A piperacillin sodium injection filtering device

Abstract

The present invention discloses a piperacillin sodium injection filtering device, which relates to the technical field of drug preparation; comprising: a filtering tank body, wherein a filter press chamber, a liquid collecting chamber and a filter out chamber are arranged inside the filtering tank body, wherein the filter press chamber is located above the liquid collecting chamber and is connected with the liquid collecting chamber, and the upper end of the liquid collecting chamber is connected with the filter out chamber; a first sealing pair of rollers, wherein the roller body is a flexible material, and is located on one side of the width direction of the lower end of the filter press chamber; a second sealing pair of rollers, wherein the roller body is a flexible material, and is located on the other side of the width direction of the lower end of the filter press chamber; a driving roller, which is located at the upper end of the filter out chamber; a filter belt, which is sequentially stretched on the second sealing pair of rollers, the first sealing pair of rollers and the driving roller; wherein the filter press chamber and the liquid collecting chamber are separated by the filter belt. The present invention can ensure that the filter belt is always in a state of high-efficiency filtration, greatly reduce the frequency of cleaning the filter belt, and thus improve the production efficiency of piperacillin sodium injection.

Description

Technical Field

[0001] The invention relates to the technical field of drug preparation, and in particular to a piperacillin sodium filtering device for injection. Background Art

[0002] Piperacillin sodium is a broad-spectrum semi-synthetic β-lactam antibiotic that exerts a bactericidal effect by inhibiting the bacterial cell wall. It has certain antibacterial activity against many Gram-positive bacteria, Gram-negative bacteria and some anaerobic bacteria. In the existing technology, in order to ensure that the active ingredients of piperacillin sodium remain active, most of the piperacillin sodium for injection are produced using a freeze-drying manufacturing process. The main steps are dissolving the raw material, and then vacuum drying it in a low-temperature (30-45°C) vacuum environment after multiple filtrations.

[0003] Among them, the filtrate after impurity removal filtration is crystallized under low temperature (0-10°C) environment, and then two-stage filtration (0.45μm and 0.22μm) is performed to obtain the filter cake. Since the filtration accuracy of the final filtration is relatively high, filter pressing is usually used to improve the filtration efficiency. However, as the filtration proceeds, the drug crystals precipitate on the surface of the filter component, making it difficult for the filtrate to flow smoothly and the filtration pressure increases. In order to ensure that the filter component can filter normally and some crystals pass through the filter component, the filter component needs to be cleaned in time, resulting in low filtration efficiency and affecting the production efficiency of piperacillin sodium for injection. Summary of the invention

[0004] Aiming at the technical problem that the existing filter for filtering piperacillin sodium for injection has low filtration efficiency; the present invention provides a piperacillin sodium for injection filtering device, wherein a circulating filter belt is arranged at the lower end of a filter chamber, and filtered piperacillin sodium crystals are pressed into blocks by a first sealing roller pair, and the blocks are automatically dropped at the turning point of the filter belt, so that the filter belt recovers the flow capacity, ensures that the filter belt can filter normally and improves the filtration efficiency, avoids excessive filtration pressure causing some strains to pass through the filter belt, can greatly reduce the frequency of cleaning the filter belt, and thus improves the production efficiency of piperacillin sodium for injection.

[0005] The present invention is achieved through the following technical solutions:

[0006] The present invention provides a piperacillin sodium injection filtering device, comprising: a filtering tank body, wherein a filter pressure chamber, a liquid collecting chamber and a filtration chamber are arranged inside the filtering tank body, wherein the filter pressure chamber is located above the liquid collecting chamber and is communicated with the liquid collecting chamber, and the upper end of the liquid collecting chamber is communicated with the filtration chamber; a first sealing pair of rollers, wherein the roller body is made of a flexible material and is located on one side of the lower end of the filter pressure chamber in the width direction; a second sealing pair of rollers, wherein the roller body is made of a flexible material and is located on the other side of the lower end of the filter pressure chamber in the width direction; a driving roller, which is located at the upper end of the filtration chamber; and a filter belt, which is sequentially stretched on the second sealing pair of rollers, the first sealing pair of rollers and the driving roller; wherein the filter pressure chamber and the liquid collecting chamber are separated by the filter belt.

