Intelligent protein centrifuge
By designing an adaptive trimming mechanism in the centrifuge, the automatic weight balance of the test tube is achieved, the centrifuge trimming problem is solved, and the efficiency and safety of the equipment are improved.
Patent Information
- Application Number
- CN202411563795.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-05
- Publication Date
- 2025-02-11
- Estimated Expiration
- 2044-11-05
AI Technical Summary
During the use of centrifuges, trimming problems affect their performance and service life, resulting in vibration, noise and rotor wear, and may even cause safety accidents.
An intelligent protein centrifugal separator is designed, using an adaptive trimming mechanism. This mechanism automatically trimmings according to the weight of the test tube by setting a cavity, runner and connecting valve in the rotor head, using the coordination of the moving parts and the transmission rod.
The automatic weight balance of the test tube is achieved, which reduces the demand for manual operation, improves work efficiency, reduces the vibration and noise of the equipment, extends the service life, and improves safety.
Smart Images

Figure CN119056595B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of centrifuges, in particular to an intelligent protein centrifuge. Background Art
[0002] A centrifuge is a machine that uses centrifugal force to separate liquids from solid particles or components in a mixture of liquids and liquids. A centrifuge is needed in the process of protein separation and purification.
[0003] However, during the use of the centrifuge, the balancing problem has always been a key factor affecting its performance and service life. Improper balancing will not only cause severe vibration and noise in the centrifuge, but also cause wear on the rotor and shaft, and may even cause safety accidents in severe cases. For this reason, we propose an intelligent protein centrifuge. Summary of the invention
[0004] In order to solve the above technical problems, the embodiment of the present application provides an intelligent protein centrifuge, including a main body, a rotor movably installed in the main body, a plurality of placement holes are opened in the rotor, and also includes;
[0005] A cover, movably mounted on the rotor, for closing the rotor;
[0006] A piston is movably arranged in the placement hole to carry the test tube;
[0007] The adaptive balancing mechanism is arranged inside the rotor and can automatically balance according to the weight of the test tube in the placement hole.
[0008] In some embodiments, a cavity is provided in the rotor, the cavity is filled with a medium, a flow channel connected to the cavity is opened at the bottom of the placement hole, the adaptive balancing mechanism includes a connecting valve arranged in the flow channel, and the side wall of the placement hole is provided with a moving part that can control the conduction and closing of the connecting valve.
[0009] In some embodiments, a side groove is provided on one side of the placement hole, and the movable part includes a movable rod slidably arranged in the side groove, an end of the movable rod located outside the side groove is provided with a slope, and the other end of the movable rod is fixedly connected to a return spring, and a connecting channel is also provided in the rotating head, and the two ends of the connecting channel are respectively connected to the side groove and the connecting valve, and a transmission rod is slidably arranged on the top of the connecting channel, a slope is provided on the top of the transmission rod, and the connecting channel is filled with water.
[0010] In some embodiments, the connecting valve includes a fixed ring fixedly arranged in the flow channel, a movable plug movably arranged on one side of the fixed ring, a support rod fixedly arranged on the movable plug, a sliding hole is opened in the fixed ring, the support rod is slidably arranged in the sliding hole, and the sliding hole is connected to the connecting channel, a connecting spring is fixedly arranged on the movable plug, and both ends of the connecting spring are respectively fixedly connected to the movable plug and the fixed ring.
[0011] In some embodiments, the length of the strut is greater than the length of the mobile plug.
[0012] In some embodiments, a connecting plug is provided on the other side of the fixing ring, and a fixing spring is provided between the connecting plug and the fixing ring to connect the two.
[0013] In some embodiments, the cover is a hollow structure with a movable groove at the bottom, a movable plate is movably arranged inside the cover, a mounting sleeve is fixedly connected to the bottom of the movable plate, and a fixed block that is plugged into the mounting sleeve is fixedly arranged on the top of the rotating head.
[0014] In some embodiments, a plurality of pressure plates are movably provided at the bottom of the cover, the pressure plates correspond to the placement holes one by one, and elastic rubber is provided on the pressure plates, the elastic rubber is fixedly connected to the cover, and a push rod is also provided on the pressure plates.
[0015] In some embodiments, a universal shaft sleeve is fixedly disposed inside the cover, a connecting shaft universally connected thereto is disposed inside the universal shaft sleeve, and the bottom of the connecting shaft is fixedly connected to the movable plate.
[0016] In some embodiments, a screw is installed in the inner thread of the universal sleeve, the top thread of the screw passes through the cover and the bottom thread passes through the universal sleeve, a sliding rod is movably arranged in the connecting shaft, a positioning rod is slidably arranged in the fixed block, an annular groove for plugging with the positioning rod is opened on the inner side of the mounting sleeve, and an annular rubber ring is arranged in the annular groove, and the end of the positioning rod close to the sliding rod is wedge-shaped.
