10 parts of octanoyl salicylic acid, 6 parts of citric acid, 4 parts of lactic acid, and mandelic acid 5 parts, 8 parts of glycolic acid, 5 parts of aldose acid, 3 parts of compound amino acid, 25 parts of dispersion liquid, 15 parts of emulsifier, the compound amino acid is composed of L-threonine with a mass ratio of 2:3:8 , histidine, D-methionine, hydroxyproline; the dispersion liquid is polycyanoacrylate n-butyl ester, and the emulsifier is PPG-26-butanol polyether-26;