[0007] The piperacillin sodium injection filtering device provided by the present invention comprises a filter press chamber, a liquid collecting chamber and a filtration chamber arranged in a filtering tank body, the filter press chamber is located above the liquid collecting chamber and is communicated with the liquid collecting chamber, the upper end of the liquid collecting chamber is communicated with the filtration chamber, a first sealing pair of rollers and a second sealing pair of rollers are arranged on both sides of the width direction of the lower end of the filter press chamber, the first sealing pair of rollers and the second sealing pair of rollers are used to seal the gap between the filter belt and the lower end of the filter press chamber, so that the filter belt separates the filter press chamber and the liquid collecting chamber; at the same time, the filter belt is stretched above the filtration chamber by a driving roller, so that the filter belt can move back and forth between the filter press chamber and the liquid collecting chamber and the filtration chamber.

[0008] When in use, the piperacillin sodium solution for injection to be filtered is introduced into the filter press cavity, and the solution in the filter press cavity is pressurized so that the solution is filtered through the filter belt, and the filtered liquid directly enters the liquid collecting cavity for collection or centralized discharge, and the drug crystals are retained on the filter belt. At this time, the filter belt is driven by the driving roller to move from the second sealing roller to the first sealing roller and the driving roller in sequence, and the drug crystals retained on the filter belt are squeezed by the first sealing roller, and the liquid carried by the drug crystals is pressed out and retained in the filter press cavity, and pressed into blocks, and then driven by the filter belt to enter the top of the filtration cavity.

[0009] As the driving roller continues to rotate, when the part of the filter belt carrying the block drug crystals moves to the driving roller, the filter belt bypasses the driving roller and flips 180°. Due to poor flexibility, the block drug crystals break away from the filter belt during the bending process of the filter belt and fall into the filter chamber under the action of gravity, thereby collecting the drug filter cake through the filter chamber. After the block drug cake falls, the filter belt resumes its filtering capacity. When the filter belt moves toward the driving roller, the part of the filter belt that does not filter the drug crystals moves to the bottom of the filter press chamber for filtering, which can quickly filter.

[0010] In summary, the piperacillin sodium injection filtration device provided by the present invention can ensure that the filter belt is always in a state of high-efficiency filtration, ensure that the filter belt can filter normally and improve the filtration efficiency, avoid excessive filtration pressure causing some strains to pass through the filter belt, and can greatly reduce the frequency of cleaning the filter belt, thereby improving the production efficiency of piperacillin sodium injection.

[0011] In an optional embodiment, an eccentric rapping member is provided in the filter chamber, and the eccentric rapping member is located on one side of the moving path of the filter belt; wherein, when the eccentric rapping member rotates, one end of the eccentric rapping member can abut against the filter belt, so as to prevent bulk drugs from remaining on the filter belt by rapping the filter belt with the eccentric rapping member.

[0012] In an optional embodiment, a section of the eccentric rapping member is provided with a spherical rapping portion, and the rapping portion is used to rap the filter belt to prevent the eccentric rapping member from damaging the filter belt when rapping the filter belt.

[0013] In an optional embodiment, a cleaning chamber is further provided in the filter tank body, and the cleaning chamber is used to hold an acetone solution; the cleaning chamber is located between the liquid collecting chamber and the filtration chamber, and the filter belt passes through the cleaning chamber to clean the drug crystals remaining on the filter belt with acetone, thereby ensuring that the filter belt can restore its filtering capacity.

