Collision cell device and implementation method
The detachable design and the metal collision cell device solve the problem of low assembly efficiency in the prior art, realize an easy-to-assemble and high-precision collision cell device, and improve the performance and reliability of the mass spectrometer.
Patent Information
- Application Number
- CN202411084580.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-08
- Publication Date
- 2025-09-12
- Estimated Expiration
- 2044-08-08
AI Technical Summary
In the prior art, the collision cell adopts a one-time non-detachable design, which has high assembly process requirements, low efficiency, high scrap rate, and is difficult to meet actual production needs.
A detachable collision cell device is provided, comprising a metal cell body, a multipole fixing part, a multipole, a terminal post and an electron lens. The device is assembled in a detachable manner, using metal materials and precision processing technology, combined with a digital model to optimize component positions and installation processes.
The invention realizes easy assembly and good precision consistency, reduces working hours, improves equipment performance and reliability, and solves the problem of low assembly efficiency in the prior art.
Smart Images

Figure CN118866647B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of collision cell assembly, and in particular to a collision cell device and an implementation method thereof. Background Art
[0002] Mass spectrometry is one of the most important methods in the field of analysis. With the development of science and technology, mass spectrometry not only occupies an important position in routine chemical analysis, but has also gradually become one of the main methods in popular fields such as life sciences, homeland security, food safety, clinical medical testing and space technology.
[0003] A mass spectrometer typically consists of a sample introduction system, an ion source, an ion optics system, a mass analyzer, a detector, a data acquisition and control system, and a vacuum system. The collision reaction cell, typically located between the ion optics system and the mass analyzer, is a crucial component for removing polyatomic ion interference. Mass spectrometer analysis is primarily affected by mass spectral interference and non-mass spectral interference, primarily isobaric polyatomic ions, refractory oxides, doubly charged ions, and background mass spectra. The collision cell plays a key role in suppressing mass spectral interference.
[0004] The collision cell currently used in AB SCIEX mass spectrometers is constructed from a ceramic cell body containing a multipole rod. Ion inlet and outlet holes are located at both ends of the cell body, and holes are provided in the barrel wall for the inlet and outlet of collision or reaction gases. The cell body is filled with collision or reaction gas and maintained at a pressure slightly higher than that of the surrounding vacuum chamber. The cell body is secured to the multipole rods and ion lens using adhesive bonding.
[0005] The disadvantages of this structure are that it requires high assembly process, it is difficult to ensure precision, and it requires special high-precision tooling; it is assembled once and cannot be disassembled, resulting in a high scrap rate; the assembly time is long and the efficiency is low. It cannot meet the needs of actual production. Summary of the Invention
[0006] The purpose of the present invention is to provide a collision cell device and an implementation method, aiming to solve the problem that the collision cell in the prior art adopts a one-time assembly design, has high assembly process requirements and is inefficient.
[0007] The present invention is implemented as follows: In a first aspect, the present invention provides a collision cell device, comprising:
[0008] A tank body and two port structures, wherein the two port structures are detachably arranged at both ends of the tank body;
[0009] The cell body includes a metal cell body, a plurality of multipole fixing parts, a plurality of multipole rods and a plurality of terminal posts;
[0010] The metal cell body has a cavity structure inside, and the plurality of multipole rod fixing members are respectively arranged at both ends of the cavity structure of the metal cell body, and the ends of the plurality of multipole rods are respectively fixed to the multipole rod fixing members arranged at both ends of the cavity structure of the metal cell body, thereby being arranged in the cavity structure of the metal cell body;
[0011] A plurality of openings are provided on the inner wall of the cavity structure of the metal cell body, and a plurality of the terminal posts are respectively arranged in the plurality of openings through sealing rings, and the plurality of the terminal posts are fixedly connected to the multipole;
[0012] The port structure includes a short rod assembly and an electron lens;
[0013] The short rod assembly is fixed at both ends of the cavity structure of the metal pool body by screws;
[0014] The electron lens is arranged in the inner cavity of the short rod assembly. When the short rod assembly is fixedly arranged at both ends of the cavity structure of the metal pool body, the electron lens is set in the multipole fixing member through a sealing ring. At this time, the electron lens is in the cavity structure of the metal pool body.
[0015] Preferably, a sealing insulator is further provided on the sealing ring of the terminal sleeve to perform double-layer sealing treatment on the terminal.