[0017] The present invention has at least the following beneficial effects:
[0018] This intelligent protein centrifuge has an adaptive balancing mechanism. After the test tubes are placed in the placement holes, the weight of each test tube can be automatically balanced through the adaptive balancing mechanism, thereby eliminating the need for manual weighing and adding solution for balancing, thereby increasing work efficiency and facilitating use. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] Figure 1 It is a schematic diagram of the overall structure of the present invention;
[0020] Figure 2 For the present invention Figure 1 Schematic diagram of local structure;
[0021] Figure 3 This is a schematic diagram of the present invention without the main structure;
[0022] Figure 4 This is a schematic diagram of the cross-sectional structure of the rotor of the present invention;
[0023] Figure 5 For the present invention Figure 4 Side view of the structure;
[0024] Figure 6 For the present invention Figure 5 The enlarged structural diagram at A in the middle;
[0025] Figure 7 For the present invention Figure 5 The enlarged structural diagram at B in the middle;
[0026] Figure 8 This is a schematic diagram of the internal structure of the cover of the present invention;
[0027] Fig. 9 For the present invention Figure 8 Side view of the structure;
[0028] Fig.10 It is a schematic diagram of the partial cross-sectional structure of the cover and the rotating head of the present invention;
[0029] Fig.11 For the present invention Fig.10 The enlarged structural diagram at C in the middle;
[0030] Fig.12 For the present invention Fig.10 Enlarged structural diagram at D in the middle.
[0031] In the figure: 1-main body; 2-rotor; 3-placement hole; 4-cover; 5-piston; 6-adaptive balancing mechanism; 7-connecting valve; 71-fixing ring; 72-moving plug; 73-support rod; 74-sliding hole; 75-connecting spring; 8-moving part; 81-side groove; 82-moving rod; 83-reset spring; 84-connecting channel; 85-transmission rod; 9-flow channel; 10-connecting plug; 11-fixing spring; 12-movable groove; 13-movable plate; 14-mounting sleeve; 15-fixed block; 16-pressing plate; 17-thrust rod; 18-universal shaft sleeve; 19-connecting shaft; 20-screw; 21-sliding rod; 22-positioning rod; 23-ring groove. DETAILED DESCRIPTION
[0032] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0033] Example 1: Please refer to Figure 1-Figure 7 as well as Figure 8-Figure 12 The present invention provides a technical solution: an intelligent protein centrifuge, comprising a main body 1, a rotor 2 movably installed in the main body 1, a plurality of placement holes 3 are provided in the rotor 2, and a cover 4 movably installed on the rotor 2, a piston 5 movably arranged in the placement hole 3, the piston 5 is used to carry a test tube, and an adaptive balancing mechanism 6 is arranged inside the rotor 2, which can automatically balance according to the weight of the test tube in the placement hole 3.
[0034] A cavity is provided in the rotor 2, and the cavity is filled with a medium. In the present embodiment, the medium is water but is not limited thereto, and may also be other solutions with the same density as the material to be centrifuged in the test tube. A flow channel 9 connected to the cavity is provided at the bottom of the placement hole 3, and the adaptive balancing mechanism 6 includes a connecting valve 7 arranged in the flow channel 9, and a moving part 8 capable of controlling the conduction and closing of the connecting valve 7 is provided on the side wall of the placement hole 3.
[0035] A side groove 81 is provided on one side of the placement hole 3, and the moving member 8 includes a moving rod 82 slidably arranged in the side groove 81. An end of the moving rod 82 located outside the side groove 81 is provided with an inclined surface, and the other end of the moving rod 82 is fixedly connected to a reset spring 83. When the test tube is placed in the placement hole 3, the test tube will squeeze the moving rod 82 to move it into the side groove 81. A connecting channel 84 is also provided in the rotating head 2. The two ends of the connecting channel 84 are respectively connected to the side groove 81 and the connecting valve 7, and a transmission rod 85 is slidably arranged on the top of the connecting channel 84. The top of the transmission rod 85 is provided with an inclined surface, and the connecting channel 84 is filled with water. When the moving rod 82 moves toward the side groove 81, it will squeeze the transmission rod 85 to make it move. When the transmission rod 85 moves, it will squeeze the water in the connecting channel 84, and then squeeze the water into the connecting valve 7.