[0014] In an optional embodiment, two supporting rollers are provided in the filter tank body, and along the length direction of the filter belt, the two supporting rollers are arranged on both sides of the upper end of the cleaning chamber; a limiting roller is provided in the cleaning chamber, and the filter belt is stretched on the supporting roller and the limiting roller, so that the filter belt passes through the inner cavity of the cleaning chamber when it moves in a circulation through the joint action of the two supporting rollers and the limiting roller.

[0015] In an optional embodiment, an acetone nozzle is further provided in the filter tank body, and the acetone nozzle is located above the limiting roller, and the acetone nozzle is facing the bottom or side wall of the cleaning chamber, so that acetone can be sprayed toward the filter belt through the acetone nozzle to strongly clean the filter belt, thereby ensuring that the filter belt can fully restore its filtering capacity.

[0016] In an optional embodiment, it also includes a piston cylinder, the inner cavity of the piston cylinder is divided into a pressure-sensitive chamber and a storage chamber by a piston body, and the pressure-sensitive chamber is communicated with the filter press chamber; the storage chamber is used to store acetone, and the storage chamber is connected to the acetone nozzle; a return spring is also arranged in the piston cylinder, and the return spring stores energy when the piston body compresses the acetone.

[0017] Since the pressure sensing chamber is connected to the filter press chamber, one side of the piston body is the pressure in the filter press chamber. As the flow capacity of the filter belt filtrate decreases, the pressure in the filter press chamber increases. As the pressure in the filter press chamber increases, the acetone in the storage chamber is squeezed, thereby pressurizing the acetone, so that the acetone can be sprayed out at a certain pressure to ensure the cleaning effect of acetone on the filter belt. After the filter belt is cleaned by acetone, the flow capacity of the filter belt filtrate is restored, the pressure in the filter press chamber is reduced, and the piston body is reset under the action of the reset spring.

[0018] In an optional embodiment, a back pressure valve is provided between the storage chamber and the acetone nozzle, so that the acetone in the storage chamber is sprayed out according to a set pressure, and can also act as a safety valve to avoid excessive pressure in the filter press chamber.

[0019] In an optional embodiment, flexible sealing strips are provided on both sides of the filter belt in the length direction, and the flexible sealing strips are used to seal the gap between the two sides of the filter belt in the length direction and the filter press cavity to ensure the sealing between the filter belt and the filter press cavity.

[0020] In an optional embodiment, the flexible sealing strip is a hollow rubber strip to ensure that the flexible sealing strip has sufficient deformation.

[0021] Compared with the prior art, the present invention has the following advantages and beneficial effects

[0022] 1. The piperacillin sodium injection filtering device provided by the present invention comprises a filter press chamber, a liquid collecting chamber and a filtration chamber arranged in a filtering tank body, the filter press chamber is located above the liquid collecting chamber and is communicated with the liquid collecting chamber, the upper end of the liquid collecting chamber is communicated with the filtration chamber, a first sealing pair of rollers and a second sealing pair of rollers are arranged on both sides of the width direction of the lower end of the filter press chamber, the first sealing pair of rollers and the second sealing pair of rollers seal the gap between the filter belt and the lower end of the filter press chamber, so that the filter belt separates the filter press chamber and the liquid collecting chamber; at the same time, the filter belt is stretched above the filtration chamber by a driving roller, so that the filter belt can be The filter chamber, the liquid collecting chamber and the filter chamber move back and forth in a circular motion. The drug crystals trapped on the filter belt are squeezed by the first sealing roller, and the liquid carried by the drug crystals is pressed out and trapped in the filter press chamber, and is pressed into blocks. The blocks are separated from the filter belt during the bending process of the filter belt. Therefore, it can ensure that the filter belt is always in a state of high-efficiency filtration, ensure that the filter belt can filter normally and improve the filtration efficiency, avoid excessive filtration pressure that causes some strains to pass through the filter belt, and can greatly reduce the frequency of cleaning the filter belt, thereby improving the production efficiency of piperacillin sodium for injection.