[0016] In a second aspect, the present invention provides a method for implementing a collision cell device, which is used to manufacture the collision cell device described in the first aspect, comprising:
[0017] A metal pool body with a cavity structure is obtained by processing metal materials;
[0018] Performing a hole-opening operation on the cavity wall of the cavity structure of the metal pool body to produce a plurality of holes on the cavity wall of the cavity structure of the metal pool body;
[0019] Installing a plurality of multipole fixing members at both ends of the cavity structure of the metal cell body;
[0020] respectively fixing the ends of the plurality of multipole rods to the plurality of multipole rod fixing members installed at the two ends of the cavity structure of the metal cell body, thereby arranging the plurality of multipole rods inside the cavity structure of the metal cell body;
[0021] Sleeving sealing rings on a plurality of terminal posts, and installing the plurality of terminal posts with sealing rings on the cavity wall of the cavity structure of the metal cell body through the plurality of openings, and performing a fixed connection process on the terminal posts and the multipole rods;
[0022] Installing the electron lens in the inner cavity of the short rod assembly and sleeve a sealing ring on the electron lens;
[0023] The short rod assembly is installed at both ends of the cavity structure of the metal pool body, and the short rod assembly and the metal pool body are fixedly connected by screws.
[0024] Preferably, before manufacturing the metal pool body, the metal pool body is analyzed in advance to obtain a pool body planning scheme; wherein the pool body planning scheme is used to guide subsequent manufacturing steps.
[0025] Preferably, the step of analyzing the metal pool body in advance to obtain a pool body planning scheme includes:
[0026] Acquiring specification information of the metal cell body, and constructing a cell body digital model for performing digital feedback on the metal cell body according to the specification information of the metal cell body;
[0027] Performing position simulation processing of the terminal and the multipole based on the digital model of the cell body to obtain theoretical position information of the terminal and the multipole in the digital model of the cell body;
[0028] Performing position deduction processing on the opening according to the theoretical position information of the terminal in the digital model of the cell body to obtain the theoretical position information of the opening in the digital model of the cell body;
[0029] Performing position deduction processing on the multipole fixing member according to theoretical position information of the multipole in the digital model of the cell body to obtain theoretical position information of the multipole fixing member in the digital model of the cell body;
[0030] The theoretical position information of the terminal, the multipole, the opening, and the multipole fixing member in the digital model of the cell body is used together as the cell body planning scheme.
[0031] Preferably, the step of performing position simulation processing on the terminal and the multipole based on the digital model of the cell body to obtain theoretical position information of the terminal and the multipole in the digital model of the cell body includes:
[0032] Acquiring specification information of the terminal and the multipole, and constructing a corresponding digital model of the terminal according to the specification information of the terminal, and constructing a corresponding digital model of the multipole according to the specification information of the multipole;
[0033] Planning the arrangement of the terminal and the multipole based on the cell body digital model to obtain arrangement constraints of the terminal and the multipole;
[0034] According to the setting restriction conditions of the terminal and the multipole, a position setting simulation processing of the digital model of the terminal and the multipole is performed on the basis of the digital model of the cell body to obtain several simulated setting positions of the terminal and the multipole;
[0035] Performing position adaptability analysis on the plurality of simulated setting positions of the terminal and the multipole to obtain position adaptability between the terminal and the plurality of simulated setting positions of the multipole;
[0036] The simulated setting positions of the binding posts and the multipole rods having the best position adaptability are used as theoretical position information of the binding posts and the multipole rods in the digital model of the cell body.
[0037] The present invention provides a method for implementing a collision cell device, which has the following beneficial effects:
[0038] The present invention provides a collision cell with a detachable design, comprising a cell body and two port structures, wherein the two port structures are detachably arranged at both ends of the cell body. Due to the detachable installation method, assembly is easy, working hours are reduced, and precision consistency is good. At the same time, due to the use of a metal cell body, the shielding effect is good, which is conducive to improving equipment performance, and solves the problem of a one-time assembly design of the collision cell in the prior art, which has high assembly process requirements and low efficiency.
[0039] At the same time, since the multipole is pre-positioned and installed with a multipole fixture, the accuracy of the multipole setting can be ensured, and the terminal adopts a double-layer sealing structure to enhance the sealing performance. BRIEF DESCRIPTION OF THE DRAWINGS
[0040] Figure 1 1 is a schematic structural diagram of a collision cell device provided by an embodiment of the present invention;
[0041] Figure 2 It is a schematic diagram of the steps of a method for implementing a collision cell device provided by an embodiment of the present invention.