[0036] The connecting valve 7 includes a fixed ring 71 fixedly arranged in the flow channel 9, a movable plug 72 is movably arranged on one side of the fixed ring 71, a support rod 73 is fixedly arranged on the movable plug 72, a sliding hole 74 is opened in the fixed ring 71, the support rod 73 is slidably arranged in the sliding hole 74, and the sliding hole 74 is communicated with the connecting channel 84, and a connecting spring 75 is fixedly arranged on the movable plug 72, and the two ends of the connecting spring 75 are respectively fixedly connected to the movable plug 72 and the fixed ring 71;
[0037] The transmission rod 85 squeezes the water in the connecting channel 84 into the sliding hole 74, and then the water squeezes the support rod 73 to drive the movable plug 72 to move, so that the movable plug 72 is separated from the fixing ring 71. At this time, the fixing ring 71 is in a conducting state, and the cavity is connected to the flow channel 9.
[0038] The length of the support rod 73 is greater than that of the movable plug 72 , so that the support rod 73 can drive the movable plug 72 to separate from the fixing ring 71 while preventing the support rod 73 from moving out of the sliding hole 74 .
[0039] In summary, when in use, the material to be centrifuged is placed in a test tube, and then the test tube is placed in the placement hole 3. When the test tube is placed, the test tube will squeeze the moving rod 82 to move it into the side groove 81. When the moving rod 82 moves toward the side groove 81, it will squeeze the transmission rod 85 to move it. When the transmission rod 85 moves, it will squeeze the water in the connecting channel 84, and then squeeze the water into the sliding hole 74. Then the water will squeeze the support rod 73 to drive the moving plug 72 to move, so that the moving plug 72 is separated from the fixing ring 71. At this time, the fixing ring 71 is in a conducting state, and the cavity is connected with the flow channel 9, that is, only the placement hole 3 where the test tube is placed will be connected with the cavity. Then, the test tube with a heavier weight has a larger self-weight, which will drive the piston 5 to move downward and squeeze the water at its bottom into the cavity. Since the placement hole 3 and the flow channel 9 are of the same size and specifications, and the liquid transmission pressure is also unchanged, the piston 5 at the bottom of the remaining test tubes with smaller weight will rise under the action of water pressure, that is, the weight balance between the test tubes can be achieved through the water in the cavity, and the balance is automatically performed.
[0040] The cover 4 is a hollow structure with a movable groove 12 at the bottom. A movable plate 13 is movably arranged inside the cover 4. A mounting sleeve 14 is fixedly connected to the bottom of the movable plate 13. A fixing block 15 that is plugged into the mounting sleeve 14 is fixedly arranged on the top of the rotary head 2.
[0041] A plurality of pressing plates 16 are movably provided at the bottom of the cover 4. The pressing plates 16 correspond to the placement holes 3 one by one, and elastic rubber is provided on the pressing plates 16. The elastic rubber is fixedly connected to the cover 4. A push rod 17 is also provided on the pressing plates 16. When the cover 4 is installed on the rotor 2, the top of the test tube will press against the pressing plate 16 to move it, and the pressing plate 16 will drive the push rod 17 to move and abut against the movable plate 13.
[0042] A universal shaft sleeve 18 is fixedly arranged in the sealing cover 4 , a connecting shaft 19 universally connected thereto is arranged in the universal shaft sleeve 18 , and the bottom of the connecting shaft 19 is fixedly connected to the movable plate 13 .
[0043] A screw rod 20 is installed in the inner thread of the universal shaft sleeve 18, the top thread of the screw rod 20 passes through the cover 4 and the bottom thread passes through the universal shaft sleeve 18, a slide rod 21 is movably arranged in the connecting shaft 19, a positioning rod 22 is slidably arranged in the fixed block 15, an annular groove 23 which is plugged into the positioning rod 22 is opened on the inner side of the installation sleeve 14, and an annular rubber ring is arranged in the annular groove 23, and the end of the positioning rod 22 close to the slide rod 21 is wedge-shaped.
[0044] When installing the cover 4, after all the test tubes to be centrifuged are placed according to the principle of symmetry, the cover 4 is installed on the rotor 2, and the top of the test tube will squeeze the pressure plate 16 to drive the push rod 17 to move, and the push rod 17 will squeeze the movable plate 13 when it moves. Since the test tubes are placed according to the principle of symmetry, even if multiple push rods 17 abut the movable plate 13, the movable plate 13 is still in a horizontal state at this time, that is, the installation sleeve 14 can be smoothly plugged into the fixed block 15, and then the screw rod 20 is rotated to move it downward, the screw 20 drives the sliding rod 21 to move, and the sliding rod 21 drives the positioning rod 22 to move and be plugged into the annular groove 23, so that the installation sleeve 14 and the fixed block 15 are connected, and the installation of the cover 4 is completed immediately.
[0045] On the contrary, when the test tubes are not placed according to the principle of symmetry, the push rod 17 will push the movable plate 13 to a non-horizontal state. In this case, the mounting sleeve 14 is also in a tilted state and cannot be plugged into the fixed block 15. That is, when the test tubes are not placed according to the principle of symmetry, the cover 4 cannot be installed, resulting in the centrifuge being unusable, reminding the user to place the test tubes correctly.