[0023] 2. The piperacillin sodium injection filtering device provided by the present invention detaches from the filter belt during the bending process of the filter belt and falls into the filtration chamber under the action of gravity, which is convenient for collecting the filtered drugs. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0025] In the attached picture:

[0026] Figure 1 This is a schematic diagram of the structure of a piperacillin sodium injection filtration device according to an embodiment of the present invention;

[0027] Figure 2 is a schematic cross-sectional view of a filter belt according to an embodiment of the present invention;

[0028] Figure 3 This is a schematic structural diagram of a piston cylinder according to an embodiment of the present invention;

[0029] Figure 4 Schematic diagram of the pipeline principle of an embodiment of the present invention.

[0030] Marks and corresponding parts names in the attached drawings:

[0031] 10-filter tank, 11-filter pressure chamber, 12-liquid collecting chamber, 13-filtering chamber, 14-cleaning chamber, 15-supporting roller, 16-limiting roller, 17-acetone nozzle;

[0032] 20-first sealing roller pair;

[0033] 30- second sealing roller;

[0034] 40- driving roller;

[0035] 50-filter belt, 51-flexible sealing strip;

[0036] 60-eccentric rapping member, 61-rapping portion;

[0037] 70 - piston cylinder, 71 - piston body, 72 - pressure sensing chamber, 73 - storage chamber, 74 - return spring, 75 - back pressure valve. DETAILED DESCRIPTION

[0038] In order to make the purpose, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below in combination with the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments.

[0039] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, further definition and explanation thereof is not required in subsequent drawings.

[0040] In the description of the embodiments of the present application, the terms "center", "up", "down", "left", "right", "vertical", "longitudinal", "lateral", "horizontal", "inside", "outside", "front", "back", "top", "bottom", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, or are the orientations or positional relationships in which the products of the application are conventionally placed when in use, or are the orientations or positional relationships conventionally understood by those skilled in the art. They are merely for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0041] Example 1

[0042] Combination Figure 1 The present embodiment provides a piperacillin sodium injection filtering device, comprising: a filtering tank body 10, wherein a filter press chamber 11, a liquid collecting chamber 12 and a filtration chamber 13 are arranged inside the filtering tank body 10, wherein the filter press chamber 11 is located above the liquid collecting chamber 12 and is communicated with the liquid collecting chamber 12, and the upper end of the liquid collecting chamber 12 is communicated with the filtration chamber 13; a first sealing pair of rollers 20, wherein the roller body is made of a flexible material and is located on one side of the lower end of the filter press chamber 11 in the width direction; a second sealing pair of rollers 30, wherein the roller body is made of a flexible material and is located on the other side of the lower end of the filter press chamber 11 in the width direction; a driving roller 40, which is located at the upper end of the filtration chamber 13; a filtering belt 50, which is sequentially stretched on the second sealing pair of rollers 30, the first sealing pair of rollers 20 and the driving roller 40; wherein the filter press chamber 11 and the liquid collecting chamber 12 are separated by the filtering belt 50.

[0043] Specifically, since the crystallization temperature of piperacillin sodium for injection is relatively low, in order to avoid the re-dissolution of the precipitated crystals, it is necessary to ensure that the solution maintains a relatively low temperature during the filtration process. Therefore, a heat preservation layer is usually provided on the side wall of the filter press chamber 11 to reduce the heat exchange between the piperacillin sodium solution and the environment. In order to reduce the input of exogenous heat during the filter press process, the filter press is usually performed by gas pressurization.

[0044] In order to ensure that the first sealing roller 20 and the second sealing roller 30 can seal the part where the filter belt 50 intersects with the lower end of the filter press chamber 11, the filter press chamber 11 is usually processed into a rectangular shape. For the first sealing roller 20 and the second sealing roller 30, the length of the flexible section should be greater than the width of the lower end of the filter press chamber 11, and at the same time, one side of the flexible section of the first sealing roller 20 and the second sealing roller 30 is tightly against the end of the lower end of the filter press chamber 11, and the other side is pressed against the upper surface of the filter belt 50.