[0042] Figure numerals: 1 - cell body, 2 - port structure, 11 - metal cell body, 12 - multipole fixing member, 13 - multipole, 14 - terminal, 21 - electron lens, 22 - short rod assembly, 3 - sealing ring, 4 - sealing insulator. DETAILED DESCRIPTION
[0043] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.
[0044] The implementation of the present invention is described in detail below with reference to specific embodiments.
[0045] Reference Figure 1 、 Figure 2 As shown, a preferred embodiment of the present invention is provided.
[0046] In a first aspect, the present invention provides a collision cell device, comprising:
[0047] The pool body 1 and two port structures 2 are detachably arranged at both ends of the pool body 1.
[0048] Specifically, in the traditional design of collision cell devices, a disposable, non-detachable design is usually adopted, resulting in a high scrap rate. However, in an embodiment provided by the present invention, the collision cell device is designed as a detachable assembly process, which reduces the assembly difficulty and improves the assembly efficiency and assembly yield.
[0049] More specifically, the cell body 1 includes a metal cell body 11, a plurality of multipole fixing parts 12, a plurality of multipole rods 13 and a plurality of terminal posts 14; in traditional designs, the cell body is usually made of ceramic. In the embodiment provided by the present invention, metal material is selected to manufacture the cell body, which reduces the processing difficulty and improves the processing efficiency and processing yield.
[0050] More specifically, the metal pool body 11 has a cavity structure inside, and several multipole fixing parts 12 are respectively arranged at both ends of the cavity structure of the metal pool body 11, and the two ends of several multipoles 13 are respectively fixed on the multipole fixing parts 12 arranged at both ends of the cavity structure of the metal pool body 11, thereby being arranged in the cavity structure of the metal pool body 11.
[0051] It should be noted that a cavity structure is processed inside the metal pool body 11 to reserve a reaction space for the collision function of the collision pool. At the same time, the remaining components also need to be arranged inside the cavity structure of the metal pool body 11.
[0052] More specifically, the multipole 13 functions as ion guidance and focusing, as well as collision-induced dissociation (CID). By applying alternating direct current (DC) and radio frequency (RF) voltages, the multipole 13 creates a stable electric field. This field effectively guides and focuses ions, causing them to move along the central axis, preventing ion scattering and loss. The design of the multipole 13 focuses ions into the central region as they pass through, improving ion transmission efficiency and ensuring that more ions can pass through the collision cell and enter the mass analyzer. The electric field in the multipole 13 controls the kinetic energy of the ions, ensuring that they have the appropriate energy when colliding with the collision gas molecules, enabling efficient collision-induced dissociation (CID). By adjusting the voltage on the multipole 13, the degree of ion fragmentation can be controlled, generating specific fragment ions and providing more structural information. The multipole 13 also acts as a mass filter, allowing only ions with a specific mass-to-charge ratio (m / z) to pass through by adjusting the voltage and frequency. This is particularly important in multistage mass spectrometry (MS / MS) analysis, enabling the selective transmission of target ions.
[0053] It should be noted that in the embodiment provided by the present invention, the multipole 13 is fixedly installed using a multipole fixing member 12, and the multipole fixing member 12 is respectively installed at both ends of the cavity structure of the metal pool body 11. Therefore, the setting of the multipole 13 can be ensured by the setting of the multipole fixing member 12, thereby ensuring the accuracy of the position setting of the multipole 13.
[0054] More specifically, a plurality of openings are provided on the inner wall of the cavity structure of the metal cell body 11 , and a plurality of terminal posts 14 are respectively disposed in the plurality of openings through the sealing rings 3 , and the plurality of terminal posts 14 are all fixedly connected to the multipole 13 .
[0055] More specifically, the functions of the terminal 14 are voltage connection, system grounding and component connection: the terminal 14 is an important component connecting the power supply and the multipole 13. The control voltage (DC and RF) is transmitted to the multipole 13 through the terminal 14 to form the required electric field. The design of the terminal 14 ensures the stability of voltage transmission and avoids the influence of voltage fluctuations on ion transmission and collision process. A part of the terminal 14 can also be used for grounding to ensure the electrical stability of the system and prevent the influence of charge accumulation on instrument performance. The terminal 14 provides a safe electrical connection to prevent high voltage from damaging operators and equipment. The terminal 14 is not only an electrical connection point, but also undertakes the physical connection function of the multipole 13 assembly to ensure the stable installation and positioning of the multipole 13 in the collision cell. As a connection point, the terminal 14 effectively integrates the multipole 13 in the collision cell with other mass spectrometer components to form a complete mass spectrometry analysis system.