[0046] Example 2: Please refer to Figure 7 , which is different from the first embodiment, is that a connecting plug 10 is provided on the other side of the fixing ring 71, and a fixing spring 11 is provided between the connecting plug 10 and the fixing ring 71 to connect the two. When the centrifuge is started, that is, when the rotor 2 rotates, under the action of centrifugal force, the connecting plug 10 will move and plug into the fixing ring 71 to close the fixing ring 71, so that the cavity is no longer connected to the placement hole 3, thereby preventing the flow of water from affecting the piston 5 and the test tube due to the change in rotation speed.
[0047] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.
[0048] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. An intelligent protein centrifuge, comprising a main body (1), a rotor (2) movably mounted in the main body (1), a plurality of placement holes (3) being provided in the rotor (2), and characterized in that: Also includes; A cover (4) movably mounted on the rotor (2) for closing the rotor (2); A piston (5) is movably disposed in the placement hole (3) and is used to carry the test tube; An adaptive balancing mechanism (6) is arranged inside the rotor (2) and can automatically balance the test tube according to the weight of the test tube in the placement hole (3); The cover (4) is a hollow structure and has a movable groove (12) at the bottom. A movable plate (13) is movably arranged inside the cover (4). A mounting sleeve (14) is fixedly connected to the bottom of the movable plate (13). A fixed block (15) pluggably matched with the mounting sleeve (14) is fixedly arranged at the top of the rotating head (2). A plurality of pressing plates (16) are movably provided at the bottom of the cover (4), the pressing plates (16) corresponding to the placement holes (3) one by one, and elastic rubber is provided on the pressing plates (16), which is fixedly connected to the cover (4), and a push rod (17) is also provided on the pressing plates (16); A universal shaft sleeve (18) is fixedly arranged inside the cover (4), a connecting shaft (19) universally connected thereto is arranged inside the universal shaft sleeve (18), and the bottom of the connecting shaft (19) is fixedly connected to the movable plate (13); The universal shaft sleeve (18) has an internal thread on which a screw rod (20) is installed. The top thread of the screw rod (20) passes through the cover (4) and the bottom thread passes through the universal shaft sleeve (18). A sliding rod (21) is movably arranged in the connecting shaft (19). A positioning rod (22) is slidably arranged in the fixed block (15). An annular groove (23) for plugging and cooperating with the positioning rod (22) is provided on the inner side of the mounting sleeve (14), and an annular rubber ring is arranged in the annular groove (23). One end of the positioning rod (22) close to the sliding rod (21) is wedge-shaped.
2. The intelligent protein centrifuge according to claim 1, characterized in that: The rotating head (2) is provided with a cavity filled with a medium, wherein the medium is water; a flow channel (9) communicating with the cavity is provided at the bottom of the placement hole (3); the adaptive balancing mechanism (6) comprises a connecting valve (7) arranged in the flow channel (9); and a moving part (8) capable of controlling the connection and closing of the connecting valve (7) is provided on a side wall of the placement hole (3).
3. The intelligent protein centrifuge according to claim 2, characterized in that: A side groove (81) is provided on one side of the placement hole (3); the moving member (8) comprises a moving rod (82) slidably arranged in the side groove (81); an end of the moving rod (82) located outside the side groove (81) is provided with an inclined surface; and the other end of the moving rod (82) is fixedly connected to a return spring (83); a connecting channel (84) is also provided in the rotating head (2); two ends of the connecting channel (84) are respectively connected to the side groove (81) and the connecting valve (7); a transmission rod (85) is slidably arranged at the top of the connecting channel (84); a top end of the transmission rod (85) is provided with an inclined surface; and the connecting channel (84) is filled with water.
4. The intelligent protein centrifuge according to claim 3, characterized in that: The connecting valve (7) comprises a fixed ring (71) fixedly arranged in the flow channel (9); a movable plug (72) is movably arranged on one side of the fixed ring (71); a support rod (73) is fixedly arranged on the movable plug (72); a sliding hole (74) is opened in the fixed ring (71); the support rod (73) is slidably arranged in the sliding hole (74); the sliding hole (74) is communicated with the connecting channel (84); a connecting spring (75) is fixedly arranged on the movable plug (72); two ends of the connecting spring (75) are respectively fixedly connected to the movable plug (72) and the fixed ring (71).
5. The intelligent protein centrifuge according to claim 4, characterized in that: The length of the support rod (73) is greater than the length of the movable plug (72).
6. The intelligent protein centrifuge according to claim 5, characterized in that: A connecting plug (10) is provided on the other side of the fixing ring (71), and a fixing spring (11) is provided between the connecting plug (10) and the fixing ring (71) to connect the two.
Citation Information
Patent Citations
Automatic balancing device of centrifugal machine
CN217699624U