[0045] Combination Figure 2 Flexible sealing strips 51 are provided on both sides of the filter belt 50 in the length direction. The flexible sealing strips 51 are used to seal the gap between the two sides of the filter belt 50 in the length direction and the filter press cavity 11 to ensure the sealing between the filter belt 50 and the filter press cavity 11.

[0046] Preferably, the flexible sealing strip 51 is a hollow rubber strip to ensure that the flexible sealing strip 51 has sufficient deformation.

[0047] In summary, the piperacillin sodium injection filtration device provided in this embodiment is provided with a filter press chamber 11, a liquid collecting chamber 12 and a filtration chamber 13 in a filtration tank body 10, the filter press chamber 11 is located above the liquid collecting chamber 12 and is connected with the liquid collecting chamber 12, the upper end of the liquid collecting chamber 12 is connected with the filtration chamber 13, and a first sealing pair of rollers 20 and a second sealing pair of rollers 30 are provided on both sides of the width direction of the lower end of the filter press chamber 11, and the gap between the filter belt 50 and the lower end of the filter press chamber 11 is sealed by the first sealing pair of rollers 20 and the second sealing pair of rollers 30, so that the filter press chamber 11 and the liquid collecting chamber 12 are separated by the filter belt 50; at the same time, the filter belt 50 is stretched above the filtration chamber 13 by the driving roller 40, so that the filter belt 50 can move back and forth between the filter press chamber 11 and the liquid collecting chamber 12 and the filtration chamber 13.

[0048] When in use, the piperacillin sodium solution for injection to be filtered is introduced into the filter press chamber 11, and the solution in the filter press chamber 11 is pressurized so that the solution is filtered through the filter belt 50, and the filtered liquid directly enters the liquid collecting chamber 12 for collection or centralized discharge, and the drug crystals are retained on the filter belt 50. At this time, the filter belt 50 is driven by the driving roller 40 to move from the second sealing roller pair 30 to the first sealing roller pair 20 and the driving roller 40 in sequence. Under the pressure of the first sealing roller pair 20, the drug crystals retained on the filter belt 50 press out the liquid carried by the drug crystals and retain them in the filter press chamber 11, and are pressed into blocks, and then driven by the filter belt 50 to enter the upper part of the filtration chamber 13.

[0049] As the driving roller 40 continues to rotate, when the portion of the filter belt 50 carrying the bulk drug crystals moves to the driving roller 40, the filter belt 50 bypasses the driving roller 40 and flips 180°. Due to poor flexibility, the bulk drug crystals break away from the filter belt 50 during the bending process of the filter belt 50 and fall into the filter chamber 13 under the action of gravity, thereby collecting the drug filter cake through the filter chamber 13. After the bulk drug cake falls, the filter belt 50 resumes its filtering capacity. When the filter belt 50 moves toward the driving roller 40, the portion of the filter belt 50 that does not filter the drug crystals moves to the bottom of the filter press chamber 11 for filtering, and filtering can be performed quickly.

[0050] In summary, the piperacillin sodium injection filtration device provided in this embodiment can ensure that the filter belt 50 is always in a state of high-efficiency filtration, ensure that the filter belt 50 can filter normally and improve the filtration efficiency, avoid excessive filtration pressure causing some strains to pass through the filter belt 50, and can greatly reduce the frequency of cleaning the filter belt 50, thereby improving the production efficiency of piperacillin sodium injection.