[0056] More specifically, the synergistic effects of the multipole 13 and the terminal 14 include: electric field formation and control, the multipole 13 is connected to the power supply through the terminal 14 to form the required electric field, the voltage transmitted by the terminal 14 determines the electric field characteristics generated by the multipole 13, thereby affecting the motion trajectory and collision efficiency of the ions, and the stability and accuracy of the electric field depend on the design of the terminal 14 and the stability of the voltage transmission; ion transmission and detection, the multipole 13 guides and focuses the ions through the electric field so that they pass through the collision cell effectively, while the terminal 14 ensures the electrical connection and voltage stability of the multipole 13 to ensure the normal operation of the entire system. After passing through the multipole 13, the ions enter the mass analyzer for separation and detection, and the terminal 14 ensures the electrical stability and system integration of the entire process; system optimization, the design and optimization of the terminal 14 and the multipole 13 directly affect the performance of the mass spectrometer, and by precisely controlling the voltage transmitted by the terminal 14 and the electric field generated by the multipole 13, high resolution and high sensitivity of mass spectrometry analysis can be achieved.
[0057] More specifically, the port structure 2 includes a short rod assembly 22 and an electron lens 21 .
[0058] It should be noted that in the collision cell of a mass spectrometer, the short rod assembly 22 is a key structural component, which is usually used in a quadrupole mass spectrometer. The short rod assembly 22 is generally composed of four parallel metal rods. These rods can be solid or hollow, and are usually made of materials such as stainless steel or other corrosion-resistant materials. The four metal rods are arranged symmetrically, and alternating voltages are applied to each pair of opposing rods to form a dynamic electric field. The voltage applied to each pair of opposing metal rods contains direct current (DC) and alternating current (RF) components. By adjusting these voltages, the motion trajectory of the ions can be controlled. The electrode design and voltage configuration of the short rod assembly 22 directly affect the ion transmission efficiency and mass resolution.
[0059] More specifically, the functions of the short rod assembly 22 include: ion guidance, the short rod assembly 22 effectively guides ions from the collision cell to the mass analyzer part of the mass spectrometer by forming a stable electric field. The design of the electric field ensures that the ions remain on the central axis during transmission, reducing ion loss and improving signal strength; mass selection, by adjusting the voltage on the quadrupole, the short rod assembly 22 can act as a mass filter, allowing only ions within a specific mass range to pass through. This selectivity enables the mass spectrometer to distinguish different ions in complex samples and improve the precision and accuracy of the analysis; collision energy control, the electric field design of the short rod assembly 22 can also be used to control the energy of the ions, ensuring that the ions have appropriate kinetic energy when entering the collision cell to achieve efficient collision induced dissociation (CID). By adjusting the voltage and frequency, the energy distribution and collision efficiency of the ions can be precisely controlled.
[0060] More specifically, in the collision cell, ions enter through the short rod assembly 22 and collide with the inert gas molecules filling the cell, fragmenting to generate fragment ions. The short rod assembly 22 ensures that the ions maintain a stable trajectory when entering and exiting the collision cell, thereby improving the transmission efficiency of the fragment ions. The short rod assembly 22 controls the path and energy of the ions so that the mass spectrometer can accurately detect and separate ions of different mass-to-charge ratios (m / z). This precise control improves the resolution and sensitivity of the mass spectrometer and can detect low concentrations of target ions. In multi-stage mass spectrometry analysis, the short rod assembly 22 can select and transmit target ions at different stages, and provide more detailed structural information through multiple collision and fragmentation processes. The versatility of the short rod assembly 22 enables the mass spectrometer to perform efficient qualitative and quantitative analysis in complex samples.
[0061] More specifically, the short rod assembly 22 is fixed at both ends of the cavity structure of the metal pool body 11 by screws, and the electron lens 21 is set in the inner cavity of the short rod assembly 22. When the short rod assembly 22 is fixed at both ends of the cavity structure of the metal pool body 11, the electron lens 21 is sleeved in the multipole fixing member 12 through the sealing ring 3. At this time, the electron lens 21 is in the cavity structure of the metal pool body 11.
[0062] The present invention provides a method for implementing a collision cell device, which has the following beneficial effects:
[0063] The present invention provides a collision cell with a detachable design, comprising a cell body 1 and two port structures 2. The two port structures 2 are detachably arranged at both ends of the cell body 1. Due to the detachable installation method, it is easy to assemble, reduces working hours, and has good precision consistency. At the same time, due to the use of a metal cell body 11, the shielding effect is good, which is conducive to improving equipment performance, and solves the problem of the collision cell in the prior art adopting a one-time assembly design, high assembly process requirements and low efficiency.
[0064] Preferably, a sealing insulator 4 is further provided on the sealing ring 3 sleeved on the terminal 14 to perform double-layer sealing on the terminal 14 .
[0065] In a second aspect, the present invention provides a method for implementing a collision cell device, which is used to manufacture the collision cell device described in the first aspect, comprising:
[0066] S1: A metal cell body 11 with a cavity structure is obtained by processing metal materials;
[0067] S2: performing a hole-opening operation on the cavity wall of the cavity structure of the metal pool body 11 to produce a plurality of holes on the cavity wall of the cavity structure of the metal pool body 11;
[0068] S3: Installing a plurality of multipole fixing members 12 at both ends of the cavity structure of the metal cell body 11;
[0069] S4: fixing the ends of the plurality of multipole rods 13 to the plurality of multipole rod fixing members 12 installed at the two ends of the cavity structure of the metal cell body 11, thereby arranging the plurality of multipole rods 13 inside the cavity structure of the metal cell body 11;
[0070] S5: Sleeving sealing rings 3 on a plurality of terminal posts 14, and installing the terminal posts 14 with the sealing rings 3 on the cavity wall of the cavity structure of the metal cell body 11 through the plurality of openings, and fixing the terminal posts 14 to the multipole rods 13;
[0071] S6: Install the electron lens 21 in the inner cavity of the short rod assembly 22, and put a sealing ring 3 on the electron lens 21;
[0072] S7: Install the short rod assembly 22 at both ends of the cavity structure of the metal pool body 11, and fix the short rod assembly 22 and the metal pool body 11 with screws.
[0073] Specifically, the present invention provides a method for realizing a collision cell device, which is used to manufacture an efficient and stable mass spectrometer collision cell device.
[0074] In S1 of the above embodiment, a metal cell body 11 having a cavity structure is manufactured using high-strength metal materials (such as stainless steel or aluminum alloy) through precision processing (such as CNC processing). This can improve the mechanical strength and durability of the collision cell and ensure its stability under high pressure and high temperature conditions. The cavity structure provides sufficient internal space for installing the multipole 13, the terminal 14 and other internal components.
[0075] In S2 of the above embodiment, drilling operations are performed on the cavity wall of the metal cell body 11 according to predetermined positions and sizes to create openings for installing the terminal posts 14 and other components, providing necessary channels for connecting the multipole 13 and the terminal posts 14, ensuring the convenience and reliability of the electrical connection, and ensuring the alignment and stable installation of the internal components through precise hole positioning.
[0076] In S3 of the above embodiment, multipole fixing members 12 are installed at both ends of the cavity structure of the metal cell body 11 and are firmly fixed by screws or other fixing methods, providing a stable support structure for fixing the multipole 13 to ensure the accurate alignment and stability of the multipole 13. The design and installation position of the fixing members can optimize the electric field distribution of the multipole 13 and improve the performance of the collision cell.
[0077] In S4 of the above embodiment, the two ends of the multipole 13 are respectively mounted on the fixing members at both ends to ensure the uniform distribution and stable positioning of the multipole 13 inside the cell body. The stable installation of the multipole 13 ensures the uniformity of the electric field and the effective focusing of the ions, thereby improving the sensitivity and accuracy of the mass spectrometry analysis. The precise alignment and fixation of the multipole 13 avoids electric field distortion and ion scattering.
[0078] In S5 of the above embodiment, a sealing ring 3 is installed on the terminal 14 and fixed to the cavity wall of the metal cell body 11 through the opening to ensure that the terminal 14 is firmly connected to the multipole 13 and is fixed by screws or welding. The use of the sealing ring 3 ensures the sealing performance of the terminal 14, prevents gas leakage and electrical short circuit, and the firm installation and connection of the terminal 14 ensures the stability of the electric field and the reliability of the system.
[0079] In S6 of the above embodiment, the electron lens 21 is installed in the inner cavity position of the short rod assembly 22, and a sealing ring 3 is installed thereon to ensure the stability and sealing of the electron lens 21. The installation of the electron lens 21 optimizes the focusing and transmission of ions and improves the accuracy of mass spectrometry analysis. The use of the sealing ring 3 ensures the sealing performance of the electron lens 21 and prevents external interference and gas leakage.