[0051] Example 2

[0052] Combination Figure 1 This embodiment provides a piperacillin sodium injection filtering device. Based on the structure and principle described in Embodiment 1, an eccentric rapping member 60 is provided in the filtration chamber 13. The eccentric rapping member 60 is located on one side of the moving path of the filter belt 50. When the eccentric rapping member 60 rotates, one end of the eccentric rapping member 60 can contact the filter belt 50. When the overall filtering capacity of the filter belt 50 decreases, the filter belt 50 is rapped by the eccentric rapping member 60 to prevent bulk drugs from remaining on the filter belt 50.

[0053] Preferably, a spherical rapping portion 61 is provided at one section of the eccentric rapping member 60 , and the rapping portion 61 is used to rap the filter belt 50 to prevent the eccentric rapping member 60 from damaging the filter belt 50 when rapping the filter belt 50 .

[0054] Example 3

[0055] Combination Figure 1 The present embodiment provides a piperacillin sodium injection filtering device. Based on the structure and principle described in Embodiment 1 or 2, a cleaning chamber 14 is further provided in the filtering tank body 10, and the cleaning chamber 14 is used to contain the acetone solution; the cleaning chamber 14 is located between the liquid collecting chamber 12 and the filtration chamber 13, and the filter belt 50 passes through the cleaning chamber 14 to clean the drug crystals remaining on the filter belt 50 with acetone, thereby ensuring that the filter belt 50 can restore its filtering capacity.

[0056] In this embodiment, two support rollers 15 are provided in the filter tank body 10, and along the length direction of the filter belt 50, the two support rollers 15 are arranged on both sides of the upper end of the cleaning chamber 14; a limiting roller 16 is provided in the cleaning chamber 14, and the filter belt 50 is stretched on the support roller 15 and the limiting roller 16, so that the filter belt 50 passes through the inner cavity of the cleaning chamber 14 when it moves in a circulation through the joint action of the two support rollers 15 and the limiting roller 16.

[0057] On this basis, an acetone nozzle 17 is further provided in the filter tank body 10, and the acetone nozzle 17 is located above the limiting roller 16, and the acetone nozzle 17 is facing the bottom or side wall of the cleaning chamber 14, so that acetone can be sprayed toward the filter belt 50 through the acetone nozzle 17 to strongly clean the filter belt 50, thereby ensuring that the filter belt 50 can fully restore its filtering capacity.

[0058] In addition, combined Figure 3 In this embodiment, it also includes a piston cylinder 70, the inner cavity of the piston cylinder 70 is divided into a pressure-sensing chamber 72 and a storage chamber 73 by a piston body 71, the pressure-sensing chamber 72 is communicated with the filter press chamber 11; the storage chamber 73 is used to store acetone, and the storage chamber 73 is connected to the acetone nozzle 17; a return spring 74 is also provided in the piston cylinder 70, and the return spring 74 stores energy when the piston body 71 compresses the acetone.

[0059] Since the pressure sensing chamber 72 is connected to the filter press chamber 11, the pressure in the filter press chamber 11 is on one side of the piston body 71. As the filtrate flow capacity of the filter belt 50 decreases, the pressure in the filter press chamber increases. As the pressure in the filter press chamber 11 increases, the acetone in the storage chamber 73 is squeezed, thereby pressurizing the acetone, so that the acetone can be sprayed out at a certain pressure, ensuring the cleaning effect of the acetone on the filter belt 50. After the filter belt 50 is cleaned by acetone, the filtrate flow capacity of the filter belt 50 is restored, the pressure in the filter press chamber 11 is reduced, and the piston body 71 is reset under the action of the reset spring 74.

[0060] The piston body 71 is pushed by the medium in the filter press chamber 11 to pressurize the acetone, and no external booster pump is required. A pressure detection element and a control system are also required, which can simplify the structure of the device and improve the reliability of the device. The acetone in the storage chamber 73 can be added regularly, or the height of the acetone liquid level in the cleaning chamber 14 can be increased, so that the acetone nozzle 17 can penetrate below the acetone liquid level and suck a corresponding amount of acetone while the piston body 71 is reset.