[0080] In S7 of the above embodiment, the short rod assembly 22 is installed at both ends of the metal cell body 11 and fixed by screws to ensure its stability and accurate positioning. The installation of the short rod assembly 22 further enhances the support and stability of the multipole 13, ensuring the mechanical and electrical stability of the entire system. The screw fixation ensures the close connection between the short rod assembly 22 and the metal cell body 11, thereby improving the overall performance and reliability of the collision cell.
[0081] As can be understood, through the above steps, the present invention provides an efficient and stable method for manufacturing a collision cell assembly. This method not only ensures the precise installation and stable connection of the multipole rods 13 and the terminal posts 14, but also significantly improves the performance and reliability of the mass spectrometer by optimizing the component design and sealing process. This collision cell assembly can operate stably for long periods of time under high pressure and high temperature environments, making it suitable for a variety of high-precision mass spectrometry applications.
[0082] Preferably, before manufacturing the metal pool body 11 , the metal pool body 11 is analyzed in advance to obtain a pool body planning scheme; wherein the pool body planning scheme is used to guide subsequent manufacturing steps.
[0083] Preferably, the step of analyzing the metal pool body 11 in advance to obtain a pool body planning scheme includes:
[0084] S01: Acquire specification information of the metal pool body 11, and construct a pool body digital model for performing digital feedback on the metal pool body 11 according to the specification information of the metal pool body 11;
[0085] S02: performing position simulation processing on the terminal 14 and the multipole 13 based on the digital model of the cell body to obtain theoretical position information of the terminal 14 and the multipole 13 in the digital model of the cell body;
[0086] S03: performing position deduction processing on the opening according to the theoretical position information of the terminal 14 in the digital model of the cell body, so as to obtain the theoretical position information of the opening in the digital model of the cell body;
[0087] S04: performing position derivation processing on the multipole fixing member 12 according to the theoretical position information of the multipole in the digital model of the cell body, so as to obtain the theoretical position information of the multipole fixing member 12 in the digital model of the cell body;
[0088] S05: The theoretical position information of the terminal 14, the multipole 13, the opening, and the multipole fixing member 12 in the digital model of the cell body is taken together as the cell body planning scheme.
[0089] Specifically, detailed specification information of the metal pool body 11, including size, shape and material properties, is obtained. Based on the specification information, CAD software is used to construct a three-dimensional pool body digital model for digital feedback of the metal pool body 11. This provides an accurate three-dimensional reference model for simulating and planning the positions of various components in the collision pool. The digital model helps to discover and solve potential design problems and reduce errors and rework in actual manufacturing.
[0090] More specifically, the positions of the terminal 14 and the multipole 13 are simulated in the digital model to ensure their correct alignment and distribution in the design. The theoretical position information of the terminal 14 and the multipole 13 in the digital model is obtained through simulation to ensure the optimal position distribution of the terminal 14 and the multipole 13, improve the uniformity of the electric field and the transmission efficiency of ions, provide accurate installation guidelines, and reduce deviations during the installation process.
[0091] More specifically, based on the theoretical position information of the terminal 14 in the digital model, the actual opening position on the metal pool body 11 is deduced, the opening position is marked in the digital model, and the size and shape of the opening are determined to ensure the accuracy of the opening position, avoid errors in actual processing, improve the accuracy and stability of the installation of the terminal 14, and ensure the reliability of the electrical connection.
[0092] More specifically, based on the theoretical position information of the multipole 13 in the digital model, the actual installation position of the multipole fixture 12 on the metal cell body 11 is derived, the fixture position is marked in the digital model, and the type and size of the fixture are determined to provide an accurate fixture installation position, ensure the stability and alignment accuracy of the multipole 13, optimize the installation of the multipole 13, and improve the overall performance of the collision cell.
[0093] More specifically, the theoretical position information of the terminal 14, multipole 13, opening and multipole fixture 12 in the digital model is integrated, and based on the integrated information, a detailed cell body planning scheme is generated to guide the subsequent actual manufacturing steps. A detailed manufacturing guide is provided to ensure the accurate installation of each component in actual manufacturing. Through the simulation and deduction of the digital model, the uncertainty and error in the manufacturing process are reduced, and the manufacturing efficiency and quality are improved.
[0094] By pre-analyzing the metal cell body 11 and constructing a digital model, the present invention provides a more accurate and efficient method for manufacturing a collision cell. This method not only optimizes the mounting positions of the terminal blocks 14 and multipole rods 13, but also ensures a smooth manufacturing process through detailed cell body planning. This improvement not only improves the performance and reliability of the collision cell but also significantly reduces manufacturing costs and time.
[0095] Preferably, the step of performing position simulation processing on the terminal 14 and the multipole 13 based on the cell body digital model to obtain theoretical position information of the terminal 14 and the multipole 13 in the cell body digital model includes:
[0096] S021: Acquire specification information of the terminal 14 and the multipole 13, and construct a corresponding digital model of the terminal 14 according to the specification information of the terminal 14, and construct a corresponding digital model of the multipole 13 according to the specification information of the multipole 13;
[0097] S022: planning the arrangement of the terminal 14 and the multipole 13 based on the cell body digital model to obtain arrangement constraints of the terminal 14 and the multipole 13;
[0098] S023: performing position setting simulation processing of the digital model of the terminal 14 and the digital model of the multipole 13 based on the digital model of the cell body according to the setting restriction conditions of the terminal 14 and the multipole 13, so as to obtain several simulated setting positions of the terminal 14 and the multipole 13;
[0099] S024: performing position adaptability analysis on the plurality of simulated setting positions of the terminal 14 and the multipole 13 to obtain position adaptability between the plurality of simulated setting positions of the terminal 14 and the multipole 13;
[0100] S025: Using the simulated setting positions of the terminal 14 and the multipole 13 with the best position adaptability as theoretical position information of the terminal 14 and the multipole 13 in the digital model of the cell body.
[0101] Specifically, detailed specification information of the terminal 14 and the multipole 13, including size, shape, material properties, etc., is obtained. According to the specification information of the terminal 14 and the multipole 13, corresponding digital models of the terminal 14 and the multipole 13 are respectively constructed using CAD software, providing accurate three-dimensional digital models of the terminal 14 and the multipole 13, providing a basis for subsequent position simulation and analysis, and facilitating accurate component alignment and installation design in a virtual environment, thereby reducing errors in actual manufacturing.
[0102] More specifically, the arrangement of the terminals 14 and the multipole rods 13 is planned in the digital model of the cell body to determine their preliminary positions and arrangements. Based on the structure and design requirements of the cell body, the arrangement restrictions (such as position range, spacing requirements, etc.) of the terminals 14 and the multipole rods 13 are determined. The arrangement range and position restrictions of the terminals 14 and the multipole rods 13 are clarified to provide constraints for subsequent simulations, ensure that the arrangement meets the design requirements, and improve the uniformity of the electric field and the transmission efficiency of ions.
[0103] More specifically, based on the digital model of the cell body, various possible setting positions of the terminal 14 and the multipole 13 are simulated according to the setting constraints. Several simulated setting positions of the terminal 14 and the multipole 13 are obtained through simulation, and multiple position setting schemes are provided to facilitate the selection of the optimal configuration. Through virtual simulation, the trial and error process in actual installation is reduced, and the design efficiency is improved.
[0104] More specifically, an adaptability analysis is performed on several simulated setting positions, the actual feasibility and effect of each setting position are evaluated, and factors such as the electric field distribution, mechanical stability and installation difficulty of the terminal 14 and the multipole 13 under different position settings are analyzed to obtain the position adaptability between each setting position. Through the adaptability analysis, the most suitable setting position is screened out to ensure the optimal performance of the terminal 14 and the multipole 13, improve the reliability and rationality of the design, and avoid potential installation and use problems.
[0105] More specifically, the simulated setting positions of the terminal 14 and the multipole 13 with optimal position adaptability are determined as theoretical position information, and the optimal simulated setting positions are used as the theoretical position information of the terminal 14 and the multipole 13 in the digital model of the cell body, providing accurate theoretical position information to guide subsequent actual manufacturing and installation, ensuring the alignment and stability of the terminal 14 and the multipole 13 during actual installation, and improving the overall performance of the collision cell.
[0106] Through the above steps, the present invention provides a precise position simulation and analysis method based on a digital model. This method not only ensures the optimal placement of the terminal 14 and multipole 13 within the cell, but also significantly improves the manufacturing efficiency and performance of the collision cell through detailed simulation and adaptability analysis. This improvement not only reduces the trial and error and rework required in actual manufacturing, improves the accuracy and stability of installation, but also enhances the overall performance and reliability of the collision cell.
[0107] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.