[0061] On this basis, combined with Figure 4 A back pressure valve 75 is provided between the storage chamber 73 and the acetone nozzle 17 so that the acetone in the storage chamber 73 can be sprayed out according to a set pressure and can also act as a safety valve to prevent excessive pressure in the filter press chamber 11.

[0062] The specific implementation methods described above further illustrate the objectives, technical solutions and beneficial effects of the present invention in detail. It should be understood that the above description is only a specific implementation method of the present invention and is not intended to limit the scope of protection of the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A piperacillin sodium injection filtering device, characterized in that: include: A filter tank body (10), wherein a filter pressure chamber (11), a liquid collecting chamber (12) and a filter out chamber (13) are arranged inside the filter tank body (10), the filter pressure chamber (11) is located above the liquid collecting chamber (12) and is in communication with the liquid collecting chamber (12), and the upper end of the liquid collecting chamber (12) is in communication with the filter out chamber (13); A first sealing pair of rollers (20), the roller body of which is made of a flexible material and is located on one side of the lower end of the filter press chamber (11) in the width direction; A second sealing roller pair (30), the roller body of which is made of a flexible material and is located on the other side of the lower end of the filter press chamber (11) in the width direction; A driving roller (40) located at the upper end of the filtration chamber (13); A filter belt (50) is sequentially stretched on the second sealing roller pair (30), the first sealing roller pair (20) and the driving roller (40); Wherein, the filter press chamber (11) and the liquid collecting chamber (12) are separated by the filter belt (50); A cleaning chamber (14) is also provided in the filtering tank body (10), and the cleaning chamber (14) is used to contain an acetone solution; The cleaning chamber (14) is located between the liquid collecting chamber (12) and the filtering chamber (13), and the filter belt (50) passes through the cleaning chamber (14); Two support rollers (15) are arranged in the filter tank (10), and along the length direction of the filter belt (50), the two support rollers (15) are arranged on both sides of the upper end of the cleaning chamber (14); A limiting roller (16) is arranged in the cleaning chamber (14), and the filter belt (50) is stretched on the supporting roller (15) and the limiting roller (16); An acetone nozzle (17) is also provided in the filter tank (10), the acetone nozzle (17) is located above the limiting roller (16), and the acetone nozzle (17) faces the bottom or side wall of the cleaning chamber (14); It also comprises a piston cylinder (70), the inner cavity of the piston cylinder (70) being divided into a pressure sensing cavity (72) and a storage cavity (73) by a piston body (71), and the pressure sensing cavity (72) is in communication with the filter pressure cavity (11); The storage chamber (73) is used to store acetone, and the storage chamber (73) is connected to the acetone nozzle (17); A return spring (74) is also provided in the piston cylinder (70), and the return spring (74) stores energy when the piston body (71) compresses acetone.

2. The piperacillin sodium for injection filtration device according to claim 1, characterized in that: An eccentric rapping member (60) is disposed in the filter cavity (13), and the eccentric rapping member (60) is located on one side of the moving path of the filter belt (50); Wherein, when the eccentric rapping member (60) is rotating, one end thereof can abut against the filter belt (50).

3. The piperacillin sodium for injection filtration device according to claim 2, characterized in that: A spherical rapping portion (61) is provided at one section of the eccentric rapping member (60), and the rapping portion (61) is used to rap the filter belt (50).

4. The piperacillin sodium injection filtration device according to claim 1, characterized in that: A back pressure valve (75) is provided between the storage chamber (73) and the acetone nozzle (17).

5. The piperacillin sodium injection filtration device according to any one of claims 1 to 4, characterized in that: Flexible sealing strips (51) are provided on both sides of the filter belt (50) in the length direction, and the flexible sealing strips (51) are used to seal the gap between the two sides of the filter belt (50) in the length direction and the filter press cavity (11).

6. The piperacillin sodium injection filtration device according to claim 5, characterized in that: The flexible sealing strip (51) is a hollow rubber strip.

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