Claims
1. A collision cell device, characterized in that: include: A tank body and two port structures, wherein the two port structures are detachably arranged at both ends of the tank body; The cell body includes a metal cell body, a plurality of multipole fixing parts, a plurality of multipole rods and a plurality of terminal posts; The metal cell body has a cavity structure inside, and the plurality of multipole rod fixing members are respectively arranged at both ends of the cavity structure of the metal cell body, and the ends of the plurality of multipole rods are respectively fixed to the multipole rod fixing members arranged at both ends of the cavity structure of the metal cell body, thereby being arranged in the cavity structure of the metal cell body; A plurality of openings are provided on the inner wall of the cavity structure of the metal cell body, and a plurality of the terminal posts are respectively arranged in the plurality of openings through sealing rings, and the plurality of the terminal posts are fixedly connected to the multipole; The port structure includes a short rod assembly and an electron lens; The short rod assembly is fixed at both ends of the cavity structure of the metal pool body by screws; The electron lens is arranged in the inner cavity of the short rod assembly. When the short rod assembly is fixedly arranged at both ends of the cavity structure of the metal pool body, the electron lens is set in the multipole fixing member through a sealing ring. At this time, the electron lens is in the cavity structure of the metal pool body.
2. The collision cell device according to claim 1, wherein A sealing insulator is also provided on the sealing ring of the terminal sleeve to perform double-layer sealing treatment on the terminal.
3. A method for implementing a collision cell device, characterized in that: A collision cell device for manufacturing the collision cell device according to claim 1 or 2, comprising: A metal pool body with a cavity structure is obtained by processing metal materials; Performing a hole-opening operation on the cavity wall of the cavity structure of the metal pool body to produce a plurality of holes on the cavity wall of the cavity structure of the metal pool body; Installing a plurality of multipole fixing members at both ends of the cavity structure of the metal cell body; respectively fixing the ends of the plurality of multipole rods to the plurality of multipole rod fixing members installed at the two ends of the cavity structure of the metal cell body, thereby arranging the plurality of multipole rods inside the cavity structure of the metal cell body; Sleeving sealing rings on a plurality of terminal posts, and installing the plurality of terminal posts with sealing rings on the cavity wall of the cavity structure of the metal cell body through the plurality of openings, and performing a fixed connection process on the terminal posts and the multipole rods; Installing the electron lens in the inner cavity of the short rod assembly and sleeve a sealing ring on the electron lens; The short rod assembly is installed at both ends of the cavity structure of the metal pool body, and the short rod assembly and the metal pool body are fixedly connected by screws.
4. The method for implementing the collision cell device as claimed in claim 3, wherein: Before manufacturing the metal pool body, the metal pool body is analyzed in advance to obtain a pool body planning scheme; wherein the pool body planning scheme is used to guide subsequent manufacturing steps.
5. The method for implementing the collision cell device according to claim 4, wherein: The steps of analyzing the metal pool body in advance to obtain a pool body planning scheme include: Acquiring specification information of the metal cell body, and constructing a cell body digital model for performing digital feedback on the metal cell body according to the specification information of the metal cell body; Performing position simulation processing of the terminal and the multipole based on the digital model of the cell body to obtain theoretical position information of the terminal and the multipole in the digital model of the cell body; Performing position deduction processing on the opening according to the theoretical position information of the terminal in the digital model of the cell body to obtain the theoretical position information of the opening in the digital model of the cell body; Performing position deduction processing on the multipole fixing member according to theoretical position information of the multipole in the digital model of the cell body to obtain theoretical position information of the multipole fixing member in the digital model of the cell body; The theoretical position information of the terminal, the multipole, the opening, and the multipole fixing member in the digital model of the cell body is used together as the cell body planning scheme.
6. The method for implementing the collision cell device according to claim 5, wherein: The step of performing position simulation processing on the terminal and the multipole based on the digital model of the cell body to obtain theoretical position information of the terminal and the multipole in the digital model of the cell body includes: Acquiring specification information of the terminal and the multipole, and constructing a corresponding digital model of the terminal according to the specification information of the terminal, and constructing a corresponding digital model of the multipole according to the specification information of the multipole; Planning the arrangement of the terminal and the multipole based on the cell body digital model to obtain arrangement constraints of the terminal and the multipole; According to the setting restriction conditions of the terminal and the multipole, a position setting simulation processing of the digital model of the terminal and the multipole is performed on the basis of the digital model of the cell body to obtain several simulated setting positions of the terminal and the multipole; Performing position adaptability analysis on the plurality of simulated setting positions of the terminal and the multipole to obtain position adaptability between the terminal and the plurality of simulated setting positions of the multipole; The simulated setting positions of the binding posts and the multipole rods having the best position adaptability are used as theoretical position information of the binding posts and the multipole rods in the digital model of the cell body.
Citation Information
Patent Citations
Collision reaction tank without charge accumulation and mass spectrometer
CN114999891A
Ion impact chamber
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